Abstract Introduction Returning to work is an important cancer recovery milestone. Permanent colostomy can be required for rectal cancer treatment and can significantly impact well-being. We aimed to evaluate the impact of permanent colostomy on health-related quality of life and return to work in patients with rectal cancer. Methods This was a retrospective cohort study on 23 employed patients receiving curative surgery for rectal cancer requiring permanent colostomy. Demographic and health-related quality-of-life questionnaires (the Colostomy Impact Score (CIS), the EORTC Quality of Life Questionnaire (QLQ)-C30, and the EORTC QLQ-CR29) were posted to eligible patients. Results On average, patients (10 female, 13 male, mean age 61.8 years) were 5.0 ± 3.5 years post-surgery. At the time of questioning, 73.9% had returned to work (21.7% changed their type of work), while 17.4% never returned to work. Of those that returned to work, 11.8% returned within 1 month of surgery, while 23.5% had not returned after 12 months. Comparison of CIS between patients that returned to the same work (14.6 ± 0.93), changed their work (13.0 ± 0.74), and did not return to work (14.3 ± 2.3) revealed no significant differences (p = 0.36). CIS did not correlate with days worked on return, or time to return to work (p > 0.05). Conclusion Returning to work following rectal cancer treatment with permanent colostomy is challenging, with 17.4% never returning to work. Of those who returned to work, 23.5% required more than 12 months. This was not associated with CIS in our study. milestone wellbeing. wellbeing well being. being well-being healthrelated health related 2 qualityoflife CIS, , (CIS) QLQC30, QLQC30 QLQC QLQ C30, C30 C (QLQ)-C30 QLQCR29 QLQCR CR29 CR QLQ-CR29 average 10 (1 female male 618 61 8 61. 50 5 0 5. 35 3 3. postsurgery. postsurgery post surgery. post-surgery questioning 739 73 9 73.9 21.7% 217 21 7 (21.7 work) 174 17 4 17.4 118 11 11.8 235 23.5 months 14.6 146 14 6 (14. 0.93, 093 0.93 93 0.93) 13.0 130 (13. 0.74, 074 0.74 74 0.74) 14.3 143 2.3 p 0.36. 036 0.36 . 36 0.36) 0.05. 005 0.05 05 0.05) challenging (CIS QLQC3 C3 (QLQ)-C3 QLQCR2 CR2 QLQ-CR2 ( 73. 21.7 (21. 17. 11. 23. 14. (14 09 0.9 13. (13 07 0.7 2. 03 0.3 00 0.0 (QLQ)-C QLQ-CR 21. (21 0. (2

For the first time in Argentine bibliography a chondroma of the vertebra with extradural dorsal medular compression, is described. The clinical characteristics of the onset by intermitent medular claudication of Dejerine and the painless evolution until surgical intervention, are stressed. The bibliography is put up to date and the radiographics signs and the pathologic anatomy of the chondromas, are studied.