SUMMARY OBJECTIVE: Inflammation plays a key role in the pathogenesis of postoperative atrial fibrillation after coronary artery bypass graft surgery. In this study, we aimed to investigate the changes in mean platelet volume and platelet values during the spring and autumn seasons in patients who underwent isolated coronary artery bypass graft surgery and the possible effect of these occurrences on postoperative atrial fibrillation. METHODS: Consecutive patients who underwent elective isolated coronary bypass surgery at our clinic in the spring and autumn months, between August 2020 and July 2022, were retrospectively included in this study. Variables were evaluated according to the spring and autumn seasons. Patients who did not develop in-hospital postoperative atrial fibrillation were identified as Group 1, and those who did constituted Group 2. RESULTS: A total of 622 patients were included in the study. The patients were divided into two groups: those who were operated on in the spring (n=277, median age=62 years, male gender ratio=77.3%) and those who were operated on in the autumn (n=345, median age=61 years, male gender ratio=81.4%). There was no statistically significant difference between the patients operated on in both seasons in terms of age, gender, hypertension rates, and the frequency of chronic obstructive pulmonary disease. In multivariate analysis, being over 70 years old (OR: 1.934, 95% confidence interval (CI) 1.489–2.995, p<0.001), having a left ventricular ejection fraction below 30% (OR: 1.550, 95%CI 1.190–2.236, p=0.012), and having chronic obstructive pulmonary disease (OR: 1.663, 95%CI 1.339–2.191, p<0.001) were found to be independent predictors in predicting the development of postoperative atrial fibrillation. CONCLUSION: In this study, we first demonstrated that mean platelet volume and platelet mass index values were higher in patients in the autumn months. Additionally, for the first time in the literature, we showed that there is a significant relationship between platelet mass index value and the development of postoperative atrial fibrillation in patients who underwent isolated coronary artery bypass graft. OBJECTIVE study METHODS months 202 2022 inhospital hospital 1 2 RESULTS 62 groups n=277, n277 n 277 (n=277 age62 age age=6 ratio=77.3% ratio773 ratio 77 3 n=345, n345 345 (n=345 age61 61 ratio=81.4%. ratio814 ratio=81.4% . 81 4 ratio=81.4%) rates analysis 7 OR (OR 1934 934 1.934 95 CI (CI 14892995 489 995 1.489–2.995 p<0.001, p0001 p p<0.001 , 0 001 30 1550 550 1.550 95CI 11902236 190 236 1.190–2.236 p=0.012, p0012 p=0.012 012 p=0.012) 1663 663 1.663 13392191 339 191 1.339–2.191 CONCLUSION Additionally literature 20 6 n=277 n27 27 (n=27 age6 age= ratio=77.3 ratio77 n=345 n34 34 (n=34 ratio81 ratio=81.4 8 193 93 1.93 9 1489299 48 99 1.489–2.99 p000 p<0.00 00 155 55 1.55 1190223 19 23 1.190–2.23 p001 p=0.01 01 166 66 1.66 1339219 33 1.339–2.19 n=27 n2 (n=2 ratio=77. ratio7 n=34 n3 (n=3 ratio8 ratio=81. 1.9 148929 1.489–2.9 p00 p<0.0 15 5 1.5 119022 1.190–2.2 p=0.0 16 1.6 133921 1.339–2.1 n=2 (n= ratio=77 n=3 ratio=81 1. 14892 1.489–2. p0 p<0. 11902 1.190–2. p=0. 13392 1.339–2. n= (n ratio=7 ratio=8 1489 1.489–2 p<0 1190 1.190–2 p=0 1339 1.339–2 ratio= 148 1.489– p< 119 1.190– p= 133 1.339– 14 1.489 11 1.190 13 1.339 1.48 1.19 1.33 1.4 1.1 1.3

ABSTRACT Postoperative pain after cardiac surgery plays an important role in the patient’s recovery process. In particular, pain at the chest tube site can negatively affect the comfort and recovery of these patients. Effective pain control minimizes the risk of many complications. Oral and intravenous analgesics, epidural anesthesia, paravertebral block, and intercostal nerve blockade are used in chest tube pain control. We routinely use the surgical cryoablation method in the presence of atrial fibrillation in the preoperative period of cardiac surgery in our clinic. Here we aimed to describe our method of using the cryoablation catheter for intercostal nerve blockade. patients patient s process particular complications analgesics anesthesia block clinic

