Pesquisa | SciELO

Fernandes, Fabio Simões, Marcus V. Correia, Edileide de Barros Marcondes-Braga, Fabiana G. Coelho-Filho, Otavio Rizzi Mesquita, Cláudio Tinoco Mathias-Junior, Wilson Rochitte, Carlos Eduardo Ramires, Felix José Alvarez Alves, Silvia Marinho Martins Montera, Marcelo Westerlund Lopes, Renato Delascio Oliveira-Junior, Mucio Tavares Scolari, Fernando L. Avila, Walkiria Samuel Canesin, Manoel Fernandes Bacal, Fernando Bocchi, Edimar Alcides Moura, Lídia Ana Zytynski Saad, Eduardo Benchimol Scanavacca, Mauricio I. Valdigem, Bruno Pereira Cano , Manuel Nicolas Abizaid , Alexandre Ribeiro, Henrique Barbosa Lemos-Neto, Pedro Alves Ribeiro, Gustavo Calado de Aguiar Jatene, Fabio Biscegli Dias, Ricardo Ribeiro Beck-da-Silva, Luis Rohde, Luis Eduardo P. Bittencourt, Marcelo Imbroinise Pereira, Alexandre Krieger, José Eduardo Villacorta, Humberto Martins, Wolney de Andrade Figueiredo-Neto, José Albuquerque de Cardoso , Juliano Novaes Pastore, Carlos Alberto Jatene, Ieda Biscegli Tanaka, Ana Cristina Sayuri Hotta, Viviane Tiemi Romano, Minna Moreira Dias Albuquerque, Denilson Campos de Mourilhe-Rocha, Ricardo Hajjar, Ludhmila Abrahão Brito, Fabio Sandoli de Caramelli , Bruno Calderaro, Daniela Farsky, Pedro Silvio Colafranceschi , Alexandre Siciliano Pinto, Ibraim Masciarelli Vieira , Marcelo Luiz Campos Danzmann, Luiz Claudio Barberato , Silvio Henrique Mady, Charles Martinelli-Filho, Martino Torbey , Ana Flavia Malheiros Schwartzmann, Pedro Vellosa Macedo, Ariane Vieira Scarlatelli Ferreira , Silvia Moreira Ayub Schmidt, Andre Melo , Marcelo Dantas Tavares de Lima-Filho, Moysés Oliveira Sposito, Andrei C. Brito, Flavio de Souza Biolo, Andreia Madrini-Junior, Vagner Rizk, Stéphanie Itala Mesquita, Evandro Tinoco

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Data de publicação: 2024-04-08

Resumo: Pt Es En

A cardiomiopatia hipertrófica (CMH) é uma forma de doença do músculo cardíaco de causa genética, caracterizada pela hipertrofia das paredes ventriculares. O diagnóstico requer detecção por métodos de imagem (Ecocardiograma ou Ressonância Magnética Cardíaca) de qualquer segmento da parede do ventrículo esquerdo com espessura > 15 mm, sem outra causa provável. A análise genética permite identificar mutações de genes codificantes de diferentes estruturas do sarcômero responsáveis pelo desenvolvimento da CMH em cerca de 60% dos casos, permitindo o rastreio de familiares e aconselhamento genético, como parte importante do manejo dos pacientes e familiares. Vários conceitos sobre a CMH foram recentemente revistos, incluindo sua prevalência de 1 em 250 indivíduos, não sendo, portanto, uma doença rara, mas subdiagnosticada. A vasta maioria dos pacientes é assintomática. Naqueles sintomáticos, a obstrução do trato de saída do ventrículo esquerdo (OTSVE) é o principal distúrbio responsável pelos sintomas, devendo-se investigar a sua presença em todos os casos. Naqueles em que o ecocardiograma em repouso ou com Manobra de Valsalva não detecta gradiente intraventricular significativo (> 30 mmHg), devem ser submetidos à ecocardiografia com esforço físico para detecção da OTSVE.   Pacientes com sintomas limitantes e grave OTSVE, refratários ao uso de betabloqueadores e verapamil, devem receber terapias de redução septal ou uso de novas drogas inibidoras da miosina cardíaca. Por fim, os pacientes adequadamente identificados com risco aumentado de morta súbita podem receber medida profilática com implante de cardiodesfibrilador implantável (CDI).

La miocardiopatía hipertrófica (MCH) es una forma de enfermedad cardíaca de origen genético, caracterizada por el engrosamiento de las paredes ventriculares. El diagnóstico requiere la detección mediante métodos de imagen (Ecocardiograma o Resonancia Magnética Cardíaca) que muestren algún segmento de la pared ventricular izquierda con un grosor > 15 mm, sin otra causa probable. El análisis genético permite identificar mutaciones en genes que codifican diferentes estructuras del sarcómero responsables del desarrollo de la MCH en aproximadamente el 60% de los casos, lo que permite el tamizaje de familiares y el asesoramiento genético, como parte importante del manejo de pacientes y familiares. Varios conceptos sobre la MCH han sido revisados recientemente, incluida su prevalencia de 1 entre 250 individuos, por lo tanto, no es una enfermedad rara, sino subdiagnosticada. La gran mayoría de los pacientes son asintomáticos. En los casos sintomáticos, la obstrucción del tracto de salida ventricular izquierdo (TSVI) es el trastorno principal responsable de los síntomas, y su presencia debe investigarse en todos los casos. En aquellos en los que el ecocardiograma en reposo o la maniobra de Valsalva no detecta un gradiente intraventricular significativo (> 30 mmHg), deben someterse a ecocardiografía de esfuerzo para detectar la obstrucción del TSVI. Los pacientes con síntomas limitantes y obstrucción grave del TSVI, refractarios al uso de betabloqueantes y verapamilo, deben recibir terapias de reducción septal o usar nuevos medicamentos inhibidores de la miosina cardíaca. Finalmente, los pacientes adecuadamente identificados con un riesgo aumentado de muerte súbita pueden recibir medidas profilácticas con el implante de un cardioversor-desfibrilador implantable (CDI).

