Abstract Objective: To evaluate the effectiveness of Antimicrobial Photodynamic Therapy (aPDT), associated with scaling and root planing in the non-surgical periodontal treatment of individuals with Down Syndrome. Material and Methods: A controlled, randomized, split-mouth study was conducted. A total of 8 participants diagnosed with Down Syndrome aged 17-38 years of both sexes with clinical periodontitis were included in the study. Participants were treated at least three times: at the baseline, Plaque Index (PI), Bleeding on Probing (BOP), and Probing Pocket Depth (PPD) were obtained. After one week, conventional scaling and root planing were performed, and two quadrants were randomly selected for aPDT application. The reassessment was obtained one month after the aPDT application. The significance level was set at 5%. Analyses were performed considering a 95% confidence interval. Results: In the intergroup evaluation, no statistically significant differences were observed (p>0.05). In the intragroup evaluation, no statistically significant variations were observed in relation to the PI (p>0.05) and PPD (p>0.05); however, a statistically significant reduction in the BOP was observed between the test group (p=0.013) and control group (p=0.015). Conclusion: The use of aPDT as adjuvant therapy did not promote additional benefits in decreasing PI and PPD after 1 month of treatment. However, a significant reduction in the BOP was observed in the intragroup evaluation.

Abstract Objective: To evaluate, in vitro, the effect of photodynamic therapy (PDT) compared to laser therapy and the use of a photosensitizer alone. Material and Methods: The following therapies were used: PDT, laser therapy and photosensitizer alone. For PDT, methylene blue (MB) at different concentrations and red laser InGaAlP 660nm were used. For the use of low-power laser (LPL) alone, red laser InGaAlP 660 nm and infrared laser AsGaAl, 830 nm, both in continuous emission were used. Standard ATCC strains of Staphylococcus aureus (S. aureus), Escherichia coli (E. coli) and Pseudomonas aeruginosa (P. aeruginosa) species were used. The antibacterial effect of PDT was quantified by the diameter of the inhibition halos. Results: PDT (LPL 660 nm, 320 J/cm2) with MB at concentration of 50 µg/mL showed antibacterial efficacy only when tested against S. aureus and E. coli strains, as well as with the isolated use of MB at the same concentration. Using LPL alone, whether red or infrared, with different dosimetry, no antibacterial effect was observed. In none of the therapeutic modalities used, P. aeruginosa inactivation was observed. Conclusion: Antibacterial effects of PDT (LPL 660 nm + MB 50 µg/mL) were observed for S. aureus and E. coli, as well as with the isolated use of MB (50 µg/mL). For P. aeruginosa, no antibacterial effect with any of the protocols recommended in the study was observed.

Síndrome da Apneia/Hipopneia Obstrutiva do sono (SAHOS) é uma doença crônica, evolutiva que pode ocasionar graves repercussões comportamentais, cardiovasculares e neurológicos ao paciente.O objetivo deste estudo é realizar uma revisão sistematizada sobre a importância da abordagem multidisciplinar no diagnóstico e tratamento da Síndrome da Apneia e Hipopnéia Obstrutiva do sono. Vários profissionais da área de saúde podem atuar no diagnóstico e tratamento desta síndrome, destacando-se atuação dos médicos, dentistas, fisioterapeutas e fonoaudiólogos.

Obstructive Sleep Apnea/Hypopnea Syndrome (OSAHS) is a chronic and progressive disease, which can cause serious behavioral, cardiovascular and neurological repercussions to the patient. This study is aimed to conduct a systematic review about the importance of the multidisciplinary approach to diagnosis and treatment of Obstructive Sleep Apnea/Hypopnea Syndrome. Several healthcare professionals can work in the diagnosis and treatment of this syndrome, but the emphasis is given to doctors, dentists, physiotherapists and speech therapists actions.

