Pesquisa | SciELO

Abstract Introduction Patients with psoriatic arthritis have some lipid metabolism changes and higher risk of metabolic syndrome (MetS) and cardiovascular diseases, regardless of traditional risk factors, suggesting that chronic inflammation itself plays a central role concerning the atherosclerosis. However, there is a lack of information regarding atherogenic pattern and lipoprotein subfractions burden in these individuals. Aim To evaluate the HDL and LDL-cholesterol plasmatic levels and their subfractions after a nutritional intervention in patients with psoriatic arthritis (PsA). Methods This was a randomized, placebo-controlled clinical trial of a 12-week nutritional intervention. PsA patients were randomly assigned to 1-Placebo: 1 g of soybean oil daily, no dietetic intervention; 2-Diet + Supplementation: an individualized diet, supplemented with 604 mg of omega-3 fatty acids, three times a day; and 3-Diet + Placebo: individualized diet + 1 g of soybean oil. The LDL subfractions were classified as non-atherogenic (NAth), atherogenic (Ath) or highly atherogenic (HAth), whereas the HDL subfractions were classified as small, medium, or large particles, according to the current recommendation based on lipoproteins electrophoresis. Results A total of 91 patients were included in the study. About 62% of patients (n = 56) had an Ath or HAth profile and the main risk factors associated were male gender, longer skin disease duration and higher BMI. Thirty-two patients (35%) had a high-risk lipoprotein profile despite having LDL plasmatic levels below 100 mg/dL. The 12-week nutritional intervention did not alter the LDL subfractions. However, there were significant improvement of HDL subfractions. Conclusion Recognizing the pro-atherogenic subfractions LDL pattern could be a relevant strategy for identifying PsA patients with higher cardiovascular risk, regardless total LDL plasmatic levels and disease activity. In addition, a short-term nutritional intervention based on supervised and individualized diet added to omega-3 fatty acids changed positively the HDLLARGE subfractions, while LDLLARGE subfraction was improved in hypercholesterolemic individuals. ClinicalTrials.gov identifier: NCT03142503 (http://www.clinicaltrials.gov/). MetS (MetS diseases atherosclerosis However individuals LDLcholesterol cholesterol PsA. . (PsA) randomized placebocontrolled placebo controlled 12week week 12 1Placebo Placebo 1-Placebo daily 2Diet Diet 2 Supplementation 60 omega3 omega 3 omega- day 3Diet nonatherogenic non NAth, NAth , (NAth) (Ath HAth, (HAth) small medium particles electrophoresis 9 study 62 n 56 gender BMI Thirtytwo Thirty two 35% 35 (35% highrisk high 10 mgdL dL mg/dL proatherogenic pro activity addition shortterm short term ClinicalTrialsgov ClinicalTrials gov identifier NCT NCT0314250 http//www.clinicaltrials.gov/. httpwwwclinicaltrialsgov http //www.clinicaltrials.gov/ www clinicaltrials (http://www.clinicaltrials.gov/) (PsA 6 (NAth (HAth 5 (35 NCT031425 http//www.clinicaltrials.gov/ wwwclinicaltrialsgov //www.clinicaltrials.gov (http://www.clinicaltrials.gov/ (3 NCT03142 http//www.clinicaltrials.gov (http://www.clinicaltrials.gov ( NCT0314 NCT031 NCT03 NCT0

https://doi.org/10.1186/s42358-024-00389-5

Cardiopulmonary radiographic changes in dogs naturally infected with Dirofilaria immitis
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Ferreira, Alexandre M.

; Netto, Carlos Eduardo C.

; Santos-Sousa, Carlos Augusto

; Souza Júnior, Paulo

; Bagetti Filho, Hélio José S.

; Abidu-Figueiredo, Marcelo

Pesquisa Veterinária Brasileira

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2024, Volume 44 elocation e07466

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

ABSTRACT: Heartworm disease is a zoonosis caused by Dirofilaria immitis, a nematode parasite of worldwide distribution and considered one of the most virulent of dogs, which are definitive and infected hosts during the blood meal of vector mosquitoes (Aedes sp., Anopheles sp. and Culex sp.). The disease has a worldwide prevalence, with a higher incidence in tropical and subtropical climate areas, and affects animals of any breed, sex, and age group. Most animals are asymptomatic, but the disease can cause various cardiovascular and respiratory symptoms. The pathophysiology is related to vessel obstruction and an intense inflammatory reaction in the lung parenchyma, with cardiovascular and respiratory symptoms leading to signs that can be severe and lead to the death of the host. It can be diagnosed through blood tests, and chest X-rays are used to assess the severity of clinical signs and help establish a prognosis. Cardiovascular alterations appear as an increase in vascular caliber, an increase in the right heart silhouette, and pulmonary patterns compatible with infection. This study aimed to describe the conditional radiographic changes caused by the parasite in the lungs, intrathoracic vessels and heart in 30 dogs, independent of breed and sex, with an average age of 9.9 years and an average weight of 10.25kg, originating from routine care at a veterinary hospital in the city of Rio de Janeiro, from January 2022 to December 2022. All animals were diagnosed with a positive heartworm infection and cardiorespiratory symptoms as essential conditions for participation in the study. The animals were x-rayed and had their lung patterns evaluated, in addition to measuring their vascular caliber and cardiac indices using vertebral-heart size (VHS), manubrium-heart size (MHS) and sphericity index (CSI). Most animals presented pulmonary patterns such as bronchoalveolar and bronchial and increased VHS and MHS indices. Increased and borderline values of CSI measurements were found in half of the patients, demonstrating that the parasite can trigger significant radiographic changes or present potential further worsening. ABSTRACT immitis dogs Aedes sp sp.. . sp.) prevalence areas sex group asymptomatic parenchyma host tests Xrays X rays prognosis silhouette lungs 3 99 9 9. 1025kg kg 10 25kg 10.25kg Janeiro 202 xrayed x rayed evaluated vertebralheart vertebral VHS, , (VHS) manubriumheart manubrium (MHS CSI. (CSI) patients worsening 1 20 (VHS (CSI 2

