Resumo Em ambientes aquáticos, a construção de barragens é considerada uma das principais ameaças para as espécies de peixes, atuando como filtro ambiental para determinados traços funcionais. Assim, embora exista certa previsibilidade na composição dos traços funcionais em reservatórios, é hipotetizado que os filtros ambientais impostos pelos processos evolutivos, ligados as características das bacias, são determinantes para a composição funcional dos traços nos reservatórios. Para isso realizamos uma PCoA utilizando a matriz de composição de traços funcionais dos reservatórios. Utilizamos a PERMANOVA para testar a diferença da composição funcional entre as bacias. Realizamos o mesmo processo para a matriz de composição de espécies para comparar os padrões. Foi possível observar que a bacia hidrográfica é um fator determinante para a estruturação funcional da assembleia de peixe em reservatórios. Quando comparadas, a estrutura funcional e taxonômica, ambas seguem o mesmo padrão, embora funcionalmente os ambientes tendem a ser mais semelhantes. Esses resultados reforçam a ideia de que reservatórios atuam como filtros para determinados traços funcionais (e.g., relacionados à reprodução, alimentação e uso de habitat), embora exista uma grande influência dos processos evolutivos ligados a característica da bacia e da origem da província ictiofaunística.

Abstract In aquatic environments, dams are considered one of the main threats to fish species, acting as an environmental filter for certain functional traits. Although there is some predictability in the composition of the functional traits in reservoirs, it is hypothesized that the environmental filters imposed by evolutionary processes, linked to the characteristics of the basins, are determinant for the functional composition of the traits in reservoirs. For this we performed a PCoA using the functional traits composition matrix of the reservoirs. We used PERMANOVA to test the difference in functional composition between basins. We performed the same process for the species composition matrix to compare the patterns. In this study, there were taxonomic and functional differences among reservoirs inserted in different basins. It was observed that the basin is a determining factor for the functional structure of fish assemblage in reservoirs. When compared, functional and taxonomic structures follow the same pattern, although functionally the reservoir tends to be more similar. These results reinforce the idea that reservoirs act as filters for functional traits (e.g., related with reproduction, feeding and habitat use), although there is a great influence of evolutionary processes related to the basin’s characteristics and origin of the ichthyofaunistic province.

Abstract Relevant mechanical parameters of asphalt composites, such as the dynamic modulus and phase angle, are obtained by means of four-point bending tests. It is a dynamic test based on the application of sinusoidal load pulses and sinusoidal displacement response. A sinusoidal response can be difficult to record due to different issues, such as noise during an experiment. In strain-controlled tests with the application of a low-load amplitude with asphalt mixtures at high temperatures composed with calcined clay, which is the case of the test carried out in this study, a relationship was observed between the apparent noise recorded and the frequencies of the beam’s natural vibration. This outcome led to the conclusion that these imperfections are not a result of failures in the procedure, but of the natural behavior of the beam. This conclusion can assist in the filtering of information to obtain better results.

OBJECTIVES: To investigate the expression levels of surface markers of activation (CD38 and HLA-DR), inhibition (PD-1, TIGIT and CD57) and co-stimulation (CD28 and CD127) on CD4+ T cells of children/adolescents with vertical HIV infection (HI patients) and HIV-uninfected (HU) controls vaccinated with the meningococcal C conjugate vaccine (MCC). METHODS: HI patients (n=12), aged 8-17 years, were immunized with two MCC injections, while HU controls (n=9), aged 5.3-10.7 years, received a single MCC dose (as per national recommendation at the time of this study, a single MCC vaccine dose should be given for healthy children and youth aged 1-18 years). The HI patients were categorized according to the combined antiretroviral therapy (cART) treatment. Blood samples were obtained before vaccination, after priming, and after the administration of a booster dose of vaccine to determine the serum bactericidal antibody (SBA) titers and the expression levels of surface markers on CD4+ T cells by flow cytometry. The levels of serum cytokines, IL-4 and CXCL-13 were also measured using Luminex kits. RESULTS: The co-expression of the TIGIT-HLA-DR-CD38 molecules increased in the CD4+ T cells of HI patients/no-cART who also showed a lower frequency of CD127+CD28+ CD4+ T cells than HI patients/cART and HU group subjects. There were significant negative correlations between the frequency of exhausted CD4+ T cells and the SBA response. IL-4 levels were higher in HI patients/cART and positively correlated with SBA titers but negatively associated with the expression of exhaustion markers. Moreover, the CXCL-13 levels were positively correlated with the exhausted CD4+ T cells. CONCLUSION: The results of our study suggest that the co-expression of exhaustion markers and/or loss of co-stimulatory molecules influence the SBA response in HI patients.

