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Low oral health literacy, dental caries, and school features are associated with reasons for seeking dental services among adolescents
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Lopes, Roanny Torres

; Neves, Érick Tássio Barbosa

; Dutra, Laio da Costa

; Firmino, Ramon Targino

; Lima, Larissa Chaves Morais de

; Ferreira, Fernanda de Morais

; Granville-Garcia, Ana Flávia

Revista Brasileira de Epidemiologia

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2024, Volume 27 elocation e2400466

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/1980-549720240066

Leishmania (Sauroleishmania) tarentolae versus pathogenic species: comparative evaluation of protease activity, glycoconjugates, resistance to complement and metabolome composition Sauroleishmania (Sauroleishmania species activity glycoconjugates
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Andrade, Filipe Fideles Duarte

; Vitório, Jéssica Gardone

; Canuto, Gisele André Baptista Nunes, Fernanda Freire Campos Rodrigues, Isabela Aurora Almeida, Ana Paula Martins Morais Nascimento, Frederico Crepaldi Costa, Adriana Oliveira Vieira, Tamara da Silva Silva, Ana Carolina Carvalho André, Leiliane Coelho Gontijo, Célia Maria Ferreira Junqueira, Caroline Toledo, Juliano Simões de Fernandes, Ana Paula Soares, Rodrigo Pedro

Memórias do Instituto Oswaldo Cruz

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2024, Volume 119 elocation e230243

Resumo: En | Texto: En | PDF: En

BACKGROUND Leishmania tarentolae is a non-pathogenic species found in lizards representing an important model for Leishmania biology. However, several aspects of this Sauroleishmania remain unknown to explain its low level of virulence. OBJECTIVES We reported several aspects of L. tarentolae biology including glycoconjugates, proteolytic activities and metabolome composition in comparison to pathogenic species (Leishmania amazonensis, Leishmania braziliensis, Leishmania infantum and Leishmania major). METHODS Parasites were cultured for extraction and purification of lipophosphoglycan (LPG), immunofluorescence probing with anti-gp63 and resistance against complement. Parasite extracts were also tested for proteases activity and metabolome composition. FINDINGS Leishmania tarentolae does not express LPG on its surface. It expresses gp63 at lower levels compared to pathogenic species and, is highly sensitive to complement-mediated lysis. This species also lacks intracellular/extracellular activities of proteolytic enzymes. It has metabolic differences with pathogenic species, exhibiting a lower abundance of metabolites including ABC transporters, biosynthesis of unsaturated fatty acids and steroids, TCA cycle, glycine/serine/threonine metabolism, glyoxylate/dicarboxylate metabolism and pentose-phosphate pathways. MAIN CONCLUSIONS The non-pathogenic phenotype of L. tarentolae is associated with alterations in several biochemical and molecular features. This reinforces the need of comparative studies between pathogenic and non-pathogenic species to elucidate the molecular mechanisms of virulence during host-parasite interactions. nonpathogenic non However L glycoconjugates amazonensis braziliensis major. major . major) LPG, , (LPG) antigp63 antigp anti gp anti-gp6 complement surface gp6 complementmediated mediated lysis intracellularextracellular intracellular extracellular enzymes transporters steroids cycle glycineserinethreonine glycine serine threonine glyoxylatedicarboxylate glyoxylate dicarboxylate pentosephosphate pentose phosphate pathways features hostparasite host parasite interactions (LPG antigp6 anti-gp

https://doi.org/10.1590/0074-02760230243

Cross-cultural adaptation of the eHealth Literacy Scale for Brazilian adolescents Crosscultural Cross cultural
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BARBOSA, Mariane Carolina Faria

; BALDIOTTI, Ana Luiza Peres

; DIAS, Maria Luisa Leandro de Souza

; GRANVILLE-GARCIA, Ana Flávia

; PAIVA, Saul Martins

; FERREIRA, Fernanda de Morais

Brazilian Oral Research

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2024, Volume 38 elocation e094

Resumo: En | Texto: En | PDF: En

ABSTRACT The aim of this study was to undertake a cross-cultural adaptation of the eHealth Literacy Scale (eHEALS) instrument to measure digital health literacy of Brazilian adolescents. eHEALS is a scale consisting of 8 items that measure self-perception related to the consumption of electronic health information. This is a methodological study of cross-cultural adaptation, conducted out from February 2022 to June 2022. The following steps were carried out: a) assessment and adequacy of cultural equivalence by a committee of experts; b) back-translation; c) synthesis of back-translations; d) cognitive testing with 42 Brazilian adolescents, using cognitive interviews with probing questions. All items that were difficult to understand were adapted to the (language) context of Brazilian adolescents. Cronbach’s alpha coefficient for eHEALS-BrA was 0.81 and, if one of the items were excluded from the instrument, it ranged from 0.75-0.81. This version of the eHEALS proved to be culturally well-adapted to the context of Brazilian adolescents, and has the potential to measure digital health literacy in this population after having its validation confirmed through psychometric analyses. crosscultural cross (eHEALS adolescents selfperception self perception information 202 experts b backtranslation back translation back-translation c backtranslations translations back-translations d 4 questions language (language Cronbachs Cronbach s eHEALSBrA BrA 081 0 81 0.8 0.750.81. 075081 0.75 0.81. 75 0.75-0.81 welladapted well analyses 20 08 0. 750 0.750.81 07508 075 0.7 7 0.75-0.8 2 0.750.8 0750 07 0.75-0. 0.750. 0.75-0 0.750 0.75-

https://doi.org/10.1590/1807-3107bor-2024.vol38.0094

Low oral health literacy, dental caries, and school features are associated with reasons for seeking dental services among adolescents literacy caries
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Lopes, Roanny Torres

; Neves, Érick Tássio Barbosa

; Dutra, Laio da Costa

; Firmino, Ramon Targino

; Lima, Larissa Chaves Morais de

; Ferreira, Fernanda de Morais

; Granville-Garcia, Ana Flávia

Revista Brasileira de Epidemiologia

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2024, Volume 27 elocation e2400466