RESUMO: A dirofilariose é uma zoonose causada pela Dirofilaria immitis, parasita nematoide de distribuição mundial e considerado um dos mais patogênicos de cães, que são hospedeiros definitivos e infectados durante o repasto sanguíneo de mosquitos vetores (Aedes sp., Anopheles sp. e Culex sp.). A doença apresenta prevalência mundial, com maior incidência em áreas de clima tropical e subtropical, acometendo animais de qualquer raça, sexo e faixa etária. A maioria dos animais é assintomática, entretanto, a doença pode causar diversos sintomas cardiovasculares e respiratórios. A fisiopatologia se relaciona com a obstrução de vasos e com intensa reação inflamatória no tecido pulmonar, com sintomatologia cardiovascular e respiratória, levando a sinais que podem ser graves e levar ao óbito do hospedeiro. Pode ser diagnosticada através de exames de sangue e as radiografias de tórax são utilizadas para avaliar a gravidade dos sinais clínicos e auxiliar no estabelecimento do prognóstico. Alterações cardiovasculares surgem como aumento de calibre vascular, aumento de silhueta cardíaca direita e padrões pulmonares compatíveis com infecção. No presente artigo objetivou-se descrever as alterações radiográficas estabelecidas pelo parasita nos pulmões, nos vasos intratorácicos e no coração em 30 cães, independente de raça e sexo, com média de idade 9,9 anos e média de peso 10,25kg, oriundos da rotina de atendimento de um hospital veterinário na cidade do Rio de Janeiro, entre Janeiro de 2022 e Dezembro de 2022. Todos os animais possuem diagnóstico positivo para infecção por dirofilariose e sintomatologia cardiorrespiratória como condição indispensável para pertencerem ao estudo. Os animais foram radiografados e tiveram os padrões pulmonares avaliados, além da medição do calibre vascular e dos índices cardíacos através do VHS (índice cardio-vertebral), MHS (ou índice manúbrio-esternal) e CSI (índice de esfericidade). A maioria dos animais apresentou padrão pulmonar como broncoalveolar e bronquial e índices de VHS e MHS aumentados. Aumento e valores limítrofes das medidas de CSI foram encontrados em metade dos pacientes, demonstrando que o parasita pode desencadear alterações radiográficas significativas ou apresentar potencial agravamento posterior. RESUMO immitis cães Aedes sp sp.. . sp.) subtropical etária assintomática entretanto respiratórios respiratória hospedeiro prognóstico objetivouse objetivou pulmões 3 99 9 9, 1025kg kg 10 25kg 10,25kg 202 estudo avaliados cardiovertebral, cardiovertebral cardio vertebral , cardio-vertebral) manúbrioesternal manúbrio esternal manúbrio-esternal esfericidade. esfericidade esfericidade) aumentados pacientes posterior 1 20 cardio-vertebral 2

https://doi.org/10.1590/1678-5150-pvb-7466

Does the use of panoramic radiography add information in the temporomandibular joint evaluation in Juvenile Idiopathic Arthritis patients? A case control study patients
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Rosa, Vera Lucia Mestre

; Zwir, Liete M. Figueiredo

; Dutra, Marcelo Eduardo Pereira

; Russo, Gleice Clemente Souza

; Rodrigues, Wellington Douglas R.

; Terreri, Maria Teresa

Advances in Rheumatology

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2023, Volume 63 elocation 6

Resumo: En | Texto: En | PDF: En

Abstract Objective To determine the frequency of radiographic changes in the temporomandibular joint, in a representative population of patients with Juvenile Idiopathic Arthritis (JIA) and to compare with findings in healthy controls matched by sex and age. Patients and Methods One hundred and thirty-seven panoramic radiographies (PR) from JIA patients of a pediatric rheumatology outpatient clinic were prospectively evaluated and compared to 137 PR from healthy individuals. Results 102 (74.5%) JIA patients and 47 (34.3%) controls showed at least one radiological alteration (p < 0.001). The following radiographic alterations were more frequently observed in JIA patients than in controls: erosion (p < 0.001), altered condylar morphology (p < 0.001), disproportion between condylar process and the coronoid process (p < 0.001) and accentuated curve in the antegonial notch (p = 0.002). Twenty patients (14.6%) presented the four radiographic alterations simultaneously compared to only two controls (1.5%) (p < 0.001). Conclusion Due to the difference in the frequency of findings in the PR of patients and controls, we concluded that PR has value as a screening tool. In the presence of major changes in the mandible head in the PR of patients with a confirmed diagnosis of JIA, MRI should be considered to detect an active inflammatory process in this joint. joint (JIA age thirtyseven thirty seven (PR 13 individuals 10 74.5% 745 74 5 (74.5% 4 34.3% 343 34 3 (34.3% p 0.001. 0001 0.001 . 0 001 0.001, , 0.002. 0002 0.002 002 0.002) 14.6% 146 14 6 (14.6% 1.5% 15 1 (1.5% tool 74.5 7 (74.5 34.3 (34.3 000 0.00 00 14.6 (14.6 1.5 (1.5 74. (74. 34. (34. 0.0 14. (14. 1. (1. (74 (34 0. (14 (1 (7 (3 (

https://doi.org/10.1186/s42358-023-00285-4

Multidisciplinary Scientific Cruises for Environmental Characterization in the Santos Basin – Methods and Sampling Design
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Moreira, Daniel L.

; Dalto, Adriana G.

; Figueiredo JR, Alberto G.

; Valerio, Aline M.

; Detoni, Amalia M. S.

; Bonecker, Ana C. T.

; Signori, Camila N.

; Namiki, Cláudia

; Sasaki, Dalton K.

; Pupo, Daniel V.

; Silva, Danilo A.

; Kutner, Deborah S.

; Duque-Castaño, Diana C.

; Marcon, Eduardo H.

; Gallotta, Fabiana D. C.

