Pesquisa | SciELO

RESUMEN El dengue es un problema de salud pública mundial en especial cuando se trata de países con climas tropicales y subtropicales. Objetivo Describir las manifestaciones orales presentes durante la infección por dengue. Materiales y Método Se realizó una revisión sistemática cualitativa registrada en OSF Registries. La búsqueda se realizó en PubMed, Scielo y Scopus; desde el 15 de junio al 18 de julio del 2023, y se empleó ecuaciones de términos MeSH con operadores booleanos. Se obtuvieron 299 artículos analizados en tres etapas, quedando 8 investigaciones para su revisión. Se empleó RAYYAN para la selección y tablas para el análisis de los estudios. Se valoraron los estudios bajo dos criterios: metadatos y manifestaciones intraorales y extraorales por dengue. Resultados Se revisaron 8 estudios publicados en el 2012, 2013, 2014, 2019, 2020 y 2021. Reportaron como diagnóstico dengue hemorrágico y dengue tipo 1, señalaron la presencia de encías hemorrágicas y edematosas, lesiones maculopapulares en mucosa de labio inferior con dolor y disfagia; asimismo, se registró candidiasis pseudomembranosa, papilas gustativas edematosas y eritematosas. Conclusiones Los reportes de manifestaciones orales por dengue son deficientes, se requiere de más investigaciones para poder realizar un correcto diagnóstico y diferenciarlo de otras patologías.

ABSTRACT Dengue is a global public health problem, especially in countries with tropical and subtropical climates. Aim To describe the oral manifestations, present during dengue infection. Materials and method A qualitative systematic review was conducted in OSF Registries. The search was conducted in PubMed, Scielo and Scopus, from June 15 to July 18, 2023, using MeSH term equations with Boolean operators. A total 299 articles were analyzed in three stages, leaving 8 studies for review. RAYYAN was used for selection and tables for study analysis. Studies were assessed under two criteria: metadata, and intraoral and extraoral manifestations of dengue. Results The review included 8 studies, published in 2012, 2013, 2014, 2019, 2020 and 2021. The studies reported hemorrhagic dengue and type 1 dengue as diagnoses. They recorded presence of hemorrhagic and edematous gums, maculopapular lesions in the mucosa of the lower lip with pain and dysphagia, Pseudomembranous candidiasis, and edematous and erythematous taste buds. Conclusions Reports of oral manifestations of dengue are deficient, and further research is required to enable correct diagnosis and differentiation from other pathologies.

https://doi.org/10.54589/aol.37/2/114

Outcomes of ablative therapy and radical treatment for prostate cancer: a systematic review and meta-analysis cancer metaanalysis meta analysis
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Andrade, Guilherme Miranda

; Manente, Felipe Giorgi

; Barroso, Pedro José Damato Dias

; Teles, Saulo Borborema

; Partezani, Alexandre Dib

; Baccaglini, Willy

; Sanchez-Salas, Rafael

; Olivares, Ruben

; Nahar, Bruno

; Lemos, Gustavo Caserta

; Bianco, Bianca

; Carneiro, Arie

International braz j urol

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Jun 2024, Volume 50 Nº 3 Páginas 237 - 249

Resumo: En | Texto: En | PDF: En

ABSTRACT Purpose: To compare biochemical recurrence, sexual potency and urinary continence outcomes of ablative therapy and radical treatment (radical prostatectomy or radiotherapy with androgen deprivation therapy). Material and methods: A systematic review and meta-analysis followed the PRISMA guidelines were performed. We searched MEDLINE/PubMed. Biochemical recurrence at three and five years; incontinence rate (patients who used one pad or more) and erectile dysfunction rate at 12 and 36 months (patients who did not have sufficient erection to achieve sexual intercourse) were evaluated. The Mantel-Haenszel method was applied to estimate the pooled risk difference (RD) in the individual studies for categorical variables. All results were presented as 95% confidence intervals (95%CI). Random effects models were used regardless of the level of heterogeneity (I²). (PROSPERO CRD42022296998). Results: Eight studies comprising 2,677 men with prostate cancer were included. There was no difference in biochemical recurrence between ablative and radical treatments. We observed the same biochemical recurrence between ablative therapy and radical treatment within five years (19.3% vs. 16.8%, respectively; RD 0.07; 95%CI=-0.05, 0.19; I2=68.2%; P=0.08) and continence rate at 12 months (9.2% vs. 31.8%, respectively; RD −0.13; 95%CI, −0.27, 0.01; I2=89%; P=0.32). When focal treatment was analyzed alone, two studies with 582 patients found higher erectile function at 12 months in the ablative therapy group than in the radical treatment (88.9% vs. 30.8%, respectively; RD −0.45; 95%CI −0.84, −0.05; I2=93%; P=0.03). Conclusion: Biochemical recurrence and urinary continence outcomes of ablative therapy and radical treatment were similar. Ablative therapy appears to have a high rate of sexual potency. Purpose therapy. . therapy) methods metaanalysis meta analysis performed MEDLINEPubMed MEDLINE PubMed MEDLINE/PubMed more 1 3 intercourse evaluated MantelHaenszel Mantel Haenszel (RD variables 95 95%CI. 95CI CI (95%CI) I². I² I (I²) PROSPERO CRD42022296998. CRD42022296998 CRD CRD42022296998) Results 2677 2 677 2,67 included treatments 19.3% 193 19 (19.3 vs 168 16 8 16.8% respectively 0.07 007 0 07 95%CI=0.05, 95CI005 95%CI= 0.05, 05 95%CI=-0.05 0.19 019 I2=68.2% I2682 I2 68 P=0.08 P008 P 08 9.2% 92 9 (9.2 318 31 31.8% −0.13 013 13 027 27 −0.27 0.01 001 01 I2=89% I289 89 P=0.32. P032 P=0.32 32 P=0.32) alone 58 88.9% 889 88 (88.9 308 30 30.8% −0.45 045 45 084 84 −0.84 −0.05 005 I2=93% I293 93 P=0.03. P003 P=0.03 03 P=0.03) Conclusion similar (95%CI (I² CRD4202229699 267 67 2,6 19.3 (19. 16.8 0.0 00 95%CI=0.05 95CI00 0.05 95%CI=-0.0 0.1 I2=68.2 I268 6 P=0.0 P00 9.2 (9. 31.8 −0.1 02 −0.2 I2=89 I28 P03 P=0.3 5 88.9 (88. 30.8 −0.4 04 4 −0.8 −0.0 I2=93 I29 (I CRD420222969 26 2, 19. (19 16. 0. 95%CI=0.0 95CI0 95%CI=-0. I2=68. I26 P=0. P0 9. (9 31. −0. I2=8 88. (88 30. I2=9 CRD42022296 (1 95%CI=0. 95%CI=-0 I2=68 P=0 ( −0 I2= (8 CRD4202229 95%CI=0 95%CI=- I2=6 P= − CRD420222 CRD42022 CRD4202 CRD420 CRD42 CRD4

