Resultados: 141
#1
au:Carvalho, Luiz Paulo de
Filtros
Ordenar por
Página
de 10
Próxima
1.
Changes in Cardiac Morphology and Visceral Fat After the Use of Testosterone Associated with Aerobic Exercise in Wistar Rats Induced Diabetes
Facebook Twitter

Facebook Twitter
- Outras redes sociais
- Google+
- StambleUpon
- CiteULike
- Mendeley
- Outras redes
- Métricas
Perroni-Kudiess, Jéssica
Freitas-da-Silva, Carolina
de-Oliveira-Souza, Rebeca Ferreira
de-Carvalho-Barros, Roseamely Angelica
de-Abreu, Luiz Carlos
Magalhães-Neto, Anibal Magalhaes
Oliveira-Gonçalves, Luis Carlos
Balbino-Lizardo, Frederico
Montes-Fidale, Thiago
Silva, Luípa Michele
Magalhães-de-Abreu, Rusleyd Maria
Martins-Silva, Romeu Paulo
International Journal of Morphology
- Métricas do periódico
SUMMARY: Exercise and anabolic steroids are expected to promote improvements in cardiovascular structure and reduction of visceral fat and, thus, help promote health in hyperglycemic patients. The aim of this study was to verify the influence of aerobic exercise associated with the use of steroids on cardiac structure and visceral fat in hyperglycemic Wistar rats. Methods: Thirty-two young male Wistar rats were divided into four groups: control group (n=8), control with treatment (n=8), diabetic (n=8) and diabetic with treatment (n=8). All animals were subjected to intense aerobic exercise and the animals undergoing treatment received intramuscular testosterone. Body weight, visceral fat and cardiac measurements (weight, length and width) were evaluated. The groups treated with testosterone showed a smaller than expected increase in body weight for food intake. Visceral, perirenal, retroperitoneal and epididymal fats were lower in the treated groups. Heart weight was relatively greater in the treated groups and greater width and length in the untreated groups. The proposed association of testosterone administration with aerobic exercise can provide significant benefits for the metabolism of hyperglycemic individuals.
RESUMEN: Se supone que el ejercicio y los esteroides anabólicos promuevan la mejora de la estructura cardiovascular y la reducción de la grasa visceral y, por tanto, ayuden a promover la salud en pacientes hiperglucémicos. El objetivo de este trabajo fue verificar la influencia del ejercicio aeróbico asociado al uso de esteroides sobre la estructura cardíaca y la grasa visceral en ratas Wistar hiperglucémicas. Treinta y dos ratas Wistar machos jóvenes se dividieron en cuatro grupos: grupo control (n=8), control con tratamiento (n=8), diabético (n=8) y diabético con tratamiento (n=8). Todos los animales se sometieron a ejercicio aeróbico intenso y los animales en tratamiento recibieron testosterona intramuscular. Se evaluaron el peso corporal, la grasa visceral y las medidas del corazón (peso, largo y ancho). Los grupos tratados con testosterona mostraron un aumento menor de lo esperado en el peso corporal según la ingesta dietética. Las grasas visceral, perirrenal, retroperitoneal y epididimaria fueron menores en los grupos tratados. El peso del corazón fue relativamente mayor en los grupos tratados y el mayor ancho y largo en los grupos no tratados. La asociación propuesta de la administración de testosterona con el ejercicio aeróbico puede proporcionar beneficios significativos para el metabolismo de los individuos hiperglucémicos.
2.
Predictive factors for permanent hypoparathyroidism following total thyroidectomy: A retrospective cohort study of 5,671 cases
Facebook Twitter

Facebook Twitter
- Outras redes sociais
- Google+
- StambleUpon
- CiteULike
- Mendeley
- Outras redes
- Métricas
Joaquim, Daniela Tamega
; Kohler, Hugo Fontan
; Vartanian, José Guilherme
; Kowalski, Luiz Paulo
; Carvalho, Genival Barbosa de
.





ABSTRACT Objective: To evaluate the rates of permanent hypoparathyroidism based on demographic variables, patient comorbidities, clinical staging of the disease, surgery performed, and severity of transient hypoparathyroidism. Subjects and methods: This is a retrospective cohort study with patients who underwent total thyroidectomy with or without neck dissection between January 2014 and December 2021. Results: 5,671 patients were analyzed, 966 (17%) presented transient hypoparathyroidism and 106 (1.8%) developed permanent hypoparathyroidism. The logistic regression model analyzing the cohort of patients with transient hypoparathyroidism demonstrates that the number of dissected lymph nodes from the central compartment, immediate postoperative PTH levels, the necessity of postoperative intravenous (IV) calcium supplementation and the duration of IV calcium supplementation are significant predictors. When applied to the original dataset, this model presents a NPV of 1.0000 and a PPV of 0.9594 with an overall accuracy of 0.9624. Conclusion: The incidence of permanent hypoparathyroidism was closely associated with the extent of level VI dissection, particularly regarding the number of lymph nodes removed and whether the dissection was bilateral. Furthermore, the severity of post-operative hypocalcemia was demonstrated by the decrease in PTH levels, as well as the need for and duration of intravenous calcium supplementation.
3.
THE GROWING EVIDENCE OF THE RELATIONSHIP BETWEEN OBESITY AND CANCER AND THE ROLE OF BARIATRIC SURGERY
Facebook Twitter

Facebook Twitter
- Outras redes sociais
- Google+
- StambleUpon
- CiteULike
- Mendeley
- Outras redes
- Métricas
KASSAB, Paulo
; FERRAZ, Álvaro Antônio Bandeira
; MITIDIERI, Anna Clara Hebling
; BERTI, Luiz Vicente
; SANTO, Marco Aurélio
; SZEGO, Tiago
; ZANON, Caio de Carvalho
; CASTRO, Osvaldo Antônio Prado
; FREITAS JUNIOR, Wilson Rodrigues de
; ILIAS, Elias Jirjoss
; MALHEIROS, Carlos Alberto
; VALEZ, Antônio Carlos
; CAMPOS, Antônio Carlos Ligocki
.













ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo)
- Métricas do periódico
ABSTRACT Obesity is recognized as a significant risk factor for various types of cancer. Although the incidence of some types of cancer across various primary sites is decreasing due to specific prevention measures (screening programs, smoking cessation), the incidence of neoplasms in the young population shows a significant increase associated with obesity. There is sufficient evidence to say that bariatric surgery has been shown to significantly lower the risk of developing obesity-associated cancers, which are linked to metabolic dysregulation, chronic low-grade systemic inflammation, and hormonal alterations such as elevated levels of insulin and sex hormones.
RESUMO A obesidade é reconhecida como um fator de risco significativo para vêrios tipos de câncer. Embora a incidência de alguns tipos de câncer de vêrios locais primêrios esteja diminuindo devido a medidas específicas de prevenção (programas de triagem, cessação do tabagismo), a incidência de neoplasias na população jovem mostra um aumento significativo associado à obesidade. Hê evidências suficientes para dizer que a cirurgia bariêtrica demonstrou reduzir significativamente o risco de desenvolver cânceres associados à obesidade, que estão ligados à desregulação metabólica, inflamação sistêmica crônica de baixo grau e alterações hormonais, como níveis elevados de insulina e hormônios sexuais.
4.
AST/ALT ratio: A new approach over old biochemistry tools
Facebook Twitter

Facebook Twitter
- Outras redes sociais
- Google+
- StambleUpon
- CiteULike
- Mendeley
- Outras redes
- Métricas
Machado, Ana L.F.
; Bastos, Laura M.
; Santos, Lucas B.
; Sousa, Mateus F.
; Couto, Marcella P.V.
; Küster, Paulo H.P.
; Oliveira, Luiz E.D.
; Carvalho, Marcelo P.N.
; Leme, Fabiola O. Paes
.









