A gravidez na adolescência é um desafio de saúde pública no Brasil, com uma taxa de fecundidade de 43,6 nascimentos por mil meninas de 15 a 19 anos em 2022. Este estudo investigou as desigualdades nas taxas de fecundidade adolescente (TFA) nos municípios brasileiros, utilizando dados do Sistema de Informações sobre Nascidos Vivos (SINASC) e do Censo Demográfico de 2022. A análise considerou nascimentos entre 2020 e 2022, excluindo municípios com menos de 50 nascimentos nos três anos. As TFAs municipais foram comparadas com a taxa média de países classificados por nível de renda (alta, média-alta, média-baixa e baixa renda) e descritas conforme o Índice Brasileiro de Privação e o tamanho populacional. As desigualdades dentro de cada região geográfica foram avaliadas usando a diferença absoluta média em relação à média regional e a amplitude. Foram observadas grandes disparidades nas TFAs entre as regiões, com o Norte e Nordeste apresentando as maiores taxas, e o Sul e Sudeste, as menores. O Centro-Oeste teve valores intermediários. As desigualdades entre os municípios foram evidenciadas por gráficos e índices, com uma pequena parcela de municípios da região Norte mostrando TFA excepcionalmente alta. Foi identificada uma forte associação entre vulnerabilidade social e gravidez precoce, com municípios em situações de maior privação apresentando taxas de fecundidade marcadamente mais altas. Os resultados destacam a necessidade de políticas públicas que abordem os determinantes contextuais subjacentes para reduzir as taxas de fecundidade entre adolescentes no Brasil. Versão em Português: https://doi.org/10.1590/SciELOPreprints.11537

Adolescent childbearing is a major public health challenge in Brazil, with a fertility rate of 43.6 births per thousand girls aged 15-19 years in 2022. This study investigated inequalities in adolescent fertility rates (AFR) across Brazilian municipalities, utilizing data from the National Live Births Information System (SINASC) and the 2022 Demographic Census. Analyses included births between 2020 and 2022, excluding municipalities with fewer than 50 births in the 3 years. Municipal AFRs were compared with the average rate in countries classified by income level (high, upper-middle, lower-middle, and low income) and described according to the Brazilian Deprivation Index and population size. Inequalities within each geographic region were assessed using the mean absolute difference to the regional mean and range. Substantial disparities in AFR across regions were found, with the North and Northeast exhibiting the highest estimates, while the South and Southeast showed comparatively lower rates. The Midwest presented intermediate values. We found vast inequalities between municipalities, revealed by graphs and summary measures. A small proportion of municipalities, concentrated in the North region, experience exceptionally high AFR. A strong association between social vulnerability and early childbearing was also identified. Municipalities with higher levels of deprivation had markedly higher AFR, underscoring the influence of broader socio-economic factors on adolescent fertility. The results emphasize the need for targeted interventions and policies that address these underlying contextual determinants to reduce fertility rates among girls in Brazil effectively. Versão em Português: https://doi.org/10.1590/SciELOPreprints.11537

Adolescent childbearing is a major public health challenge in Brazil, with a fertility rate of 43.6 births per thousand girls aged 15-19 years in 2022. This study investigated inequalities in adolescent fertility rates (AFR) across Brazilian municipalities, utilizing data from the National Live Births Information System (SINASC) and the 2022 Demographic Census. Analyses included births between 2020 and 2022, excluding municipalities with fewer than 50 births in the 3 years. Municipal AFRs were compared with the average rate in countries classified by income level (high, upper-middle, lower-middle, and low income) and described according to the Brazilian Deprivation Index and population size. Inequalities within each geographic region were assessed using the mean absolute difference to the regional mean and range. Substantial disparities in AFR across regions were found, with the North and Northeast exhibiting the highest estimates, while the South and Southeast showed comparatively lower rates. The Midwest presented intermediate values. We found vast inequalities between municipalities, revealed by graphs and summary measures. A small proportion of municipalities, concentrated in the North region, experience exceptionally high AFR. A strong association between social vulnerability and early childbearing was also identified. Municipalities with higher levels of deprivation had markedly higher AFR, underscoring the influence of broader socio-economic factors on adolescent fertility. The results emphasize the need for targeted interventions and policies that address these underlying contextual determinants to reduce fertility rates among girls in Brazil effectively. English version: https://doi.org/10.1590/SciELOPreprints.11534

