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ABSTRACT: Canine parvovirus 2 (CPV-2) is a highly contagious enteric virus that causes high morbidity and mortality, especially in dogs under six months of age. Recovery from this illness is dependent on several factors, including the patient’s prognosis for adequate therapy. The aim of this study was to evaluate the risk factors associated with the death outcome in CPV-2 positive dogs in a case-control study conducted at the Veterinary Hospital of the Universidade Federal de Lavras (HV-UFLA) in Lavras, Minas Gerais, Brazil. Twenty-six dogs with CPV-2 symptoms that arrived at the HV-UFLA between 2017 and 2018 were evaluated for inclusion in the study. Data on medical history, clinical signs, blood count and rapid test of parvovirus and faecal test for polymerase chain reaction (PCR) were collected for all the animals. All the dogs received treatment at the HV-UFLA, and the overall fatality rate due to canine parvovirus was 30.77%. Descriptive analysis and univariate and multivariate statistical analyses (logistic regression) were performed to assess the variables that were possibly associated with an unfavourable prognosis (death). In the univariate and multivariate analyses, Systemic Inflammatory Response Syndrome (SIRS) was observed to be a significant risk factor for an unfavourable prognosis in canine parvovirus, as it increased the risk of death by 12.96 times (95% CI 1.85-133.70; P < 0.01) compared with patients who did not exhibit SIRS. Thus, SIRS was strongly associated with an unfavourable prognosis, suggesting that it can be used as a prognostic indicator for canine parvovirus in veterinary practice. ABSTRACT CPV2 CPV (CPV-2 mortality age patient s therapy CPV- casecontrol case control HVUFLA HV UFLA (HV-UFLA Gerais Brazil Twentysix Twenty 201 history signs PCR (PCR animals HVUFLA, UFLA, 3077 30 77 30.77% logistic regression death. . (death) (SIRS 1296 12 96 12.9 95% 95 (95 1.85133.70 18513370 1.85 133.70 1 85 133 70 1.85-133.70 0.01 001 0 01 Thus practice (CPV- 20 307 3 7 30.77 (death 129 9 12. (9 85133 1.85133.7 1851337 185 1.8 13370 133.7 8 13 1.85-133.7 0.0 00 (CPV 30.7 ( 8513 1.85133. 185133 18 1. 1337 133. 1.85-133. 0. 30. 851 1.85133 18513 1.85-133 1.8513 1851 1.85-13 1.851 1.85-1 1.85-

RESUMO: O parvovírus canino 2 (CPV-2) é um vírus entérico altamente contagioso que causa alta morbidade e mortalidade, principalmente em cães com menos de seis meses de idade. A recuperação desta doença é dependente de vários fatores, incluindo a determinação do prognóstico do paciente para terapia adequada. O objetivo deste estudo foi avaliar os fatores de risco associados ao desfecho óbito em cães com CPV-2 em um estudo de caso-controle realizado no Hospital Veterinário da Universidade Federal de Lavras (HV-UFLA), em Lavras, Minas Gerais. Vinte e seis cães com sintomas de CPV-2 que chegaram entre 2017 e 2018 ao HV-UFLA foram avaliados para inclusão no estudo. Dados sobre histórico médico, sinais clínicos, hemograma e teste rápido de parvovirose e fezes para reação em cadeia da polimerase (PCR) foram coletados para todos os animais. Todos os cães receberam tratamento estabelecido pelo HV-UFLA e a taxa geral de letalidade por parvovirose canina foi de 30,77%. Análise descritiva e análise estatística univariada e multivariada (regressão logística) foram utilizadas para avaliar variáveis possivelmente associadas a um prognóstico desfavorável (óbito). Na análise univariada e multivariada, a Síndrome da Resposta Inflamatória Sistêmica (SIRS) foi observada como fator de risco significativo para prognóstico desfavorável na parvovirose canina, pois aumentou 12,96 vezes o risco de morte (95% IC 1,85-133,70; P < 0,01) em comparação com aqueles pacientes que não apresentaram SIRS. Assim, a SIRS foi fortemente associada com um prognóstico desfavorável, sugerindo que pode ser utilizada como indicador prognóstico na parvovirose canina na prática veterinária. RESUMO CPV2 CPV (CPV-2 mortalidade idade adequada CPV- casocontrole caso controle HVUFLA, HVUFLA HV UFLA , (HV-UFLA) Gerais 201 médico clínicos PCR (PCR animais 3077 30 77 30,77% regressão logística óbito. . (óbito) (SIRS 1296 12 96 12,9 95% 95 (95 1,85133,70 18513370 1,85 133,70 1 85 133 70 1,85-133,70 0,01 001 0 01 Assim veterinária (CPV- (HV-UFLA 20 307 3 7 30,77 (óbito 129 9 12, (9 85133 1,85133,7 1851337 185 1,8 13370 133,7 8 13 1,85-133,7 0,0 00 (CPV 30,7 ( 8513 1,85133, 185133 18 1, 1337 133, 1,85-133, 0, 30, 851 1,85133 18513 1,85-133 1,8513 1851 1,85-13 1,851 1,85-1 1,85-

https://doi.org/10.1590/0103-8478cr20220517

Estresse e Enfrentamento das Dificuldades em Universitários da Área da Saúde
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Murakami, Karolina

; Santos, Jair Licio Ferreira dos

; Troncon, Luiz Ernesto de Almeida

; Panúncio-Pinto, Maria Paula

Psicologia: Ciência e Profissão

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2024, Volume 44 elocation e258748

Resumo: Es En Pt | Texto: Es En Pt | PDF: Es | PDF: En | PDF: Pt

Resumen: Este estudio pretende identificar la percepción de los estudiantes del sector salud sobre las dificultades académicas y no académicas, las estrategias de coping y la presencia de estrés. Este estudio transversal, con enfoque cuantitativo y cualitativo, utilizó cuestionarios estructurados e inventarios psicométricos validados (escala Brief COPE; inventario de sintomatología de estrés ISE ); además de entrevistas para ampliar la comprensión de los resultados de los instrumentos cuantitativos. En la etapa cuantitativa participaron 162 estudiantes de los cursos de grado en Fisioterapia, Fonoaudiología, Medicina, Nutrición y Terapia Ocupacional. De estos, 60 participaron en la entrevista cualitativa. Los resultados se sometieron a análisis estadístico univaria nte, para distinguir los grupos y asociaciones entre variables, y a análisis multivariado por regresión logística para identificar variables independientes que determinan el estrés. Los estudiantes reportaron enfrentar muchas dificultades académicas y no académicas, y utilizaban diferentes estrategias de coping. El análisis estadístico univariante no obtuvo diferencias significativas entre cursos y etapas respecto al número de dificultades y estrategias utilizadas. Un 45% y 100% de los estudiantes experimentaron estrés según el curso y la etapa considerada, sin diferencias significativas entre ellos. Se encontraron cinco variables independientes como factores de estrés: sexo femenino, renta familiar, número de dificultades académicas/no académicas y número de estrategias de coping orientadas a la “emoción”. El estrés patológico estuvo relacionado solo a la variable número de dificultades no académicas. Se necesita mantener acciones institucionales de asistencia social y apoyo psicológico para favorecer una planificación efectiva de medidas de promoción de salud mental de los estudiantes. Resumen transversal cualitativo escala COPE ) cuantitativos 16 Fisioterapia Fonoaudiología Medicina Ocupacional estos 6 cualitativa nte utilizadas 45 100 considerada ellos femenino familiar académicasno emoción. emoción . “emoción” 1 4 10 “emoción

