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Abstract Background Heart rate (HR) has shown prognostic value in patients with heart failure with reduced ejection fraction (HFrEF) and sinus rhythm. However, the method of measurement is debated in the literature. Objectives To compare HR on Holter with 3 resting electrocardiograms (ECG1, ECG2, and ECG3) in patients with HFrEF and sinus rhythm. Methods This was a cross-sectional study with 135 patients with heart failure with ejection fraction ≤ 40% and sinus rhythm. HR was assessed by ECG and Holter. Analyses included intraclass correlation coefficient (ICC), robust regression, root mean squared error, Bland-Altman, and area under the receiver operating characteristic (ROC) curve. A significance level of 0.05 and Bonferroni-Holm adjustment were adopted to minimize type I errors. Results The median [interquartile range] age and ejection fraction were 65 years [16] and 30% [11], respectively. The ICC of the 3 ECGs was 0.922 (95% confidence interval: 0.892; 0.942). The robust regression coefficients for ECG1 and ECG3 were 0.20 (95% confidence interval: 0.12; 0.29) and 0.21 (95% confidence interval: 0.06; 0.36). The robust R2 was 0.711 (95% confidence interval: 0.628; 0.76). In the Bland-Altman agreement analysis, the limits of agreement were −17.0 (95% confidence interval: −19.0; −15.0) and 32.0 (95% confidence interval: 30.0; 34.0). The area under the ROC curve was 0.896 (95% confidence interval: 0.865; 0.923). Conclusion The HR on ECG showed high agreement with the HR on Holter, validating its clinical use in patients with HFrEF and sinus rhythm. However, agreement was suboptimal in one third of patients with HR below 70 bpm on ECG; thus, 24-hour Holter monitoring should be considered in this context. (HR (HFrEF rhythm However literature ECG1, (ECG1 ECG2 crosssectional cross sectional 13 40 ICC, , (ICC) error BlandAltman, BlandAltman Bland Altman, Altman (ROC 005 0 05 0.0 BonferroniHolm Bonferroni Holm errors interquartile range 6 16 [16 30 11, 11 [11] respectively 0922 922 0.92 95% 95 (95 interval 0.892 0892 892 0.942. 0942 0.942 . 942 0.942) 020 20 0.2 0.12 012 12 0.29 029 29 021 21 0.06 006 06 0.36. 036 0.36 36 0.36) R 0711 711 0.71 0.628 0628 628 0.76. 076 0.76 76 0.76) analysis 170 17 −17. −19.0 190 19 −15.0 150 15 320 32 32. 30.0 300 34.0. 340 34.0 34 34.0) 0896 896 0.89 0.865 0865 865 0.923. 0923 0.923 923 0.923) 7 thus 24hour hour 24 context (ECG 1 4 (ICC 00 0. [1 [11 092 92 0.9 9 (9 089 89 094 0.94 94 02 2 0.1 01 03 0.3 071 71 0.7 0.62 062 62 07 −17 −19. −15. 30. 34. 0.8 0.86 086 86 [ 09 ( 08 8 0.6 −1 −19 −15 −

Resumo Fundamento A frequência cardíaca (FC) na insuficiência cardíaca com fração de ejeção reduzida (ICFEr) e ritmo sinusal apresenta valor prognóstico. Entretanto, o método de mensuração é debatido na literatura. Objetivos Comparar em pacientes com ICFEr e ritmo sinusal a FC no Holter com três eletrocardiogramas de repouso: ECG1, ECG2 e ECG3. Metodologia Estudo transversal com 135 pacientes portadores de insuficiência cardíaca com fração de ejeção ≤ 40% e ritmo sinusal. A FC foi avaliada por ECG e Holter. Análises incluíram o coeficiente de correlação intraclasse (CCI), regressão robusta, raiz do erro quadrático médio, Bland-Altman e a área sobre a curva ROC. Adotou-se nível de significância de 0,05 e o ajuste de Bonferroni-Holm para minimizar erros tipo I. Resultados As medianas [intervalo interquartil] de idade e fração de ejeção foram de 65 anos [16] e 30% [11], respectivamente. O CCI dos 3 ECG foi de 0,922 (intervalo de confiança de 95%: 0,892; 0,942). Os coeficientes de regressão robusta para ECG1 e ECG3 foram 0,20 (intervalo de confiança de 95%: 0,12; 0,29) e 0,21 (intervalo de confiança de 95%: 0,06; 0,36). O R2 robusto foi de 0,711 (intervalo de confiança de 95%: 0,628; 0,76). Na análise de concordância de Bland-Altman, os limites de concordância foram de −17,0 (intervalo de confiança de 95%: −19,0; −15,0) e 32,0 (intervalo de confiança de 95%: 30,0; 34,0). A área sob a curva ROC foi de 0,896 (intervalo de confiança de 95%: 0,865; 0,923). Conclusão A FC do ECG mostrou alta concordância com a FC do Holter, validando seu uso clínico em pacientes com ICFEr e ritmo sinusal. Contudo, a concordância foi subótima em um terço dos pacientes com FC inferior a 70 bpm pelo ECG, devendo ser considerada a realização de Holter neste contexto. (FC (ICFEr prognóstico Entretanto literatura repouso 13 40 CCI, , (CCI) médio BlandAltman Bland Altman Adotouse Adotou se 005 0 05 0,0 BonferroniHolm Bonferroni Holm I intervalo interquartil 6 16 [16 30 11, 11 [11] respectivamente 0922 922 0,92 95% 95 0,892 0892 892 0,942. 0942 0,942 . 942 0,942) 020 20 0,2 0,12 012 12 0,29 029 29 021 21 0,06 006 06 0,36. 036 0,36 36 0,36) R 0711 711 0,71 0,628 0628 628 0,76. 076 0,76 76 0,76) BlandAltman, Altman, 170 17 −17, −19,0 190 19 −15,0 150 15 320 32 32, 30,0 300 34,0. 340 34,0 34 34,0) 0896 896 0,89 0,865 0865 865 0,923. 0923 0,923 923 0,923) Contudo 7 contexto 1 4 (CCI 00 0, [1 [11 092 92 0,9 9 089 89 094 0,94 94 02 2 0,1 01 03 0,3 071 71 0,7 0,62 062 62 07 −17 −19, −15, 30, 34, 0,8 0,86 086 86 [ 09 08 8 0,6 −1 −19 −15 −