A gravidez na adolescência é um desafio de saúde pública no Brasil, com uma taxa de fecundidade de 43,6 nascimentos por mil meninas de 15 a 19 anos em 2022. Este estudo investigou as desigualdades nas taxas de fecundidade adolescente (TFA) nos municípios brasileiros, utilizando dados do Sistema de Informações sobre Nascidos Vivos (SINASC) e do Censo Demográfico de 2022. A análise considerou nascimentos entre 2020 e 2022, excluindo municípios com menos de 50 nascimentos nos três anos. As TFAs municipais foram comparadas com a taxa média de países classificados por nível de renda (alta, média-alta, média-baixa e baixa renda) e descritas conforme o Índice Brasileiro de Privação e o tamanho populacional. As desigualdades dentro de cada região geográfica foram avaliadas usando a diferença absoluta média em relação à média regional e a amplitude. Foram observadas grandes disparidades nas TFAs entre as regiões, com o Norte e Nordeste apresentando as maiores taxas, e o Sul e Sudeste, as menores. O Centro-Oeste teve valores intermediários. As desigualdades entre os municípios foram evidenciadas por gráficos e índices, com uma pequena parcela de municípios da região Norte mostrando TFA excepcionalmente alta. Foi identificada uma forte associação entre vulnerabilidade social e gravidez precoce, com municípios em situações de maior privação apresentando taxas de fecundidade marcadamente mais altas. Os resultados destacam a necessidade de políticas públicas que abordem os determinantes contextuais subjacentes para reduzir as taxas de fecundidade entre adolescentes no Brasil. English version: https://doi.org/10.1590/SciELOPreprints.11534

Resumo Investigamos o início do pré-natal em adolescentes brasileiras para subsidiar a discussão nacional sobre o limite de idade gestacional para o aborto legal. Com dados do Sistema de Informação sobre Nascidos Vivos (SINASC) 2020-2022 correlacionamos o início oportuno do pré-natal (primeiro trimestre da gestação) com a idade da adolescente, região, raça/cor e escolaridade; 11.607 partos anuais resultam de estupro de vulnerável. O início oportuno foi de 70,2% para todas as adolescentes (<20 anos), mas de apenas 55,6% para aquelas abaixo de 13 anos; 14,1% das adolescentes iniciaram o pré-natal com 22 semanas ou mais de gestação (28,3% entre <13 anos). O início oportuno foi menor na região Norte, entre meninas indígenas e com baixa escolaridade. Demoras no reconhecimento da gestação e na comunicação para a família contribuem para o início tardio do pré-natal e para a decisão de abortar. A proposta de limite do prazo para abortos legais irá atingir principalmente as adolescentes mais vulneráveis em termos socioeconômicos e raciais.

Resumen Investigamos el inicio oportuno de la atención prenatal entre las adolescentes brasileñas para apoyar la discusión nacional sobre el límite de edad gestacional para el aborto legal. Con datos del Sistema de Información sobre Nacidos Vivos (SINASC) 2020-2022, correlacionamos el inicio oportuno del cuidado prenatal (primer trimestre del embarazo) con la edad de la adolescente, la región, la etnia/color de piel y el nivel de escolaridad; 11.607 nacimientos anuales resultan de violaciones vulnerables. El inicio oportuno fue del 70,2% para todas las adolescentes (<20 años), pero solo del 55,6% para aquellas menores de 13 años; el 14,1% de las adolescentes comenzaron el cuidado prenatal a las 22 semanas o más de embarazo (28,3% entre las menores de 13 años). El inicio oportuno fue menor en la región Norte, entre las niñas indígenas y las de baja escolaridad. Los retrasos en el reconocimiento del embarazo y en la comunicación con la familia contribuyen al inicio tardío del cuidado prenatal y a la decisión de abortar. La propuesta de límite de tiempo para los abortos legales afectará principalmente a las adolescentes más vulnerables en términos socioeconómicos y raciales.

Abstract We investigated the timely initiation of antenatal care among Brazilian adolescents to support the national discussion on the gestational age limit for legal abortion. Using data from the Live Births Information System (SINASC) 2020-2022, we correlated the timely antenatal care (first quarter of pregnancy) with the adolescent’s age, region, ethnicity/skin color, and schooling level; 11,607 annual births result from vulnerable rape. The timely initiation of antenatal care was 70.2% for all adolescents (<20 years), but only 55.6% for those under 13 years old; 14.1% of adolescents started antenatal care at 22 weeks or more of gestation (28.3% among those <13 years old). Timely initiation was lower in the North region, among Indigenous girls, and those with low education. Delays in recognizing the pregnancy and communicating with the family contribute to the late start of antenatal care and the decision to abort. The proposed legal abortion time limit will mainly impact the most vulnerable adolescents in terms of socioeconomic and racial factors.