Hypertrophic cardiomyopathy (HCM) is a form of genetically caused heart muscle disease, characterized by the thickening of the ventricular walls. Diagnosis requires detection through imaging methods (Echocardiogram or Cardiac Magnetic Resonance) showing any segment of the left ventricular wall with a thickness > 15 mm, without any other probable cause. Genetic analysis allows the identification of mutations in genes encoding different structures of the sarcomere responsible for the development of HCM in about 60% of cases, enabling screening of family members and genetic counseling, as an important part of patient and family management. Several concepts about HCM have recently been reviewed, including its prevalence of 1 in 250 individuals, hence not a rare but rather underdiagnosed disease. The vast majority of patients are asymptomatic. In symptomatic cases, obstruction of the left ventricular outflow tract (LVOT) is the primary disorder responsible for symptoms, and its presence should be investigated in all cases. In those where resting echocardiogram or Valsalva maneuver does not detect significant intraventricular gradient (> 30 mmHg), they should undergo stress echocardiography to detect LVOT obstruction. Patients with limiting symptoms and severe LVOT obstruction, refractory to beta-blockers and verapamil, should receive septal reduction therapies or use new drugs inhibiting cardiac myosin. Finally, appropriately identified patients at increased risk of sudden death may receive prophylactic measure with implantable cardioverter-defibrillator (ICD) implantation.

https://doi.org/10.1590/SciELOPreprints.8394

Gastric adenocarcinoma and periodontal disease: A systematic review and meta-analysis disease metaanalysis meta analysis
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Aguiar, Francisco José Nunes

; Menezes, Fabrício dos Santos

; Fagundes, Marcela de Araújo

; Fernandes, Gisele Aparecida

; Alves, Fabio de Abreu

; Goncalves Filho, João

; Curado, Maria Paula

Clinics

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2024, Volume 79 elocation 100321

Resumo: En | Texto: En | PDF: En

Abstract Background The oral cavity is a link between of external environment with gastrointestinal tract. Studies are controversial on the presence of Periodontal Disease (PD) and its association with Gastric Adenocarcinoma (GAC). Methods The authors performed a systematic review and meta-analysis to verify the association between PD and GAC. Six electronic databases were evaluated between 1961 and 2022. Titles and abstracts were reviewed independently according to the eligibility criteria, assessing full texts of selected studies. The quality of the included research was verified using the Newcastle-Ottawa Scale for case-control and cohort studies. Statistical analyses were performed based on fixed and/or random effects models to calculate the summarized Relative Risk (RR) and its 95 % Confidence Interval (95 % CI). Results There were 639 studies, of which nine articles were included (3 case-controls and 6 cohorts). Overall, the authors identified 1,253 cases of GAC 2,501 controls in case-control studies, and 1,631 patients with GAC enrolled in cohort studies. Patients presenting PD increased the risk of developing GAC by 17 % (RR=1.17; 95 % CI 1.03‒1.32), which remained regardless of the diagnostic method for PD, i.e., clinical examination (RR = 1.19; 95 % CI 1.14‒1.24) and self-report (RR = 1.34; 95 % CI 1.06‒1.69). Moreover, Asian patients (RR=1.17; 95 % CI 1.00‒1.36) with PD had a higher risk of having GAC than American and European patients (RR = 1.18; 95 % CI 0.84‒1.66). Conclusions The presence of PD the risk of GAC suggesting that its infectious-inflammatory process of PD may be related to GAC development. Further investigations on the oral-gastric microbiota and its role in the carcinogenesis of gastric cancer should be carried out, and the screening of patients with potential risk for GAC should be considered in the clinical practice of dentists. tract (PD . (GAC) metaanalysis meta analysis 196 2022 criteria studies NewcastleOttawa Newcastle Ottawa casecontrol case control andor or RR 9 (9 CI. CI) 63 3 ( casecontrols cohorts. cohorts cohorts) Overall 1253 1 253 1,25 2501 2 501 2,50 1631 631 1,63 RR=1.17 RR117 (RR=1.17 1.03‒1.32, 103132 1.03‒1.32 , 03 32 1.03‒1.32) ie i e i.e. 1.19 119 19 1.14‒1.24 114124 14 24 selfreport self report 1.34 134 34 1.06‒1.69. 106169 1.06‒1.69 06 69 1.06‒1.69) Moreover 1.00‒1.36 100136 00 36 1.18 118 18 0.84‒1.66. 084166 0.84‒1.66 0 84 66 0.84‒1.66) infectiousinflammatory infectious inflammatory development oralgastric out dentists (GAC 202 125 25 1,2 250 50 2,5 163 1,6 RR=1.1 RR11 (RR=1.1 10313 1.03‒1.3 i.e 1.1 11 1.14‒1.2 11412 1.3 13 10616 1.06‒1.6 1.00‒1.3 10013 08416 0.84‒1.6 8 20 12 1, 5 2, 16 RR=1. RR1 (RR=1. 1031 1.03‒1. 1. 1.14‒1. 1141 1061 1.06‒1. 1.00‒1. 1001 0841 0.84‒1. RR=1 (RR=1 103 1.03‒1 1.14‒1 114 106 1.06‒1 1.00‒1 100 084 0.84‒1 RR= (RR= 10 1.03‒ 1.14‒ 1.06‒ 1.00‒ 08 0.84‒ 1.03 1.14 1.06 1.00 0.84 1.0 0.8 0.

https://doi.org/10.1016/j.clinsp.2023.100321

A preliminary study of cutaneous wound healing on the upper eyelid in a small Brazilian population using Rhizophora mangle-based cream manglebased mangle based
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SILVA, JERRAR J.X.

; LEAL, LEILA B.

; SÁ, JÉSSICA G.A.

; SABINO, LARISSA R.A.

; CAVALCANTI, ISABELLE M.F.S.D.

; SILVA, LUZIA A.

; SANTANA, EDUARDA S. DE

; FERNANDES, FERNANDO HENRIQUE P.

; C. FILHO, IRANILDO JOSÉ

; BRANDÃO, WESLEY F.M.

; VIEIRA, JEYMESSON RAPHAEL C.