Resumo Os óxidos de molibdênio são materiais tecnológicos muito interessantes, que apresentam diversos usos industriais. A adição de um segundo metal pode melhorar suas propriedades catalíticas, bem como alterar o comportamento eletrônico. Várias metodologias para adicionar um segundo metal podem ser encontradas na literatura, porém a comparação entre elas é dificilmente encontrada. Aqui duas rotas de processamento foram aplicadas para a síntese de óxido de molibdênio com adição de cobalto: via sólida e via úmida. Molibdato de amônio e nitrato de cobalto foram usados como materiais de partida e a adição de cobalto foi realizada antes da calcinação. Os materiais iniciais foram caracterizados por MEV, FTIR, FRX e DRX. Os produtos de calcinação foram avaliados por MEV, FRX, DRX e espectroscopia UV-vis. Produto calcinado cuja dopagem foi realizada via estado sólido apresentou menor tamanho de cristal (~25 nm), maior retenção de cobalto (desvio, δ ~10%) e band gap levemente menor em comparação com aquele dopado por via úmida (~40 nm e δ>11%).

Abstract Molybdenum oxides are very interesting technologic materials, which present several industrial uses. The addition of a second metal may enhance its catalytic properties as well as change electronic behavior. Several methodologies for adding a second metal can be found in the literature, however, the comparison between them is hardly ever found. Here two processing routes were tested for the synthesis of molybdenum oxide with cobalt addition: solid-state and wet routes. Ammonium molybdate and cobalt nitrate were used as starting materials and cobalt addition was carried out before calcination. Starting materials were characterized by SEM, FTIR, XRF, and XRD. Calcination products were evaluated by SEM, XRF, XRD and UV-vis spectroscopy. Calcined products whose doping was performed via solid-state presented smaller crystal size (~25 nm), larger cobalt retention (deviation, δ ~10%) and slightly smaller band gap in comparison to those doped via the wet route (~40 nm and δ>11%).

In this work, the allantoin was encapsulated with galactomannan extruded from Delonyx regia, by the spray drying technique. The microparticles obtained were structurally characterized by infrared spectroscopy (IR), thermal analysis, scanning electron microscopy (SEM) and the controlled release profile was evaluated. The results of IR suggested the formation of the polymeric wall of the microcapsules and SEM revealed spherical particles with an average size range of 2.84 ± 0.41 µm. X-ray diffraction showed the loss of crystallinity of the active after encapsulation and differential explanatory calorimetry exhibited the loss of its peak melt. The encapsulation efficiency for the microparticles was approximately 84% for the different environmental conditions. The coating of allantoin with the biopolymer promoted a gradual release of the drug over a period of 6 hours and these results are in accordance with the Brazilian Pharmacopoeia. The set of results obtained in this work is relevant and accredits the system developed as a possible alternative for the formation of encapsulated natural drugs destined to possible treatments of cutaneous cellular regeneration.

RESUMO Objetivo Esta pesquisa teve como objetivo verificar as associações entre o consumo de nutrientes antioxidantes e as alterações lipídicas e o risco cardiometabólico em adolescentes. Métodos Trata-se de estudo transversal com 327 adolescentes de 14 a 19 anos de idade. Investigaram-se dados sociodemográficos, antropométricos, pressóricos, bioquímicos e de consumo alimentar. O risco cardiometabólico foi calculado por meio da agregação dos fatores de risco, expressa pela soma dos escores Z. Realizou-se a regressão de Poisson para estimar as razões de prevalência. Resultados O baixo consumo de zinco associou-se a elevados níveis de CT e triglicérides para os meninos, e a níveis baixos de HDL-c e elevados de LDL-c e CT para as meninas, demonstrando risco. Além disso, a baixa ingestão de cobre associou-se a altos níveis de triglicérides e risco cardiometabólico para as meninas. A razão de prevalência nos níveis elevados de LDL-c, CT e risco cardiometabólico foi maior entre os adolescentes que apresentavam baixa ingestão de vitamina A. Foram observadas também associações, no sexo feminino, da menor ingestão de vitamina A com altos níveis de triglicérides. A baixa ingestão de vitamina C nos meninos mostrou associações com LDL-c e triglicérides elevado, enquanto nas meninas essa vitamina associou-se com menores níveis de HDL-c. O baixo consumo de vitamina E, para as meninas, apresentou associações com níveis baixos de HDL-c e elevados de CT. Conclusão As associações entre os micronutrientes antioxidantes e as alterações lipídicas e risco cardiometabólico ressaltam a importância de estimular o consumo de alimentos que sejam fonte desses nutrientes, com o objetivo de modular as alterações lipídicas e o risco cardiometabólico.