https://doi.org/10.1590/s1677-5538.ibju.2023.0628

[SciELO Preprints] - Guidelines on the Diagnosis and Treatment of Hypertrophic Cardiomyopathy – 2024
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Fernandes, Fabio Simões, Marcus V. Correia, Edileide de Barros Marcondes-Braga, Fabiana G. Coelho-Filho, Otavio Rizzi Mesquita, Cláudio Tinoco Mathias-Junior, Wilson Rochitte, Carlos Eduardo Ramires, Felix José Alvarez Alves, Silvia Marinho Martins Montera, Marcelo Westerlund Lopes, Renato Delascio Oliveira-Junior, Mucio Tavares Scolari, Fernando L. Avila, Walkiria Samuel Canesin, Manoel Fernandes Bacal, Fernando Bocchi, Edimar Alcides Moura, Lídia Ana Zytynski Saad, Eduardo Benchimol Scanavacca, Mauricio I. Valdigem, Bruno Pereira Cano , Manuel Nicolas Abizaid , Alexandre Ribeiro, Henrique Barbosa Lemos-Neto, Pedro Alves Ribeiro, Gustavo Calado de Aguiar Jatene, Fabio Biscegli Dias, Ricardo Ribeiro Beck-da-Silva, Luis Rohde, Luis Eduardo P. Bittencourt, Marcelo Imbroinise Pereira, Alexandre Krieger, José Eduardo Villacorta, Humberto Martins, Wolney de Andrade Figueiredo-Neto, José Albuquerque de Cardoso , Juliano Novaes Pastore, Carlos Alberto Jatene, Ieda Biscegli Tanaka, Ana Cristina Sayuri Hotta, Viviane Tiemi Romano, Minna Moreira Dias Albuquerque, Denilson Campos de Mourilhe-Rocha, Ricardo Hajjar, Ludhmila Abrahão Brito, Fabio Sandoli de Caramelli , Bruno Calderaro, Daniela Farsky, Pedro Silvio Colafranceschi , Alexandre Siciliano Pinto, Ibraim Masciarelli Vieira , Marcelo Luiz Campos Danzmann, Luiz Claudio Barberato , Silvio Henrique Mady, Charles Martinelli-Filho, Martino Torbey , Ana Flavia Malheiros Schwartzmann, Pedro Vellosa Macedo, Ariane Vieira Scarlatelli Ferreira , Silvia Moreira Ayub Schmidt, Andre Melo , Marcelo Dantas Tavares de Lima-Filho, Moysés Oliveira Sposito, Andrei C. Brito, Flavio de Souza Biolo, Andreia Madrini-Junior, Vagner Rizk, Stéphanie Itala Mesquita, Evandro Tinoco

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Data de publicação: 2024-04-08

Resumo: Pt Es En

A cardiomiopatia hipertrófica (CMH) é uma forma de doença do músculo cardíaco de causa genética, caracterizada pela hipertrofia das paredes ventriculares. O diagnóstico requer detecção por métodos de imagem (Ecocardiograma ou Ressonância Magnética Cardíaca) de qualquer segmento da parede do ventrículo esquerdo com espessura > 15 mm, sem outra causa provável. A análise genética permite identificar mutações de genes codificantes de diferentes estruturas do sarcômero responsáveis pelo desenvolvimento da CMH em cerca de 60% dos casos, permitindo o rastreio de familiares e aconselhamento genético, como parte importante do manejo dos pacientes e familiares. Vários conceitos sobre a CMH foram recentemente revistos, incluindo sua prevalência de 1 em 250 indivíduos, não sendo, portanto, uma doença rara, mas subdiagnosticada. A vasta maioria dos pacientes é assintomática. Naqueles sintomáticos, a obstrução do trato de saída do ventrículo esquerdo (OTSVE) é o principal distúrbio responsável pelos sintomas, devendo-se investigar a sua presença em todos os casos. Naqueles em que o ecocardiograma em repouso ou com Manobra de Valsalva não detecta gradiente intraventricular significativo (> 30 mmHg), devem ser submetidos à ecocardiografia com esforço físico para detecção da OTSVE.   Pacientes com sintomas limitantes e grave OTSVE, refratários ao uso de betabloqueadores e verapamil, devem receber terapias de redução septal ou uso de novas drogas inibidoras da miosina cardíaca. Por fim, os pacientes adequadamente identificados com risco aumentado de morta súbita podem receber medida profilática com implante de cardiodesfibrilador implantável (CDI).

La miocardiopatía hipertrófica (MCH) es una forma de enfermedad cardíaca de origen genético, caracterizada por el engrosamiento de las paredes ventriculares. El diagnóstico requiere la detección mediante métodos de imagen (Ecocardiograma o Resonancia Magnética Cardíaca) que muestren algún segmento de la pared ventricular izquierda con un grosor > 15 mm, sin otra causa probable. El análisis genético permite identificar mutaciones en genes que codifican diferentes estructuras del sarcómero responsables del desarrollo de la MCH en aproximadamente el 60% de los casos, lo que permite el tamizaje de familiares y el asesoramiento genético, como parte importante del manejo de pacientes y familiares. Varios conceptos sobre la MCH han sido revisados recientemente, incluida su prevalencia de 1 entre 250 individuos, por lo tanto, no es una enfermedad rara, sino subdiagnosticada. La gran mayoría de los pacientes son asintomáticos. En los casos sintomáticos, la obstrucción del tracto de salida ventricular izquierdo (TSVI) es el trastorno principal responsable de los síntomas, y su presencia debe investigarse en todos los casos. En aquellos en los que el ecocardiograma en reposo o la maniobra de Valsalva no detecta un gradiente intraventricular significativo (> 30 mmHg), deben someterse a ecocardiografía de esfuerzo para detectar la obstrucción del TSVI. Los pacientes con síntomas limitantes y obstrucción grave del TSVI, refractarios al uso de betabloqueantes y verapamilo, deben recibir terapias de reducción septal o usar nuevos medicamentos inhibidores de la miosina cardíaca. Finalmente, los pacientes adecuadamente identificados con un riesgo aumentado de muerte súbita pueden recibir medidas profilácticas con el implante de un cardioversor-desfibrilador implantable (CDI).