; Paula, Fabiana S.

; Gallucci, Fabiane

; Roque, Gabriela C. F.

; Campos, Giulia S.

; Fonseca, Gustavo

; Mattos, Gustavo

; Lavrado, Helena P.

; Silveira, Ilson C. A. da

; Costa, Jessica O.

; Santos Filho, João R. dos

; Carneiro, Juliane C.

; Moreira, Julio C.F.

; Rozo, Laura

; Araujo, Leandro F.M.

; Lazzari, Letícia

; Silva, Letícia O. da

; Michelazzo, Luan S.

; Fernandes, Luciano F.

; Dottori, Marcelo

; Araújo Jr., Marcus A. G. de

; Chuqui, Mateus G.

; Ceccopieri, Milena

; Borges-Silva, Milton

; Kampel, Milton

; Bergo, Natascha M.

; Silva, Paulo V. M.

; Tura, Pedro M.

; Moura, Rafael B. de

; Romano, Renato G.

; Martins, Renato P.

; Carreira, Renato S.

; Toledo, Rodrigo G.A.

; Bonecker, Sérgio L.C.

; Disaró, Sibelle T.

; Rodrigues, Silvana V.

; Corbisier, Thais N.

; Vicente, Thaisa M.

; Paiva, Vitor G. de

; Pellizari, Vivian H.

; Belo, Wellington C.

; Brandini, Frederico P.

; Sousa, Silvia H.M

Ocean and Coastal Research

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2023, Volume 71 Supl. 3 elocation e23022

Resumo: En | Texto: En | PDF: En

Abstract The Santos Basin (SB) is the main petroliferous basin in the Brazilian continental margin and one of the most studied marine areas in Brazil. However, historical data suggest that new efforts should be carried out to acquire quantitative biological data, especially in the deep sea, to establish the baseline of essential ocean variables in different ecosystems for future monitoring programs. The Brazilian energy company Petrobras planned and executed 24 oceanographic cruises over a period of 2 years to assess the benthic (SANSED cruise) and pelagic (SANAGU cruise) systems of the SB (356 days at sea in 2019 and 2021/2022). These efforts were part of the Santos Project, which comprised a comprehensive environmental study aimed at investigating benthic and pelagic variables to characterize ecology, biogeochemistry, thermohaline properties of water masses, and ocean circulation patterns, geomorphology, and sedimentology, as well as organic and inorganic chemistry. Here we present the detailed sampling designs and the field methods employed on board, during the SB scientific cruises. All sampling protocols were based on standardized approaches. For the benthos analyses, triplicate sediment samples were performed using a GOMEX-type box corer (0.25 m²) or a large modified Van Veen grab (0.75 m²) at 100 stations ranging from 25 to 2400 m depth. At each station, 25 geochemical and physico-chemical parameters were analyzed in addition to micro-, meio-, and macrofauna and living foraminifera samples. For the pelagic system, 60 stations were selected to investigate the plankton community, ranging in size from pico- to macroplankton, through vertical, horizontal, and oblique net hauls (20, 200, and 500 μm mesh size), as well as 25 biogeochemical parameters collected with an aid of a CTD-rosette sampler. Part of this scientific information also serves the Regional Environmental Characterization Project (PCR-BS) in support of Petrobras’ Santos Basin drilling licensing process led by the Brazilian Environmental Agency – IBAMA. This project contributes to the sustainable development of the SB, in line with the guidelines of the United Nations Decade of Ocean Science for Sustainable Development. (SB Brazil However programs SANSED cruise SANAGU 356 (35 201 2021/2022. 20212022 2021/2022 . 2021 2022 2021/2022) ecology biogeochemistry masses patterns geomorphology sedimentology chemistry board approaches analyses GOMEXtype GOMEX type 0.25 025 0 (0.2 m² 0.75 075 75 (0.7 10 240 depth station physicochemical physico chemical micro, micro , micro- meio, meio meio- system 6 community pico macroplankton vertical horizontal 20, 20 (20 200 50 size, size) CTDrosette CTD rosette sampler PCRBS PCR BS (PCR-BS IBAMA Development 35 (3 2021202 2021/202 202 0.2 02 (0. 0.7 07 7 1 (2 5 3 ( 202120 2021/20 0. (0 20212 2021/2 2021/

https://doi.org/10.1590/2675-2824071.22072dlm

First record of insect-plant interaction in Late Cretaceous fossils from Nelson Island (South Shetland Islands Archipelago), Antarctica insectplant insect plant South Archipelago, Archipelago , Archipelago)
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SANTOS FILHO, EDILSON B. DOS

; BRUM, ARTHUR S.

; SOUZA, GEOVANE A. DE

; FIGUEIREDO, RODRIGO G.

; USMA, CRISTIAN D.

; RICETTI, JOÃO HENRIQUE Z.

; TREVISAN, CRISTINE

; LEPPE, MARCELO

; SAYÃO, JULIANA M.

; LIMA, FLAVIANA J.

; OLIVEIRA, GUSTAVO R.

; KELLNER, ALEXANDER W.A.

Anais da Academia Brasileira de Ciências

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2023, Volume 95 Supl. 3 elocation e20231268

Resumo: En | Texto: En | PDF: En

Abstract Despite the enormous paleobotanical record on different islands of the Antarctic Peninsula, the evidence of insect activity associated with fossilized plants is scarce. Here we report the first evidence of insect-plant interaction from Cretaceous deposits, more precisely from a new locality at the Rip Point area, Nelson Island (Antarctic Peninsula). The macrofossil assemblage includes isolated Nothofagus sp. leaf impressions, a common component of the Antarctic paleoflora. Two hundred leaves were examined, of which 15 showed evidence of insect activity, displaying variations in size, shape, and preservation. Two types of interaction damage, galls and mines, were identified. A single specimen retained a circular scar recognized as galling scar, while meandering tracks were considered mines. These traces of herbivore insect activity, correspond to the oldest known record of this type of interaction of West Antarctica and the oldest record of insect-plant interaction in Nothofagus sp. reported so far. Peninsula scarce insectplant plant deposits area Peninsula. . Peninsula) sp impressions paleoflora examined 1 size shape preservation damage mines identified far

https://doi.org/10.1590/0001-3765202320231268

Práticas de ressuscitação volêmica em unidades de terapia intensiva brasileiras: uma análise secundária do estudo Fluid-TRIPS
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Freitas, Flavio Geraldo Rezende de