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: O presente estudo teve como objetivo investigar associações entre os motivos da busca por serviços odontológicos, considerando a última consulta odontológica de adolescentes, e suas características escolares, status socioeconômico e bucal e alfabetização em saúde bucal. Métodos: Foi realizado um estudo transversal com 746 adolescentes de 15–19 anos em Campina Grande (Paraíba), Brasil. Os pais/responsáveis responderam a um questionário socioeconômico. Os adolescentes responderam a um questionário de saúde bucal e à versão brasileira do Rapid Estimate of Adult Literacy in Dentistry (rápida estimativa de alfabetização de adultos em odontologia). As características do contexto escolar foram investigadas por meio de análise de cluster, utilizando tipo de escola e taxa de retenção escolar. Os adolescentes foram examinados clinicamente para diagnóstico de cárie dentária por dois dentistas (κ>0,80), usando os critérios de Nyvad, nas instalações das escolas. Os dados foram submetidos à regressão logística multinível robusta para amostras complexas (α=5%). Resultados: No nível individual, a baixa escolaridade da mãe (razão de probabilidade [OR] 1,06; IC95% 1,01–1,10), alfabetização em saúde bucal inferior (OR 0,99; IC95% 0,98–0,99) e cárie dentária (OR 1,09; IC95% 1,01–1,18) permaneceram associados ao motivo da última consulta odontológica. O ambiente escolar também foi associado ao desfecho (OR 1,07; IC95% 1,00–1,15). Conclusão: Escolaridade materna com menos de oito anos de estudo, baixa literacia em saúde bucal, cárie cavitada e ambiente escolar desfavorável foram associados à procura por tratamento odontológico. Objetivo odontológicos escolares Métodos 74 1519 15 19 15–1 Paraíba, Paraíba , (Paraíba) Brasil paisresponsáveis pais responsáveis rápida odontologia. odontologia . odontologia) cluster κ>0,80, κ080 κ κ>0,80 0 80 (κ>0,80) Nyvad escolas α=5%. α5 α α=5% 5 (α=5%) Resultados individual razão OR [OR 1,06 106 1 06 IC95 IC 1,01–1,10, 101110 1,01–1,10 01 10 1,01–1,10) 0,99 099 99 0,98–0,99 098099 98 1,09 109 09 1,01–1,18 101118 18 1,07 107 07 1,00–1,15. 100115 1,00–1,15 00 1,00–1,15) Conclusão odontológico 7 151 15– (Paraíba κ08 κ>0,8 8 (κ>0,80 α=5 (α=5% 1,0 IC9 10111 1,01–1,1 0,9 9 0,98–0,9 09809 10011 1,00–1,1 κ0 κ>0, (κ>0,8 α= (α=5 1, 1011 1,01–1, 0, 0,98–0, 0980 1001 1,00–1, κ>0 (κ>0, (α= 101 1,01–1 0,98–0 098 100 1,00–1 κ> (κ>0 (α 1,01– 0,98– 1,00– (κ> 1,01 0,98 1,00 (κ

ABSTRACT Objective: The present study aimed to investigate associations between reasons for seeking dental services, considering the last dental appointment of adolescents, and their educational features, socioeconomic and oral health status, and oral health literacy. Methods: A cross-sectional study was conducted with 746 adolescents aged 15–19 years in Campina Grande (Paraíba), Brazil. Parents/guardians answered a socioeconomic questionnaire. Adolescents answered a questionnaire on oral health and the Brazilian Rapid Estimate of Adult Literacy in Dentistry. Features of the school environment were investigated through cluster analysis, using type of school and school grade retention. Adolescents were clinically examined for dental caries diagnosis by two dentists (κ>0.80), using the Nyvad criteria, in school facilities. Data were submitted to robust multilevel logistic regression for complex samples (α=5%). Results: At the individual level, low maternal schooling (odds ratio [OR] 1.06; 95%CI 1.01–1.10), low oral health literacy (OR 0.99; 95%CI 0.98–0.99), and dental caries (OR 1.09; 95%CI 1.01-1.18) remained associated with the reasons for the last dental appointment. The school environment was also associated with the outcome (OR 1.07; 95%CI 1.00–1.15). Conclusion: Maternal schooling of less than eight years of study, low oral health literacy, cavitated caries, and unfavorable school environment were associated with seeking dental treatment. Objective services features status Methods crosssectional cross sectional 74 1519 15 19 15–1 Paraíba, Paraíba , (Paraíba) Brazil Parentsguardians Parents guardians Dentistry analysis retention κ>0.80, κ080 κ κ>0.80 0 80 (κ>0.80) criteria facilities α=5%. α5 α α=5% . 5 (α=5%) Results level odds OR [OR 1.06 106 1 06 95CI CI 95 1.01–1.10, 101110 1.01–1.10 01 10 1.01–1.10) 0.99 099 99 0.98–0.99, 098099 0.98–0.99 98 0.98–0.99) 1.09 109 09 1.011.18 101118 1.01 1.18 18 1.01-1.18 1.07 107 07 1.00–1.15. 100115 1.00–1.15 00 1.00–1.15) Conclusion treatment 7 151 15– (Paraíba κ08 κ>0.8 8 (κ>0.80 α=5 (α=5% 1.0 9 10111 1.01–1.1 0.9 09809 0.98–0.9 011 1.011.1 101 118 1.1 1.01-1.1 10011 1.00–1.1 κ0 κ>0. (κ>0.8 α= (α=5 1. 1011 1.01–1. 0. 0980 0.98–0. 1.011. 11 1.01-1. 1001 1.00–1. κ>0 (κ>0. (α= 1.01–1 098 0.98–0 1.011 1.01-1 100 1.00–1 κ> (κ>0 (α 1.01– 0.98– 1.01- 1.00– (κ> 0.98 1.00 (κ

https://doi.org/10.1590/1980-549720240066

Seasonality of chrysanthemum commercialization in the west region of São Paulo: the case of breeder
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Franco, Lucas Morais Nahass

; Vendruscolo, Eduardo Pradi

; Bastos, Fernanda Espíndola Assumpção

; Cunha, Pamela Stephany Jennings

; Martins, Murilo Battistuzzi

; Vetruve, Ítalo Ferreira

Ornamental Horticulture

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Out 2023, Volume 29 Nº 4 Páginas 430 - 437

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

Abstract The Flowers and Ornamental Plant sector supports an extensive network of entrepreneurs, in all stages related to cultivation, transport and commercialization. In this aspect, there is a great demand for skilled labor, making this sector a source of employment and income generation in the regions covered. However, there is great interference on the commercialization of flowers and ornamental plants by the seasonality of demand, which is often related to festive dates, weather, among other factors. Thus, knowledge about seasonal demands allows the sector to develop a plan, directing efforts to offer products with greater demand in a given period. This study aimed to generate information, through a case study based on the analysis of commercialization data, and verify the seasonal demand on the commercialization of ornamental species in western São Paulo. There was an increase in the demand for chrysanthemum cuttings, both for the domestic and export markets, during the years 2019 and 2020, in addition to fluctuations in the demand for some cultivars of cuttings of chrysanthemum in one year compared to the other. Through the analysis, it is concluded that the seasonality of commercialization of ornamental plants in the West Region of São Paulo really occurs, especially between the 26th and 34th week of the year, with the purpose of serving the domestic market of chrysanthemums. This result allows planning the planting and harvesting time, as well as the definition of the best varieties to be cultivated in these periods.

