ABSTRACT Cardiac tumors are rare and encompass a variety of presentations. Clinica symptoms are usually nonspecific, but they can present as obstructive, embolic, or constitutional symptoms. Treatment options and prognosis vary highly depending on the subtype, tumor size, and location. Surgical resection is usually the first-line therapy, except for cardiac lymphomas, and provides favorable long-term prognosis in most benign tumors. Cardiac sarcomas, however, are usually diagnosed in advanced stages, and the treatment relies on a multimodal approach with chemotherapy and radiotherapy. Metastatic cardiac tumors are usually related to advanced disease and carry an overall poor prognosis. presentations nonspecific obstructive embolic subtype size location firstline first line therapy lymphomas longterm long term sarcomas however stages radiotherapy

Objective This study aimed to evaluate the results of thyroid surgeries with hospitalization periods shorter than 18 hours performed in a surgical endocrinology service, correlating these results with type of procedure, the definitive diagnosis and complications associated with the procedure.Subjects and methods The procedures performed, complications associated, hospitalization period, and relationships among these variables were assessed in consecutive patients subjected to different types of thyroid surgeries from January 1997 to March 2014 by the same group of surgeons. Data were analyzed by frequency, and the associations between the hospitalization period and other variables were analyzed using the Pearson chi-square test and Fisher’s exact test, using a multiple comparisons test with Bonferroni correction.Results Among the 3,411 surgeries performed, 799 of them were malignant neoplasia, 2,505 were benign tumors and 107 were Graves’ disease. The following procedures were performed: total thyroidectomy (1597 patients); total thyroidectomy with neck exploration (369 patients); lobectomy plus isthmectomy (1084 patients); total thyroidectomy complementation (145 patients); total thyroidectomy with neck dissection (84 patients); modified radical total thyroidectomy (13 patients); nodulectomy (11 patients); unresectable (9 patients); central neck dissection (48 patients); lateral neck dissection (38 patients); and others (13 patients). The following surgical complications, characteristic of the procedure: hemorrhage in 41 (1.2%) patients, hypoparathyroidism in 10 (0.3%) patients and recurrent laryngeal nerve (RLN) injury in 23 (0.7%) patients. Hospitalization shorter than 18 hours was observed in 97% of patients.Conclusion Thyroid surgery can be safely performed in virtually all patients on an overnight basis in specialized services.

OBJETIVO: Descrever e analisar as principais complicações pós-operatórias e mortalidade dos pacientes submetidos à ressecção gástrica por câncer gástrico com linfadenectomia D2. MÉTODO: Foi realizada uma coorte histórica onde as principais variáveis em estudo foram: idade, localização do tumor, estadiamento, complicações do procedimento cirúrgico, padrão de recidiva tumoral, análise da sobrevida livre de doença e sobrevida total. RESULTADOS: Foram avaliados 35 pacientes submetidos à dissecção linfonodal D2 no período de Janeiro de 2000 a Dezembro de 2004. A média de idade foi 57 anos. Apenas um (2,9%) paciente apresentava tumor precoce e o local mais comum do tumor foi no terço médio do estômago. O número de linfonodos ressecados por paciente variou de 15 a 80 linfonodos (média 28,8). Vinte e seis (74,3%) pacientes apresentaram linfonodos metastáticos, sendo a média de 13,4 (±11,8) linfonodos comprometidos por paciente. Seis (17,1%) pacientes apresentaram complicações no período pós-operatório, sendo duas pneumonias, uma fístula pancreática, uma fístula do coto duodenal e duas deiscências da anastomose esôfago-jejunal. Apenas um (2,86%) paciente morreu devido a complicações operatórias. O tempo de seguimento médio foi de 26 meses. Vinte e dois pacientes apresentavam-se vivos no fechamento do estudo, com uma sobrevida atuarial de 62,9%. CONCLUSÃO: Os resultados deste estudo sugerem que, em centros especializados, a linfadenectomia D2 é um procedimento com nível de complicações aceitável e pode ser realizada sem aumento da mortalidade operatória.