; Hammond, Naomi

; Li, Yang

; Azevedo, Luciano Cesar Pontes de

; Cavalcanti, Alexandre Biasi

; Taniguchi, Leandro

; Gobatto, André

; Japiassú, André Miguel

; Bafi, Antonio Tonete

; Mazza, Bruno Franco

; Noritomi, Danilo Teixeira

; Dal-Pizzol, Felipe

; Bozza, Fernando

; Salluh, Jorge Ibrahin Figueira

; Westphal, Glauco Adrieno

; Soares, Márcio

; Assunção, Murillo Santucci César de

; Lisboa, Thiago

; Lobo, Suzana Margarete Ajeje

; Barbosa, Achilles Rohlfs

; Ventura, Adriana Fonseca

; Souza, Ailson Faria de

; Silva, Alexandre Francisco

; Toledo, Alexandre

; Reis, Aline

; Cembranel, Allan

; Rea Neto, Alvaro

; Gut, Ana Lúcia

; Justo, Ana Patricia Pierre

; Santos, Ana Paula

; Albuquerque, André Campos D. de

; Scazufka, André

; Rodrigues, Antonio Babo

; Fernandino, Bruno Bonaccorsi

; Silva, Bruno Goncalves

; Vidal, Bruno Sarno

; Pinheiro, Bruno Valle

; Pinto, Bruno Vilela Costa

; Feijo, Carlos Augusto Ramos

; Abreu Filho, Carlos de

; Bosso, Carlos Eduardo da Costa Nunes

; Moreira, Carlos Eduardo Nassif

; Ramos, Carlos Henrique Ferreira

; Tavares, Carmen

; Arantes, Cidamaiá

; Grion, Cintia

; Mendes, Ciro Leite

; Kmohan, Claudio

; Piras, Claudio

; Castro, Cristine Pilati Pileggi

; Lins, Cyntia

; Beraldo, Daniel

; Fontes, Daniel

; Boni, Daniela

; Castiglioni, Débora

; Paisani, Denise de Moraes

; Pedroso, Durval Ferreira Fonseca

; Mattos, Ederson Roberto

; Brito Sobrinho, Edgar de

; Troncoso, Edgar M. V.

; Rodrigues Filho, Edison Moraes

; Nogueira, Eduardo Enrico Ferrari

; Ferreira, Eduardo Leme

; Pacheco, Eduardo Souza

; Jodar, Euzebio

; Ferreira, Evandro L. A.

; Araujo, Fabiana Fernandes de

; Trevisol, Fabiana Schuelter

; Amorim, Fábio Ferreira

; Giannini, Fabio Poianas

; Santos, Fabrício Primitivo Matos

; Buarque, Fátima

; Lima, Felipe Gallego

; Costa, Fernando Antonio Alvares da

; Sad, Fernando Cesar dos Anjos

; Aranha, Fernando G.

; Ganem, Fernando

; Callil, Flavio

; Costa Filho, Francisco Flávio

; Dall´Arto, Frederico Toledo Campo

; Moreno, Geovani

; Friedman, Gilberto

; Moralez, Giulliana Martines

; Silva, Guilherme Abdalla da

; Costa, Guilherme

; Cavalcanti, Guilherme Silva

; Betônico, Gustavo Navarro

; Reis, Hélder

; Araujo, Helia Beatriz N.