Abstract: This study aimed to find undergraduate students’ perceptions about academic and non-academic difficulties and coping strategies and determining the occurrence of stress among them. This was a cross-sectional study using quantitative and qualitative approaches to evaluate students from different health professions in a single institution. Physical therapy, speech therapy, medicine, nutrition, and occupational therapy program students (N=162) answered a structured questionnaire and two validated psychometric inventories (COPE Brief scale and the ISS stress symptoms inventory). Additionally, 60 students underwent a semi-structured interview to better understand the results from the quantitative instruments. Quantitative data underwent univariate analysis to test differences between proportions and stepwise multiple regression analysis to identify the independent determinants of stress. Students reported a large number of academic and non-academic difficulties and a variety of coping strategies. Univariate statistical analysis showed no significant differences between courses and stages regarding the number of difficulties and coping strategies. A large proportion of students showed stress, ranging from 45% to 100%, depending on the course and stage, with no significant differences between them. Multivariate statistical analysis found five independent variables as stress determinants: female gender, low family income, number of academic and non-academic difficulties, and number of emotion-focused coping strategies. This analysis also showed that pathological stress is related to only one variable: the number of non-academic difficulties. These findings reinforce the importance of maintaining institutional actions for student social assistance and psychological support. Results also provide meaningful data for adequately planning more effective measures to promote students’ mental health. Abstract nonacademic non them crosssectional cross sectional institution medicine nutrition N=162 N162 N 162 (N=162 COPE inventory. inventory . inventory) Additionally 6 semistructured semi instruments 45 100 100% stage gender income emotionfocused emotion focused variable support N=16 N16 16 (N=16 4 10 N=1 N1 1 (N=1 N= (N= (N

Resumo: Este estudo pretende identificar a percepção de estudantes de uma mesma instituição de ensino superior da área da saúde sobre dificuldades acadêmicas e não acadêmicas, estratégias de coping e identificar a presença de estresse. Foi um estudo transversal utilizando abordagens quantitativa e qualitativa, desenvolvido por meio de questionário estruturado e inventários psicométricos validados ( COPE Breve; inventário de sintomas de estresse ISLL ). Adicionalmente, foram realizadas entrevistas para ampliar a compreensão dos resultados dos instrumentos quantitativos. Na etapa quantitativa, participaram 162 estudantes dos cursos de graduação em Fisioterapia, Fonoaudiologia, Medicina, Nutrição e Terapia Ocupacional. Destes, 60 participaram de entrevista qualitativa. Os dados foram submetidos à análise estatística univariada e análise multivariada por regressão logística. Os estudantes relataram encontrar grande número de dificuldades e utilizar variadas estratégias de coping . A análise estatística univariada demonstrou que não houve diferenças importantes entre cursos e etapas quanto ao número de dificuldades e estratégias utilizadas. A presença de estresse foi identificada em proporções entre 45% e 100% dos estudantes, conforme o curso e a etapa considerada, sem diferenças significativas entre eles. A análise multivariada identificou cinco variáveis independentes como determinantes de estresse: sexo feminino, renda familiar, número de dificuldades acadêmicas/não acadêmicas e número de estratégias de coping voltadas à “emoção” presentes. Esta análise também mostrou que o estresse patológico está relacionado a somente uma variável: o número de dificuldades não acadêmicas. Estes achados reforçam a necessidade de manter ações institucionais de assistência social e apoio psicológico, favorecendo assim um planejamento efetivo de medidas de promoção da saúde mental dos estudantes. Resumo qualitativa Breve ) Adicionalmente quantitativos 16 Fisioterapia Fonoaudiologia Medicina Ocupacional Destes 6 logística utilizadas 45 100 considerada eles feminino familiar acadêmicasnão emoção “emoção presentes variável psicológico 1 4 10

https://doi.org/10.1590/1982-3703003258748

First occurrence of feline sporotrichosis in a metropolitan area of Central-West Brazil CentralWest Central West
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Ferreira, Mariana Almeida

; Castilho, Allana de Paula

; Vargas, Gabrielle Silveira

; Patini, Bruna Elisa

; Moreira, André Luís Elias

; Santos, Jandra Pacheco dos

; Xavier, Roseli Santos de Freitas

; Del Negro, Gilda Maria Barbaro

; Taborda, Carlos Pelleschi

; Gremião, Isabella Dib

; Ferreira Júnior, Álvaro

Revista do Instituto de Medicina Tropical de São Paulo

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2024, Volume 66 elocation e19

Resumo: En | Texto: En | PDF: En

ABSTRACT Sporotrichosis is a neglected mycosis that affects human and animal hosts, including domestic cats. In Brazil, its most frequently diagnosed etiological agent is Sporothrix brasiliensis. Zoonotic transmission of S. brasiliensis occurs via direct contact between an infected cat and a susceptible human host. Notification of confirmed cases of feline sporotrichosis is not mandatory in Brazil. The metropolitan area of Goiania city can be considered a silent area for the occurrence of feline sporotrichosis. In this context, voluntary reporting of feline sporotrichosis cases is recommended for all healthcare professionals. This study aimed to report the first occurrence of S. brasiliensis in a cat from the metropolitan area of Goiania city. Cytopathology, mycology, thermal dimorphism and calmodulin gene amplification tests were performed. The mycological and molecular biological diagnoses corresponded to S. brasiliensis. The etiological agent of zoonotic sporotrichosis was detected in the metropolitan area of Goiania city, and therefore there is a risk of the emergence of new cases of cats infected with S. brasiliensis and the occurrence of zoonotic transmission of this fungus. hosts Brazil S host context professionals Cytopathology mycology performed fungus

https://doi.org/10.1590/s1678-9946202466019

Use of singular spectral analysis to reconstruct average monthly flow time series with complex behavior
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Bleidorn, Michel Trarbach

; Schmidt, Isamara Maria

; Reis, José Antonio Tosta dos

; Mendonça, Antônio Sérgio Ferreira

; Pinto, Wanderson de Paula

; Brasil, Gutemberg Hespanha

Revista Ambiente & Água

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2024, Volume 19 elocation e2946

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

Abstract Time series analysis is a useful tool for many practical water resource management applications, such as planning and anticipating conflict around water use. These analyses are also necessary for the use, design and operation of hydrotechnical works and for the protection of aquatic ecosystems. Basically, his review focuses on classic models such as Box and Jenkins. However, restrictive assumptions about data and residuals make its use difficult. As an alternative, non-parametric approaches are interesting due to their application versatility. One of the techniques that has been widely used in the analysis of flow time series is Singular Spectral Analysis (SSA). However, its application is concentrated as a pre-processor or in hybrid approaches and, because of this, many studies focus only on the model to be improved, leaving gaps in the process understanding that underlie the SSA. Within this context, and because of this, the objective of this study is to present the SSA technique in detail, through an application to a time series of monthly average flows with complex behavior (Jucu River, located in Southeast Brazil), in order to overcome gaps associated to a rigorous understanding of the procedures that make up the SSA. The Sequential SSA technique was used to decompose signal and noise components. The reconstructed series preserved the dynamics of the observed series, suggesting a strong influence of the signal component (trend and seasonality) on its behavior. It’s expected that the technique can be used with greater fluidity by specialists and contribute to the management of water resources. applications ecosystems Basically Jenkins However difficult alternative nonparametric non parametric versatility . (SSA) preprocessor pre processor improved context detail Jucu River Brazil, Brazil , Brazil) components trend seasonality Its It s resources (SSA