BACKGROUND: The aim of this study was to describe and analyze the postoperative complications and the survival of patients submitted to gastric resection with extended lymphadenectomy. METHODS: In a historical cohort, data of patients with gastric carcinoma submitted to D2 lymphadenectomy were studied. The main variables analyzed were: age, tumor location, stage, surgical procedure complications, pattern of tumor recurrence and overall survival. RESULTS: Thirty-five patients were studied during the period between January 2000 and December 2004. Mean age of the patients was 57 years. Only one (2.9%) patient had early gastric cancer. The most common site was in the middle-third of the stomach. The number of resected nodes per patient ranged from 15 to 80 (mean of 28.8). Twenty-six (74.3%) patients had metastatic lymph nodes, with mean of 13.4 (±11.8) positive nodes per patient. Six (17.1%) patients had complications in the postoperative period, including two pneumonias, one pancreatic fistula, one duodenal stump fistula, and two esophagojejunal leakage. Only one (2.86%) patient died of operative complications. The meantime of follow-up was 26 months. Twenty-two patients were alive at the conclusion of the study, with a current actuarial survival of 62.9%. CONCLUSION: The results of this study suggest that, in specialized centers, gastrectomy with D2 lymphadenectomy is a procedure with acceptable levels of complications, and can be performed without increasing the postoperative mortality.

OBJETIVO: o presente estudo teve o objetivo de avaliar as alterações esqueléticas sagitais produzidas pelo aparelho de Herbst. METODOLOGIA: foram avaliados 22 indivíduos com má oclusão de Classe II, 1ª divisão, sendo 11 do gênero masculino e 11 do gênero feminino, com média de idade de 9,01 anos (±6 meses), apresentando padrão facial Classe II, deficiência mandibular e padrão esquelético de Classe II (ANB>5º e Co-Gn-Co-Sn<20mm), tratados consecutivamente com o aparelho Herbst por um período de 12 meses. Todos os indivíduos encontravam-se no período intertransitório da dentadura mista e no estágio pré-puberal. Para tal avaliação utilizaram-se telerradiografias de perfil obtidas em três tempos distintos: T1) inicial, T2) logo após a remoção do aparelho, T3) 2 anos após o final do tratamento. O grupo controle foi constituído de 105 indivíduos com má oclusão de Classe II esquelética, não tratados ortodonticamente, pareados quanto às idades óssea e cronológica ao grupo experimental. O tratamento estatístico foi realizado por meio da Análise de Variância (ANOVA), complementada pelo teste de Comparações Múltiplas de Tukey e Teste t de Student, com nível de significância de 5%. RESULTADOS E CONCLUSÕES: os resultados evidenciaram um efeito clinicamente insignificante de restrição do crescimento maxilar, um estímulo do crescimento mandibular e um posicionamento mais anterior da mandíbula, contribuindo para uma melhora significativa na relação entre as bases apicais. Após 12 meses de tratamento, estas alterações esqueléticas sagitais contribuíram em cerca de 41% para correção da relação molar de Classe II e em 65% para correção do trespasse horizontal. No final do período de 2 anos pós-remoção do aparelho, houve uma tendência de redução da magnitude das alterações induzidas, no entanto uma melhora significativa na relação entre as bases apicais, no trespasse horizontal e na relação molar foram evidentes.

AIM: the present study aimed at evaluating the sagittal skeletal alterations after Herbst appliance treatment. METHODS: the sample was comprised by in 22 subjects with Class II division 1 malocclusion, being 11 males and 11 females, with a mean age of 9.01 years (±06 months), who presented Class II facial pattern, mandibular deficiency and Class II skeletal pattern (ANB>5º and Co-Gn - Co-Sn <20mm) and were consecutively treated with the Herbst appliance for a mean period of 12 months. All subjects were on the intermediate period of the mixed dentition and on the pre-pubertal stage. Evaluation was performed on lateral cephalograms taken in three different moments: T1) initial, T2) soon after removal of the appliance, T3) 2 years after treatment completion. The control group was composed by 105 subjects with skeletal Class II malocclusion not submitted to orthodontic treatment, matched as to the bone and chronological ages of the study group. Statistical analysis was performed by means of Analysis of Variance (ANOVA), complemented by the Tukey test for multiple comparisons and the Student's t test, at a significance level of 5%. RESULTS AND CONCLUSION: the results revealed an not significant effect of restriction of the maxillary growth, stimulation of the mandibular growth and forward positioning of the mandible, which contributed to a significant improvement in the jaw relationship. These sagittal skeletal alterations accounted for about 41% of the correction of the Class II molar relationship and 65% of the overjet correction. At 2 years after removal of the appliance there was a tendency towards a reduction in the magnitude of the alterations achieved; however, significant improvements in the jaw relationship, overjet and molar relationship were noticeable.