Hypertrophic cardiomyopathy (HCM) is a form of genetically caused heart muscle disease, characterized by the thickening of the ventricular walls. Diagnosis requires detection through imaging methods (Echocardiogram or Cardiac Magnetic Resonance) showing any segment of the left ventricular wall with a thickness > 15 mm, without any other probable cause. Genetic analysis allows the identification of mutations in genes encoding different structures of the sarcomere responsible for the development of HCM in about 60% of cases, enabling screening of family members and genetic counseling, as an important part of patient and family management. Several concepts about HCM have recently been reviewed, including its prevalence of 1 in 250 individuals, hence not a rare but rather underdiagnosed disease. The vast majority of patients are asymptomatic. In symptomatic cases, obstruction of the left ventricular outflow tract (LVOT) is the primary disorder responsible for symptoms, and its presence should be investigated in all cases. In those where resting echocardiogram or Valsalva maneuver does not detect significant intraventricular gradient (> 30 mmHg), they should undergo stress echocardiography to detect LVOT obstruction. Patients with limiting symptoms and severe LVOT obstruction, refractory to beta-blockers and verapamil, should receive septal reduction therapies or use new drugs inhibiting cardiac myosin. Finally, appropriately identified patients at increased risk of sudden death may receive prophylactic measure with implantable cardioverter-defibrillator (ICD) implantation.

https://doi.org/10.1590/SciELOPreprints.8394

Use of insect repellent as personal protection among women of childbearing age in an arbovirus endemic area in Northeastern Brazil
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Dias, Livia Karla Sales

; Sanhueza-Sanzana, Carlos

; Pinheiro Júnior, Francisco Marto Leal

; Martins, Adriano Ferreira

; Correia, Francisco Gustavo Silveira

; de Aguiar, Italo Wesley Oliveira

; Ferreira, Nayane Cavalcante

; Stolow, Jeni

; Rutherford, George

; Teixeira, Maria Gloria

; Pires Neto, Roberto da Justa

; de Almeida, Rosa Livia Freitas

; Coelho, Ivo Castelo Branco

; Frota, Cristiane Cunha

; Kendall, Carl

; Kerr, Ligia Regina Franco Sansigolo

Revista Brasileira de Epidemiologia

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2024, Volume 27 elocation e240025

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

https://doi.org/10.1590/1980-549720240025

Does GnRH treatment at TAI regardless of estrus occurrence increase pregnancy rate in crossbred Bos taurus suckled cows? cows
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Fernandes, Vanessa Silva

; Velho, Gabriella dos Santos

; Santos, Mateus Felipe Osório dos

; Evangelista, Kelly Alves

; Gasperin, Bernardo Garziera

; Pfeifer, Luiz Francisco Machado

; Ferreira, Rogério

; Gonçalves, Paulo Bayard Dias

; Gastal, Gustavo Desire Antunes

; Dalto, André Gustavo Cabrera

; Rovani, Monique Tomazele

Animal Reproduction

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2024, Volume 21 Nº 1 elocation e20230123

Resumo: En | Texto: En | PDF: En

Abstract The impact of GnRH treatment on the day of TAI in beef cows has received limited investigation, especially concerning its association with estrus expression. Consequently, two experiments were conducted to assess the potential of GnRH treatment on the day of TAI to enhance fertility according to the expression or not of estrus in beef cows. Experiment 1 aimed to determine ovulation rate and luteal function, while Experiment 2 aimed to determine the effect of the two GnRH treatment approaches on pregnancy rate. In Experiment 1, multiparous Brangus suckling cows (n = 17) were submitted to an 8-day TAI protocol. Estrus occurrence was evaluated based on chalk removal on D10 (TAI) and cows were assigned to receive GnRH (25µg lecirelin; im) according to the group: GnRH (n = 7), regardless of estrus expression; or selectGnRH (n = 10), only cows not detected in estrus. Ovulation rate occurring until 77h after IVD removal did not differ (p = 0.17) between GnRH (85.7%; 6/7) and selectGnRH (100%; 10/10). Also, corpus luteum size and serum progesterone concentration were not affected (p>0.05) by treatments. In Experiment 2, crossbred taurine suckled cows (n = 384) were submitted to the same protocol as described in Experiment 1 and were randomly allocated to GnRH or selectGnRH groups. There was no difference in P/AI between groups (selectGnRH = 55.6%; GnRH = 54.3%; p = 0.7) 30 days after TAI. As expected, there was a pronounced effect (p<0.0001) of estrus expression on P/AI (Estrus = 61.5%; No estrus = 33.0%), regardless of group. In summary, ovulation timing and rate and luteal function did not differ between groups. Also, GnRH administration only in cows that do not show estrus is recommended, considering hormone savings and similar conception rate. investigation Consequently n 17 8day 8 D D1 (TAI 25µg µg lecirelin im group 7, 7 , 7) 10, 10 10) h 0.17 017 0 85.7% 857 85 (85.7% 6/7 67 6 100% 100 (100% 10/10. 1010 10/10 . 10/10) Also p>0.05 p005 05 (p>0.05 treatments 384 PAI P AI 55.6% 556 55 54.3% 543 54 3 0.7 07 expected p<0.0001 p00001 0001 (p<0.0001 61.5% 615 61 5 33.0%, 330 33.0% 33 33.0%) summary recommended 0.1 01 85.7 (85.7 6/ (100 101 10/1 p>0.0 p00 (p>0.0 38 55.6 54.3 0. p<0.000 p0000 000 (p<0.000 61.5 33.0 85. (85. (10 10/ p>0. p0 (p>0. 55. 54. p<0.00 p000 00 (p<0.00 61. 33. (85 (1 p>0 (p>0 p<0.0 (p<0.0 (8 ( p> (p> p<0. (p<0. p<0 (p<0 p< (p<

https://doi.org/10.1590/1984-3143-ar2023-0123

Relative age effect on muscle power in Brazilian youth: a population study youth
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Bergmann, Gabriel Gustavo

; Mello, Júlio Brugnara

; Gaya, Adroaldo Cezar Araujo

; Fonseca, Fabiano de Souza

; Silva, Amanda Franco da

; Ferreira, Gustavo Dias

; Pinheiro, Eraldo dos Santos

Revista Brasileira de Cineantropometria & Desempenho Humano

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2024, Volume 26 elocation e98244

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo Este estudo teve como objetivo examinar o efeito da idade relativa na potência muscular em crianças e adolescentes brasileiros. A amostra foi composta por 87.766 meninas e meninos com idades entre 7 e 16 anos. Os participantes foram agrupados em quatro subgrupos etários dentro de cada idade cronológica tendo como base as datas de nascimento e da coleta dos dados. A potência muscular dos membros superiores e inferiores foi avaliada por meio dos testes de arremesso de medicine ball de 2 kg, e salto horizontal, respectivamente. A distribuição normativa (fraco; razoável; bom; muito bom; excelente) dos dois testes de potência foi utilizada para a classificação. Os resultados mostraram associação significativa entre os subgrupos etários e a classificação normativa da potência muscular. Entre os meninos, houve aumento na frequência de indivíduos classificados como “muito bom/excelente” à medida que a idade relativa aumentava. Uma tendência semelhante foi observada entre as meninas. Os achados forneceram evidências do efeito de idade relativa na potência muscular de crianças e adolescentes brasileiros. Esses resultados têm implicações práticas na organização de atividades físicas estruturadas e esportes em diferentes contextos, pois indivíduos nascidos mais cedo podem ter vantagem no desempenho em tarefas que exijam potência muscular. Mais pesquisas são necessárias para explorar os mecanismos subjacentes e intervenções que possam mitigar o efeito de idade relativa e promover oportunidades iguais para todas as crianças e adolescentes nas atividades físicas e esportes. brasileiros 87766 87 766 87.76 1 anos dados kg horizontal respectivamente fraco (fraco razoável bom excelente bom/excelente bomexcelente aumentava contextos 8776 8 76 87.7 877 87.

