ABSTRACT This study aimed to identify factors associated with colonization by community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) in adult patients admitted to a Brazilian hospital. This is a cross-sectional study, in which patients underwent a nasal swab and were asked about hygiene behavior, habits, and clinical history. Among the 702 patients, 180 (25.6%) had S. aureus and 21 (2.9%) MRSA. The factors associated with MRSA colonization were attending a gym (OR 4.71; 95% CI; 1.42 – 15.06), smoking habit in the last year (OR 2.37; 95% CI; 0.88 – 6.38), previous hospitalization (OR 2.18; CI 95%; 0.89 – 5.25), and shared personal hygiene items (OR 1.99; 95% CI; 0.71 – 5.55). At the time of admission, colonization by CA-MRSA isolates was higher than that found in the general population. This can be an important public health problem, already endemic in hospitals, whose factors such as those associated with habits (smoking cigarettes) and behaviors (team sports practice and activities in gyms) have been strongly highlighted. These findings may help developing infection control policies, allowing targeting patients on higher-risk populations for MRSA colonization. communityassociated community methicillinresistant methicillin resistant CAMRSA CA (CA-MRSA hospital crosssectional cross sectional behavior history 70 18 25.6% 256 25 6 (25.6% S 2 2.9% 29 9 (2.9% OR 4.71 471 4 71 95 142 1 42 1.4 15.06, 1506 15.06 , 15 06 15.06) 2.37 237 37 088 0 88 0.8 6.38, 638 6.38 38 6.38) 2.18 218 089 89 5.25, 525 5.25 5 5.25) 1.99 199 99 071 0.7 5.55. 555 5.55 . 55 5.55) admission population problem hospitals cigarettes team gyms highlighted policies higherrisk risk 7 25.6 (25.6 2.9 (2.9 4.7 47 14 1. 150 15.0 2.3 23 3 08 8 0. 63 6.3 2.1 52 5.2 1.9 19 07 5.5 25. (25. 2. (2. 4. 15. 6. 5. (25 (2 (

ABSTRACT Background: The intensity of dengue virus (DV) replication and circulating non-structural protein 1 (NS1) levels may promote changes in the human immune response and favor severe forms of infection. We investigated the correlations between NS1 with CXCL-8, CXCL-10, IFN-γ, and IL-12p40 serum levels, and IFN-γ receptor α chain (CD119) expression, and CXCL10 production by peripheral blood mononuclear cells (PBMCs) stimulated with recombinant IFN-γ in DV-infected patients with different clinical forms. Methods: Dengue virus NS1, CXCL-8, CXCL-10, IFN-γ, and IL-12p40 serum levels were measured in 152 DV-infected patients with different clinical forms and 20 non-infected individuals (NI) using enzyme-linked immunosorbent assay (ELISA). In addition, we investigated the CXCL-10 production after in vitro IFN-γ stimulation of PBMCs from 48 DV-infected individuals (with different clinical forms of dengue fever) and 20 NI individuals using ELISA, and CD119 expression on CD14+ cells with flow cytometry. Results: Patients with dengue hemorrhagic fever (DHF) had significantly higher NS1, CXCL-8, and CXCL-10 serum levels than those with classic dengue fever (DF). The response of PBMCs to IFN-γ stimulation was lower in patients with DHF than in those with DF or dengue with complications (DWC), with lower CD119 expression and reduced CXCL-10 synthesis. In addition, these alterations are associated with high NS1 serum levels. Conclusions: Patients with DHF reported high NS1 levels, low CD119 expression, and low CXCL-10 synthesis in PBMCs, which may be associated with infection progression and severity. Background DV (DV nonstructural non structural NS (NS1 CXCL8, CXCL8 CXCL 8, 8 CXCL-8 CXCL10, 10, 10 IFNγ, IFNγ IFN γ, γ IL12p40 ILp IL 12p40 p IL-12p4 CD (CD119 CXCL1 (PBMCs DVinfected infected Methods 15 2 noninfected (NI enzymelinked enzyme linked ELISA. ELISA . (ELISA) addition CXCL-1 4 CD11 CD14 cytometry Results (DHF DF. (DF) DWC, DWC , (DWC) Conclusions severity (NS CXCL- IL12p4 12p4 IL-12p (CD11 (ELISA CD1 (DF (DWC IL12p 12p (CD1 (CD