ABSTRACT Purpose: This study aimed to evaluate the therapeutic effect of an ethanol extract of Ocimum basilicum L. (EEOb) aerial parts against Ehrlich’s experimental tumor (EET) in mice. Methods: Swiss mice were divided into two groups (control and treated; n = 6). On day 21, all mice were inoculated subcutaneously with 2 × 106 (0.05 mL) EET cells in the left paw for solid tumor development. This study lasted 28 days. Treatment began 24 hours after inoculation with EET. Measurements of dorsoplantar thickness were used to assess tumor growth. The paw pad was collected for histopathological analysis and stained using the argyrophilic nucleolar organizing regions (AgNOR) technique and immunohistochemistry for proliferating cell nuclear antigen, Bcl-2 and Bax. Results: The treatment of animals with EEOb at 100 mg/kg intraperitoneally was able to reduce the growth (Control = 3.7 ± 0.1 mm vs. EEOb = 5.7 ± 0.2 mm) and the number of AgNORs of solid Ehrlich tumor. The antitumor effect of EEOb was associated with the induction of apoptosis of tumoral cell, as suggested by the reduction of the content of Bcl-2 induced by extract. Conclusions: The study demonstrated that daily administration of EEOb is able to reduce the growth of EET by induce apoptosis of tumoral cells. Purpose L (EEOb Ehrlichs s (EET Methods control treated 6. 6 . 6) 21 10 0.05 005 0 05 (0.0 mL development days AgNOR (AgNOR antigen Bcl2 Bcl Bcl- Bax Results mgkg mg kg Control 37 3 7 3. 01 1 0. vs 57 5 5. 02 Conclusions 0.0 00 (0. (0 (

ABSTRACT OBJECTIVE To describe two low-burden diet quality scores and evaluate their performance in reflecting the dietary share of the least and most processed foods defined within the Nova food system classification. METHODS This cross-sectional study included data from the NutriNet-Brasil cohort. Participants answered the Nova24hScreener, a 3-minute self-administered questionnaire measuring the consumption of a set of foods on the day before. Food items included in this tool belong to two main groups of the Nova classification: unprocessed or minimally processed whole plant foods (WPF, 33 items) and ultra-processed foods (UPF, 23 items). Two scores were obtained by summing the number of items checked: the Nova-WPF and the Nova-UPF. We compared the scores, respectively, with the dietary intake (% of total energy) of all unprocessed or minimally processed whole plant foods and all ultra-processed foods obtained from a full self-administered web-based 24-hour recall performed on the same day. RESULTS The approximate quintiles of each score had a direct and linear relationship with the corresponding % of energy intake (p-value for linear trend < 0.001). We found a substantial agreement between the intervals of each score and the corresponding % of energy intake (Nova-WPF score: Prevalence-Adjusted and Bias-Adjusted Kappa (PABAK) 0.72, 95%CI 0.64–0.81; Nova-UPF score: PABAK 0.79, 95%CI 0.69–0.88). CONCLUSIONS These two scores performed well against the dietary share of unprocessed or minimally processed whole plant foods and ultra-processed foods in Brazil and can be used to evaluate and monitor diet quality. lowburden low burden classification crosssectional cross sectional NutriNetBrasil NutriNet Brasil cohort Nova24hScreener NovahScreener hScreener 3minute minute 3 selfadministered self administered before WPF, WPF (WPF ultraprocessed ultra UPF, UPF (UPF 2 items. . checked NovaWPF NovaUPF. NovaUPF UPF. respectively ( webbased web based 24hour hour 24 pvalue p value 0.001. 0001 0.001 0 001 0.001) PrevalenceAdjusted Prevalence Adjusted BiasAdjusted Bias (PABAK 072 72 0.72 95CI CI 95 0.64–0.81 064081 64 81 079 79 0.79 0.69–0.88. 069088 0.69–0.88 69 88 0.69–0.88) 000 0.00 00 07 7 0.7 9 0.64–0.8 06408 6 8 06908 0.69–0.8 0.0 0. 0.64–0. 0640 0690 0.69–0. 0.64–0 064 069 0.69–0 0.64– 06 0.69– 0.64 0.69 0.6

