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1.
PASSIVE-SAMPLER EMPLOYED FOR ANTIFOULING BOOSTER BIOCIDES ANALYSES IN SEAWATER PASSIVESAMPLER PASSIVE SAMPLER
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Freitas, Marta S. D.
; Batista, Rodrigo M.
; Costa, Andressa R. C.
; Amarante Junior, Ozelito P. de
; Franco, Teresa C. R. S.
; Fillmann, Gilberto
; Brito, Natilene M.
.
The antifouling booster biocides are frequently studied for toxic effects on the aquatic ecosystems. The present investigation proposes passive silicone rubber samplers as a collection method for biocides, once these methods can concentrate substances in aqueous matrices at very low levels. Through the passive sampler-water partition coefficient (Ksw) and the analyte chemical nature, we can optimize their extraction from the membrane to apply in the sample medium. We used the co-solvent method to determine the Ksw of three third-generation antifouling biocides, chlorothalonil, dichlofluanid, and dichlorooctylisothiazolinone (DCOIT), with log Ksw = 2.24, 4.01, and 2.38, respectively. Improving extraction also led to a recovery range higher than 70%, determinations were carried out by gas chromatography with an electron capture detector. Biocides concentration in seawater samples from Itaqui port (São Marcos Bay, northern Brazil) ranged from 0.058 to 0.72 µg L-1 for chlorothalonil, 0.001 to 0.008 µg L-1 for dichlofluanid, and 0.018 to 0.64 µg L-1 for DCOIT. ecosystems levels samplerwater sampler water (Ksw nature medium cosolvent co solvent thirdgeneration third generation chlorothalonil dichlofluanid DCOIT, DCOIT , (DCOIT) 224 2 24 2.24 401 4 01 4.01 238 38 2.38 respectively 70 70% detector São Bay Brazil 0058 0 058 0.05 072 72 0.7 L1 L 1 L- 0001 001 0.00 0008 008 0018 018 0.01 064 64 0.6 (DCOIT 22 2.2 40 4.0 23 3 2.3 7 005 05 0.0 07 0. 000 00 06 6 2. 4.
2.
Evolución de la situación clínica en trasplante cardíaco: un análisis de la última década en Argentina
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Burgos, Lucrecia M.
; Vrancic, Juan M.
; Ballari, Franco N.
; Navia, Daniel O.
; Baro Vila, Rocío C.
; Espinoza, Juan C.
; de Bortoli, María A.
; Piccinini, Fernando
; Diez, Mirta
.
3.
Renal deficit and associated factors in children born with low birth weight
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Vale, Marynéa Silva do
; Marques, Patrícia Franco
; Cavalcante, Milady Cutrim Vieira
; Brito, Mateus Noleto
; Santos, Alcione Miranda dos
; Salgado-Filho, Natalino
; Duarte, José Luiz M. B.
.
ABSTRACT Introduction: Kidney problems may be due to low birth weight alone or may occur in association with other conditions. The objective this study was to evaluate the association between maternal and birth characteristics, anthropometric measurements, and kidney function deficit in low birth weight infants. Methods: Cross-sectional study with children who were born weighing < 2500 grams and were under outpatient follow-up. Maternal factors investigated were prenatal care and presence of hypertension, diabetes, and infection during pregnancy. The children’s variables were sex, gestational age, birth weight, Apgar score, use of nephrotoxic medications, age, body weight at the time of evaluation, height, and serum creatinine and cystatin C dosages. The glomerular filtration rate (GFR) was estimated with the combined Zapittelli equation. Multivariate logistic regression model was used for identification of associated factors, with renal function deficit (GFR < 60 mL/min/1.73 m2) as the dependent variable. Results: Of the 154 children evaluated, 34.42% had kidney function deficit. Most of them had a gestational age > 32 weeks (56.6%), a mean birth weight of 1439.7 grams, and mean estimated GFR of 46.9 ± 9.3 mL/min/1.73 m2. There was a significant association of GFR < 60 mL/min/1.73 m2 with children’s current weight and use of nephrotoxic drugs. Discussion: Children born with low birth weight had a high prevalence of kidney function deficit and current normal weight was a protective factor while the use of nephrotoxic drugs during perinatal period increased the chance of kidney deficit. These findings reinforce the need to evaluate the kidney function in these children, especially those who use nephrotoxic drugs. Introduction conditions characteristics measurements infants Methods Crosssectional Cross sectional 250 followup. followup follow up. up follow-up hypertension diabetes pregnancy childrens s sex score medications evaluation height dosages equation 6 mLmin173 mLmin mL min 1 73 mL/min/1.7 m variable Results 15 evaluated 3442 34 42 34.42 3 56.6%, 566 56.6% , 56 (56.6%) 14397 1439 7 1439. 469 46 9 46. 93 9. Discussion 25 mLmin17 mL/min/1. 344 4 34.4 56.6 5 (56.6% 143 2 mLmin1 mL/min/1 34. 56. (56.6 14 mL/min/ (56. mL/min (56 (5 (
RESUMO Introdução: Problemas renais podem ser devido apenas ao baixo peso ao nascer ou podem ocorrer em associação com outras condições. O objetivo deste estudo foi avaliar a associação entre características maternas e de nascimento, medidas antropométricas e déficit da função renal em bebês de baixo peso ao nascer. Métodos: Estudo transversal com crianças que nasceram com peso < 2500 gramas e estavam sob acompanhamento ambulatorial. Os fatores maternos investigados foram cuidados pré-natal e presença de hipertensão, diabetes e infecção durante a gravidez. As variáveis das crianças foram sexo, idade gestacional, peso ao nascer, índice Apgar, uso de medicamentos nefrotóxicos, idade, peso corporal no momento da avaliação, altura e dosagens séricas de creatinina e cistatina C. A taxa de filtração glomerular (TFG) foi estimada com a equação combinada de Zapittelli. Utilizou-se um modelo de regressão logística multivariada para identificação de fatores associados, com déficit da função renal (TFG < 60 mL/min/1,73 m2) como variável dependente. Resultados: Das 154 crianças avaliadas, 34,42% apresentaram déficit da função renal. A maioria tinha idade gestacional > 32 semanas (56,6%), peso médio ao nascer de 1439,7 gramas, e TFG média estimada de 46,9 ± 9,3 mL/min/1,73 m2. Houve uma associação significativa da TFG < 60 mL/min/1,73 m2 com o peso atual das crianças e o uso de medicamentos nefrotóxicos. Discussão: Crianças nascidas com baixo peso apresentaram alta prevalência de déficit da função renal e o peso atual normal foi um fator de proteção, enquanto o uso de medicamentos nefrotóxicos durante o período perinatal aumentou a chance de déficit renal. Estes achados reforçam a necessidade de avaliar a função renal destas crianças, especialmente aquelas que usam medicamentos nefrotóxicos. Introdução condições nascimento Métodos 250 ambulatorial prénatal pré natal hipertensão gravidez sexo Apgar avaliação C Zapittelli Utilizouse Utilizou se associados 6 mLmin173 mLmin mL min 1 73 mL/min/1,7 m dependente Resultados 15 avaliadas 3442 34 42 34,42 3 56,6%, 566 56,6% , 56 (56,6%) 14397 1439 7 1439, 469 46 9 46, 93 9, Discussão proteção 25 mLmin17 mL/min/1, 344 4 34,4 56,6 5 (56,6% 143 2 mLmin1 mL/min/1 34, 56, (56,6 14 mL/min/ (56, mL/min (56 (5 (
4.
Chemical and mineral composition of the raw and cooked immature grains of cowpea genotypes
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Gomes, Fernanda de O.
; Silva, Izabel C. V.
; Franco, Luis J. D.
; Hashimoto, Jorge M.
; Damasceno-Silva, Kaesel J.
; Rocha, Maurisrael de M.
.