ABSTRACT: This study aimed to evaluate the aspartate transaminase/alanine transaminase (AST/ALT) ratio in healthy dogs and dogs with hepatic and extrahepatic diseases. Twelve different groups of animals were considered in the study: Control, patients with Acute hepatopathy, and Chronic hepatopathy and patients with extrahepatic diseases such as Pyometra, Fractures/trauma, Intoxication/poisoning, Leishmaniosis, Hemoparasitosis, Oncologic, Gastrointestinal, Skin problems and Nephropathy. A retrospective study was made with 509 exams. Hematological and serum biochemical results correlated to the ratio at time zero (M0) and 48 hours (M48) after the first care, allowing for the prediction of the outcome. Animals with Acute hepatopathy showed AST/ALT ratios 84% above the upper limit of the ranges obtained from Control animals. Animals with Chronic hepatopathy showed higher averages than acute. Animals from Pyometra, Fractures/trauma, and Intoxication/poisoning groups showed higher averages of the AST/ALT ratio (2.67, 2.54, 2.21) than those from other groups. The correlation between the AST/ALT ratio in serial assessments showed that when animals double the value of the ratio in 48 hours, they tend to have a 2.5 greater probability of dying.
RESUMO: Este estudo objetivou avaliar a razão AST/ALT em cães saudáveis e cães apresentando doenças hepáticas e extra-hepáticas. Doze grupos diferentes de animais foram considerados no estudo, como um grupo Controle, pacientes com Hepatopatia aguda e Hepatopatia crônica, e grupos com doenças extra-hepáticas como Piometra, Fraturas/trauma, Intoxicação/envenenamento, Leishmaniose, Hemoparasitose, Oncológico, Gastrointestinal, Afecções de pele e Neuropatia. Um estudo retrospectivo foi realizado utilizando 509 exames. Exames hematológicos e bioquímicos foram correlacionados com a razão no tempo zero (M0) e 48 horas (M48) depois do primeiro atendimento, permitindo predizer a consequência. Animais com Hepatopatias agudas apresentaram razão AST/ALT 84% acima do limite inferior das médias observadas nos animais do grupo Controle. Animais com Hepatopatias crônicas apresentaram médias maiores do que Hepatopatias agudas. Animais presentes nos grupos Piometra, Fraturas/trauma e Intoxicação/envenenamento apresentaram as maiores médias da razão AST/ALT (2,67; 2,54; 2,21) quando comparado aos outros grupos. A correlação entre a razão AST/ALT em avaliações seriadas mostraram que, quando o valor da razão dobra em 48 horas, aumenta em 2,5 vezes a probabilidade de morte.
5.
Diretriz de Tomografia Computadorizada e Ressonância Magnética Cardiovascular da Sociedade Brasileira de Cardiologia e do Colégio Brasileiro de Radiologia – 2024
Facebook Twitter

Facebook Twitter
- Outras redes sociais
- Google+
- StambleUpon
- CiteULike
- Mendeley
- Outras redes
- Métricas
Magalhães, Tiago Augusto
; Carneiro, Adriano Camargo de Castro
; Moreira, Valéria de Melo
; Trad, Henrique Simão
; Lopes, Marly Maria Uellendahl
; Cerci, Rodrigo Julio
; Nacif, Marcelo Souto
; Schvartzman, Paulo R.
; Chagas, Antônio Carlos Palandrini
; Costa, Isabela Bispo Santos da Silva
; Schmidt, André
; Shiozaki, Afonso Akio
; Montenegro, Sérgio Tavares
; Piegas, Leopoldo Soares
; Zapparoli, Marcelo
; Nicolau, José Carlos
; Fernandes, Fabio
; Hadlich, Marcelo Souza
; Ghorayeb, Nabil
; Mesquita, Evandro Tinoco
; Gonçalves, Luiz Flávio Galvão
; Ramires, Felix José Alvarez
; Fernandes, Juliano de Lara
; Schwartzmann, Pedro Vellosa
; Rassi, Salvador
; Torreão, Jorge Andion
; Mateos, José Carlos Pachón
; Beck-da-Silva, Luiz
; Silva, Marly Conceição
; Liberato, Gabriela
; Oliveira, Gláucia Maria Moraes de
; Feitosa Filho, Gilson Soares
; Carvalho, Hilka dos Santos Moraes de
; Markman Filho, Brivaldo
; Rocha, Ricardo Paulo de Sousa
; Azevedo Filho, Clerio Francisco de
; Taratsoutchi, Flávio
; Coelho-Filho, Otavio Rizzi
; Kalil Filho, Roberto
; Hajjar, Ludhmila Abrahão
; Ishikawa, Walther Yoshiharu
; Melo, Cíntia Acosta
; Jatene, Ieda Biscegli
; Albuquerque, Andrei Skromov de
; Rimkus, Carolina de Medeiros
; Silva, Paulo Savoia Dias da
; Vieira, Thiago Dieb Ristum
; Jatene, Fabio Biscegli
; Azevedo, Guilherme Sant Anna Antunes de
; Santos, Raul D.
; Monte, Guilherme Urpia
; Ramires, José Antonio Franchini
; Bittencourt, Marcio Sommer
; Avezum, Alvaro
; Silva, Leonardo Sara da
; Abizaid, Alexandre
; Gottlieb, Ilan
; Precoma, Dalton Bertolim
; Szarf, Gilberto
; Sousa, Antônio Carlos Sobral
; Pinto, Ibraim Masciarelli Francisco
; Medeiros, Fábio de Morais
; Caramelli, Bruno
; Parga Filho, José Rodrigues
Santos, Tiago Senra Garcia dos
Prazeres, Carlos Eduardo Elias dos
Lopes, Marcelo Antonio Cartaxo Queiroga
Avila, Luiz Francisco Rodrigues de
Scanavacca, Mauricio Ibrahim
Gowdak, Luis Henrique Wolff
Barberato, Silvio Henrique
Nomura, Cesar Higa
Rochitte, Carlos Eduardo































































6.
Fatal viscerotropic and neurotropic disease after yellow fever vaccine: a rare manifestation leading to diagnosis of severe combined immunodeficiency in an infant
Facebook Twitter

Facebook Twitter
- Outras redes sociais
- Google+
- StambleUpon
- CiteULike
- Mendeley
- Outras redes
- Métricas
Vieira, Lara Jhullian Tolentino
; Goebel, Gabriela Assunção
; Barcelos, Yuri
; Cunha, Luciana Oliveira
; Santos, Luisa Teles Melo
; Romanelli, Roberta Maia de Castro
; Minafra, Fernanda Gontijo
; Carvalho, Andrea Lucchesi de
; Carvalho, Luiz Fernando Andrade de
; Diniz, Lilian Martins Oliveira
.