Resumo A análise de séries temporais é uma ferramenta útil para muitas aplicações práticas de gestão de recursos hídricos, como no planejamento e antecipação de conflitos em torno do uso d'água. Estas análises são também necessárias para a concepção e operação de obras hidrotécnicas e para a proteção de ecossistemas aquáticos. Basicamente, sua análise se concentra em modelos clássicos, como Box e Jenkins. No entanto, suposições restritivas sobre dados e resíduos dificultam seu uso. Como alternativa, abordagens não paramétricas são interessantes devido a sua versatilidade de aplicação. Uma das técnicas que têm sido amplamente utilizada na análise de séries temporais de vazão é a Análise Espectral Singular (SSA). No entanto, sua aplicação é concentrada como pré-processador ou em abordagens híbridas e por conta disso, muitos estudos se concentram apenas no modelo a ser aprimorado, deixando lacunas de entendimento dos processos que fundamentam a SSA. Dentro desse contexto, e por conta disso, o objetivo deste estudo é apresentar detalhadamente a técnica SSA, através de uma aplicação à uma série temporal de vazões médias mensais com comportamento complexo (rio Jucu, localizado no Sudeste do Brasil), a fim de superar lacunas associadas ao entendimento rigoroso dos procedimentos que compõem a SSA. A SSA Sequencial foi utilizada para decompor os componentes sinal e ruído. A série reconstruída preservou a dinâmica da série observada, sugerindo forte influência do sinal (tendência e sazonalidade) em seu comportamento. Espera-se que a técnica possa ser usada com maior fluidez pelos especialistas e contribuir na gestão dos recursos hídricos. hídricos dágua. dágua d água. água d'água aquáticos Basicamente clássicos Jenkins entanto alternativa . (SSA) préprocessador pré processador disso aprimorado contexto rio Jucu Brasil, Brasil , Brasil) ruído observada tendência sazonalidade Esperase Espera (SSA

https://doi.org/10.4136/ambi-agua.2946

Sorption isotherms of powdered cajá-manga pulp in different drying processes cajámanga cajá manga
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Lara Junior, Jovan Marques

; Ferreira, Ana Paula Rodrigues

; Afonso, Marcos Rodrigues Amorim

; Costa, José Maria Correia da

Revista Ciência Agronômica

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2024, Volume 55 elocation e20218245

Resumo: En | Texto: En | PDF: En

ABSTRACT High-sugar dehydrated foods have strong hygroscopicity, which can be avoided by using drying aids. One way to assess the hygroscopic behavior is through sorption isotherms. The objective of this work was to evaluate the influence of maltodextrin concentration on sorption isotherms of powdered cajá-manga pulp in spray-dryer, lyophilization and fluidized bed spray drying processes. The dryings were carried out in a spray-dryer, lyophilizer and fluidized bed, with 10%, 20% and 30% of maltodextrin. Adsorption isotherms were determined by the static gravimetric method using salt solutions for a relative humidity range of 21% to 90%. The GAB, BET, Henderson, and Oswin models were adequate to the experimental data. The relative deviation between the experimental values and the estimated values was calculated for each curve, in order to assess which equation best fit the experimental data. The mean relative error value of less than 10% was considered one of the criteria for selecting the models. The BET (A), BET (B) and GAB (C) models had the lowest error means, 3.35%, 3.35% and 5.28%, for cajá-manga powders obtained by spray-dryer, lyophilization and fluidized bed spray drying processes, respectively, and coefficients of determination above 0.99. It is concluded that the type of drying process did not influence the behavior of the adsorption isotherms, and that increases in maltodextrin concentration and temperature are significant in reducing equilibrium moisture contents. Highsugar High sugar hygroscopicity aids cajámanga cajá manga spraydryer, spraydryer dryer, dryer spray-dryer processes 10 20 30 21 90 90% Henderson data curve A, A , (A) B (B C (C means 335 3 35 3.35 528 5 28 5.28% respectively 099 0 99 0.99 contents 1 2 9 (A 33 3.3 52 5.28 09 0.9 3. 5.2 0. 5.

https://doi.org/10.5935/1806-6690.20240029

ENAM gene polymorphisms associated with dental anomalies in individuals with cleft lip and palate
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Oliveira, Fernanda Veronese de

; Santos, Carlos Ferreira dos

; Dionísio, Thiago José

; Neves, Lucimara Teixeira das

; Dalben, Gisele da Silva

; Ambrosio, Eloá Cristina Passucci

; Jorge, Paula Karine

; Machado, Maria Aparecida Andrade Moreira

; Oliveira, Thais Marchini

Brazilian Journal of Oral Sciences

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2024, Volume 23 elocation e241330

Resumo: En | Texto: En | PDF: En

Aim This study aimed to investigate the occurrence of enamelin gene (ENAM) single nucleotide polymorphisms (SNP) and ENAM polymorphism association with dental anomalies (DA) in individuals with unilateral or bilateral cleft lip and palate (CLP). Methods Saliva samples were collected from 147 individuals aged between 6 and 15 years-old, both genders, and divided into 4 groups: Group 1 (G1) - CLP and DA; Group 2 (G2) - CLP without DA; Group 3 (G3) - without CLP with DA; Group 4 (G4) - without CLP and DA. The genomic DNA was extracted from saliva samples and the following ENAM SNPs markers were genotyped: rs3796703, rs3796704, rs3796705, rs7671281, rs2609428, and rs35951442. Fisher exact and Pearson’s Chi-square tests statistically analyzed the results (α=5%). Results Individuals without CLP with DA (Group 3 - 19.2%) showed statistically higher prevalence of SNP rs2609428 heterozygotes (p=0.006) than individuals with CLP and DA (Group 1 - 0%). Individuals without CLP (10%) exhibited statistically higher prevalence of mutated heterozygotes/homozygous (p=0.028) than in individuals with CLP (1.3%). Conclusion SNP rs2609428 marker of ENAM gene may be associated with dental anomalies in individuals without cleft lip and palate. (ENAM (SNP (DA CLP. . (CLP) 14 yearsold, yearsold years old, old years-old genders groups G1 G (G1 G2 (G2 G3 (G3 G4 (G4 genotyped rs3796703 rs rs3796704 rs3796705 rs7671281 rs35951442 Pearsons Pearson s Chisquare Chi square α=5%. α5 α α=5% 5 (α=5%) 19.2% 192 19 rs260942 p=0.006 p0006 p 0 006 (p=0.006 0%. 0% 0%) 10% 10 (10% heterozygoteshomozygous homozygous p=0.028 p0028 028 (p=0.028 1.3%. 13 1.3% (1.3%) (CLP (G rs379670 rs767128 rs3595144 α=5 (α=5% 19.2 rs26094 p=0.00 p000 00 (p=0.00 (10 p=0.02 p002 02 (p=0.02 1.3 (1.3% rs37967 rs76712 rs359514 α= (α=5 19. rs2609 p=0.0 p00 (p=0.0 (1 1. (1.3 rs3796 rs7671 rs35951 (α= rs260 p=0. p0 (p=0. ( (1. rs379 rs767 rs3595 (α rs26 p=0 (p=0 rs37 rs76 rs359 rs2 p= (p= rs3 rs7 rs35 (p

https://doi.org/10.20396/bjos.v23i00.8671330

Psychometric properties and measurement invariance of the Herth Hope Index in Spanish cancer patients
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Calderon, Caterina