Anais da Academia Brasileira de Ciências

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2024, Volume 96 Nº 1 elocation e20231143

Resumo: En | Texto: En | PDF: En

Abstract Plants used in traditional medicine offer an affordable new alternative in tissue repair therapy. This study aimed to evaluate the effectiveness of the 5% Rhizophora mangle cream compared to the 5% dexpanthenol cream in healing open surgical wounds on the upper eyelid. A total of 18 patients were submitted to the experiment and divided into 2 groups with 9 patients each who used topically and daily 5% dexpanthenol cream (control group) or 5% R.mangle cream (intervention group) for 7 days. Clinical, morphometric and histomorphometric analyses of wounds and surgical procedures for skin removal were performed. In the morphometric analysis, all wounds treated with R.mangle and dexpanthenol creams showed complete macroscopic scars, without inflammatory signs and infection free. The skin hydration values in pre and post application periods of the cream were 43.82 ± 43.93 and 62.12 ± 67.40 respectively. The histomorphometric study showed lower values of epithelium distance in R. mangle group and higher in dexpanthenol group with significant difference between groups (p < 0.05). The R.mangle 5% cream proved to be effective in healing wounds of human upper eyelid skin with a significant improvement in epithelization compared to dexpanthenol 5% cream. therapy 5 1 control Rmangle R intervention days Clinical performed analysis scars free 4382 43 82 43.8 4393 93 43.9 6212 62 12 62.1 6740 67 40 67.4 respectively p 0.05. 005 0.05 . 0 05 0.05) 438 4 8 43. 439 621 6 62. 674 67. 00 0.0 0.

https://doi.org/10.1590/0001-3765202420231143

Encefalomielite aguda disseminada com provável etiologia de Bartonella henselae
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Ferreira, Kauê Marques

; Araújo Filho, José Laércio de

; Nogueira, Priscilla Fernandes

Revista Brasileira de Oftalmologia

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2024, Volume 83 elocation e0008

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

ABSTRACT Acute disseminated encephalomyelitis is a rare, acute, inflammatory, and demyelinating disease of the central nervous system. Presumably associated in more than three quarters of cases by infections (viral, bacterial, or nonspecific) and immunizations or without any identifiable antecedent. It usually presents a monophasic course with onset of nonspecific symptoms in the prodromal phase and may evolve with multifocal neurological changes and even visual acuity loss. We describe a case of a 9-year-old boy with an initial picture of papillary edema caused by acute disseminated encephalomyelitis due to Bartonella henselae. Despite the severity of the disease, early diagnosis and treatment provided good outcomes. rare inflammatory system viral, viral (viral bacterial antecedent loss 9yearold yearold 9 year old henselae outcomes

RESUMO A encefalomielite aguda disseminada é uma doença rara, aguda, inflamatória e desmielinizante do sistema nervoso central, presumivelmente associada, em mais de três quartos dos casos, a infecções (virais, bacterianas ou inespecíficas) e imunizações ou sem qualquer antecedente indentificável. Habitualmente, apresenta um curso monofásico com início de sintomas inespecíficos na fase prodrómica, podendo evoluir com alterações neurológicas multifocais e até à perda total da acuidade visual. Descrevemos o caso de um menino de 9 anos com quadro inicial de edema de papila causado por encefalomielite aguda disseminada devido a Bartonella henselae. Apesar da gravidade da doença, o diagnóstico e o tratamento precoce proporcionaram bons desfechos. rara central associada casos virais, virais (virais inespecíficas indentificável Habitualmente prodrómica visual henselae desfechos

https://doi.org/10.37039/1982.8551.20240008

TNF-α promoter hypomethylation is frequent in oncopediatric patients who recovered from mucositis TNFα TNF α
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VIANA FILHO, José Maria Chagas

; CASTRO COÊLHO, Marina de

; QUEIROZ NETO, José Nunes de

; SOUZA, Beatriz Fernandes de

; VALENÇA, Ana Maria Gondim

; OLIVEIRA, Naila Francis Paulo de

Brazilian Oral Research

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2024, Volume 38 elocation e042

Resumo: En | Texto: En | PDF: En

Abstract The aim of this study was to investigate the DNA methylation profile in genes encoding catalase (CAT) and superoxide dismutase (SOD3) enzymes, which are involved in oxidative stress mechanisms, and in genes encoding pro-inflammatory cytokines interleukin-6 (IL6) and tumor necrosis factor-alpha (TNF-α) in the oral mucosa of oncopediatric patients treated with methotrexate (MTX®). This was a cross-sectional observational study and the population comprised healthy dental patients (n = 21) and those with hematological malignancies (n = 64) aged between 5 and 19 years. Oral conditions were evaluated using the Oral Assessment Guide and participants were divided into 4 groups: 1- healthy individuals; 2- oncopediatric patients without mucositis; 3- oncopediatric patients with mucositis; 4- oncopediatric patients who had recovered from mucositis. Methylation of DNA from oral mucosal cells was evaluated using the Methylation-Specific PCR technique (MSP). For CAT, the partially methylated profile was the most frequent and for SOD3 and IL6, the hypermethylated profile was the most frequent, with no differences between groups. For TNF-α, the hypomethylated profile was more frequent in the group of patients who had recovered from mucositis. It was concluded that the methylation profiles of CAT, SOD3, and IL6 are common profiles for oral cells of children and adolescents and have no association with oral mucositis or exposure to chemotherapy with MTX®. Hypomethylation of TNF-α is associated with oral mucosal recovery in oncopediatric patients who developed oral mucositis during chemotherapy. CAT (CAT SOD (SOD3 enzymes mechanisms proinflammatory pro inflammatory interleukin6 interleukin 6 interleukin- IL (IL6 factoralpha factor alpha TNFα TNF α (TNF-α MTX MTX® . (MTX®) crosssectional cross sectional n 21 64 1 years groups individuals 2 3 MethylationSpecific Specific MSP. MSP (MSP) TNFα, α, (SOD (IL (MTX® (MSP (MTX

https://doi.org/10.1590/1807-3107bor-2024.vol38.0042

Brazilian Consensus on the Application of Thermal Ablation for Treatment of Thyroid Nodules: A Task Force Statement by the Brazilian Society of Interventional Radiology and Endovascular Surgery (SOBRICE), Brazilian Society of Head and Neck Surgery (SBCCP), and Brazilian Society of Endocrinology and Metabolism (SBEM) Nodules SOBRICE, SOBRICE , (SOBRICE) SBCCP, SBCCP (SBCCP) SBEM (SBEM (SOBRICE (SBCCP
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Santos, Gustavo Philippi de los