Revista do Instituto de Medicina Tropical de São Paulo
- Métricas do periódico
ABSTRACT Yellow fever vaccine (YFV) is a live attenuated vaccine that can cause a mild infection in immunocompetent patients. However, it may not be self-limiting in patients with inborn errors of immunity (IEI) and may be the first and most severe presentation in these patients. A 10-month-old female infant sought emergency care presenting fever for three days and diffuse exanthema. She was a previous healthy child of consanguineous parents. The child had received YFV 28 days before the onset of symptoms. Upon hospital admission, petechial rash on the limbs and hepatosplenomegaly were noted on physical exam. Laboratory tests showed thrombocytopenia, increased serum aminotransferases and elevated gamma-glutamyl transferase (GGT) and alkaline phosphatase levels. During hospitalization she developed hypoactivity, drowsiness, and hypotonia. The possibility of viscerotropic and neurotropic vaccine associated disease was suspected and a possible primary immunodeficiency disease considered. The patient was tested for antibodies against the yellow fever virus (MAC ELISA) on serum and cerebrospinal fluid (CSF) samples, showing positive IgM results. Immunophenotyping showed low levels of lymphocytes and absence of T-cell receptor excision circles (TREC), leading to diagnose of severe combined immunodeficiency disease (SCID). Despite treatment, after 35 days of hospitalization, she evolved to cardiorespiratory arrest and death. Serious adverse events after administration of the YFV are rare and associated with neurological or visceral involvement in most cases. The unfavorable outcome highlights the importance of neonatal screening for SCID and the clinical suspicion of primary immunodeficiencies in infants who have serious adverse events to live virus vaccines.
7.
Catálogo Taxonômico da Fauna do Brasil: Setting the baseline knowledge on the animal diversity in Brazil
Facebook Twitter