; Ferrando, Pere J

; Lorenzo-Seva, Urbano

; Ferreira, Estrella

; Sorribes, Elena

; Hernández, Raquel

; Planellas-Kircnher, Irina

; Mihic-Gongora, Luka

; J. Corral, Maria

; Jiménez-Fonseca, Paula

Psicothema

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2024, Volume 36 Nº 1 Páginas 72 - 79

Resumo: Es En | Texto: Es En | PDF: Es | PDF: En

Resumen: Antecedentes: El objetivo de este estudio fue evaluar las propiedades psicométricas, el funcionamiento de los ítems, la invariancia factorial y la validez convergente de la versión española del Herth Hope Index (HHI) en pacientes con cáncer. Método: Estudio transversal, multicéntrico, prospectivo de 863 pacientes con cáncer de 15 hospitales españoles. Se realizaron análisis factoriales exploratorios y confirmatorios para explorar la dimensionalidad, el funcionamiento de los ítems, la invariancia de medición según el sexo, la edad, el sitio del tumor y la supervivencia esperada, y la validez externa. Resultados: Los resultados obtenidos no respaldan la escala original de 3 factores y en cambio sugieren una estructura de un factor, que explicó el 62% de la varianza común, con una confiabilidad satisfactoria (ω = .88). Una solución de invariancia fuerte demostró un excelente ajuste en función del sexo, la edad, el sitio del tumor y la supervivencia. HHI reveló asociaciones sustanciales con la resiliencia y el bienestar espiritual. Conclusiones: Nuestros resultados indican que la versión en español del HHI es una herramienta corta, fácil de administrar, válida y confiable para evaluar el nivel de esperanza de los pacientes con cáncer.

Abstract: Background: The aim of this study was to evaluate the psychometric properties, differential item functioning, factorial invariance, and convergent validity of the Spanish version of the Herth Hope Index (HHI) in patients with cancer. Method: Exploratory and confirmatory factor analyses were conducted to explore the scale, dimensionality, functioning of items, test for strong measurement invariance across sex, age, tumor site, and expected survival, and an extended structural equation model to assess external validity in a cross-sectional, multicenter, prospective study of 863 cancer patients from 15 Spanish hospitals. Results: The results do not support the original 3-factor scale but instead suggest a one-factor structure, which explained 62% of the common variance. Scores from the unidimensional structure exhibited satisfactory reliability (ω = .88). A strong invariance solution demonstrated excellent fit across sex, age, tumor site, and survival. HHI exhibited substantial associations with resilience coping strategies and spiritual well-being. Conclusions: The findings of our study contribute to the diversity of earlier empirical findings regarding the construct of hope. Despite this, our results indicate that the Spanish version of the HHI is a short, easy-to-administer, valid, reliable tool for evaluating cancer patients' levels of hope.

https://doi.org/10.7334/psicothema2023.86

Impacto da Covid-19 na prática de automedicação em estudantes universitários Covid19 Covid 19 Covid-1 Covid1 1 Covid-
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Cecilio, Samyra Giarola

; Vargas, Maria Eduarda Carvalho

; Silveira, Ana Paula Vital

; Cecilio, Sumaya Giarola

; Coelho, Jasiara Carla de Oliveira

; Silva, Douglas Roberto Guimarães

; Taranto, Martinelle Ferreira da Rocha

; Resende, Thainá Richelli Oliveira

Trabalho, Educação e Saúde

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2024, Volume 22 elocation e02368235

Resumo: Es En Pt | Texto: Es En Pt | PDF: Es | PDF: En | PDF: Pt

Resumen La automedicación expone a los individuos a riesgos tales como reacciones adversas, intoxicaciones, interacciones medicamentosas, fracasos terapéuticos y errores medicamentosos. En la pandemia de Covid-19, hubo un aumento en la compra y consumo de productos farmacéuticos por parte de los brasileños. El presente estudio tuvo como objetivo estimar la prevalencia y los factores asociados a la automedicación en estudiantes de un centro universitario en la región de Campo das Vertentes, Sudeste de Brasil, así como evaluar la incidencia durante la pandemia de Covid-19. El estudio tuvo un diseño transversal y cuantitativo, con 248 estudiantes de un centro universitario en 2021. Los hallazgos mostraron que el 67,3% de los participantes reportaron automedicación; el 28,7% indicó un aumento en la automedicación durante la pandemia; y el 30,9% indicó el inicio en este período. Hubo una diferencia significativa en: Considerarse capaz de automedicarse, tener el hábito de referir drogas a otras personas y consumirlas por indicación de otros. Para aquellos que incrementaron la práctica de la automedicación en la pandemia, hubo una asociación con el hábito de indicar drogas a otras personas. Para aquellos que iniciaron esta práctica en el período pandémico, se asoció la capacidad de automedicación. Los resultados abren caminos para medidas educativas sobre el uso irracional de medicamentos por parte de los estudiantes de educación superior, independientemente del área de formación. adversas intoxicaciones medicamentosas medicamentosos Covid19, Covid19 Covid 19, 19 Covid-19 brasileños Vertentes Brasil Covid19. 19. cuantitativo 24 2021 673 67 3 67,3 287 28 7 28,7 309 30 9 30,9 automedicarse otros pandémico superior formación Covid1 1 Covid-1 2 202 6 67, 28, 30, Covid- 20

Abstract Self-medication exposes individuals to risks such as adverse reactions, intoxications, drug interactions, therapeutic failures and medication errors. In the COVID-19 pandemic, there was an increase in the purchase and consumption of pharmaceutical products by Brazilians. The present study aimed to estimate the prevalence and factors associated with self-medication in students of a university center in the region of Campo das Vertentes, Southeastern Brazil, as well as to evaluate the incidence during the COVID-19 pandemic. The study had a cross-sectional and quantitative design, with 248 students from a university, in 2021. The findings showed that 67.3% of the participants reported self-medication; 28.7% indicated an increase in self-medication during the pandemic; and 30.9% indicated the beginning in this period. There was a significant difference about: to consider oneself capable of self-medicating, to have the habit of referring drugs to other people and to consume them by indication of others. For those who increased the practice of self-medication in the pandemic, there was an association with the habit of indicating drugs to other people. For those who initiated this practice in the pandemic period, the capacity of self-medication was associated. The results open paths for educational measures on the irrational use of medicines by higher education students, regardless of the education area. Selfmedication Self reactions intoxications interactions errors COVID19 COVID 19 COVID-1 Brazilians selfmedication self Vertentes Brazil crosssectional cross sectional design 24 2021 673 67 3 67.3 287 28 7 28.7 309 30 9 30.9 period about selfmedicating, selfmedicating medicating, medicating self-medicating others area COVID1 1 COVID- 2 202 6 67. 28. 30. 20

