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Consensus of the Brazilian Association of Hematology, Hemotherapy and Cellular Therapy (ABHH) and the Brazilian Ministry of Health - General management of blood and blood products on the tests necessary for the release of exceptional medicines for sickle cell disease Hematology ABHH (ABHH
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Lobo, Clarisse
; Araújo, Aderson
; Antunes, Alexandre de Albuquerque
; Pinto, Ana Cristina Silva
; Godinho, Ariadne Carvalho
; Pires, Cassia Silvestre Mariano
; Matheus, Cinthia Cristina
; Albuquerque, Xerez de
; Neves, Daniele Campos Fontes
; Moreno, Fábio de Lima
; Baldanzi, Giorgio
; Siufi, Grazziella Curado
; Miranda, Heloisa Helena Pereira
; Hankins, Jane
; Aragão, Joice
; Braga, Josefina Aparecida Pellegrini
; Martins, Juliana Touguinha Neves
; Souza, Luciana Campos Costa Machado de
; Figueiredo, Maria Stella
; Oliveira, Mirella Rodrigues
; Cardoso, Patricia Santos Resende
; Pinto, Patricia Costa Alves
; Moura, Patricia Gomes
; Cançado, Rodolfo Delfini
; Araujo, Paulo Ivo Cortez de
; Saad, Sara Olalla
; Loggetto, Sandra Regina
; Fonseca, Teresa Cristina Cardoso
.
Hematology, Transfusion and Cell Therapy
- Métricas do periódico
Abstract To date, hydroxyurea is the only effective and safe drug that significantly reduces morbidity and mortality of individuals with Sickle cell disease. Twenty years of real-life experience has demonstrated that hydroxyurea reduces pain attacks, vaso-occlusive events, including acute chest syndrome, the number and duration of hospitalizations and the need for transfusion. The therapeutic success of hydroxyurea is directly linked to access to the drug, the dose used and adherence to treatment which, in part, is correlated to the availability of hydroxyurea. This consensus aims to reduce the number of mandatory exams needed to access the drug, prioritizing the requesting physician's report, without affecting patient safety. date disease reallife real life attacks vasoocclusive vaso occlusive events syndrome transfusion which part physicians physician s report safety
2.
Subtidal benthic marine litter off the coast of Rio de Janeiro, Brazil Janeiro
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Araújo, Fábio Vieira de
; Videla, Eduardo da Silva
; Masi, Bruno Pereira
; Silva, André Luiz Carvalho da
.
ABSTRACT Several studies have reported on the presence of litter on beaches and in the oceans, but this represents the smallest part of the litter that ends up in the sea. Little is known about the litter that settles on the ocean floor, especially near coastal regions. Thus, this study quantified, classified and determined possible sources of subtidal benthic marine litter input off the coast of Rio de Janeiro, Brazil. Different sites were selected in Guanabara Bay, an area with the greatest industrial and population concentration in the state of Rio de Janeiro, and on the coasts of Costa do Sol and Costa Verde, where tourism represents the main economic activity. Material was collected by scuba diving at depths of between 5 and 15 meters at 31 sites distributed among the study areas. A total of 1, 209 items was found, with Guanabara Bay having the highest average concentration (92.40 items/km2), followed by Costa do Sol and Costa Verde (14.15 items/km2 and 9.91 items/km2, respectively). Plastic materials are the most representative solid waste (55.08%), followed by metals (14.97%) and fishing gear (12.48%). Results indicated that local activities affected the composition of the marine litter on Costa do Sol and Costa Verde, whereas in Guanabara Bay, anthropogenic material carried by rivers influenced the marine litter composition at certain locations in addition to local activities. Environmental education actions associated with tourism and fishing activities and better waste management are necessary to minimize the presence of litter in subtidal benthic environments. oceans sea floor regions Thus quantified Janeiro Brazil activity 1 3 areas 20 found 92.40 9240 92 40 (92.4 itemskm2 itemskm , km2 km items/km2) 14.15 1415 14 (14.1 items/km 991 9 91 9.9 respectively. respectively . respectively) 55.08%, 5508 55.08% 55 08 (55.08%) 14.97% 1497 97 (14.97% 12.48%. 1248 12.48% 12 48 (12.48%) environments 2 92.4 924 4 (92. 14.1 141 (14. 99 9. 550 55.08 0 (55.08% 14.97 149 (14.97 124 12.48 (12.48% 92. (92 14. (14 55.0 (55.08 14.9 (14.9 12.4 (12.48 (9 (1 55. (55.0 12. (12.4 ( (55. (12. (55 (12 (5
3.