ABSTRACT Objective This study aimed at validating the associations between the consumption of antioxidant nutrients as well as lipid alterations and cardiometabolic risks in adolescents. Methods This cross-sectional study included 327 adolescents aged 14-19 years. Sociodemographic and dietary information, anthropometric and blood pressure measurements, and biochemical data were obtained. Cardiometabolic risk was calculated by aggregating the risk factors, which were expressed as the sum of Z-scores. Poisson regression was performed to estimate the prevalence ratios. Results In boys, low intake of zinc was associated with elevated total cholesterol and triglyceride levels, whereas it was associated with low high-density lipoprotein cholesterol levels and high low-density lipoprotein cholesterol and total cholesterol levels in girls, thus indicating a cardiometabolic risk. Furthermore, low intake of copper was associated with high triglyceride levels and cardiometabolic risk in girls. The high prevalence ratios of high low-density lipoprotein cholesterol and total cholesterol levels and cardiometabolic risk were higher in those with low intake of vitamin A. Among girls, associations were also observed between lower intake of vitamin A and high triglyceride levels. Low intake of vitamin C among boys was associated with elevated high low-density lipoprotein cholesterol and triglyceride levels. Among girls, the intake of this vitamin was associated with lower low high-density lipoprotein cholesterol levels. In girls, low intake of vitamin E was associated with low low high-density lipoprotein cholesterol levels and high total cholesterol levels. Conclusion The associations between antioxidant micronutrients as well as lipid alterations and cardiometabolic risk emphasize the importance of encouraging the consumption of foods that are rich in these nutrients to modulate lipid alterations and cardiometabolic risk.

An electrophilic iodocyclization reaction involving alkynylated 2-iodoanisoles and molecular iodine in the presence of sodium bicarbonate was developed and diiodo-functionalized benzo[b]furans were obtained in yields from 45 to 99%.

Abstract Cyanobacteria is a remarkable group of prokaryotic photosynthetic microorganisms, with several genera capable of fixing atmospheric nitrogen (N2) and presenting a wide range of morphologies. Although the nitrogenase complex is not present in all cyanobacterial taxa, it is spread across several cyanobacterial strains. The nitrogenase complex has also a high theoretical potential for biofuel production, since H2 is a by-product produced during N2 fixation. In this review we discuss the significance of a relatively wide variety of cell morphologies and metabolic strategies that allow spatial and temporal separation of N2 fixation from photosynthesis in cyanobacteria. Phylogenetic reconstructions based on 16S rRNA and nifD gene sequences shed light on the evolutionary history of the two genes. Our results demonstrated that (i) sequences of genes involved in nitrogen fixation (nifD) from several morphologically distinct strains of cyanobacteria are grouped in similarity with their morphology classification and phylogeny, and (ii) nifD genes from heterocytous strains share a common ancestor. By using this data we also discuss the evolutionary importance of processes such as horizontal gene transfer and genetic duplication for nitrogenase evolution and diversification. Finally, we discuss the importance of H2 synthesis in cyanobacteria, as well as strategies and challenges to improve cyanobacterial H2 production.

Resumo Na análise mecanicista das misturas asfálticas, o módulo complexo é um parâmetro de importância fundamental para formulação de modelos constitutivos de sua estrutura, pois retrata tanto a parcela do comportamento elástico, decorrente dos agregados, quanto o comportamento viscoso, advindo do ligante asfáltico. A primeira é representada pelo módulo dinâmico e a segunda pelo ângulo de fase. Ambos os parâmetros dependem da temperatura e da frequência de carregamento. Como não é possível medi-los para toda temperatura e carregamento, obtêm-se funções que representem esses parâmetros, utilizando-se tanto ajustes genéricos como modelos de previsão do comportamento. Analisou-se a viabilidade de diversas modelagens referente ao módulo dinâmico de compósitos asfálticos com argila calcinada, obtidos mediante ensaios de flexão a quatro pontos. Observou-se que podem ser utilizados com eficiência tanto regressões múltiplas não lineares quanto as curvas mestras, com translação entre frequência e temperatura. Equações fenomenológicas também podem ser empregadas com precisão, por meio das quais é possível extrapolar os dados, obtendo-se o valor de equilíbrio do módulo dinâmico quando a frequência tende ao infinito.