Resumo O setor de Flores e Plantas Ornamentais apoia uma extensa rede de empreendedores, em todas as etapas relacionadas ao cultivo, transporte e comercialização. Neste aspecto, há uma grande demanda por mão-de-obra qualificada, tornando este setor fonte de emprego e geração de renda nas regiões abrangidas. Porém, há grande interferência na comercialização de flores e plantas ornamentais pela sazonalidade da demanda, que muitas vezes está relacionada a datas festivas, clima, entre outros fatores. Assim, o conhecimento sobre as demandas sazonais permite ao setor desenvolver um planejamento, direcionando esforços para oferecer produtos com maior demanda em determinado período. Este estudo teve como objetivo gerar informações, por meio de um estudo de caso baseado na análise de dados de comercialização, e verificar a demanda sazonal na comercialização de espécies ornamentais no oeste paulista. Houve aumento na demanda por mudas de crisântemo, tanto para o mercado interno quanto para exportação, durante os anos de 2019 e 2020, além de oscilações na demanda por algumas cultivares de mudas de crisântemo em um ano em relação ao outro. Através desta análise conclui-se que a sazonalidade da comercialização de plantas ornamentais na Região Oeste de São Paulo realmente ocorre, principalmente entre a 26ª e a 34ª semana do ano, com a finalidade de atender ao mercado interno de crisântemos. Este resultado permite planejar a época de plantio e colheita, bem como a definição das melhores variedades a serem cultivadas nestes períodos.

https://doi.org/10.1590/2447-536x.v29i4.2585

Cross-cultural adaptation of the Digital Health Literacy Instrument (DHLI) for use on Brazilian adolescents Crosscultural Cross cultural DHLI (DHLI
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Barbosa, Mariane Carolina Faria

; Baldiotti, Ana Luiza Peres

; Braga, Náyra Santos

; Lopes, Camila Takáo

; Paiva, Saul Martins

; Granville-Garcia, Ana Flávia

; Ferreira, Fernanda de Morais

Brazilian Dental Journal

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Out 2023, Volume 34 Nº 5 Páginas 104 - 114

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo O estudo teve o objetivo de adaptar transculturalmente o Digital Health Literacy Instrument (DHLI) para adolescentes nativos do idioma português do Brasil (DHLI-BrA). O estudo de adaptação transcultural consistiu nas seguintes etapas: tradução, avaliação e adequação de equivalência cultural da tradução por comitê de especialistas; retrotradução e síntese das retrotraduções. Foi realizada a testagem cognitiva em pré-teste com adolescentes, utilizando-se entrevistas cognitivas com perguntas de sondagem sobre a compreensão e interpretação dos itens e opções de resposta. O alfa de Cronbach e ômega de McDonald’s foram utilizados para estimar a confiabilidade do instrumento. Participaram do pré-teste 42 adolescentes brasileiros com média de idade de 16,0 ± 2,0 (variação de 13-19) anos. Os itens com dificuldade de compreensão foram adaptados ao contexto dos adolescentes brasileiros. O coeficiente alfa de Cronbach e o ômega de McDonald’s, para os 21 itens do DHLI-BrA foi respectivamente, 0,79 e 0,80. O coeficiente alfa de Cronbach para as subescalas do instrumento de autorrelato foi de 0,53-0,79 (variação), demonstrando boa confiabilidade no instrumento total e confiabilidade moderada nas subescalas. Este estudo fornece a versão adaptada transculturalmente do Digital Health Literacy Instrument (DHLI), um instrumento de mensuração do letramento digital em saúde, para utilização em adolescentes brasileiros (DHLI-BrA). DHLI (DHLI DHLIBrA. DHLIBrA BrA . (DHLI-BrA) etapas especialistas retrotraduções préteste pré teste utilizandose utilizando se resposta McDonalds McDonald s 4 160 16 0 16, 20 2 2, variação 1319 13 19 13-19 anos McDonalds, s, respectivamente 079 79 0,7 080 80 0,80 0,530,79 053079 0,53 53 0,53-0,7 variação, , (variação) DHLI, saúde (DHLI-BrA 1 131 13-1 07 7 0, 08 8 0,8 530 0,530,7 05307 053 0,5 5 0,53-0, 13- 0,530, 0530 05 0,53-0 0,530 0,53-

Abstract The present study aimed to perform the cross-cultural adaptation of the Digital Health Literacy Instrument (DHLI) for native Brazilian Portuguese-speaking adolescents (DHLI-BrA). Cross-cultural adaptation consisted of the following steps: translation, assessment, and adjustments by the expert committee to ensure cultural equivalence; back-translation, and synthesis of back-translations. Cognitive testing was then performed in a pretest with adolescents using cognitive interviews with probing questions on the item's understanding interpretation and response options. Cronbach’s alpha coefficient and McDonald’s omega were used to estimate the instrument’s reliability. Forty-two Brazilian adolescents participated in the study (mean age: 16.0 ± 2.0 years; range: 13 to 19 years). Items that were difficult to understand were adapted to the context of Brazilian adolescents. Cronbach’s alpha coefficient and McDonald’s omega for the 21 items of the DHLI-BrA were, respectively, 0.79 and 0.80. Cronbach’s alpha coefficient for the subscales of the self-report instrument was 0.53-0.79 (range), demonstrating good reliability in the total instrument and moderate reliability in the subscales. This study provides the cross-cultural adapted version of the Digital Health Literacy Instrument (DHLI), which is an instrument for measuring digital Health literacy, for use in Brazilian adolescents (DHLI-BrA). crosscultural cross DHLI (DHLI Portuguesespeaking Portuguese speaking DHLIBrA. DHLIBrA BrA . (DHLI-BrA) Crosscultural Cross steps translation assessment equivalence backtranslation, backtranslation back back-translation backtranslations. backtranslations translations. translations back-translations item s options Cronbachs Cronbach McDonalds McDonald instruments Fortytwo Forty two mean age 160 16 0 16. 20 2 2. years range 1 years. years) respectively 079 79 0.7 080 80 0.80 selfreport self report 0.530.79 053079 0.53 53 0.53-0.7 range, , (range) DHLI, literacy (DHLI-BrA 07 7 0. 08 8 0.8 530 0.530.7 05307 053 0.5 5 0.53-0. (range 0.530. 0530 05 0.53-0 0.530 0.53-

https://doi.org/10.1590/0103-6440202305346

Seeking treatment for traumatic dental injuries in schoolchildren: A multilevel analysis schoolchildren
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Bernardino, Veruska Medeiros Martins

