RESUMEN Introducción y objetivos: El tratamiento de los pacientes con fibrilación auricular no valvular (FANV) que requieren implante de stents coronarios es un desafío. El objetivo del estudio fue investigar si el cierre de la orejuela izquierda (COI) podría ser una opción posible y beneficiosa para estos pacientes. Para ello, se analiza el impacto del COI más tratamiento antiagregante plaquetario (AP) en comparación con la combinación de anticoagulantes orales (ACO), incluidos los ACO directos, y tratamiento AP en los resultados a largo plazo de estos pacientes Métodos: Se analizaron los resultados de 207 pacientes con FANV sometidos consecutivamente a implante de stents coronarios. Recibieron ACO 146 pacientes (74 acenocumarol, 71 ACO de acción directa) y en 61 se realizó COI. La mediana de seguimiento fue de 35 meses. Los pacientes también recibieron tratamiento AP por prescripción de su cardiólogo. El estudio recibió la debida supervisión ética. Resultados: La edad (media: 75,7 años) y el antecedente de accidente vascular cerebral fueron similares en ambos grupos, aunque el grupo de COI presentó más características desfavorables (antecedente de enfermedad de las arterias coronarias [CHA2DS2-VASc], antecedente de hemorragias significativas [BARC ≥ 2] y HAS-BLED). La aparición de acontecimientos adversos graves (muerte, accidente vascular cerebral, accidente isquémico transitorio, hemorragia grave) y cardiovasculares graves (muerte de causa cardiaca, accidente vascular cerebral, accidente isquémico transitorio, infarto de miocardio) fue significativamente mayor en el grupo de ACO que en el de COI: 19,75 frente a 9,06% (HR = 2,18; p = 0,008) y 6,37 frente a 1,91% (HR = 3,34; p = 0,037), respectivamente. Conclusiones: La combinación de COI y tratamiento AP en pacientes con FANV conlleva mejor pronóstico clínico a largo plazo que el tratamiento con ACO y terapia AP, a pesar de las características basales desfavorables del grupo de COI.

ABSTRACT Introduction and objectives: The treatment of patients with non-valvular atrial fibrillation (NVAF) who need coronary stenting is challenging. The objective of the study was to determine whether left atrial appendage occlusion (LAAO) could be a feasible option and benefit these patients. To this end, we studied the impact of LAAO plus antiplatelet drugs vs oral anticoagulants (OAC) (including direct OAC) plus antiplatelet drugs in these patients' long-term outcomes. Methods: The results of 207 consecutive patients with NVAF who underwent coronary stenting were analyzed. A total of 146 patients were treated with OAC (75 with acenocoumarol, 71 with direct OAC) while 61 underwent LAAO. The median follow-up was 35 months. Patients also received antiplatelet therapy as prescribed by their cardiologist. The study received the proper ethical oversight. Results: Age (mean 75.7 years), and the past medical history of stroke were similar in both groups. However, the LAAO group had more unfavorable characteristics (history of coronary artery disease [CHA2DS2-VASc], and significant bleeding [BARC ≥ 2] and HAS-BLED). The occurrence of major adverse events (death, stroke/transient ischemic events, major bleeding) and major cardiovascular events (cardiac death, stroke/transient ischemic attack, and myocardial infarction) were significantly higher in the OAC group compared to the LAAO group: 19.75% vs 9.06% (HR, 2.18; P = .008) and 6.37% vs 1.91% (HR, 3.34; P = .037), respectively. Conclusions: In patients with NVAF undergoing coronary stenting, LAAO plus antiplatelet therapy produced better long-term outcomes compared to treatment with OAC plus antiplatelet therapy despite the unfavorable baseline characteristics of the LAAO group.

Abstract The effectiveness of seismic dampers to improve the lateral performance of timber structures may be heavily diminished if restrictive lateral drift limits as set by building codes, governs the design of the structure. This paper presents an innovative approach to improve the performance of seismic dampers installed in stiff wood-frame shear walls. U-Shape Flexural Plate dampers with a novel internal restraint system, were installed in a 4880x2475 mm wood-frame shear wall with an Eccentric Lever-Arm System which aimed at amplifying the displacements by transferring them from the shear wall to the dampers. Cyclic tests were conducted to four specimens. Initial test results showed that the presented amplifying system suffered concentrated losses of stiffness at some connections joints reducing its real efficiency. The loss of displacement transmission to dampers was retrofitted, and the results showed a great benefit in terms of resilience for the damped shear wall in contrast with unprotected ones. It was found that this approach provides a feasible solution to enhance the lateral performance of wood-frame structures.