Aim The present study aimed to investigate if cannabis use can be associated with gingival bleeding and caries experience among Brazilian students. Methods A cross-sectional study was performed in 2016 with first-semester university students in Pelotas. Data was collected via a self-administered questionnaire. Self-reported gingival bleeding and caries experienced were collected. Cannabis use was assessed using a modified version of the Alcohol, Smoking, and Substance Involvement Screening Test (ASSIST). We define cannabis users as individuals who report using cannabis at least once a month. A Poisson regression model with robust variance was used to analyze the data. Results A total of 2,058 (64.5% of eligible students) students were assessed. The prevalence of caries experience was 68.2% and gingival bleeding was 50.8%. The prevalence of cannabis use was 11.7%. After controlling (sex, skin color, age, family income, depressive symptoms, oral health self-perception tobacco use), individuals who use cannabis present a prevalence of gingival bleeding 2.51 (CI95%[1.42–4;53]) higher than individuals who did not use cannabis. The association was maintained even when the individuals who used tobacco were excluded from the sample (PR=2.24, CI95%[1.16 – 4.31]). Cannabis use did not show an association with the experience of dental caries in both crude (PR 0.91 CI95%[0.82 – 1.01]) and adjusted models (PR 0.93 CI 95%[0.83 – 1.05]). Conclusion Cannabis use was associated with the presence of gingival bleeding among the students of a public university in the south of Brazil. However, the experience of dental caries did not present an association with cannabis use. crosssectional cross sectional 201 firstsemester first semester Pelotas selfadministered self administered questionnaire Selfreported Self reported Alcohol Smoking ASSIST. ASSIST . (ASSIST) month data 2058 2 058 2,05 64.5% 645 64 5 (64.5 682 68 68.2 508 50 8 50.8% 117 11 7 11.7% sex, sex (sex color age income symptoms selfperception perception use, , use) 251 51 2.5 CI95%1.42–453 CI95142453 CI95% 1.42–4 53 CI95 1 42 4 (CI95%[1.42–4;53] PR=2.24, PR224 PR 24 (PR=2.24 CI95%1.16 CI95116 1.16 16 CI95%[1.1 4.31. 431 4.31 31 4.31]) 091 0 91 0.9 CI95%0.82 CI95082 0.82 82 CI95%[0.8 1.01 101 01 1.01] 093 93 95%0.83 95083 95% 0.83 95 83 95%[0.8 1.05. 105 1.05 05 1.05]) Brazil However 20 (ASSIST 205 2,0 64.5 6 (64. 68. 50.8 11.7 25 2. 453 CI95%1.42–45 CI9514245 1424 1.42– CI9 (CI95%[1.42–4;53 PR=2.24 PR22 (PR=2.2 CI95%1.1 CI9511 116 1.1 CI95%[1. 43 4.3 3 4.31] 09 9 0. CI95%0.8 CI9508 082 0.8 CI95%[0. 1.0 10 95%0.8 9508 083 95%[0. 1.05] 2, 64. (64 50. 11. 45 CI95%1.42–4 CI951424 142 1.42 (CI95%[1.42–4;5 PR=2.2 PR2 (PR=2. CI95%1. CI951 1. CI95%[1 4. CI95%0. CI950 08 CI95%[0 95%0. 950 95%[0 (6 CI95%1.42– CI95142 14 1.4 (CI95%[1.42–4; PR=2. (PR=2 CI95%1 CI95%[ CI95%0 95%0 95%[ ( CI95%1.42 CI9514 (CI95%[1.42–4 PR=2 (PR= CI95%1.4 (CI95%[1.42– PR= (CI95%[1.42 (CI95%[1.4 (CI95%[1. (CI95%[1 (CI95%[ (CI95% (CI95 (CI9 (CI

Abstract The present study aimed to investigate the contextual inequalities of specialized public dental care (SPDC) in Brazil. The outcome was the trajectory of dental specialized production in municipalities with SPDC (from 2015 to 2017) obtained by group-based trajectory modeling. A Poisson regression model was used to analyze the factors associated with the high trajectory of SPDC production. The inequality indicators for SPDC production were the slope index and the concentration index according to contextual factors. The study included 954 SPDC units distributed across 893 municipalities. Among the municipalities evaluated, 62.9% had a low trajectory of SPDC. Large-sized municipalities had the highest production (IRR = 2.84, 95%CI: 1.94–4.14) and the southern region had the lowest production (IRR = 0.73, 95%CI: 0.58–0.92). Municipalities presenting a very high human development index (HDI) showed the greatest SPDC production (IRR = 3.34, 95%CI: 1.09–10.24), as well as municipalities with the highest tertile of schooling rate (IRR = 1.23, 95%CI: 1.00–1.50). The absolute inequality was 52.1 percentage points for the average monthly wage (p < 0.001), 61.0 percentage points for the HDI (p < 0.001), -22.1 for infant mortality rate (p <0.001), and 14.8 for the schooling rate (p = 0.012). Thus, there are contextual inequalities in the Brazilian SPDC. Higher scores for social indicators were associated with better SPDC performance. (SPDC Brazil from 201 2017 groupbased group based modeling 95 89 evaluated 629 62 9 62.9 Largesized Large sized IRR 284 2 84 2.84 95%CI 95CI CI 1.94–4.14 194414 1 94 4 14 073 0 73 0.73 0.58–0.92. 058092 0.58–0.92 . 58 92 0.58–0.92) (HDI 334 3 34 3.34 1.09–10.24, 1091024 1.09–10.24 , 09 10 24 1.09–10.24) 123 23 1.23 1.00–1.50. 100150 1.00–1.50 00 50 1.00–1.50) 521 52 52. p 0.001, 0001 0.001 001 0.001) 610 61 61. 22.1 221 22 -22. <0.001, <0.001 <0.001) 148 8 14. 0.012. 0012 0.012 012 0.012) Thus performance 20 6 62. 28 2.8 1.94–4.1 19441 07 7 0.7 05809 0.58–0.9 5 33 3.3 109102 1.09–10.2 12 1.2 10015 1.00–1.5 000 0.00 22. -22 <0.00 0.01 01 2. 1.94–4. 1944 0. 0580 0.58–0. 3. 10910 1.09–10. 1. 1001 1.00–1. 0.0 -2 <0.0 1.94–4 194 058 0.58–0 1091 1.09–10 100 1.00–1 - <0. 1.94– 19 05 0.58– 109 1.09–1 1.00– <0 1.94 0.58 1.09– 1.00 1.9 0.5 1.09 1.0