; Lima, Larissa Chaves Morais de

; Araújo, Luiza Jordânia Serafim de

; Neves, Érick Tássio Barbosa

; Ferreira, Fernanda de Morais

; Granville-Garcia, Ana Flávia

Brazilian Dental Journal

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Out 2023, Volume 34 Nº 5 Páginas 95 - 103

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo Investigar fatores individuais e contextuais associados à busca de tratamento para lesões dentárias traumáticas. Foi realizado um estudo transversal com 739 pares de responsáveis e crianças. Os responsáveis responderam a um questionário abordando características sociodemográficas, busca por tratamento para traumatismo dentário na criança e o Questionário de alfabetização em saúde bucal para adulto. Análise descritiva e análise de regressão de Poisson multinível não ajustada e ajustada (p<0,05) foram realizadas. A prevalência de busca de tratamento para lesão dentária traumática foi de 44,7%. As variáveis sociodemográficas associadas foram a pele branca da criança (RP = 1,30; IC 95%: 1,08-1,76), idade da mãe maior que 35 anos (RP = 1,70; IC 95%: 1,50-1,90), os responsáveis casados (RP = 1,93; IC 95%: 1,70-2,23), com mais de oito anos de estudo (RP = 2,00; IC 95%: 1,76-2,23), com alfabetização adequada em saúde bucal (RP = 2,00; IC 95%: 1,76-2,23) e uso diário de dispositivos eletrônicos pela criança (RP = 1,26; IC 95%: 1,02-1,50). No nível contextual, frequentar uma escola particular (PR = 1,77; IC 95%: 1,02-3,05) e a quantidade de unidades básicas de saúde com equipes de saúde bucal no distrito sanitário da escola (PR = 1,78; IC 95%: 1,12-2,38) permaneceram associados. Entre as crianças que sofreram TDI, a alfabetização em saúde bucal adequada dos pais foi um fator que se destacou na busca por tratamento. traumáticas 73 adulto p<0,05 p005 p 0 05 (p<0,05 realizadas 447 44 7 44,7% RP 1,30 130 1 30 95% 95 1,081,76, 108176 1,08 1,76 , 08 76 1,08-1,76) 3 1,70 170 70 1,501,90, 150190 1,50 1,90 50 90 1,50-1,90) 1,93 193 93 1,702,23, 170223 2,23 2 23 1,70-2,23) 2,00 200 00 1,762,23, 176223 1,762,23 1,76-2,23 1,26 126 26 1,021,50. 102150 1,02 . 02 1,02-1,50) contextual PR 1,77 177 77 1,023,05 102305 3,05 1,02-3,05 1,78 178 78 1,122,38 112238 1,12 2,38 12 38 1,12-2,38 TDI p<0,0 p00 (p<0,0 4 44,7 1,3 13 9 081 1,081,76 10817 108 1,0 176 1,7 1,08-1,76 17 501 1,501,90 15019 150 1,5 190 1,9 5 1,50-1,90 19 702 1,702,23 17022 223 2,2 1,70-2,23 2,0 20 762 17622 1,762,2 1,76-2,2 1,2 021 1,021,50 10215 102 1,02-1,50 023 1,023,0 10230 305 3,0 1,02-3,0 122 1,122,3 11223 112 1,1 238 2,3 1,12-2,3 p<0, p0 (p<0, 44, 1, 1,081,7 1081 10 1,08-1,7 1,501,9 1501 15 1,50-1,9 1,702,2 1702 22 2, 1,70-2,2 1762 1,762, 1,76-2, 1,021,5 1021 1,02-1,5 1,023, 1023 3, 1,02-3, 1,122, 1122 11 1,12-2, p<0 (p<0 1,081, 1,08-1, 1,501, 1,50-1, 1,702, 1,70-2, 1,762 1,76-2 1,021, 1,02-1, 1,023 1,02-3 1,122 1,12-2 p< (p< 1,081 1,08-1 1,501 1,50-1 1,702 1,70-2 1,76- 1,021 1,02-1 1,02- 1,12- (p 1,08- 1,50- 1,70-