; Kulcsar, Marco Aurélio Vamondes

; Capelli, Fabio de Aquino

; Steck, Jose Higino

; Fernandes, Klecius Leite

; Mesa Junior, Cleo Otaviano

; Motta-Leal-Filho, Joaquim Mauricio da

; Scheffel, Rafael Selbach

; Vaisman, Fernanda

; Martins, Guilherme Lopes Pinheiro

; Szejnfeld, Denis

; Amoedo, Mauricio Kauark

; Menezes, Marcos Roberto de

; Rahal Junior, Antonio

; Matos, Leandro Luongo

Archives of Endocrinology and Metabolism

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2024, Volume 68 elocation e230263

Resumo: En | Texto: En | PDF: En

ABSTRACT There is increasing interest in ultrasound-guided ablation treatments for thyroid diseases, including benign and malignant ones. Surgeons, radiologists, and endocrinologists carry out these treatments, and various organizations within these specialties have recently released multiple international consensus statements and clinical practice standards. The aim of the present consensus statement is to provide guidance, cohesion, and standardization of best practices for thermal ablation procedures of thyroid nodules. The statement includes the indications for these procedures, preprocedural evaluations, technical aspects of the procedures, posttreatment care, follow-up, complications, and training recommendations. This document was written by a panel of specialists from the Brazilian Society of Interventional Radiology and Endovascular Surgery (SOBRICE), the Brazilian Society of Head and Neck Surgery (SBCCP), and the Brazilian Society of Endocrinology and Metabolism (SBEM). The statement does not aim to provide criteria for assessing the capability of specialists to perform the procedure. Instead, it aims to promote the standardization of best practices to reduce potential adverse outcomes. Additionally, it strives to enhance the delivery of high-quality care and the widespread adoption of these technologies on a national level. The recommendations collectively serve as a guidebook for applying best practices in thyroid ablation. ultrasoundguided ultrasound guided diseases ones Surgeons radiologists standards guidance cohesion nodules evaluations followup, followup follow up, up follow-up complications SOBRICE, SOBRICE , (SOBRICE) SBCCP, SBCCP (SBCCP) SBEM. SBEM . (SBEM) procedure Instead outcomes Additionally highquality high quality level (SOBRICE (SBCCP (SBEM

https://doi.org/10.20945/2359-4292-2023-0263

Diretriz sobre Diagnóstico e Tratamento da Cardiomiopatia Hipertrófica – 2024 202 20 2
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Fernandes, Fabio

; Simões, Marcus V.

; Correia, Edileide de Barros

; Marcondes-Braga, Fabiana Goulart

; Coelho-Filho, Otavio Rizzi

; Mesquita, Cláudio Tinoco

; Mathias Junior, Wilson

; Antunes, Murillo de Oliveira

; Arteaga-Fernández, Edmundo

; Rochitte, Carlos Eduardo

; Ramires, Felix José Alvarez

; Alves, Silvia Marinho Martins

; Montera, Marcelo Westerlund

; Lopes, Renato Delascio

; Oliveira Junior, Mucio Tavares de

; Scolari, Fernando Luis

; Avila, Walkiria Samuel

; Canesin, Manoel Fernandes

; Bocchi, Edimar Alcides

; Bacal, Fernando

; Moura, Lidia Zytynski

; Saad, Eduardo Benchimol

; Scanavacca, Mauricio Ibrahim

; Valdigem, Bruno Pereira

; Cano, Manuel Nicolas

; Abizaid, Alexandre Antonio Cunha

; Ribeiro, Henrique Barbosa

; Lemos Neto, Pedro Alves

; Ribeiro, Gustavo Calado de Aguiar

; Jatene, Fabio Biscegli

; Dias, Ricardo Ribeiro

; Beck-da-Silva, Luis

; Rohde, Luis Eduardo Paim

; Bittencourt, Marcelo Imbroinise

; Pereira, Alexandre da Costa

; Krieger, José Eduardo

; Villacorta Junior, Humberto

; Martins, Wolney de Andrade

; Figueiredo Neto, José Albuquerque de

; Cardoso, Juliano Novaes

; Pastore, Carlos Alberto

; Jatene, Ieda Biscegli

; Tanaka, Ana Cristina Sayuri

; Hotta, Viviane Tiemi

; Romano, Minna Moreira Dias

; Albuquerque, Denilson Campos de

; Mourilhe-Rocha, Ricardo

; Hajjar, Ludhmila Abrahão

; Brito Junior, Fabio Sandoli de

; Caramelli, Bruno

; Calderaro, Daniela

; Farsky, Pedro Silvio

; Colafranceschi, Alexandre Siciliano

; Pinto, Ibraim Masciarelli Francisco

; Vieira, Marcelo Luiz Campos

; Danzmann, Luiz Claudio

; Barberato, Silvio Henrique

; Mady, Charles

; Martinelli Filho, Martino

; Torbey, Ana Flavia Malheiros

; Schwartzmann, Pedro Vellosa

; Macedo, Ariane Vieira Scarlatelli

; Ferreira, Silvia Moreira Ayub

; Schmidt, Andre

; Melo, Marcelo Dantas Tavares de

; Lima Filho, Moysés Oliveira

; Sposito, Andrei C.