Resumo A automedicação expõe os indivíduos a riscos como reações adversas, intoxicações, interações medicamentosas, falhas terapêuticas e erros de medicação. Na pandemia de Covid-19, houve aumento de compra e consumo de produtos farmacêuticos pelos brasileiros. O presente estudo teve como objetivo estimar a prevalência e os fatores associados à automedicação em estudantes de um centro universitário na região do Campo das Vertentes, Minas Gerais, bem como avaliar a incidência durante a pandemia de Covid-19. O estudo teve delineamento transversal e quantitativo, com 248 estudantes de um centro universitário em 2021. Os achados mostraram que 67,3% dos participantes relataram realizar a automedicação; 28,7% apontaram aumento da automedicação durante a pandemia; e 30,9% indicaram o início nesse período. Houve diferença significativa sobre: considerar-se capaz de se automedicar, ter costume de indicar medicamentos para outras pessoas e consumi-los por indicação de outros. Para aqueles que aumentaram a prática de automedicação na pandemia, houve associação com o hábito de indicar medicamentos para outras pessoas. Já para quem iniciou essa prática no período pandêmico, a capacidade de automedicação esteve associada. Os resultados abrem caminhos para medidas educativas sobre o uso irracional dos medicamentos pelos estudantes do ensino superior, independentemente da área de formação. adversas intoxicações medicamentosas medicação Covid19, Covid19 Covid 19, 19 Covid-19 brasileiros Vertentes Gerais Covid19. 19. quantitativo 24 2021 673 67 3 67,3 287 28 7 28,7 309 30 9 30,9 considerarse considerar automedicar consumilos consumi los outros pandêmico associada superior formação Covid1 1 Covid-1 2 202 6 67, 28, 30, Covid- 20

https://doi.org/10.1590/1981-7746-ojs2368

Immunogenicity of COVID-19 adsorbed inactivated vaccine (CoronaVac) and additional doses of mRNA BNT162b2 vaccine in immunocompromised adults compared with immunocompetent persons COVID19 COVID 19 COVID-1 CoronaVac (CoronaVac BNTb BNT b BNT162b COVID1 1 COVID-
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Ibrahim, Karim Yaqub

; Moreira, Raquel Megale

; Santos, Carolina Ferreira dos

; Strabelli, Tânia Mara Varejão

; Belizário, Juliana de Cássia

; Pinto, Maria Isabel de Moraes

; Marinho, Ana Karolina Barreto Berselli

; Pereira, Juliana Marquezi

; Mello, Liliane Saraiva de

; Ando, Mauricio Cesar

; Silva, Vitor Gabriel Lopes da

; Sato, Paula Keiko

; Lima, Marcos Alves de

; França, João Italo Dias

; Loch, Ana Paula

; Miyaji, Karina Takesaki

; Infante, Vanessa

; Precioso, Alexander Roberto

; Sartori, Ana Marli Christovam

Revista do Instituto de Medicina Tropical de São Paulo

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2024, Volume 66 elocation e24

Resumo: En | Texto: En | PDF: En

ABSTRACT Inactivated COVID-19 vaccines data in immunocompromised individuals are scarce. This trial assessed the immunogenicity of two CoronaVac doses and additional BNT162b2 mRNA vaccine doses in immunocompromised (IC) and immunocompetent (H) individuals. Adults with solid organ transplant (SOT), hematopoietic stem cell transplant, cancer, inborn immunity errors or rheumatic diseases were included in the IC group. Immunocompetent adults were used as control group for comparison. Participants received two CoronaVac doses within a 28-day interval. IC received two additional BNT162b2 doses and H received a third BNT162b2 dose (booster). Blood samples were collected at baseline, 28 days after each dose, pre-booster and at the trial end. We used three serological tests to detect antibodies to SARS-CoV-2 nucleocapsid (N), trimeric spike (S), and receptor binding domain (RBD). Outcomes included seroconversion rates (SCR), geometric mean titers (GMT) and GMT ratio (GMTR). A total of 241 IC and 100 H adults participated in the study. After two CoronaVac doses, IC had lower SCR than H: anti-N, 33.3% vs 79%; anti-S, 33.8% vs 86%, and anti-RBD, 48.5% vs 85%, respectively. IC also showed lower GMT than H: anti-N, 2.3 vs 15.1; anti-S, 58.8 vs 213.2 BAU/mL; and anti-RBD, 22.4 vs 168.0 U/mL, respectively. After the 3rd and 4th BNT162b2 doses, IC had significant anti-S and anti-RBD seroconversion, but still lower than H after the 3rd dose. After boosting, GMT increased in IC, but remained lower than in the H group. CoronaVac two-dose schedule immunogenicity was lower in IC than in H. BNT162b2 heterologous booster enhanced immune response in both groups. COVID19 COVID 19 COVID-1 scarce BNTb BNT b BNT162b (IC (H SOT, SOT , (SOT) cancer comparison 28day day interval booster. . (booster) baseline 2 prebooster pre end SARSCoV2 SARSCoV SARS CoV SARS-CoV- N, N (N) S, S (S) RBD. RBD (RBD) SCR, (SCR) (GMT GMTR. GMTR (GMTR) 24 10 study antiN, antiN anti anti-N 333 33 3 33.3 79% 79 antiS, antiS 338 8 33.8 86 86% antiRBD, antiRBD RBD, 485 48 5 48.5 85 85% respectively 23 2. 15.1 151 15 1 588 58 58. 2132 213 213. BAU/mL BAUmL BAU mL 224 22 4 22. 1680 168 0 168. UmL U U/mL rd th boosting twodose groups COVID1 COVID- (SOT (booster SARS-CoV (N (S (RBD (SCR (GMTR 33. 7 48. 15. 21 16

https://doi.org/10.1590/s1678-9946202466024

10.

Atypical bacterial respiratory infections in children
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Barros, Paula Barros de

; Xavier, Luiza Fernandes

; Herter, Eduardo da Costa

; Fernandes, Maria Fernanda Gonçalves Meirelles

; Ferreira, Isabel Cristina Schütz

; Pinto, Leonardo Araujo

Jornal Brasileiro de Pneumologia

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2024, Volume 50 Nº 2 elocation e20240126

Resumo: En | Texto: En | PDF: En

https://doi.org/10.36416/1806-3756/e20240126

11.

