Abstract Objectives: to evaluate the association between breastfeeding and Autism Spectrum Disorder (ASD) in children and adolescents. Methods: this is a case-control study carried out in the north of the state of Minas Gerais, Brazil, which included 248 children and adolescents diagnosed with ASD (case group) and 886 children and adolescents without a diagnosis of ASD (control group).Interviews were conducted with the mothers of children and adolescents and a semi-structured questionnaire was used to collect data. For data analysis, a multiple logistic regression model was adopted. The magnitude of associations was estimated by the odds ratio (OR). Three multiple models were fitted: Model 1: presence or absence of breastfeeding; Model 2: duration of breastfeeding; Model 3: duration of exclusive breastfeeding. Results: ASD was associated with the absence of breastfeeding in the three adjusted models: Model 1: OR=2.1, CI95%=1.1-4.1; Model 2: OR=2.3, CI95%=1.2-4.5; Model 3: OR=2.3, CI95%=1.2-4.5. Conclusions: individuals with ASD were more likely to have not received breastfeeding, however, due to the nature of case control studies, it cannot be stated that breastfeeding prevents ASD. Conducting a cohort study may clarify this relationship. Objectives (ASD Methods casecontrol Gerais Brazil 24 group 88 group.Interviews groupInterviews .Interviews Interviews semistructured semi structured analysis adopted OR. OR . (OR) fitted 1 2 3 Results OR21 OR=2.1 CI95%=1.14.1 CI951141 CI CI95%=1.1 4.1 CI95 4 CI95%=1.1-4.1 OR23 OR=2.3 CI95%=1.24.5 CI951245 CI95%=1.2 4.5 5 CI95%=1.2-4.5 CI95%=1.24.5. 4.5. Conclusions however studies relationship 8 (OR OR2 OR=2. 14 CI95%=1.14. CI95114 CI9511 CI95%=1. 41 4. CI9 CI95%=1.1-4. CI95%=1.24. CI95124 CI9512 45 CI95%=1.2-4. OR=2 CI95%=1.14 CI951 CI95%=1 CI95%=1.1-4 CI95%=1.24 CI95%=1.2-4 OR= CI95%= CI95%=1.1- CI95%=1.2- CI95%

Resumo Objetivos: avaliar a associação entre aleitamento materno e Transtorno do Espectro do Autismo (TEA) em crianças e adolescentes. Métodos: trata-se de um estudo caso-controle realizado no norte de Minas Gerais, Brasil, que incluiu 248 crianças e adolescentes com diagnóstico de TEA (grupo caso) e 886 crianças e adolescentes sem diagnóstico de TEA (grupo controle). Foram realizadas entrevistas com as mães das crianças e adolescentes e utilizado um questionário semiestruturado para coleta dos dados. Para análise dos dados foi adotado modelo de regressão logística múltipla. A magnitude das associações foi estimada pela Odds Ratio (OR). Três modelos múltiplos foram ajustados: Modelo 1: presença ou ausência de aleitamento materno; Modelo 2: duração do aleitamento materno; Modelo 3: duração do aleitamento materno exclusivo. Resultados: o TEA foi associado à ausência de aleitamento materno nos três modelos ajustados: Modelo 1: OR=2,1, IC95%=1,1-4,1; Modelo 2: OR=2,3, IC95%=1,2-4,5; Modelo 3: OR=2,3, IC95%=1,2-4,5. Conclusões: os indivíduos com TEA tiveram maiores chances de não terem recebido aleitamento materno, no entanto, devido à natureza dos estudos de caso-controle, não se pode afirmar que o aleitamento materno previna o TEA. A realização de um estudo de coorte poderá esclarecer essa relação. Objetivos (TEA Métodos tratase trata casocontrole caso controle Gerais Brasil 24 grupo 88 controle. . controle) múltipla OR. OR (OR) ajustados 1 2 3 exclusivo Resultados OR21 OR=2,1 IC95%=1,14,1 IC951141 IC IC95%=1,1 4,1 IC95 4 IC95%=1,1-4,1 OR23 OR=2,3 IC95%=1,24,5 IC951245 IC95%=1,2 4,5 5 IC95%=1,2-4,5 IC95%=1,24,5. 4,5. Conclusões entanto casocontrole, controle, relação 8 (OR OR2 OR=2, 14 IC95%=1,14, IC95114 IC9511 IC95%=1, 41 4, IC9 IC95%=1,1-4, IC95%=1,24, IC95124 IC9512 45 IC95%=1,2-4, OR=2 IC95%=1,14 IC951 IC95%=1 IC95%=1,1-4 IC95%=1,24 IC95%=1,2-4 OR= IC95%= IC95%=1,1- IC95%=1,2- IC95%