ABSTRACT Immature cowpea grains are a rich source of proteins, minerals, dietary fiber, and phenolic compounds and also have a high antioxidant capacity compared to dry grains. Its consumption promotes a healthy and diversified diet. The objective of this work was to evaluate the cooking time and chemical and mineral composition of the raw and cooked immature grains of different cowpea genotypes. Four genotypes, two elite lines (MNC00-595F-27 and MNC05-847B-123) and two commercial cultivars (BRSTumucumaque and Vagem Roxa-THE) were analyzed. Cooking time was evaluated using the Mattson cooker. Proximate composition and minerals were determined. A completely randomized design with three replications in factorial scheme 1 (genotype) × 2 (raw and cooked grains) was adopted, except for cooking quality. The genotypes MNC05-847B-123 and BRS-Tumucumaque differed from the other genotypes, presenting faster cooking of the immature grain. Cooking increased the moisture content and reduced ash, lipid, protein, and carbohydrates contents and total energy value. The lines MNC05-847B-123 and MNC00-595F-27 showed higher contents of the nutrients of the centesimal composition after cooking than the local cultivar Vagem Roxa-THE, except for the moisture content. The mineral content decreased after cooking, with Fe, Zn, and Mn contents having the least losses with thermal processing. The lines MNC05-847B-123 and MNC00-595F-27, even with losses after the thermal processing of the immature grain, have nutritional potential as cultivars for the green-bean market. proteins fiber diet MNC00595F27 MNCF MNC00 595F 27 MNC F (MNC00-595F-2 MNC05847B123 MNCB MNC05 847B 123 B BRSTumucumaque RoxaTHE Roxa THE Roxa-THE analyzed cooker determined genotype (genotype adopted quality MNC05-847B-12 BRS Tumucumaque grain ash lipid protein value MNC00-595F-2 RoxaTHE, THE, Fe Zn MNC00595F27, 27, greenbean green bean market MNC00595F2 MNC0 (MNC00-595F- MNC05847B12 12 MNC05-847B-1 MNC00-595F- MNC00595F (MNC00-595F MNC05847B1 MNC05-847B- MNC00-595F MNC05847B MNC05-847B
RESUMO Os grãos imaturos de feijão-caupi são uma rica fonte de proteínas, minerais, fibra alimentar e compostos fenólicos e também possuem alta capacidade antioxidante em comparação aos grãos secos. O seu consumo promove uma alimentação saudável e diversificada. O objetivo deste trabalho foi avaliar o tempo de cozimento e a composição química e mineral de grãos imaturos crus e cozidos de diferentes genótipos de feijão-caupi. Foram analisados quatro genótipos, duas linhagens elite (MNC00-595F-27 e MNC05847B-123) e duas cultivares comerciais (BRS-Tumucumaque e Vagem Roxa-THE). O tempo de cozimento foi avaliado utilizando-se o cozedor de Mattson. Foram determinados a composição centesimal e minerais. Adotou-se o delineamento inteiramente casualizado com três repetições em esquema fatorial 1 (genótipo) × 2 (grãos crus e cozidos), exceto para qualidade de cozimento. Os genótipos MNC05847B-123 e BRS-Tumucumaque diferiram dos demais genótipos, apresentando cozimento mais rápido do grão imaturo. O cozimento aumentou o teor de umidade e reduziu o teor de cinzas, lipídios, proteínas e carboidratos e o valor energético total. As linhagens MNC05-847B-123 e MNC00-595F-27 apresentaram teores de nutrientes da composição centesimal mais altos após o cozimento que a cultivar local Vagem Roxa-THE, exceto para o teor de umidade. O teor de minerais diminuiu após o cozimento, sendo que os teores de Fe, Zn e Mn tiveram as menores perdas com o processamento térmico. As linhagens MNC05-847B-123 e MNC00595F-27, mesmo com perdas após o processamento térmico do grão imaturo, apresentam potencial nutricional como cultivares para o mercado de feijão verde. feijãocaupi caupi secos diversificada feijãocaupi. caupi. MNC00595F27 MNCF MNC00 595F 27 MNC F (MNC00-595F-2 MNC05847B123 MNCB MNC05847B 123 B BRSTumucumaque BRS Tumucumaque RoxaTHE. RoxaTHE Roxa THE . Roxa-THE) utilizandose utilizando se Mattson Adotouse Adotou genótipo (genótipo cozidos, , cozidos) MNC05847B-12 imaturo cinzas lipídios total MNC05 847B MNC05-847B-12 MNC00-595F-2 RoxaTHE, THE, Roxa-THE Fe MNC00595F27, MNC00595F 27, MNC00595F-27 verde MNC00595F2 MNC0 (MNC00-595F- MNC05847B12 12 MNC05847B-1 MNC05-847B-1 MNC00-595F- MNC00595F-2 (MNC00-595F MNC05847B1 MNC05847B- MNC05-847B- MNC00-595F MNC00595F- MNC05-847B
5.
Bioactive Amino-Quinazolines: Synthesis and Therapeutic Applications AminoQuinazolines Amino Quinazolines Amino-Quinazolines
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Journal of the Brazilian Chemical Society
- Métricas do periódico
The amino-quinazoline scaffold stands out as a privileged structure in Medicinal Chemistry, due to its pleiotropic pharmacological profile. It has been explored in the design and development of novel drug candidates for several therapeutic applications, including antihypertensive, anti-inflammatory, antipsychotic, anti-Alzheimer, anticancer, antiviral, antibiotic, and antiparasitic treatments, among others. The therapeutic value of amino-quinazoline drugs was first demonstrated with the use of alpha 1-adrenoceptor antagonists, such as prazosin, doxazosin and terazosin. These drugs were initially approved for the treatment of hypertension and later for the treatment of benign prostatic hyperplasia. Several amino-quinazoline kinase inhibitors were introduced into the clinic as innovative therapeutic alternatives for cancer treatment after the U.S. Food and Drug Administration approved gefitinib in 2003 as a novel epidermal growth factor receptor inhibitor drug for non-small cell lung cancer. More recently, in 2021, the kinase inhibitor belumosudil was launched as a third-line therapy for adult and pediatric patients with chronic graft-versus-host disease. This article reviews the synthetic preparation methods and pharmacological activities of bioactive amino-quinazolines described in recent decades. aminoquinazoline amino quinazoline Chemistry profile applications antihypertensive antiinflammatory, antiinflammatory anti inflammatory, inflammatory anti-inflammatory antipsychotic antiAlzheimer, antiAlzheimer Alzheimer, Alzheimer anti-Alzheimer anticancer antiviral antibiotic treatments others 1adrenoceptor adrenoceptor 1 antagonists prazosin terazosin hyperplasia US U S U.S 200 nonsmall non small recently 2021 thirdline third line graftversushost graft versus host disease aminoquinazolines quinazolines decades 20 202 2
6.
Diclofenac sodium adsorption on activated carbon: experimental, modeling and bayesian statistics carbon experimental
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DIAS, CAMILA S.
; FRANCO, MARCELA ANDREA E.
; RODRIGUES, EMERSON C.
; FERREIRA, JOSIEL L.
; VIEGAS, BRUNO M.
; FÉRIS, LILIANA A.
; ESTUMANO, DIEGO C.
; MACÊDO, EMANUEL N.
.
Anais da Academia Brasileira de Ciências
- Métricas do periódico
Abstract The present study modeled the adsorption process of the drug diclofenac sodium on activated charcoal. For this purpose, a mass balance-based model was used considering a fixed bed column. The mass transfer rate in the solid phase was represented by a driving force model proposed in this study, and a gamma exponent with a range of 0 > γ ≤ 2 was assigned to the model. Different isotherms were adopted to represent the equilibrium at the solid/liquid interface: the Langmuir, Freundlich, Sips and Redlich-Peterson isotherms. The modeling was approached from the perspective of Bayesian statistics, and the Markov chain Monte Carlo method was used for parameter estimation. Model validation was performed with experimental data obtained under different operating conditions of initial concentration ($C_{0 charcoal purpose balancebased balance based column solidliquid liquid interface Langmuir Freundlich RedlichPeterson Redlich Peterson statistics estimation $C_0 C0 C $C_ ($C_{ $C ($C_ ($C
7.
Catálogo Taxonômico da Fauna do Brasil: Setting the baseline knowledge on the animal diversity in Brazil Brasil
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Boeger, Walter A.
; Valim, Michel P.
; Zaher, Hussam
; Rafael, José A.
; Forzza, Rafaela C.
; Percequillo, Alexandre R.
; Serejo, Cristiana S.
; Garraffoni, André R.S.
; Santos, Adalberto J.
; Slipinski, Adam
; Linzmeier, Adelita M.
; Calor, Adolfo R.
; Garda, Adrian A.
; Kury, Adriano B.
; Fernandes, Agatha C.S.
; Agudo-Padrón, Aisur I.
; Akama, Alberto
; Silva Neto, Alberto M. da
; Burbano, Alejandro L.
; Menezes, Aleksandra
; Pereira-Colavite, Alessandre
; Anichtchenko, Alexander
; Lees, Alexander C.
; Bezerra, Alexandra M.R.
; Domahovski, Alexandre C.
; Pimenta, Alexandre D.
; Aleixo, Alexandre L.P.
; Marceniuk, Alexandre P.
; Paula, Alexandre S. de
; Somavilla, Alexandre
; Specht, Alexandre
; Camargo, Alexssandro
; Newton, Alfred F.
; Silva, Aline A.S. da
; Santos, Aline B. dos
; Tassi, Aline D.
; Aragão, Allan C.
; Santos, Allan P.M.
; Migotto, Alvaro E.
; Mendes, Amanda C.
; Cunha, Amanda
; Chagas Júnior, Amazonas
; Sousa, Ana A.T. de
; Pavan, Ana C.
; Almeida, Ana C.S.
; Peronti, Ana L.B.G.
; Henriques-Oliveira, Ana L.
; Prudente, Ana L.
; Tourinho, Ana L.
; Pes, Ana M.O.
; Carmignotto, Ana P.
; Wengrat, Ana P.G. da Silva
; Dornellas, Ana P.S.
; Molin, Anamaria Dal
; Puker, Anderson
; Morandini, André C.
; Ferreira, André da S.
; Martins, André L.
; Esteves, André M.
; Fernandes, André S.
; Roza, André S.
; Köhler, Andreas
; Paladini, Andressa
; Andrade, Andrey J. de
; Pinto, Ângelo P.
; Salles, Anna C. de A.
; Gondim, Anne I.
; Amaral, Antonia C.Z.
; Rondón, Antonio A.A.
; Brescovit, Antonio
; Lofego, Antônio C.
; Marques, Antonio C.
; Macedo, Antonio
; Andriolo, Artur
; Henriques, Augusto L.
; Ferreira Júnior, Augusto L.
; Lima, Aurino F. de
; Barros, Ávyla R. de A.
; Brito, Ayrton do R.
; Romera, Bárbara L.V.
; Vasconcelos, Beatriz M.C. de
; Frable, Benjamin W.
; Santos, Bernardo F.
; Ferraz, Bernardo R.
; Rosa, Brunno B.
; Sampaio, Brunno H.L.
; Bellini, Bruno C.
; Clarkson, Bruno
; Oliveira, Bruno G. de
; Corrêa, Caio C.D.
; Martins, Caleb C.
; Castro-Guedes, Camila F. de
; Souto, Camilla
; Bicho, Carla de L.
; Cunha, Carlo M.
; Barboza, Carlos A. de M.
; Lucena, Carlos A.S. de
; Barreto, Carlos
; Santana, Carlos D.C.M. de
; Agne, Carlos E.Q.
; Mielke, Carlos G.C.
; Caetano, Carlos H.S.
; Flechtmann, Carlos H.W.
; Lamas, Carlos J.E.
; Rocha, Carlos
; Mascarenhas, Carolina S.
; Margaría, Cecilia B.
; Waichert, Cecilia
; Digiani, Celina
; Haddad, Célio F.B.
; Azevedo, Celso O.
; Benetti, Cesar J.
; Santos, Charles M.D. dos
; Bartlett, Charles R.
; Bonvicino, Cibele
; Ribeiro-Costa, Cibele S.
; Santos, Cinthya S.G.
; Justino, Cíntia E.L.
; Canedo, Clarissa
; Bonecker, Claudia C.
; Santos, Cláudia P.
; Carvalho, Claudio J.B. de
; Gonçalves, Clayton C.
; Galvão, Cleber
; Costa, Cleide
; Oliveira, Cléo D.C. de
; Schwertner, Cristiano F.
; Andrade, Cristiano L.
; Pereira, Cristiano M.
; Sampaio, Cristiano
; Dias, Cristina de O.
; Lucena, Daercio A. de A.
; Manfio, Daiara
; Amorim, Dalton de S.
; Queiroz, Dalva L. de
; Queiroz, Dalva L. de
; Colpani, Daniara
; Abbate, Daniel
; Aquino, Daniel A.
; Burckhardt, Daniel
; Cavallari, Daniel C.
; Prado, Daniel de C. Schelesky
; Praciano, Daniel L.
; Basílio, Daniel S.
; Bená, Daniela de C.
; Toledo, Daniela G.P. de
; Takiya, Daniela M.
; Fernandes, Daniell R.R.
; Ament, Danilo C.
; Cordeiro, Danilo P.
; Silva, Darliane E.
; Pollock, Darren A.
; Muniz, David B.
; Gibson, David I.
; Nogueira, David S.
; Marques, Dayse W.A.
; Lucatelli, Débora
; Garcia, Deivys M.A.
; Baêta, Délio
; Ferreira, Denise N.M.
; Rueda-Ramírez, Diana
; Fachin, Diego A.
; Souza, Diego de S.
; Rodrigues, Diego F.
; Pádua, Diego G. de
; Barbosa, Diego N.
; Dolibaina, Diego R.
; Amaral, Diogo C.
; Chandler, Donald S.
; Maccagnan, Douglas H.B.
; Caron, Edilson
; Carvalho, Edrielly
; Adriano, Edson A.
; Abreu Júnior, Edson F. de
; Pereira, Edson H.L.
; Viegas, Eduarda F.G.
; Carneiro, Eduardo
; Colley, Eduardo
; Eizirik, Eduardo
; Santos, Eduardo F. dos
; Shimbori, Eduardo M.
; Suárez-Morales, Eduardo
; Arruda, Eliane P. de
; Chiquito, Elisandra A.
; Lima, Élison F.B.
; Castro, Elizeu B. de
; Orlandin, Elton
; Nascimento, Elynton A. do
; Razzolini, Emanuel
; Gama, Emanuel R.R.
; Araujo, Enilma M. de
; Nishiyama, Eric Y.
; Spiessberger, Erich L.
; Santos, Érika C.L. dos
; Contreras, Eugenia F.
; Galati, Eunice A.B.
; Oliveira Junior, Evaldo C. de
; Gallardo, Fabiana
; Hernandes, Fabio A.
; Lansac-Tôha, Fábio A.
; Pitombo, Fabio B.
; Dario, Fabio Di
; Santos, Fábio L. dos
; Mauro, Fabio
; Nascimento, Fabio O. do
; Olmos, Fabio
; Amaral, Fabio R.
; Schunck, Fabio
; Godoi, Fábio S. P. de
; Machado, Fabrizio M.
; Barbo, Fausto E.
; Agrain, Federico A.
; Ribeiro, Felipe B.
; Moreira, Felipe F.F.
; Barbosa, Felipe F.
; Silva, Fenanda S.
; Cavalcanti, Fernanda F.
; Straube, Fernando C.
; Carbayo, Fernando
; Carvalho Filho, Fernando
; Zanella, Fernando C.V.
; Jacinavicius, Fernando de C.
; Farache, Fernando H.A.
; Leivas, Fernando
; Dias, Fernando M.S.
; Mantellato, Fernando
; Vaz-de-Mello, Fernando Z.
; Gudin, Filipe M.
; Albuquerque, Flávio
; Molina, Flavio B.
; Passos, Flávio D.
; Shockley, Floyd W.
; Pinheiro, Francielly F.
; Mello, Francisco de A.G. de
; Nascimento, Francisco E. de L.
; Franco, Francisco L.
; Oliveira, Francisco L. de
; Melo, Francisco T. de V.
; Quijano, Freddy R.B.
; Salles, Frederico F.
; Biffi, Gabriel
; Queiroz, Gabriel C.
; Bizarro, Gabriel L.
; Hrycyna, Gabriela
; Leviski, Gabriela
; Powell, Gareth S.
; Santos, Geane B. dos
; Morse, Geoffrey E.
; Brown, George
; Mattox, George M.T.
; Zimbrão, Geraldo
; Carvalho, Gervásio S.
; Miranda, Gil F.G.
; Moraes, Gilberto J. de
; Lourido, Gilcélia M.
; Neves, Gilmar P.
; Moreira, Gilson R.P.
; Montingelli, Giovanna G.
; Maurício, Giovanni N.
; Marconato, Gláucia
; Lopez, Guilherme E.L.
; Silva, Guilherme L. da
; Muricy, Guilherme
; Brito, Guilherme R.R.
; Garbino, Guilherme S.T.
; Flores, Gustavo E.
; Graciolli, Gustavo
; Libardi, Gustavo S.
; Proctor, Heather C.
; Gil-Santana, Helcio R.
; Varella, Henrique R.
; Escalona, Hermes E.
; Schmitz, Hermes J.
; Rodrigues, Higor D.D.
; Galvão Filho, Hilton de C.
; Quintino, Hingrid Y.S.
; Pinto, Hudson A.
; Rainho, Hugo L.
; Miyahira, Igor C.
; Gonçalves, Igor de S.
; Martins, Inês X.
; Cardoso, Irene A.
; Oliveira, Ismael B. de
; Franz, Ismael
; Fernandes, Itanna O.
; Golfetti, Ivan F.
; S. Campos-Filho, Ivanklin
; Oliveira, Ivo de S.
; Delabie, Jacques H.C.
; Oliveira, Jader de
; Prando, Jadila S.
; Patton, James L.
; Bitencourt, Jamille de A.
; Silva, Janaina M.
; Santos, Jandir C.
; Arruda, Janine O.
; Valderrama, Jefferson S.
; Dalapicolla, Jeronymo
; Oliveira, Jéssica P.
; Hájek, Jiri
; Morselli, João P.
; Narita, João P.
; Martin, João P.I.
; Grazia, Jocélia
; McHugh, Joe
; Cherem, Jorge J.
; Farias Júnior, José A.S.
; Fernandes, Jose A.M.
; Pacheco, José F.
; Birindelli, José L.O.
; Rezende, José M.
; Avendaño, Jose M.
; Duarte, José M. Barbanti
; Ribeiro, José R. Inácio
; Mermudes, José R.M.
; Pujol-Luz, José R.
; Santos, Josenilson R. dos
; Câmara, Josenir T.
; Teixeira, Joyce A.
; Prado, Joyce R. do
; Botero, Juan P.
; Almeida, Julia C.
; Kohler, Julia
; Gonçalves, Julia P.
; Beneti, Julia S.
; Donahue, Julian P.
; Alvim, Juliana
; Almeida, Juliana C.
; Segadilha, Juliana L.
; Wingert, Juliana M.
; Barbosa, Julianna F.
; Ferrer, Juliano
; Santos, Juliano F. dos
; Kuabara, Kamila M.D.
; Nascimento, Karine B.
; Schoeninger, Karine
; Campião, Karla M.
; Soares, Karla
; Zilch, Kássia
; Barão, Kim R.
; Teixeira, Larissa
; Sousa, Laura D. do N.M. de
; Dumas, Leandro L.
; Vieira, Leandro M.
; Azevedo, Leonardo H.G.
; Carvalho, Leonardo S.
; Souza, Leonardo S. de
; Rocha, Leonardo S.G.
; Bernardi, Leopoldo F.O.
; Vieira, Letícia M.
; Johann, Liana
; Salvatierra, Lidianne
; Oliveira, Livia de M.
; Loureiro, Lourdes M.A. El-moor
; Barreto, Luana B.
; Barros, Luana M.
; Lecci, Lucas
; Camargos, Lucas M. de
; Lima, Lucas R.C.
; Almeida, Lucia M.
; Martins, Luciana R.
; Marinoni, Luciane
; Moura, Luciano de A.
; Lima, Luciano
; Naka, Luciano N.
; Miranda, Lucília S.
; Salik, Lucy M.
; Bezerra, Luis E.A.
; Silveira, Luis F.
; Campos, Luiz A.
; Castro, Luiz A.S. de
; Pinho, Luiz C.
; Silveira, Luiz F.L.
; Iniesta, Luiz F.M.
; Tencatt, Luiz F.C.
; Simone, Luiz R.L.
; Malabarba, Luiz R.
; Cruz, Luiza S. da
; Sekerka, Lukas
; Barros, Lurdiana D.
; Santos, Luziany Q.
; Skoracki, Maciej
; Correia, Maira A.
; Uchoa, Manoel A.
; Andrade, Manuella F.G.
; Hermes, Marcel G.
; Miranda, Marcel S.
; Araújo, Marcel S. de
; Monné, Marcela L.
; Labruna, Marcelo B.
; Santis, Marcelo D. de
; Duarte, Marcelo
; Knoff, Marcelo
; Nogueira, Marcelo
; Britto, Marcelo R. de
; Melo, Marcelo R.S. de
; Carvalho, Marcelo R. de
; Tavares, Marcelo T.
; Kitahara, Marcelo V.
; Justo, Marcia C.N.
; Botelho, Marcia J.C.
; Couri, Márcia S.
; Borges-Martins, Márcio
; Felix, Márcio
; Oliveira, Marcio L. de
; Bologna, Marco A.
; Gottschalk, Marco S.
; Tavares, Marcos D.S.
; Lhano, Marcos G.
; Bevilaqua, Marcus
; Santos, Marcus T.T.
; Domingues, Marcus V.
; Sallum, Maria A.M.
; Digiani, María C.
; Santarém, Maria C.A.
; Nascimento, Maria C. do
; Becerril, María de los A.M.
; Santos, Maria E.A. dos
; Passos, Maria I. da S. dos
; Felippe-Bauer, Maria L.
; Cherman, Mariana A.
; Terossi, Mariana
; Bartz, Marie L.C.
; Barbosa, Marina F. de C.
; Loeb, Marina V.
; Cohn-Haft, Mario
; Cupello, Mario
; Martins, Marlúcia B.
; Christofersen, Martin L.
; Bento, Matheus
; Rocha, Matheus dos S.
; Martins, Maurício L.
; Segura, Melissa O.
; Cardenas, Melissa Q.
; Duarte, Mércia E.
; Ivie, Michael A.
; Mincarone, Michael M.
; Borges, Michela
; Monné, Miguel A.
; Casagrande, Mirna M.
; Fernandez, Monica A.
; Piovesan, Mônica
; Menezes, Naércio A.
; Benaim, Natalia P.
; Reategui, Natália S.
; Pedro, Natan C.
; Pecly, Nathalia H.
; Ferreira Júnior, Nelson
; Silva Júnior, Nelson J. da
; Perioto, Nelson W.
; Hamada, Neusa
; Degallier, Nicolas
; Chao, Ning L.
; Ferla, Noeli J.
; Mielke, Olaf H.H.
; Evangelista, Olivia
; Shibatta, Oscar A.
; Oliveira, Otto M.P.
; Albornoz, Pablo C.L.
; Dellapé, Pablo M.
; Gonçalves, Pablo R.
; Shimabukuro, Paloma H.F.
; Grossi, Paschoal
; Rodrigues, Patrícia E. da S.
; Lima, Patricia O.V.
; Velazco, Paul
; Santos, Paula B. dos
; Araújo, Paula B.
; Silva, Paula K.R.
; Riccardi, Paula R.
; Garcia, Paulo C. de A.
; Passos, Paulo G.H.
; Corgosinho, Paulo H.C.
; Lucinda, Paulo
; Costa, Paulo M.S.
; Alves, Paulo P.
; Roth, Paulo R. de O.
; Coelho, Paulo R.S.
; Duarte, Paulo R.M.
; Carvalho, Pedro F. de
; Gnaspini, Pedro
; Souza-Dias, Pedro G.B.
; Linardi, Pedro M.
; Bartholomay, Pedro R.
; Demite, Peterson R.
; Bulirsch, Petr
; Boll, Piter K.
; Pereira, Rachel M.M.
; Silva, Rafael A.P.F.
; Moura, Rafael B. de
; Boldrini, Rafael
; Silva, Rafaela A. da
; Falaschi, Rafaela L.
; Cordeiro, Ralf T.S.
; Mello, Ramon J.C.L.
; Singer, Randal A.
; Querino, Ranyse B.
; Heleodoro, Raphael A.
; Castilho, Raphael de C.
; Constantino, Reginaldo
; Guedes, Reinaldo C.
; Carrenho, Renan
; Gomes, Renata S.
; Gregorin, Renato
; Machado, Renato J.P.
; Bérnils, Renato S.
; Capellari, Renato S.
; Silva, Ricardo B.
; Kawada, Ricardo
; Dias, Ricardo M.
; Siewert, Ricardo
; Brugnera, Ricaro
; Leschen, Richard A.B.
; Constantin, Robert
; Robbins, Robert
; Pinto, Roberta R.
; Reis, Roberto E. dos
; Ramos, Robson T. da C.
; Cavichioli, Rodney R.
; Barros, Rodolfo C. de
; Caires, Rodrigo A.
; Salvador, Rodrigo B.
; Marques, Rodrigo C.
; Araújo, Rodrigo C.
; Araujo, Rodrigo de O.
; Dios, Rodrigo de V.P.
; Johnsson, Rodrigo
; Feitosa, Rodrigo M.
; Hutchings, Roger W.
; Lara, Rogéria I.R.
; Rossi, Rogério V.
; Gerstmeier, Roland
; Ochoa, Ronald
; Hutchings, Rosa S.G.
; Ale-Rocha, Rosaly
; Rocha, Rosana M. da
; Tidon, Rosana
; Brito, Rosangela
; Pellens, Roseli
; Santos, Sabrina R. dos
; Santos, Sandra D. dos
; Paiva, Sandra V.
; Santos, Sandro
; Oliveira, Sarah S. de
; Costa, Sávio C.
; Gardner, Scott L.
; Leal, Sebastián A. Muñoz
; Aloquio, Sergio
; Bonecker, Sergio L.C.
; Bueno, Sergio L. de S.
; Almeida, Sérgio M. de
; Stampar, Sérgio N.
; Andena, Sérgio R.
; Posso, Sergio R.
; Lima, Sheila P.
; Gadelha, Sian de S.
; Thiengo, Silvana C.
; Cohen, Simone C.
; Brandão, Simone N.
; Rosa, Simone P.
; Ribeiro, Síria L.B.
; Letana, Sócrates D.
; Santos, Sonia B. dos
; Andrade, Sonia C.S.
; Dávila, Stephane
; Vaz, Stéphanie
; Peck, Stewart B.
; Christo, Susete W.
; Cunha, Suzan B.Z.
; Gomes, Suzete R.
; Duarte, Tácio
; Madeira-Ott, Taís
; Marques, Taísa
; Roell, Talita
; Lima, Tarcilla C. de
; Sepulveda, Tatiana A.
; Maria, Tatiana F.
; Ruschel, Tatiana P.
; Rodrigues, Thaiana
; Marinho, Thais A.
; Almeida, Thaís M. de
; Miranda, Thaís P.
; Freitas, Thales R.O.
; Pereira, Thalles P.L.
; Zacca, Thamara
; Pacheco, Thaynara L.
; Martins, Thiago F.
; Alvarenga, Thiago M.
; Carvalho, Thiago R. de
; Polizei, Thiago T.S.
; McElrath, Thomas C.
; Henry, Thomas
; Pikart, Tiago G.
; Porto, Tiago J.
; Krolow, Tiago K.
; Carvalho, Tiago P.
; Lotufo, Tito M. da C.
; Caramaschi, Ulisses
; Pinheiro, Ulisses dos S.
; Pardiñas, Ulyses F.J.
; Maia, Valéria C.
; Tavares, Valeria
; Costa, Valmir A.
; Amaral, Vanessa S. do
; Silva, Vera C.
; Wolff, Vera R. dos S.
; Slobodian, Verônica
; Silva, Vinícius B. da
; Espíndola, Vinicius C.
; Costa-Silva, Vinicius da
; Bertaco, Vinicius de A.
; Padula, Vinícius
; Ferreira, Vinicius S.
; Silva, Vitor C.P. da
; Piacentini, Vítor de Q.
; Sandoval-Gómez, Vivian E.
; Trevine, Vivian
; Sousa, Viviane R.
; Sant’Anna, Vivianne B. de
; Mathis, Wayne N.
; Souza, Wesley de O.
; Colombo, Wesley D.
; Tomaszewska, Wioletta
; Wosiacki, Wolmar B.
; Ovando, Ximena M.C.
; Leite, Yuri L.R.
.
ABSTRACT The limited temporal completeness and taxonomic accuracy of species lists, made available in a traditional manner in scientific publications, has always represented a problem. These lists are invariably limited to a few taxonomic groups and do not represent up-to-date knowledge of all species and classifications. In this context, the Brazilian megadiverse fauna is no exception, and the Catálogo Taxonômico da Fauna do Brasil (CTFB) (http://fauna.jbrj.gov.br/), made public in 2015, represents a database on biodiversity anchored on a list of valid and expertly recognized scientific names of animals in Brazil. The CTFB is updated in near real time by a team of more than 800 specialists. By January 1, 2024, the CTFB compiled 133,691 nominal species, with 125,138 that were considered valid. Most of the valid species were arthropods (82.3%, with more than 102,000 species) and chordates (7.69%, with over 11,000 species). These taxa were followed by a cluster composed of Mollusca (3,567 species), Platyhelminthes (2,292 species), Annelida (1,833 species), and Nematoda (1,447 species). All remaining groups had less than 1,000 species reported in Brazil, with Cnidaria (831 species), Porifera (628 species), Rotifera (606 species), and Bryozoa (520 species) representing those with more than 500 species. Analysis of the CTFB database can facilitate and direct efforts towards the discovery of new species in Brazil, but it is also fundamental in providing the best available list of valid nominal species to users, including those in science, health, conservation efforts, and any initiative involving animals. The importance of the CTFB is evidenced by the elevated number of citations in the scientific literature in diverse areas of biology, law, anthropology, education, forensic science, and veterinary science, among others. publications problem uptodate up date classifications context exception (CTFB http//fauna.jbrj.gov.br/, httpfaunajbrjgovbr http //fauna.jbrj.gov.br/ , jbrj gov br (http://fauna.jbrj.gov.br/) 2015 Brazil 80 specialists 1 2024 133691 133 691 133,69 125138 125 138 125,13 82.3%, 823 82 3 (82.3% 102000 102 000 102,00 7.69%, 769 7 69 (7.69% 11000 11 11,00 . 3,567 3567 567 (3,56 2,292 2292 2 292 (2,29 1,833 1833 833 (1,83 1,447 1447 447 (1,44 1000 1,00 831 (83 628 (62 606 (60 520 (52 50 users science health biology law anthropology education others http//fauna.jbrj.gov.br/ faunajbrjgovbr //fauna.jbrj.gov.br (http://fauna.jbrj.gov.br/ 201 8 202 13369 13 133,6 12513 12 125,1 82.3% (82.3 10200 10 00 102,0 7.69% 76 6 (7.69 1100 11,0 3,56 356 56 (3,5 2,29 229 29 (2,2 1,83 183 83 (1,8 1,44 144 44 (1,4 100 1,0 (8 62 (6 60 52 (5 5 http//fauna.jbrj.gov.br (http://fauna.jbrj.gov.br 20 1336 133, 1251 125, 82.3 (82. 1020 0 102, 7.69 (7.6 110 11, 3,5 35 (3, 2,2 22 (2, 1,8 18 (1, 1,4 14 4 ( 82. (82 7.6 (7. 3, (3 2, (2 (1 7. (7
8.
Antileishmanial activity of a dillapiole derivative obtained from Piper aduncum L. (Piperaceae) L Piperaceae (Piperaceae
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Barros, A. M. C.
; Pinto, A. C. S.
; Simplicio, F. G.
; Chaves, F. C. M.
; Franco, A. M. R.
; Lima, E. S.
.
Abstract Cutaneous leishmaniasis (CL) is considered a public health problem. Current treatments have disadvantages because they are invasive and have serious side effects, and thus there is a need for research into new, more effective pharmacological alternatives. Plants are promising sources of bioactive substances, and new analogues can be obtained through chemical reactions. The present study aimed to evaluate the antileishmanial effects of the analog dillapiole n-butyl ether (DBE) extracted from Piper aduncum leaves. The cytotoxic potential of DBE was evaluated at concentrations of 15.62 to 500 µM in peritoneal macrophages for 48 h, and in RAW 264.7 macrophages for 72 h using a dose-response method. The antileishmanial activity in L. amazonensis promastigotes used concentrations of 0.2 to 4.5 µM for 24, 48 and 72 h and the quantification of the cellular infection rate used a concentration of 4.5 µM of DBE against the amastigote forms internalized in macrophages for 24 h and 48 h. Nitric oxide was quantified from macrophages previously treated with DBE for 24 h and 48 h. The dosage of reactive oxygen species used a concentration of 4.5 µM of DBE incubated together with dichlorofluorescein acetate for 1, 3, 6, and 24 h. For the molecular modeling of DBE, the Leishmania protein, available in the “Protein Data Bank” database, was used. The studied molecule was not toxic to cells and presented a CC50 of 413 µM in peritoneal macrophages and 373.5 µM in RAW 264.7. The analogue inhibited promastigote forms of L. amazonensis with an IC50 of 1.6 µM for 72 h. DBE presented an infection rate of 17% and 12%, dillapiole of 24% and 14% and Pentacarinat® of 10% and 9% over 48 h. DBE demonstrated a binding energy of -7.8 for the U53 enzyme. It is concluded that the analogue showed promising antileishmanial activity for future in vivo tests. CL (CL problem alternatives substances reactions nbutyl n butyl (DBE leaves 1562 15 62 15.6 50 4 2647 264 7 264. doseresponse dose response method L 02 0 2 0. 45 5 4. 1 3 6 protein Protein Bank database CC CC5 41 3735 373 373. IC IC5 16 1. 17 12 12% 14 Pentacarinat 10 9 7.8 78 8 -7. U U5 enzyme tests 156 15. 26 37 7. -7 -
Resumo A leishmaniose cutânea (LC) é considerada um problema de saúde pública. Os tratamentos atuais apresentam desvantagens por serem invasivos e possuem efeitos colaterais graves, levando a pesquisa de novas alternativas farmacológicas mais eficazes. As plantas são fontes promissoras de bioativos, e por meio de reações químicas pode-se obter novos análogos. O presente estudo objetivou avaliar os efeitos antileishmania do análogo éter n-butil do dilapiol (EBD) extraído das folhas de Piper aduncum. Foi avaliado o potencial citotóxico do EBD nas concentrações de 15,62 a 500 µM em macrófagos peritoneais por 48 h, e em macrófagos RAW 264.7 por 72 h utilizando o método dose-resposta. A atividade antileishmania em promastigotas de L. amazonensis usou-se concentrações de 0,2 a 4,5 µM durante 24, 48 e 72 h e a quantificação da taxa de infecção celular usou-se uma concentração de 4,5 µM do EBD contra as formas amastigotas interiorizado em macrófagos por 24 h e 48 h. O óxido nítrico foi quantificado a partir de macrófagos tratados previamente com o EBD durante 24 h e 48 h. A dosagem das espécies reativas de oxigênio utilizou-se a concentração de 4,5 µM do EBD incubado junto ao acetato de diclorofluoresceína por 1, 3, 6, e 24 h. Para a modelagem molecular do EBD, usou-se a proteína de origem de Leishmania, disponível no banco de dados “Protein Data Bank”. A molécula do estudo não foi tóxica para as células, apresentou uma CC50 de 413 µM em macrófagos peritoneais e de 373,5 µM em RAW 264.7. O análogo inibiu as formas promastigotas de L. amazonensis com uma CI50 de 1,6 µM por 72 horas. O EBD apresentou uma taxa de infecção de 17% e 12%, dilapiol de 24% e 14% e Pentacarinat® de 10% e 9% durante 48 h. O EBD demonstrou uma ligação de energia de -7,8 pelo sítio de ação da enzima U53. Conclui-se que o análogo mostrou atividade antileishmania promissora para futuros testes in vivo. LC (LC pública graves eficazes bioativos podese pode se análogos nbutil n butil (EBD aduncum 1562 15 62 15,6 50 4 2647 264 7 264. doseresposta. doseresposta dose resposta. resposta dose-resposta L usouse usou 02 0 2 0, 45 5 4, utilizouse utilizou 1 3 6 Leishmania Protein Bank. Bank . Bank” células CC CC5 41 3735 373 373, CI CI5 16 horas 17 12 12% 14 Pentacarinat 10 9 7,8 78 8 -7, U53 U Concluise Conclui vivo 156 15, 26 37 7, -7 U5 -
9.
Third National Registry of Cardiac Rehabilitation Programs in Mexico (RENAPREC III-2022)
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Lara-Vargas, Jorge A.
; Ilarraza-Lomelí, Hermes
; García-Saldivia, Marianna
; Pineda-García, Alfredo D.
; Leyva-Valadez, Eduardo A.
; Justiniano-Cordero, Samuel
; Sahagún-Olmos, Roberto
; Zavala-Ramírez, Juana
; Cassaigne-Guasco, María E.
; Sánchez-Limón, Edgar-F
; Castañeda-López, Javier
; Cerón-Enríquez, Norma
; Ku-González, Andrés
; Arteaga-Martínez, Rodolfo
; Hinojosa-López, Tania
; Vergara-Guzmán, Jéssica
; Pérez-Vázquez, Daniel I.
; Gasca-Zamudio, Pedro D.
; Aranda-Ayala, Zulema L.
; Vacío-Reyes, Martha E.
; Reza-Orozco, Marco
; Alcocer-Gamboa, Miguel A.
; Hernández-González, Pedro A.
; Pérez-Reyes, Angélica A.
; Núñez-Urquiza, Juan P.
; Alonso-Sánchez, Jesús
; Franco-Valles, Sarahí
; Romo-Escamilla, Ricardo E.
; Nuriulú-Escobar, Patricia
; Serna-Santamaría, Iván
; Avilés-González, Jorge
; Salgado-Solorio, María C.
; Muñoz-Gutiérrez, Luz M.
; Mendoza-Díaz, Pedro M.
; Ávila-Estrada, Ángel
; Morales-Medina, Carlos
; Lara-Vázquez, Eduardo
; Rodríguez-Herrera, Paulina
; Galván-López, María
; Segoviano-Mendoza, Georgina
; De-la-Torre-Cruz, Fabiola
; Jiménez-Campos, Cecilia
; Ramírez-Meléndez, Alejandra
; Almaraz-Ríos, Alejandro
; González-Bonilla, Mezthly
; Rojano-Castillo, Jessica
; Rius-Suarez, María D.
.
resumen está disponible en el texto completo
Abstract Introduction: In Mexico, cardiac rehabilitation (CR) as an interdisciplinary intervention with therapeutic impact in patients with heart disease is growing. There is the need to know actual conditions of CR in our country. Objectives: The objective of this National Registry is to follow-up those existing and new CR units in Mexico through the comparison between the two previous registries, RENAPREC-2009 and RENAPREC II-2015 studies. This is a descriptive study focused on diverse CR activities such as assistance training, and certification of health professionals, barriers, reference, population attended, interdisciplinarity, permanence over time, growth prospects, regulations, post-pandemic condition, integrative characteristics, and scientific research. Results: Data were collected from 45 CR centers in the 32 states, 75.5% are private practice units, 67% are new, 33% were part of RENAPREC II-2015, and 17 have continued since 2009. With a better distribution of CR units along the territory, the median reference of candidates for CR programs is 9% with a significant reduction into tiempo of enrollment to Phase II admission (19 ± 11 days). Regarding to previous registries, the coverance of Phases I, II, and III is 71%, 100%, and 93%, respectively; and a coverance increases in evaluation, risk stratification, and prescription, more comprehensive attendance and prevention strategies. Conclusions: CR in Mexico has grown in the past 7 years. Even there is still low reference and heterogeneity in specific processes, there are strengths such as interdisciplinarity, scientific professionalization of specialists, national diversification, and an official society that are consolidated over time.
10.
Carbon Paste Electrodes Obtained from Organic Waste After a Biodrying Process and Validation in an Electro-Fenton System Towards Alternative Valorization
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Vela-Carrillo, A. Z.
; Godínez, Luis A.
; García-Espinoza, J. D.
; Martínez, R. J.
; Franco-Hernández, M. O.
; Piña-Guzman, A. B.
; Santos, M. C.
; Robles-Martínez, F.
; Robles, I.
.
Journal of the Mexican Chemical Society
- Métricas do periódico
Abstract. The transformation of agricultural waste into activated carbon represents an attractive approach as new and alternative source, but also as a reduction of pollution associated to the degradation of precursors. The organic residues sugarcane (Saccharum officinarum) bagasse-shell, orange (Citrus sinensis) peel-bagasse, and eucalyptus (Eucalyptus globulus) leaves, obtained from a biodrying process were transformed into activated carbons using phosphoric acid as activating agent. The resulting materials were physicochemically characterized and after that, carbonaceous electrodes were prepared to test the feasibility of using them in a discoloration electro-Fenton wastewater treatment process. Orange peel-bagasse biodried precursor transformed into activated carbon showed the highest efficiency when used as the modifier in a carbon paste electrode due to its highest porosity, electroactive area (24.9x10-2 cm2), and roughness (1.21 a.u.), also to its chemical affinity for anionic molecules. These properties, in addition to the capability of electro-sorb iron ions on the surface during the Fenton reaction, allowed a 44 % methyl orange discoloration efficiency. Sugarcane bagasse-peel and eucalyptus leaves biodried residues were also evaluated with efficiencies under 30 %, mainly attributed to intrinsic composition of the precursor materials.
Resumen. La transformación de los residuos agrícolas en carbón activado representa un enfoque atractivo y novedoso, además de que representa una alternativa a la reducción de la contaminación asociada a la degradación de residuos orgánicos. Los residuos orgánicos de bagazo de caña de azúcar (Saccharum officinarum), bagazo y cáscara de naranja (Citrus sinensis), y hojas de eucalipto (Eucalyptus globulus), que fueron obtenidos de un proceso de biosecado, se transformaron en carbón activado utilizando ácido fosfórico como agente activante. Los materiales resultantes se caracterizaron fisicoquímicamente y después de eso, se prepararon electrodos de pasta de carbón modificados con estos materiales, para estudiar la viabilidad de utilizarlos en un proceso de tratamiento de aguas residualesmediante electro-Fenton. El precursor biosecado de bagazo y cáscara de naranja transformado en carbón activado mostró la mayor eficiencia cuando se usó como modificador en un electrodo de pasta de carbón, debido a su mayor porosidad, área electroactiva (24.9x10-2 cm2) y rugosidad (1.21), también debido a su mayor afinidad química por moléculas aniónicas. Estas propiedades, aunadas a la capacidad de electro-sorber iones de hierro en la superficie durante la reacción de Fenton, permitieron una eficiencia de decoloración del naranja de metilo del 44 %. También se evaluaron residuos biosecados de bagazo de caña de azúcar y hojas de eucalipto, con eficiencias inferiores al 30 %, atribuidas principalmente a la composición intrínseca de los materiales precursores.
11.
Proximate composition, minerals, tannins, phytates and cooking quality of commercial cowpea cultivars composition minerals tannins
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Oliveira, Adolfo M. C. de
; Jean, Abdias
; Damasceno-Silva, Kaesel J.
; Moreira-Araújo, Regilda S. dos R.
; Franco, Luis J. D.
; Rocha, Maurisrael de M.
.
RESUMO O feijão-caupi é uma leguminosa de grande importância socioeconômica na região Nordeste do Brasil, sendo o tipo de feijão mais cultivado e consumido, representando a principal fonte de proteína vegetal de baixo custo das populações rural e urbana dessa região. O objetivo deste trabalho foi caracterizar a composição centesimal, minerais, taninos, ácido fítico e a qualidade de cozimento dos grãos integrais das cultivares de feijão-caupi BRS Aracê, BRS Inhuma e BRS Xiquexique. A composição centesimal foi determinada de acordo com a metodologia AOAC. Os minerais foram determinados por digestão nitro-perclórica e leitura em espectrofotômetro de absorção atômica de chama. Os fatores antinutricionais taninos e ácido fítico foram determinados por extração e leitura em espectrofotômetro. A qualidade do cozimento foi avaliada usando uma panela de pressão elétrica e, em seguida, o cozedor de Matsson. Foi utilizado o delineamento inteiramente casualizado (DIC), com três tratamentos (cultivares) e três repetições. Os dados foram submetidos à análise de variância e as médias comparadas pelo teste de Tukey (p<0,05). As cultivares apresentaram diferenças significativas (p<0,05) para a maioria das características avaliadas e similares para os teores de cinzas, lipídeos, fibra alimentar total e a maioria dos macrominerais. As cultivares BRS Aracê e BRS Xiquexique representam excelentes fontes de fibras dietéticas, proteínas e minerais, além de alta qualidade de cozimento, enquanto a cultivar BRS Inhuma destacou-se em carboidratos, fibras alimentares solúveis, valor energético total e baixos teores dos fatores antinutricionais analisados. feijãocaupi caupi Brasil consumido AOAC nitroperclórica nitro perclórica chama seguida Matsson DIC, DIC , (DIC) (cultivares repetições p<0,05. p005 p p<0,05 . 0 05 (p<0,05 cinzas lipídeos macrominerais dietéticas destacouse destacou se carboidratos solúveis analisados (DIC p00 p<0,0 (p<0,0 p0 p<0, (p<0, p<0 (p<0 p< (p< (p
ABSTRACT Cowpea is a socioeconomically important legume in the Northeast region of Brazil, and the most grown and consumed type of bean, representing the main source of low-cost vegetable protein for rural and urban populations in this region. The objective of this work was to characterize the proximate composition, minerals, tannins, phytic acid, and cooking quality of whole grains of cowpea from the commercial cultivars BRS Aracê, BRS Inhuma, and BRS Xiquexique. Grain samples of the cultivars were ground in a zirconium ball mill and the flour was used for analysis. The proximate composition was carried out according to the AOAC methodology. The minerals were determined by nitro-perchloric digestion and reading in a flame atomic absorption spectrophotometer. The anti-nutritional factors tannins and phytic acid were determined by extraction and reading in a spectrophotometer. Cooking quality was assessed using an electric pressure cooker and then a Mattson cooker. A completely randomized experimental design was used, with three treatments (cultivars) and three replications. The data were subjected to analysis of variance and the means were compared by the Tukey's test (p<0.05). The cowpea cultivars showed significant differences (p<0.05) for most characteristics evaluated and were similar in terms of ash, lipids, total dietary fiber, and most macrominerals. The results showed that grains of the cultivars BRS Aracê and BRS Xiquexique are excellent sources of dietary fiber, proteins, and minerals and present high cooking quality, while grains of the cultivar BRS Inhuma stood out regarding carbohydrates, soluble dietary fibers, total energetic value, and low levels of factors, anti-nutritional tannins and phytic acid. Brazil bean lowcost cost methodology nitroperchloric nitro perchloric spectrophotometer antinutritional anti nutritional (cultivars replications Tukeys Tukey s p<0.05. p005 p p<0.05 . 0 05 (p<0.05 ash lipids fiber macrominerals proteins carbohydrates fibers value p00 p<0.0 (p<0.0 p0 p<0. (p<0. p<0 (p<0 p< (p< (p
12.
A Seismological Study of the Michoacán-Colima, Mexico, Earthquake of 19 September 2022 (Mw7.6)
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Singh, S. K.
; Iglesias, A.
; Arroyo, D.
; Pérez-Campos, X.
; Ordaz, M.
; Mendoza, C.
; Corona-Fernández, R. D.
; Rivera, L.
; Espíndola, V. H.
; González-Ávila, D.
; Martínez-López, R.
; Castro-Artola, O.
; Santoyo, M. A.
; Franco, S. I.
.
Abstract Michoacán-Colima earthquake of 19 September 2022 (M s 7.6, M w7.6) ruptured the NW end of the Cocos-North American plate interface, causing severe damage to many towns and cities in the states of Michoacán and Colima. The damage was further exacerbated by a major aftershock (M w6.7) on 22 September. The mainshock initiated below the coast at a hypocentral distance of 22 km from the seismic station of Maruata (MMIG) where peak ground acceleration and velocity, PGA and PGV, of ~ 1 g and 28 cm/s were recorded. The epicenter of the major aftershock was located ~ 30 km SE of the mainshock. Finite fault modeling of the mainshock by the U.S. Geological Survey reveals a rupture propagation along the strike towards the NW and yields a static stress drop, Δσs, of 3.7 MPa. Our estimated radiated energy, E R, is 3.44×1015J, so that E R /M 0 is 1.27 × 10−5 similar to other large Mexican thrust earthquakes whose rupture areas do not extend to the trench. Aftershocks of the 2022 mainshock overlap that of the Colima earthquake of 30 January 1973 (M w7.6). Galitzin seismograms of the two earthquakes at DeBilt (DBN), The Netherlands, are reasonably similar so that they may be classified as quasi-repeated events. On the other hand, the DBN seismogram of the earthquake of 15 April 1941 (M S 7.7), whose location is poorly known but occurred in the same region, differs greatly from those of the 1973 and 2022 earthquakes, suggesting a different source area for the 1941 event. An analysis of the extensive regional recordings exhibits the effect of the directivity on the ground motion and on the ratio of ground motion during the mainshock to the major aftershock. The directivity explains the observed azimuthal dependence of PGA and PGV ratios, spectral ratios, and PGA and response spectra at 2s, Sa (T = 2 s). Because of the directivity, PGA, PGV, and Sa (T = 2 s) in the Valley of Mexico during the mainshock and the major aftershock were about the same in spite of the magnitude difference of 0.9. At CU (the reference, hard site in Mexico City), PGA and PGV during both events were ~ 6 cm/s2 and 2 cm/s, respectively, lower than expected for the mainshock and higher than expected for the aftershock.
Resumen El sismo de Michoacán-Colima el 19 de septiembre de 2022 (M s7.6, M w 7.6) rompió el límite NW de la interface entre las placas de Cocos y norteamericana, causando daño severo a muchas poblados y ciudades en los estados de Michoacán y Colima. El daño fue además agravado por una réplica de magnitud importante (M w6.7) el 22 de septiembre. El sismo principal inició debajo de la costa a una distancia hipocentral de 22 km de la estación sísmica de Maruata (MMIG) donde las aceleraciones y velocidades máximas registradas, PGA y PGV, fueron de 1g y 28 cm/s, respectivamente. El epicentro de la réplica más grande se localizó a ~30 km al SE del sismo principal. El modelado de falla finita del sismo principal presentado por el Servicio Geológico de los Estados Unidos (USGS), revela una propagación de la ruptura a lo largo del rumbo de la falla hacia la dirección NW con una caída de esfuerzos estáticos Δσs, of 3.7 MPa. Nuestra estimación de energía radiada, E R, es 3.44×1015J, de tal manera que E R /M 0 es de 1.27 × 10−5 valor similar al calculado para otros grandes sismos de subducción cuyas área de ruptura no se extienden hacia la trinchera. El área que contiene las réplicas del sismo principal de 2022 se traslapa con el área de réplicas del sismo del 30 de enero de 1973 (M w7.6). Los sismográmas Galitzin de los dos sismos registrados en la estación DeBilt (DBN) localizada en los Países Bajos son razonablemente similares de tal manera que pueden ser clasificados como eventos quasi-repetidos. Por otro lado, el sismograma DBN del sismo del 15 de abril de 1941 (M S 7.7), cuya localización no se conoce bien del todo, aunque se sabe que ocurre en la misma región, difiere sustancialmente de los sismogramas de 1972 y 2022, sugiriendo que el primero rompió un área diferente de la del sismo de 1941. Un análisis extensivo de registros regionales exhibe el efecto de directividad observada en los datos de movimientos fuertes y en los cocientes de aceleraciones del sismo principal y de las aceleraciones de la réplica mayor. La directividad explica la dependencia azimutal observada en los cocientes de PGA y PGV, los cocientes espectrales, la distribución de PGA y la respuesta espectral a 2s Sa (T = 2 s). Debido a la directividad, los valores de PGA, PGV y Sa (T = 2 s) en el Valle de México durante el sismo principal y la réplica mayor fueron muy similares a pesar de la diferencia en magnitud de 0.9. En CU (el sitio de roca firme de referencia en la Ciudad de México), PGA y PGV durante ambos eventos fueron de ~ 6 cm/s2 and 2 cm/s, respectivamente, valores más bajos que los esperados para el sismo principal y más altos que los esperados para la réplica mayor.
13.
ANÁLISIS MORFOLÓGICOS Y MOLECULARES RESPALDAN LA IDENTIDAD DE ARENARIA PYCNOPHYLLOIDES (CARYOPHYLLACEAE, ARENARIEAE) Y LA EXCLUSIÓN DEL GÉNERO SABULINA PARA LA FLORA ARGENTINA
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Resumen Zanotti, C. A.; F. E. Chiarini, S. von Mering & J. M. Acosta. 2022. Análisis morfológicos y moleculares respaldan la identidad de Arenaria pycnophylloides (Caryophyllaceae, Arenarieae) y la exclusión del género Sabulina para la Flora Argentina. Darwiniana, nueva serie 10(2): 435-450. Minuartia altoandina ha sido descrita como una especie endémica para el noroeste argentino, y posteriormente, transferida al género Sabulina. En la presente contribución, sobre la base de observaciones morfológicas y datos moleculares, se propone aquí a Sabulina altoandina como un sinónimo heterotípico de Arenaria pycnophylloides, especie nativa de las regiones altoandinas de Bolivia y del noroeste argentino; y como consecuencia, se excluye al género Sabulina de la Flora Argentina. Por otro lado, se sinonimiza a A. pycnophylloides var. compacta bajo A. pycnophylloides, y, además, el nombre de esta variedad se lectotipifica. Se brinda una descripción morfológica de A. pycnophylloides y se aporta una lámina fotográfica del taxón para facilitar la identificación de la especie. Adicionalmente, se presenta un mapa de distribución de la especie, y se excluye de la Flora de Perú.
Abstract Zanotti, C. A.; F. E. Chiarini, S. von Mering & J. M. Acosta. 2022. Morphological and molecular analysis support the identity of Arenaria pycnophylloides (Caryophyllaceae, Arenarieae), and the exclusion of the genera Sabulina from the Argentinian flora. Darwiniana, nueva serie 10(2): 435-450. Minuartia altoandina has been described as an endemic species for northwestern Argentina, and later transferred to the genus Sabulina. In this contribution and based on morphological observations and molecular data, Sabulina altoandina is proposed here as a heterotypic synonym of Arenaria pycnophylloides, a native species to the high Andean regions of Bolivia and northwestern Argentina; as a consequence, the genus Sabulina is excluded from the Argentinian Flora. On the other hand, A. pycnophylloides var. compacta is synonymized under A. pycnophylloides, and in addition, the name of this variety is lectotypified. A morphological description of A. pycnophylloides and a photographic plate of the taxon are provided to facilitate identification of the species. Additionally, a distribution map of the species is provided and is excluded from the Peruvian Flora.
14.
ENHANCED REMOVAL OF PERSISTENT CONTAMINANTS AND TOXICITY REDUCTION THROUGH THE APPLICATION OF A TRIPLE-STAGE FENTON PROCESS TO SANITARY LANDFILL LEACHATES FROM YUCATAN, MEXICO
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Escalante-Mañé, Ana M.
; Méndez-Novelo, Roger I.
; Giácoman-Vallejos, Germán
; González-Sánchez, Avel A.
; Romo-Alvarado, Jéssica
; Collí-Dulá, Reyna C.
; Quintal-Franco, Carlos A.
; Puch-Hau, Carlos
.
Sanitary landfill leachate (SLL) is a mixture of highly toxic and recalcitrant pollutants that threatens the water quality of the Yucatán Peninsula karst aquifer, one of the most extensive aquifers on the planet. To reduce the adverse environmental impacts of this wastewater, a triple-stage Fenton process (FP) was applied in an old SLL. Removal efficiencies were evaluated in terms of physicochemical variables, metal(oid)s concentrations, mass spectrometric identification of organic compounds and Daphnia magna acute toxicity test. The triple-stage FP achieved an 88% chemical oxygen demand (COD) removal, representing an improvement of 13% compared to FP performed in a single stage. Further, metal(oid)s such as aluminum, arsenic, chromium, nickel and zinc as well as organic compounds were substantially reduced. With respect to acute toxicity, the treatment produced a 64% reduction. Thus, this treatment system seems to be an effective option to reduce the dangerous level of SLL.
15.
Safety and efficacy of arteriovenous fistula angioplasties performed by nephrologists: report from a Brazilian interventional nephrology center
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Franco, Ricardo P.
; Riella, Miguel C.
; Chula, Domingos C.
; Alcântara, Marcia T. de
; Nascimento, Marcelo M. do
.
RESUMO Introdução: As fístulas arteriovenosas (FAV) são a primeira escolha de acesso vascular para hemodiálise. No entanto, elas apresentam uma alta incidência de estenoses venosas levando à trombose. Embora o treinamento em nefrologia intervencionista possa melhorar a acessibilidade para o tratamento das estenoses venosas, há dados limitados sobre a segurança e a eficácia desta abordagem realizada por nefrologistas treinados em países em desenvolvimento e de baixa renda. Métodos: Este estudo apresenta os resultados retrospectivos de angioplastias de FAV realizadas por nefrologistas treinados em um centro ambulatorial brasileiro de nefrologia intervencionista. O desfecho primário foi a taxa de sucesso técnico (conclusão do procedimento com angioplastia de todas as estenoses) e os desfechos secundários foram taxas de complicação e a patência geral das FAV. Achados: Duzentas e cinquenta e seis angioplastias foram realizadas em 160 FAV. A taxa de sucesso técnico foi de 88,77% e a principal causa de falha técnica foi a oclusão venosa (10%). A incidência de complicações foi de 13,67%, com apenas um paciente necessitando de internação e quatro acessos perdidos devido à presença de hematomas e/ou trombose. Hematomas de grau 1 foram a complicação mais frequente (8,2%). A patência geral encontrada foi de 88,2 e 80,9% a 180 e 360 dias após o procedimento, respectivamente. Conclusão: Nossos achados sugerem que a angioplastia de FAV realizada por nefrologistas treinados tem taxas de sucesso e patência aceitáveis, com uma baixa incidência de complicações maiores, bem como uma baixa necessidade de hospitalização.
ABSTRACT Introduction: Arteriovenous fistulas (AVF) are the first choice vascular access for hemodialysis. However, they present a high incidence of venous stenosis leading to thrombosis. Although training in interventional nephrology may improve accessibility for treatment of venous stenosis, there is limited data on the safety and efficacy of this approach performed by trained nephrologists in low-income and developing countries. Methods: This study presents the retrospective results of AVF angioplasties performed by trained nephrologists in a Brazilian outpatient interventional nephrology center. The primary outcome was technical success rate (completion of the procedure with angioplasty of all stenoses) and secondary outcomes were complication rates and overall AVF patency. Findings: Two hundred fifty-six angioplasties were performed in 160 AVF. The technical success rate was 88.77% and the main cause of technical failure was venous occlusion (10%). The incidence of complications was 13.67%, with only one patient needing hospitalization and four accesses lost due to the presence of hematomas and/or thrombosis. Grade 1 hematomas were the most frequent complication (8.2%). The overall patency found was 88.2 and 80.9% at 180 and 360 days after the procedure, respectively. Conclusion: Our findings suggest that AVF angioplasty performed by trained nephrologists has acceptable success rates and patency, with a low incidence of major complications as well as a low need for hospitalization.
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