Resumen En este trabajo, se hace una reflexión en torno a una filosofía de la educación centrada en la percepción de ritmos acordes con formas de relación con el ambiente, basadas en el cuidado hacia la vida. En esta dirección, se realiza un análisis ecocrítico de la obra Terrenal. Pequeño misterio ácrata (2014) de Mauricio Kartun, la cual permite teorizar sobre la relevancia de la atención a los ritmos, los pulsos y las armonías de textos literarios (y otros formatos artísticos) en la construcción de propuestas educativas que aspiren a dislocar la lógica expansiva propia de las actuales sociedades del capitalismo globalizado. El análisis crítico de esta cuestión es de especial relevancia a la hora de vislumbrar modos de vida alternativos que puedan relacionarse, de manera más armónica, con las escalas y las proporciones emergentes de la interacción entre la multiplicidad de existencias que conforman un territorio de vida.

Abstract This paper reflects on a philosophy of education centered on the perception of rhythms in accordance with forms of relationship with the environment, based on care for life. In this direction, we will carry out an ecocritical analysis of the play Terrenal. Pequeño misterio ácrata (2014) by Mauricio Kartun, which allows theorizing about the relevance of paying attention to the rhythms, pulses, and harmonies of literary texts (and other artistic formats) in the construction of educational proposals that aspire to dislocate the expansive logic of the current societies of globalized capitalism. The critical analysis of this issue is of particular relevance when it comes to envisioning alternative ways of life that can be related, in a more harmonious way, to the scales and proportions emerging from the interaction between the multiplicity of beings that make up a territory of life.

Resumo Neste trabalho, é feita uma reflexão em torno de uma filosofia de educação centrada na percepção dos ritmos de acordo com as formas de relação com o meio ambiente, fundamentadas no cuidado da vida. Nessa direção, realiza-se uma análise ecocrítica da obra Terrenal. Pequeño misterio ácrata (2014), de Mauricio Kartun, que permite teorizar sobre a relevância da atenção aos ritmos, as pulsações e as harmonias dos textos literários (e de outros formatos artísticos) na construção de propostas educativas que aspirem a deslocar a lógica expansiva característica das sociedades atuais do capitalismo globalizado. A análise crítica desta questão é de particular relevância quando se trata de vislumbrar formas alternativas de vida que possam relacionar-se, de maneira mais harmoniosa, com as escalas e proporções que emergem da interação entre a multiplicidade de existências que compõem um território de vida.

Resumen Introducción: el lupus eritematoso sistémico (LES) es una enfermedad sistémica que se ha asociado a mayor severidad con la infección por SARS-CoV-2. Particularmente la alta actividad de la enfermedad y algunos inmunosupresores se han vinculado a peores desenlaces. Objetivos: describir las características por SARS-CoV-2 en pacientes con LES en Argentina del registro SAR-COVID y establecer los factores asociados a peor desenlace de la misma. Materiales y métodos: estudio observacional. Se incluyeron pacientes con diagnóstico de LES con infección confirmada por SARS-CoV-2 (RT-PCR y/o serología positiva) del registro SAR-COVID. Los datos se recolectaron desde agosto de 2020 hasta marzo de 2022. El desenlace de la infección se midió mediante la escala ordinal de la Organización Mundial de la Salud (EO-OMS). Se definió COVID-19 severo con un valor EO-OMS ≥5. Análisis descriptivo, test T de Student, test de Mann Whitney U, ANOVA, chi2 y Fisher. Regresión logística múltiple. Resultados: se incluyeron 399 pacientes, el 93% de sexo femenino, con una edad media de 40,9 años (DE 12,2). El 39,6% tenía al menos una comorbilidad. Al momento de la infección, el 54,9% recibía glucocorticoides, el 30,8% inmunosupresores y el 3,3% agentes biológicos. La infección por SARS-CoV-2 fue leve en la mayoría de los casos, mientras que un 4,6% tuvo curso severo y/o falleció. Estos últimos presentaban comorbilidades, usaban glucocorticoides y tenían síndrome antifosfolipídico (SAF) con mayor frecuencia y mayor actividad de la enfermedad al momento de la infección. En el análisis multivariado, la hipertensión arterial, el diagnóstico de SAF y el uso de glucocorticoides se asociaron a hospitalización severa y/o muerte por COVID-19 (EO-OMS ≥5). Conclusiones: en esta cohorte de pacientes con LES con infección por SARS-CoV-2 confirmada, la mayoría cursó de manera sintomática, un 22,1% fue hospitalizado y un 5% requirió ventilación mecánica. La mortalidad fue cercana al 3%. El diagnóstico de SAF, tener hipertensión arterial y el uso de glucocorticoides se asociaron significativamente con COVID-19 severo.