Abstract This study aimed to examine the relative age effect on muscle power in a large sample of Brazilian children and adolescents. The sample consisted of 87,766 girls and boys aged 7-16 years, data collected in repeated cross-sectional surveillance carried out since 1999. The participants were grouped into four age subgroups within each chronological age based on birthdates. Upper and lower limbs muscle power were assessed using the 2-Kg medicine ball throw and horizontal jump tests, respectively. The normative distribution of physical fitness components was used for classification. The results showed a significant association between relative age and normative classification of muscle power. Among boys, there was a sequential increase in the frequency of individuals classified as “very good/excellent” as the relative age increased. A similar trend was observed among girls. The findings provided evidence of a relative age effect on muscle power in Brazilian children and adolescents. These findings have implications for the organization of structured physical activities and sports, as early-born individuals may have an advantage in performance. Further research is needed to explore the underlying mechanisms and potential interventions to mitigate the relative age effect and promote equal opportunities for all youth in physical activities and sports. adolescents 87766 87 766 87,76 716 7 16 7-1 years crosssectional cross sectional 1999 birthdates 2Kg Kg 2 tests respectively very good/excellent goodexcellent good excellent increased sports earlyborn early born performance 8776 8 76 87,7 71 1 7- 199 877 87, 19

https://doi.org/10.1590/1980-0037.2024v26e98244

How can we reduce maternal mortality due to preeclampsia? The 4P rule preeclampsia P
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Korkes, Henri Augusto

; Cavalli, Ricardo Carvalho

; Oliveira, Leandro Gustavo De

; Ramos, José Geraldo Lopes

; Martins Costa, Sérgio Hofmeister de Almeida

; Sousa, Francisco Lázaro Pereira de

; Vieira da Cunha Filho, Edson

; de Souza Mesquita, Maria Rita

; Dias Corrêa Júnior, Mário

; Pinheiro Fernandes Araújo, Ana Cristina

; Zaconeta, Alberto Carlos Moreno

; Freire, Carlos Henrique Esteves

; Poli de Figueiredo, Carlos Eduardo

; Rocha Filho, Edilberto Alves Pereira da

; Sass, Nelson

; Peraçoli, José Carlos

; Costa, Maria Laura

Revista Brasileira de Ginecologia e Obstetrícia

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2024, Volume 46 elocation e-rbgo43

Resumo: En | Texto: En | PDF: En

Abstract In low and middle-income countries such as Brazil, most maternal deaths are related to hypertensive complications. Preeclampsia is the leading cause of maternal mortality and morbidity. Significant proportion is associated with the following factors: lack of identification of high-risk women, lack of adequate prevention, difficulty in maintaining a high-risk prenatal follow-up, delayed diagnosis, insecurity and low use of magnesium sulphate, delayed pregnancy interruption and lack of postpartum follow-up of these high-risk cases. Four major actions are proposed to minimize this alarming clinical picture and reduce the mortality rates due to preeclampsia, called the "4 P Rule" (Adequate Prevention – Vigilant Prenatal Care – Timely Delivery (Parturition) – Safe Postpartum). From this simple "rule" we can open a range of important processes and reminders that may help in the guidance of preeclampsia management. middleincome middle income Brazil complications morbidity factors highrisk high risk women prevention followup, followup follow up, up diagnosis sulphate cases 4 " Rule Adequate Parturition (Parturition Postpartum. Postpartum . Postpartum) rule "rule management

https://doi.org/10.61622/rbgo/2024rbgo43

Osteoblastoma of the Capitate Bone: Case Report Bone
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Lima, Lucas Gonçalves Dias de

; Castro, Ubiratan Brum de

; Martins, Gustavo Pacheco Ferreira

Revista Brasileira de Ortopedia

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2024, Volume 59 Nº 2 Páginas 327 - 330

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo Os tumores dos ossos do carpo devem ser investigados em quadros clínicos de dor crônica no punho sem trauma prévio. Gânglio intraósseo, encondroma, osteoma osteoide, e, menos comumente, osteoblastoma são possíveis causas de lesões osteolíticas que afetam os ossos carpais. Na maioria dos casos, a apresentação clínica por si só não é suficiente para diferenciar essas lesões. Conhecer características como o aspecto radiológico e histopatológico de cada uma delas é parte fundamental do diagnóstico diferencial. Apresentamos um caso raro de osteoblastoma do osso capitato, e também fazemos uma revisão da literatura sobre o assunto. prévio intraósseo encondroma osteoide comumente carpais casos diferencial capitato assunto

Abstract Carpal bone tumors must be investigated in clinical cases of chronic wrist pain with no previous trauma. Intraosseous ganglion, enchondroma, osteoid osteoma, and, less commonly, osteoblastoma are potential causes of osteolytic lesions affecting the carpal bones. In most cases, the clinical presentation alone is not enough to differentiate such lesions. Knowledge of certain characteristics, including the radiological and histopathological aspects of each of these tumors, is critical in order to make the differential diagnosis. We present a rare case of osteoblastoma of the capitate bone and review the literature on the subject. trauma ganglion enchondroma osteoma commonly bones characteristics diagnosis subject

https://doi.org/10.1055/s-0041-1724084

Digital tools used on the teaching-learning process in geotechnical engineering teachinglearning teaching learning
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Lemos, Carolina Crissafe dos Santos

; Dias, Luiz Otávio Fontes

; Barbosa, Paulo Sérgio de Almeida

; Marques, Eduardo Antonio Gomes

; Ferraz, Roberto Lopes

; Nalon, Gustavo Henrique

Soils and Rocks

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2024, Volume 47 Nº 2 elocation e2024004923

Resumo: En | Texto: En | PDF: En

Abstract This article presents the incorporation of information and communication technologies on the teaching-learning process of geotechnical engineering to improve the quality of education and provide practical knowledge to civil engineering students. The content of this paper is divided into three main modules, which are: Treatment of laboratory tests results, Slope stability and Rock mass stability. For this, some software were used, including 2D limit equilibrium stability analysis, stability analysis of rock wedges and a dynamic mathematics, to obtain and analyze soil shear strength parameters, among others. Furthermore, a digital tool was developed to analyze the results gathered in compaction, one-dimensional consolidation, and direct soil shear tests, in order to clarify the relationship between theoretical concepts and practical results of the tests and analyses and to help students on doubts, in addition to increase their interest and motivation to perform the complete interpretation of the collected data. The activities were conducted in classes of geotechnical disciplines of the undergraduate course in Civil Engineering at the Federal University of Viçosa, aiming to promote active learning and improve teaching quality. Based on the results of an applied feedback questionnaire, it was observed that most students were satisfied with the resources used in the classroom, demonstrating that the implemented digital tools work as a didactic instrument that facilitates learning and comprehension of practical problems, in addition to enabling the resolution of several geotechnical engineering problems much more quickly and efficiently. teachinglearning modules are D mathematics parameters others Furthermore compaction onedimensional one dimensional consolidation doubts data Viçosa questionnaire classroom efficiently

https://doi.org/10.28927/sr.2024.004923

10.