Prospective, randomized, controlled trial assessing the effects of a driving pressure–limiting strategy for patients with acute respiratory distress syndrome due to community-acquired pneumonia (STAMINA trial): protocol and statistical analysis plan Prospective randomized pressurelimiting pressure limiting communityacquired community acquired STAMINA trial)
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Maia, Israel Silva
; Medrado Jr, Fernando Azevedo
; Tramujas, Lucas
; Tomazini, Bruno Martins
; Oliveira, Júlia Souza
; Sady, Erica Regina Ribeiro
; Barbante, Letícia Galvão
; Nicola, Marina Lazzari
; Gurgel, Rodrigo Magalhães
; Damiani, Lucas Petri
; Negrelli, Karina Leal
; Miranda, Tamiris Abait
; Santucci, Eliana
; Valeis, Nanci
; Laranjeira, Ligia Nasi
; Westphal, Glauco Adrieno
; Fernandes, Ruthy Perotto
; Zandonai, Cássio Luis
; Pincelli, Mariangela Pimentel
; Figueiredo, Rodrigo Cruvinel
; Bustamante, Cíntia Loss Sartori
; Norbin, Luiz Fernando
; Boschi, Emerson
; Lessa, Rafael
; Romano, Marcelo Pereira
; Miura, Mieko Cláudia
; Alencar Filho, Meton Soares de
; Dantas, Vicente Cés de Souza
; Barreto, Priscilla Alves
; Hernandes, Mauro Esteves
; Grion, Cintia Magalhães Carvalho
; Laranjeira, Alexandre Sanches
; Mezzaroba, Ana Luiza
; Bahl, Marina
; Starke, Ana Carolina
; Biondi, Rodrigo Santos
; Dal-Pizzol, Felipe
; Caser, Eliana Bernadete
; Thompson, Marlus Muri
; Padial, Andrea Allegrini
; Veiga, Viviane Cordeiro
; Leite, Rodrigo Thot
; Araújo, Gustavo
; Guimarães, Mário
; Martins, Priscilla de Aquino
; Lacerda, Fábio Holanda
; Hoffmann Filho, Conrado Roberto
; Melro, Livia
; Pacheco, Eduardo
; Ospina-Táscon, Gustavo Adolfo
; Ferreira, Juliana Carvalho
; Freires, Fabricio Jocundo Calado
; Machado, Flávia Ribeiro
; Cavalcanti, Alexandre Biasi
; Zampieri, Fernando Godinho
.
ABSTRACT Background: Driving pressure has been suggested to be the main driver of ventilator-induced lung injury and mortality in observational studies of acute respiratory distress syndrome. Whether a driving pressure-limiting strategy can improve clinical outcomes is unclear. Objective: To describe the protocol and statistical analysis plan that will be used to test whether a driving pressure-limiting strategy including positive end-expiratory pressure titration according to the best respiratory compliance and reduction in tidal volume is superior to a standard strategy involving the use of the ARDSNet low-positive end-expiratory pressure table in terms of increasing the number of ventilator-free days in patients with acute respiratory distress syndrome due to community-acquired pneumonia. Methods: The ventilator STrAtegy for coMmunIty acquired pNeumoniA (STAMINA) study is a randomized, multicenter, open-label trial that compares a driving pressure-limiting strategy to the ARDSnet low-positive end-expiratory pressure table in patients with moderate-to-severe acute respiratory distress syndrome due to community-acquired pneumonia admitted to intensive care units. We expect to recruit 500 patients from 20 Brazilian and 2 Colombian intensive care units. They will be randomized to a driving pressure-limiting strategy group or to a standard strategy using the ARDSNet low-positive end-expiratory pressure table. In the driving pressure-limiting strategy group, positive end-expiratory pressure will be titrated according to the best respiratory system compliance. Outcomes: The primary outcome is the number of ventilator-free days within 28 days. The secondary outcomes are in-hospital and intensive care unit mortality and the need for rescue therapies such as extracorporeal life support, recruitment maneuvers and inhaled nitric oxide. Conclusion: STAMINA is designed to provide evidence on whether a driving pressure-limiting strategy is superior