Abstract Introduction: systemic lupus erythematosus (SLE) is a systemic disease that has been associated with greater severity with SARS-CoV-2 infection. Particularly high disease activity and some immunosuppressants have been linked to worse outcomes. Objectives: to describe the characteristics due to SARS-CoV-2 in patients with SLE in Argentina from the SAR-COVID registry and to establish the factors associated with a worse outcome of the same. Materials and methods: observational study. Patients diagnosed with SLE with confirmed SARS-CoV-2 infection (RT-PCR and/or positive serology) from the SAR-COVID registry were included. Data was collected from August 2020 to March 2022. The outcome of the infection was measured using the World Health Organization - ordinal scale (WHO-OS). Severe COVID-19 was defined as an WHO-OS value ≥5. Descriptive analysis, Student's T test, Mann Whitney U, ANOVA, chi2 and Fisher. Multiple logistic regression. Results: a total of 399 patients were included, 93% female, with a mean age of 40.9 years (SD 12.2), 39.6% had at least one comorbidity. At the time of infection, 54.9% were receiving glucocorticoids, 30.8% immunosuppressants, and 3.3% biological agents. SARS-CoV-2 infection was mild in most cases, while 4.6% had a severe course and/or died. The latter had comorbidities, used glucocorticoids and had antiphospholipid syndrome (APS) more frequently and higher disease activity at the time of infection. In the multivariate analysis, high blood pressure, the diagnosis of APS, and the use of glucocorticoids were associated with severe hospitalization and/or death from COVID-19 (WHO-EO ≥5). Conclusions: in this cohort of SLE patients with confirmed SARS-CoV-2 infection, most had a symptomatic course, 22.1% were hospitalized, and 5% required mechanical ventilation. Mortality was close to 3%. The diagnosis of APS, having high blood pressure, and the use of glucocorticoids were significantly associated with severe COVID-19.

Resumen En un juego de aproximaciones y evocaciones, Noé Jitrik nos invita en estas páginas a explorar la mutua imbricación de lo político, lo literario y lo psicoanalítico como dimensiones que impregnan su filosofía de la escritura. Esta última, cuya forma manifiesta se transfigura en su insinuación, aloja la afluencia de fuerzas en la lectura y desde ella trama sus modos y gestualidades. Así se manifiestan los sedimentos y restos constitutivos de un pensamiento que desplaza la idea mecánica de mera aplicación de los discursos. A su vez, lo poético entreteje lo palpitante del lenguaje que anuda aspectos de lucha y alteridad en el acto de escribir. En consonancia, se avista un combate contra el silencio como espacio en blanco y contra el silenciamiento generado por lógicas epistémicas hegemónicas. Frente a este panorama, la escritura se trenza de modo que afloran otras dimensiones del fracaso en relación con el intento de capturar el sentido, colmar el silencio o eliminar el olvido. Estas contracaras del acto escritural terminan por delinear un juego entre memoria y olvido, entre presencia y ausencia, entre imposibilidad y negatividad que remite al modo en que silbidos del silencio acechan mientras el trazo florece en su picardía filosófica.