; Brito, Flávio de Souza

; Biolo, Andreia

; Madrini Junior, Vagner

; Rizk, Stephanie Itala

; Mesquita, Evandro Tinoco

Arquivos Brasileiros de Cardiologia

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2024, Volume 121 Nº 7 elocation e202400415

Resumo: Pt | Texto: Pt | PDF: Pt

https://doi.org/10.36660/abc.20240415

How can we reduce maternal mortality due to preeclampsia? The 4P rule preeclampsia P
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Korkes, Henri Augusto

; Cavalli, Ricardo Carvalho

; Oliveira, Leandro Gustavo De

; Ramos, José Geraldo Lopes

; Martins Costa, Sérgio Hofmeister de Almeida

; Sousa, Francisco Lázaro Pereira de

; Vieira da Cunha Filho, Edson

; de Souza Mesquita, Maria Rita

; Dias Corrêa Júnior, Mário

; Pinheiro Fernandes Araújo, Ana Cristina

; Zaconeta, Alberto Carlos Moreno

; Freire, Carlos Henrique Esteves

; Poli de Figueiredo, Carlos Eduardo

; Rocha Filho, Edilberto Alves Pereira da

; Sass, Nelson

; Peraçoli, José Carlos

; Costa, Maria Laura

Revista Brasileira de Ginecologia e Obstetrícia

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2024, Volume 46 elocation e-rbgo43

Resumo: En | Texto: En | PDF: En

Abstract In low and middle-income countries such as Brazil, most maternal deaths are related to hypertensive complications. Preeclampsia is the leading cause of maternal mortality and morbidity. Significant proportion is associated with the following factors: lack of identification of high-risk women, lack of adequate prevention, difficulty in maintaining a high-risk prenatal follow-up, delayed diagnosis, insecurity and low use of magnesium sulphate, delayed pregnancy interruption and lack of postpartum follow-up of these high-risk cases. Four major actions are proposed to minimize this alarming clinical picture and reduce the mortality rates due to preeclampsia, called the "4 P Rule" (Adequate Prevention – Vigilant Prenatal Care – Timely Delivery (Parturition) – Safe Postpartum). From this simple "rule" we can open a range of important processes and reminders that may help in the guidance of preeclampsia management. middleincome middle income Brazil complications morbidity factors highrisk high risk women prevention followup, followup follow up, up diagnosis sulphate cases 4 " Rule Adequate Parturition (Parturition Postpartum. Postpartum . Postpartum) rule "rule management

https://doi.org/10.61622/rbgo/2024rbgo43

Posicionamento do Departamento de Imagem Cardiovascular da Sociedade Brasileira de Cardiologia sobre o Uso do Strain Miocárdico na Rotina do Cardiologista – 2023 202 20 2
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Almeida, André Luiz Cerqueira

; Melo, Marcelo Dantas Tavares de

; Bihan, David Costa de Souza Le

; Vieira, Marcelo Luiz Campos

; Pena, José Luiz Barros

; Del Castillo, José Maria

; Abensur, Henry

; Hortegal, Renato de Aguiar

; Otto, Maria Estefania Bosco

; Piveta, Rafael Bonafim

; Dantas, Maria Rosa

; Assef, Jorge Eduardo

; Beck, Adenalva Lima de Souza

; Santo, Thais Harada Campos Espirito

; Silva, Tonnison de Oliveira

; Salemi, Vera Maria Cury

; Rocon, Camila

; Lima, Márcio Silva Miguel

; Barberato, Silvio Henrique

; Rodrigues, Ana Clara

; Rabschkowisky, Arnaldo

; Frota, Daniela do Carmo Rassi

; Gripp, Eliza de Almeida

; Barretto, Rodrigo Bellio de Mattos

; Silva, Sandra Marques e

; Cauduro, Sanderson Antonio

; Pinheiro, Aurélio Carvalho

; Araujo, Salustiano Pereira de

; Tressino, Cintia Galhardo

; Silva, Carlos Eduardo Suaide

; Monaco, Claudia Gianini

; Paiva, Marcelo Goulart

; Fisher, Cláudio Henrique

; Alves, Marco Stephan Lofrano

; Grau, Cláudia R. Pinheiro de Castro

; Santos, Maria Veronica Camara dos

; Guimarães, Isabel Cristina Britto

; Morhy, Samira Saady

; Leal, Gabriela Nunes

; Soares, Andressa Mussi

; Cruz, Cecilia Beatriz Bittencourt Viana

; Guimarães Filho, Fabio Villaça

; Assunção, Bruna Morhy Borges Leal

; Fernandes, Rafael Modesto

; Saraiva, Roberto Magalhães

; Tsutsui, Jeane Mike

; Soares, Fábio Luis de Jesus

; Falcão, Sandra Nívea dos Reis Saraiva

; Hotta, Viviane Tiemi

; Armstrong, Anderson da Costa

; Hygidio, Daniel de Andrade

; Miglioranza, Marcelo Haertel

; Camarozano, Ana Cristina

; Lopes, Marly Maria Uellendahl

; Cerci, Rodrigo Julio

; Siqueira, Maria Eduarda Menezes de

; Torreão, Jorge Andion

; Rochitte, Carlos Eduardo

; Felix, Alex

Arquivos Brasileiros de Cardiologia

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Dez 2023, Volume 120 Nº 12 elocation e20230646

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

https://doi.org/10.36660/abc.20230646

10.

Brazilian Black Women are at Higher Risk for COVID-19 Complications: An Analysis of REBRACO, a National Cohort COVID19 COVID 19 COVID-1 Complications REBRACO COVID1 1 COVID-
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Dantas-Silva, Amanda

; Surita, Fernanda Garanhani

; Souza, Renato

; Rocha, Leila

; Guida, José Paulo

; Pacagnella, Rodolfo

; Tedesco, Ricardo

; Fernandes, Karayna

; Martins-Costa, Sérgio

; Peret, Frederico

; Feitosa, Francisco

; Traina, Evelyn

; Cunha Filho, Edson

; Vettorazzi, Janete

; Haddad, Samira

; Andreucci, Carla

; Correa Junior, Mario

; Dias, Marcos

; Oliveira, Leandro de

; Melo Junior, Elias

; Luz, Marília

; Cecatti, Jose Guilherme

; Costa, Maria Laura

Revista Brasileira de Ginecologia e Obstetrícia

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Mai 2023, Volume 45 Nº 5 Páginas 253 - 260