https://doi.org/10.36660/abc.20230771

Performance Study of Ni/Si-MCM-41 Catalysts, Synthesized with Different Silica Sources, and Their Application on Methane Dry Reform to Produce Green Hydrogen Ni/SiMCM41 NiSiMCM41 NiSiMCM Ni/Si MCM 41 Ni Si Ni/Si-MCM-4 Catalysts Sources SiMCM41 SiMCM Ni/SiMCM4 NiSiMCM4 NiSi 4 Ni/Si-MCM- SiMCM4 Ni/SiMCM Ni/Si-MCM
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Cazula, Bárbara B.

; Fonseca, Renata O. da

; Marinho, André Luiz A.

; Noronha, Fábio B.

; Arroyo, Pedro Augusto

; Yamamoto, Carlos I.

; Brackmann, Rodrigo

; Alves, Helton José

Journal of the Brazilian Chemical Society

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2024, Volume 35 Nº 3 elocation e-20230133

Resumo: En | Texto: En | PDF: En

The present work carried out an extensive and deepened study regarding the physico-chemical characteristics of two Si-MCM-41-type supports, synthesized employing two distinct silica precursors, tetraethyl orthosilicate (TEOS) and rice husk ash (RHS), with the dispersion of nickel on the surface of the catalytic support. The direct influence of the active phase dispersion was analyzed, making a relationship with the formation of coke and with its performance on methane dry reform (DRM). The catalysts were prepared with 5, 10, and 20% (m/m) of Ni by wet impregnation method (with excess solvent), calcined at 800 ºC for 6 h, and characterized by the techniques of scanning electron microscopy and energy dispersive spectroscopy (SEM/ EDS), transmission electron microscopy (TEM), Brunauer-Emmett-Teller (BET)/Barret-Joyer-Halenda (BJH), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), temperature-programmed ammonia desorption (TPD-NH3), and H2-temperature-programmed reduction (TPR). The DRM experiments were carried out at 800 °C for 24 h with a 1:1 CH4:CO2 molar ratio. Analyzes of gaseous products were performed in gas chromatography (GC) and the coke produced was estimated by temperature-programmed oxidation (TPO). The best reaction results were obtained for catalysts with 20% nickel, which were selective and stable within 24 h of reaction. Comparing the TEOS and RHS catalysts for 20% Ni, the DRM results were very similar. The catalysts on RHS support demonstrated a significant low formation of coke, which can be considered negligible in a 24 h reaction. physicochemical physico chemical SiMCM41type SiMCMtype Si MCM 41 type supports precursors (TEOS RHS, , (RHS) analyzed DRM. . (DRM) 5 10 20 m/m mm m (m/m solvent, solvent solvent) 80 SEM/ SEM (SEM EDS, EDS EDS) TEM, TEM (TEM) BrunauerEmmettTeller Brunauer Emmett Teller BET/BarretJoyerHalenda BETBarretJoyerHalenda BET /Barret Joyer Halenda Barret BJH, BJH (BJH) Xray X ray XRD, XRD (XRD) FTIR, FTIR (FTIR) temperatureprogrammed temperature programmed TPDNH3, TPDNH3 TPDNH TPD NH3 NH (TPD-NH3) H2temperatureprogrammed Htemperatureprogrammed H2 H TPR. TPR (TPR) C 2 11 1 1: CH4CO2 CHCO CH4 CO2 CH CO CH4:CO ratio GC (GC TPO. TPO (TPO) similar SiMCM 4 (RHS (DRM 8 (TEM BarretJoyerHalenda (BJH (XRD (FTIR (TPD-NH3 (TPR CH4CO (TPO (TPD-NH

https://doi.org/10.21577/0103-5053.20230133

Prediction of body weight of Brown Alpine goats by measuring body volume
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Oliveira, N.M.

; Gurgel, A.L.C.

; Fonseca, I.

; Lopes, J.F.

; Difante, G.S.

; Ítavo, L.C.V.

; Araújo, M.J.

; Dias-Silva, T.P.

; Carvalho, A.A.

; Chay-Canul, A.J.

Arquivo Brasileiro de Medicina Veterinária e Zootecnia

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2024, Volume 76 Nº 4 elocation e13170

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO Objetivou-se estimar o peso corporal (PC) de cabras da raça Alpina por meio da medida do volume corporal (VC). Foram utilizadas 132 informações, com medições de PC, comprimento corporal (CC) e perímetro torácico (PT), de 22 cabras avaliadas quinzenalmente, entre março e maio de 2023. Com base nessas informações, o VC dos animais foi calculado. Três modelos matemáticos foram avaliados - um modelo linear, um modelo quadrático e um modelo exponencial - com a medição do VC como único preditor. A qualidade de ajuste das equações foi avaliada usando-se o coeficiente de determinação (R2), o erro do quadrado médio (EQM) e a raiz do EQM (REQM). A capacidade preditiva dos modelos foi avaliada por meio de validação cruzada k-fold (k = 10). Foi observada uma alta correlação positiva entre o PC e o PT (r = 0,95) e o CC (r = 0,94). A correlação entre o PC e o VC foi maior do que as outras correlações (r = 0,98). O modelo linear mostrou os menores valores de EQM (9,49) e REQM (3,08). Na validação cruzada, os modelos linear e quadrático apresentaram estimativas do PC médio e do desvio padrão desse peso semelhantes aos dados reais e altos valores de R2 (0,95) dos dados predistos em relação aos observados. A análise do coeficiente de correlação e concordância (CCC) também mostrou que esses modelos têm precisão e acurácia (CCC > 0,95). Assim, os modelos linear e quadrático estimam o peso corporal de cabras da raça Alpina com precisão e acurácia. Objetivouse Objetivou se (PC VC. . (VC) 13 informações (CC PT, , (PT) 2 quinzenalmente 2023 calculado preditor usandose usando R2, R (R2) (EQM REQM. (REQM) kfold k fold 10. 10 10) r 0,95 095 0 95 0,94. 094 0,94 94 0,94) 0,98. 098 0,98 98 0,98) 9,49 949 9 49 (9,49 3,08. 308 3,08 3 08 (3,08) (0,95 observados CCC 0,95. Assim (VC 1 (PT 202 (R2 (REQM 0,9 09 9,4 4 (9,4 30 3,0 (3,08 (0,9 20 (R 0, 9, (9, 3, (3,0 (0, (9 (3, (0 ( (3