Resumo Num jogo de aproximações e evocações, Noé Jitrik nos convida, nestas páginas, a explorar o entrelaçamento mútuo do político, do literário e do psicanalítico como dimensões que permeiam a sua filosofia da escrita. Este último, cuja forma manifesta se transfigura em sua insinuação, abriga o influxo de forças na leitura e a partir daí traça seus modos e gestos. É assim que se manifestam os sedimentos e os restos constituintes de um pensamento que deslocam a ideia mecânica de mera aplicação dos discursos. Ao mesmo tempo, o poético entrelaça o latejar da linguagem que une aspectos de luta e alteridade no ato de escrever. Em consonância com o que este ato implica, avista-se um combate ao silêncio como espaço em branco e ao silenciamento gerado pelas lógicas epistêmicas hegemônicas. Neste contexto, a escrita é torcida de tal forma que outras dimensões do fracasso emergem em relação à tentativa de captar significados, preencher o silêncio ou eliminar o esquecimento. Essas faces contrárias do ato escritural acabam delineando um jogo entre memória e esquecimento, entre presença e ausência, entre impossibilidade e negatividade, que remete ao modo como espreitam os assobios do silêncio enquanto a linha floresce em sua travessura filosófica.

Abstract In a game of approximations and evocations, Noé Jitrik invites us to explore the mutual interweaving of the political, the literary, and the psychoanalytic as dimensions that permeate his philosophy of writing. The latter, whose manifestation is transformed in its insinuation, houses the multiple forces of the act of reading, and then plots its forms and gestures. In doing so, we observe the sediments and possibilities for a way of thinking that rejects the mere mechanical application of discourses. At the same time, it gives rise to a language that ties together struggle and otherness in the act of writing. Therefore, it presents a form of resistance against silence as a blank space, and against the act of silencing produced by hegemonic epistemologies. In this context, there emerge in the act of writing other dimensions of failure in relation to the attempt to capture meaning, fill gaps or eliminate forgetfulness. These other sides of writing outline a game between memory and forgetting, between presence and absence, and between impossibility and negativity, which point to how the whistles of silence prowl while writing flourishes in its philosophical mischief.

ABSTRACT INTRODUCTION: Congenital heart diseases (CHD) are structural anomalies of the heart and great vessels present at birth. CHD encompass a broad spectrum of anomalies affecting around 0.6%-0.9% of all live births worldwide. In Argentina, CHD account for one-third of all birth defects. Their etiology is heterogeneous; however, family recurrence has been observed in accordance with the influence of genetic factors. The objective of the study was to analyze the presence of chromosomal abnormalities, genomic imbalances and/or sequence variants in a sample of children with CHD in Argentina. METHODS: A total of 289 patients with CHD up to 16 years old were included. Karyotyping was performed for patients with other birth defects, and genomic regions associated with CHD were studied by multiplex ligation-dependent probe amplification (MLPA) in patients with conotruncal CHD. In selected samples, genomic imbalances and/or sequence variants were analyzed by array comparative genomic hybridization (a-CGH) or by direct sequencing of the NKX2-5 gene, respectively. RESULTS: There were 9 patients with chromosomal abnormalities, 21 had genomic imbalances detected by MLPA and 8 by array- CGH. No pathogenic variants were found in NKX2-5. DISCUSSION: The genetic cause was found in 13% of the analyzed cases. This work represents the first study in patients with CHD either isolated or associated with other birth defects in Argentina.