; Hortiz Júnior, Helio Anjos

; Guimaraes, Helio Penna

; Urbano, Hugo

; Maia, Israel

; Santiago Filho, Ivan Lopes

; Farhat Júnior, Jamil

; Alvarez, Janu Rangel

; Passos, Joel Tavares

; Paranhos, Jorge Eduardo da Rocha

; Marques, José Aurelio

; Moreira Filho, José Gonçalves

; Andrade, Jose Neto

; Sobrinho, José Onofre de C

; Bezerra, Jose Terceiro de Paiva

; Alves, Juliana Apolônio

; Ferreira, Juliana

; Gomes, Jussara

; Sato, Karina Midori

; Gerent, Karine

; Teixeira, Kathia Margarida Costa

; Conde, Katia Aparecida Pessoa

; Martins, Laércia Ferreira

; Figueirêdo, Lanese

; Rezegue, Leila

; Tcherniacovsk, Leonardo

; Ferraz, Leone Oliveira

; Cavalcante, Liane

; Rabelo, Ligia

; Miilher, Lilian

; Garcia, Lisiane

; Tannous, Luana

; Hajjar, Ludhmila Abrahão

; Paciência, Luís Eduardo Miranda

; Cruz Neto, Luiz Monteiro da

; Bley, Macia Valeria

; Sousa, Marcelo Ferreira

; Puga, Marcelo Lourencini

; Romano, Marcelo Luz Pereira

; Nobrega, Marciano

; Arbex, Marcio

; Rodrigues, Márcio Leite

; Guerreiro, Márcio Osório

; Rocha, Marcone

; Alves, Maria Angela Pangoni

; Rosa, Maria Doroti

; Dias, Mariza D’Agostino

; Martins, Miquéias

; Oliveira, Mirella de

; Moretti, Miriane Melo Silveira

; Matsui, Mirna

; Messender, Octavio

; Santarém, Orlando Luís de Andrade

; Silveira, Patricio Júnior Henrique da

; Vassallo, Paula Frizera

; Antoniazzi, Paulo

; Gottardo, Paulo César

; Correia, Paulo

; Ferreira, Paulo

; Torres, Paulo

; Silva, Pedro Gabrile M. de Barros e

; Foernges, Rafael

; Gomes, Rafael

; Moraes, Rafael

; Nonato filho, Raimundo

; Borba, Renato Luis

; Gomes, Renato V

; Cordioli, Ricardo

; Lima, Ricardo

; López, Ricardo Pérez

; Gargioni, Ricardo Rath de Oliveira

; Rosenblat, Richard

; Souza, Roberta Machado de

; Almeida, Roberto

; Narciso, Roberto Camargo

; Marco, Roberto

; waltrick, Roberto

; Biondi, Rodrigo

; Figueiredo, Rodrigo

; Dutra, Rodrigo Santana

; Batista, Roseane

; Felipe, Rouge

; Franco, Rubens Sergio da Silva

; Houly, Sandra

; Faria, Sara Socorro

; Pinto, Sergio Felix

; Luzzi, Sergio

; Sant’ana, Sergio

; Fernandes, Sergio Sonego

; Yamada, Sérgio

; Zajac, Sérgio

; Vaz, Sidiner Mesquita

; Bezerra, Silvia Aparecida Bezerra

; Farhat, Tatiana Bueno Tardivo

; Santos, Thiago Martins

; Smith, Tiago

; Silva, Ulysses V. A.

; Damasceno, Valnei Bento

; Nobre, Vandack

; Dantas, Vicente Cés de Souza

; Irineu, Vivian Menezes

; Bogado, Viviane

; Nedel, Wagner

; Campos Filho, Walther

; Dantas, Weidson

; Viana, William

; Oliveira Filho, Wilson de

; Delgadinho, Wilson Martins

; Finfer, Simon

; Machado, Flavia Ribeiro

Revista Brasileira de Terapia Intensiva

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Abr 2021, Volume 33 Nº 2 Páginas 206 - 218

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: Descrever as práticas de ressuscitação volêmica em unidades de terapia intensiva brasileiras e compará-las com as de outros países participantes do estudo Fluid-TRIPS. Métodos: Este foi um estudo observacional transversal, prospectivo e internacional, de uma amostra de conveniência de unidades de terapia intensiva de 27 países (inclusive o Brasil), com utilização da base de dados Fluid-TRIPS compilada em 2014. Descrevemos os padrões de ressuscitação volêmica utilizados no Brasil em comparação com os de outros países e identificamos os fatores associados com a escolha dos fluidos. Resultados: No dia do estudo, foram incluídos 3.214 pacientes do Brasil e 3.493 pacientes de outros países, dos quais, respectivamente, 16,1% e 26,8% (p < 0,001) receberam fluidos. A principal indicação para ressuscitação volêmica foi comprometimento da perfusão e/ou baixo débito cardíaco (Brasil 71,7% versus outros países 56,4%; p < 0,001). No Brasil, a percentagem de pacientes que receberam soluções cristaloides foi mais elevada (97,7% versus 76,8%; p < 0,001), e solução de cloreto de sódio a 0,9% foi o cristaloide mais comumente utilizado (62,5% versus 27,1%; p < 0,001). A análise multivariada sugeriu que os níveis de albumina se associaram com o uso tanto de cristaloides quanto de coloides, enquanto o tipo de prescritor dos fluidos se associou apenas com o uso de cristaloides. Conclusão: Nossos resultados sugerem que cristaloides são usados mais frequentemente do que coloides para ressuscitação no Brasil, e essa discrepância, em termos de frequências, é mais elevada do que em outros países. A solução de cloreto de sódio 0,9% foi o cristaloide mais frequentemente prescrito. Os níveis de albumina sérica e o tipo de prescritor de fluidos foram os fatores associados com a escolha de cristaloides ou coloides para a prescrição de fluidos.

Abstract Objective: To describe fluid resuscitation practices in Brazilian intensive care units and to compare them with those of other countries participating in the Fluid-TRIPS. Methods: This was a prospective, international, cross-sectional, observational study in a convenience sample of intensive care units in 27 countries (including Brazil) using the Fluid-TRIPS database compiled in 2014. We described the patterns of fluid resuscitation use in Brazil compared with those in other countries and identified the factors associated with fluid choice. Results: On the study day, 3,214 patients in Brazil and 3,493 patients in other countries were included, of whom 16.1% and 26.8% (p < 0.001) received fluids, respectively. The main indication for fluid resuscitation was impaired perfusion and/or low cardiac output (Brazil: 71.7% versus other countries: 56.4%, p < 0.001). In Brazil, the percentage of patients receiving crystalloid solutions was higher (97.7% versus 76.8%, p < 0.001), and 0.9% sodium chloride was the most commonly used crystalloid (62.5% versus 27.1%, p < 0.001). The multivariable analysis suggested that the albumin levels were associated with the use of both crystalloids and colloids, whereas the type of fluid prescriber was associated with crystalloid use only. Conclusion: Our results suggest that crystalloids are more frequently used than colloids for fluid resuscitation in Brazil, and this discrepancy in frequencies is higher than that in other countries. Sodium chloride (0.9%) was the crystalloid most commonly prescribed. Serum albumin levels and the type of fluid prescriber were the factors associated with the choice of crystalloids or colloids for fluid resuscitation.

https://doi.org/10.5935/0103-507x.20210028 273 downloads

Polyculture of bullfrog tadpoles and Nile tilapia fry
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SARTURI, CRISTIANE

; HELUY, GUILHERME M.

; SARMIENTO, PETER C.J.

; FIGUEIREDO, PAULO GUSTAVO

; JORGE, THIAGO B.F.

; MELLO, SILVIA CONCEIÇÃO R.P.

; RAMOS, LEONARDO R.V.

; PEREIRA, MARCELO M.