Aim The study aimed to evaluate the association between oral health and academic performance and/or school absenteeism. Methods Electronic searches were performed of the PubMed, Web of Science, SCOPUS and LILACS/BVS databases. We included observational studies that evaluated the association between dental caries, tooth loss, dental pain or oral health status with school absenteeism or academic performance. The studies had to contain a representative sample of the population: schoolchildren, children or adolescents. After the removal of duplicates, the electronic searches produced 3,789 articles. Of these, 25 studies were included in the systematic review and 13 in the meta-analysis. Results Considering all the studies evaluated in the meta-analysis, seven articles satisfied 100% of the Joanna Briggs Institute Critical Appraisal checklist, and six contained between 90% and 75% positive answers. The pooled effects showed that the chances of school absenteeism were 31% higher in subjects with dental caries (OR 1.31; 95%CI 1.12-1.54). Students with fair/poor dental health had a 50% higher chance of suffering poor academic performance (OR 1.50; 95%CI 1.22-1.84) and 34% higher chance of having problems at school (OR 1.34; 95%CI 1.06-1.70). Students with a history of toothache had a 3.7 higher chance of being absent from school (OR 6.65; 95%CI 1.60-8.32) and 71% higher chance of missing class due to toothache (OR 1.71; 95%CI 1.15-2.56). Subjects with a history of toothache had a 2.5 times higher chance of suffering poor academic performance (OR 2.58; 95% CI 2.04-3.27). Conclusion Therefore, students with oral problems were more likely to take time off school and present inferior academic performance. andor PubMed Science LILACSBVS LILACS BVS databases loss population schoolchildren adolescents duplicates 3789 3 789 3,78 these 2 1 metaanalysis. metaanalysis meta analysis. analysis meta-analysis metaanalysis, analysis, 100 checklist 90 75 answers 31 OR 1.31 131 95CI 95 1.121.54. 112154 1.12 1.54 . 12 54 1.12-1.54) fairpoor fair 50 1.50 150 1.221.84 122184 1.22 1.84 22 84 1.22-1.84 34 1.34 134 1.061.70. 106170 1.06 1.70 06 70 1.06-1.70) 37 7 3. 6.65 665 6 65 1.608.32 160832 1.60 8.32 60 8 32 1.60-8.32 71 1.71 171 1.152.56. 115256 1.15 2.56 15 56 1.15-2.56) 5 2. 2.58 258 58 2.043.27. 204327 2.04 3.27 04 27 2.04-3.27) Therefore 378 78 3,7 10 9 1.3 121 1.121.54 11215 112 1.1 154 1.5 1.12-1.54 221 1.221.8 12218 122 1.2 184 1.8 1.22-1.8 061 1.061.70 10617 106 1.0 170 1.7 0 1.06-1.70 6.6 66 608 1.608.3 16083 160 1.6 832 8.3 1.60-8.3 17 152 1.152.56 11525 115 256 1.15-2.56 043 2.043.27 20432 204 2.0 327 3.2 2.04-3.27 3, 1. 1.121.5 1121 11 1.12-1.5 1.221. 1221 18 1.22-1. 1.061.7 1061 1.06-1.7 6. 1.608. 1608 16 83 8. 1.60-8. 1.152.5 1152 1.15-2.5 2.043.2 2043 20 2.04-3.2 1.121. 1.12-1. 1.221 1.22-1 1.061. 1.06-1. 1.608 1.60-8 1.152. 1.15-2. 2.043. 2.04-3. 1.121 1.12-1 1.22- 1.061 1.06-1 1.60- 1.152 1.15-2 2.043 2.04-3 1.12- 1.06- 1.15- 2.04-

ABSTRACT OBJECTIVE To describe two low-burden diet quality scores and evaluate their performance in reflecting the dietary share of the least and most processed foods defined within the Nova food system classification. METHODS This cross-sectional study included data from the NutriNet-Brasil cohort. Participants answered the Nova24hScreener, a 3-minute self-administered questionnaire measuring the consumption of a set of foods on the day before. Food items included in this tool belong to two main groups of the Nova classification: unprocessed or minimally processed whole plant foods (WPF, 33 items) and ultra-processed foods (UPF, 23 items). Two scores were obtained by summing the number of items checked: the Nova-WPF and the Nova-UPF. We compared the scores, respectively, with the dietary intake (% of total energy) of all unprocessed or minimally processed whole plant foods and all ultra-processed foods obtained from a full self-administered web-based 24-hour recall performed on the same day. RESULTS The approximate quintiles of each score had a direct and linear relationship with the corresponding % of energy intake (p-value for linear trend < 0.001). We found a substantial agreement between the intervals of each score and the corresponding % of energy intake (Nova-WPF score: Prevalence-Adjusted and Bias-Adjusted Kappa (PABAK) 0.72, 95%CI 0.64–0.81; Nova-UPF score: PABAK 0.79, 95%CI 0.69–0.88). CONCLUSIONS These two scores performed well against the dietary share of unprocessed or minimally processed whole plant foods and ultra-processed foods in Brazil and can be used to evaluate and monitor diet quality.