Abstract Objective Eclampsia is a hypertensive disorder that occurs during pregnancy and can lead to death. The literature has gaps by not providing comprehensive data on the epidemiology of the disease, restricting analysis to limited temporal intervals and geographical locations. This study aims to characterize the epidemiological profile of women who died from eclampsia in Brazil from 2000 to 2021. Methods The maternal mortality data were obtained from the Sistema de Informações sobre Mortalidade, with the following variables of interest selected: “Federative Unit,” “Year,” “Age Range,” “Race/Color,” and “Education Level.” The collection of the number of live births for data normalization was conducted in the Sistema de Informações sobre Nascidos Vivos. Statistical analyses were performed using GraphPad Prism, calculating odds ratio for variables and fixing number of deaths per 100,000 live births for calculating maternal mortality ratio (MMR). Results There was a downward trend in maternal mortality rate during the study period. Maranhão stood out as the federative unit with the highest MMR (17 deaths per 100.000 live births). Mothers aged between 40 and 49 years (OR = 3.55, CI: 3.11–4.05) presents higher MMR. Additionally, black women showed the highest MMR (OR = 4.67, CI: 4.18–5.22), as well as mothers with no educational background (OR = 5.83, CI: 4.82–7.06). Conclusion The epidemiological profile studied is predominantly composed of mothers with little or no formal education, self-declared as Black, residing in needy states and with advanced aged. These data are useful for formulating public policies aimed at combating the issue. death disease locations 200 2021 Mortalidade selected Federative Unit, Unit Year, Year “Year, Age Range, Range Race/Color, RaceColor Race Color “Race/Color, Education Level. Level Vivos Prism 100000 100 000 100,00 . (MMR) period 17 (1 100.00 births. births) 4 OR 355 3 55 3.55 CI 3.11–4.05 311405 11 05 Additionally 467 67 4.67 4.18–5.22, 418522 4.18–5.22 , 18 5 22 4.18–5.22) 583 83 5.83 4.82–7.06. 482706 4.82–7.06 82 7 06 4.82–7.06) education selfdeclared self declared Black issue 20 202 “Year Race/Color “Race/Color 10000 10 00 100,0 (MMR 1 ( 100.0 35 3.5 3.11–4.0 31140 0 46 6 4.6 41852 4.18–5.2 2 58 8 5.8 48270 4.82–7.0 1000 100, 100. 3. 3.11–4. 3114 4. 4185 4.18–5. 5. 4827 4.82–7. 3.11–4 311 418 4.18–5 482 4.82–7 3.11– 31 41 4.18– 48 4.82– 3.11 4.18 4.82 3.1 4.1 4.8

Resumo O artigo analisou o processo de precarização das relações de trabalho no setor da saúde, demonstrando como essa situação gerou sofrimento dos trabalhadores. O texto buscou registrar como a adoção institucional das concepções econômicas neoliberais, de redução das políticas sociais de Estado, acopladas a um histórico de rejeição cultural aos direitos trabalhistas, proporcionou a atração dos mecanismos de precarização do trabalho, notadamente, a terceirização da mão de obra e da prestação de serviços. No segundo momento, o texto aponta as impropriedades jurídicas cometidas, apresentando as consequências da fragilização do vínculo jurídico nas condições de trabalho desses trabalhadores, principalmente no que se refere às jornadas de trabalho e a remuneração, destacando-se, também, o quanto a disseminação desses vínculos representou um fator de rebaixamento geral dos salários e direitos trabalhistas e previdenciários no setor. Foram apresentados, ainda, dados das pesquisas da Fiocruz sobre condições de trabalho durante a pandemia. Conclui mostrando a urgência de se resgatarem os institutos jurídicos trabalhistas que foram abandonados no percurso histórico estudado, para direcionar a novo rumo as políticas públicas na saúde. saúde trabalhadores neoliberais Estado notadamente serviços momento cometidas remuneração destacandose, destacandose destacando se, destacando-se também apresentados ainda pandemia estudado