ABSTRACT To investigate individual and contextual factors associated with seeking treatment for traumatic dental injuries. A cross-sectional study was conducted with 739 pairs of guardians and children. Guardians answered a questionnaire addressing sociodemographic characteristics, seeking treatment for a tooth injury in the child, and the Oral Health Literacy-Adult Questionnaire. Descriptive analysis and unadjusted and adjusted multilevel Poisson regression analysis (p<0.05). The prevalence of seeking treatment for traumatic dental injury was 44.7%. Sociodemographic variables associated were white skin of the child (PR = 1.30; 95% CI: 1.08-1.76), mother’s age older than 35 years (PR = 1.70; 95% CI: 1.50-1.90), married parents (PR = 1.93; 95% CI: 1.70-2.23), guardians with more than eight years of schooling (PR = 2.00; 95% CI: 1.76-2.23), with adequate oral health literacy (PR = 3.33; 95% CI: 3.01-3.62) and the daily use of electronic devices by the child (PR = 1.26; 95% CI: 1.02-1.50). On the contextual level, attending a private school (PR = 1.77; 95% CI: 1.02-3.05) and the number of primary care units with oral health teams in the school district (PR = 1.78; 95% CI: 1.12-2.38) remained associated. Among the children who suffered TDI, adequate oral health literacy on the part of the parents stood out among the factors associated with seeking treatment. injuries crosssectional cross sectional 73 characteristics LiteracyAdult Literacy Adult Questionnaire p<0.05. p005 p p<0.05 . 0 05 (p<0.05) 447 44 7 44.7% PR 1.30 130 1 30 95 CI 1.081.76, 108176 1.08 1.76 , 08 76 1.08-1.76) mothers mother s 3 1.70 170 70 1.501.90, 150190 1.50 1.90 50 90 1.50-1.90) 1.93 193 93 1.702.23, 170223 2.23 2 23 1.70-2.23) 2.00 200 00 1.762.23, 176223 1.76-2.23) 3.33 333 33 3.013.62 301362 3.01 3.62 01 62 3.01-3.62 1.26 126 26 1.021.50. 102150 1.02 02 1.02-1.50) level 1.77 177 77 1.023.05 102305 3.05 1.02-3.05 1.78 178 78 1.122.38 112238 1.12 2.38 12 38 1.12-2.38 TDI p00 p<0.0 (p<0.05 4 44.7 1.3 13 9 081 1.081.76 10817 108 1.0 176 1.7 1.08-1.76 17 501 1.501.90 15019 150 1.5 190 1.9 5 1.50-1.90 19 702 1.702.23 17022 223 2.2 1.70-2.23 2.0 20 762 1.762.23 17622 1.76-2.23 3.3 013 3.013.6 30136 301 3.0 362 3.6 6 3.01-3.6 1.2 021 1.021.50 10215 102 1.02-1.50 023 1.023.0 10230 305 1.02-3.0 122 1.122.3 11223 112 1.1 238 2.3 1.12-2.3 p0 p<0. (p<0.0 44. 1. 1.081.7 1081 10 1.08-1.7 1.501.9 1501 15 1.50-1.9 1.702.2 1702 22 2. 1.70-2.2 1.762.2 1762 1.76-2.2 3. 3.013. 3013 36 3.01-3. 1.021.5 1021 1.02-1.5 1.023. 1023 1.02-3. 1.122. 1122 11 1.12-2. p<0 (p<0. 1.081. 1.08-1. 1.501. 1.50-1. 1.702. 1.70-2. 1.762. 1.76-2. 3.013 3.01-3 1.021. 1.02-1. 1.023 1.02-3 1.122 1.12-2 p< (p<0 1.081 1.08-1 1.501 1.50-1 1.702 1.70-2 1.762 1.76-2 3.01- 1.021 1.02-1 1.02- 1.12- (p< 1.08- 1.50- 1.70- 1.76- (p

https://doi.org/10.1590/0103-6440202305555

Parental oral health literacy influences preschool children's utilization of dental services
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Menoncin, Bruna Leticia Vessoni

; Crema, Aline Fabris de Araujo

; Ferreira, Fernanda de Morais

; Zandoná, Andrea Ferreira

; Menezes, Jose Vitor Nogara Borges de

; Fraiz, Fabian Calixto

Brazilian Oral Research

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2023, Volume 37 elocation e090

Resumo: En | Texto: En | PDF: En

Abstract: Parental behavior towards their children's oral health is strongly influenced by parent's Oral Health Literacy (OHL) level. This study evaluated the impact of parental OHL on preschool children's utilization of dental services. A cross-sectional study was conducted with parents of 419 children aged 3 to 5 years who answered a self-administered questionnaire about their perception of their children's oral health and whether their children had already been to a dental visit. Parental OHL level was assessed by the validated version of the Oral Health Literacy Adult Questionnaire (OHL-AQ) translated into Brazilian Portuguese. Univariate and multivariate Poisson regression analyses with robust variance were used for the data analysis (α = 0.05). Most children had already been to a dental visit (73%). Overall, 31.7% of the parents or guardians reported that their children had experienced dental pain or dental caries. Parental OHL level was classified by tercile as low, medium, and high. The final model showed independent associations between children who had already been to a dental visit and higher parental OHL level (PR = 1.16; 95%CI = 1.00-1.35) when compared to the lowest OHL level, higher parental educational level (PR = 1.39; 95%CI = 1.03–1.87) when compared to lower educational level, the report of children's pain and dental caries (PR = 1.22; 95%CI = 1.09–1.36) and married parents or parents in a common-law marriage (PR = 1.17; 95%CI = 1.03–1.93). The prevalence of children who had already been to a dental visit was higher among those parents with a higher OHL level when compared to those with a lower OHL level.

https://doi.org/10.1590/1807-3107bor-2023.vol37.0090

Predictors associated with malocclusion in children with and without sleep disorders: a cross-sectional study
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GRANJA, Gélica Lima

; LEAL, Tiago Ribeiro

; LIMA, Larissa Chaves Morais de

; SILVA, Samara Ellen da

; NEVES, Érick Tássio Barbosa

; FERREIRA, Fernanda Morais

; GRANVILLE-GARCIA, Ana Flávia

Brazilian Oral Research

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2023, Volume 37 elocation e106

Resumo: En | Texto: En | PDF: En

Abstract The aim of the present study was to investigate predictors of malocclusion in Brazilian schoolchildren eight to ten years of age based on a causal directed acyclic graph model. A cross-sectional study was conducted with 739 schoolchildren eight to ten years of age. Parents/guardians provided information on sleep disorders of the child (Sleep Disturbance Scale for Children) and family characteristics (Family Adaptability and Cohesion Evaluation Scale). The diagnosis of malocclusion was performed by four trained examiners using the Dental Aesthetic Index. Control variables were selected using a directed acyclic graph. Descriptive analysis was performed, followed by robust logistic regression analysis for complex samples (α = 5%). The following variables were associated with malocclusion in the final model: sleep disorders (OR = 2.61; 95%CI: 2.43–2.86), mouth breathing (OR = 1.04; 95%CI: 1.02–1.99), non-nutritive sucking habits (OR = 2.45; 95%CI: 2.37–4.85), and obesity (OR = 1.54; 95%CI: 1.02–2.33). Sociodemographic characteristics, family functioning, and premature tooth loss did not remain associated with malocclusion. Sleep disorders, mouth breathing, sucking habits, and obesity are predictors of malocclusion in schoolchildren eight to ten years of age.

https://doi.org/10.1590/1807-3107bor-2023.vol37.0106

10.