Objective: To assess the association between maternal fears about their infant/toddler and depression and anxiety during the COVID-19 pandemic. Methods: In 2019, all mothers who gave birth in hospitals in Rio Grande, RS, Brazil were asked to respond to a standardized questionnaire (baseline). We followed them between May-June 2020 (first follow-up point), August-December 2020 (second follow-up point), and from October 2021 to March 2022 (third follow-up point), and asked them if they were: (1) afraid that their infant/toddler would become infected with COVID or get sick (yes/no), (2) afraid that they would contaminate their own child with COVID, and/or (3) worried about the pandemic’s effects on their child’s future. At baseline and at all follow-up points, we assessed depressive symptoms using the Edinburgh Postnatal Depression Scale and anxiety symptoms using the Generalized Anxiety Disorder Scale, creating symptom trajectories using group-based trajectory modelling. We used multinomial logistic regression to calculate adjusted relative risk ratios (RRR). Results: A total of 1,296 mothers participated. Worrying about the pandemic’s effects on their child’s future and the fear of contaminating their own child with COVID-19 increased the risk of raising depressive symptoms to a clinical level (RRR = 4.97, 95%CI 2.32-10.64 and RRR = 3.87, 95%CI 1.58-9.47, respectively) and anxiety to a moderate level (RRR = 2.91, 95%CI 1.69-5.01 and RRR = 1.86, 95%CI 1.03-3.35, respectively). Conclusion: Fear for their children increased maternal depressive and anxiety symptoms during the pandemic. Objective infanttoddler infant toddler COVID19 19 COVID-1 pandemic Methods 2019 Grande RS baseline. . (baseline) MayJune May June 202 first followup follow up point, point , point) AugustDecember August December second third 1 (1 yes/no, yesno yes/no yes no (yes/no) 2 (2 andor 3 (3 pandemics s childs points groupbased group based modelling RRR. (RRR) Results 1296 296 1,29 participated 497 4 97 4.97 95CI CI 95 2.3210.64 2321064 2.32 10.64 32 10 64 2.32-10.6 387 87 3.87 1.589.47, 158947 1.58 9.47, 58 9 47 1.58-9.47 respectively 291 91 2.91 1.695.01 169501 1.69 5.01 69 5 01 1.69-5.0 186 86 1.86 1.033.35, 103335 1.03 3.35, 03 35 1.03-3.35 respectively. Conclusion COVID1 COVID- 201 (baseline 20 ( (yes/no 129 29 1,2 49 4.9 3210 2.3210.6 232106 232 2.3 1064 10.6 6 2.32-10. 38 8 3.8 589 1.589.47 15894 158 1.5 947 9.47 1.58-9.4 2.9 695 1.695.0 16950 169 1.6 501 5.0 0 1.69-5. 18 1.8 033 1.033.35 10333 103 1.0 335 3.35 1.03-3.3 12 1, 4. 321 2.3210. 23210 23 2. 106 10. 2.32-10 3. 1.589.4 1589 15 1. 94 9.4 1.58-9. 1.695. 1695 16 50 5. 1.69-5 1.033.3 1033 33 3.3 1.03-3. 2.3210 2321 2.32-1 1.589. 9. 1.58-9 1.695 1.69- 1.033. 1.03-3 2.321 2.32- 1.589 1.58- 1.033 1.03-

The study investigated the factors associated with the self-perception safety of dental students in clinical activities during the COVID-19 pandemic. This cross-sectional study was based on a semi-structured online (google forms) self-applied questionnaire, sent by e-mail to three private Dental Schools in Brazil. The variables were: 1) sociodemographic information; 2) questions about the measures adopted by dental schools before returning to clinical activities; 3) dental students’ self-perception of security; 4) the General Health Questionnaire. Data were submitted to Fisher’s exact test (p<0.05). Of the 294 eligible students, 97% were evaluated and 100% received previous specific biosafety training predominantly theoretical (72.16%) longer than one hour (51.55%). Most students (81.44%) felt secure performing clinical care during the COVID-19 pandemic. Students undergoing specific biosafety training for longer than one hour felt safer than those perfoming training for up to 1 hour (p=0.004). Students from schools where the aerosol-producing restriction was applied felt safer than those without restrictions (p=0.016). Women reported feeling less secure than men (p=0.046), and students who submitted to COVID-19 Specific Biosafety Training felt safer in clinical activities than those submitted to theoretical training only (p=0.011). Students from private universities presenting psychosomatic changes felt less secure in practicing clinical dental care activities (p=0.006). In conclusion, time-spent training in biosafety, restriction of the use of aerosol-producing procedures, and the gender of students were associated with the self-perception safety of students. Students with practical training felt safer in clinical activities for patients with COVID-19 than those who had only theoretical training.