RESUMEN INTRODUCCIÓN: Las cardiopatías congénitas (CC) son causadas por el desarrollo anómalo del corazón durante el período embriofetal. Abarcan un amplio espectro de anomalías estructurales de las cavidades cardíacas o de los grandes vasos, con una prevalencia mundial de 6 a 9 por 1000 nacimientos. En Argentina constituyen un tercio de las anomalías congénitas (AC) al nacimiento. Si bien su etiología es heterogénea, se ha observado recurrencia familiar acorde con la influencia de factores genéticos. El objetivo del estudio fue evaluar la presencia de anomalías cromosómicas, desbalances genómicos o variantes de secuencias en una muestra de niños afectados con CC en Argentina. MÉTODOS: Se incluyó a 289 pacientes con CC de hasta 16 años. Se realizó un cariotipo para pacientes con otras AC y análisis por amplificación múltiple de sondas dependiente de ligación (MLPA) de regiones genómicas asociadas a CC para aquellos con CC conotroncales. En muestras seleccionadas, se analizaron desbalances genómicos por microarreglos de ADN (array-CGH) o variantes de secuencia en el gen NKX2-5. RESULTADOS: Hubo 9 pacientes que presentaron anomalías cromosómicas, 21 desbalances por MLPA y 8 por array-CGH. No se hallaron variantes patogénicas en NKX2-5 en los casos estudiados. DISCUSIÓN: Se halló la causa de la afección en el 13% de los casos analizados. El estudio de pacientes con CC aisladas o asociadas a otras AC no había sido abordado previamente en Argentina mediante este algoritmo.

No âmbito de teorias duales, a tomada de decisões baseia-se em dois tipos de processamento de informações: intuitivo e racional. Inspirados por este marco conceitual, nossos objetivos foram desenvolver um breve instrumento de medição de autoavaliação para avaliar as bases afetivas e racionais para a tomada de decisões urgentes em circunstâncias extremas e estudar suas propriedades psicométricas. As amostras incluíram cadetes de uma academia militar e participantes da população em geral. Os resultados mostraram evidências de confiabilidade aceitável, bem como validade estrutural, convergente e discriminante para as inventário Bases for Urgent Decisions under Extreme Circumstances inventory (BUDECI; Bases para Decisões Urgentes em Circunstâncias Extremas, português), o novo inventário de 8 itens.

In the framework of dual-type theories, decision making is based on two types of information processing: intuitive and rational. Inspired by this framework, our aims were to develop a brief self-rating measurement instrument to assess the affective and rational bases for urgent decision-making under extreme circumstances, and to study its psychometric properties. The samples comprised cadets from a military academy and participants from the general population. The results showed evidence of acceptable reliability as well as structural, convergent, and discriminant validity for the Bases for Urgent Decisions under Extreme Circumstances Inventory (BUDECI), the new 8-item inventory.

The so called dual models that emerged in the70s suggest that there are two types of information processing with opposite characteristics to one another and are related to ways of making emotional and rational decisions. This research focused on the study of emotional and rational peace keepers' decision making. Peace keepers are military personnel that participate in United Nations Organization (UN) international forces in order to be deployed in conflict zones around the world to maintain peace and to provide humanitarian aid. In these missions, peacekeepers' behavior is ruled by codes which are committed to ensuring the highest standards of conduct in UN military operations. According to these UN rules, servicemen should not intervene in situations of not obvious risk or no imminent physical harm to civilians of the local population. It is worth noting that inappropriate peacekeepers ´interventions can have serious negative consequences in the mission. Consequently, in the predeployment stage peacekeepers are trained by qualified military personnel with core operational and cultural information related the country where they are going to be deployed to have an effective performance during their duty. At the moment of our research, Argentinian peacekeepers were deployed in Haiti. The objective of this study was to study the effects of the emotional / rational decision-making mode, the Argentine's soldiers training as peacekeeper, and the level of cultural saturation in the observed situations; over the decision to intervene in multicultural situations. For this study, a piece of software called SITDE with a series of audible videos that reflect different situations related to the UN peacekeeper mission was used. There were two SITDE versions that differed from each other due to the level of cultural representation. One version contains a set of videos with high typical Haitian´s cultural saturation. The other version, a set of homologous videos related to the other series, includes scenes with fewer aspects of Haitian´s elements. After watching each video participants had to decide whether to intervene or not to intervene in the observed scenes. They should report its decision by clicking on a screen displaying two buttons with the corresponding decision. The software recorded the participant's response and the response time of each scene. This study sought to corroborate three hypotheses about peacekeepers' decision making on culturally diverse scenes in which they had no danger of imminent attack: (a) decision making based on rational information processing compared to decision making based on affective / emotional processing leads to not intervene; (b) military experts in international peace missions (i.e., military with UN training) compared to the inexperienced (military with no UN training) make fewer interventions and (c) the high saturation of cultural elements of the scenes compared to scenes of low saturation of cultural elements leads to make fewer interventions. The hypotheses were verified through a 2 x 2 x 2 factorial design. The 2 x 2 x 2 factorial design included the independent variables decision making modality, training as peace -keepers, and cultural saturation of the observed situation; and the dependent variable intervention in the observed situation. The military personnel´s decision-making was manipulated by differentiated instruction, and the cultural saturation of scenes was manipulated by the use of the two SITDE versions. Additionally, it has been analyzed the relationship between the individual trend to the emotional / rational decision-making and relevant variables. It was found that the individual trend to the rational decision making in urgent situations is negatively associated to the reaction time. The results are discussed related to the frame of the dual theories.