Objetivo: avaliar parâmetros polissonográficos de pacientes com indicação para uso de AOPMs.Métodos: estudaram-se, retrospectivamente, os dados de prontuários com base em itens que compunham a polissonografia de 124 pacientes com idade entre 25 e 77 anos, que não estavam fazendo nenhum tratamento para distúrbios do sono. O estudo foi aprovado pelo Comitê de Ética em Pesquisa da instituição de origem (CAE n o 0378.0.133.000-10).Resultados: 46,8% dos pesquisados tinham diagnóstico de apnéia leve, 91,8% roncavam e tinha uma eficiência do sono insatisfatória. Dos pacientes que roncavam, a quase totalidade apresentava SAHOS. A menor saturação de oxigênio durante o exame variou entre 60% e 97%, com mais de quatro quintos da amostra com índices abaixo de 90%.Conclusão: não houve relação significante entre os índices de apnéia e os níveis de saturação de oxi-hemoglobina. A eficiência do sono esteve diretamente relacionada à severidade da SAHOS, com evidências estatísticas; a oximetria pode ser um valioso instrumento para o diagnóstico da SAHOS, mas não pode ser única fonte para referenciar a gravidade da síndrome; o sono REM foi insatisfatório na maioria dos pesquisados, e este esteve significantemente relacionado à eficiência do sono.

Purpose: to evaluate some polysomnographic parameters of patients that were referred to use mandibular protusion device (MPD).Methods: we studied, retrospectively, data from medical records with items that made up polysomnography of 124 patients aged between 25-77 years, that were not having any treatment for OSAHS. The study was approved by the Ethics Committee of origin institution (CAE number 0378.0.133.000-10).Results: 46.8% of respondents had mild apnea, snoring and most had poor sleep efficiency. Almost all of these patients had OSAHS. The lower oxygen saturation during the test ranged from 60% to 97%, with more than four fifths of the sample rates below 90%.Conclusion: there was no significant relationship between rates of apnea and the levels of oxyhemoglobin saturation. Sleep efficiency was directly related to the severity of OSA, with statistical evidence; oximetry can be a valuable tool for the diagnosis of OSA, but cannot be sole source to refer to the severity of the syndrome, REM sleep was poor in most investigated, and this was significantly related to sleep efficiency.

OBEJTIVO: avaliar a eficácia do laser de baixa intensidade no tratamento da dor em pacientes com desordens temporomandibulares. MÉTODO:consistiu de um ensaio clínico randomizado divididos em dois grupos: Grupo 1: laser AsGaAl, Grupo 2: laser InGaAlP, do qual participaram 20 pacientes entre 19 e 35 anos de idade, com diagnóstico de sinais e sintomas de DTM. Os pacientes tinham a amplitude de movimento para abertura máxima da boca e lateralidade registados no início e no final do tratamento a laser. O Laser foi aplicado em quatro pontos pré-auriculares, totalizando 12 sessões três vezes por semana, durante um mês. Dor dos pacientes foi registrado com base na utilização da escala analógica visual (EAV) e também por exame físico dos pontos álgicos. RESULTADOS: observou-se redução significante (p<0,028) do nível de dor em ambos os grupos, porém no G1 a significância foi maior. A evolução do limiar de sensibilidade muscular evidenciou diferença estatisticamente significante (p<0,05) para G1 e G2. A laserterapia no Grupo 1 melhorou a abertura bucal em média de 4,643 mm, enquanto no Grupo 2, a média foi de 3,71 mm por paciente. CONCLUSÃO: houve eficácia em ambos os lasers no controle da dor e abertura bucal dos pacientes.

PURPOSE: the effectiveness of lasertherapy in the treatment o temporomandibular of pain with temporomandibular disorders. METHOD: it consisted of a randomized clinical trial divided into two groups: Group 1: AsGaAl laser; Group 2: InGaAIP laser, 20 patients between 19 and 35 years old, diagnosed with signs and symptoms of TMD. Patients had the range of motion for maximum mouth opening and laterality registered at the beginning and at the end of the laser treatment. Laser was applied in four pre-auricular points three times a week during a month, in a total of 12 sessions to each patient. The patients' pain was noted based on the use of visual analogue scale (VAS) and also by physical examination of the pain points. RESULTS: there was a significant reduction (p<0.028) of the level of pain in both treatment groups, but the G1 had higher significance. The evolution of the threshold of muscle sensivity showed a statistically significant difference for G1 and G2. Laser therapy in Group 1 improved the mouth opening 4.643 mm on average, while in Group 2, the average was 3.71 mm per patient. CONCLUSION: there was effectiveness in both lasers in the pain control and mouth opening of patients.