to the ARDSNet low-positive end-expiratory pressure table strategy for increasing the number of ventilator-free days within 28 days in patients with moderate-to-severe acute respiratory distress syndrome. Here, we describe the rationale, design and status of the trial. Background ventilatorinduced induced pressurelimiting limiting unclear Objective endexpiratory end expiratory lowpositive low ventilatorfree free communityacquired community Methods (STAMINA multicenter openlabel open label moderatetosevere moderate severe units 50 Outcomes inhospital hospital support oxide Conclusion Here rationale 5
RESUMO Contexto: Em estudos observacionais sobre a síndrome do desconforto respiratório agudo, sugeriu-se que a driving pressure é o principal fator de lesão pulmonar induzida por ventilador e de mortalidade. Não está claro se uma estratégia de limitação da driving pressure pode melhorar os desfechos clínicos. Objetivo: Descrever o protocolo e o plano de análise estatística que serão usados para testar se uma estratégia de limitação da driving pressure envolvendo a titulação da pressão positiva expiratória final de acordo com a melhor complacência respiratória e a redução do volume corrente é superior a uma estratégia padrão envolvendo o uso da tabela de pressão positiva expiratória final baixa do protocolo ARDSNet, em termos de aumento do número de dias sem ventilador em pacientes com síndrome do desconforto respiratório agudo devido à pneumonia adquirida na comunidade. Métodos: O estudo STAMINA (ventilator STrAtegy for coMmunIty acquired pNeumoniA) é randomizado, multicêntrico e aberto e compara uma estratégia de limitação da driving pressure com a tabela de pressão positiva expiratória final baixa do protocolo ARDSnet em pacientes com síndrome do desconforto respiratório agudo moderada a grave devido à pneumonia adquirida na comunidade internados em unidades de terapia intensiva. Esperamos recrutar 500 pacientes de 20 unidades de terapia intensiva brasileiras e duas colombianas. Eles serão randomizados para um grupo da estratégia de limitação da driving pressure ou para um grupo de estratégia padrão usando a tabela de pressão positiva expiratória final baixa do protocolo ARDSnet. No grupo da estratégia de limitação da driving pressure, a pressão positiva expiratória final será titulada de acordo com a melhor complacência do sistema respiratório. Desfechos: O desfecho primário é o número de dias sem ventilador em 28 dias. Os desfechos secundários são a mortalidade hospitalar e na unidade de terapia intensiva e a necessidade de terapias de resgate, como suporte de vida extracorpóreo, manobras de recrutamento e óxido nítrico inalado. Conclusão: O STAMINA foi projetado para fornecer evidências sobre se uma estratégia de limitação da driving pressure é superior à estratégia da tabela de pressão positiva expiratória final baixa do protocolo ARDSnet para aumentar o número de dias sem ventilador em 28 dias em pacientes com síndrome do desconforto respiratório agudo moderada a grave. Aqui, descrevemos a justificativa, o desenho e o status do estudo. Contexto sugeriuse sugeriu clínicos Objetivo ARDSNet Métodos ventilator pNeumoniA randomizado 50 2 colombianas Desfechos resgate extracorpóreo inalado Conclusão Aqui justificativa 5
4.
Ceratomyxa matosi n. sp. (Myxozoa: Ceratomyxidae) parasitizing the gallbladder of Boulengerella cuvieri (Characiformes: Ctenoluciidae) State of Amapá, Brazilian Amazon n sp Myxozoa (Myxozoa Ceratomyxidae Characiformes (Characiformes Ctenoluciidae Amapá
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Martel, Clemildo Silva
; Souza, Fábio de Abreu e
; Vidal, Samuel Carvalho
; Carvalho, Abthyllane Amaral de
; Hamoy, Igor Guerreiro
; Nascimento, Lilia Suzane de Oliveira
; Videira, Marcela Nunes
.