Los llamados modelos duales proponen dos tipos de procesamiento de la información, relacionados con los modos de tomar decisiones emocionales y racionales. La investigación realizada se focalizó en el estudio de la toma de decisión en soldados para el mantenimiento de la paz (i.e., Cascos Azules). Ellos integran el personal militar que envía la Organización Naciones Unidas (ONU) para mantener la paz y brindar ayuda humanitaria en zonas de conflicto. Se empleó un diseño factorial 2x2x2, con las variables independientes: modalidad decisoria, entrenamiento como soldado para la paz y saturación cultural de la situación observada, y con la variable dependiente respuesta de intervención en la situación observada. Según las reglas de la ONU, no se debería intervenir en las situaciones multiculturales presentadas en este estudio. Se corroboraron tres hipótesis: (a) la toma de decisión basada en el procesamiento racional de la información en comparación con la toma de decisión basada en el procesamiento afectivo / emocional, lleva a no intervenir, (b) los expertos en misiones militares de paz internacionales (i.e., militares con entrenamiento de casco azul) en comparación con los inexpertos (i.e., militares sin dicho entrenamiento) realizan menos intervenciones y (c) la alta saturación de elementos culturales de las escenas en comparación a las escenas de baja saturación de elementos culturales lleva a realizar menor cantidad de intervenciones. Adicionalmente, se halló que la tendencia individual a tomar decisiones racionales urgentes está asociada negativamente con el tiempo de reacción. Se discuten los resultados en relación al marco de las teorías duales.

It is known that to achieve effective action in contexts characterized by cultural diversity and uncertainty, decision-making strategies are needed that involve processing or analytical intuitive mode, depending on circumstances (Azzollini, Torres, Depaula, Clotet & Nistal, 2010). The objective of this study was to determine experimentally whether there are differences in the ways of processing information and efficiency in decision making, depending on the age of the subjects. It's been evaluated the mode of processing and determining the effectiveness of decisions made by 116 volunteer soldiers of different ages, in different situations in which they experimentally manipulated the level of cultural uncertainty. The results indicate that older subjects show a clear trend towards the use of predominantly intuitive processes in decision-making (F=3,473, p=0.034), with a marginally significant loss of eficacy (F=3,045, p=0.052)

Es sabido que para el logro de acciones eficaces, en contextos caracterizados por la diversidad cultural y la incertidumbre, se requieren estrategias decisorias que impliquen procesamiento de modalidad intuitiva o analítica, según las circunstancias (Azzollini, Torres, Depaula, Clotet & Nistal, 2010). El objetivo de este trabajo es determinar experimentalmente si existen diferencias en los modos de procesamiento de la información y la eficacia a la hora de tomar decisiones, en función de la edad de los sujetos. Se evaluó la modalidad de procesamiento decisoria y la efectividad de las decisiones tomadas por 116 soldados voluntarios de distintas edades, en diferentes situaciones en las que se manipuló experimentalmente el grado de incertidumbre cultural. Los resultados indican que los sujetos con mayor edad presentan una clara tendencia hacia el uso de procesos predominantemente intuitivos en la toma de decisiones (F=3.473, p=0.034), con una pérdida marginalmente significativa de la eficacia (F=3.045, p=0.052)