Abstract Objective: To determine the incidence of MIS-C in Brazil, describe the clinical and sociodemographic characteristics of the pediatric population affected by MIS-C and compare mortality and lethality outcomes with isolated Covid-19 and MIS-C cases. Methods: Observational and retrospective cohort study of cases of MIS-C associated with Covid-19 in the Brazilian population between 04/01/2020 and 04/17/2021. Data from the Ministry of Health's epidemiological bulletin up to the 15th epidemiological week of 2021, were used. The analyzes were descriptive through absolute and relative frequencies. The significance level is 5% in Stata 16.0 package. Results: Between 04/01/2020 and 04/07/2021, 903 cases of MIS-C associated with Covid-19 were notified in Brazil, of which, the largest part (55.26%) were male, between 0 and 4 years old (45.29%), from the Southeast region (38.76%). The deaths (61; 6.7%) were higher in the female gender, between 0 and 4 years old (47.54%) and in the Southeast region (34.43%). It was identified that the risk of death by MIS-C related to Covid-19 is 5.29 (CI = 2.83; 9.87 and P-value = <0.001) times higher in adolescents from 15-19 years old than in other age groups when compared to 0-4 years old children. Also, the residency in North region was as risk factor to death (RR = 3.72, IC = 1.29; 10.74 e P-value = 0.008). Conclusion: In this study, despite the numbers showing more deaths from zero to 4 years old, the risk for teenagers is notably higher. In addition, Brazil's Northern region is a risk factor that reaffirms social inequality and poor access to health. Objective MISC MIS C Brazil Covid19 Covid 19 Covid-1 Methods 04012020 04 01 2020 04/01/202 04172021 17 2021 04/17/2021 Healths Health s th used frequencies 5 160 16 16. package Results 04072021 07 04/07/2021 90 which 55.26% 5526 55 26 (55.26% male 45.29%, 4529 45.29% , 45 29 (45.29%) 38.76%. 3876 38.76% . 38 76 (38.76%) 61 (61 6.7% 67 6 7 gender 47.54% 4754 47 54 (47.54% 34.43%. 3443 34.43% 34 43 (34.43%) 529 5.2 CI 2.83 283 2 83 987 9 87 9.8 Pvalue P value <0.001 0001 001 1519 15 15-1 0- children Also RR 372 3 72 3.72 1.29 129 1 1074 10 74 10.7 0.008. 0008 0.008 008 0.008) Conclusion addition Brazils health Covid1 Covid- 0401202 202 04/01/20 0417202 04/17/202 0407202 04/07/202 55.26 552 (55.26 452 45.29 (45.29% 387 38.76 (38.76% (6 6.7 47.54 475 (47.54 344 34.43 (34.43% 52 5. 2.8 28 8 98 9. <0.00 000 00 151 15- 37 3.7 1.2 12 107 10. 0.00 040120 20 04/01/2 041720 04/17/20 040720 04/07/20 55.2 (55.2 45.2 (45.29 38.7 (38.76 ( 6. 47.5 (47.5 34.4 (34.43 2. <0.0 3. 1. 0.0 04012 04/01/ 04172 04/17/2 04072 04/07/2 55. (55. 45. (45.2 38. (38.7 47. (47. 34. (34.4 <0. 0. 0401 04/01 0417 04/17/ 0407 04/07/ (55 (45. (38. (47 (34. <0 040 04/0 041 04/17 04/07 (5 (45 (38 (4 (34 < 04/ 04/1 (3

Resumo: Introdução: A comunicação é uma competência essencial para o(a) médico(a) e outras categorias profissionais, e deve ser desenvolvida durante sua formação profissional. A elaboração de um projeto de comunicação, incluindo um consenso brasileiro, visou subsidiar as escolas médicas a preparar os estudantes de Medicina para se comunicarem efetivamente com os(as) cidadãos/cidadãs brasileiros(as), de características plurais intra e inter-regionais, pautando-se no profissionalismo e nos princípios do Sistema Único de Saúde (SUS). Objetivo: Este manuscrito apresenta o consenso para o ensino de comunicação nas escolas médicas brasileiras. Método: O consenso foi construído colaborativamente com 276 participantes, experts em comunicação, docentes, profissionais de saúde e discentes, de 126 escolas médicas e cinco instituições de saúde, ao longo de nove encontros presenciais em congressos e de encontros virtuais quinzenais ou mensais. Nos encontros, compartilharam-se as experiências dos participantes e o material