3D implant of copolyamide associated with thermoplastic elastomer (PCTPE) for tracheal repair in rabbits (Oryctolagus cuniculus): preliminary study D PCTPE (PCTPE Oryctolagus cuniculus cuniculus)
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Rein, Ariadne

; Costa, Marcelo Carrijo da

; Montanhin, Gabriel

; Fernandes, Gustavo

; Leite, Marcella Dall’ Agnol

; Carra, Gabriel João Unger

; Vasconcelos, Rosemeri de Oliveira

; Dias, Luís Gustavo Gosuen Gonçalves

; Rocha, Thiago André Salvitti de Sá

; Moraes, Paola Castro

Ciência Animal Brasileira

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2024, Volume 25 elocation 76225E

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo Defeitos de grandes segmentos traqueais podem apresentar sério problema clínico, devido à ausência de substitutos na cirurgia reconstrutiva. Os biomateriais poliméricos estão entre os mais utilizados na medicina. Entretanto, a implantação de um biomaterial desencadeia uma série de eventos biológicos e a biocompatibilidade do material é de extrema importância para a medicina regenerativa. Objetivou-se com este estudo avaliar o uso da copoliamida associada ao elastômero termoplástico (PCTPE) em próteses impressas em 3D para reparação de defeitos parciais da traqueia de coelhos. Foram utilizados 16 coelhos machos da raça Nova Zelândia Branco, submetidos à criação de um defeito parcial de traqueia na região ventral do 4º ao 8º anel traqueal. Os animais foram subdivididos (n=4) de acordo com o momento das eutanásias, programadas com intervalo de sete (G7), quinze (G15), trinta (G30) e sessenta dias (G60). A análise histopatológica por hematoxilina e eosina (HE) revelou que o implante 3D de PCTPE apresentou reação do tipo corpo estranho e a inflamação persistiu até os 60 dias de avaliação. A histoquímica de picrosirius vermelho revelou tendência de maior quantidade de colágeno tipo I nos tempos iniciais de inflamação, enquanto o colágeno tipo III foi predominante nos períodos tardios de avaliação. Pode-se sugerir reação exacerbada e não adequada da interface tecido-material e perpetuação do processo inflamatório. clínico reconstrutiva Entretanto regenerativa Objetivouse Objetivou se (PCTPE D 1 Branco º traqueal n=4 n4 n 4 (n=4 eutanásias G7, G7 G , (G7) G15, G15 (G15) G30 (G30 G60. G60 . (G60) HE (HE 6 avaliação Podese Pode tecidomaterial tecido inflamatório n= (n= (G7 G1 (G15 G3 (G3 G6 (G60 (n (G (G1 (G6

Abstract Large segmental tracheal defects can pose a serious clinical challenge owing to the lack of suitable substitutes for reconstructive surgery. Polymeric biomaterials are widely used in medicine. However, the implantation of biomaterials triggers a series of biological events, and material biocompatibility is of paramount importance in regenerative medicine. The objective of this study was to evaluate the use of a copolyamide associated with thermoplastic elastomer (PCTPE) in 3D-printed prostheses for repairing partial tracheal defects in rabbits. Sixteen male New Zealand White rabbits were used, and partial tracheal defects were created in the ventral region from the 4th to the 8th tracheal ring. The animals were subdivided into groups (n=4) based on the time of euthanasia, scheduled at seven days (G7), 15 days (G15), 30 days (G30), and 60 days (G60). Histopathological analysis with hematoxylin and eosin staining revealed that the 3D implant of PCTPE exhibited a foreign body reaction, and inflammation persisted for up to 60 days. Histochemistry with picrosirius red revealed a tendency for a greater amount of type I collagen to accumulate in the early stages of inflammation, whereas type III collagen was predominant in later evaluation periods. These findings suggest an exacerbated and inadequate tissue-material interface reaction and perpetuation of the inflammatory process. surgery medicine However events (PCTPE 3Dprinted Dprinted printed D th ring n=4 n4 n 4 (n=4 euthanasia G7, G7 G , (G7) 1 G15, G15 (G15) 3 G30, G30 (G30) 6 G60. G60 . (G60) periods tissuematerial tissue process n= (n= (G7 G1 (G15 G3 (G30 G6 (G60 (n (G (G1 (G3 (G6

https://doi.org/10.1590/1809-6891v25e-76225e

11.

Health and lifestyle parameters in peripheral artery disease at two periods of the COVID-19 pandemic: comparison between men and women COVID19 COVID 19 COVID-1 pandemic COVID1 1 COVID-
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Kanegusuku, Hélcio

; Silva, Gustavo Oliveira da

; Braghieri, Heloisa Amaral

; Carvalho, Juliana Ferreira de

; Costa, Renan Massena

; Cucato, Gabriel Grizzo

; Wolosker, Nelson

; Ritti-Dias, Raphael Mendes

; Correia, Marilia Almeida

einstein (São Paulo)

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2024, Volume 22 elocation eAO0345

Resumo: En | Texto: En | PDF: En

ABSTRACT Objective: This study analyzed the impact of sex on self-reported health and lifestyle parameters in peripheral artery disease patients at two periods of the COVID-19 pandemic. Methods: In this longitudinal study, 99 patients with peripheral artery disease (53 men and 46 women) were evaluated during two periods of the COVID-19 pandemic ( i.e ., at onset: May to August 2020, and on follow-up: May to August 2021). Patients were interviewed via telephone, and information regarding lifestyle and health parameters was obtained. Results: At the onset of the COVID-19 pandemic, health and habit parameters were similar between women and men, with 63.0% and 45.3% indicating frequent fatigue, 73.9% and 84.9% reporting increased sitting time, and 23.9% and 39.6% practicing physical activity, respectively. At follow-up, difficulties in physical mobility (women: from 26.1% to 73.9%, p<0.001; men: from 39.6% to 71.7%, p=0.001) and the frequency of hospitalization for reasons other than COVID-19 increased similarly in women and men (women: from 4.3% to 21.7%, p=0.013; men: from 9.4% to 24.5%, p=0.038). The other parameters were similar between the periods. Conclusion: Self-reported physical mobility difficulties and hospitalization frequency increased in women and men with peripheral artery disease. Objective selfreported self reported COVID19 COVID 19 COVID-1 Methods 9 53 (5 4 ie i e . 2020 followup follow up follow-up 2021. 2021 2021) telephone obtained Results 630 63 0 63.0 453 45 3 45.3 fatigue 739 73 73.9 849 84 84.9 time 239 23 23.9 396 39 6 39.6 activity respectively followup, up, (women 261 26 1 26.1 p<0.001 p0001 p 001 717 71 7 71.7% p=0.001 43 4.3 217 21 21.7% p=0.013 p0013 013 94 9.4 245 24 5 24.5% p=0.038. p0038 p=0.038 038 p=0.038) Conclusion Selfreported Self COVID1 COVID- 202 63. 45. 73. 8 84. 2 23. 39. 26. p<0.00 p000 00 71.7 p=0.00 4. 21.7 p=0.01 p001 01 9. 24.5 p003 p=0.03 03 20 p<0.0 p00 71. p=0.0 21. 24. p<0. p0 p=0. p<0 p=0 p< p=

https://doi.org/10.31744/einstein_journal/2024ao0345

12.