ABSTRACT The objective was to estimate the body weight (BW) of Brown Alpine goats by means of body volume (BV) measurements. We used 132 pieces of information with measurements of BW, body length (BL) and thoracic perimeter (TP) from 22 goats evaluated fortnightly, between March and May 2023. Based on this information, the BV of the animals was calculated. Three mathematical models were evaluated - a linear model, a quadratic model, and an exponential model - with the measurement of BV. The goodness of fit of the equations was evaluated using the coefficient of determination (R2), mean square error (MSE) and root of the MSE (RMSE). The predictive ability of the models was evaluated by k-fold cross-validation (k = 10). A high positive correlation between BW and TP (r = 0.95) and BL (r = 0.94) was observed. The correlation between BW and BV was higher than the other correlations (r = 0.98). The linear model showed the lowest values of MSE (9.49) and RMSE (3.08). In the cross-validation, the linear and quadratic models presented estimates of the mean BW and the standard deviation of this weight similar to the real data, and high R2 values (0.95) of the data predicted by the observed ones. The analysis of the coefficient of correlation and concordance (CCC) also showed that these models have accuracy and precision (CCC > 0.95). Thus, the linear and quadratic models estimate the body weight of Brown Alpine goats with precision and accuracy. (BW (BV 13 (BL (TP 2 fortnightly 2023 calculated R2, R , (R2) (MSE RMSE. . (RMSE) kfold k fold crossvalidation cross validation 10. 10 10) r 0.95 095 0 95 0.94 094 94 0.98. 098 0.98 98 0.98) 9.49 949 9 49 (9.49 3.08. 308 3.08 3 08 (3.08) crossvalidation, validation, (0.95 ones CCC 0.95. Thus 1 202 (R2 (RMSE 0.9 09 9.4 4 (9.4 30 3.0 (3.08 (0.9 20 (R 0. 9. (9. 3. (3.0 (0. (9 (3. (0 ( (3

https://doi.org/10.1590/1678-4162-13170

Mato Grosso do Sul on the Growth Route: an investigation into the potentialities driven by the Bioceanic Route
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Constantino, Michel

; Costa, Reginaldo Brito da

; Bolson, Daniel Silva

; Mendes, Dany Rafael Fonseca

Interações (Campo Grande)

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Out 2023, Volume 24 Nº 4 elocation e2444195

Resumo: Es En Pt | Texto: Es En Pt | PDF: Es | PDF: En | PDF: Pt

Resumen Este artículo tuvo como objetivo investigar la relación entre el potencial de crecimiento económico de Mato Grosso do Sul con la implementación de la Ruta Bioceânica. Utilizando estudios realizados y publicados desde 2015, el análisis estructura y define las principales potencialidades en el ámbito macroeconómico y sectorial para Mato Grosso do Sul. Los resultados definieron cinco puntos de análisis: i. Crecimiento económico acelerado; ii. Expansión del comercio internacional; iii. Inversión en infraestructura; IV. Desarrollo de nuevas cadenas productivas y v. Fortalecimiento de la posición estratégica del estado. Se elaboró un análisis de radary la distribución de probabilidad de impacto en cada punto enumerado después de la implementación definitiva de la Ruta, que podría llevar al estado de Mato Grosso do Sul a la Ruta del Crecimiento. Bioceânica 2015 i acelerado ii internacional iii infraestructura IV v 201 20 2

Abstract This article aimed to investigate the relationship between the potential of economic growth in Mato Grosso do Sul with the implementation of the Bioceânica Route. Using studies carried out and published since 2015, the analysis structures and defines the main potentialities in the macroeconomic and sectoral scope for Mato Grosso do Sul. The results defined five points of analysis: i. Accelerated economic growth; ii. Expansion of international trade; iii. Investment in infrastructure; iv. Development of new production chains and v. Strengthening the strategic position of the state. A radar analysis and the probability distribution of impact on each point listed after the definitive implementation of the Route was prepared, which could lead the state of Mato Grosso do Sul to the Route of Growth. 2015 i ii trade iii infrastructure iv v prepared Growth 201 20 2

Resumo O presente artigo objetivou investigar a relação entre as potencialidades do crescimento econômico de Mato Grosso do Sul com a implementação da Rota Bioceânica. Utilizando dos estudos realizados e publicados desde 2015, a análise estrutura e define as principais potencialidades no âmbito macroeconômico e setorial para Mato Grosso do Sul. Os resultados definiram cinco pontos de análise: i. Crescimento económico acelerado; ii. Ampliação do comércio internacional; iii. Investimento em infraestrutura; iv. Desenvolvimento de novas cadeias produtivas e v. Fortalecimento da posição estratégica do estado. Foi elaborado uma análise de radar e a distribuição de probabilidade de impacto em cada ponto elencado após a implementação da Rota em definitivo, o que pode levar o estado de Mato Grosso do Sul para a Rota do Crescimento. Bioceânica 2015 i acelerado ii internacional iii infraestrutura iv v definitivo 201 20 2

https://doi.org/10.20435/inter.v24i4.4195

Cross-cultural differences in beliefs about emotions: A comparison between Brazilian and British participants Crosscultural Cross cultural emotions
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Fonseca, Rodrigo G.

; Marques, Pamela I. S.

; Costa, Fernanda F. da

; Landeira-Fernandez, Jesus

; Rimes, Katharine A.