Abstract Bibliometric analysis is useful for quantitative and qualitative analysis of scientific-technical publications, as well as establishing topics and research areas. Universities produce scientific and technical knowledge through degree projects developed by their students, but it has not received the same treatment as other dissemination forms such as scientific papers or conference presentations. In this sense, a bibliometric analysis of degree projects on tourism from Universities of Ecuador has not been done. Hence, this research states as objective the systematization of undergraduate and graduate degree projects from eight Universities of Pichincha, Napo, and Orellana provinces, which have programs on tourism, hospitality, and gastronomy. The available information in digital repositories was systematized from the period of 2000 to 2017. Descriptive statistics and bibliometric indexes were applied. As a result, 3.185-degree projects were collected, most of them (98%) were from undergraduate programs. 62% of degree projects were identified and focused on economic and administrative topics based on the private sector mainly in Pichincha (especially in Quito’s Downtown and La Mariscal neighborhoods), Cotopaxi and Imbabura provinces. Community-based and cultural tourism topics, mainly in Highlands and Amazonia, and tourism development for the territories were also addressed. Universities with greater productivity, levels of collaboration and bigger research teams were identified. The literature cited is not up-to-date and it comes mainly from Mexico and Spain. The results obtained can be an important input for public, private, and community sectors and mainly for Academia, which could focus its further researches on topics and least studied areas.

Resumen El análisis bibliométrico es útil para analizar la cantidad y la calidad de las publicaciones científico-técnicas, como las temáticas y áreas de estudio. Las universidades generan producción científico-técnica a través de los trabajos de titulación que desarrollan sus estudiantes, pero no han recibido el mismo tratamiento de otras formas de divulgación como artículos científicos o ponencias a congresos. En este sentido, en Ecuador no se han realizado análisis bibliométricos de los trabajos de titulación sobre turismo desarrollados en sus universidades. Por ello, se planteó como objetivo sistematizar los trabajos de titulación de pregrado y posgrado de ocho universidades de las provincias de Pichincha, Napo y Orellana, que poseen carreras relacionadas con turismo, hospitalidad y gastronomía, en el período 2000-2017. Se sistematizó la información disponible en los repositorios digitales, se aplicó estadística descriptiva y se calcularon índices bibliométricos. Como resultado se recopilaron 3.185 trabajos de titulación, principalmente de pregrado (98%). Se identificó que el 62% se enfocan en temas económicos y administrativos, orientados al sector privado, concentrados en Pichincha (especialmente en el Centro Histórico y La Mariscal), Cotopaxi e Imbabura. Otras temáticas tratadas son turismo comunitario y cultural, principalmente en la Sierra y Amazonía, y desarrollo turístico de los territorios. Se identificaron las universidades con mayor productividad y grado de colaboración y, con los grupos de investigación más grandes. La literatura citada tiene un envejecimiento alto, principalmente de México y España. Los resultados obtenidos pueden ser un insumo importante para los sectores público, privado y comunitario, y en especial la academia, que podría enfocar futuras investigaciones en temáticas y zonas poco estudiadas.

Abstract The FEMA P-695 report presents a methodology for the rational quantification of seismic performance factors for use in seismic design. Despite the fact that the methodology is comprehensive and covers a wide range of possible applications, it only provides ground motion sets recorded from shallow crustal earthquakes. Therefore, this paper presents a new set of ground motions aimed at extending the scope of the FEMA P-695 methodology to zones prone to subduction earthquakes. To consider the effect of spectral shapes on collapse capacities, the spectral shape factors SSF were also computed. Four light-frame buildings were analyzed to study the impact of using the new ground motion set. Results showed a decrease in collapse capacities of 12.4%, an increase in peak floor accelerations of 31.7%, and an increase in the dissipated hysteretic energy of 15.7%. Additionally, the number of ground motions and the intensity levels of the set proved to be robust enough to provide the same reliability that can be obtained when employing a much larger ground motion set. The ground motions and the information provided in this paper have been designed to be fully consistent with the FEMA P-695 guidelines. However, their application can be extended to other analyses that evaluate the seismic performance of structural systems in subduction areas. A database that includes the proposed ground motion set is available online.