FATORES RELACIONADOS À SOBRECARGA E AO AUTOCUIDADO PARA HIPERTENSÃO EM CUIDADORES FAMILIARES
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Lima, Talita Morais Ferreira

; Costa, Andréa Fachini da

; Lopes, Maria Carolina Barbosa Teixeira

; Campanharo, Cássia Regina Vancini

; Batista, Ruth Ester Assayag

; Fernandes, Hugo

; Okuno, Meiry Fernanda Pinto

Cogitare Enfermagem

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2023, Volume 28 elocation e90260

Resumo: En Pt Es | Texto: En Pt Es | PDF: En | PDF: Pt | PDF: Es

ABSTRACT Objective: To identify factors related to burden and self-care for hypertension in family caregivers. Method: an online, cross-sectional survey of 68 family caregivers of elderly people, carried out between December 2021 and February 2022 in Brazil. Questionnaires on caregiver activity, the Informal Caregiver Burden Assessment Questionnaire and the Hypertension Self-Care Scale were applied. Descriptive and analytical analyses were carried out. Results: caregivers who lived with the elderly (p=0.0006) and had no rest day (p=0.0097) showed greater burden. The longer the time as a caregiver (p=0.0411), the lower the score in the domain of self-care management measures during blood pressure decompensation. Caregivers who received help from someone else (p=0.0379) had a higher score in the domain of the patient’s degree of confidence in self-care related to hypertension. Conclusion: This study contributes to a better understanding of the variables relating to caregiver activity related to burden and self-care for hypertension among caregivers of elderly people.

RESUMO Objetivo: identificar os fatores relacionados à sobrecarga e ao autocuidado para hipertensão em cuidadores familiares. Método: pesquisa online e transversal, com 68 cuidadores familiares de pessoas idosas, realizada entre dezembro de 2021 e fevereiro de 2022, no Brasil. Foram aplicados questionários sobre atividade de cuidador, Questionário de Avaliação da Sobrecarga do Cuidador Informal e Escala Autocuidado de Hipertensão. Foram realizadas análises descritivas e analíticas. Resultados: cuidadores que residiam com idoso (p=0,0006) e sem dia de descanso (p=0,0097) apresentaram maior sobrecarga. Quanto maior o tempo como cuidador (p=0,0411), menor o escore do domínio medidas de manejo do autocuidado durante a descompensação pressórica. Cuidadores que recebiam auxílio de outra pessoa (p=0,0379) apresentaram maior escore no domínio grau de confiança do paciente para o autocuidado relacionado à hipertensão. Conclusão: este estudo contribui para maior compreensão das variáveis referentes à atividade de cuidador relacionada à sobrecarga e ao autocuidado para hipertensão de cuidadores de pessoas idosas.

RESUMEN Objetivo: identificar los factores relacionados con la carga y el autocuidado de la hipertensión en cuidadores familiares. Material y método: encuesta transversal online a 68 cuidadores familiares de ancianos, realizada entre diciembre de 2021 y febrero de 2022 en Brasil. Se aplicaron cuestionarios sobre la actividad del cuidador, el Cuestionario de Evaluación de la Carga del Cuidador Informal y la Escala de Autocuidado de la Hipertensión. Se realizaron análisis descriptivos y analíticos. Resultados: los cuidadores que vivían con el anciano (p=0,0006) y no tenían día de descanso (p=0,0097) mostraron mayor carga. Cuanto mayor era el tiempo como cuidador (p=0,0411), menor era la puntuación en el dominio de las medidas de gestión del autocuidado durante la descompensación por presión. Los cuidadores que recibían ayuda de otra persona (p=0,0379) tenían una puntuación más alta en el dominio del grado de confianza del paciente en el autocuidado relacionado con la hipertensión. Conclusión: Este estudio contribuye a una mayor comprensión de las variables relativas a la actividad del cuidador relacionadas con la carga y el autocuidado de la hipertensión de los cuidadores de personas mayores.

https://doi.org/10.1590/ce.v28i0.90260

11.

Crop coefficient estimated by degree-days for ‘Marandu’ palisadegrass and mixed forage
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Pantojo de Souza, Débora Carniato Sanches, Arthur Campos Mendonça, Fernando Macedo Pezzopane, José Ricardo Morais Amorim, Danielle Lamede Ferreira de Jesus, Fernanda

Revista de la Facultad de Ciencias Agrarias. Universidad Nacional de Cuyo

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Dez 2021, Volume 53 Nº 2 Páginas 71 - 81

Resumo: Es En | Texto: Es En | PDF: Es | PDF: En

Resumen Considerando la importancia económica de los pastos, existe una necesidad de investigar los parámetros que afectan los coeficientes de cultivo utilizados para el manejo del riego. En este experimento, nuestro objetivo fue determinar el coeficiente de cultivo del pasto ‘Marandu’ en función de la acumulación de grados-días y estimar el consumo de agua del cultivo puro (pasto ‘Marandu’) y del cultivo mixto (pasto ‘Marandu’ + avena negra + raigrás italiano) regí menes de cultivo. La investigación se llevó a cabo en la Escuela de Agricultura Luiz de Queiroz en Piracicaba/SP, Brasil, entre 2016 y 2017, en este periodo se registró la evapotranspiración utilizando lisímetros de pesaje. La evapotranspiración del cultivo se calculó utilizando la variación de peso promedio registrada por lisímetros. Los datos de una estación meteoro lógica automatizada se utilizaron para estimar la evapotranspiración de referencia y calcular los grados-días. Se generaron ecuaciones y modelos de regresión con relación al coeficiente de cultivo y los grados-días acumulados durante dos períodos estacionales (primavera/verano y otoño/invierno). Los modelos matemáticos se probaron durante dos ciclos anuales, de 2015 a 2018 y mostraron mejores resultados, en términos de precisión y exactitud, en el sistema de cultivo único en primavera/verano en los años 2017/18.

Abstract Considering profitability in pasture-based systems, investigating parameters affecting crop coefficients for irrigation management becomes important. In this experiment, we determined the crop coefficient of ‘Marandu’ palisadegrass based on accumulated degree-days and estimated plant water consumption under single (‘Marandu’ palisade grass) and mixed (‘Marandu’ palisadegrass + black oats + Italian ryegrass) cropping regimes. The research was conducted at the Luiz de Queiroz College of Agriculture in Piracicaba, São Paulo, Brazil, between 2016 and 2017. Evapotranspiration was assessed using weighing lysimeters while crop evapotranspiration was calculated using mean weight variation. Reference evapotranspiration and degree-days were estimated. Data were obtained from an automated weather station. Equations and regression models relating crop coefficient with accumulated degree-days were generated for two seasons (spring/summer and autumn/ winter) and evaluated for two year-cycles, from 2015 to 2018. The results showed better prediction accuracy for the single cropping system in spring/summer 2017-18.

12.