Facebook Twitter
- Outras redes sociais
- Google+
- StambleUpon
- CiteULike
- Mendeley
- Outras redes
- Métricas
Boeger, Walter A.
; Valim, Michel P.
; Zaher, Hussam
; Rafael, José A.
; Forzza, Rafaela C.
; Percequillo, Alexandre R.
; Serejo, Cristiana S.
; Garraffoni, André R.S.
; Santos, Adalberto J.
Slipinski, Adam
Linzmeier, Adelita M.
Calor, Adolfo R.
Garda, Adrian A.
Kury, Adriano B.
Fernandes, Agatha C.S.
Agudo-Padrón, Aisur I.
Akama, Alberto
Silva Neto, Alberto M. da
Burbano, Alejandro L.
Menezes, Aleksandra
Pereira-Colavite, Alessandre
Anichtchenko, Alexander
Lees, Alexander C.
Bezerra, Alexandra M.R.
Domahovski, Alexandre C.
Pimenta, Alexandre D.
Aleixo, Alexandre L.P.
Marceniuk, Alexandre P.
Paula, Alexandre S. de
Somavilla, Alexandre
Specht, Alexandre
Camargo, Alexssandro
Newton, Alfred F.
Silva, Aline A.S. da
Santos, Aline B. dos
Tassi, Aline D.
Aragão, Allan C.
Santos, Allan P.M.
Migotto, Alvaro E.
Mendes, Amanda C.
Cunha, Amanda
Chagas Júnior, Amazonas
Sousa, Ana A.T. de
Pavan, Ana C.
Almeida, Ana C.S.
Peronti, Ana L.B.G.
Henriques-Oliveira, Ana L.
Prudente, Ana L.
Tourinho, Ana L.
Pes, Ana M.O.
Carmignotto, Ana P.
Wengrat, Ana P.G. da Silva
Dornellas, Ana P.S.
Molin, Anamaria Dal
Puker, Anderson
Morandini, André C.
Ferreira, André da S.
Martins, André L.
Esteves, André M.
Fernandes, André S.
Roza, André S.
Köhler, Andreas
Paladini, Andressa
Andrade, Andrey J. de
Pinto, Ângelo P.
Salles, Anna C. de A.
Gondim, Anne I.
Amaral, Antonia C.Z.
Rondón, Antonio A.A.
Brescovit, Antonio
Lofego, Antônio C.
Marques, Antonio C.
Macedo, Antonio
Andriolo, Artur
Henriques, Augusto L.
Ferreira Júnior, Augusto L.
Lima, Aurino F. de
Barros, Ávyla R. de A.
Brito, Ayrton do R.
Romera, Bárbara L.V.
Vasconcelos, Beatriz M.C. de
Frable, Benjamin W.
Santos, Bernardo F.
Ferraz, Bernardo R.
Rosa, Brunno B.
Sampaio, Brunno H.L.
Bellini, Bruno C.
Clarkson, Bruno
Oliveira, Bruno G. de
Corrêa, Caio C.D.
Martins, Caleb C.
Castro-Guedes, Camila F. de
Souto, Camilla
Bicho, Carla de L.
Cunha, Carlo M.
Barboza, Carlos A. de M.
Lucena, Carlos A.S. de
Barreto, Carlos
Santana, Carlos D.C.M. de
Agne, Carlos E.Q.
Mielke, Carlos G.C.
Caetano, Carlos H.S.
Flechtmann, Carlos H.W.
Lamas, Carlos J.E.
Rocha, Carlos
Mascarenhas, Carolina S.
Margaría, Cecilia B.
Waichert, Cecilia
Digiani, Celina
Haddad, Célio F.B.
Azevedo, Celso O.
Benetti, Cesar J.
Santos, Charles M.D. dos
Bartlett, Charles R.
Bonvicino, Cibele
Ribeiro-Costa, Cibele S.
Santos, Cinthya S.G.
Justino, Cíntia E.L.
Canedo, Clarissa
Bonecker, Claudia C.
Santos, Cláudia P.
Carvalho, Claudio J.B. de
Gonçalves, Clayton C.
Galvão, Cleber
Costa, Cleide
Oliveira, Cléo D.C. de
Schwertner, Cristiano F.
Andrade, Cristiano L.
Pereira, Cristiano M.
Sampaio, Cristiano
Dias, Cristina de O.
Lucena, Daercio A. de A.
Manfio, Daiara
Amorim, Dalton de S.
Queiroz, Dalva L. de
Queiroz, Dalva L. de
Colpani, Daniara
Abbate, Daniel
Aquino, Daniel A.
Burckhardt, Daniel
Cavallari, Daniel C.
Prado, Daniel de C. Schelesky
Praciano, Daniel L.
Basílio, Daniel S.
Bená, Daniela de C.
Toledo, Daniela G.P. de
Takiya, Daniela M.
Fernandes, Daniell R.R.
Ament, Danilo C.
Cordeiro, Danilo P.
Silva, Darliane E.
Pollock, Darren A.
Muniz, David B.
Gibson, David I.
Nogueira, David S.
Marques, Dayse W.A.
Lucatelli, Débora
Garcia, Deivys M.A.
Baêta, Délio
Ferreira, Denise N.M.
Rueda-Ramírez, Diana
Fachin, Diego A.
Souza, Diego de S.
Rodrigues, Diego F.
Pádua, Diego G. de
Barbosa, Diego N.
Dolibaina, Diego R.
Amaral, Diogo C.
Chandler, Donald S.
Maccagnan, Douglas H.B.
Caron, Edilson
Carvalho, Edrielly
Adriano, Edson A.
Abreu Júnior, Edson F. de
Pereira, Edson H.L.
Viegas, Eduarda F.G.
Carneiro, Eduardo
Colley, Eduardo
Eizirik, Eduardo
Santos, Eduardo F. dos
Shimbori, Eduardo M.
Suárez-Morales, Eduardo
Arruda, Eliane P. de
Chiquito, Elisandra A.
Lima, Élison F.B.
Castro, Elizeu B. de
Orlandin, Elton
Nascimento, Elynton A. do
Razzolini, Emanuel
Gama, Emanuel R.R.
Araujo, Enilma M. de
Nishiyama, Eric Y.
Spiessberger, Erich L.
Santos, Érika C.L. dos
Contreras, Eugenia F.
Galati, Eunice A.B.
Oliveira Junior, Evaldo C. de
Gallardo, Fabiana
Hernandes, Fabio A.
Lansac-Tôha, Fábio A.
Pitombo, Fabio B.
Dario, Fabio Di
Santos, Fábio L. dos
Mauro, Fabio
Nascimento, Fabio O. do
Olmos, Fabio
Amaral, Fabio R.
Schunck, Fabio
Godoi, Fábio S. P. de
Machado, Fabrizio M.
Barbo, Fausto E.
Agrain, Federico A.
Ribeiro, Felipe B.
Moreira, Felipe F.F.
Barbosa, Felipe F.
Silva, Fenanda S.
Cavalcanti, Fernanda F.
Straube, Fernando C.
Carbayo, Fernando
Carvalho Filho, Fernando
Zanella, Fernando C.V.
Jacinavicius, Fernando de C.
Farache, Fernando H.A.
Leivas, Fernando
Dias, Fernando M.S.
Mantellato, Fernando
Vaz-de-Mello, Fernando Z.
Gudin, Filipe M.
Albuquerque, Flávio
Molina, Flavio B.
Passos, Flávio D.
Shockley, Floyd W.
Pinheiro, Francielly F.
Mello, Francisco de A.G. de
Nascimento, Francisco E. de L.
Franco, Francisco L.
Oliveira, Francisco L. de
Melo, Francisco T. de V.
Quijano, Freddy R.B.
Salles, Frederico F.
Biffi, Gabriel
Queiroz, Gabriel C.
Bizarro, Gabriel L.
Hrycyna, Gabriela
Leviski, Gabriela
Powell, Gareth S.
Santos, Geane B. dos
Morse, Geoffrey E.
Brown, George
Mattox, George M.T.
Zimbrão, Geraldo
Carvalho, Gervásio S.
Miranda, Gil F.G.
Moraes, Gilberto J. de
Lourido, Gilcélia M.
Neves, Gilmar P.
Moreira, Gilson R.P.
Montingelli, Giovanna G.
Maurício, Giovanni N.
Marconato, Gláucia
Lopez, Guilherme E.L.
Silva, Guilherme L. da
Muricy, Guilherme
Brito, Guilherme R.R.
Garbino, Guilherme S.T.
Flores, Gustavo E.
Graciolli, Gustavo
Libardi, Gustavo S.
Proctor, Heather C.
Gil-Santana, Helcio R.
Varella, Henrique R.
Escalona, Hermes E.
Schmitz, Hermes J.
Rodrigues, Higor D.D.
Galvão Filho, Hilton de C.
Quintino, Hingrid Y.S.
Pinto, Hudson A.
Rainho, Hugo L.
Miyahira, Igor C.
Gonçalves, Igor de S.
Martins, Inês X.
Cardoso, Irene A.
Oliveira, Ismael B. de
Franz, Ismael
Fernandes, Itanna O.
Golfetti, Ivan F.
S. Campos-Filho, Ivanklin
Oliveira, Ivo de S.
Delabie, Jacques H.C.
Oliveira, Jader de
Prando, Jadila S.
Patton, James L.
Bitencourt, Jamille de A.
Silva, Janaina M.
Santos, Jandir C.
Arruda, Janine O.
Valderrama, Jefferson S.
Dalapicolla, Jeronymo
Oliveira, Jéssica P.
Hájek, Jiri
Morselli, João P.
Narita, João P.
Martin, João P.I.
Grazia, Jocélia
McHugh, Joe
Cherem, Jorge J.
Farias Júnior, José A.S.
Fernandes, Jose A.M.
Pacheco, José F.
Birindelli, José L.O.
Rezende, José M.
Avendaño, Jose M.
Duarte, José M. Barbanti
Ribeiro, José R. Inácio
Mermudes, José R.M.
Pujol-Luz, José R.
Santos, Josenilson R. dos
Câmara, Josenir T.
Teixeira, Joyce A.
Prado, Joyce R. do
Botero, Juan P.
Almeida, Julia C.
Kohler, Julia
Gonçalves, Julia P.
Beneti, Julia S.
Donahue, Julian P.
Alvim, Juliana
Almeida, Juliana C.
Segadilha, Juliana L.
Wingert, Juliana M.
Barbosa, Julianna F.
Ferrer, Juliano
Santos, Juliano F. dos
Kuabara, Kamila M.D.
Nascimento, Karine B.
Schoeninger, Karine
Campião, Karla M.
Soares, Karla
Zilch, Kássia
Barão, Kim R.
Teixeira, Larissa
Sousa, Laura D. do N.M. de
Dumas, Leandro L.
Vieira, Leandro M.
Azevedo, Leonardo H.G.
Carvalho, Leonardo S.
Souza, Leonardo S. de
Rocha, Leonardo S.G.
Bernardi, Leopoldo F.O.
Vieira, Letícia M.
Johann, Liana
Salvatierra, Lidianne
Oliveira, Livia de M.
Loureiro, Lourdes M.A. El-moor
Barreto, Luana B.
Barros, Luana M.
Lecci, Lucas
Camargos, Lucas M. de
Lima, Lucas R.C.
Almeida, Lucia M.
Martins, Luciana R.
Marinoni, Luciane
Moura, Luciano de A.
Lima, Luciano
Naka, Luciano N.
Miranda, Lucília S.
Salik, Lucy M.
Bezerra, Luis E.A.
Silveira, Luis F.
Campos, Luiz A.
Castro, Luiz A.S. de
Pinho, Luiz C.
Silveira, Luiz F.L.
Iniesta, Luiz F.M.
Tencatt, Luiz F.C.
Simone, Luiz R.L.
Malabarba, Luiz R.
Cruz, Luiza S. da
Sekerka, Lukas
Barros, Lurdiana D.
Santos, Luziany Q.
Skoracki, Maciej
Correia, Maira A.
Uchoa, Manoel A.
Andrade, Manuella F.G.
Hermes, Marcel G.
Miranda, Marcel S.
Araújo, Marcel S. de
Monné, Marcela L.
Labruna, Marcelo B.
Santis, Marcelo D. de
Duarte, Marcelo
Knoff, Marcelo
Nogueira, Marcelo
Britto, Marcelo R. de
Melo, Marcelo R.S. de
Carvalho, Marcelo R. de
Tavares, Marcelo T.
Kitahara, Marcelo V.
Justo, Marcia C.N.
Botelho, Marcia J.C.
Couri, Márcia S.
Borges-Martins, Márcio
Felix, Márcio
Oliveira, Marcio L. de
Bologna, Marco A.
Gottschalk, Marco S.
Tavares, Marcos D.S.
Lhano, Marcos G.
Bevilaqua, Marcus
Santos, Marcus T.T.
Domingues, Marcus V.
Sallum, Maria A.M.
Digiani, María C.
Santarém, Maria C.A.
Nascimento, Maria C. do
Becerril, María de los A.M.
Santos, Maria E.A. dos
Passos, Maria I. da S. dos
Felippe-Bauer, Maria L.
Cherman, Mariana A.
Terossi, Mariana
Bartz, Marie L.C.
Barbosa, Marina F. de C.
Loeb, Marina V.
Cohn-Haft, Mario
Cupello, Mario
Martins, Marlúcia B.
Christofersen, Martin L.
Bento, Matheus
Rocha, Matheus dos S.
Martins, Maurício L.
Segura, Melissa O.
Cardenas, Melissa Q.
Duarte, Mércia E.
Ivie, Michael A.
Mincarone, Michael M.
Borges, Michela
Monné, Miguel A.
Casagrande, Mirna M.
Fernandez, Monica A.
Piovesan, Mônica
Menezes, Naércio A.
Benaim, Natalia P.
Reategui, Natália S.
Pedro, Natan C.
Pecly, Nathalia H.
Ferreira Júnior, Nelson
Silva Júnior, Nelson J. da
Perioto, Nelson W.
Hamada, Neusa
Degallier, Nicolas
Chao, Ning L.
Ferla, Noeli J.
Mielke, Olaf H.H.
Evangelista, Olivia
Shibatta, Oscar A.
Oliveira, Otto M.P.
Albornoz, Pablo C.L.
Dellapé, Pablo M.
Gonçalves, Pablo R.
Shimabukuro, Paloma H.F.
Grossi, Paschoal
Rodrigues, Patrícia E. da S.
Lima, Patricia O.V.
Velazco, Paul
Santos, Paula B. dos
Araújo, Paula B.
Silva, Paula K.R.
Riccardi, Paula R.
Garcia, Paulo C. de A.
Passos, Paulo G.H.
Corgosinho, Paulo H.C.
Lucinda, Paulo
Costa, Paulo M.S.
Alves, Paulo P.
Roth, Paulo R. de O.
Coelho, Paulo R.S.
Duarte, Paulo R.M.
Carvalho, Pedro F. de
Gnaspini, Pedro
Souza-Dias, Pedro G.B.
Linardi, Pedro M.
Bartholomay, Pedro R.
Demite, Peterson R.
Bulirsch, Petr
Boll, Piter K.
Pereira, Rachel M.M.
Silva, Rafael A.P.F.
Moura, Rafael B. de
Boldrini, Rafael
Silva, Rafaela A. da
Falaschi, Rafaela L.
Cordeiro, Ralf T.S.
Mello, Ramon J.C.L.
Singer, Randal A.
Querino, Ranyse B.
Heleodoro, Raphael A.
Castilho, Raphael de C.
Constantino, Reginaldo
Guedes, Reinaldo C.
Carrenho, Renan
Gomes, Renata S.
Gregorin, Renato
Machado, Renato J.P.
Bérnils, Renato S.
Capellari, Renato S.
Silva, Ricardo B.
Kawada, Ricardo
Dias, Ricardo M.
Siewert, Ricardo
Brugnera, Ricaro
Leschen, Richard A.B.
Constantin, Robert
Robbins, Robert
Pinto, Roberta R.
Reis, Roberto E. dos
Ramos, Robson T. da C.
Cavichioli, Rodney R.
Barros, Rodolfo C. de
Caires, Rodrigo A.
Salvador, Rodrigo B.
Marques, Rodrigo C.
Araújo, Rodrigo C.
Araujo, Rodrigo de O.
Dios, Rodrigo de V.P.
Johnsson, Rodrigo
Feitosa, Rodrigo M.
Hutchings, Roger W.
Lara, Rogéria I.R.
Rossi, Rogério V.
Gerstmeier, Roland
Ochoa, Ronald
Hutchings, Rosa S.G.
Ale-Rocha, Rosaly
Rocha, Rosana M. da
Tidon, Rosana
Brito, Rosangela
Pellens, Roseli
Santos, Sabrina R. dos
Santos, Sandra D. dos
Paiva, Sandra V.
Santos, Sandro
Oliveira, Sarah S. de
Costa, Sávio C.
Gardner, Scott L.
Leal, Sebastián A. Muñoz
Aloquio, Sergio
Bonecker, Sergio L.C.
Bueno, Sergio L. de S.
Almeida, Sérgio M. de
Stampar, Sérgio N.
Andena, Sérgio R.
Posso, Sergio R.
Lima, Sheila P.
Gadelha, Sian de S.
Thiengo, Silvana C.
Cohen, Simone C.
Brandão, Simone N.
Rosa, Simone P.
Ribeiro, Síria L.B.
Letana, Sócrates D.
Santos, Sonia B. dos
Andrade, Sonia C.S.
Dávila, Stephane
Vaz, Stéphanie
Peck, Stewart B.
Christo, Susete W.
Cunha, Suzan B.Z.
Gomes, Suzete R.
Duarte, Tácio
Madeira-Ott, Taís
Marques, Taísa
Roell, Talita
Lima, Tarcilla C. de
Sepulveda, Tatiana A.
Maria, Tatiana F.
Ruschel, Tatiana P.
Rodrigues, Thaiana
Marinho, Thais A.
Almeida, Thaís M. de
Miranda, Thaís P.
Freitas, Thales R.O.
Pereira, Thalles P.L.
Zacca, Thamara
Pacheco, Thaynara L.
Martins, Thiago F.
Alvarenga, Thiago M.
Carvalho, Thiago R. de
Polizei, Thiago T.S.
McElrath, Thomas C.
Henry, Thomas
Pikart, Tiago G.
Porto, Tiago J.
Krolow, Tiago K.
Carvalho, Tiago P.
Lotufo, Tito M. da C.
Caramaschi, Ulisses
Pinheiro, Ulisses dos S.
Pardiñas, Ulyses F.J.
Maia, Valéria C.
Tavares, Valeria
Costa, Valmir A.
Amaral, Vanessa S. do
Silva, Vera C.
Wolff, Vera R. dos S.
Slobodian, Verônica
Silva, Vinícius B. da
Espíndola, Vinicius C.
Costa-Silva, Vinicius da
Bertaco, Vinicius de A.
Padula, Vinícius
Ferreira, Vinicius S.
Silva, Vitor C.P. da
Piacentini, Vítor de Q.
Sandoval-Gómez, Vivian E.
Trevine, Vivian
Sousa, Viviane R.
Sant’Anna, Vivianne B. de
Mathis, Wayne N.
Souza, Wesley de O.
Colombo, Wesley D.
Tomaszewska, Wioletta
Wosiacki, Wolmar B.
Ovando, Ximena M.C.
Leite, Yuri L.R.