SUMMARY OBJECTIVE: Postoperative acute kidney injury is an important problem that can occur after coronary artery bypass graft operations, and it is important to identify risky patient groups preoperatively. This study aimed to investigate the importance of preoperative syndecan-1 levels in predicting acute kidney injury after elective coronary artery bypass graft operations accompanied by cardiopulmonary bypass. METHODS: Patients who underwent coronary artery bypass graft operation in our clinic between March 1 and May 10, 2022, were included in this prospective study. Patients who did not develop acute kidney injury in the postoperative period were recorded as group 1 and patients who developed it were recorded as group 2. RESULTS: A total of 79 patients undergoing coronary artery bypass graft surgery with cardiopulmonary bypass were included in the study. There were 55 patients in group 1 and 24 patients in group 2. There was no difference between the groups in terms of age, gender, diabetes mellitus, body mass index, smoking, and hyperlipidemia rates. In multivariate logistic regression analysis, increased blood product use (odds ratio 1.634; 95%CI 1.036–2.579; p=0.035), preoperative high creatinine (odds ratio 59.387; 95%CI 3.034–1162.496; p=0.007), and high syndecan-1 (odds ratio 1.015; 95%CI 1.002–1.028; p=0.025) were independent predictors of acute kidney injury. CONCLUSION: This study revealed that elevated preoperative syndecan-1 is associated with acute kidney injury after isolated coronary artery bypass graft accompanied by cardiopulmonary bypass and has prognostic utility independent of other recognized risk factors. OBJECTIVE preoperatively syndecan1 syndecan syndecan- METHODS 10 2022 2 RESULTS 7 5 age gender mellitus index smoking rates analysis odds 1.634 1634 634 95CI CI 95 1.036–2.579 10362579 036 579 p=0.035, p0035 p p=0.035 , 0 035 p=0.035) 59.387 59387 59 387 3.034–1162.496 30341162496 3 034 1162 496 p=0.007, p0007 p=0.007 007 p=0.007) 1.015 1015 015 1.002–1.028 10021028 002 028 p=0.025 p0025 025 CONCLUSION factors 202 1.63 163 63 9 1.036–2.57 1036257 03 57 p003 p=0.03 59.38 5938 38 3.034–1162.49 3034116249 116 49 p000 p=0.00 00 1.01 101 01 1.002–1.02 1002102 02 p=0.02 p002 20 1.6 16 6 1.036–2.5 103625 p00 p=0.0 59.3 593 3.034–1162.4 303411624 11 4 1.0 1.002–1.0 100210 1. 1.036–2. 10362 p0 p=0. 59. 3.034–1162. 30341162 1.002–1. 10021 1.036–2 1036 p=0 3.034–1162 3034116 1.002–1 1002 1.036– 103 p= 3.034–116 303411 1.002– 100 1.036 3.034–11 30341 1.002 1.03 3.034–1 3034 1.00 3.034– 303 3.034 30 3.03 3.0 3.

Resumo Objetivo Avaliar o conhecimento, as atitudes e os comportamentos em relação aos métodos de medicina complementar e alternativa de pacientes internadas em ambulatórios de ginecologia. Métodos Na presente pesquisa, um questionário sobre práticas de medicina complementar e alternativa foi aplicado a 1.000 mulheres (idades entre 18 e 83 anos) que foram admitidas nos ambulatórios de ginecologia de uma maternidade terciária. Características demográficas e conhecimento, atitudes e comportamentos sobre esses métodos foram investigados em entrevistas pessoais. Resultados Enquanto 80,7% do total de participantes achavam que a medicina complementar e alternativa era benéfica, apenas 37,5% deles haviam usado esses métodos anteriormente. A taxa de conhecimento prévio sobre o assunto foi de 59,7% e a fonte de informação foi médica para 8,5% dos pacientes. No entanto, 72,4% de todos os participantes queriam obter informações sobre esses métodos e 93,7% queriam ser informados por médicos. No modelo de árvore de decisão, ter conhecimento sobre medicina complementar e alternativa foi o fator mais eficaz para determinar seu uso (p<0,001). A fitoterapia foi o método mais utilizado, com 91,4%. A planta preferida foi a cebola (18,9%), e osmotivos mais comuns para o uso de ervas foram estresse (15,4%) e fadiga (15,2%). Conclusão Mais de um terço das pacientes que se inscreveram no ambulatório de ginecologia utilizaram um dos métodos de medicina complementar e alternativa pelo menos uma vez. Como ginecologistas e obstetras, precisamos ter mais conhecimento sobre estes métodos a fimde fornecer orientações corretas aos nossos pacientes para o acesso a informações precisas e eficazes.

Abstract Objective To evaluate the knowledge, attitudes, and behaviors regarding complementary and alternative medicine methods of patients who were admitted to gynecology outpatient clinics. Methods In the present survey, a questionnaire on complementary and alternative medicine practices was applied on 1,000 women (ages between 18 and 83 years old) who were admitted to the gynecology outpatient clinic of a tertiarymaternity hospital. Demographic features and knowledge, attitudes, and behaviors about these methods were inquired in face-to-face interviews. Results While 80.7% of the total participants thought that complementary and alternative medicine was beneficial, only 37.5% of them had used these methods previously. The rate of prior knowledge on this subject was of 59.7% and the source of information was physicians for 8.5% of the patients. However, 72.4% of all participants wanted to obtain information on these methods and 93.7% wanted to be informed by physicians. In the decision tree model, having knowledge about complementary and alternative medicine was the most effective factor determining its use (p<0.001). Phytotherapy was found to be the most used method, with 91.4%. The most preferred plant was onion (18.9%), and the most common reasons for herbal use were stress (15.4%) and fatigue (15.2%). Conclusion More than one-third of the patients who applied to the gynecology outpatient clinics used one of the complementary and alternativemedicine methods at least once. As gynecologists and obstetricians, we need to be more knowledgeable about these methods to provide correct guidance to our patients for accessing accurate and effective information.