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

Abstract Objective To evaluate the impact of the race (Black versus non-Black) on maternal and perinatal outcomes of pregnant women with COVID-19 in Brazil. Methods This is a subanalysis of REBRACO, a Brazilian multicenter cohort study designed to evaluate the impact of COVID-19 on pregnant women. From February2020 until February 2021, 15 maternity hospitals in Brazil collected data on women with respiratory symptoms. We selected all women with a positive test for COVID-19; then, we divided them into two groups: Black and non-Black women. Finally, we compared, between groups, sociodemographic, maternal, and perinatal outcomes. We obtained the frequency of events in each group and compared them using X2 test; p-values < 0.05 were considered significant. We also estimated the odds ratio (OR) and confidence intervals (CI). Results 729 symptomatic women were included in the study; of those, 285 were positive for COVID-19, 120 (42.1%) were Black, and 165 (57.9%) were non-Black. Black women had worse education (p = 0.037). The timing of access to the health system was similar between both groups, with 26.3% being included with seven or more days of symptoms. Severe acute respiratory syndrome (OR 2.22 CI 1.17–4.21), intensive care unit admission (OR 2.00 CI 1.07–3.74), and desaturation at admission (OR 3.72 CI 1.41–9.84) were more likely to occur among Black women. Maternal death was higher among Black women (7.8% vs. 2.6%, p = 0.048). Perinatal outcomes were similar between both groups. Conclusion Brazilian Black women were more likely to die due to the consequences of COVID-19. nonBlack non COVID19 COVID 19 COVID-1 REBRACO February202 2021 1 symptoms then groups Finally sociodemographic X pvalues values 005 0 05 0.0 significant OR CI. . (CI) 72 those 28 COVID19, 19, 12 42.1% 421 42 (42.1% 16 57.9% 579 57 9 (57.9% nonBlack. Black. 0.037. 0037 0.037 037 0.037) 263 26 3 26.3 222 2 22 2.2 1.17–4.21, 117421 1.17–4.21 , 17 4 21 1.17–4.21) 200 00 2.0 1.07–3.74, 107374 1.07–3.74 07 74 1.07–3.74) 372 3.7 1.41–9.84 141984 41 84 7.8% 78 7 8 (7.8 vs 6 2.6% 0.048. 0048 0.048 048 0.048) COVID19. 19. COVID1 COVID- February20 202 0. (CI 42.1 (42.1 57.9 5 (57.9 003 0.03 03 26. 2. 11742 1.17–4.2 20 10737 1.07–3.7 37 3. 1.41–9.8 14198 7.8 (7. 2.6 004 0.04 04 February2 42. (42. 57. (57. 1174 1.17–4. 1073 1.07–3. 1.41–9. 1419 7. (7 (42 (57 117 1.17–4 107 1.07–3 1.41–9 141 ( (4 (5 11 1.17– 10 1.07– 1.41– 14 1.17 1.07 1.41 1.1 1.0 1.4 1.

Resumo Objetivo Avaliar o impacto da raça (negra versus não negra) nos desfechos maternos e perinatais de gestantes com COVID-19 no Brasil. Métodos Esta é uma subanálise da REBRACO, um estudo de coorte multicêntrico brasileiro desenhado para avaliar o impacto da COVID-19 em mulheres grávidas. De fevereiro de 2020 a fevereiro de 2021, 15 maternidades do Brasil coletaram dados de mulheres com sintomas respiratórios. Selecionamos todas as mulheres com teste positivo para COVID-19; em seguida, as dividimos em dois grupos: mulheres negras e não negras. Finalmente, comparamos, entre os grupos, os resultados sociodemográficos, maternos e perinatais. Obtivemos a frequência dos eventos em cada grupo e comparamos usando o teste X2; Valores de p <0,05 foram considerados significativos. Também estimamos o odds ratio (OR) e os intervalos de confiança (IC). Resultados 729 mulheres sintomáticas foram incluídas no estudo; desses, 285 foram positivos para COVID-19, 120 (42,1%) eram negros e 165 (57,9%) não eram negros. As mulheres negras apresentaram pior escolaridade (p = 0,037). O tempo de acesso ao sistema de saúde foi semelhante entre os dois grupos, com 26,3% incluídos com sete ou mais dias de sintomas. Síndrome respiratória aguda grave (OR 2,22 CI 1,17–4,21), admissão em unidade de terapia intensiva (OR 2,00 CI 1,07–3,74) e dessaturação na admissão (OR 3,72 CI 1,41–9,84) foram mais prováveis de ocorrer entre mulheres negras. A mortalidade materna foi maior entre as negras (7,8% vs. 2,6%, p = 0,048). Os resultados perinatais foram semelhantes entre os dois grupos. Conclusão Mulheres negras brasileiras tiveram maior probabilidade de morrer devido às consequências da COVID-19. negra COVID19 COVID 19 COVID-1 REBRACO grávidas 202 2021 1 respiratórios seguida grupos Finalmente sociodemográficos X2 X 005 0 05 <0,0 significativos OR IC. IC . (IC) 72 desses 28 COVID19, 19, 12 42,1% 421 42 (42,1% 16 57,9% 579 57 9 (57,9% 0,037. 0037 0,037 037 0,037) 263 26 3 26,3 222 2 22 2,2 1,17–4,21, 117421 1,17–4,21 , 17 4 21 1,17–4,21) 200 00 2,0 1,07–3,74 107374 07 74 372 3,7 1,41–9,84 141984 41 84 7,8% 78 7 8 (7,8 vs 6 2,6% 0,048. 0048 0,048 048 0,048) COVID19. 19. COVID1 COVID- 20 <0, (IC 42,1 (42,1 57,9 5 (57,9 003 0,03 03 26, 2, 11742 1,17–4,2 1,07–3,7 10737 37 3, 1,41–9,8 14198 7,8 (7, 2,6 004 0,04 04 <0 42, (42, 57, (57, 0,0 1174 1,17–4, 1,07–3, 1073 1,41–9, 1419 7, (7 < (42 (57 0, 117 1,17–4 1,07–3 107 1,41–9 141 ( (4 (5 11 1,17– 1,07– 10 1,41– 14 1,17 1,07 1,41 1,1 1,0 1,4 1,

https://doi.org/10.1055/s-0043-1770133

11.