Anais da Academia Brasileira de Ciências

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2021, Volume 93 elocation e20210270

Resumo: En | Texto: En | PDF: En

Abstract Two experiments were carried out to test better stocking proportion according to animal size for tilapia (Oreochromis niloticus) and tadpole (Lithobates catesbeianus). The experiments were laid out in a completely randomized design with five treatments (in Experiment I) and four treatments (in Experiment II). In Experiment I, the treatments consisted of a tilapia monoculture; a 75% tilapia + 25% tadpole polyculture; a 50% tilapia + 50% tadpole; a 25% tilapia + 75% tadpole; and a tadpole monoculture. In Experiment II, the treatments were represented by a tilapia monoculture; a 12.5% tilapia + 87.5% tadpole polyculture; a 25% tilapia + 75% tadpole; and a tadpole monoculture. In the first trial, mortality rate differed significantly, with the polyculture treatments having almost 100% mortality of tadpoles. In the second experiment, after adjustments in the initial size of the species, there were significant differences between treatments, with the 12.5% tilapia + 87.5% tadpole polyculture and the tadpole monoculture providing the best results. Regardless of the chosen density, for a polyculture of Nile tilapia and bullfrog tadpoles, ideal conditions would be stocking tilapia fry weighing 50% of the weight initial tadpoles and the proportion of one tilapia for seven tadpoles.

https://doi.org/10.1590/0001-3765202120210270 14 downloads

Sampling Processes and Intensities for the Geostatistical Modeling of an Unevenly Aged Forest
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Roveda, Marcelo

; Figueiredo Filho, Afonso

; Pelissari, Allan

; Genú, Aline

Floresta e Ambiente

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2019, Volume 26 Nº 1 elocation e20160609

Resumo: En | Texto: En | PDF: En

ABSTRACT The aim of this study was to estimate the basal area, through traditional sampling processes and geostatistical interpolation, and compare it to the forest census carried out in 25 ha of a Mixed Ombrophilous Forest remnant. The sampling simulations were structured for the systematic sampling, two stages, and simple random, in intensities 5, 11, and 22% of the potential sample units of 25 × 25 m. The increase in sample intensity for the systematic sampling and two stages revealed a higher level of spatial behavior details of the basal area, whereas when comparing the census with sampling, it was observed that the geostatistical interpolation shows ability to improve the accuracy of the basal area estimation.

https://doi.org/10.1590/2179-8087.060916 665 downloads

6ª DIRETRIZES DE MONITORIZAÇÃO AMBULATORIAL DA PRESSÃO ARTERIAL E 4ª DIRETRIZES DE MONITORIZAÇÃO RESIDENCIAL DA PRESSÃO ARTERIAL
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Brandão, Andrea A.

; Alessi, Alexandre

; Feitosa, Audes Magalhães

; Machado, Carlos Alberto

; Figueiredo, Carlos Eduardo Poli de

; Amodeo, Celso

; Rodrigues, Cibele Isaac Saad

; Forjaz, Claudia Lucia de Moraes

; Giorgi, Dante Marcelo Artigas

; Mion Júnior, Décio

; Coelho, Eduardo Barbosa

; Nobre, Fernando

; Lima Júnior, Emilton

; Plavnik, Frida Liane

; Silva, Giovanio Vieira da

; Chaves Júnior, Hilton

; Barbosa, Eduardo Costa Duarte

; Vilela-Martin, José Fernando

; Ribeiro, José Marcio

; Gusmão, Josiane Lima de

; Toledo, Juan Carlos Yugar

; Bortolotto, Luiz Aparecido

; Scala, Luiz Cesar Nazário

; Gomes, Marco Antônio Mota

; Malachias, Marcus Vinícius Bolívar

; Neves, Mario Fritsch Toros

; Wajngarten, Mauricio

; Gus, Miguel

; Passarelli Júnior, Oswaldo

; Jardim, Paulo Cesar Brandão Veiga

; Miranda, Roberto Dischinger

; Paula, Rogério Baumgratz de

; Ferreira Filho, Sebastião Rodrigues

; Andrade, Solange

; Geleilete, Tufik J. M.

; Koch, Vera Hermina K.

; Souza, Weimar Kunz Sebba Barroso de

; Oigman, Wille

Arquivos Brasileiros de Cardiologia

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Mai 2018, Volume 110 Nº 5 Páginas 1 - 29

Resumo: Pt | Texto: Pt | PDF: Pt

https://doi.org/10.5935/abc.20180074 2708 downloads

10.

Effects of Different Numbers of Fungicide Application on the Proximate Composition of Soybean
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Michels, Roger N.

; Bonafe, Elton G.

; Figueiredo, Luana C.

; Suzuki, Rúbia M.

; Tonin, Lilian D.

; Montanher, Paula F.

; Martins, Alessandro Francisco

; Visentainer, Jesui V.

; Canteri, Marcelo G.

; Silva, Marcelo Augusto A.

Journal of the Brazilian Chemical Society

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Out 2016, Volume 27 Nº 10 Páginas 1727 - 1735

Resumo: En | Texto: En | PDF: En

This study aimed to evaluate the effect of strobilurin (pyraclostrobin) + triazole (epoxiconazole) fungicides application on the proximate composition of soybeans. Six treatments of varying numbers of fungicide applications following soybean germination, termed T1 (control), T2, T3, T4, T5, and T6, were assessed for this experiment. Based on the results, there were only minor differences in the proximate composition of soybeans in terms of moisture, ash, crude protein, and total lipid contents. In contrast, there were large effects on the contents of phenolic compounds and the levels of phytosterols and tocopherols, which varied greatly among the fungicide application treatments. Multivariate statistical analysis was applied to identify critical issues regarding the potential for the production of soybeans enriched in phenolic compounds, tocopherols, and essential fatty acids (α-linolenic and linoleic acids, representatives of the omega-3 and omega-6 families, respectively) associated with the number of sprayings applied during the development of soybean crops.

https://doi.org/10.5935/0103-5053.20160053 613 downloads

11.

Origem e principais ramificações das artérias mesentéricas cranial e caudal em avestruz (Struthio camelus Linnaeus, 1758)
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Neira, Ronaldo Hertel

; Estruc, Thais M.

; Nascimento, Renata M.

; Santos-Sousa, Carlos A.