ABSTRACT The limited temporal completeness and taxonomic accuracy of species lists, made available in a traditional manner in scientific publications, has always represented a problem. These lists are invariably limited to a few taxonomic groups and do not represent up-to-date knowledge of all species and classifications. In this context, the Brazilian megadiverse fauna is no exception, and the Catálogo Taxonômico da Fauna do Brasil (CTFB) (http://fauna.jbrj.gov.br/), made public in 2015, represents a database on biodiversity anchored on a list of valid and expertly recognized scientific names of animals in Brazil. The CTFB is updated in near real time by a team of more than 800 specialists. By January 1, 2024, the CTFB compiled 133,691 nominal species, with 125,138 that were considered valid. Most of the valid species were arthropods (82.3%, with more than 102,000 species) and chordates (7.69%, with over 11,000 species). These taxa were followed by a cluster composed of Mollusca (3,567 species), Platyhelminthes (2,292 species), Annelida (1,833 species), and Nematoda (1,447 species). All remaining groups had less than 1,000 species reported in Brazil, with Cnidaria (831 species), Porifera (628 species), Rotifera (606 species), and Bryozoa (520 species) representing those with more than 500 species. Analysis of the CTFB database can facilitate and direct efforts towards the discovery of new species in Brazil, but it is also fundamental in providing the best available list of valid nominal species to users, including those in science, health, conservation efforts, and any initiative involving animals. The importance of the CTFB is evidenced by the elevated number of citations in the scientific literature in diverse areas of biology, law, anthropology, education, forensic science, and veterinary science, among others.
8.
Floristic and structural variations in Lowland Atlantic Forests with different histories and their use in conservation planning
Facebook Twitter

Facebook Twitter
- Outras redes sociais
- Google+
- StambleUpon
- CiteULike
- Mendeley
- Outras redes
- Métricas
Oliveira, Jéssica Tetzner de
; Dadalto, Felipe de Carvalho
; Dias, Henrique Machado
; Zorzanelli, João Paulo Fernandes
; Magnago, Luiz Fernando Silva
; Dias, Patrícia Borges
.