Abstract In the mechanistic analysis of asphalt mixtures, the complex modulus is a fundamental parameter for the formulation of constitutive models of its structure, since it represents the portion of elastic behavior, typical of the aggregate of the mixture, as well the viscous behavior, due to the asphaltic binder. The first is represented by the dynamic modulus and the second by the phase angle. Both parameters depend on the temperature and the loading rate. As it is not possible to measure them for all temperature and loading, functions that represent these parameters are obtained, using both generic fitting as predictive models. Various models for the dynamic modulus of asphalt composites with calcined clay, obtained by four-point bending tests, were analyzed. It is observed that both method, multiple nonlinear regressions as well mastercurves, can be used efficiently, with translation of frequency and temperature. Phenomenological equations can also be used accurately, by which it is possible to extrapolate the data, yielding the equilibrium value of the dynamic modulus when the frequency tends to infinity.

A reação de acoplamento entre 2,6-diiodoanisóis e alcinos terminais usando Pd(PPh3)2Cl2 e CuI como catalisadores e diisopropilamina como base em tolueno a temperatura ambiente por 12 h produziu seletivamente 2-iodoanisóis aquinilados, em rendimentos de bons a excelentes (52-95%), os quais são blocos de construção úteis com potencial aplicação na síntese de benzo[b]furanos funcionalizados.

The coupling reaction between 2,6-diiodoanisoles and terminal alkynes using Pd(PPh3)2Cl2 and CuI as catalysts and diisopropylamine as base in toluene at room temperature for 12 h produced selectively alkynylated 2-iodoanisoles, in good to excellent yields (52-95%), which are useful building blocks with potential application in the synthesis of functionalized benzo[b]furans.

The aim of present study was to describe the frequency of lipodystrophy syndrome associated with HIV (LSHIV) and factors associated with dyslipidemia in Brazilian HIV infected children. HIV infected children on antiretroviral treatment were evaluated (nutritional assessment, physical examination, and laboratory tests) in this cross-sectional study. Univariate analysis was performed using Mann-Whitney test or Fisher's exact test followed by logistic regression analysis. Presence of dyslipidemia (fasting cholesterol >200 mg/dl or triglycerides >130 mg/dl) was the dependent variable. 90 children were enrolled. The mean age was 10.6 years (3-16 years), and 52 (58%) were female. LSHIV was detected in 46 children (51%). Factors independently associated with dyslipidemia were: low intake of vegetables/fruits (OR = 3.47, 95%CI = 1.04-11.55), current use of lopinavir/ritonavir (OR = 2.91, 95%CI = 1.11-7.67). In conclusion, LSHIV was frequently observed; inadequate dietary intake of sugars and fats, as well as current use of lopinavir/ritonavir was associated with dyslipidemia.

O presente estudo tem como principal objetivo a determinação do módulo dinâmico uniaxial, propiciando a obtenção de uma propriedade viscoelástica capaz de simular uma condição mais realística do que ocorre nos pavimentos, por força da demanda do tráfego. Trata-se de pesquisa inédita, com a participação do agregado sinterizado de argila calcinada (ASAC) em misturas asfálticas, visando a fomentar opção factível à pavimentação de vias urbanas no município de Manaus. Utilizaram-se, também, os seguintes materiais: seixo rolado, substituto regional à carência de material pétreo (referência), duas areias naturais, além de uma areia artificial proveniente da britagem de argila calcinada e o cimento asfáltico de petróleo 50/70 comercializado no estado do Amazonas. Na composição mineral das misturas, empregou-se o método Bailey, a enfatizar o intertravamento de seu esqueleto pétreo, a fim de se assegurar maior resistência à deformação permanente, principal patologia apresentada pelos pavimentos locais. Os resultados revelaram que, em altas temperaturas e em baixas frequências, as misturas com ASAC apresentaram-se mais rígidas relativas às misturas com seixo, indicando menos susceptibilidade às deformações permanentes, enquanto que, em baixas temperaturas e em altas frequências, o processo se inverteu e os compósitos com o agregado aluvionar passaram a expor valores de módulo dinâmico superiores aos das misturas com material alternativo. A avaliação mecânica, por meio do ensaio de Lottman, evidenciou que ambos os compósitos (com seixo e ASAC), apesar de apresentarem discretas perdas de resistência, preservaram suas estruturas, em consequência do efeito da umidade induzida. A inserção de areia artificial nas misturas asfálticas, a par de satisfatória quanto ao desempenho mecânico, minimiza a extração do recurso natural.