; Souza-Junior, Paulo de

; Abidu-Figueiredo, Marcelo

Pesquisa Veterinária Brasileira

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Set 2016, Volume 36 Nº 9 Páginas 912 - 918

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo: As artérias mesentéricas das aves são importantes para a irrigação do aparelho digestório e encontram-se associadas ao ganho de peso e conversão alimentar. Objetivou-se descrever as origens, esqueletopias, medidas e principais ramificações das artérias mesentéricas cranial e caudal em avestruzes. Foram utilizados 41 cadáveres de filhotes de avestruzes, 23 machos e 18 fêmeas, obtidos de um criadouro após morte natural. Os cadáveres foram fixados com formaldeído a 10% e tiveram o sistema vascular preenchido com Petrolatex® S-65 colorido. As artérias mesentéricas, cranial e caudal e seus ramos proximais foram dissecados "in situ" e medidas com paquímetro digital. A artéria mesentérica cranial teve comprimento médio de 3,68 ± 1,04 cm e surgiu da aorta descendente ao nível da oitava vértebra torácica na maioria dos casos. Ramificou-se em artérias jejunal e ileocecal. A artéria jejunal ofereceu média de 14,04 ±2,08 ramos ao jejuno e a artéria ileocecal originou um ramo retal e outro que se bifurcou para derivar ramos para íleo, ceco e reto. Em um espécime macho a artéria ileocecal foi ramo da artéria celíaca. A artéria mesentérica caudal originou-se na porção terminal da aorta descendente predominantemente ao nível das 4ª e 6ª vértebras sacro-caudais. Perto da extremidade caudal do rim emitiu os ramos cranial e caudal. O primeiro irrigou o reto e anastomosou-se com ramo retal da artéria mesentérica cranial; o segundo irrigou a porção final do reto, cloaca e bolsa cloacal. Não houve diferença significativa (p<0,05) entre as medidas, esqueletopia e número de ramificações das artérias entre os sexos.

Abstract: The mesenteric arteries of birds are important for the irrigation of the digestive tract and are associated with weight gain and food conversion. This study aimed to describe the origins, skeletopy, measures and main branches of cranial and caudal mesenteric arteries in ostriches. Forty-one cadavers of ostrich chicks, 23 males and 18 females, obtained from a farmer after natural death. The cadavers were fixed with 10% formaldehyde solution and their vascular system was filled with colored Petrolatex® S-65. The cranial and caudal mesenteric arteries and its proximal branches were dissected in situ and measured with a digital caliper. The mesenteric artery had an average length of 3.68cm±1.04 and emerged from the descending aorta at the level of the eighth thoracic vertebra in most cases; it branched into jejunal and ileocecal arteries. The jejunal artery sent a mean of 14 (14.04±2.08) branches to the jejunum. The ileocecal artery sent a rectal branch and another branch that irrigated ileum, cecum and rectum. In a male specimen the ileocecal artery was originated from the celiac artery. The caudal mesenteric artery emerged in the terminal portion of the descending aorta predominantly at the level of the 4th and 6th sacrocaudal vertebrae. Near the caudal end of the kidney it issued the cranial and caudal branches. The first irrigated the rectum and anastomosed with the rectal branch of the cranial mesenteric artery; the second irrigated the final part of the rectum, cloaca and cloacal bursa. There was no significant difference (p<0.05) between measurements, skeletopy and number of branches of the arteries between genders.

https://doi.org/10.1590/s0100-736x2016000900019 1596 downloads

12.

Facile Microwave-Assisted Synthesis of Lanthanide Doped CaTiO3 Nanocrystals
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Pereira, Sandra C.

; Figueiredo, Alberthmeiry T.

; Barrado, Cristiano M.

; Stoppa, Marcelo H.

; Dwivedi, Yashashchandra

; Li, Maximo S.

; Longo, Elson

Journal of the Brazilian Chemical Society

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Nov 2015, Volume 26 Nº 11 Páginas 2339 - 2345

Resumo: En | Texto: En | PDF: En

This article discusses a simple approach for the microwave-assisted synthesis of good quality nanosized calcium titanate crystals doped with trivalent Tm and Yb lanthanide ions. The prepared nanoparticles had a microcube-like structure and a crystallite size of ca. 47 nm. The structure of the nanocrystals was analyzed by X-ray diffraction (XRD) and scanning electron microscopy (SEM), and their spectroscopic behavior was examined at a laser excitation wavelength of 350.7 nm. It was found that doping CaTiO3 nanocrystals with Yb and Tm leads to about 250-fold brighter photoluminescence (PL) emissions in the blue and near-infrared regions than that emitted by pure CaTiO3 nanocrystals. The PL emission was correlated with the structural disorder.

https://doi.org/10.5935/0103-5053.20150229 81519 downloads

13.

Avaliação a médio prazo do controle de fatores de risco de doença cardiovascular em coorte prospectiva de pacientes de alto risco tratados por intervenção coronária percutânea
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Pavão, Rafael Brolio

; Marin-Neto, José Antonio

; Novaes, Gustavo Caires

; Pinto, Marcelo Rodrigues

; Figueiredo, Geraldo Luiz

; Lago, Igor Matos

; Lima Filho, Moysés de Oliveira

; Lemos, Daniel Conterno

; Tonani, Monique

; Antloga, Cleide Marques

; Oliveira, Luciana Correa de

; Marchini, Julio F. M.