Family structure, sociodemographic factors and type of dental service associated with oral health literacy in the early adolescence
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Lopes, Roanny Torres

; Neves, Érick Tássio Barbosa

; Gomes, Monalisa Cesarino

; Paiva, Saul Martins

; Ferreira, Fernanda Morais

; Granville-Garcia, Ana Flávia

Ciência & Saúde Coletiva

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Out 2021, Volume 26 Supl. 3 Páginas 5241 - 5250

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo Este estudo avaliou a associação de fatores sociodemográficos, familiares e do tipo de serviço odontológico utilizado ao alfabetismo em saúde bucal em pré-adolescentes. Trata-se de um estudo transversal com 740 escolares. Foram avaliados o alfabetismo em saúde bucal (BREALD-30), fatores sociodemográficos, tipo de serviço odontológico e funcionalidade familiar (FACES III) por meio de questionários validados. A associação entre as variáveis foi avaliada por meio de regressão de Poisson robusta (α=5%). Um maior alfabetismo em saúde bucal foi associado ao sexo feminino (RR=1.09; IC95%: 1.03-1.14), coesão familiar do tipo conectada (RR=1.12; IC95%: 1.05-1.20), adaptabilidade familiar dos tipos rígida (RR=1.14; IC95%: 1.04-1.25) e estruturada (RR=1.11; IC95%: 1.04-1.20), escolaridade materna superior a oito anos de estudo (RR=1.16; IC95%: 1.10-1.22), idade do responsável superior a 38 anos (RR=1.07; IC95%: 1.02-1.13) e uso de serviços odontológicos privados (RR=1.06; IC95%: 1.01-1.12). O nível de alfabetismo em pré-adolescentes foi associado ao sexo, estrutura familiar, idade e escolaridade do responsável e tipo de serviço odontológico utilizado.

Abstract The aim of this study was to evaluate associations between oral health literacy and family, sociodemographic and dental service characteristics in early adolescents. A cross-sectional study was conducted with 740 schoolchildren. The following variables were investigated using validated questionnaires: oral health literary (BREALD-30), sociodemographic characteristics, type of dental service and family functioning (FACES III). Associations were tested using robust Poisson regression analysis (α=5%). Higher oral health literacy was associated with the female sex (RR=1.09; 95%CI: 1.03-1.14), connected type of family cohesion (RR=1.12; 95%CI: 1.05-1.20), rigid (RR=1.14; 95%CI: 1.04-1.25) and structured (RR=1.11; 95%CI: 1.04-1.20) types of family adaptability, more than eight years of mother’s schooling (RR=1.16; 95%CI: 1.10-1.22), age of caregiver more than 38 years (RR=1.07; 95%CI: 1.02-1.13) and the use of private dental services (RR=1.06; 95%CI: 1.01-1.12). The level of oral health literacy in early adolescents was associated with sex, family structure, mother’s schooling, caregiver’s age and type of dental service used.

https://doi.org/10.1590/1413-812320212611.3.34782019

13.

Family and contextual factors associated with licit drug use in adolescence
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Gomes, Monalisa Cesarino

; Granville-Garcia, Ana Flávia

; Neves, Erick Tássio Barbosa

; Dutra, Laio da Costa

; Ferreira, Fernanda Morais

; Paiva, Saul Martins

Revista de Saúde Pública

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2021, Volume 55 elocation 95

Resumo: En | Texto: En | PDF: En

ABSTRACT OBJECTIVE: TO evaluate the family and contextual factors associated with licit drug use among 15 to 19-year-old adolescents in the school context. METHODS: This is a representative, school-based, cross-sectional study conducted with 746 adolescents from 15 to 19 years old enrolled in public and private schools. Parents/guardians reported on the sociodemographic variables, while adolescents answered questionnaires on drug use, family cohesion and adaptability, oral health literacy and visits to the dentist. Information on school context was obtained at the institution and via municipal publications. Associations between variables were analyzed using unadjusted and adjusted multilevel Poisson regression models. RESULTS: Prevalence of licit drug use at least once and a pattern indicative of harmful drug use were 39.8% and 15.1%, respectively. After the adjusted analysis of licit drug use at least once, the variables gender (PR = 1.26; 95%CI: 1.01–1.59), family cohesion (PR = 9.81; 95%CI: 1.23–72.54), and average income of the school district (PR = 0.72; 95%CI: 0.57–0.91) remained in the final model. As for drug abuse, only the detached type (PR = 23.01; 95%CI: 2.46–214.87) and separated type (PR = 13.54; 95%CI: 1.40–130.97) of family cohesion remained in the final model. CONCLUSION: Experience with licit drug use was associated with family and contextual factors among the adolescents, while family cohesion was the main factor related to harmful drug use.

https://doi.org/10.11606/s1518-8787.2021055003531

14.

Contributions of school context to caries on anterior teeth: a multilevel analysis
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Prata, Isolda Mirelle de Lima Ferreira

; Neves, Érick Tássio Barbosa

; Lima, Larissa Chaves Morais de

; Dutra, Laio da Costa

; Ferreira, Fernanda Morais

; Paiva, Saul Martins

; Granville-Garcia, Ana Flávia

Revista de Saúde Pública

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2021, Volume 55 elocation 111

Resumo: En | Texto: En | PDF: En

ABSTRACT OBJECTIVE To investigate whether oral health literacy (OHL) and school context are associated with untreated dental caries on the anterior teeth of adolescents. METHODS A representative cross-sectional study was conducted with 746 students aging 15 to 19 in the city of Campina Grande, Brazil. The guardians answered a questionnaire addressing sociodemographic data and the absence/presence of private health insurance. Two examiners were trained for the diagnosis of dental caries using the Nyvad criteria and the measurement of OHL using the Brazilian Rapid Estimate of Adult Literacy in Dentistry (BREALD-30) (Kappa > 0.80). Contextual aspects of the schools were obtained from the 2017 National School Census. Descriptive statistics were conducted, followed by unadjusted and adjusted robust negative binomial regression for complex samples (p < 0.05). RESULTS The average number of anterior teeth with untreated caries was 0.95 (SD = 1.77). Among individual factors, the male sex (RR = 1.64; 95%CI: 1.24–2.16), inadequate level of OHL (RR = 2.03; 95%CI: 1.13–1.63), marginal level of OHL (RR = 1.87; 95%CI: 1.05–3.33) and not having private health insurance (RR = 1.34; 95%CI: 1.07–1.68) were associated with untreated caries on anterior teeth. Among school contextual factors, the number of students in the classroom (RR = 2.64; 95%CI: 1.78–3.93), number of public oral health services in the district (RR = 0.14; 95%CI: 0.05–0.39) and average income of the district in which the school is located (RR = 0.99; 95%CI: 0.98–0.99) were associated with the outcome. CONCLUSIONS Sociodemographic factors, having private health insurance, OHL, and school context exerted an influence on the occurrence of untreated dental caries on anterior teeth in adolescents aging 15 to 19.

https://doi.org/10.11606/s1518-8787.2021055003929

15.