The present study has as main objective the determination of uniaxial dynamic module, allowing obtaining viscoelastic properties able to simulate a more realistic condition that occurs in pavements, under the traffic demand. This is an original research, with the participation of the sintered calcined clay aggregate (SCCA) in asphalt mix, in order to promote feasible option for paving urban roads in the city of Manaus. We used also the following materials: river bed pebbles, substitute, given the lack of regional stone material (reference), two natural sands, plus artificial sand from the crushing plant calcined clay and asphalt cement 50/70 sold in the state of Amazonas. For mineral composition of the mixtures, we used the Bailey method, to emphasize the interlocking of their stony skeleton in order to ensure greater resistance to permanent deformation, primary pathology presented by local pavements. The results revealed that, at high temperatures and low frequencies, mixtures with SCCA were more rigid than those mixed with pebble, indicating less susceptibility to permanent deformation, while at low temperatures and at high frequencies, the process is reversed and composites with added alluvial began to expose dynamic modulus values higher than those of mixtures with alternative material. The mechanical evaluation by means of the Lottman assay, showed that both composites (with pebble and SCCA) techniques, although with slight loss of resistance, preserved their structures, due to the effect of moisture induced. The insertion of artificial sand in asphalt mix, beyond satisfactory on the mechanical performance, minimizes natural resource extraction.

Ante a carência de materiais pétreos na região amazônica (déficit prejudicial ao seu emprego, nas obras civis, como agregado graúdo), desenvolveu-se pesquisa científico-tecnológica voltada a materiais alternativos, por meio da qual se constatou a viabilidade técnica do Agregado Sinterizado de Argila Calcinada - ASAC, na composição de misturas asfálticas destinadas aos pavimentos rodoviários amazônicos. Por outro lado, levantamentos demonstraram abundância na Amazônia da matéria para a sua confecção, que permitirá sua obtenção em larga escala, mesmo em locais de difícil acesso, motivos pelos quais se mostra indispensável aferir os custos do seu processo produtivo. Estabeleceu-se metodologia de análise de custos de confecção de produtos de cerâmica vermelha, que pode ser utilizado para produção do ASAC. Em junho de 2012 o exame preliminar constatou para o ASAC preço 40% superior ao do seixo (tradicional opção regional ao agregado pétreo), ao passo que, quanto ao agregado tradicional, detectou-se preço muito abaixo da média usual, com tendência de recuperação, de sorte que a produção do agregado sinterizado apresenta-se vantajosa, no médio e longo prazos. Com efeito, a análise mais detalhada, em que o processo produtivo foi adaptado à produção do agregado artificial, apontou fato promissor: o preço final com valor 24% acima do seixo rolado. No contexto da produção para a aplicação direta na obra civil, a situação se inverte, porquanto apenas os custos diretos de produção compõem o custo do ASAC, revelando-se 34,5% inferior ao preço do agregado aluvionar, este, ressalta-se, abaixo da sua média histórica. Computando-se custos adicionais de transporte para o seixo rolado, quando o local da obra é distante dos centros comerciais, a vantagem financeira do ASAC aumenta de forma expressiva, a ponto de alcançar preço 77% inferior ao do seixo rolado (por exemplo, para uma distância média de 400 km).

Faced with a shortage of stone materials in the Amazon region (deficit detrimental to their employment in civil works such as coarse aggregate), developed scientific-technological research focused on alternative materials, through which verified the feasibility of Aggregate Sintered Calcined Clay - ASAC, to composition of asphalt mixtures for road pavements to Amazon. Moreover, surveys showed plenty of matter in the Amazon for its confection, which allow obtaining a large scale, even in hard to reach places, reasons is indispensable to assess the costs of its production process. It was established methodology for analyzing cost of making red ceramic products, which can be used to produce the ASAC. In June 2012, the preliminary examination found, for ASAC, price 40% higher than the pebble (traditional regional option to aggregate stony), while, on the traditional aggregate, we detected a price far below the usual average, with recovery trend, so that the production of sintered aggregate proved to be advantageous in the medium and long term. Indeed, the further analysis, in which the production process was adapted for production of the artificial aggregate, appointed fact promising: the price final value 24% above the pebble. In the context of production for direct application in civil work, the situation is reversed, since only the direct production costs comprise the cost of ASAC, revealing 34.5% less than the price of alluvial aggregate, this, it is emphasized, below its historical average. Computing the additional transport costs to the pebble, when the construction site is far from the shopping centers, the financial advantage of the ASAC increases significantly, to the point of achieving price 77% lower than the pebble (e.g. for an average distance of 400 km).