; Mograbi, Daniel C.

Jornal Brasileiro de Psiquiatria

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2023, Volume 72 Nº 3 Páginas 152 - 158

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

ABSTRACT Objective: Perfectionist beliefs about emotions impact the experience and expression of emotions, being linked to increased levels of depression and anxiety. Given the influence of culture in the representation and expression of emotion, it is possible that beliefs vary across countries, but few empirical studies have been conducted on the theme. This study aims to compare Brazilian and British samples regarding their beliefs about emotional experience and expression. Methods: The current study compared a total of 960 Brazilian and British participants, with the samples having a similar profile in terms of age, gender and ethnicity. Participants answered online the Generalized Anxiety Disorder (GAD-7), Patient Health Questionnaire (PHQ-9), and Beliefs about Emotions Scale (BES). This study aims to compare Brazilian and British samples with regard to beliefs about emotional experience and expression. Results: Significant differences between samples were found for beliefs about emotions. As hypothesized, Brazilians scored lower on unhelpful beliefs about emotions, except for beliefs about experiencing negative feelings and emotional control. Differences in total BES scores remained even after the inclusion of depression and anxiety as covariates. Conclusions: Results suggest higher endorsement of perfectionist beliefs in a European versus a Latin American context, but highlight that this pattern depends on the specific beliefs being studied. These differences should be considered when working with people from different cultural backgrounds and developing cultural adaptations for clinical interventions and psychopathology models. Objective emotion countries theme Methods 96 participants age ethnicity GAD7, GAD7 GAD 7 , (GAD-7) PHQ9, PHQ9 PHQ 9 (PHQ-9) BES. . (BES) hypothesized control covariates Conclusions context studied models (GAD-7 (PHQ-9 (BES (GAD- (PHQ- (GAD (PHQ

RESUMO Objetivo: Crenças perfeccionistas sobre emoções afetam a experiência e expressão de emoções, estando relacionadas a níveis aumentados de depressão e ansiedade. Dada a influência da cultura na representação e expressão de emoções, é possível que as crenças variem entre os países, mas poucos estudos empíricos foram realizados sobre o tema. Este estudo tem o objetivo de comparar amostras brasileiras e britânicas em relação às suas crenças sobre a experiência emocional e expressão. Métodos: O presente estudo comparou um total de 960 participantes brasileiros e britânicos, com as amostras tendo um perfil semelhante em termos de idade, gênero e etnia. Os participantes responderam on-line à Escala de Ansiedade Generalizada (GAD-7), ao Questionário de Saúde do Paciente (PHQ-9) e à Escala de Crenças sobre Emoções (BES). Resultados: Foram encontradas diferenças significativas entre as amostras em relação às crenças sobre emoções. Como hipotetizado, os brasileiros obtiveram pontuações mais baixas em crenças prejudiciais sobre emoções, exceto nas crenças sobre experienciar sentimentos negativos e controle emocional. As diferenças nos escores totais da BES permaneceram mesmo após a inclusão de depressão e ansiedade como covariáveis. Conclusões: Os resultados sugerem maior endosso de crenças perfeccionistas em um contexto europeu, em comparação com um contexto latino-americano, mas destacam que esse padrão depende das crenças específicas estudadas. Essas diferenças devem ser consideradas ao trabalhar com pessoas de diferentes origens culturais e no desenvolvimento de adaptações culturais para intervenções clínicas e modelos de psicopatologia. Objetivo países tema Métodos 96 britânicos idade etnia online on line GAD7, GAD7 GAD 7 , (GAD-7) PHQ9 PHQ 9 (PHQ-9 BES. . (BES) Resultados hipotetizado covariáveis Conclusões europeu latinoamericano, latinoamericano latino americano, americano latino-americano estudadas psicopatologia (GAD-7 (PHQ- (BES (GAD- (PHQ (GAD

https://doi.org/10.1590/0047-2085000000423

A long fruiting series of Myrcia neoregeliana (Myrtaceae) shows the maintenance of seasonal resource supplies for dispersal by birds Myrtaceae (Myrtaceae
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Gomes, M. T. D.

; Bezerra-Silva, A.

; Morais, D. B. B. A.

; Souza, I. P.

; Lobo, L. S.

; Oliveira, J. C. de

; Menezes, I. S.

; Fonseca, R. B. S.

; Moraes, A. C. S.

; Moura, A. C.

; Funch, L. S.

Brazilian Journal of Biology

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2023, Volume 83 elocation e275839

Resumo: En | Texto: En | PDF: En

https://doi.org/10.1590/1519-6984.275839

Evaluation of nutritional composition of flour residue of mangaba processing
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Vasconcelos, K. M. C. S. G.

; Costa, J. G.

; Pavão, J. M. S. J.

; Fonseca, S. A.

; Miranda, P. R. B.

; Matos-Rocha, T. J.

; Freitas, J. D.

; Sousa, J. S.

; Melo, I. S. V.

; Santos, A. F.

Brazilian Journal of Biology

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2023, Volume 83 elocation e248931

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo Dentre as diversas frutas a mangaba (Hancornia speciosa Gomes), despertou interesse de produtores e consumidores devido às suas características sensoriais atrativas e propriedades benéficas à saúde (elevado valor nutricional e presença de substâncias bioativas), assim, o trabalho avaliar os fatores nutricionais do resíduo da farinha de processamento de mangaba que é desprezado pela indústria alimentícia e, a influência da temperatura na sua produção. O resíduo de processamento da mangaba foi dividido em dois lotes, sendo um deles utilizado para as análises in natura (amostra controle) e o outro para a confecção da farinha que foi seca a 50 °C, e dividida em dois lotes: tratamento A (farinha com torras a 110 °C e 130 °C) e no tratamento B (farinha oriunda da secagem a 50 °C). Analisou-se as características nutricionais de farinhas considerando os parâmetros químicos: pH, acidez total titulável e sólidos solúveis, além da determinação do teor de umidade, lipídios totais, fibra alimentar total e cinzas, valor energético total, atividade antioxidante, triagem fitoquímica, quantificação de compostos fenólicos e flavonoides, bem como as propriedades funcionais tecnológicas (índice de absorção de água (IAA), índice de solubilidade em água (ISA), índice de absorção de leite (IAL) e índice de solubilidade em leite (ISL) e índice de absorção de óleo (IAO). Na análise foi inferido que os compostos bioativos presentes nos extratos não possuem propriedades significativas de agir como sequestradores de radicais livres. O tratamento térmico, realizado na farinha de resíduos de processamento de mangaba, influenciou nos dados dos fatores nutricionais e das propriedades de absorção e solubilidade, os quais apresentaram diferenças estatísticas. Estes resultados credenciam a farinha como uma alternativa viável para o enriquecimento energético de dietas, contribuindo para o desenvolvimento de novos produtos, a redução do descarte desses resíduos e consequentemente para a minimização do impacto ambiental.