Abstract Behavioral characteristics may also take part in the etiology of dental caries. Sedentary behavior, especially watching television, is associated with increased intake of foods high in fat or free sugar, which could influence the occurrence of dental caries. The aim of this study was to assess the mediating effect of eating pattern on the relationship between television exposure time and the presence of dental caries in children. A cross-sectional study was conducted with a representative sample of 580 parent-child dyads with children aged 7 to 8 years in 20 public schools in Pelotas, Brazil. Parents or legal guardians were interviewed and provided information on demographic/socioeconomic data, children’s daily television exposure time, and answered the Biological Rhythms Interview for Assessment in Neuropsychiatry for Kids (BRIAN-K-eating pattern domain). Caries was evaluated through clinical examination. The mediating effect of eating pattern on the relationship between television exposure and presence of dental caries was estimated using the parametric g-formula. Prevalence of dental caries was 63%, and 22% of children watched TV 4 or more hours per day. Television exposure had no direct effect on the dental caries experience [odds ratio (OR): 1.05 (95% confidence interval (95%CI): 0.92–1.19)]. Nevertheless, difficulty maintaining regular eating pattern mediated the natural indirect effect of television exposure time (≥ 4 hours/day) on dental caries experience [OR: 1.07 (95%CI): 1.01–1.14)]. The results of this study confirm the indirect pathway between television viewing and dental caries and the role of disordered eating patterns in this association.

Resumo O objetivo deste estudo é descrever o perfil de utilização dos serviços de atenção primária à saúde, estimado pela Pesquisa Nacional de Saúde (PNS), da população residente em domicílios cadastrados e não cadastrados na Estratégia de Saúde da Família (ESF), nos anos de 2013 e 2019. Estudo transversal realizado com microdados dos inquéritos nacionais de saúde entre 2013 e 2019. A amostra originou-se de uma amostra mestra, composta por um conjunto de unidades de áreas selecionadas em um cadastro. Variáveis sexo, idade, cor da pele, renda, escolaridade, autopercepção de saúde, domicílio cadastrado na ESF, atendimento médico no último ano, tipo de serviço que você procura quando está doente foram selecionados. As variáveis dependentes foram uso de serviços de saúde e uso de serviços públicos de saúde. As variáveis dependentes e independentes foram descritas com os respectivos intervalos de confiança e foi realizada regressão logística ajustada para cada desfecho analisado. Nos serviços públicos de saúde, menor renda, ter doenças crônicas (hipertensão arterial ou colesterol alto), estar grávida e ter uma autopercepção de saúde ruim estiveram associados à maior utilização de serviços de saúde nos dois períodos. Morar em domicílios cadastrados na ESF foi associado aos serviços de saúde mais utilizados (públicos ou privados). A estratégia de saúde da família é uma estratégia importante para expandir o acesso de forma igualitária.

Abstract The objective of this study is to describe the profile of use of primary health care services, estimated by the PNS, of the population living in households registered and not registered with the Famly Health Strategy - FHS, in the years 2013 and 2019. Cross-sectional study carried out using microdata from national health surveys 2013 and 2019. The sample originated from a master sample, consisting of a set of units from selected areas in a register..The variables sex, age, skin color, income, education, self-perceived health, home registered with the FHS, medical care in the last year, type of service you seek when you are ill were selected. The dependent variables were use of health services and use of public health services. The dependent and independent variables were described with the respective confidence interval and adjusted logistic regression was performed for each outcome analyzed. In public health services, lower income, have chronic diseases (arterial hypertension or high cholesterol), be pregnant, and having a bad self-perception of health were associated with used more health services in both periods. Living in registered households was associated with more used health services (public or private). The family health strategy is an important strategy for expanding access equally.

RESUMO: Objetivos: O objetivo do presente estudo foi descrever o impacto da pandemia de covid-19 na Atenção Primária à Saúde (APS) Brasileira. Métodos: Estudo ecológico retrospectivo realizado com dados de municípios brasileiros, obtidos nos sistemas de informação do Sistema Único de Saúde (SUS). Os desfechos do estudo foram as consultas médicas, procedimentos de pré-natal e tratamento de diabetes. A exposição foi a ocorrência da pandemia de covid-19, a partir do primeiro caso notificado no Brasil. Regressões binomiais negativas de efeitos mistos multinível foram utilizadas para analisar a associação entre o número de procedimentos por 10.000 habitantes e a pandemia de covid-19. Resultados: Dados de 5.564 municípios brasileiros foram incluídos no presente estudo. Em relação à consulta médica, a maior redução devido à pandemia em curso ocorreu em maio (IRR = 0,27, IC95% 0,24 - 0,30). Para os procedimentos de pré-natal, a redução foi de 65% (IRR = 0,35, IC95% 0.32 - 0.38), também em maio. Ainda assim, os procedimentos de tratamento do diabetes tiveram maiores reduções em abril (IRR = 0,24, IC95% 0,11 - 0,53) e maio (IRR = 0,19, IC95% 0,09 - 0,43) de 2020. De fevereiro a dezembro de 2020, a pandemia de covid-19 impactou significantemente o total de procedimentos avaliados. Conclusão: Os achados mostraram uma redução de procedimentos de pré-natal, diabetes e consultas médicas realizadas na Atenção Primária à Saúde (APS) do Brasil, após o início da pandemia de covid-19.