ABSTRACT We sought to evaluate the floristic and structural variations between three areas with distinct backgrounds in the Sooretama Biological Reserve, remnantd of Lowland Atlantic Forest in Brazil. For vegetation sampling, 30 transects were established in three different areas: post-pasture (PAS), post-fire (FIR), and preserved (PRE) remnants, totaling a sample area of 0.3ha. All individuals in the woody layer with diameter at breast height ≥ 2.5cm were sampled. Variations in floristic composition were evaluated by means of NMDS, based on the presence or absence of species. There are clear variations between the three areas evaluated, in which the PRE area presents greater species richness, floristic diversity, and basal area, with parameters similar to forests of high diversity in northern Espírito Santo and southern Bahia. The performance of inventories and monitoring of the remnants of Lowland Atlantic Forests in neglected regions are fundamental for planning conservation and enrichment measures of these vegetations
RESUMO Buscamos avaliar as variações florísticas e estruturais entre três áreas com origens distintas na Reserva Biológica de Sooretama. Para amostragem da vegetação, foram estabelecidos 30 transectos em três áreas distintas: pós-pasto (PAS), pós-fogo (FIR) e remanescentes conservados (PRE), totalizando uma área amostral de 0,3ha. Todos os indivíduos da camada lenhosa com diâmetro à altura do peito ≥ 2,5 cm foram amostrados. As variações na composição florística foram avaliadas por meio do NMDS, com base na presença ou ausência de espécies. Há claras variações entre as três áreas avaliadas, sendo que a área do PRE apresenta maior riqueza de espécies, diversidade florística e área basal, com parâmetros semelhantes às florestas de alta diversidade do norte do Espírito Santo e sul da Bahia. A realização de inventários e monitoramento dos remanescentes de Floresta Ombrófila Densa de Terras Baixas em regiões negligenciadas são fundamentais para o planejamento de medidas de conservação e enriquecimento dessas vegetações.
9.
O Impacto Clínico e Econômico do Atraso na Terapia de Reperfusão: Evidências do Mundo Real
Facebook Twitter

Facebook Twitter
- Outras redes sociais
- Google+
- StambleUpon
- CiteULike
- Mendeley
- Outras redes
- Métricas
Gioppatto, Silvio
; Prado, Paulo Sousa
; Elias, Mariana Araújo Lima
; Carvalho, Verônica Homem de
Paiva, Caio Resende da Costa
Alexim, Gustavo de Almeida
Reis, Ricardo Torres Bispo
Nogueira, Ana Claudia Cavalcante
Soares, Alexandre Anderson de Sousa Munhoz
Nadruz, Wilson
Carvalho, Luiz Sergio F. de
Sposito, Andrei C.



Abstract Background: Early reperfusion therapy is acknowledged as the most effective approach for reducing case fatality rates in patients with ST-segment elevation myocardial infarction (STEMI). Objective: Estimate the clinical and economic consequences of delaying reperfusion in patients with STEMI. Methods: This retrospective cohort study evaluated mortality rates and the total expenses incurred by delaying reperfusion therapy among 2622 individuals with STEMI. Costs of in-hospital care and lost productivity due to death or disability were estimated from the perspective of the Brazilian Unified Health System indexed in international dollars (Int$) adjusted by purchase power parity. A p < 0.05 was considered statistically significant. Results: Each additional hour of delay in reperfusion therapy was associated with a 6.2% increase (95% CI: 0.3% to 11.8%, p = 0.032) in the risk of in-hospital mortality. The overall expenses were 45% higher among individuals who received treatment after 9 hours compared to those who were treated within the first 3 hours, primarily driven by in-hospital costs (p = 0.005). A multivariate linear regression model indicated that for every 3-hour delay in thrombolysis, there was an increase in in-hospital costs of Int$497 ± 286 (p = 0.003). Conclusions: The findings of our study offer further evidence that emphasizes the crucial role of prompt reperfusion therapy in saving lives and preserving public health resources. These results underscore the urgent need for implementing a network to manage STEMI cases.
Resumo Fundamento: A terapia de reperfusão precoce é reconhecida como a abordagem mais eficaz para reduzir as taxas de letalidade de casos em pacientes com infarto do miocárdio com supradesnivelamento do segmento ST (IAMCSST). Objetivo: Estimar as consequências clínicas e econômicas do atraso da reperfusão em pacientes com IAMCSST. Métodos: O presente estudo de coorte retrospectivo avaliou as taxas de mortalidade e as despesas totais decorrentes do atraso na terapia de reperfusão em 2.622 indivíduos com IAMCSST. Os custos de cuidados hospitalares e perda de produtividade por morte ou incapacidade foram estimados sob a perspectiva do Sistema Único de Saúde indexado em dólares internacionais (Int$) ajustados pela paridade do poder de compra. Foi considerado estatisticamente significativo p < 0,05. Resultados: Cada hora adicional de atraso na terapia de reperfusão foi associada a um aumento de 6,2% (intervalo de confiança de 95%: 0,3% a 11,8%, p = 0,032) no risco de mortalidade hospitalar. As despesas gerais foram 45% maiores entre os indivíduos que receberam tratamento após 9 horas em comparação com aqueles que foram tratados nas primeiras 3 horas, impulsionados principalmente pelos custos hospitalares (p = 0,005). Um modelo de regressão linear multivariada indicou que para cada 3 horas de atraso na trombólise, houve um aumento nos custos hospitalares de Int$ 497 ± 286 (p = 0,003). Conclusões: Os achados do nosso estudo oferecem mais evidências que enfatizam o papel crucial da terapia de reperfusão imediata no salvamento de vidas e na preservação dos recursos de saúde pública. Estes resultados enfatizam a necessidade urgente de implementação de uma rede para gerir casos de IAMCSST.
10.
Can habits and behaviors predict colonization by community-associated MRSA in patients admitted to a Brazilian hospital?
Facebook Twitter

Facebook Twitter
- Outras redes sociais
- Google+
- StambleUpon
- CiteULike
- Mendeley
- Outras redes
- Métricas
Pinheiro, Marcos Vinicius de Barros
; Cavalcante, Fernanda Sampaio
; Ferreira, Dennis de Carvalho
; Guimarães, Ana Carolina Fonseca
; Ferreira, Adriana Lúcia Pires
; Costa, Claudia Regina da
Santos, Kátia Regina Netto dos
Nouér, Simone Aranha
Rangel, Ana Pereira
Castiñeiras, Anna Carla
Gonzalez, Christiany Moçali
Freire, Joana
Guimarães, Luiz Felipe
Batista, Raquel