Abstract Among several fruits, mangaba (Hancornia speciosa Gomes), it aroused the interest of producers and consumers due to its attractive sensory characteristics and health beneficial properties (high nutritional value and presence of bioactive substances), thus, this work evaluates the nutritional factors of the flour residue of mangaba processing that is despised by the food industry, and the influence of temperature on its production. The mangaba processing residue was splited in two main groups: in natura sample (control), and other for preparation of flour that was dried at 50 °C and divided into two other groups: treatment A (flour with roasts at 110 °C and 130 °C) and treatment B (flour from drying at 50 °C). The nutritional characteristics of flours were analyzed considering the chemical parameters: pH, titratable total acidity and soluble solids, in addition to the determination of moisture content, total lipids, total dietary fiber and ash, total energy value, antioxidant activity, phytochemical screening, quantification of phenolic compounds and flavonoids, as well as technological functional properties (water absorption index (WAI), water solubility index (WSI), milk absorption index (MAI) and milk solubility index (MSI) and oil absorption index (OAI). The results showed that the bioactive compounds present in the extracts do not have significant properties of acting as free radical kidnappers. The heat treatment, performed in the flour of mangaba processing residues, influenced the nutritional factors and properties of absorption and solubility, which showed statistical differences. These results show that the flour is a viable alternative for the energy enrichment of diets, contributing to the development of new products, the reduction of the disposal of these residues and consequently to the minimization of the environmental impact.

https://doi.org/10.1590/1519-6984.248931 116 downloads

Spatial distribution of antimicrobial resistance of extra-intestinal clinical Escherichia coli isolated from poultry farms in western provinces of Cuba
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Ley-García, Oshin

; Abreu Jorge, Yandy

; Masdeus-Fonseca, Virginia

; Pinto-Morales, Patricio

; Montano-Valle, Damarys de las N.

; Percedo Abreu, María I.

; Espinosa, Ivette

; Alfonso, Pastor

Revista de Salud Animal

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2023, Volume 45 elocation e08

Resumo: Es En | Texto: Es En | PDF: Es | PDF: En

RESUMEN La resistencia antimicrobiana (RAM) es una preocupación mundial y una amenaza para la salud pública global. Por otra parte, Escherichia coli ha marcado una forma significativa en la evolución de la RAM. El presente estudio tuvo como objetivo caracterizar el patrón espacial de la RAM en aislados extraintestinales de E. coli procedentes de aves comerciales de provincias occidentales de Cuba. Los datos del estudio abarcaron de enero del 2014 a diciembre del 2017. El análisis de tendencias y la descripción exploratoria se realizó con el lenguaje de programación de R versión 4.0.4. Para el análisis espacial se utilizó ArcGIS 10.4 mediante el método de estimación de densidad de Kernel y salida cartográfica. Se observaron tendencias al incremento en la frecuencia de resistencia durante el periodo de estudio. La densidad de Kernel indicó que la RAM se distribuyó espacialmente en toda la región geográfica de estudio, aunque la mayor densidad (valores altos) de RAM se localizó mayoritariamente en municipios de la provincia Artemisa. Se identificaron áreas de riesgo significativamente mayor y menor de RAM en el Sudeste y Norte de la región, respectivamente. Por último, la identificación de la distribución espacial y la superficie de riesgo relativo de resistencia antimicrobiana de E. coli procedente de granjas avícolas en Cuba es un paso importante que contribuye a optimizar las prácticas de administración de antimicrobianos en la región occidental. Esto permite mejorar las medidas sanitarias preventivas y las estrategias de control para evitar enfermedades y aumentar la vigilancia epidemiológica.

ABSTRACT Antimicrobial resistance (AMR) is a worldwide concern and a threat to global public health. On the other hand, Escherichia coli has played a significant role in the evolution of AMR. The current study aimed to characterise the spatial pattern of AMR of extra-intestinal clinical E. coli isolated from commercial poultry in western provinces of Cuba. Data for the study covered January-2014 to December-2017. Trend analysis and exploratory description were carried out using R environment 4.0.4. ArcMap 10.4 was used for the spatial analysis by the Kernel Density Estimation method and visualisation map. Incremental trends in the frequency of resistance were observed during the study period. Kernel Density indicated that AMR was spatially distributed across the whole geographical region under study, although the highest density (high values) of AMR was located mainly in municipalities of Artemisa province. Areas of significantly higher and lower risk of AMR were identified in the Southeast and North of the region, respectively. Finally, the identification of the spatial distribution and relative risk surface of E. coli antimicrobial resistance from poultry farms in Cuba is a major step that contributes to optimise antimicrobial stewardship practices across the western region. This allows for improved preventive health measures and control strategies to prevent diseases and increase epidemiological surveillance.

Physicochemical, microbiological and parasitological analysis of water for human consumption in a quilombola community in Alagoas
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Correia, M. S.

; Santos, E. N. A.

; Magalhães, P. K. A.

; Santos, A. M.

; Messias, M. I. C. S. de

; Santos Júnior, J. C.

; Carvalho Neto, A. P. M.

; Souza, M. A.

; Fonseca, S. A.

; Ferreira Júnior, G. C.

; Cavalcanti, M. G. S.