Estudos sobre as taxas de prevalência da esclerose múltipla (EM) no mundo têm fornecido importantes evidências do papel da inter-relação dos fatores genéticos e ambientais determinando estas frequências. Como o Brasil é um país muito extenso e com populações de diversas origens étnicas, supõe-se que a frequência da EM seja variável em suas diferentes regiões. Objetivo: Determinar a taxa de prevalência da esclerose múltipla (EM) em Belo Horizonte, capital do estado de Minas Gerais, no sudeste do Brasil. Métodos: Nós usamos seis fontes para a identificação dos pacientes que preenchiam os critérios diagnósticos de EM clinicamente definida de acordo com o Comitê de Poser. Resultados: A taxa de prevalência encontrada foi de 18,1/100.000 habitantes. Conclusões: A prevalência em Belo Horizonte de EM é semelhante à encontrada nos estudos em São Paulo e Botucatu, duas outras cidades na região sudeste do Brasil habitadas por populações com similar origem étnica.

Investigations on the prevalence rates of multiple sclerosis (MS) around the world have yielded important clues on the interplay between genetic susceptibility and environmental factors. As Brazil is a huge country laid on many latitudes and inhabited by population with distinct ethnic backgrounds, it might be assumed that the frequency of MS varies in its different regions. Objective: To determine the prevalence rate of MS in Belo Horizonte, the capital of the State of Minas Gerais, Southeastern Brazil. Methods: We used six sources to draw up a provisional list of identified cases of MS. Only patients with diagnosis of clinically definite MS according to Poser Committee criteria were included. Results: The calculated crude MS prevalence was 18.1/100,000 inhabitants. Conclusions: The MS prevalence in Belo Horizonte is similar to that found in São Paulo and Botucatu, two other cities in southeastern Brazil with similar ethnic background.

Tendo em vista a necessidade do mercado brasileiro por ligantes que minimizem a prematura falência estrutural dos revestimentos nas vias urbanas, a modificação do cimento asfáltico de petróleo (CAP 50/70) constitui uma excelente opção tecnológica. Nesta pesquisa utilizou-se 2% p/p do copolímero de estireno-butadieno-estireno (SBS) e 2% p/p de fibra natural da casca dos frutos de Couepia edulis (Prance), conhecida como castanha de cutia, material vegetal com característica de reforço e biodisponibilidade na região Amazônica. Os efeitos oxidativos e térmicos, bem como as características físicas dos materiais asfálticos modificados, foram estudados e comparados ao ligante convencional, utilizando-se ensaios estabelecidos pela Agência Nacional de Petróleo, Gás Natural e Biocombustíveis (ANP) e análise térmica - termogravimetria (TG), a fim de determinar as propriedades de degradação e estabilização térmica. Os resultados para os ligantes modificados, confrontados ao ligante tradicional, apresentaram: maior resistência ao envelhecimento, melhorias evidenciadas pelo aumento da consistência, ponto de amolecimento, além da excelente estabilidade térmica em toda faixa de temperatura de utilização (10 ºC a 80 ºC) e aplicação (130 ºC a 170 ºC) dos cimentos asfálticos de petróleo, fornecendo uma opção ao pavimento regional.

There is a need in the Brazilian market for asphalt binders that minimize premature structural failure of the coatings on urban roads, and the modification of asphalt cement oil (CAP 50/70) is an excellent option. In this research we used 2% w/w of the styrene - butadiene-styrene (SBS) copolymer and 2% w/w of natural fiber from Couepia edulis (Prance), known as cutia chesnut, which is a plant from the Amazon region with strengthening properties. The oxidative and thermal effects, as well as the physical characteristics of the asphalt modified materials, were studied and compared to the conventional binder, using the tests set by the National Agency of Petroleum, Natural Gas and Biofuels (ANP) and thermal analysis - thermogravimetry (TG) to determine the properties of thermal degradation and stabilization. In comparison with the traditional binders, the modified ones exhibited increased resistance to aging, evidenced by an increase in consistency, softening point and excellent thermal stability in the whole range of operating (10 ºC to 80 ºC ) and application (130 ºC to 170 ºC) temperatures for the asphalt cement oil, providing an option for regional pavements.