Equilíbrio postural e fatores associados ao risco de quedas em idosos com diabetes mellitus tipo 2
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Carlos, Adriana Guedes

; Dias, Vanessa da Nóbrega

; Perracini, Monica Rodrigues

; Doná, Flávia

; Sousa, André Gustavo Pires

; Gazzola, Juliana Maria

Revista Brasileira de Geriatria e Gerontologia

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2024, Volume 27 elocation e230161

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo Objetivo Identificar os fatores clínico-funcionais associados ao risco de quedas, avaliado pelo Mini-BESTest, em idosos com diabetes mellitus tipo 2 (DM2). Método Trata-se de um estudo transversal. Um total de 145 idosos com idade =60 anos foram avaliados por meio das variáveis sociodemográficas (sexo, faixa etária, estado civil, nível de educação e percepção geral da saúde, audição e visão) Mini-BESTest, Mini-Mental State Examination (MMSE), Escala de Depressão Geriátrica (GDS-15) e o teste Timed Up and Go (TUG) (dupla tarefa). Foi utilizado um modelo de regressão logística múltipla. Resultados O domínio de orientação sensorial apresentou a pontuação média mais elevada, seguido pelos domínios estabilidade na marcha, ajustes posturais antecipatórios e respostas posturais. Os fatores associados ao risco de quedas em idosos foram: percepção visual ruim/muito ruim OR 3.40 (1,50-7,72); presença de doenças respiratórias OR 8.00 (1,32-48,46); sensação de tontura OR 2.53 (1,10-5,80); e tempo do teste Timed Up and Go (TUG) (dupla tarefa) igual ou superior a 13,5 segundos OR 3.31 (1,03-10,64). Conclusão Os idosos deste estudo apresentaram um equilíbrio postural comprometido, principalmente no domínio das respostas posturais. O conhecimento dos fatores associados ao risco de quedas em idosos com DM2 permite uma orientação mais eficaz na avaliação, prevenção e intervenção, visando minimizar a ocorrência de quedas e preservar ou otimizar o equilíbrio postural. Diversos fatores influenciaram esse resultado, tais como sobrepeso, baixa atividade física e nível educacional, várias comorbidades, polifarmácia, diagnóstico de DM2 por mais de dez anos, percepção negativa da saúde geral e da visão, e sintomas depressivos. clínicofuncionais clínico funcionais MiniBESTest, MiniBESTest Mini BESTest, BESTest Mini-BESTest DM2. DM . (DM2) Tratase Trata se transversal 14 60 =6 sexo, sexo (sexo etária civil visão MiniMental Mental MMSE, MMSE , (MMSE) GDS15 GDS 15 (GDS-15 TUG (TUG dupla tarefa. tarefa múltipla elevada marcha ruimmuito muito 340 3 40 3.4 1,507,72 150772 1,50 7,72 1 50 7 72 (1,50-7,72) 800 8 00 8.0 1,3248,46 1324846 1,32 48,46 32 48 46 (1,32-48,46) 253 53 2.5 1,105,80 110580 1,10 5,80 10 5 80 (1,10-5,80) 135 13 13, 331 31 3.3 1,0310,64. 1031064 1,03 10,64 03 64 (1,03-10,64) comprometido avaliação intervenção resultado sobrepeso educacional comorbidades polifarmácia depressivos (DM2 6 = (MMSE GDS1 (GDS-1 34 4 3. 507 1,507,7 15077 150 1,5 772 7,7 (1,50-7,72 0 8. 3248 1,3248,4 132484 132 1,3 4846 48,4 (1,32-48,46 25 2. 105 1,105,8 11058 110 1,1 580 5,8 (1,10-5,80 33 0310 1,0310,64 103106 103 1,0 1064 10,6 (1,03-10,64 (DM (GDS- 1,507, 1507 1, 77 7, (1,50-7,7 324 1,3248, 13248 484 48, (1,32-48,4 1,105, 1105 11 58 5, (1,10-5,8 031 1,0310,6 10310 106 10, (1,03-10,6 (GDS 1,507 (1,50-7, 1,3248 1324 (1,32-48, 1,105 (1,10-5, 1,0310, 1031 (1,03-10, (1,50-7 1,324 (1,32-48 (1,10-5 1,0310 (1,03-10 (1,50- (1,32-4 (1,10- 1,031 (1,03-1 (1,50 (1,32- (1,10 (1,03- (1,5 (1,32 (1,1 (1,03 (1, (1,3 (1,0 (1 (

Abstract Objective Identify clinical-functional factors associated to the risk of falls, assessed by Mini-BESTest in older adults with type 2 diabetes mellitus (T2DM). Method This cross-sectional study. A total of 145 older adults aged ≥60 years were evaluated through sociodemographic variables (sex, age group, married, education level, general health status hearing and vision), Mini-BESTest, Mini-Mental State Examination (MMSE), Geriatric Depression Scale (GDS-15) and dual-task Timed Up and Go Test (TUG) Multiple logistic regression model was used. Results The sensory orientation domain presented the highest average score, followed by the gait stability, anticipatory postural adjustments and postural responses domains. Factors associated to the risk of falls in older adults are: poor/very poor visual perception OR 3.40 (1.50-7.72); have respiratory diseases OR 8.00 (1.32-48.46); feeling dizzy OR 2.53 (1.10-5.80); and TUGT (dual task) time equal to or greater than 13.5 seconds OR 3.31 (1.03-10.64). Conclusion Older adults in this study presented impaired postural balance, mainly in the postural responses domain. The knowledge of the factors associated with the risk of falls in older adults with T2DM allows for better guidance in prevention, assessment and intervention, in order to minimize the occurrence of falls and maintain or optimize postural balance. Several factors influenced this outcome, such as overweight, low physical activity and education, several comorbidities, polypharmacy, T2DM diagnosis for more than ten years, negative perception of general health and vision, and depressive symptoms. clinicalfunctional clinical functional MiniBESTest Mini BESTest T2DM. TDM . T DM (T2DM) crosssectional cross sectional 14 60 ≥6 sex, sex (sex group married level vision , vision) MiniBESTest, BESTest, MiniMental Mental MMSE, MMSE (MMSE) GDS15 GDS 15 (GDS-15 dualtask dual task TUG (TUG used score stability domains are poorvery very 340 3 40 3.4 1.507.72 150772 1.50 7.72 1 50 7 72 (1.50-7.72) 800 8 00 8.0 1.3248.46 1324846 1.32 48.46 32 48 46 (1.32-48.46) 253 53 2.5 1.105.80 110580 1.10 5.80 10 5 80 (1.10-5.80) 135 13 13. 331 31 3.3 1.0310.64. 1031064 1.03 10.64 03 64 (1.03-10.64) balance prevention intervention outcome overweight comorbidities polypharmacy symptoms (T2DM 6 ≥ (MMSE GDS1 (GDS-1 34 4 3. 507 1.507.7 15077 150 1.5 772 7.7 (1.50-7.72 0 8. 3248 1.3248.4 132484 132 1.3 4846 48.4 (1.32-48.46 25 2. 105 1.105.8 11058 110 1.1 580 5.8 (1.10-5.80 33 0310 1.0310.64 103106 103 1.0 1064 10.6 (1.03-10.64 (GDS- 1.507. 1507 1. 77 7. (1.50-7.7 324 1.3248. 13248 484 48. (1.32-48.4 1.105. 1105 11 58 5. (1.10-5.8 031 1.0310.6 10310 106 10. (1.03-10.6 (GDS 1.507 (1.50-7. 1.3248 1324 (1.32-48. 1.105 (1.10-5. 1.0310. 1031 (1.03-10. (1.50-7 1.324 (1.32-48 (1.10-5 1.0310 (1.03-10 (1.50- (1.32-4 (1.10- 1.031 (1.03-1 (1.50 (1.32- (1.10 (1.03- (1.5 (1.32 (1.1 (1.03 (1. (1.3 (1.0 (1 (