Abstract The present article analyzed the process of precarious work relations in the health sector, demonstrating how this situation generated illness and suffering among workers. The text sought to register how the institutional adoption of neoliberal economic conceptions, of the reduction of State social policies, coupled with a history of cultural rejection of labor rights, provided the attraction of mechanisms of precarious work for the public sector, notably, the outsourcing of labor and the provision of services. In a second moment, the text points out the legal improprieties committed, presenting the consequences of the weakening of the legal bond in the working conditions of these workers, mainly regarding working hours and remuneration, also highlighting how much the dissemination of these links represented a factor of a general reduction in wages and labor and social security rights in the sector. Data from Fiocruz surveys on working conditions during the pandemic were also presented. The article concludes by showing the urgency of rescuing the legal labor institutes that were abandoned in the historical path studied in order to guide the public health policies in a new direction. sector workers conceptions notably services moment committed remuneration presented direction

Resumo A pesquisa tem por objetivo descrever o perfil sociodemográfico e de saúde dos profissionais de enfermagem no contexto da pandemia da COVID-19 e propõe uma análise reflexiva sobre a essencialidade da categoria frente às demandas intrínsecas dos pacientes e do sistema de saúde brasileiro, especialmente, no contexto da emergência de saúde pública deflagrada pelo avanço exponencial do vírus SARS-CoV-2. O estudo revela a relação entre as injustiças históricas e os diferentes tipos de desigualdade que afetam e causam a vulnerabilidade da profissão, com fulcro na apresentação de potenciais perspectivas decorrentes desse processo histórico e dos acontecimentos recentes. COVID19 COVID 19 COVID-1 brasileiro especialmente SARSCoV2. SARSCoV2 SARSCoV SARS CoV 2. 2 SARS-CoV-2 profissão recentes COVID1 1 COVID- SARS-CoV- SARS-CoV

Abstract The present study aims to describe the sociodemographic and health profile of nursing professionals in the context of the COVID-19 pandemic and propose a reflective analysis on the essentiality of the category facing the intrinsic demands of patients and the Brazilian health system, especially in the context of the public health emergency triggered by the exponential advance of the SARS-CoV-2 virus. This study reveals the relationship between historical injustices and the different types of inequality that impacted and caused the vulnerability of the profession, with an emphasis on the presentation of potential perspectives arising from this historical process and recent events. COVID19 COVID 19 COVID-1 system SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- virus profession events COVID1 1 COVID- SARS-CoV

Resumo O artigo investiga a correlação entre engajamento e qualidade de vida no trabalho dos profissionais de enfermagem de um hospital público do interior do estado de São Paulo, no início da pandemia de COVID-19. Estudo transversal, descritivo e correlacional, com profissionais de enfermagem, realizado entre dezembro de 2020 e janeiro de 2021. Foram utilizadas as versões brasileiras da Utrecht Work Engagement Scale (UWES) e da Escala de Avaliação da Qualidade de Vida no Trabalho (QVT), segundo modelo de Walton. Os profissionais de enfermagem apresentaram correlação forte e positiva (r≥0.70) entre o domínio integração social da QVT e a dimensão vigor da UWES (r=0,88; p=<0,001); correlação positiva moderada (r≥0.40≤0.69) entre as condições de trabalho (QVT) e as dimensões vigor (r=0,40; p=<0,001), dedicação (r=0,40; p=<0,001) e escore geral (r=0,41; p=<0,001) da UWES. As correlações foram positivas e fracas (r≤0.39) para os demais domínios da QVT e as dimensões da UWES. Concluiu-se que os profissionais com níveis satisfatórios de qualidade de vida tendem a ter níveis mais altos de engajamento no trabalho. No início da pandemia de COVID-19, os profissionais de enfermagem estavam fortemente engajados e satisfeitos com sua qualidade de vida no trabalho. Paulo COVID19. COVID19 COVID 19. 19 COVID-19 transversal correlacional 202 2021 (UWES QVT, , Walton r≥0.70 r070 r 0 70 (r≥0.70 r=0,88 r088 88 (r=0,88 p=<0,001 p0001 p 001 r≥0.40≤0.69 r040069 40 69 (r≥0.40≤0.69 (QVT r=0,40 r040 (r=0,40 p=<0,001, r=0,41 r041 41 (r=0,41 r≤0.39 r039 39 (r≤0.39 Concluiuse Concluiu se COVID19, 19, COVID1 1 COVID-1 20 r≥0.7 r07 7 (r≥0.7 r=0,8 r08 8 (r=0,8 p=<0,00 p000 00 r≥0.40≤0.6 r04006 4 6 (r≥0.40≤0.6 r=0,4 r04 (r=0,4 r≤0.3 r03 3 (r≤0.3 COVID- 2 r≥0. r0 (r≥0. r=0, (r=0, p=<0,0 p00 r≥0.40≤0. r0400 (r≥0.40≤0. r≤0. (r≤0. r≥0 (r≥0 r=0 (r=0 p=<0, p0 r≥0.40≤0 (r≥0.40≤0 r≤0 (r≤0 r≥ (r≥ r= (r= p=<0 r≥0.40≤ (r≥0.40≤ r≤ (r≤ (r p=< r≥0.40 (r≥0.40 p= r≥0.4 (r≥0.4