Radiation safety measures in diagnostic nuclear medicine, based on the potential radiation dose emitted by radioactive patients medicine
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Willegaignon, José

; Fernandes, Samantha Cristina Pereira

; Pelissoni, Rogério Alexandre

; Coura-Filho, George Barbério

; Sapienza, Marcelo Tatit

; Buchpiguel, Carlos Alberto

Radiologia Brasileira

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Fev 2023, Volume 56 Nº 1 Páginas 13 - 20

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

Abstract Objective: To measure the potential radiation dose emitted by patients who have recently undergone diagnostic nuclear medicine procedures, in order to establish optimal radiation safety measures for such procedures. Materials and Methods: We evaluated the radiation doses emitted by 175 adult patients in whom technetium-99m, iodine-131, and fluorine-18 radionuclides were administered for bone, kidney, heart, brain, and whole-body scans, as measured with a radiation detector. Those values served as the basis for evaluating whole-body radiopharmaceutical clearance, as well as the risk for the exposure of others to radiation, depending on the time elapsed since administration of the radiopharmaceutical. Results: The mean time to clearance of the radiopharmaceuticals administered, expressed as the effective half-life, ranged from 1.18 ± 0.30 h to 11.41 ± 0.02 h, and the mean maximum cumulative radiation dose at 1.0 m from the patients was 149.74 ± 56.72 µSv. Even at a distance of 0.5 m, the cumulative dose was found to be only half and one tenth of the limits established for exposure of the general public and family members/caregivers (1.0 mSv and 5.0 mSv per episode, respectively). Conclusion: Cumulative radiation doses emitted by patients immediately after diagnostic nuclear medicine procedures are considerably lower than the limits established by the International Commission on Radiological Protection and the International Atomic Energy Agency, and precautionary measures to avoid radiation exposure are therefore not required after such procedures. Objective Methods 17 technetium99m, technetium99m technetiumm technetium 99m, 99m technetium-99m iodine131, iodine131 iodine 131, 131 iodine-131 fluorine18 fluorine 18 fluorine-1 bone kidney heart brain wholebody whole body scans detector Results halflife, halflife life, life half-life 118 1 1.1 030 0 30 0.3 1141 11 41 11.4 002 02 0.0 10 1. 14974 149 74 149.7 5672 56 72 56.7 µSv 05 5 0. memberscaregivers members caregivers (1. 50 5. episode respectively. respectively . respectively) Conclusion Agency iodine13 13 iodine-13 fluorine1 fluorine- 03 3 114 4 11. 00 1497 14 7 149. 567 56. (1 iodine1 iodine-1 ( iodine-

Resumo Objetivo: O objetivo deste trabalho foi levantar o potencial de dose de radiação emitida por pacientes em procedimentos diagnósticos, visando a estabelecer cuidados de radioproteção mais otimizados. Materiais e Métodos: Taxas de dose de radiação emitidas por 175 pacientes administrados com os radionuclídeos 99mTc, 131I e 18F para cintilografias óssea, renal, cardíaca, cerebral e corpo inteiro, foram mensuradas com um detector de radiação, servindo para avaliar o clareamento do radiofármaco no organismo e risco de exposição após administração dos radiofármacos. Resultados: O clareamento, representado pela meia-vida efetiva, variou de 1,18 ± 0,30 h até 11,41 ± 0,02 h e a dose de radiação máxima acumulada oferecida pelos pacientes a 1,0 m foi de 149,74 ± 56,72 µSv. Mesmo para distâncias de 0,5 m, as doses estimadas foram, respectivamente, duas e dez vezes inferiores ao nível de restrição para o público geral (1,0 mSv) e exposição médica (5,0 mSv/episódio). Conclusão: Doses de radiação oferecidas por pacientes em procedimentos diagnósticos são inferiores aos níveis de restrição recomendados pela International Commission on Radiological Protection e International Atomic Energy Agency, e assim, cuidados de radioproteção são geralmente desnecessários. Objetivo otimizados Métodos 17 99mTc mTc I F óssea renal cardíaca inteiro radiofármacos Resultados meiavida meia vida efetiva 118 1 18 1,1 030 0 30 0,3 1141 11 41 11,4 002 02 0,0 10 1, 14974 149 74 149,7 5672 56 72 56,7 µSv 05 5 0, respectivamente (1, mSv 5,0 50 (5, mSv/episódio. mSvepisódio mSv/episódio . episódio mSv/episódio) Conclusão Agency assim desnecessários 03 3 114 4 11, 00 1497 14 7 149, 567 56, (1 5, (5 (

https://doi.org/10.1590/0100-3984.2022.0064

12.

Modelos teóricos: reflexões necessárias
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de Souza Filho, Breno Augusto Bormann

; Tritany, Érika Fernandes

; Arana, Gustavo Alonso Cabrera

; Struchiner, Cláudio José

Revista Brasileira de Epidemiologia

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2023, Volume 26 elocation e230038

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: Apresentar reflexões teórico-metodológicas sobre elaboraçõo, tipos e funções dos modelos teóricos, bem como suas estruturas conceituais e de análise. Métodos: Trata-se de um ensaio cujo processo de coleta do material foi realizado de forma não sistemática, eleito exclusivamente e baseado na linha de argumentaçõo e reflexão que os autores pretendem submeter à apreciaçõo e ao debate público. Resultados: Este trabalho apresenta reflexões sobre tipos e funções dos modelos teóricos, fundamentaçõo teórica nas pesquisas e reflexões sobre a importância dos modelos teóricos para as pesquisas em saúde pública e sua relaçõo com o processo de elaboraçõo, desenvolvimento e relato nos estudos científicos. Além disso, são descritos tipos de modelos teóricos referentes aos planos conceitual e empírico, e a importante elaboraçõo e descriçõo da junçõo de ambos para o fazer científico. Conclusão: Espera-se que este artigo levante discussões e reflexões sobre os métodos atuais que permeiam o fazer científico e fomentem a utilizaçõo dos modelos teóricos como base das pesquisas científicas em seu processo de elaboraçõo, desenvolvimento e relato.