ABSTRACT: Objectives: The purpose of this study was to describe the impact of the COVID-19 pandemic on Primary Health Care in Brazil. Methodology: This retrospective ecological study was carried out using Brazilian municipality data obtained from the information systems of the National Public Health System. The outcomes were medical appointments, prenatal procedures and diabetes care. The exposure variable was the occurrence of the COVID-19 pandemic, based on the first case reported in Brazil. Multilevel mixed-effects negative binomial regression was used to analyze the association between the number of procedures per 10,000 inhabitants and COVID-19. Results: Data from 5,564 Brazilian municipalities were included in the present study. Regarding medical appointments, the largest reduction occasioned by the pandemic occurred in May (IRR = 0.27, 95%CI 0.24 – 0.30). Prenatal procedures were reduced by 65% (IRR = 0.35, 95%CI 0.32 – 0.38), also in May. In addition, diabetes care saw the biggest reductions in April 2020 (IRR = 0.24, 95%CI 0.11 – 0.53) and May 2020 (IRR = 0.19, 95%CI 0.09 – 0.43). From February to December 2020, the pandemic had a significant effect on the total number of procedures evaluated. Conclusion: The findings showed a reduction in prenatal procedures, diabetes and medical consultations performed in Brazil's Primary Health Care, following the onset of the COVID-19 pandemic.

Resumo Objetivo Analisar a associação entre dor dentária, uso de serviços odontológicos e absenteísmo escolar em adolescentes brasileiros. Métodos Estudo transversal, sobre dados da Pesquisa Nacional de Saúde do Escolar (PeNSE 2015). A variável dependente do estudo foi o absenteísmo escolar por motivo de saúde nos últimos 12 meses. Características socioeconômicas, dor dentária e utilização de serviços odontológicos foram as variáveis independentes avaliadas. Empregou-se regressão logística, para estimar odds ratio (OR) e respectivos intervalos de confiança de 95% (IC95%). Resultados Foram incluídos 102.072 escolares. A prevalência de absenteísmo por motivo de saúde foi de 53,7% (IC95% 53,2;54,3). Pela análise ajustada, houve associação entre dor dentária e absenteísmo (OR=1,35 - IC95% 1,26;1,45), e aumento na ocorrência de absenteísmo conforme o maior número de consultas odontológicas. Conclusão Os resultados sugerem que a dor dentária e a frequência de consultas odontológicas podem estar relacionadas ao absenteísmo escolar.

Resumen Objetivo Analizar la asociación entre dolor dental, el uso de servicios dentales y el absentismo escolar en adolescentes brasileños. Métodos Estudio transversal con datos de la Encuesta Nacional de Salud Escolar (PeNSE 2015). La variable dependiente del estudio fue el absentismo escolar por razones de salud en los últimos 12 meses. Características socioeconómicas, dolor dental y frecuencia del uso de los servicios dentales fueron las variables independientes evaluadas. La regresión logística se usó para estimar los odds ratio (OR) e intervalos de confianza del 95% (IC95%). Resultados Se incluyeron datos de 102.072 estudiantes. La prevalencia de absentismo por razones de salud fue del 53,7% (IC95% 53,2; 54,3). En el análisis ajustado, hubo una asociación entre el dolor dental y el absentismo escolar (OR=1,35; - IC95% 1,26; 1,45), y un aumento del absentismo según el mayor número de consultas dentales. Conclusión Los resultados sugieren que el dolor dental y la frecuencia de las visitas al dentista pueden estar relacionados con el absentismo escolar.

Abstract Objective To analyze association between dental pain, use of dental services and school absenteeism in Brazilian adolescents. Methods This was a cross-sectional study with data from the National School Health Survey (PeNSE 2015). The study’s dependent variable was school absenteeism due to health reasons in the last 12 months. Socioeconomic characteristics, dental pain and use of dental services were the independent variables evaluated. Logistic regression was used to estimate odds ratios (OR) and respective 95% confidence intervals (95%CI). Results Data on 102,072 schoolchildren were included. Absenteeism prevalence due to health reasons was 53.7% (95%CI 53.2;54.3). In the adjusted analysis, there was association between dental pain and school absenteeism (OR=1.35 - 95%CI 1.26;1.45), and an increase in absenteeism occurrence the greater the number of dental visits. Conclusion The results suggest that dental pain and frequency of dental visits may be related to school absenteeism.