Abstract This article investigates the correlation between work engagement and work-related quality of life among nursing staff at a public hospital in São Paulo State, at the onset of the COVID-19 pandemic. A descriptive, correlational, cross-sectional study of nursing personnel was conducted from December 2020 to January 2021, using the Brazilian versions of the Work & Well-being Survey (Utrecht Work Engagement Scale - UWES) and the Work-related Quality of Life (WRQoL) scale, following Walton’s model. Nursing staffs returned a strong positive correlation (r≥0.70) between the social integration domain of the WRQoL and the vigour dimension of the UWES (r=0.88; p=<0.001); a moderate positive correlation (r≥0.40≤0.69) between working conditions (WRQOL) and the vigour (r=0.40; p<0.001), dedication (r=0.40; p<0.001) and overall score (r=0.41; p<0.001) dimensions of the UWES. Correlations were positive and weak (r≤0.39) for the other WRQoL domains and the UWES dimensions. It was concluded that personnel with satisfactory levels of quality of life tend to show higher levels of engagement at work. At the onset of the COVID-19 pandemic, nursing professionals were strongly engaged and satisfied with their work-related quality of life. workrelated related State COVID19 COVID 19 COVID-1 pandemic descriptive correlational crosssectional cross sectional 202 2021 Wellbeing Well being Utrecht Workrelated (WRQoL scale Waltons Walton s model r≥0.70 r070 r 0 70 (r≥0.70 r=0.88 r088 88 (r=0.88 p=<0.001 p0001 p 001 p=<0.001) r≥0.40≤0.69 r040069 40 69 (r≥0.40≤0.69 WRQOL (WRQOL r=0.40 r040 (r=0.40 p<0.001, p<0.001 , r=0.41 r041 41 (r=0.41 r≤0.39 r039 39 (r≤0.39 COVID1 1 COVID- 20 r≥0.7 r07 7 (r≥0.7 r=0.8 r08 8 (r=0.8 p=<0.00 p000 00 r≥0.40≤0.6 r04006 4 6 (r≥0.40≤0.6 r=0.4 r04 (r=0.4 p<0.00 r≤0.3 r03 3 (r≤0.3 2 r≥0. r0 (r≥0. r=0. (r=0. p=<0.0 p00 r≥0.40≤0. r0400 (r≥0.40≤0. p<0.0 r≤0. (r≤0. r≥0 (r≥0 r=0 (r=0 p=<0. p0 r≥0.40≤0 (r≥0.40≤0 p<0. r≤0 (r≤0 r≥ (r≥ r= (r= p=<0 r≥0.40≤ (r≥0.40≤ p<0 r≤ (r≤ (r p=< r≥0.40 (r≥0.40 p< p= r≥0.4 (r≥0.4

Resumo A pesquisa tem por objetivo descrever o perfil sociodemográfico e de saúde dos profissionais de enfermagem no contexto da pandemia da COVID-19 e propõe uma análise reflexiva sobre a essencialidade da categoria frente às demandas intrínsecas dos pacientes e do sistema de saúde brasileiro, especialmente, no contexto da emergência de saúde pública deflagrada pelo avanço exponencial do vírus SARS-CoV-2. O estudo revela a relação entre as injustiças históricas e os diferentes tipos de desigualdade que afetam e causam a vulnerabilidade da profissão, com fulcro na apresentação de potenciais perspectivas decorrentes desse processo histórico e dos acontecimentos recentes.