ABSTRACT Objective: To present theoretical-methodological reflections on the elaboration, types, and functions of theoretical models as well as their conceptual and analytic frameworks. Methods: This is an essay, whose material collection was carried out in a non-systematic way, by electing studies exclusively based on the line of argument and reflection that the authors intend to submit to appreciation and public debate. Results: We present reflections on the types and functions of theoretical models, theoretical foundations in research, and reflections on the importance of theoretical models for public health research and their relation with the process of elaboration, development, and reporting in scientific studies. In addition, we describe types of theoretical models referring to the conceptual and empirical levels and the important elaboration and description of their combination for scientific practice. Conclusion: With this article, our intention is to stimulate discussions and reflections on current methods that permeate scientific practice and encourage the use of Theoretical Models as a basis for scientific research in its elaboration, development, and reporting process.

https://doi.org/10.1590/1980-549720230038.2

13.

Morpho-physiological and anatomical characteristics of Urochloa brizantha cv. Marandu in silvopastoral and monoculture systems Morphophysiological Morpho physiological cv
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Sousa, Luciano Fernandes

; Moreira, Guilherme Rocha

; Lemos Filho, José Pires de

; Paciullo, Domingos Savio Campos

; Vendramini, João Maurício Bueno

; Luna, Robert Emilio Mora

; Maurício, Rogério Martins

Acta Scientiarum. Animal Sciences

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2023, Volume 45 elocation e59494

Resumo: En | Texto: En | PDF: En

ABSTRACT. To gain insights into the forage morphological and anatomical characteristics in a silvopastoral system (SPS) with Bolsa de Pastor (Zeyheria tuberculosa) and palisadegrass ‘Marandu’ (Urochloa brizantha) monoculture (MONO). The SPS was established through natural regeneration of the tree species. Treatments were a SPS and MONO distributed in a completely randomized design with six replicates and repeated measures were the harvest periods. Response variables were morpho-physiological and anatomical characteristicss: green: dead material ratio, leaf blade: stem+sheath ratio, leaf area index, chlorophyll and carotenoid concentrations, proportions of non-lignified and achlorophyllous areas, lignified areas in stems, proportions of non-lignified and achlorophyllous areas, lignified and chlorophyllous areas in leaves, as well as cell length in longitudinal section of stem. Morpho-physiological patterns were altered (p < 0.05) under natural shading conditions due to higher photosynthetic efficiency in the SPS. There was no effect (p > 0.05) of the systems on anatomical patterns, proportions of non-lignified and achlorophyllous, lignified and chlorophyllous tissues, these proportions were influenced only by the periods of the year, both for stems and leaves. Cells of the internodes of the grasses of the studied systems had the same length. The SPS alters morpho-physiological characteristics of palisadegrass and increases the concentration of chlorophyll a and b. ABSTRACT (SPS Zeyheria tuberculosa ‘Marandu Marandu Urochloa brizantha MONO. . (MONO) species morphophysiological morpho physiological characteristicss green ratio blade stemsheath stem sheath index concentrations nonlignified non leaves Morphophysiological Morpho p 0.05 005 0 05 tissues year b (MONO 0.0 00 0.

https://doi.org/10.4025/actascianimsci.v45i1.59494

14.

Modelos teóricos: reflexões necessárias teóricos
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de Souza Filho, Breno Augusto Bormann

; Tritany, Érika Fernandes

; Arana, Gustavo Alonso Cabrera

; Struchiner, Cláudio José

Revista Brasileira de Epidemiologia

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2023, Volume 26 elocation e230038

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

https://doi.org/10.1590/1980-549720230038.2

15.

Perspectivas de pacientes sobre a vivência da psoríase: um estudo qualitativo com base na teoria Junguiana psoríase
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Vieira, Camila Martins

; Vanderlei, Lygia Carmen de Moraes

; Barbosa, Leopoldo Nelson Fernandes

; Nascimento, Ananda Kenney da Cunha

; Dias, Mirian Rique de Souza Brito

; Cabral Filho, José Eulálio

Psicologia: Teoria e Pesquisa

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2023, Volume 39 elocation e39406

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

ABSTRACT Psoriasis is an inflammatory and chronic skin disease, of a benign, systemic, immune-mediated and non-contagious nature. It was intended to understand the symbolic expressions of psoriasis and its repercussions on the process of individuation of adult patients through qualitative descriptive-interpretative research. Open interview, thematic content analysis technique and theoretical framework of Analytical Psychology were used. Sample of sixteen participants with psoriasis in outpatient treatment. The categories outlined: psoriasis as a symbol: onset, crises and remission; treatment routine: from the skin frontier to the inner world; and, himself: a path of approaches and distances. The development of the adult with psoriasis was understood by the symbolic experiences that pointed to changes in integral health. However, it was recognized that the relations between psyche and body, although conflicting, provided learning and favored the individuation process. disease benign systemic immunemediated immune mediated noncontagious non contagious nature descriptiveinterpretative descriptive interpretative research interview used outlined symbol onset remission routine world himself distances health However body conflicting

RESUMO A psoríase é uma doença inflamatória e crônica de pele, de natureza benigna, sistêmica, imunomediada e não contagiosa. Pretendeu-se compreender as expressões simbólicas da psoríase e suas repercussões no processo de individuação de pacientes adultos por meio de uma pesquisa qualitativa descritivo-interpretativa. Utilizada entrevista aberta, técnica de análise de conteúdo temática e referencial teórico da Psicologia Analítica. Amostra de dezesseis participantes com psoríase em tratamento ambulatorial. Delineadas as categorias: psoríase como símbolo: surgimento, crises e remissão; rotina de tratamento: da fronteira da pele ao mundo interior; e, si-mesmo: vereda de aproximações e afastamentos. O desenvolvimento do adulto com psoríase foi compreendido pelas vivências simbólicas que apontaram para alterações na saúde integral. No entanto, reconheceu-se que as relações entre psique e corpo, apesar de conflituosas, proporcionaram aprendizados e favoreceram o processo de individuação. benigna sistêmica contagiosa Pretendeuse Pretendeu se descritivointerpretativa. descritivointerpretativa descritivo interpretativa. interpretativa descritivo-interpretativa aberta Analítica ambulatorial categorias símbolo surgimento remissão interior simesmo si mesmo si-mesmo afastamentos integral entanto reconheceuse reconheceu corpo conflituosas

https://doi.org/10.1590/0102.3772e39406.pt

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