https://doi.org/10.1590/1981-22562023026.230161.pt

13.

Influence of Rail Metallurgy and Welding Parameterization on the Quality of Flash Butt Welds Done with Mobile Equipment
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Alves, Luiz Henrique Dias

; Pereira, Henrique Boschetti

; Echeverri, Edwan Anderson Ariza

; Rezende, Iran José

; Souza, Ricardo

; Flores, Wagner Duarte

; Tressia, Gustavo

; Goldenstein, Hélio

Materials Research

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2024, Volume 27 elocation e20230566

Resumo: En | Texto: En | PDF: En

The aim of this study was to assess the impact of rail metallurgy, focusing on segregations and chemical composition, and welding parameterization on the quality and susceptibility of welds to defects and failures induced by mobile flash butt welding (FBW). Ten welds were performed using two different welding programs, with varying heat input, on premium rails sourced from the same batch. The welds underwent full metallurgical characterization of the weld and HAZ, including hardness profile, mechanical testing, and micrographic analysis of the head, web, and foot regions. The results showed that both the HAZ dimensions and the hardness profile are influenced by weld parameterization. All welds fabricated by the lower heat input program, small islands of martensite and retained austenite (MA) were observed only in the foot region, close to the weld line. From the higher heat input program, only one weld showed islands of MA. Localized chemical analysis indicated that the formation of these islands is linked to microsegregation, especially of Mn and Cr present in the rail. metallurgy composition FBW. FBW . (FBW) programs batch testing head web regions program MA (MA region line microsegregation (FBW

https://doi.org/10.1590/1980-5373-mr-2023-0566

14.

Metástases Tireoidianas de Carcinoma Hepatocelular após Transplante Hepático
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Viana, Danilo Dias Avancini

; Magalhães, Angel Evangelista Barroso

; Silva, Dayane Laura da

; Teixeira, Larissa Peixoto

; Dias, Larissa Ponte

; Lima, Clebia Azevedo de

; Hyppolito, Elodie Bomfim

; Costa, Paulo Everton Garcia

; Coelho, Gustavo Rêgo

; Garcia, José Huygens Parente

Brazilian Journal of Transplantation

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2024, Volume 27 elocation e4024

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

ABSTRACT Hepatocellular carcinoma (HCC) patients with metastases to the thyroid are extremely rare. A patient who underwent liver transplantation for HCC recurrence had metastatic thyroid recurrence detected 4 years later. A literature review identified six documented cases, analyzing relevant data on HCC with thyroid metastasis following liver transplantation. There is a prevalence of hepatitis B virus (HBV) and hepatitis C virus (HCV) as etiologies of liver disease (83.3%), with alpha-fetoprotein (AFP) levels elevated in five cases. Additionally, the time between the diagnosis of HCC and thyroid metastasis was within 3 years. The patient remains clinically stable in outpatient follow-up, with an 8-month current survival after total thyroidectomy. (HCC rare later cases HBV (HBV HCV (HCV 83.3%, 833 83.3% , 83 (83.3%) alphafetoprotein alpha fetoprotein AFP (AFP Additionally followup, followup follow up, up follow-up 8month month 8 thyroidectomy 83.3 (83.3% 83. (83.3 (83. (83 (8 (

RESUMO Pacientes com metástase tireoidiana de carcinoma hepatocelular (CHC) são extremamente raros. Um paciente que realizou transplante hepático devido à recorrência de CHC apresentou metástase tireoidiana detectada 4 anos depois. A revisão de literatura identificou seis casos documentados, analisando informações relevantes sobre CHC com metástase tireoidiana após transplante de fígado. Verificou-se a prevalência do vírus da hepatite B (VHB) e da hepatite C (VHC) como etiologias da doença hepática (83,3%), com níveis elevados de alfafetoproteína (AFP) em cinco casos. Além disso, o tempo entre o diagnóstico de CHC e a metástase tireoidiana foi inferior a 3 anos. O paciente permanece clinicamente estável no acompanhamento ambulatorial, com sobrevida atual de 8 meses após tireoidectomia total. (CHC raros depois documentados fígado Verificouse Verificou se VHB (VHB VHC (VHC 83,3%, 833 83,3% , 83 (83,3%) AFP (AFP disso ambulatorial total 83,3 (83,3% 83, (83,3 (83, (83 (8 (

https://doi.org/10.53855/bjt.v27i1.584_port

15.

Use of insect repellent as personal protection among women of childbearing age in an arbovirus endemic area in Northeastern Brazil
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Dias, Livia Karla Sales

; Sanhueza-Sanzana, Carlos

; Pinheiro Júnior, Francisco Marto Leal

; Martins, Adriano Ferreira

; Correia, Francisco Gustavo Silveira

; de Aguiar, Italo Wesley Oliveira

; Ferreira, Nayane Cavalcante

; Stolow, Jeni

; Rutherford, George

; Teixeira, Maria Gloria

; Pires Neto, Roberto da Justa

; de Almeida, Rosa Livia Freitas

; Coelho, Ivo Castelo Branco

; Frota, Cristiane Cunha

; Kendall, Carl

; Kerr, Ligia Regina Franco Sansigolo

Revista Brasileira de Epidemiologia

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2024, Volume 27 elocation e240025