Revista do Instituto de Medicina Tropical de São Paulo
- Métricas do periódico
ABSTRACT This study aimed to identify factors associated with colonization by community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) in adult patients admitted to a Brazilian hospital. This is a cross-sectional study, in which patients underwent a nasal swab and were asked about hygiene behavior, habits, and clinical history. Among the 702 patients, 180 (25.6%) had S. aureus and 21 (2.9%) MRSA. The factors associated with MRSA colonization were attending a gym (OR 4.71; 95% CI; 1.42 – 15.06), smoking habit in the last year (OR 2.37; 95% CI; 0.88 – 6.38), previous hospitalization (OR 2.18; CI 95%; 0.89 – 5.25), and shared personal hygiene items (OR 1.99; 95% CI; 0.71 – 5.55). At the time of admission, colonization by CA-MRSA isolates was higher than that found in the general population. This can be an important public health problem, already endemic in hospitals, whose factors such as those associated with habits (smoking cigarettes) and behaviors (team sports practice and activities in gyms) have been strongly highlighted. These findings may help developing infection control policies, allowing targeting patients on higher-risk populations for MRSA colonization.
11.
Impact of L-PRF on pain and healing outcomes in lower third molar surgery: a randomized split-mouth trial
Facebook Twitter

Facebook Twitter
- Outras redes sociais
- Google+
- StambleUpon
- CiteULike
- Mendeley
- Outras redes
- Métricas
MORAES, Raissa Pinheiro
; COSTA, Fábio Wildson Gurgel
; SILVA, Paulo Goberlânio de Barros
; CARVALHO, Francisco Samuel Rodrigues
; PAZ, Jéssica Emanuella Rocha Moura
; MATOS, Gabriel Carvalho
; GURGEL, Marcela Lima
; CETIRA FILHO, Edson Luiz
; SOARES, Eduardo Costa Studart
.









Abstract This study explored the effects of L-PRF on pain, soft tissue healing, periodontal condition, and post-extraction bone repair of mandibular third molars (3Ms). A randomized, prospective, triple-blind, split-mouth clinical trial was conducted with 34 volunteers. Eligible patients were randomly allocated into two treatments: G1 (without L-PRF), G2 (alveoli filled with L-PRF), in which the removal of bilateral 3Ms was performed at the same surgical time. Outcomes were assessed according to a visual analogue scale (pain), soft tissue scoring system (wound healing), periodontal probing of mandibular second molar. Bone repair was determined by volumetric analysis (ITK-SNAP software) and fractal analysis (ImageJ software). An intention-to-treat approach to Statistical analysis was used. L-PRF reduced pain in the 7-day postoperative follow-up (p = 0.019) and not only improved soft tissue healing after 1 month of follow-up (p = 0.021), but also probing depth (distal face) in 3 months postoperatively (p = 0.011). Significant alveolar reduction occurred in 3 months after surgery in both treatments (p < 0.05), however, this was more significant in G1 (p = 0.016). The fractal dimension showed no statistical differences. L-PRF improved postoperative clinical parameters of pain, soft tissue healing, and periodontal condition, suggesting that it has a beneficial effect on preserving the alveolar ridge and accelerating the initial repair process.
12.
Alkaline protease isolate supplemented to reduced crude protein diets improves apparent digestibility but does not support performance in grower-finisher pigs
Facebook Twitter

Facebook Twitter
- Outras redes sociais
- Google+
- StambleUpon
- CiteULike
- Mendeley
- Outras redes
- Métricas
Arndt, Stefani Natâni dos Santos
; Rupolo, Paulo Evaristo
; Azevedo, Liliana Bury de
; Veiga, Bruno Rafael de Melo
; Rodrigues, Gustavo de Amorim
; Carvalho, Silvana Teixeira
; Saraiva, Alysson
; Rocha, Gabriel Cipriano
; Santos, Luan Sousa dos
; Genova, Jansller Luiz
; Carvalho, Paulo Levi de Oliveira
.











ABSTRACT This study aimed to assess an alkaline protease supplemented in diets with and without crude protein (CP) reduction on performance, apparent total tract digestibility (ATTD), blood parameters, and carcass and meat traits in growing-finishing pigs. Forty male pigs (26.2±1.2 kg) were randomly allocated into one of five treatments: negative control (NC, 2% and 1% reduction of CP in grower and finisher phases, respectively, no protease); NC150: NC + 150 mg protease kg−1 diet; NC300: NC + 300 mg protease kg−1 diet; PC: positive control (no CP reduction and protease); and PC300: PC + 300 mg protease kg−1 diet, with eight replicates of one pig/pen. Pigs fed NC showed greater average daily feed intake (ADFI) than pigs fed NC300 or PC and lower ADFI compared to pigs fed NC150. Pigs fed PC had lower ADFI than those fed PC300. Greater average daily gain and gain to feed ratio (G:F) were observed in pigs on NC compared with those on NC300 or NC150 and NC300, respectively. Pigs fed PC showed better G:F than pigs fed PC300. Lower coefficients of ATTD (CTTAD) of dry and organic matter (OM), digestible dry matter (DDM), digestible organic matter (DOM), and digestible protein were observed in growing II pigs fed NC compared with pigs fed NC150 or NC300. Pigs fed NC showed a lower DP compared with PC or NC150. Positive control group showed increased digestible protein compared with NC. Finishing II pigs fed NC showed lower DDM, DOM, CTTAD of OM, and gross energy than pigs fed NC150 or NC300. Pigs fed PC showed greater albumin concentration compared with pigs fed PC300 in finishing II. Pigs fed NC and PC300 showed greater luminosity in the l. thoracis muscle than pigs fed PC. A greater color score was evidenced in the l. thoracis in pigs fed PC compared with pigs fed PC300. The dietary supplementation of isolated alkaline protease and CP-reduced diets improves ATTD without supporting pig performance.
13.
hTERT gene methylation in circulating DNA, tumor, and surrounding tissue in breast cancer: a prospective study
Facebook Twitter

Facebook Twitter
- Outras redes sociais
- Google+
- StambleUpon
- CiteULike
- Mendeley
- Outras redes
- Métricas
Queiroz, Luiz Fernando de
; Silva, Marcelo Soares da Mota e
; Souza, Heitor Siffert Pereira de
; Rosas, Siane Lopes Bittencourt
; Carvalho, Maria da Glória da Costa
.





ABSTRACT BACKGROUND: The human telomerase reverse transcriptase (hTERT) enzyme, encoded by the hTERT gene, synthesizes protective telomeric sequences on chromosomes and plays a fundamental role in cancer formation. Methylation of the hTERT gene has an upregulatory effect, increasing hTERT enzyme synthesis and allowing continuous tumor cell division. OBJECTIVE: In a group of patients with breast cancer, we aimed to analyze the methylation status of hTERT in the tumor, surrounding tissue, and circulating free deoxyribonucleic acid (cfDNA) of blood collected on the day of mastectomy and then approximately one year later. DESIGN AND SETTING: A prospective study was conducted at a university hospital in Rio de Janeiro, Brazil. METHODS: Samples were collected from 15 women with breast cancer on the day of mastectomy and approximately one year postoperatively. cfDNA was analyzed by sodium bisulfite conversion, followed by polymerase chain reaction, electrophoresis, and silver nitrate staining. RESULTS: Methylation of hTERT was detected in the tumors and surrounding tissues of all 15 patients. Five patients displayed hTERT methylation in the cfDNA from the blood of the first collection. Of the ten patients who returned for the second collection, three showed methylation. Two patients with methylation in the first collection did not display methylation in the second collection. One patient with no methylation in the first collection displayed methylation in the second collection, and one patient had a diminished level of methylation in the second collection. CONCLUSION: Only one-third of patients displayed methylation in their cfDNA, which may be related to the success of chemotherapy.
14.
Bone-marrow mononuclear cells and acellular human amniotic membrane improve global cardiac function without inhibition of the NLRP3 Inflammasome in a rat model of heart failure
Facebook Twitter