Abstract The present study aims to describe the sociodemographic and health profile of nursing professionals in the context of the COVID-19 pandemic and propose a reflective analysis on the essentiality of the category facing the intrinsic demands of patients and the Brazilian health system, especially in the context of the public health emergency triggered by the exponential advance of the SARS-CoV-2 virus. This study reveals the relationship between historical injustices and the different types of inequality that impacted and caused the vulnerability of the profession, with an emphasis on the presentation of potential perspectives arising from this historical process and recent events.

Resumo O artigo analisou o processo de precarização das relações de trabalho no setor da saúde, demonstrando como essa situação gerou sofrimento dos trabalhadores. O texto buscou registrar como a adoção institucional das concepções econômicas neoliberais, de redução das políticas sociais de Estado, acopladas a um histórico de rejeição cultural aos direitos trabalhistas, proporcionou a atração dos mecanismos de precarização do trabalho, notadamente, a terceirização da mão de obra e da prestação de serviços. No segundo momento, o texto aponta as impropriedades jurídicas cometidas, apresentando as consequências da fragilização do vínculo jurídico nas condições de trabalho desses trabalhadores, principalmente no que se refere às jornadas de trabalho e a remuneração, destacando-se, também, o quanto a disseminação desses vínculos representou um fator de rebaixamento geral dos salários e direitos trabalhistas e previdenciários no setor. Foram apresentados, ainda, dados das pesquisas da Fiocruz sobre condições de trabalho durante a pandemia. Conclui mostrando a urgência de se resgatarem os institutos jurídicos trabalhistas que foram abandonados no percurso histórico estudado, para direcionar a novo rumo as políticas públicas na saúde.

Abstract The present article analyzed the process of precarious work relations in the health sector, demonstrating how this situation generated illness and suffering among workers. The text sought to register how the institutional adoption of neoliberal economic conceptions, of the reduction of State social policies, coupled with a history of cultural rejection of labor rights, provided the attraction of mechanisms of precarious work for the public sector, notably, the outsourcing of labor and the provision of services. In a second moment, the text points out the legal improprieties committed, presenting the consequences of the weakening of the legal bond in the working conditions of these workers, mainly regarding working hours and remuneration, also highlighting how much the dissemination of these links represented a factor of a general reduction in wages and labor and social security rights in the sector. Data from Fiocruz surveys on working conditions during the pandemic were also presented. The article concludes by showing the urgency of rescuing the legal labor institutes that were abandoned in the historical path studied in order to guide the public health policies in a new direction.

Resumo O artigo investiga a correlação entre engajamento e qualidade de vida no trabalho dos profissionais de enfermagem de um hospital público do interior do estado de São Paulo, no início da pandemia de COVID-19. Estudo transversal, descritivo e correlacional, com profissionais de enfermagem, realizado entre dezembro de 2020 e janeiro de 2021. Foram utilizadas as versões brasileiras da Utrecht Work Engagement Scale (UWES) e da Escala de Avaliação da Qualidade de Vida no Trabalho (QVT), segundo modelo de Walton. Os profissionais de enfermagem apresentaram correlação forte e positiva (r≥0.70) entre o domínio integração social da QVT e a dimensão vigor da UWES (r=0,88; p=<0,001); correlação positiva moderada (r≥0.40≤0.69) entre as condições de trabalho (QVT) e as dimensões vigor (r=0,40; p=<0,001), dedicação (r=0,40; p=<0,001) e escore geral (r=0,41; p=<0,001) da UWES. As correlações foram positivas e fracas (r≤0.39) para os demais domínios da QVT e as dimensões da UWES. Concluiu-se que os profissionais com níveis satisfatórios de qualidade de vida tendem a ter níveis mais altos de engajamento no trabalho. No início da pandemia de COVID-19, os profissionais de enfermagem estavam fortemente engajados e satisfeitos com sua qualidade de vida no trabalho.