; Costa, J. G.

; Miranda, P. R. B.

; Rocha, T. J. M.

Brazilian Journal of Biology

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2022, Volume 82 elocation e260905

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo A água é o recurso natural indispensável a todos os seres vivos. Para consumo humano, deve ser potável, de modo a não oferecer risco à saúde, podendo ser usada para ingestão, preparação de alimentos e higiene pessoal. Sabendo dessa importância, este estudo teve como objetivo realizar análises físico-químicas, microbiológicas e parasitológicas da água para consumo humano em uma comunidade quilombola de Alagoas. Foi realizado um estudo transversal, do tipo experimental e quantitativo, realizado na comunidade quilombola de Santa Luzia do Norte-AL, entre janeiro a dezembro de 2019. Foram analisados os parâmetros físico-químico de cloro residual, turbidez, fluoreto, fluoretação, cor e pH, as análises microbiológicas foram baseadas na pesquisa de coliformes totais e termotolerantes (E. coli) e as análise parasitológicas foram realizadas com base na pesquisa de protozoários e helmintos intestinais. E a pesquisa de protozoários oportunistas pelo método de Ziehl-Neelsen modificado. Foi observado alguns parâmetros físico-químicos (turbidez e pH) fora dos limites exigidos pelo Ministério da Saúde, e a presença de coliformes totais em algumas das amostras analisadas (17,85%), caracterizando esta comunidade em situação de risco relacionado às doenças de veiculação hídrica. As amostras analisadas não apresentaram formas infectantes das espécies parasitárias. Em relação às variáveis avaliadas, os resultados encontrados demonstraram que a falta de saneamento básico adequado afeta a qualidade da água utilizada para consumo humano pela população quilombola de Santa Luzia do Norte-AL.

Abstract Water is the indispensable natural resource for all living beings. For human consumption, it must be potable, so as not to pose a risk to health, and can be used for ingestion, food preparation and personal hygiene. Knowing this importance, this study aimed to carry out physical-chemical, microbiological and parasitological analyzes of water for human consumption in a quilombola community of Santa Luzia do Norte in Alagoas. A cross-sectional, experimental and quantitative study was carried out between January and December 2019. The physical-chemical parameters of residual chlorine, turbidity, fluoride, fluoridation, color and pH were analyzed, microbiological analyses were based on the research of total and thermotolerant coliforms (E. coli) and parasitological analyses were performed based on the research of protozoa and intestinal helminths. Some physical-chemical parameters (turbidity and pH) were observed outside the limits required by the Ministry of Health, and the presence of total coliforms in some of the analyzed samples (17.85%), characterizing this community at risk related to waterborne diseases. The samples analyzed did not present infecting forms of parasitic species. Regarding the variables evaluated, the results found showed that the lack of adequate basic sanitation affects the quality of water used for human consumption by the quilombola population of Santa Luzia do Norte-AL.

https://doi.org/10.1590/1519-6984.260905

10.

Hepatic changes in Gallus gallus domesticus in Brazil
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Lopes, Marcelo C.

; Freitas Neto, Oliveiro C.

; Amaral, Camila I.

; Lacerda, Maira S.C.

; Fonseca, Clarissa S.

; Martins, Nelson R.S.

; Ecco, Roselene

Pesquisa Veterinária Brasileira

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2022, Volume 42 elocation e07078

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO: A ocorrência e a frequência de alterações hepáticas em aves, incluindo frangos de corte (FC), galinhas poedeiras (GP) e aves de subsistência (AS) foram investigadas. O estudo retrospectivo e prospectivo (2006-2021) foi realizado com um total de 300 casos de alterações hepáticas. Aves industriais (FC e GP) foram frequentemente acometidas (88%) e as alterações não infecciosas foram as mais comumente diagnosticadas (69%). Quanto à etiologia ou condição, as alterações hepáticas foram classificadas da seguinte forma: alterações degenerativas (42%), bacterianas (28%), metabólicas (15%), tóxicas (8%), virais (3%), neoplásicas (2%), bem como doenças por protozoários (1,5%) e distúrbios circulatórios (0,5%). Em relação ao tipo de ave, alterações degenerativas, tóxicas e hepatites virais foram mais frequentes nos FC. Distúrbios circulatórios e metabólicos, assim como hepatites bacterianas, foram diagnosticados com maior frequência nas GP. Neoplasias e hepatite por protozoário ocorreram com maior frequência em AS. O exame macroscópico associado à histopatologia possibilitou o diagnóstico da alteração hepática em 59% dos casos. Considerando a hepatite bacteriana em aves comerciais, o diagnóstico etiológico é de grande importância, em vista do risco para a saúde pública, apesar da óbvia importância devido às perdas de produtividade e condenação no processamento.

ABSTRACT: The occurrence and the frequency of hepatic changes in chickens, including broiler (BC), layer (LC) and backyard chickens (BYC) were investigated. The retrospective and prospective study (2006-2021) was conducted with a total of 300 cases of liver disorders. Industrial poultry (BC and LC) were frequently affected (88%) and noninfectious changes were the most diagnosed (69%). Considering etiology or conditions, the hepatic changes were classified as follows: degenerative changes (42%), bacterial (28%), metabolic (15%), toxic (8%), viral (3%), neoplastic (2%), protozoal diseases (1.5%) and circulatory disorders (0.5%). Regarding the type of bird, degenerative, toxic changes and viral hepatitis were more frequent in BC. Circulatory and metabolic disorders, as well as bacterial hepatitis, were more frequently diagnosed in LC. Neoplastic and protozoal hepatitis occurred more frequently in BYC. The macroscopic examination in association with histopathology enabled the diagnosis of the hepatic changes in 59% of the cases. Considering bacterial hepatitis in commercial poultry, the etiological diagnosis is highly important, in view of the risk for public health, despite the obvious importance due to the productivity losses and condemnation at processing.

https://doi.org/10.1590/1678-5150-pvb-7078

11.