Revista Brasileira de Parasitologia Veterinária
- Métricas do periódico
Abstract Myxozoa is a class of the Phylum Cnidaria made up of endoparasites from aquatic habitats. The genus Ceratomyxa preferentially infects marine fish, with the gallbladder being the main site parasitized. This study aimed to describe a new species of Ceratomyxa found in this organ in Boulengerella cuvieri using morphological, morphometric characterization and phylogenetic analysis of 18S rDNA gene sequences. Specimens of B. cuvieri were collected, anesthetized, desensitized and biometric measurements were performed. The organs were analyzed under a stereomicroscope and fragments of internal organs were extracted for light microscopy analysis, preserved in 80% ethanol for 18S rDNA gene analysis and fixed in Davidson solution for histological processing. Free spores of Ceratomyxa were observed in the gallbladder, in plasmodia with wave-like movements, with the following dimensions: spore width (24.5 ± 0.4) µm, spore length (5.2 ± 0.3) µm, polar capsule width (1.8 ± 0.2) µm, polar capsule length (2.1 ± 0.3) µm, number of polar tubule turns (4-5) and 100% prevalence. Phylogenetic analysis confirmed that Ceratomyxa matosi n. sp. is a new species, grouped with other freshwater Ceratomyxa species from the Amazon, representing the second description of species of this genus in the state of Amapá. habitats fish parasitized morphological S sequences B collected anesthetized performed 80 processing wavelike wave like movements dimensions 24.5 245 24 5 (24. 0.4 04 0 4 µm 5.2 52 2 (5. 0.3 03 3 1.8 18 1 8 (1. 0.2 02 2.1 21 (2. 45 (4-5 100 prevalence n sp Amazon Amapá 24. (24 0. 5. (5 1. (1 2. (2 (4- 10 ( (4
Resumo Myxozoa é uma classe do Filo Cnidaria, constituída por endoparasitos de habitats aquáticos. O gênero Ceratomyxa infecta, preferencialmente, peixes marinhos, sendo a vesícula biliar o principal sítio parasitado. Este estudo objetivou descrever uma nova espécie de Ceratomyxa encontrada nesse órgão em Boulengerella cuvieri usando caracterização morfológica, morfométrica e análise filogenética de sequências do gene 18S rDNA. Exemplares de B. cuvieri foram coletados, anestesiados, dessensibilizados e realizada aferição biométrica. Os órgãos foram analisados em estereomicroscópio, e fragmentos de órgãos internos foram extraídos para análise por microscopia de luz, preservado em etanol a 80%, para análise do gene 18S rDNA, e fixados em Davidson para processamento histológico. Por meio de ML, foram observados esporos livres de Ceratomyxa na vesícula biliar, em plasmódios com movimentos ondulatórios, com as seguintes dimensões: largura dos esporos (24,5±0,4) µm; comprimento dos esporos (5,2 ± 0,3) µm; largura da cápsula polar (1,8±0,2) µm; comprimento da cápsula polar (2,1 ± 0,3) µm; número de espiras do túbulo polar (4-5) e prevalência de 100%. A análise filogenética confirmou que Ceratomyxa matosi n. sp. é uma nova espécie, agrupando-se com outras espécies de Ceratomyxa de água doce da Amazônia, representando a segunda descrição de uma espécie desse gênero no estado do Amapá. Cnidaria aquáticos infecta preferencialmente marinhos parasitado morfológica S rDNA B coletados anestesiados biométrica estereomicroscópio luz 80 80% histológico ML ondulatórios dimensões 24,5±0,4 24504 24 5 0 4 (24,5±0,4 µm 5,2 52 2 (5, 0,3 03 3 1,8±0,2 1802 1 8 (1,8±0,2 2,1 21 (2, 45 (4-5 100 100% n sp agrupandose agrupando se Amazônia Amapá 24,5±0, 2450 (24,5±0, 5, (5 0, 1,8±0, 180 (1,8±0, 2, (2 (4- 10 24,5±0 245 (24,5±0 ( 1,8±0 18 (1,8±0 (4 24,5± (24,5± 1,8± (1,8± 24,5 (24,5 1,8 (1,8 24, (24, 1, (1, (24 (1
5.
Thermal and mechanical properties of filaments for additive manufacturing
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Abreu, Iago Rodrigues de
; Nascimento Junior, Renato de Sousa
; Fortes, Allef Gabriel Da Silva
; Folkersma, Rudy
; Leitão, Luigi Veloso
; Marques, Fabio Delano Penha
; Sampaio, Arthur Antônio Sousa
; Castro, Layara Lorrana Ribeiro Leite de
; Andrade, Daniella Stepheny Carvalho
; Alves, Tatianny Soares
; Barbosa, Renata
.