Abstract This article investigates the correlation between work engagement and work-related quality of life among nursing staff at a public hospital in São Paulo State, at the onset of the COVID-19 pandemic. A descriptive, correlational, cross-sectional study of nursing personnel was conducted from December 2020 to January 2021, using the Brazilian versions of the Work & Well-being Survey (Utrecht Work Engagement Scale - UWES) and the Work-related Quality of Life (WRQoL) scale, following Walton’s model. Nursing staffs returned a strong positive correlation (r≥0.70) between the social integration domain of the WRQoL and the vigour dimension of the UWES (r=0.88; p=<0.001); a moderate positive correlation (r≥0.40≤0.69) between working conditions (WRQOL) and the vigour (r=0.40; p<0.001), dedication (r=0.40; p<0.001) and overall score (r=0.41; p<0.001) dimensions of the UWES. Correlations were positive and weak (r≤0.39) for the other WRQoL domains and the UWES dimensions. It was concluded that personnel with satisfactory levels of quality of life tend to show higher levels of engagement at work. At the onset of the COVID-19 pandemic, nursing professionals were strongly engaged and satisfied with their work-related quality of life.

Resumen Los estudios sobre Ia juventud han cobrado mayor relevancia en el ámbito académico en los últimos anos, ampliando Ias posibilidades de análisis de esta categoría, consolidando la idea de Ia juventud como actor político y social. Esta expansión de los estudios ha puesto de manifiesto Ia heterogeneidad de Ia juventud, fomentando Ia investigación sobre los distintos aspectos de Ia misma. Los jóvenes rurales forman parte de la diversidad de actores sociales que conforman Ia juventud, y el estudio de sus dinámicas y fenómenos sociales ha sido una necesidad emergente. En este sentido, este artículo busca analizar a Ia juventud rural bajo el concepto de poder simbólico (BOURDIEU, 1989), en un intento por comprender como las relaciones de poder y dominación simbólica están presentes en la vida de los jóvenes de Bebida Velha, una comunidad rural tradicional ubicada en Pureza, RN. Utilizamos como metodologia de análisis el Discurso del Sujeto Colectivo, que consiste en una técnica con sesgo cualitativo y/o cuantitativo que propone construir un discurso colectivo a partir de los discursos individuals de un mismo grupo social. A partir del análisis del Discurso del Sujeto Colectivo de forma cualitativa, construído a través de 15 entrevistas semiestructuradas realizadas a jóvenes rurales, nos damos cuenta de que los principales espacios de socialización de los jóvenes rurales (educación, trabajo, familia y grupos de ocio) pueden ser reproductores de relaciones simbólicas de poder y dominación, a la vez que representan espacios de sociabilidad y oportunidades de cambio social. anos categoría social misma emergente sentido BOURDIEU, BOURDIEU (BOURDIEU 1989, 1989 , 1989) Velha Pureza RN yo o cualitativa 1 educación, educación (educación trabajo ocio 198 19

Resumo Os estudos acerca da juventude ganharam maior relevância na academia nos últimos anos, ampliando as possibilidades de análise dessa categoria, consolidando a ideia do jovem como ator político e social. Essa ampliação de estudos destacou a heterogeneidade do jovem, fomentando pesquisas sobre os diversos aspectos das juventudes. A juventude rural faz parte da diversidade de atores sociais que compõem as juventudes, e estudar suas dinâmicas e fenômenos sociais têm sido uma necessidade emergente. Nesse sentido, este artigo busca analisar a juventude rural sob o conceito de poder simbólico (BOURDIEU, 1989), na tentativa de compreender como as relações de poder e dominação simbólica estão presentes na vida dos jovens de Bebida Velha, comunidade rural tradicional localizada em Pureza, RN. Utilizamos como metodologia analítica o Discurso do Sujeito Coletivo, que consiste numa técnica com viés qualitativo e/ou quantitativo que se propõe a construir um discurso coletivo com base em discursos individuais de um mesmo grupo social. A partir da análise do Discurso do Sujeito Coletivo de maneira qualitativa, construído por meio de 15 entrevistas semiestruturadas realizadas com os jovens rurais, percebemos que os principais espaços de socialização da juventude rural (educação, trabalho, família e grupos de lazer) podem ser reprodutores das relações simbólicas de poder e dominação, ao mesmo tempo que representam espaços de sociabilidade e oportunidades de mudança social. anos categoria social juventudes emergente sentido BOURDIEU, BOURDIEU (BOURDIEU 1989, 1989 , 1989) Velha Pureza RN eou ou qualitativa 1 rurais educação, educação (educação trabalho lazer 198 19