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RESUMO Objetivo: Analisar os fatores associados ao uso de repelente individual por mulheres em idade fértil residentes em área endêmicas para arboviroses em Fortaleza, Brasil. Métodos: Coorte realizada entre 2018 e 2019, com mulheres entre 15 e 39 anos, moradoras em Fortaleza, Ceará, Brasil. Participaram 1.173 mulheres, usuárias de quatro unidades primárias de saúde do município. O desfecho foi categorizado em: uso continuado, uso descontinuado e não uso de repelente. Realizada análise de regressão logística multinominal norteada por modelo hierárquico, com apresentação dos respectivos odds ratio (OR) e intervalos de confiança de 95% (IC95%). As variáveis independentes incluem: dados socioeconômicos e demográficos, características ambientais e sanitárias, conhecimento sobre o repelente e aspectos comportamentais e relacionados à gravidez. Resultados: Somente 28% das participantes referiram o uso de repelente durante as duas ondas da coorte. Mulheres com escolaridade superior (OR=2,55; IC95% 1,44–4,51); com emprego (OR=1,51; IC95% 1,12–2,03); que receberam orientações por profissionais da saúde (OR=1,74; IC95% 1,28–2,36) e pela mídia (OR=1,43; IC95% 1,01–2,02); que intensificaram os cuidados contra o mosquito na epidemia (OR=3,64; IC95% 2,29–5,78); estavam grávidas entre 2016 e 2019 (OR=2,80; IC95% 1,83–4,30) tiveram as chances aumentadas para uso continuado de repelente. Conclusões: O uso de repelente entre mulheres em idade fértil mostrou-se associado a um maior nível de escolaridade, ao emprego, às orientações sobre repelente fornecidas por profissionais de saúde e pela mídia, às mudanças comportamentais de cuidado contra o mosquito durante a epidemia da Zika e à gravidez quando ocorrida a partir do início do período epidêmico. Objetivo Fortaleza Brasil Métodos 201 1 3 anos Ceará 1173 173 1.17 município hierárquico OR (OR 95 IC95%. IC95 IC . (IC95%) incluem demográficos sanitárias Resultados 28 coorte OR=2,55 OR255 2 55 (OR=2,55 1,44–4,51 144451 44 4 51 1,44–4,51) OR=1,51 OR151 (OR=1,51 1,12–2,03 112203 12 03 1,12–2,03) OR=1,74 OR174 74 (OR=1,74 1,28–2,36 128236 36 OR=1,43 OR143 43 (OR=1,43 1,01–2,02 101202 01 02 1,01–2,02) OR=3,64 OR364 64 (OR=3,64 2,29–5,78 229578 29 5 78 2,29–5,78) OR=2,80 OR280 80 (OR=2,80 1,83–4,30 183430 83 30 Conclusões mostrouse mostrou se epidêmico 20 117 17 1.1 9 IC9 (IC95% OR=2,5 OR25 (OR=2,5 1,44–4,5 14445 OR=1,5 OR15 (OR=1,5 1,12–2,0 11220 0 OR=1,7 OR17 7 (OR=1,7 1,28–2,3 12823 OR=1,4 OR14 (OR=1,4 1,01–2,0 10120 OR=3,6 OR36 6 (OR=3,6 2,29–5,7 22957 OR=2,8 OR28 8 (OR=2,8 1,83–4,3 18343 11 1. (IC95 OR=2, OR2 (OR=2, 1,44–4, 1444 OR=1, OR1 (OR=1, 1,12–2, 1122 1,28–2, 1282 1,01–2, 1012 OR=3, OR3 (OR=3, 2,29–5, 2295 1,83–4, 1834 (IC9 OR=2 (OR=2 1,44–4 144 OR=1 (OR=1 1,12–2 112 1,28–2 128 1,01–2 101 OR=3 (OR=3 2,29–5 229 1,83–4 183 (IC OR= (OR= 1,44– 14 1,12– 1,28– 1,01– 10 2,29– 22 1,83– 18 1,44 1,12 1,28 1,01 2,29 1,83 1,4 1,1 1,2 1,0 2,2 1,8 1, 2,

ABSTRACT Objective: To analyze the factors associated with the individual use of insect repellent by women of childbearing age living in area endemic for arboviruses in Fortaleza, Brazil. Methods: This is a cohort study carried out between 2018 and 2019 with women aged between 15 and 39 years in Fortaleza, state of Ceará, Brazil. A total of 1,173 women users of one of the four selected primary health care units participated in the study. The outcome was divided into: continued use, discontinued use, and nonuse of insect repellent. Crude and adjusted multinominal logistic regression analysis was carried out guided by a hierarchical model, with presentation of the respective odds ratio (OR) and 95% confidence intervals (95%CI). The independent variables include: socioeconomic and demographic data, environmental and sanitary characteristics, knowledge of the insect repellent, and behavioral and pregnancy-related aspects. Results: Only 28% of the participants reported using insect repellent during the two waves of the cohort. Women with higher education (OR=2.55; 95%CI 1.44–4.51); who are employed (OR=1.51; 95%CI 1.12–2.03); who received guidance from healthcare professionals (OR=1.74; 95%CI 1.28–2.36) and the media (OR=1.43; 95%CI 1.01–2.02); who intensified precautions against mosquitoes during the epidemic (OR=3.64; 95%CI 2.29–5.78); and who were pregnant between 2016 and 2019 (OR=2.80; 95%CI 1.83–4.30) had increased odds for continued use of insect repellent. Conclusion: The use of insect repellent among women of childbearing age was associated with a higher level of education, employment, guidance on insect repellent provided by healthcare professionals and the media, behavioral changes to protect against mosquitoes during the Zika virus epidemic, and pregnancy when occurring as of the beginning of the epidemic period. Objective Fortaleza Brazil Methods 201 1 3 Ceará 1173 173 1,17 into model OR (OR 95 95%CI. 95CI CI . (95%CI) include data characteristics pregnancyrelated related aspects Results 28 OR=2.55 OR255 2 55 (OR=2.55 1.44–4.51 144451 44 4 51 1.44–4.51) OR=1.51 OR151 (OR=1.51 1.12–2.03 112203 12 03 1.12–2.03) OR=1.74 OR174 74 (OR=1.74 1.28–2.36 128236 36 OR=1.43 OR143 43 (OR=1.43 1.01–2.02 101202 01 02 1.01–2.02) OR=3.64 OR364 64 (OR=3.64 2.29–5.78 229578 29 5 78 2.29–5.78) OR=2.80 OR280 80 (OR=2.80 1.83–4.30 183430 83 30 Conclusion employment period 20 117 17 1,1 9 (95%CI OR=2.5 OR25 (OR=2.5 1.44–4.5 14445 OR=1.5 OR15 (OR=1.5 1.12–2.0 11220 0 OR=1.7 OR17 7 (OR=1.7 1.28–2.3 12823 OR=1.4 OR14 (OR=1.4 1.01–2.0 10120 OR=3.6 OR36 6 (OR=3.6 2.29–5.7 22957 OR=2.8 OR28 8 (OR=2.8 1.83–4.3 18343 11 1, OR=2. OR2 (OR=2. 1.44–4. 1444 OR=1. OR1 (OR=1. 1.12–2. 1122 1.28–2. 1282 1.01–2. 1012 OR=3. OR3 (OR=3. 2.29–5. 2295 1.83–4. 1834 OR=2 (OR=2 1.44–4 144 OR=1 (OR=1 1.12–2 112 1.28–2 128 1.01–2 101 OR=3 (OR=3 2.29–5 229 1.83–4 183 OR= (OR= 1.44– 14 1.12– 1.28– 1.01– 10 2.29– 22 1.83– 18 1.44 1.12 1.28 1.01 2.29 1.83 1.4 1.1 1.2 1.0 2.2 1.8 1. 2.

https://doi.org/10.1590/1980-549720240025

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