Leishmania (Sauroleishmania) tarentolae versus pathogenic species: comparative evaluation of protease activity, glycoconjugates, resistance to complement and metabolome composition Sauroleishmania (Sauroleishmania species activity glycoconjugates
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Andrade, Filipe Fideles Duarte

; Vitório, Jéssica Gardone

; Canuto, Gisele André Baptista

; Nunes, Fernanda Freire Campos

; Rodrigues, Isabela Aurora

; Almeida, Ana Paula Martins Morais

; Nascimento, Frederico Crepaldi

; Costa, Adriana Oliveira

; Vieira, Tamara da Silva

; Silva, Ana Carolina Carvalho

; André, Leiliane Coelho

; Gontijo, Célia Maria Ferreira

; Junqueira, Caroline

; Toledo, Juliano Simões de

; Fernandes, Ana Paula

; Soares, Rodrigo Pedro

Memórias do Instituto Oswaldo Cruz

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2024, Volume 119 elocation e230243

Resumo: En | Texto: En | PDF: En

BACKGROUND Leishmania tarentolae is a non-pathogenic species found in lizards representing an important model for Leishmania biology. However, several aspects of this Sauroleishmania remain unknown to explain its low level of virulence. OBJECTIVES We reported several aspects of L. tarentolae biology including glycoconjugates, proteolytic activities and metabolome composition in comparison to pathogenic species (Leishmania amazonensis, Leishmania braziliensis, Leishmania infantum and Leishmania major). METHODS Parasites were cultured for extraction and purification of lipophosphoglycan (LPG), immunofluorescence probing with anti-gp63 and resistance against complement. Parasite extracts were also tested for proteases activity and metabolome composition. FINDINGS Leishmania tarentolae does not express LPG on its surface. It expresses gp63 at lower levels compared to pathogenic species and, is highly sensitive to complement-mediated lysis. This species also lacks intracellular/extracellular activities of proteolytic enzymes. It has metabolic differences with pathogenic species, exhibiting a lower abundance of metabolites including ABC transporters, biosynthesis of unsaturated fatty acids and steroids, TCA cycle, glycine/serine/threonine metabolism, glyoxylate/dicarboxylate metabolism and pentose-phosphate pathways. MAIN CONCLUSIONS The non-pathogenic phenotype of L. tarentolae is associated with alterations in several biochemical and molecular features. This reinforces the need of comparative studies between pathogenic and non-pathogenic species to elucidate the molecular mechanisms of virulence during host-parasite interactions. nonpathogenic non However L glycoconjugates amazonensis braziliensis major. major . major) LPG, , (LPG) antigp63 antigp anti gp anti-gp6 complement surface gp6 complementmediated mediated lysis intracellularextracellular intracellular extracellular enzymes transporters steroids cycle glycineserinethreonine glycine serine threonine glyoxylatedicarboxylate glyoxylate dicarboxylate pentosephosphate pentose phosphate pathways features hostparasite host parasite interactions (LPG antigp6 anti-gp

https://doi.org/10.1590/0074-02760230243

12.

High PD-L1 expression is associated with unfavorable clinical features in myelodysplastic neoplasms PDL1 PDL PD L1 L PD-L
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Sampaio, Leticia Rodrigues

; Viana, Mateus de Aguiar

; Oliveira, Vanessa Silva de

; Ferreira, Bruna Vitoriano

; Melo, Mayara Magna Lima

; Oliveira, Roberta Taiane Germano de

; Borges, Daniela de Paula

; Magalhãesa, Silvia Maria Meira

; Pinheiro, Ronald F.

Hematology, Transfusion and Cell Therapy

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2024, Volume 46 Nº 2 Páginas 146 - 152

Resumo: En | Texto: En | PDF: En

ABSTRACT Introduction: Immune checkpoints are regulators of the immune system response that allow self-tolerance. Molecules such as Programmed Cell Death Protein 1 (PD-1) and its Ligand (PD-L1) participate in the immune checkpoint by signaling co-inhibition of lymphocyte responses. In cancers, PD-L1 expression is associated with the immune evasion mechanism, which favors tumor growth. The use of anti-PD-1/PD-L1 drugs is already well described in solid tumors, but still not fully understood in hematologic malignancies. Myelodysplastic neoplasms (MDSs) are heterogeneous bone marrow disorders with an increased risk of progression to Acute Myeloid Leukemia (AML). The MDS affects hematopoietic stem cells and its pathogenesis is linked to genetic and epigenetic defects, in addition to immune dysregulation. The influence of the PD-L1 on the MDS remains unknown. Methods: In this study, we evaluated the mRNA expression of the PD-L1 in 53 patients with MDS, classified according to the WHO 2016 Classification. Results: Patients with dyserythropoiesis presented significantly higher PD-L1 expression than patients without dyserythropoiesis (p = 0.050). Patients classified as having MDS with an excess of blasts 2 (MDS-EB2) presented a significant upregulation in the mRNA expression of the PD-L1 compared to the MDS with an excess of blasts 1 (MDS-EB1) (p = 0.050). Furthermore, we detected three patients with very high levels of PD-L1 expression, being statistically classified as outliers. Conclusion: We suggested that the high expression of the PD-L1 is associated with a worse prognosis in the MDS and functional studies are necessary to evaluate the possible use of anti-PD-L1 therapies for high-risk MDS, such as the MDS-EBs. Introduction selftolerance. selftolerance self tolerance. tolerance self-tolerance PD1 PD (PD-1 PDL1 PDL L1 L (PD-L1 coinhibition co inhibition responses cancers PD-L mechanism growth antiPD1/PDL1 antiPD1PDL1 antiPDPDL anti 1/PD anti-PD-1/PD-L tumors malignancies MDSs (MDSs AML. AML . (AML) defects dysregulation unknown Methods study 5 201 Classification Results p 0.050. 0050 0.050 0 050 0.050) MDSEB2 MDSEB EB2 EB (MDS-EB2 MDSEB1 EB1 (MDS-EB1 Furthermore outliers Conclusion antiPDL1 antiPDL anti-PD-L highrisk MDSEBs. MDSEBs EBs. EBs MDS-EBs (PD- (PD-L antiPD1 antiPD antiPD1/PDL antiPD1PDL 1PD (AML 20 005 0.05 05 (MDS-EB (PD 00 0.0 0.

https://doi.org/10.1016/j.htct.2023.05.002

13.

Safety of CoronaVac and ChAdOx1 vaccines against SARS-CoV-2 in patients with rheumatoid arthritis: data from the Brazilian multicentric study safer ChAdOx SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- arthritis SARS-CoV
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Cruz, Vitor Alves