Revista Brasileira de Cardiologia Invasiva

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Jun 2013, Volume 21 Nº 2 Páginas 121 - 127

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

INTRODUÇÃO: A prevenção secundária após intervenção coronária percutânea (ICP) é fundamental para melhorar a sobrevida livre de eventos e consiste principalmente no controle de fatores de risco. Analisou-se a prevenção secundária de pacientes de alto risco, incluídos prospectivamente no estudo Sequence Variation in Platelet Aggregation in Response to Clopidogrel and aspirin (SPARC). MÉTODOS: Foram arrolados 187 pacientes consecutivos entre dezembro de 2009 e fevereiro de 2011, tratados por ICP com stent e avaliados em retornos ambulatoriais de 30 dias, 3 meses, 6 meses e 12 meses quanto ao controle de hipertensão arterial, disglicemia, dislipidemia e tabagismo, e medidas terapêuticas respectivas. RESULTADOS: Houve aumento significativo de pacientes com controle pressórico (29%; P = 0,02), que cessaram tabagismo (18%; P = 0,003), e que receberam hipolipemiantes (19%; P < 0,0001) entre a internação para ICP e o primeiro retorno após o procedimento. Esse melhora do controle de fatores de risco refletiu-se em redução do escore de risco de Framingham médio observado no mesmo período (9,9%; P < 0,0001). Durante seguimento de até 12 meses o ganho atingido na internação para ICP se manteve para todos os fatores de risco. CONCLUSÕES: Observou-se efeito importante relativamente à internação índice para ICP, com aumento da prescrição de medicamentos para controle de fatores de risco e alcance de metas. Esse estudo identifica relevante janela de oportunidade para priorização do controle de fatores de risco na internação inicial, quando ganhos expressivos são observados e mantidos. Mas também explicita que esforços adicionais são necessários para expandir o benefício da prevenção secundária no seguimento a médio prazo de pacientes tratados por ICP.

BACKGROUND: Secondary prevention after percutaneous coronary intervention (PCI) is essential to increase event-free survival and consists mainly in risk factor control. We analyzed the secondary prevention of high-risk patients included prospectively in the Sequence Variation in Platelet Aggregation in Response to Clopidogrel and aspirin trial (SPARC). METHODS: From December 2009 to February 2011 we enrolled 187 consecutive patients who were submitted to PCI with stent implantation and were evaluated in outpatient visits at 1, 3, 6, and 12 months of follow-up for the control of hypertension, dysglycemia, hyperlipidemia and smoking and their respective therapeutic measures. RESULTS: There was a significant increase in the number of patients with controlled hypertension (29%; P = 0.02), who stopped smoking (18%; P = 0.003), and received statins (19%; P < 0.0001) between the index PCI and the first follow-up visit. The risk factor control improvement led to a decrease in the mean Framingham risk score (9.9%; P < 0.0001). During the 12 months follow-up the gains achieved at PCI admission were maintained for all risk factors. CONCLUSIONS: An important effect was observed on the index PCI admission with increased prescription of risk factor control drugs and achievement of therapeutic goals. This study identifies a relevant opportunity window for risk factor control at the index admission, when substantial gains are observed and maintained. However, it also shows further efforts are required to expand the benefit of secondary prevention in the middle-term follow-up of patients treated by PCI.

3248 downloads Citado 1 vez em SciELO

14.

Protoplast production and isolation from Etlingera elatior
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Silva Júnior, Jessé Marques da

; Paiva, Renato

; Campos, Ana Carolina Atala Lombelo

; Rodrigues, Marcelo

; Carvalho, Milene Alves de Figueiredo

; Otoni, Wagner Campos

Acta Scientiarum. Agronomy

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Mar 2012, Volume 34 Nº 1 Páginas 45 - 50

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Com o objetivo de realizar hibridações que auxiliam em programas de melhoramento genético de flores ornamentais, protoplastos foram isolados a partir de diferentes tecidos (folhas in vitro, pseudocaules in vitro e folhas em sistema hidropônico) de Etlnigera elatior (Jack) R. M. Smith. Foram testados seis diferentes combinações enzimáticas, quatro períodos de incubação, sistema rotatório (40 rpm) ou estacionário no escuro, concentrações de manitol (0,5; 0,6 e 0,7 M), o diâmetro e a viabilidade dos protoplastos isolados. A melhor fonte de explante utilizado no isolamento de protoplastos foi folha in vitro, com rendimento de 22 x10(5) protoplastos g-1 MF. O melhor tempo de incubação foi 15 horas, pois períodos superiores a este causavam diminuição no rendimento e viabilidade dos protoplastos. Protoplastos de folhas in vitro apresentaram viabilidade de 96% e diâmetro de 36,7 µm. Maiores rendimentos foram alcançados em sistema rotatório e no escuro. A melhor combinação enzimática utilizada no atual trabalho foi a 3% Cellulase “Onozuka” R-10 + 2% Meicelase + 1% Driselase + 1% Dextran + 5 mM MES. A melhor concentração de manitol foi de 0,6 M.

The technique of hybridization using plant protoplasts is widely used in plant breeding programs. The purpose of our study is to further characterize the process of protoplast isolation from the ornamental species Etlingera elatior (Jack) R. M. Smith. Protoplasts were isolated from different tissues: in vitro leaves, in vitro pseudostem, and leaves from plants cultivated hydroponically. We tested six enzymatic combinations, four incubation time periods, the rotary system (40 rpm) or steady in the dark, and three concentrations of mannitol (0.5, 0.6 and 0.7 M). The diameter and viability of obtained protoplasts were evaluated. The best source of explants used for protoplast isolation was the in vitro leaves, which yielded 22x10(5) protoplasts g-1 of fresh matter. The optimal incubation period was 15 hours. The in vitro leaves presented a greater viability (96%) and larger protoplasts (36.7 µm diameter). Greater yields were obtained using a rotatory system with protoplasts incubated in the dark. The best enzymatic combination was 3% Cellulase “Onozuca” R-10 + 2% Meicelase + 1% Driselase + 1% Dextran + 5 mM MES, followed by the addition of 0.6 M mannitol.

5933 downloads

15.

Spinal melanotic schwannomas
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Welling, Leonardo C.

; Guirado, Vinicius M. P.

; Tessari, Marcelo

; Felix, Alexandre R

; Zanellato, Cristina

; Figueiredo, Eberval G.

; Taricco, Mario Augusto

; Teixeira, Manoel Jacobsen

Arquivos de Neuro-Psiquiatria

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Fev 2012, Volume 70 Nº 2 Páginas 156 - 157

Resumo: En | Texto: En | PDF: En

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