Abstract This study explores the development of biodegradable filaments for additive manufacturing, aiming to create membranes for oil and water separation. Using a mixture of poly (lactic acid) and poly (butylene adipate co-terephthalate) (PLA/PBAT) with additives such as zinc oxide, biocide and carnauba wax. The research evaluates the potential of these materials in membrane prototyping for this application. Characterization techniques such as FTIR, XRD, DSC and tensile strength were employed. The results showed that the addition of the additives did not induce the formation of new bands in the FTIR. However, new diffraction peaks appeared in the composites indicating the presence of the zinc oxide. DSC revealed a double peak in melting and crystallization temperatures and the mechanical tests showed significant influence of additives on tensile strength. The composite filaments proved to be suitable for 3D printing, suggesting their applicability in the manufacture of filter membranes for oil and water separation. manufacturing separation lactic acid butylene coterephthalate co terephthalate co-terephthalate PLA/PBAT PLAPBAT PLA PBAT (PLA/PBAT oxide wax application FTIR XRD employed However D printing
6.
Numerical-experimental procedure for predicting fatigue life in SAE AMS 7475-T7351 aluminum alloy considering the effect of stress ratio Numericalexperimental Numerical experimental 7475T7351 T 7475 T7351 7475-T735 7475T735 747 T735 7475-T73 7475T73 74 T73 7475-T7 7475T7 7 T7 7475-T 7475T
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MONTEZUMA, MARCOS FÁBIO V.
; DEUS, ENIO P. DE
; RÜCHERT, CASSIUS OLIVIO F.T.
; CARVALHO, MÁRCIO C. DE
; SILVA FILHO, MARCELO A. E
.
Anais da Academia Brasileira de Ciências
- Métricas do periódico
Abstract This study addresses the prediction of fatigue life in SAE AMS 7475-T7351 aluminum alloys under variable loads, commonly used in the construction of aircraft fuselages. The main objective of the research was to develop a numerical-experimental procedure to analyze crack growth, using the Walker’s approach which considers the effects of the stress ratio R on the fatigue crack growth rate d a / d N, combined with the Finite Element Method and Linear Regression of the Stress Intensity Factor. Observations showed that Walker’s model effectively consolidated fatigue crack propagation data for various stress ratios when applied longitudinally to L-T rolling orientation, due to low dependence of exponent m on R-value in d a / d N equation. Simple averaging of m values effectively calculated Walker’s exponent. The methodology employed experimental tests following ASTM standards for tension, fracture toughness, and fatigue, complemented by Finite Element Method (FEM) simulations. The Walker’s model proved more effective, while the Paris-Erdogan model, which ignores the R effect, resulted in overly conservative service life estimates. The principle of similitude suggests that this methodology could be effective in predicting fatigue life in cases with complex geometries, where calculating the Stress Intensity Factor Fracture parameter is challenging and the Finite Element Method shows efficiency. 7475T7351 T 7475 T7351 7475-T735 loads fuselages numericalexperimental numerical Walkers Walker s LT L orientation Rvalue value equation tension toughness FEM (FEM simulations ParisErdogan Paris Erdogan effect estimates geometries efficiency 7475T735 747 T735 7475-T73 7475T73 74 T73 7475-T7 7475T7 7 T7 7475-T 7475T
7.
Catálogo Taxonômico da Fauna do Brasil: Setting the baseline knowledge on the animal diversity in Brazil Brasil
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Boeger, Walter A.
; Valim, Michel P.
; Zaher, Hussam
; Rafael, José A.
; Forzza, Rafaela C.
; Percequillo, Alexandre R.
; Serejo, Cristiana S.
; Garraffoni, André R.S.
; Santos, Adalberto J.
; Slipinski, Adam
; Linzmeier, Adelita M.
; Calor, Adolfo R.
; Garda, Adrian A.
; Kury, Adriano B.
; Fernandes, Agatha C.S.
; Agudo-Padrón, Aisur I.
; Akama, Alberto
; Silva Neto, Alberto M. da
; Burbano, Alejandro L.
; Menezes, Aleksandra
; Pereira-Colavite, Alessandre
; Anichtchenko, Alexander
; