Pesquisa | SciELO

RESUMEN La menta piperita es una planta medicinal, su cultivo es considerado un interesante rubro de renta, sin embargo, es susceptible al déficit hídrico, siendo ésta la causa principal de los bajos rendimientos de este cultivo en parcelas sin sistema de riego. Con el objetivo de evaluar parámetros productivos y económicos del cultivo de menta piperita con coberturas orgánicas e inorgánicas de suelo que ayuden reducir el déficit hídrico, se llevó a cabo esta investigación en un diseño completamente al azar, compuesto por cinco tratamientos (suelo sin cobertura, mulching negro, mulching blanco, cascarilla de arroz y pasto pacholí) y cuatro repeticiones, totalizando 20 unidades experimentales. Las variables evaluadas fueron: longitud de brotes basales, cantidad de brotes basales y brotes laterales, rendimiento de masa fresca y seca. Adicionalmente, se analizó la rentabilidad de cada tipo de cobertura. Todas las medias fueron sometidas al análisis de varianza (ANAVA) y comparadas por el Test de Tukey al 5%. En cuanto a la longitud de brotes basales, los mejores resultados fueron con la utilización de mulching negro, seguido por el mulching blanco y pasto pacholí; la mayor cantidad de brotes laterales con 16,45 con el mulching blanco, en cambio en la cantidad de brotes basales fue el testigo que presentó una mayor cantidad con 4,15. El mulching blanco presentó mayor rendimiento que el testigo para la masa fresca y masa seca con 1.544 kg ha-1 y 628 kg ha-1, respectivamente. Al analizar la rentabilidad en la masa fresca de la menta piperita, la utilización del mulching blanco fue más factible, mientras que en masa seca se observó una rentabilidad negativa para todos los tratamientos.

ABSTRACT Peppermint is a medicinal plant, being an interesting income item, however it is susceptible to water deficit, this being the main cause of the low yields of this item in plots without an irrigation system. With the objective of evaluating productive and economic parameters of peppermint with organic and inorganic soil covers, this research was carried out in a completely randomized design, composed of five treatments (soil without cover, black mulching, white mulching, rice husk and patcholí grass) and four repetitions, totaling 20 experimental units. The variables evaluated were: length of basal shoots, number of basal shoots and lateral shoots, yield of fresh and dry mass, cost/benefit profitability of each type of coverage. All means were subjected to the analysis of variance (ANAVA) and the means were compared by the Tukey Test at 5%. Regarding the length of basal shoots, the best results were with black mulching, followed by white mulching and patchouli grass; the greatest number of lateral shoots with 16.45 with the white mulching, on the other hand, in the number of basal shoots, the control had the highest number with 4.15. The white mulching presented a higher yield than the control for the fresh mass with 1,544 kg ha-1 and dry mass of 628 kg ha-1. When analyzing the profitability in the fresh mass of peppermint, the use of white mulching was more feasible and in dry mass they showed negative profitability for white mulching.

https://doi.org/10.18004/investig.agrar.2024.junio.2601791

Anticuerpos monoclonales para Virus Respiratorio Sincicial (VRS) en pacientes con Atrofia Muscular Espinal Tipo 1
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Valdebenito Parra, Carlos

; Prado Atlagic, Francisco

; Huerta Armijo, Antonio

Andes pediatrica

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

Jun 2024, Volume 95 Nº 3 Páginas 328 - 329

Resumo: Es | Texto: Es | PDF: Es

https://doi.org/10.32641/andespediatr.v95i3.5227

Os contributos da Enfermagem para a reforma da saúde mental em Portugal
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Narigão, Miguel

; Nabais, António Antunes

; Mendes, Artur

; Sampaio, Francisco

; Santos, José Carlos

; Fernandes, Manuela

Revista Portuguesa de Enfermagem de Saúde Mental

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

Jun 2024, Nº 31 Páginas 3 - 11

Resumo: Es En Pt | Texto: Es En Pt | PDF: Es | PDF: En | PDF: Pt

Resumen La transformación de la atención de salud mental en Portugal en los últimos años ha sido fundamental para una mayor humanización, una mejor organización y proximidad. Con un enfoque predominantemente comunitario, las enfermeras de salud mental desempeñan un papel importante en su implementación debido a sus conocimientos y prácticas dentro de equipos interdisciplinarios. Contribuyen a través de intervenciones conjuntas y autónomas a lo largo del ciclo vital, promoviendo la salud mental, interpretando el sufrimiento mental y brindando apoyo en enfermedades mentales, tanto en entornos comunitarios como hospitalarios.

Abstract The transformation of mental healthcare in Portugal in recent years has been instrumental in promoting greater humanisation, improved organisation, and proximity to patients. With a predominantly community-focused approach, mental health nurses play a crucial role in its implementation through their knowledge and practice within interdisciplinary teams. They contribute through joint and autonomous interventions across the lifespan, promoting mental health, interpreting mental distress, and providing support for mental illness in community and hospital settings.

Resumo A transformação dos cuidados de saúde mental em Portugal, nos anos recentes tem sido determinante para uma maior humanização, melhor organização e proximidade. Com um foco predominantemente comunitário, os enfermeiros especialistas em Enfermagem de Saúde Mental e Psiquiátrica têm um importante papel na sua implementação, pelo seu conhecimento e prática, incluídos em equipas interdisciplinares, dando contributos através de intervenções conjuntas e autónomas, ao longo do ciclo vital, através da promoção da saúde mental, interpretação do sofrimento mental e acompanhamento na doença mental, em contextos comunitários e hospitalares.

https://doi.org/10.19131/rpesm.376

Atrofia Muscular Espinal de presentación temprana, perspectivas de su tratamiento en Chile
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Valdebenito Parra, Carlos

; Prado Atlagic, Francisco

; Huerta Armijo, Antonio

; Aros Aránguiz, Sofía

Andes pediatrica

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

Fev 2024, Volume 95 Nº 1 Páginas 110 - 112

Resumo: Es | Texto: Es | PDF: Es

https://doi.org/10.32641/andespediatr.v95i1.5087

Atingimento das Metas de Colesterol LDL em Pacientes com Histórico de Infarto Agudo do Miocárdio: Estudo Transversal do Mundo Real Miocárdio
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Gomes, Daniel A.

; Paiva, Mariana Sousa

; Freitas, Pedro

; Albuquerque, Francisco

; Lima, Maria Rita

; Santos, Rita Reis

; Presume, João

; Trabulo, Marisa

; Aguiar, Carlos

; Ferreira, Jorge

; Ferreira, António M.

; Mendes, Miguel

Arquivos Brasileiros de Cardiologia

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

Jan 2024, Volume 121 Nº 1 elocation e20230242

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

Abstract Background: The European Society of Cardiology guidelines recommend an LDL-cholesterol (LDL-C) < 55 mg/dL for patients with established cardiovascular disease. While the Friedewald equation to estimate LDL-C is still widely used, the newer Martin-Hopkins equation has shown greater accuracy. Objectives: We aimed to assess: A) the proportion of patients reaching LDL-C goal and the therapies used in a tertiary center; B) the impact of using the Martin-Hopkins method instead of Friedewald’s on the proportion of controlled patients. Methods: A single-center cross-sectional study including consecutive post-myocardial infarction patients followed by 20 cardiologists in a tertiary hospital. Data was collected retrospectively from clinical appointments that took place after April 2022. For each patient, the LDL-C levels and attainment of goals were estimated from an ambulatory lipid profile using both Friedewald and Martin-Hopkins equations. A two-tailed p-value of < 0.05 was considered statistically significant for all tests. Results: Overall, 400 patients were included (aged 67 ± 13 years, 77% male). Using Friedewald’s equation, the median LDL-C under therapy was 64 (50-81) mg/dL, and 31% had LDL-C within goals. High-intensity statins were used in 64% of patients, 37% were on ezetimibe, and 0.5% were under PCSK9 inhibitors. Combination therapy of high-intensity statin + ezetimibe was used in 102 patients (26%). Applying the Martin-Hopkins method would reclassify a total of 31 patients (7.8%). Among those deemed controlled by Friedewald’s equation, 27 (21.6%) would have a Martin-Hopkins’ LDL-C above goals. Conclusions: Less than one-third of post-myocardial infarction patients had LDL-C within the goal. Applying the Martin-Hopkins equation would reclassify one-fifth of presumably controlled patients into the non-controlled group. Background LDLcholesterol LDL cholesterol LDLC C (LDL-C 5 mgdL mg dL disease MartinHopkins Martin Hopkins accuracy Objectives assess center B Friedewalds s Methods singlecenter single crosssectional cross sectional postmyocardial post myocardial 2 hospital 2022 patient equations twotailed two tailed pvalue p value 005 0 05 0.0 tests Results Overall 40 aged 6 1 years 77 male. male . male) 5081 50 81 (50-81 Highintensity High intensity 37 0.5 PCSK inhibitors highintensity high 10 26%. 26 26% (26%) 3 7.8%. 78 7.8% 7 8 (7.8%) 21.6% 216 21 (21.6% Conclusions onethird one third onefifth fifth noncontrolled non group 202 00 0. 4 508 (50-8 (26% 7.8 (7.8% 21.6 (21.6 (50- (26 7. (7.8 21. (21. (50 (2 (7. (21 (5 ( (7

Resumo Fundamento: As diretrizes da Sociedade Europeia de Cardiologia recomendam um nível de colesterol LDL (LDL-C) < 55 mg/dL para pacientes com doença cardiovascular estabelecida. Embora a fórmula de Friedewald ainda seja amplamente utilizada para estimar o LDL-C, a fórmula mais recente de Martin-Hopkins mostrou maior precisão. Objetivos: Nosso objetivo foi avaliar: A) a proporção de pacientes que atingiram a meta de LDL-C e as terapias utilizadas em um centro terciário; B) o impacto da utilização do método de Martin-Hopkins em vez do método de Friedewald na proporção de pacientes controlados. Métodos: Estudo transversal monocêntrico, incluindo pacientes consecutivos pós-infarto do miocárdio, acompanhados por 20 cardiologistas, em um hospital terciário. Os dados foram coletados retrospectivamente de consultas clínicas realizadas após abril de 2022. Para cada paciente, os níveis de LDL-C e o atingimento das metas foram estimados a partir de um perfil lipídico ambulatorial, utilizando as fórmulas de Friedewald e Martin-Hopkins. Um valor-p bicaudal < 0,05 foi considerado estatisticamente significativo para todos os testes. Resultados: Foram incluídos 400 pacientes (com 67 ± 13 anos, 77% do sexo masculino). Utilizando a fórmula de Friedewald, a mediana de LDL-C sob terapia foi de 64 (50-81) mg/dL, e 31% tinham LDL-C dentro da meta. Estatinas de alta intensidade foram usadas em 64% dos pacientes, 37% estavam em uso de ezetimiba e 0,5% estavam em uso de inibidores de PCSK9. A terapia combinada de estatina de alta intensidade + ezetimiba foi utilizada em 102 pacientes (26%). A aplicação do método de Martin-Hopkins reclassificaria um total de 31 pacientes (7,8%). Entre aqueles considerados controlados pela fórmula de Friedewald, 27 (21,6%) teriam LDL-C estimado por Martin-Hopkins acima da meta. Conclusões: Menos de um terço dos pacientes pós-infarto do miocárdio apresentaram LDL-C dentro da meta. A aplicação da fórmula de Martin-Hopkins reclassificaria um quinto dos pacientes presumivelmente controlados no grupo de pacientes não controlados. Fundamento LDLC C (LDL-C 5 mgdL mg dL estabelecida LDLC, C, MartinHopkins Martin Hopkins precisão Objetivos avaliar terciário B Métodos monocêntrico pósinfarto pós infarto 2 cardiologistas 2022 paciente ambulatorial MartinHopkins. Hopkins. valorp valor p 005 0 05 0,0 testes Resultados 40 6 1 anos 77 masculino. masculino . masculino) 5081 50 81 (50-81 37 0,5 PCSK9 PCSK 10 26%. 26 26% (26%) 3 7,8%. 78 7,8% 7 8 (7,8%) 21,6% 216 21 (21,6% Conclusões 202 00 0, 4 508 (50-8 (26% 7,8 (7,8% 21,6 (21,6 (50- (26 7, (7,8 21, (21, (50 (2 (7, (21 (5 ( (7

https://doi.org/10.36660/abc.20230242

Atrofia Muscular Espinal de presentación temprana, perspectivas de su tratamiento en Chile
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Valdebenito Parra, Carlos

; Prado Atlagic, Francisco

; Huerta Armijo, Antonio

; Aros Aránguiz, Sofía

Andes pediatrica

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

2024, Nº ahead

Resumo: Es | Texto: Es | PDF: Es

https://doi.org/10.32641/andespediatr.v95i1.5087

Impact of pre-operative weight loss on non-alcoholic fatty liver disease histopathology and insulin resistance in individuals undergoing bariatric surgery: a propensity matched cross-sectional comparison preoperative pre operative nonalcoholic non alcoholic surgery crosssectional cross sectional
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Maldonado, Fábio Henrique Ribeiro

; Mega, Paulo Ferreira

; Germano, Carlos Wustemberg

; Dias, Luana Leite Castilho

; Callejas, Guilherme Hoverter

; Gestic, Martinho Antonio

; Utrini, Murillo Pimentel

; Chaim, Felipe David Mendonça

; Callejas-Neto, Francisco

; Chaim, Elinton Adami

; Cazzo, Everton

Sao Paulo Medical Journal

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

2024, Volume 142 Nº 1 elocation e2022663

Resumo: En | Texto: En | PDF: En

ABSTRACT BACKGROUND: The effect of weight loss (WL) on histopathological aspects of non-alcoholic fatty liver disease (NAFLD) may provide further insights into the dynamics of hepatic recovery after WL. OBJECTIVE: To analyze the effects of pre-operative WL on insulin resistance- and NAFLD-related histology in individuals undergoing bariatric surgery (BS) with or without pre-operative WL. DESIGN AND SETTING: A matched cross-sectional study was conducted at a public university hospital and a private clinic in Campinas, Brazil. METHODS: An analytical, observational, cross-sectional study was conducted using prospectively collected databases of individuals who underwent BS and liver biopsy at either a public tertiary university hospital (with pre-operative WL) or a private clinic (without pre-operative WL). Random electronic matching by gender, age, and body mass index (BMI) was performed and two paired groups of 24 individuals each were selected. RESULTS: Of the 48 participants, 75% were female. The mean age was 37.4 ± 9.6. The mean BMI was 38.9 ± 2.6 kg/m2. Fibrosis was the most common histopathological abnormality (91.7%). Glucose was significantly lower in the WL group (92 ± 19.1 versus 111.8 ± 35.4 mg/dL; P = 0.02). Significantly lower frequencies of macrovesicular steatosis (58.3% versus 95.8%; P = 0.004), microvesicular steatosis (12.5% versus 87.5%; P < 0.001), and portal inflammation (50% versus 87.5%; P = 0.011) were observed in the WL group. CONCLUSION: Pre-operative WL was significantly associated with lower frequencies of macro- and mi- crovesicular steatosis, portal inflammation, and lower glycemia, indicating an association between the recent trajectory of body weight and histological aspects of NAFLD. BACKGROUND (WL nonalcoholic non alcoholic NAFLD (NAFLD OBJECTIVE preoperative pre operative resistance NAFLDrelated related (BS SETTING crosssectional cross sectional Campinas Brazil METHODS analytical observational . gender (BMI 2 selected RESULTS 4 participants 75 female 374 37 37. 96 9 6 9.6 389 38 38. 26 2. kgm2 kgm kg m2 m kg/m2 91.7%. 917 91.7% 91 7 (91.7%) 92 (9 191 19 1 19. 1118 111 8 111. 354 35 35. mg/dL mgdL mg dL 0.02. 002 0.02 0 02 0.02) 58.3% 583 58 3 (58.3 95.8% 958 95 0.004, 0004 0.004 , 004 0.004) 12.5% 125 12 5 (12.5 87.5% 875 87 0.001, 0001 0.001 001 0.001) 50% 50 (50 0.011 0011 011 CONCLUSION Preoperative Pre macro mi glycemia 9. kg/m 91.7 (91.7% ( 11 00 0.0 58.3 (58. 95.8 000 0.00 12.5 (12. 87.5 (5 0.01 01 91. (91.7 0. 58. (58 95. 12. (12 87. (91. (1 (91

https://doi.org/10.1590/1516-3180.2022.0663.r1.24042023

Agronomic performance of ‘BRS Melodia’ seedless table grape grafted onto different rootstocks BRS Melodia
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Oliveira, Carlos Roberto Silva de

; Silva, Francismary Barros da

; Pontes, Glácia Maria de Alencar

; Mendonça Júnior, Antonio Francisco

; Leão, Patrícia Coelho de Souza

Bragantia

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

2024, Volume 83 elocation e20230245

Resumo: En | Texto: En | PDF: En

ABSTRACT The seedless table grape ‘BRS Melodia’ stands out for its pink color and the special flavor of red berries, which make for commercial classification as gourmet type grapes. Cultivation of this new table grape cultivar is expanding in the São Francisco Valley, in the Brazilian Northeast region. The aim of this study was to determine the effect of the rootstock on vigor, on yield components, and on physicochemical characteristics of ‘BRS Melodia’ grapes grown under the semi-arid tropical conditions of the São Francisco Valley. The experiment was carried out under irrigated cultivation in a commercial area in the municipality of Casa Nova, Bahia, Brazil, from 2021 to 2023. Treatments consisted of the rootstocks 101-14 MgT, IAC 313, IAC 572, IAC 766, Paulsen 1103, Ramsey, SO4, and Teleki 5C in a randomized block experimental design with four replications. There was no effect of the rootstock on the following variables: branch and leaf fresh matter, sprouting percentage, total soluble solids content (SS), titratable acidity (TA), and SS/TA ratio. ‘BRS Melodia’ grapevines had high vigor regardless of the rootstock used. The Ramsey rootstock led to reduced bud fertility compared to IAC 572 and IAC 766. As the vines advanced in age, the rootstocks IAC 572 and IAC 766 provided the highest yields and number of clusters per vine. The physicochemical characteristics of the ‘BRS Melodia’ grapes meet the standards required for commercialization on all the rootstocks used. BRS Melodia berries Valley region components semiarid semi arid Nova Bahia Brazil 202 2023 10114 101 14 101-1 MgT 313 1103 SO4 SO C replications variables matter percentage SS, SS , (SS) TA, TA (TA) SSTA ratio used 57 age 76 vine 20 1011 10 1 101- 31 110 (SS (TA 5 7 2 3 11

https://doi.org/10.1590/1678-4499.20230245

Forty years of a Postgraduate Program in Cardiology at a Brazilian public university: indicators of its graduates university
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Braga Filho, Carlos Eduardo

; Silva, Talita Dias da

; Silva, Claudia Joanete da

; Santos, Cleidivan Alves dos

; Rodrigues, Frank Menezes

; Barbosa, Adriano Henrique Pereira

; Caixeta, Adriano

; Izar, Maria Cristina de Oliveira

; Luna-Filho, Bráulio

; Fonseca, Francisco Antonio Helfenstein

; Tallo, Fernando Sabia

; Roever, Leonardo

; Caricati-Neto, Afonso

; Menezes-Rodrigues, Francisco Sandro

Acta Cirúrgica Brasileira

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

2024, Volume 39 elocation e394824

Resumo: En | Texto: En | PDF: En

ABSTRACT Purpose: To evaluate the profile of graduates of the Postgraduate Program (PGP) in Cardiology of a public federal university, according to sociodemographic factors and professional trajectory. Methods: The variables were collected from databases from the observed institution and digital platforms. The analysis of differences between the various levels of degrees was carried out in three cohorts: the entire historical series (graduates from 1978–2021), the first 20 years (1978–1997) and the second 20 years (1998–2018). Results: The results demonstrated that most students from the PGP completed a PhD and are men over 30 years old, they came from public universities and the Southeast region. In the first 20 years, significant differences were observed in the distribution of masters and doctors working professionally at the institution analyzed, as well as in the age of the students. In the 20 years of the second half, there were differences between masters and PhD working professionally in the institution itself, as they came from private universities, they are women and PhD. Conclusions: The changes in the profile of masters and PhD that graduated from this PGP in cardiology reflect transformations that occurred in the job market and academy over the decades. Purpose (PGP university trajectory Methods platforms cohorts 1978–2021, 19782021 1978–2021 , 1978 2021 1978–2021) 2 1978–1997 19781997 1997 (1978–1997 1998–2018. 19982018 1998–2018 . 1998 2018 (1998–2018) Results 3 old region analyzed half itself Conclusions decades 1978202 1978–202 197 202 1978–199 1978199 199 (1978–199 1998201 1998–201 201 (1998–2018 197820 1978–20 19 1978–19 197819 (1978–19 199820 1998–20 (1998–201 19782 1978–2 1 1978–1 19781 (1978–1 19982 1998–2 (1998–20 1978– (1978– 1998– (1998–2 (1978 (1998– (197 (1998 (19 (199 (1 (

https://doi.org/10.1590/acb394824

10.

Semisynthesis and Cytotoxic Activities of Novel Oxime Ester Derivatives of the Diterpene Stemodin
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Oliveira, José Augusto C. de

; Alves Filho, Carlos José

; Lima, Antônio Marcelo A.

; Pessoa, Cláudia do Ó

; Oliveira, Fátima de Cássia E. de

; Miranda, Fátima N.

; Mattos, Marcos Carlos de

; Oliveira, Maria Conceição F.

; Mafezoli, Jair

; Barbosa, Francisco Geraldo

Journal of the Brazilian Chemical Society

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

2024, Volume 35 Nº 6 elocation e-20230193

Resumo: En | Texto: En | PDF: En

Stemodin (1) is a diterpene produced by Stemodia maritima L. (Scrophulariaceae) and shows antiviral and tumor cell proliferation inhibitory activities. Chemical modifications of 1 were performed to produce the known stemodinone (2), two new stemodinone oximes, Z (3) and E (4), and seven new oxime esters derivatives (5, 6, 7, 8, 9, 10, and 11). All derivatives were evaluated for their cytotoxic activity in HL60 (promyelocytic leukemia), SNB-19 (astrocytoma), HCT-116 (colon carcinoma), and PC3 (prostate) human cancer cell lines, and L929 (healthy murine cells). Oximes 3 and 4 showed lower cytotoxic values than 1 against all cancer cell lines tested. However, esters 9 and 10 exhibited cell growth inhibition percentages higher than 1 against PC3, SNB-19, and HCT-116 cancer cell lines, ranging from 62.96 to 94.27%. Many of these values exceed that presented by doxorubicin (66.05-86.87%). All compounds showed no cytotoxic effect on healthy cells at the tested concentration of 25 µg mL-1. (1 L Scrophulariaceae (Scrophulariaceae activities 2, 2 , (2) oximes (3 4, (4) 5, 5 (5 6 7 8 11. 11 . 11) HL HL6 promyelocytic leukemia, leukemia leukemia) SNB19 SNB 19 SNB-1 astrocytoma, astrocytoma (astrocytoma) HCT116 HCT 116 HCT-11 colon carcinoma, carcinoma carcinoma) PC prostate (prostate L92 cells. cells) However SNB19, 19, 6296 62 96 62.9 9427 94 27 94.27% 66.0586.87%. 66058687 66.05 86.87% 66 05 86 87 (66.05-86.87%) mL1. mL1 mL 1. mL-1 ( (2 (4 SNB1 SNB- (astrocytoma HCT11 HCT-1 L9 629 62. 942 94.27 0586 66.0586.87% 6605868 6605 66.0 8687 86.87 0 (66.05-86.87% mL- HCT1 HCT- 94.2 058 66.0586.87 660586 660 66. 868 86.8 (66.05-86.87 94. 66.0586.8 66058 86. (66.05-86.8 66.0586. (66.05-86. 66.0586 (66.05-86 66.058 (66.05-8 (66.05- (66.05 (66.0 (66. (66 (6

https://doi.org/10.21577/0103-5053.20230193

11.

Mechanical characterization of an alternative laterite gravel used as pavement material
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Guimarães, Antonio Carlos Rodrigues

; Lima, Caroline Dias Amancio de

; Aragão, Francisco Thiago Sacramento

; Motta, Laura Maria Goretti da

; Santos, Juliana Tanabe Assad dos

Soils and Rocks

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

2024, Volume 47 Nº 1 elocation e2024010622

Resumo: En | Texto: En | PDF: En

Abstract Laterite gravels have been successfully adopted as pavement materials in the field. Despite that, they are often rejected in material selection processes because of its base on traditional gradation and consistency limits requirements. To allow a deeper evaluation of such material found abundantly in tropical countries, along to characterizing traditional parameters, repeated load triaxial tests were performed in a Laterite Gravel from Acre/Brazil to evaluate its elastic and plastic behavior through Resilient Modulus (RM) and Permanent Deformation (PD), respectively. In addition, a simulation was conducted in the MeDiNa software, based on the test results considering stress states that are usually applied in pavement layers. The material showed RM values higher than 500 MPa, which was considered high compared to materials such as Quartz and Granite. It was also observed low permanent deformation (below 1 mm for higher tensions applied) and accommodation of displacement (shakedown) for most specimens. The simulation results showed low rutting prediction for the Laterite Gravel applied in highway pavement layers. Thus, the results indicated that the lateritic gravel can be adopted in the composition of base or subbase layers of flexible pavements, even though some limits of the parameters specified by traditional specifications were violated, as expected. In addition, we also highlight the need for adoption of new material selection strategies that are based on key mechanical characteristics to avoid discarding potentially well performing materials. field requirements countries AcreBrazil Acre Brazil (RM PD, PD , (PD) respectively addition software 50 MPa Granite below shakedown (shakedown specimens Thus pavements violated expected (PD 5

https://doi.org/10.28927/sr.2024.010622

12.

Role of Computed Tomography Angiography in the Short-Term Follow-up of Aortic Coarctation Repair ShortTerm Short Term Followup Follow up
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Cardoso, Mariana Ribeiro Rodero

; Crestani, Ariela Maltarolo

; Souza, Antônio Soares

; Braga, Fernanda Del Campo Braojos

; Brun, Marília Maroneze

; Murakami, Alexandre Noboru

; Cajueiro, Francisco Candido Monteiro

; Marchi, Carlos Henrique De

; Croti, Ulisses Alexandre

Brazilian Journal of Cardiovascular Surgery

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

2024, Volume 39 Nº 1 elocation e20230220

Resumo: En | Texto: En | PDF: En

ABSTRACT Introduction: Coarctation of the aorta (CoA) is a narrowing of the thoracic aorta that often manifests as discrete stenosis but may be tortuous or in long segment. The study aimed to evaluate pre and post-surgical aspects of pediatric patients submitted to CoA surgical correction and to identify possible predisposing factors for aortic recoarctation. Methods: Twenty-five patients were divided into groups according to presence (N=8) or absence (N=17) of recoarctation after surgical correction of CoA and evaluated according to clinical-demographic profile, vascular characteristics via computed angiotomography (CAT), and other pathological conditions. Results: Majority of males (64%), ≥ 15 days old (76%), ≥ 2.5 kg (80%). There was similarity between groups with and without recoarctation regarding sex (male: 87% vs. 53%; P=0.277), age (≥ 15 days: 62.5 vs. 82%; P=0.505), and weight (≥ 2.5 kg: 87.5 vs. 76.5; P=0,492). Altered values of aortic root/Valsalva diameter, proximal transverse arch, and distal isthmus, and normal values for aorta prevailed in preoperative CAT. Normal values for the aortic root/Valsalva sinus diameter were observed with and without recoarctation, the same for both groups regarding ascending and descending aorta in postoperative CAT. No significant difference for altered values of proximal transverse arch and alteration in distal isthmus was observed. Conclusion: No predictive risk for recoarctation was observed. CTA proved to be important in CoA diagnosis and management, since CoA is mainly related with altered diameter of aortic root/sinus of Valsalva and proximal and distal aortic arch/isthmus, however, it failed to show predictive risk for recoarctation. Introduction (CoA segment postsurgical post Methods Twentyfive Twenty five N=8 N8 N 8 (N=8 N=17 N17 17 (N=17 clinicaldemographic clinical demographic profile CAT, CAT , (CAT) conditions Results 64%, 64 64% (64%) 1 76%, 76 76% (76%) 25 2 5 2. 80%. 80 80% . (80%) male (male 87 vs 53% 53 P=0.277, P0277 P P=0.277 0 277 P=0.277) ( 625 62 62. 82% 82 P=0.505, P0505 P=0.505 505 P=0.505) 875 87. 76.5 765 P=0,492. P0492 P=0,492 492 P=0,492) rootValsalva root Conclusion management rootsinus archisthmus arch/isthmus however N= (N= N=1 N1 (N=1 (CAT 6 (64% 7 (76% (80% P027 P=0.27 27 P050 P=0.50 50 76. P049 P=0,49 49 (N (64 (76 (80 P02 P=0.2 P05 P=0.5 P04 P=0,4 4 (6 (7 (8 P0 P=0. P=0, P=0 P=

https://doi.org/10.21470/1678-9741-2023-0220

13.

SPECIAL ISSUE ON APPLICATIONS OF OPERATIONS RESEARCH IN THE PUBLIC SECTOR: FOREWORD SECTOR
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Gavião, Luiz Octávio

; Gomes, Carlos Francisco S.

; Pessôa, Leonardo Antonio M.

Pesquisa Operacional

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

2024, Volume 44 elocation e2024s1

Resumo: En | Texto: En | PDF: En

https://doi.org/10.1590/0101-7438.2023.043.002024s1

14.

Curva de Aprendizagem da Mortalidade Hospitalar da Substituição da Válvula Aórtica Transcateter: Insights do Registro Nacional Brasileiro Transcateter
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Bernardi, Fernando Luiz de Melo

; Abizaid, Alexandre A.

; Brito Jr, Fábio Sândoli de

; Lemos, Pedro A.

; Siqueira, Dimytri Alexandre Alvim de

; Costa, Ricardo Alves

; Leite, Rogério Eduardo Gomes Sarmento

; Mangione, Fernanda Marinho

; Thiago, Luiz Eduardo Koenig São

; Mangione, José A.

; Lima, Valter Correia de

; Oliveira, Adriano Dourado

; Marino, Marcos Antônio

; Cardoso, Carlos José Francisco

; Caramori, Paulo R. A.

; Tumelero, Rogério

; Portela, Antenor Lages Fortes

; Prudente, Mauricio

; Henriques, Leônidas Alvarenga

; Souza, Fabio Solano

; Bezerra, Cristiano Guedes

; Prado Jr, Guy F. A.

; Freitas, Leandro Zacaris Figueiredo

; Nogueira, Ederlon Ferreira

; Meireles, George César Ximenes

; Pope, Renato Bastos

; Guerios, Enio

; Andrade, Pedro Beraldo de

; Santos, Luciano de Moura

; Marchi, Mauricio Felippi de Sá

; Fundão, Nelson Henrique Fantin

; Ribeiro, Henrique Barbosa

Arquivos Brasileiros de Cardiologia

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

2024, Volume 121 Nº 7 elocation e20230622

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

Abstract Background Robust data on the learning curve (LC) of transcatheter aortic valve replacement (TAVR) are lacking in developing countries. Objective To assess TAVR’s LC in Brazil over time. Methods We analyzed data from the Brazilian TAVR registry from 2008 to 2023. Patients from each center were numbered chronologically in case sequence numbers (CSNs). LC was performed using restricted cubic splines adjusted for EuroSCORE-II and the use of new-generation prostheses. Also, in-hospital outcomes were compared between groups defined according to the level of experience based on the CSN: 1st to 40th (initial-experience), 41st to 80th (early-experience), 81st to 120th (intermediate-experience), and over 121st (high-experience). Additional analysis was performed grouping hospitals according to the number of cases treated before 2014 (>40 and ≤40 procedures). The level of significance adopted was <0.05. Results A total of 3,194 patients from 25 centers were included. Mean age and EuroSCORE II were 80.7±8.1 years and 7±7.1, respectively. LC analysis demonstrated a drop in adjusted in-hospital mortality after treating 40 patients. A leveling off of the curve was observed after case #118. In-hospital mortality across the groups was 8.6%, 7.7%, 5.9%, and 3.7% for initial-, early-, intermediate-, and high-experience, respectively (p<0.001). High experience independently predicted lower mortality (OR 0.57, p=0.013 vs. initial experience). Low-volume centers before 2014 showed no significant decrease in the likelihood of death with gained experience, whereas high-volume centers had a continuous improvement after case #10. Conclusion A TAVR LC phenomenon was observed for in-hospital mortality in Brazil. This effect was more pronounced in centers that treated their first 40 cases before 2014 than those that reached this milestone after 2014. (LC (TAVR countries TAVRs s time 200 2023 CSNs. CSNs . (CSNs) EuroSCOREII newgeneration new generation prostheses Also inhospital hospital CSN st th initialexperience, initialexperience , (initial-experience) earlyexperience, earlyexperience early (early-experience) intermediateexperience, intermediateexperience intermediate (intermediate-experience) highexperience. highexperience high (high-experience) 201 >40 (>4 ≤4 procedures. procedures procedures) 005 0 05 <0.05 3194 3 194 3,19 2 included 80781 80 7 8 1 80.7±8. 771 7±7.1 4 118 #118 Inhospital In 86 6 8.6% 77 7.7% 59 5 9 5.9% 37 3.7 initial, initial- early, early- intermediate, intermediate- highexperience, high-experience p<0.001. p0001 p p<0.001 001 (p<0.001) OR 057 57 0.57 p0013 013 p=0.01 vs experience. experience) Lowvolume Low volume highvolume 10 #10 20 202 (CSNs (initial-experience (early-experience (intermediate-experience (high-experience >4 (> ≤ 00 <0.0 319 19 3,1 8078 80.7±8 7±7. 11 #11 8.6 7.7 5.9 3. p000 p<0.00 (p<0.001 0.5 p001 01 p=0.0 #1 > ( <0. 31 3, 807 80.7± 7±7 8. 7. 5. p00 p<0.0 (p<0.00 0. p=0. # <0 80.7 7± p0 p<0. (p<0.0 p=0 < 80. p<0 (p<0. p= p< (p<0 (p< (p

Resumo Fundamento Dados robustos sobre a curva de aprendizagem (LC) da substituição da válvula aórtica transcateter (TAVR) são escassos nos países em desenvolvimento. Objetivo Avaliar a LC da TAVR no Brasil ao longo do tempo. Métodos Analisamos dados do registro brasileiro de TAVR de 2008 a 2023. Pacientes de cada centro foram numerados cronologicamente em número sequencial de caso (NSC). A LC foi realizada usando um spline cúbico restrito ajustado para o EuroSCORE-II e o uso de próteses de nova geração. Ainda, os desfechos hospitalares foram comparados entre grupos definidos de acordo com o nível de experiência, com base no NSC: 1º ao 40º caso (experiência inicial), 41º ao 80º caso (experiência básica), 81º ao 120º caso (experiência intermediária) e 121º caso em diante (experiência alta). Análises adicionais foram conduzidas de acordo com o número de casos tratados antes de 2014 (>40 e ≤40 procedimentos). O nível de significância adotado foi p <0,05. Resultados Foram incluídos 3194 pacientes de 25 centros. A idade média foi 80,7±8,1 anos e o EuroSCORE II médio foi 7±7,1. A análise da LC demonstrou uma queda na mortalidade hospitalar ajustada após o tratamento de 40 pacientes. Um patamar de nivelamento na curva foi observado após o caso 118. A mortalidade hospitalar entre os grupos foi 8,6%, 7,7%, 5,9%, e 3,7% para experiência inicial, básica, intermediária e alta, respectivamente (p<0,001). A experiência alta foi preditora independente de mortalidade mais baixa (OR 0,57, p=0,013 vs. experiência inicial). Centros com baixo volume de casos antes de 2014 não mostraram uma redução significativa na probabilidade de morte com o ganho de experiência, enquanto centros com alto volume de casos antes de 2014 apresentaram uma melhora contínua após o caso de número 10. Conclusão Observou-se um fenômeno de LC para a mortalidade hospitalar do TAVR no Brasil. Esse efeito foi mais pronunciado em centros que trataram seus 40 primeiros casos antes de 2014 que naqueles que o fizeram após 2014. (LC (TAVR desenvolvimento tempo 200 2023 NSC. NSC . (NSC) EuroSCOREII geração Ainda º inicial , inicial) básica básica) alta. alta) 201 >40 (>4 ≤4 procedimentos. procedimentos procedimentos) 005 0 05 <0,05 319 2 80781 80 7 8 1 80,7±8, 771 7±7,1 4 118 86 6 8,6% 77 7,7% 59 5 9 5,9% 37 3 3,7 p<0,001. p0001 p<0,001 001 (p<0,001) OR 057 57 0,57 p0013 013 p=0,01 vs inicial. 10 Observouse Observou se 20 202 (NSC >4 (> ≤ 00 <0,0 31 8078 80,7±8 7±7, 11 8,6 7,7 5,9 3, p000 p<0,00 (p<0,001 0,5 p001 01 p=0,0 > ( <0, 807 80,7± 7±7 8, 7, 5, p00 p<0,0 (p<0,00 0, p=0, <0 80,7 7± p0 p<0, (p<0,0 p=0 < 80, p<0 (p<0, p= p< (p<0 (p< (p

https://doi.org/10.36660/abc.20230622

15.

Diretriz sobre Diagnóstico e Tratamento da Cardiomiopatia Hipertrófica – 2024 202 20 2
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Fernandes, Fabio

; Simões, Marcus V.

; Correia, Edileide de Barros

; Marcondes-Braga, Fabiana Goulart

; Coelho-Filho, Otavio Rizzi

; Mesquita, Cláudio Tinoco

; Mathias Junior, Wilson

; Antunes, Murillo de Oliveira

; Arteaga-Fernández, Edmundo

; Rochitte, Carlos Eduardo

; Ramires, Felix José Alvarez

; Alves, Silvia Marinho Martins

; Montera, Marcelo Westerlund

; Lopes, Renato Delascio

; Oliveira Junior, Mucio Tavares de

; Scolari, Fernando Luis

; Avila, Walkiria Samuel

; Canesin, Manoel Fernandes

; Bocchi, Edimar Alcides

; Bacal, Fernando

; Moura, Lidia Zytynski

; Saad, Eduardo Benchimol

; Scanavacca, Mauricio Ibrahim

; Valdigem, Bruno Pereira

; Cano, Manuel Nicolas

; Abizaid, Alexandre Antonio Cunha

; Ribeiro, Henrique Barbosa

; Lemos Neto, Pedro Alves

; Ribeiro, Gustavo Calado de Aguiar

; Jatene, Fabio Biscegli

; Dias, Ricardo Ribeiro

; Beck-da-Silva, Luis

; Rohde, Luis Eduardo Paim

; Bittencourt, Marcelo Imbroinise

; Pereira, Alexandre da Costa

; Krieger, José Eduardo

; Villacorta Junior, Humberto

; Martins, Wolney de Andrade

; Figueiredo Neto, José Albuquerque de

; Cardoso, Juliano Novaes

; Pastore, Carlos Alberto

; Jatene, Ieda Biscegli

; Tanaka, Ana Cristina Sayuri

; Hotta, Viviane Tiemi

; Romano, Minna Moreira Dias

; Albuquerque, Denilson Campos de

; Mourilhe-Rocha, Ricardo

; Hajjar, Ludhmila Abrahão

; Brito Junior, Fabio Sandoli de

; Caramelli, Bruno

; Calderaro, Daniela

; Farsky, Pedro Silvio

; Colafranceschi, Alexandre Siciliano

; Pinto, Ibraim Masciarelli Francisco

; Vieira, Marcelo Luiz Campos

; Danzmann, Luiz Claudio

; Barberato, Silvio Henrique

; Mady, Charles

; Martinelli Filho, Martino

; Torbey, Ana Flavia Malheiros

; Schwartzmann, Pedro Vellosa

; Macedo, Ariane Vieira Scarlatelli

; Ferreira, Silvia Moreira Ayub

; Schmidt, Andre

; Melo, Marcelo Dantas Tavares de

; Lima Filho, Moysés Oliveira

; Sposito, Andrei C.

; Brito, Flávio de Souza

; Biolo, Andreia

; Madrini Junior, Vagner

; Rizk, Stephanie Itala

; Mesquita, Evandro Tinoco

Arquivos Brasileiros de Cardiologia

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

2024, Volume 121 Nº 7 elocation e202400415

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

https://doi.org/10.36660/abc.20240415

Exibindo

itens por página

Página de 38 Próxima

Selecione um ou mais resultados

Todos Ordem alfabética

Resultados

Gráfico comparativo Download CSV

Visualizar estatísticas de

Enviar resultado

E-mail do(s) destinatários*

Utilize ; (ponto e vírgula) para mais de um e-mail.

Enviar por e-mail

Esta página

Registros selecionados

Todos os registros (max. 300)

Alterar remetente, assunto e comentários

Seu email

Assunto

Comentários

Alterar remetente, assunto e comentários

Exportar resultados

Formato de exportação:

RIS (para EndNote, ProCite, Reference Manager, RefWorks, Citavi, etc.)

BibTeX

Citação

CSV (para Excel, etc)

Exportar:

Esta página

Itens selecionados

Todos os registros (max. 2000)

Mostrar mais

Sem resultados

Não foram encontrados documentos para sua pesquisa

Glossário e ajuda para busca

Você pode enriquecer sua busca de uma forma muito simples. Use os índices de pesquisa combinados com os conectores (AND ou OR) e especifique cada vez mais sua busca.

Por exemplo, se você deseja buscar artigos sobre
casos de dengue no Brasil em 2015, use:
ti:dengue and publication_year:2015 and aff_country:Brasil

Veja abaixo a lista completa de índices de pesquisa que podem ser usados:

Cód. do Índice	Elemento
ti	título do artigo
au	autor
kw	palavras-chave do artigo
subject	assunto (palavras do título, resumo e palavras-chave)
ab	resumo
ta	título abreviado da revista (ex. Cad. Saúde Pública)
journal_title	título completo da revista (ex. Cadernos de Saúde Pública)
la	código do idioma da publicação (ex. pt - Português, es - Espanhol)
type	tipo do documento
pid	identificador da publicação
publication_year	ano de publicação do artigo
sponsor	financiador
aff_country	código do país de afiliação do autor
aff_institution	instituição de afiliação do autor
volume	volume do artigo
issue	número do artigo
elocation	elocation
doi	número DOI
issn	ISSN da revista
in	código da coleção SciELO (ex. scl - Brasil, col - Colômbia)
use_license	código da licença de uso do artigo

SciELO - Scientific Electronic Library Online
Rua Dr. Diogo de Faria, 1087 – 9º andar – Vila Clementino 04037-003 São Paulo/SP - Brasil
Email: scielo@scielo.org

Todo o conteúdo de www.scielo.org, exceto onde está identificado, está licenciado sob uma Licença Creative Commons.
saiba mais »