Correlations between Web Searches and COVID-19 Epidemiological Indicators in Brazil
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Locatelli, Marcelo Sartori

; Cunha, Evandro L. T. P

; Guiginski, Janaína

; Franco, Ramon A. S

; Bernardes, Tereza

; Alzamora, Pedro Loures

; Silva, Daniel Victor F. da

; Ganem, Marcelo Augusto S

; Santos, Thiago H. M

; Carvalho, Anne I. R

; Souza, Leandro M. V

; Paixão, Gabriela P. F

; Chaves, Elisa França

; Santos, Guilherme Bezerra dos

; Santos, Rafael Vinícius dos

; Freitas, Amanda Cupertino de

; Flores, Matheus G

; Biezuner, Rachel F

; Cardoso, Rodolfo Lins

; Fonseca, Rodrigo Machado

; Silva, Ana Paula Couto da

; Meira Jr, Wagner

Brazilian Archives of Biology and Technology

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2022, Volume 65 elocation e22210648

Resumo: En | Texto: En | PDF: En

Abstract: COVID-19 rapidly spread across the world in an unprecedented outbreak with a massive number of infected and fatalities. The pandemic was heavily discussed and searched on the internet, which generated big amounts of data related to it. This led to the possibility of attempting to forecast coronavirus indicators using the internet data. For this study, Google Trends statistics for 124 selected search terms related to pandemic were used in an attempt to find which keywords had the best Spearman correlations with a lag, as well as a forecasting model. It was found that keywords related to coronavirus testing among some others, such as “I have contracted covid”, had high correlations (≥0.7) with few weeks of lag (≤4 weeks). Besides that, the ARIMAX model using those keywords had promising results in predicting the increase or decrease of epidemiological indicators, although it was not able to predict their exact values. Thus, we found that Google Trends data may be useful for predicting outbreaks of coronavirus a few weeks before they happen, and may be used as an auxiliary tool in monitoring and forecasting the disease in Brazil.

https://doi.org/10.1590/1678-4324-2022210648

12.

Diversity matters: opportunities in the study of the genetics of psychotic disorders in low- and middle-income countries in Latin America
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Fonseca, Lais

; Sena, Brena F.

; Crossley, Nicolas

; Lopez-Jaramillo, Carlos

; Koenen, Karestan

; Freimer, Nelson B.

; Bressan, Rodrigo A.

; Belangero, Sintia I.

; Santoro, Marcos L.

; Gadelha, Ary

Brazilian Journal of Psychiatry

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Dez 2021, Volume 43 Nº 6 Páginas 631 - 637

Resumo: En | Texto: En | PDF: En

Lack of diversity regarding genetic and environmental backgrounds weakens the generalization and clinical applicability of research findings on psychotic disorders. Notably, Latin Americans have been generally neglected in genetic studies, comprising less than 2% of genome-wide association study samples. But Latin American populations represent a unique opportunity for research, given the exceptionally high ethnic admixture of this group. Increasing genetic diversity is essential to improve the fine mapping of known regions associated with psychotic disorders, discover novel genetic associations, and replicate studies. Additionally, Latin America is characterized by massive social, political, and economic inequalities, all known risk factors for mental health issues, including psychotic disorders. This article aims to 1) discuss the challenges and advantages of studying Latin America’s particular genetic makeup and environmental context; 2) review previous studies conducted in the region; and 3) describe three Latin American research initiatives in progress: the Neuropsychiatric Genetics of Psychosis in Mexican Populations (NeuroMEX), the Paisa, and the Latin American Network for the Study of Early Psychosis (ANDES) studies.

https://doi.org/10.1590/1516-4446-2020-1240

13.

Adsorption of textile dye and textile effluent using organoclay from Northeast of Brazil
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Cavalcanti, J. V. F. L.

; Fonseca, C. C. da

; Silva, G. M. da

; Santiago, I. T.

; Tenório, L. L.

; Motta Sobrinho, M. A. da

; Baraúna, O. S.

Cerâmica

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Set 2021, Volume 67 Nº 383 Páginas 277 - 283

Resumo: En | Texto: En | PDF: En

Abstract The main goal of this research was to study the adsorptive capacity of an organophilic clay for the removal of textile dye Nylosan blue B113 and its further application in real textile effluent (RTE) treatment. The used clay known as Bofe was originated in the township of Boa Vista, State of Paraíba, Northeast of Brazil. Initially, the material was dried and powdered. Subsequently, the organophilic clay was synthesized by insertion of hexadecyltrimethylammonium bromide. Furthermore, the clay was characterized using the following analyses: cation exchange capacity (CEC), X-ray diffractometry (XRD), surface area analysis, and pH of point of zero charge (pHpzc). Then, batch adsorption systems were performed along with equilibrium/kinetic/thermodynamic studies. At last, keeping the same weight/volume ratio, a solution of real textile effluent was treated. Results showed CEC of 54.40 mmol/100g, lamellar expansion from 1.69 to 2.01 nm, maximum adsorptive capacity of 50 mg.g-1, and chemical oxygen demand (COD) removal of 74% (RTE).

https://doi.org/10.1590/0366-69132021673833094 68 downloads

14.

American Tegumentary Leishmaniasis in an endemic municipality in the North of Minas Gerais State: spatial analysis and socio-environmental factors
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Ursine, Renata Luiz

; Rocha, Marília Fonseca

; Sousa, Joel Fontes de

; Santos, Ronaldo Cardoso dos

; Soares, Marcelo Dias

; Gusmão, Maria Suely Fernandes

; Leite, Marcos Esdras

; Vieira, Thallyta Maria

Revista do Instituto de Medicina Tropical de São Paulo

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2021, Volume 63 elocation e2