Facebook Twitter
- Outras redes sociais
- Google+
- StambleUpon
- CiteULike
- Mendeley
- Outras redes
- Métricas
TAKEJIMA, ALINE L.
; MACHADO-JÚNIOR, PAULO ANDRÉ B.
; BLUME, GUSTAVO G.
; SIMEONI, ROSSANA BAGGIO
; FRANCISCO, JULIO CESAR
; TONIAL, MURILO S.
; MARQUEZE, LUIS FELIPE B.
; NORONHA, LUCIA
; OLANDOSKI, MARCIA
; ABDELWAHID, ELTYEB
; CARVALHO, KATHERINE A.T. DE
; PINHO, RICARDO A.
; GUARITA-SOUZA, LUIZ CÉSAR
.













Anais da Academia Brasileira de Ciências
- Métricas do periódico
Abstract Recent studies have suggested that therapies with stem cells and amniotic membrane can modulate the inflammation following an ischemic injury in the heart. This study evaluated the effects of bone-marrow mononuclear cells (BMMC) and acellular human amniotic membrane (AHAM) on cardiac function and NLRP3 complex in a rat model of heart failure.On the 30th day,the echocardiographic showed improvements on ejection fraction and decreased pathological ventricular remodeling on BMMC and AHAM groups.Oxidative stress analysis was similar between the three groups,and the NLRP3 inflammasome activity were not decreased with the therapeutic use of both BMMC and AHAM,in comparison to the control group.
15.
Checklist of the species of the Order Characiformes (Teleostei: Ostariophysi)
Facebook Twitter

Facebook Twitter
- Outras redes sociais
- Google+
- StambleUpon
- CiteULike
- Mendeley
- Outras redes
- Métricas
Toledo-Piza, Mônica
; Baena, Eduardo G.
; Dagosta, Fernando C. P.
; Menezes, Naércio A.
; Ândrade, Marcelo
; Benine, Ricardo C.
; Bertaco, Vinicius A.
; Birindelli, José Luís O.
; Boden, Gert
; Buckup, Paulo A.
; Camelier, Priscila
; Carvalho, Fernando R. de
; Castro, Ricardo M. C.
; Chuctaya, Junior
; Decru, Eva
; Derijst, Eddy
; Dillman, Casey B.
; Ferreira, Katiane M.
; Merxem, Dimitri G.
; Giovannetti, Victor
; Hirschmann, Alice
; Jégu, Michel
; Jerep, Fernando C.
; Langeani, Francisco
; Lima, Flávio C. T.
; Lucena, Carlos A. S.
; Lucena, Zilda Margarete S.
; Malabarba, Luiz R.
; Malabarba, Maria Cláudia S. L.
; Marinho, Manoela M. F.
; Mathubara, Kleber
; Mattox, George M. T.
; Melo, Bruno F.
; Moelants, Tuur
; Moreira, Cristiano R.
; Musschoot, Tobias
; Netto-Ferreira, André L.
; Ota, Rafaela P.
; Oyakawa, Osvaldo T.
; Pavanelli, Carla S.
; Reis, Roberto E.
; Santos, Osmar
; Serra, Jane Piton
; Silva, Gabriel S. C.
; Silva-Oliveira, Cárlison
; Souza-Lima, Rosana
; Vari, Richard P.
; Zanata, Angela M.
.
















































Abstract A checklist of recent and fossil fishes of the Order Characiformes is presented herein and believed to be complete through 2022. A total of 47 collaborators checked and provided information about their taxa of expertise. The list is arranged in alphabetical order by family and then genus and includes all available synonyms. From a total of 3,087 species group names and 527 genus group names, 2,334 species are currently treated as valid, and assigned to 301 genera and 24 families. This total includes 25 species known only from the fossil record, of which 21 are assigned to eight extant families and four are Incertae sedis in Characiformes, but does not include five species based on fossil which were wrongly treated in Characiformes. The status of 79 nominal species remains unresolved. When there are two competing hypotheses about the validity of a name, one of them is chosen and the alternate interpretation is provided in the remark section of that name. Distributional summaries are presented as numbers that correspond to areas for which there is a record of occurrence of the species. A list of unavailable names is provided at the end since some of those names may need additional research to certify their status.
Resumo Uma lista de peixes recentes e fósseis da Ordem Characiformes é apresentada e acredita-se que a lista esteja completa até 2022. Ao todo, 47 colaboradores verificaram e forneceram informações sobre táxons de sua especialidade. A lista está organizada em ordem alfabética por família e em seguida gênero e inclui todos os sinônimos disponíveis. De um total de 3.087 nomes de grupos de espécies e 527 nomes de grupos de gêneros, 2.334 espécies são atualmente tratadas como válidas e atribuídas a 301 gêneros e 24 famílias. Este total inclui 25 espécies fósseis, das quais 21 são incluídas em oito famílias recentes e quatro são Incertae sedis em Characiformes, mas não inclui cinco espécies baseadas em fósseis que foram incorretamente consideradas como Characiformes. O status de 79 espécies nominais permanece não resolvido. Quando há duas hipóteses concorrentes sobre a validade de um nome, uma delas é escolhida e a interpretação alternativa é fornecida na seção de comentários do nome em questão. Dados sobre distribuição geográfica são apresentados através de números que correspondem a regiões para as quais há registro de ocorrência da espécie. Uma lista de nomes indisponíveis foi listada no final do texto, pois alguns desses nomes precisam ser mais bem investigados para certificar seu status.
Exibindo
itens por página
Página
de 10
Próxima
Visualizar estatísticas de
Enviar resultado
Exportar resultados
Sem resultados
Não foram encontrados documentos para sua pesquisa
Glossário e ajuda para busca
Você pode enriquecer sua busca de uma forma muito simples. Use os índices de pesquisa combinados com os conectores (AND ou OR) e especifique cada vez mais sua busca.
Por exemplo, se você deseja buscar artigos sobre
casos de dengue no Brasil em 2015, use:ti:dengue and publication_year:2015 and aff_country:Brasil
Veja abaixo a lista completa de índices de pesquisa que podem ser usados:
Cód. do Índice | Elemento |
---|---|
ti | título do artigo |
au | autor |
kw | palavras-chave do artigo |
subject | assunto (palavras do título, resumo e palavras-chave) |
ab | resumo |
ta | título abreviado da revista (ex. Cad. Saúde Pública) |
journal_title | título completo da revista (ex. Cadernos de Saúde Pública) |
la | código do idioma da publicação (ex. pt - Português, es - Espanhol) |
type | tipo do documento |
pid | identificador da publicação |
publication_year | ano de publicação do artigo |
sponsor | financiador |
aff_country | código do país de afiliação do autor |
aff_institution | instituição de afiliação do autor |
volume | volume do artigo |
issue | número do artigo |
elocation | elocation |
doi | número DOI |
issn | ISSN da revista |
in | código da coleção SciELO (ex. scl - Brasil, col - Colômbia) |
use_license | código da licença de uso do artigo |