Abstract Studies about youth have gained greater relevance in academia in recent years, expanding the possibilities of analysis of this category, consolidating the idea of youth as a political and social actor. This expansion of studies has highlighted the heterogeneity of young people, fostering research on the various aspects of youth. Rural youth are part of the diversity of social actors that make up the youth, and studying their dynamics and social phenomena has been an emerging need. In this sense, this article seeks to analyze rural youth underthe concept of symbolic power (BOURDIEU, 1989), in an attempt to understand how power relations and symbolic domination are present in the lives of young people from Bebida Velha, a traditional rural community located in Pureza, RN. We used as analytical methodology the Discourse of the Collective Subject, which is a technique with qualitative and/or quantitative bias that aims to build a collective discourse based on individual speeches of the same social group. From the analysis of the Discourse of the Collective Subject in a qualitative way, built through 15 semi-structured interviews conducted with rural youth, we realize that the main spaces of socialization of rural youth (education, work, family, and leisure groups) can be reproducers of symbolic relations of power and domination, while representing spaces of sociability and opportunities for social change. years category actor need sense BOURDIEU, BOURDIEU (BOURDIEU 1989, 1989 , 1989) Velha Pureza RN andor or group way 1 semistructured semi structured education, education (education work family groups change 198 19

ABSTRACT Objective The establishment of reference values for a subset of leukocytes is common in clinical practice, and ethnic variations are strongly associated with disease development. In Brazil, indigenous people are vulnerable to infections, and few studies have described the health and disease conditions of this population. This study aimed to provide reference values for immunological cell subsets in indigenous Brazilians living in the state of Mato Grosso do Sul. Methods Flow cytometry and 4-color combinations of monoclonal antibodies were used to characterize cells. A total of 115 healthy adults, mostly females (72%), were included in the study. The results are presented as mean and median (2.5%-97.5% percentiles) for T and B lymphocytes, CD4+ T cells, CD8+ T cells, Natural Killer cells, monocytes, and dendritic cells, providing an average immunological profile for the population in question. Results The relative medians of CD3+, CD4+, and CD8+ T cells were significantly higher in women than in men in a healthy indigenous population. Conclusion To our knowledge, cell reference data from indigenous Brazilians are unknown in the literature. The immune cell results presented in this pioneering study will contribute to the clinical and laboratory evaluation of the Brazilian indigenous population, especially given the important differences when compared with other Brazilian ethnic groups. practice development Brazil infections Sul 4color color 4 11 adults 72%, 72 72% , (72%) 2.5%97.5% 25975 2.5% 97.5% 2 5 97 (2.5%-97.5 percentiles lymphocytes CD4 CD CD8 monocytes question CD3 CD3+ knowledge literature groups 1 7 (72% 2.5%97.5 2597 25 2.5 975 97.5 9 (2.5%-97. (72 2.5%97. 259 2. 97. (2.5%-97 (7 2.5%97 (2.5%-9 ( 2.5%9 (2.5%- (2.5% (2.5 (2. (2

Abstract The pathogenesis of systemic lupus erythematosus (SLE) is complex. Few studies in Brazilian population have addressed cell phenotypes associated with immunological responses and their associations with SLE activity. The aim of this study is to investigate cell phenotypes associated to SLE diagnosis, treatment and activity. Twenty-eight SLE female patients (17 inactive, 11 active) and 10 healthy women were included in this study. Markers of natural killer (Nk), T and B cells in peripheral blood were evaluated by flow cytometry. Nkt cells were decreased only in SLE active patients. Activated CD4+, regulatory T FoxP3+ and B cells were decreased in both active and inactive SLE patients, compared to control group. The data corroborate the disruption of immune regulatory response in SLE patients and suggest phenotipic changes as possible biomarkers of SLE activity. (SLE complex activity diagnosis Twentyeight Twenty eight 17 (1 1 Nk, Nk , (Nk) cytometry CD4 CD CD4+ FoxP3 FoxP group ( (Nk