bibliográfico, incluindo os consensos internacionais, e apresentou-se o consenso em construção, com discussão em grupos para elencar novos componentes para o consenso brasileiro, seguida por debate com todos para pactuá-los. A versão final foi aprovada em reunião virtual, com convite a todos(as) os(as) participantes em julho de 2021. Após submissão, diversas alterações foram requeridas, o que demandou novos encontros para revisão da versão final do consenso. Resultado: O consenso tem como pressupostos que a comunicação deve ser centrada nas relações, pautada nos princípios do SUS, na participação social e no profissionalismo, e embasada nas Diretrizes Curriculares Nacionais do curso de graduação em Medicina, em referenciais teóricos e nas evidências científicas. São descritos objetivos específicos para desenvolver a competência em comunicação nos estudantes, abrangendo: fundamentos teóricos; busca e avaliação crítica da literatura; elaboração e redação de documentos; comunicação intrapessoal e interpessoal no ambiente acadêmico-científico, na atenção à saúde em diversos contextos clínicos e na gestão em saúde. Recomenda-se a inserção curricular da comunicação do início ao final do curso, integrada a outros conteúdos e áreas de saber. Conclusão: Espera-se que esse consenso contribua para a revisão ou implementação da comunicação nos currículos das escolas médicas brasileiras.

Abstract: Introduction: Communication is an essential competence for the physician and other professional categories, and must be developed their professional training. The creation of a communication project including a Brazilian consensus aimed to subsidize medical schools in preparing medical students to communicate effectively with Brazilian citizens, with plural intra and inter-regional characteristics, based on the professionalism and the Brazilian Unified System (SUS) principles. Objective: The objective of this manuscript is to present the consensus for the teaching of communication in Brazilian medical schools. Method: The consensus was built collaboratively with 276 participants, experts in communication, faculty, health professionals and students from 126 medical schools and five health institutions in face-to-face conference meetings and biweekly or monthly virtual meetings. In the meetings, the participants’ experiences and bibliographic material were shared, including international consensuses, and the consensus under construction was presented, with group discussion to list new components for the Brazilian consensus, followed by debate with everyone, to agree on them. The final version was approved in a virtual meeting with invitation to all participants in July 2021. After the submission, several changes were required, which demanded new meetings to review the consensus final version. Result: The consensus is based on assumptions that communication should be relationship-centered, embedded on professionalism, grounded on the SUS principles and social participation, and based on the National Guidelines for the undergraduate medical course, theoretical references and scientific evidence. Specific objectives to develop communication competence in the students are described, covering: theoretical foundations; literature search and its critical evaluation; documents drafting and editing; intrapersonal and interpersonal communication in the academicscientific environment, in health care and in health management; and, communication in diverse clinical contexts. The inclusion of communication in the curriculum is recommended from the beginning to the end of the course, integrated with other contents and areas of knowledge. Conclusion: It is expected that this consensus contributes the review or implementation of communication in Brazilian medical schools’ curricula.