JUSTIFICATIVA E OBJETIVOS: A dor é um sintoma clínico característico em estágios iniciais do tratamento ortodôntico. O objetivo deste estudo foi rever na literatura o uso da terapia a laser de baixa intensidade na redução da dor durante o tratamento ortodôntico. CONTEÚDO: Uma busca de títulos, resumos e artigos foram realizadas nas bases de dados Pubmed/Medline, Cochrane Library, LILACS e Scielo. Três pesquisadores realizaram de forma independente uma busca utilizando critérios de inclusão e exclusão definidos. Foram incluídos oito ensaios clínicos, sendo que seis deles verificaram redução significativa da dor após uso do laser terapêutico. CONCLUSÃO: Existe evidência científica de que o uso do laser de baixa intensidade diminui a sintomatologia dolorosa após colocação de elásticos ortodônticos e após realização de ajustes ortodônticos durante a movimentação dentária. O seu uso por profissionais da área é uma alternativa viável por apresentar menos efeitos colaterais em relação a analgésicos anti-inflamatórios, sendo bem indicado a pacientes alérgicos, crianças e pacientes com comprometimento sistêmico. No entanto, há a necessidade de investigações científicas adicionais que utilizem protocolos bem definidos.

BACKGROUND AND OBJECTIVES: Pain is a typical symptom during early orthodontic treatment. This study aimed at reviewing the literature on the use of low intensity laser to relieve pain during orthodontic treatment. CONTENTS: Titles, summaries and articles were searched in the following databases: Pubmed/Medline, Cochrane Library, LILACS and Scielo. Three researchers have independently searched using defined inclusion and exclusion criteria. Eight clinical trials were included and six have observed significant pain relief after therapeutic laser. CONCLUSION: There are scientific evidences that low intensity laser decreases pain symptoms during dental movements after the placement of orthodontic elastics and after orthodontic adjustments. Its use by dentists is a feasible alternative for inducing less adverse effects as compared to anti-inflammatory analgesics, being indicated for allergic patients, children and patients with systemic impairment. However, there is the need for further scientific investigations using well-defined protocols.

A tendência da odontologia é a incorporação de métodos menos invasivos com a finalidade de minimizar a dor e o desconforto durante e após as intervenções odontológicas. Por isso, acredita-se que a laserterapia seja uma excelente opção de tratamento, já que apresenta efeitos benéficos para os tecidos irradiados, como ativação da microcirculação, produção de novos capilares, efeitos anti-inflamatórios e analgésicos, além de estímulo ao crescimento e à regeneração celular. O entendimento da interação entre os lasers e os tecidos baseia-se principalmente no entendimento das reações que podem ser induzidas nesses tecidos pela luz laser. Este trabalho se propõe a mostrar a relevância do conhecimento das propriedades físicas do laser, bem como sua interação com os tecidos biológicos, considerando que os efeitos e os mecanismos de ação da luz laser são complexos e alvos de inúmeras pesquisas com vistas a um melhor delineamento de suas formas de aplicação e indicações.

The trend in dentistry is to incorporate less invasive methods to minimize pain and discomfort during and after dental intervention. Therefore, it is believed that laser therapy is an excellent treatment option, since it has beneficial effects for the irradiated tissues, such as activation of microcirculation, production of new capillaries, inflammatory and analgesic effects, in addition to stimulation of growth and cell regeneration. The comprehension of the interaction between lasers and tissue is based mainly on understanding the reactions that can be induced in those tissues by laser. This work intends to show how important it is to know the physical properties of laser as well as its interactions with biological tissues, since its effects and mechanisms of action are complex and are the object of various studies to better understand its forms of application and indications.

Os lasers de baixa potência promovem efeitos biológicos benéficos, de caráter analgésico, antiinflamatório e cicatrizante, por meio de um fenômeno de bioestimulação. A radiação emitida pelo laser terapêutico afeta os processos metabólicos das células-alvo, produzindo efeitos bioestimulantes que resultam na ocorrência de eventos celulares e vasculares, os quais parecem interferir diretamente no processo de reparo. Este trabalho visa estudar o fenômeno da bioestimulação e destacar os principais efeitos bioestimulantes do laser de baixa potência na reparação tecidual.

The wound healing process has always been an excellent subject for researchers. The use of low-power laser on wounds during the postoperative phase has increased the speed of the healing process. It has been implied that low power radiation affects cellular metabolic processes and promotes beneficial biological effects (analgesic, anti-inflammatory, and healing). Laser biostimulation appears to influence the behavior of the repair process. This paper aims at reviewing the most interesting aspects of the use of low-power laser in the tissue-repair process.