; Guimarães, Camila

; Rêgo, Jozelia

; Machado, Ketty Lysie Libardi Lira

; Miyamoto, Samira Tatiyama

; Burian, Ana Paula Neves

; Dias, Laiza Hombre

; Pretti, Flavia Zon

; Batista, Danielle Cristina Filgueira Alves

; Mill, José Geraldo

; Oliveira, Yasmin Gurtler Pinheiro de

; Gadelha, Carolina Strauss Estevez

; Gouveia, Maria da Penha Gomes

; Moulin, Anna Carolina Simões

; Souza, Bárbara Oliveira

; Aguiar, Laura Gonçalves Rodrigues

; Vieira, Gabriel Smith Sobral

; Grillo, Luiza Lorenzoni

; Lima, Marina Deorce de

; Pasti, Laís Pizzol

; Surlo, Heitor Filipe

; Faé, Filipe

; Moulaz, Isac Ribeiro

; Macabú, Mariana de Oliveira

; Ribeiro, Priscila Dias Cardoso

; Magalhães, Vanessa de Oliveira

; Aguiar, Mariana Freitas de

; Biegelmeyer, Erika

; Peixoto;, Flávia Maria Matos Melo Campos

; Kayser, Cristiane

; Souza, Alexandre Wagner Silva de

; Castro, Charlles Heldan de Moura

; Ribeiro, Sandra Lúcia Euzébio

; Telles, Camila Maria Paiva França

; Bühring, Juliana

; Lima, Raquel Lima de

; Santos, Sérgio Henrique Oliveira Dos

; Dias, Samuel Elias Basualto

; Melo, Natália Seixas de

; Sanches, Rosely Holanda da Silva

; Boechat, Antonio Luiz

; Sartori, Natália Sarzi

; Hax, Vanessa

; Dória, Lucas Denardi

; Rezende, Rodrigo Poubel Vieira de

; Baptista, Katia Lino

; Fortes, Natália Rodrigues Querido

; Melo, Ana Karla Guedes de

; Melo, Tâmara Santos

; Vieira, Rejane Maria Rodrigues de Abreu

; Vieira, Adah Sophia Rodrigues

; Kakehasi, Adriana Maria

; Tavares, Anna Carolina Faria Moreira Gomes

; Landa, Aline Teixeira de

; Costa, Pollyana Vitoria Thomaz da

; Azevedo, Valderilio Feijó

; Martins-Filho, Olindo Assis

; Peruhype-Magalhães, Vanessa

; Pinheiro, Marcelo de Medeiros

; Monticielo, Odirlei André

; Reis-neto, Edgard Torres Dos

; Ferreira, Gilda Aparecida

; Souza, Viviane Angelina de

; Teixeira-Carvalho, Andréa

; Xavier, Ricardo Machado

; Sato, Emilia Inoue

; Valim, Valeria

; Pileggi, Gecilmara Salviato

; Silva, Nilzio Antonio da

Advances in Rheumatology

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2024, Volume 64 elocation 58

Resumo: En | Texto: En | PDF: En

Abstract Background Patients with immune-mediated rheumatic diseases (IMRDs) have been prioritized for COVID-19 vaccination to mitigate the infection severity risks. Patients with rheumatoid arthritis (RA) are at a high risk of severe COVID-19 outcomes, especially those under immunosuppression or with associated comorbidities. However, few studies have assessed the safety of the COVID-19 vaccine in patients with RA. Objective To evaluate the safety of vaccines against SARS-CoV-2 in patients with RA. Methods This data are from the study “Safety and Efficacy on COVID-19 Vaccine in Rheumatic Diseases,” a Brazilian multicentric prospective phase IV study to evaluate COVID-19 vaccine in IMRDs in Brazil. Adverse events (AEs) in patients with RA of all centers were assessed after two doses of ChAdOx1 (Oxford/AstraZeneca) or CoronaVac (Sinovac/Butantan). Stratification of postvaccination AEs was performed using a diary, filled out daily and returned at the end of 28 days for each dose. Results A total of 188 patients with RA were include, 90% female. CoronaVac was used in 109 patients and ChAdOx1 in 79. Only mild AEs were observed, mainly after the first dose. The most common AEs after the first dose were pain at the injection (46,7%), headache (39,4%), arthralgia (39,4%), myalgia (30,5%) and fatigue (26,6%), and ChAdOx1 had a higher frequency of pain at the injection (66% vs 32 %, p < 0.001) arthralgia (62% vs 22%, p < 0.001) and myalgia (45% vs 20%, p < 0.001) compared to CoronaVac. The more common AEs after the second dose were pain at the injection (37%), arthralgia (31%), myalgia (23%), headache (21%) and fatigue (18%). Arthralgia (41,4% vs 25%, p = 0.02) and pain at injection (51,4% vs 27%, p = 0.001) were more common with ChAdOx1. No serious AEs were related. With Regard to RA activity level, no significant difference was observed between the three time periods for both COVID-19 vaccines. Conclusion In the comparison between the two immunizers in patients with RA, local reactions and musculoskeletal symptoms were more frequent with ChAdOx1 than with CoronaVac, especially after the first dose. In summary, the AE occurred mainly after the first dose, and were mild, like previous data from others immunizing agents in patients with rheumatoid arthritis. Vaccination did not worsen the degree of disease activity. immunemediated immune mediated (IMRDs COVID19 COVID 19 COVID-1 risks (RA outcomes comorbidities However SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- Safety Diseases, Diseases Brazil (AEs ChAdOx Oxford/AstraZeneca OxfordAstraZeneca Oxford AstraZeneca (Oxford/AstraZeneca Sinovac/Butantan. SinovacButantan Sinovac/Butantan . Sinovac Butantan (Sinovac/Butantan) diary 18 include 90 female 10 79 46,7%, 467 46,7% , 46 7 (46,7%) 39,4%, 394 39,4% 39 4 (39,4%) 30,5% 305 30 5 (30,5% 26,6%, 266 26,6% 26 6 (26,6%) 66% 66 (66 3 % 0.001 0001 0 001 62% 62 (62 22 22% 45% 45 (45 20 20% 37%, 37 37% (37%) 31%, 31 31% (31%) 23%, 23 23% (23%) 21% 21 (21% 18%. 18% (18%) 41,4% 414 41 (41,4 25 25% 0.02 002 02 51,4% 514 51 (51,4 27 27% related level summary COVID1 1 COVID- SARS-CoV (Sinovac/Butantan 9 46,7 (46,7% 39,4 (39,4% 30,5 (30,5 26,6 (26,6% (6 0.00 000 00 (4 (37% (31% (23% (21 (18% 41,4 (41, 0.0 51,4 (51, 46, (46,7 39, (39,4 30, (30, 26, (26,6 ( (37 (31 (23 (2 (18 41, (41 0. 51, (51 (46, (39, (30 (26, (3 (1 (5 (46 (39 (26

https://doi.org/10.1186/s42358-024-00397-5

14.

Clinical signs of bruxism in CrossFit® practitioners: observational study CrossFit practitioners
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RIBEIRO, Igor Ferreira Batista

; LIEUTHIER, Karina Miranda

; FERREIRA, Gabriela De Sena

; PASSOS, Vanara Florêncio

; PEIXOTO, Raniel Fernandes

; NOGUEIRA, Sandra Maria Abreu

; ONGARO, Paula Jordani

; FIAMENGUI, Lívia Maria Sales Pinto

Dental Press Journal of Orthodontics

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2024, Volume 29 Nº 5 elocation e242476

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO Introdução: O CrossFit® é um método de treinamento físico que visa promover a aptidão física por meio do desenvolvimento de componentes como capacidade aeróbia, força e resistência muscular. Os dados sobre comportamentos de bruxismo em praticantes de CrossFit® são escassos, mas estudos prévios mostraram aumento do comportamento de apertamento dentário durante as práticas de levantamento de peso. Objetivo: O presente estudo teve como objetivo avaliar os sinais clínicos de bruxismo em praticantes de CrossFit®. Métodos: O estudo foi composto por uma amostra de conveniência de praticantes de CrossFit® (n=57), de ambos os sexos, com idade entre 19 e 58 anos, e as variáveis de desfecho foram: Lista de Verificação de Comportamento Oral, Questionário Internacional de Atividade Física e Ferramenta Padronizada para Avaliação do Bruxismo. Os dados foram expressos em termos de valores absolutos e percentuais. Para análise estatística, foram utilizados os testes de correlação de Spearman e exato de Fisher, e considerou-se nível de significância de 5%. Resultados: A média de idade foi de 32,82 anos, com maioria feminina (63,15%). Os praticantes de CrossFit® relataram frequentemente apertar os dentes durante a prática do treinamento (61,40%) e apresentaram linha alba (82,45%), impressão labial (54,38%), impressão de língua (26,31%), exostose óssea (19,29%), desgaste dentário (61,40%) e lesões cervicais não cariosas (35,09%). Conclusões: Não foi encontrada correlação entre sinais clínicos de bruxismo, comportamentos orais e intensidade da atividade física; no entanto, os resultados sugerem que indivíduos que praticam o treinamento CrossFit® apresentam comportamentos orais que podem causar alterações morfofuncionais no sistema estomatognático, principalmente o hábito de apertar os dentes durante o treinamento. Além disso, os dados enfatizam a necessidade de educação em saúde bucal entre os praticantes de CrossFit®, sendo necessários mais estudos com amostras representativas. Introdução CrossFit aeróbia muscular escassos peso Objetivo Métodos n=57, n57 n n=57 , 57 (n=57) sexos 1 5 anos Oral Bruxismo percentuais estatística Fisher considerouse considerou se 5% Resultados 3282 32 82 32,8 63,15%. 6315 63,15% . 63 15 (63,15%) 61,40% 6140 61 40 (61,40% 82,45%, 8245 82,45% 45 (82,45%) 54,38%, 5438 54,38% 54 38 (54,38%) 26,31%, 2631 26,31% 26 31 (26,31%) 19,29%, 1929 19,29% 29 (19,29%) 35,09%. 3509 35,09% 35 09 (35,09%) Conclusões entanto estomatognático disso representativas n5 n=5 (n=57 328 3 8 32, 631 63,15 6 (63,15% 61,40 614 4 (61,40 824 82,45 (82,45% 543 54,38 (54,38% 263 26,31 2 (26,31% 192 19,29 (19,29% 350 35,09 0 (35,09% n= (n=5 63,1 (63,15 61,4 (61,4 82,4 (82,45 54,3 (54,38 26,3 (26,31 19,2 (19,29 35,0 (35,09 (n= 63, (63,1 61, (61, 82, (82,4 54, (54,3 26, (26,3 19, (19,2 35, (35,0 (n (63, (61 (82, (54, (26, (19, (35, (63 (6 (82 (54 (26 (19 (35 ( (8 (5 (2 (1 (3

ABSTRACT Introduction: CrossFit® is a physical training method that aims to promote physical fitness through the development of components such as aerobic capacity, strength and muscular endurance. Data regarding bruxism behaviors in CrossFit® practitioners are scarce, but previous studies have shown increased dental clenching behavior during weightlifting practices. Objective: The present study aimed to evaluate clinical signs of bruxism in CrossFit® practitioners. Methods: The sample comprised a convenience sample of CrossFit® practitioners (n=57), of both genders, aged 19-58 years. Outcome variables were as follows: Oral Behavior Checklist, the International Physical Activity Questionnaire and the Standardized Tool for the Assessment of Bruxism. Data were expressed in terms of absolute values and percentages. Spearman’s correlation and Fisher exact tests were used for statistical analysis, and a significance level of 5% was considered. Results: The mean age was 32.82 years, with a female majority (63.15%). CrossFit® practitioners frequently reported clenching their teeth during training practice (61.40%) and presented linea alba (82.45%), lip impression (54.38%), tongue impression (26.31%), bone exostosis (19.29%), tooth wear (61.40%) and non-carious cervical lesions (35.09%). Conclusions: No correlation was found between clinical signs of bruxism, oral behaviors and physical activity intensity; however, the results suggest that individuals who practice CrossFit® training have oral behaviors that can cause morpho-functional changes in the stomatognathic system, especially the habit of clenching their teeth during training. In addition, data emphasize the need for dental health education among CrossFit® practitioners, and more studies with a representative sample are necessary. Introduction CrossFit capacity endurance scarce practices Objective Methods n=57, n57 n n=57 , 57 (n=57) genders 1958 19 58 19-5 years follows Checklist Bruxism percentages Spearmans Spearman s analysis 5 considered Results 3282 32 82 32.8 63.15%. 6315 63.15% . 63 15 (63.15%) 61.40% 6140 61 40 (61.40% 82.45%, 8245 82.45% 45 (82.45%) 54.38%, 5438 54.38% 54 38 (54.38%) 26.31%, 2631 26.31% 26 31 (26.31%) 19.29%, 1929 19.29% 29 (19.29%) noncarious non carious 35.09%. 3509 35.09% 35 09 (35.09%) Conclusions intensity however morphofunctional morpho functional system addition necessary n5 n=5 (n=57 195 1 19- 328 3 8 32. 631 63.15 6 (63.15% 61.40 614 4 (61.40 824 82.45 (82.45% 543 54.38 (54.38% 263 26.31 2 (26.31% 192 19.29 (19.29% 350 35.09 0 (35.09% n= (n=5 63.1 (63.15 61.4 (61.4 82.4 (82.45 54.3 (54.38 26.3 (26.31 19.2 (19.29 35.0 (35.09 (n= 63. (63.1 61. (61. 82. (82.4 54. (54.3 26. (26.3 19. (19.2 35. (35.0 (n (63. (61 (82. (54. (26. (19. (35. (63 (6 (82 (54 (26 (19 (35 ( (8 (5 (2 (1 (3

https://doi.org/10.1590/2177-6709.29.5.e242476.oar

15.

Vygotsky’s concept of emotion: the indissociability of affective and cognitive aspects in human development Vygotskys Vygotsky s emotion
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Faria, Paula Maria Ferreira de

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2024, Volume 41 elocation e230058

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

Abstract Objective This article presents a diachronic review of Lev Vygotsky’s concept of emotion and its significance in understanding human development. Method The article has a theoretical methodology and emphasizes the importance of situating the analysis of emotions within the context of human work and the meanings attributed to it. Results Vygotsky’s innovative approach transcends the traditional dichotomy between emotion and cognition, emphasizing the integrated nature of human experience. His concept of higher psychological functions highlights the cultural-historical context in which these functions are developed, forming the basis for projecting collective social interactions into individual psychological processes. The author argues that emotions are fundamental to personality development and self-regulation, shaped by cultural influences. Conclusion While Vygotsky did not provide precise definitions of emotion and feeling, his work underscores their dynamic and transformative nature. Emotions, as dynamic elements of personality, contribute to the construction of the individual’s psychological life and influence social interactions. Vygotskys s it cognition experience culturalhistorical historical developed processes selfregulation, selfregulation self regulation, regulation self-regulation influences feeling Emotions individuals

Resumo Objetivo Este artigo revisa o conceito de emoção de Lev Vigotski e sua relevância no desenvolvimento humano. Método Este artigo assume uma metodologia teórico e ressalta a importância de situar a análise das emoções no contexto do trabalho humano e nos significados atribuídos a ele. Resultados A abordagem inovadora de Vigotski vai além da dicotomia tradicional entre emoção e cognição, destacando a natureza integrada da experiência humana. Sua concepção de funções psicológicas superiores enfatiza o contexto sociocultural em que se desenvolvem, projetando as interações sociais coletivas nos processos psicológicos individuais. O autor argumenta que as emoções desempenham um papel essencial no desenvolvimento da personalidade e na autorregulação, influenciadas por fatores culturais. Conclusão Embora Vigotski não defina emoção e sentimento com precisão, seu trabalho destaca sua natureza dinâmica e transformadora. As emoções, como elementos dinâmicos da personalidade, contribuem para a construção da vida psicológica do indivíduo e influenciam as interações sociais. ele cognição humana desenvolvem individuais autorregulação culturais precisão transformadora

https://doi.org/10.1590/1982-0275202441e230058

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