Resumo: En | Texto: En | PDF: En

ABSTRACT American Tegumentary Leishmaniasis (ATL) is endemic in the municipality of Montes Claros, Minas Gerais State. The use of geotechnology such as spatial statistics and remote sensing has contributed to a better understanding of the eco-epidemiology of diseases, and consequently a better definition of control strategies. This study aimed to analyze the spatial distribution of probable sites of cases of ATL infection (2007-2011) in the municipality of Montes Claros and to identify related socio-environmental factors. Data on ATL cases notification were obtained from the Municipal Health Department of Montes Claros. The annual incidence of ATL in the municipality was calculated and the probable sites of infection were georeferenced. Crude Rate and the Local Empirical Bayesian Rate were calculated with census sectors considered as the unit of analysis. The Normalized Difference Vegetation Index (NDVI) was calculated from LANDSAT 5 TM images. The spatial association between the crude rate of ATL and the NDVI of the census tracts was evaluated using the Local Bivariate of Moran I. The socio-environmental aspects of household structures were assessed based on a structured questionnaire. The incidence of ATL in the evaluated period ranged from 6.2 to 16.6 cases/100,000 inhabitants. The highest rates of ATL occurrence were found in the census sectors located in the rural area and in the peripheral census sectors in the city. Through the Empirical Bayes Smoothed Rate map, it was found that in the peripheral areas of the city, the rates of ATL occurrence were lower than in the rural area and their values decreased as they approach the city center. Local Bivariate of Moran I showed a positive correlation between NDVI and crude ATL rates, with significant high-high clusters observed in the rural area and in the census sectors in the Western peripheral area of the city that have experienced an urban expansion concomitant to the period investigated. In most homes of people affected by the disease, there were domestic animals and organic matter in the peridomicile. In addition, a high percentage of individuals affected by ATL reported the presence of rodents circulating near their homes. In conclusion, it is possible that the disorderly expansion process in the city of Montes Claros favored the establishment of the ATL periurban and urban transmission cycle. These regions deserve special attention from health surveillance to combat this zoonosis.

https://doi.org/10.1590/s1678-9946202163002 898 downloads

15.

Poor Sleep quality and health-related quality of life impact in adolescents with and without chronic immunosuppressive conditions during COVID-19 quarantine
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Helito, Alberto C.

; Lindoso, Livia

; Sieczkowska, Sofia M.

; Astley, Camilla

; Queiroz, Ligia B.

; Rose, Natalia

; Santos, Claudia Renata P.

; Bolzan, Thalis

; Peralta, Rita María I.A.

; Franco, Ruth R.

; Cominato, Louise

; Pereira, Rosa Maria R.

; Tannuri, Uenis

; Campos, Lucia Maria A.

; Lourenço, Benito

; Toma, Ricardo K.

; Medeiros, Karina

; Watanabe, Andréia

; Grangeiro, Patricia Moreno

; Farhat, Sylvia C.

; Casella, Caio B.

; Polanczyk, Guilherme V.

; Gualano, Bruno

; Silva, Clovis A.

; Sallum, Adriana M. E.

; Iraha, Amanda Y.

; Ihara, Bianca P.

; Mazzolani, Bruna C.

; Martinez, Claudia A.

; Strabelli, Claudia A. A.

; Fonseca, Claudia B.

; Lima, Dandara C. C.

; Setoue, Debora N. D.

; Roz, Deborah F. P.

; Smaira, Fabiana I.

; Roschel, Hamilton

; Miyatani, Helena T.

; Marques, Isabela G.

; Oba, Jane

; Ferreira, Juliana C. O.

; Simon, Juliana R.

; Kozu, Katia

; Saccani, Ligia P.

; Martiniano, Lorena V. M.

; Miranda, Luana C. A.

; Silva, Luiz E. V.

; Laurentino, Moisés F.

; Aikawa, Nadia E.

; Sakita, Neusa K.

; Tanigava, Nicolas Y.

; Pereira, Paulo R. A.

; Palmeira, Patrícia

; Angelo, Simone S.

; Lavorato, Sofia S. M.

; Bernardes, Tamires M.

; Franco, Tathiane C.

; Viana, Vivianne S. L.

; Barros, Vera P. M. F. R.

; Zheng, Yingying

Clinics

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2021, Volume 76 elocation e3501

Resumo: En | Texto: En | PDF: En

OBJECTIVE: To assess the possible factors that influence sleep quality in adolescents with and without chronic immunosuppressive conditions quarantined during the coronavirus disease 2019 (COVID-19) pandemic. METHODS: This cross-sectional study included 305 adolescents with chronic immunocompromised conditions and 82 healthy adolescents. Online surveys were completed, which included questions on socio-demographic data and self-rated healthcare routine during COVID-19 quarantine and the following validated questionnaires: the Pittsburgh Sleep Quality Index (PSQI), Pediatric Quality of Life Inventory 4.0 (PedsQL4.0), and Pediatric Outcome Data Collection Instrument (PODCI). RESULTS: The median current age [14 (10-18) vs. 15 (10-18) years, p=0.847] and frequency of female sex (62% vs. 58%, p=0.571) were similar in adolescents with chronic conditions compared with healthy adolescents. The frequency of poor sleep quality was similar in both groups (38% vs. 48%, p=0.118). Logistic regression analysis, including both healthy adolescents and adolescents with chronic conditions (n=387), demonstrated that self-reported increase in screen time (odds ratio [OR] 3.0; 95% confidence interval [CI] 1.3-6.8; p=0.008) and intrafamilial violence report (OR 2.1; 95% CI 1.2-3.5; p=0.008) were independently associated with poor sleep quality in these adolescents. However, the PODCI global function score was associated with a lower OR for poor sleep quality (OR 0.97; 95% CI 0.94-0.99; p=0.001). Further logistic regression, including only adolescents with chronic conditions (n=305), demonstrated that self-reported increase in screen time (OR 3.1; 95% CI 1.4-6.8; p=0.006) and intrafamilial violence report (OR 2.0; 95% CI 1.2-3.4; p=0.011) remained independently associated with poor quality of sleep, whereas a lower PODCI global function score was associated with a lower OR for sleep quality (OR 0.96; 95% CI 0.94-0.98; p<0.001). CONCLUSION: Self-reported increases in screen time and intrafamilial violence report impacted sleep quality in both healthy adolescents and those with chronic conditions. Decreased health-related quality of life was observed in adolescents with poor sleep quality.

https://doi.org/10.6061/clinics/2021/e3501

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