Identification of clusters of asthma control: A preliminary analysis of the Inspirers studies
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Jácome, Cristina Amaral, Rita Almeida, Rute Pereira, Ana Margarida Couto, Mariana Araújo, Luís Alves-Correia, Magna Pereira, Mariana Ferreira-Magalhães, Manuel Loureiro, Cláudia Chaves Catarata, Maria Joana Santos, Lília Maia Cabral, Sara Pereira, João Ramos, Bárbara Lopes, Cristina Mendes, Ana Lopes, Anabela Rodrigues, José Carlos Cidrais Oliveira, Georgeta Aguiar, Ana Paula Afonso, Ivete Carvalho, Joana Arrobas, Ana Maria Costa, José Valério, Margarida Pereira, Marta Almeida, Teresa Dias, Joana Bom, Ana Todo Azevedo, João Ribeiro, Carmelita Alves, Marta Pinto, Paula Leiria Neuparth, Nuno Neves, Ana Castro Palhinha, Ana Marques, João Gaspar Martins, Pedro Trincão, David Pina Todo-Bom, Filipa Santos, Maria Alvarenga Branco, Joana Costa, Alberto Neto, Armandina Silva Santalha, Marta Lozoya, Carlos Santos, Natacha Silva, Diana Vasconcelos, Maria João Barata, Luís Taborda Teixeira, Maria Fernanda Pinto, Diana Alves, Rodrigo Rodrigues Moreira, Ana Sofia Pinto, Cláudia Sofia Silva, Pedro Morais Alves, Carlos Câmara, Raquel Coelho, Didina Bordalo, Diana Carvalho, Fernanda Fernandes, Ricardo Ferreira, Rosário Oliveira, José Ferraz de Menezes, Fernando Gomes, Ricardo Calix, Maria José Marques, Ana Cardoso, João Emiliano, Madalena Gerardo, Rita Nunes, Carlos Ferreira, José Alberto Lopes, Inês Alves, Adelaide Fonseca, João Almeida

Revista Portuguesa de Imunoalergologia

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Dez 2020, Volume 28 Nº 4 Páginas 231 - 240

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Objetivos: Identificar clusters de controlo da asma baseados no Teste de Controlo da Asma e Rinite Alérgica (CARAT) e comparar as características dos doentes nos diferentes clusters. Métodos: Adultos e adolescentes (≥13 anos) com asma persistente foram recrutados em 29 centros no contexto de 2 estudos observacionais do projeto INSPIRERS. Foram recolhidos dados relativos a características demográficas e clínicas, adesão ao inalador, crenças sobre a medicação, sintomas de ansiedade e depressão, qualidade de vida e controlo da asma (CARAT, >24 bom controlo). Foi efetuada uma análise hierárquica de clusters usando a pontuação total do CARAT (CARAT-T).Resultados: Foram analisados 410 doentes (68% adultos), com uma idade mediana (percentil 25-percentil 75) de 28 (16-46) anos. Foram identificados três clusters [média CARAT-T(min-max)]: cluster 1 [27(24-30)], cluster 2 [19(14-23)] e cluster 3 [10(2-13)]. Os doentes no cluster 1 (34%) apresentavam melhor controlo da asma, melhor qualidade de vida, maior adesão aos inaladores e usavam um único inalador. Os doentes nos clusters 2 (50%) e 3 (16%) tinham a asma não controlada, menor adesão aos inaladores, mais sintomas de ansiedade e depressão e mais de metade reportavam pelo menos uma exacerbação no último ano. Adicionalmente, os doentes no cluster 3 eram predominantemente mulheres, tinham mais consultas médicas não agendadas, apresentavam mais sintomas de ansiedade, percebiam uma maior necessidade dos inaladores, mas também uma maior preocupação associada ao seu uso. Não se verificaram diferenças na idade, índice de massa corporal, função pulmonar, hábitos tabágicos, hospitalizações ou tempo de seguimento pelo médico especialista. Conclusões: Um método não supervisionado baseado no CARAT-T, identificou 3 clusters de doentes com diferentes características clínicas. O cluster com melhor controlo apresenta um ponto de corte semelhante ao estabelecido no estudo de validação do CARAT. Este estudo sugere ainda a existência de um ponto de corte adicional para distinguir doença mais grave. Mais investigação é necessária para validar os clusters identificados

Aims: To identify distinct asthma control clusters based on Control of Allergic Rhinitis and Asthma Test (CARAT) and to compare patients’ characteristics among these clusters. Methods: Adults and adolescents (≥13 years) with persistent asthma were recruited at 29 Portuguese hospital outpatient clinics, in the context of two observational studies of the INSPIRERS project. Demographic and clinical characteristics, adherence to inhaled medication, beliefs about inhaled medication, anxiety and depression, quality of life, and asthma control (CARAT, >24 good control) were collected. Hierarchical cluster analysis was performed using CARAT total score (CARAT-T). Results: 410 patients (68% adults), with a median (percentile 25-percentile 75) age of 28 (16-46) years, were analysed. Three clusters were identified [mean CARAT-T (min-max)]: cluster 1 [27(24-30)], cluster 2 [19(14-23)] and cluster 3 [10(2-13)]. Patients in cluster 1 (34%) were characterised by better asthma control, better quality of life, higher inhaler adherence and use of a single inhaler. Patients in clusters 2 (50%) and 3 (16%) had uncontrolled asthma, lower inhaler adherence, more symptoms of anxiety and depression and more than half had at least one exacerbation in the previous year. Furthermore, patients in cluster 3 were predominantly female, had more unscheduled medical visits and more anxiety symptoms, perceived a higher necessity of their prescribed inhalers but also higher levels of concern about taking these inhalers. There were no differences in age, body mass index, lung function, smoking status, hospital admissions or specialist physician follow-up time among the three clusters. Conclusion: An unsupervised method based on CARAT-T, identified 3 clusters of patients with distinct, clinically meaningful characteristics. The cluster with better asthma control had a cut-off similar to the established in the validation study of CARAT and an additional cut-off seems to distinguish more severe disease. Further research is necessary to validate the asthma control clusters identified.

https://doi.org/10.32932/rpia.2020.12.046

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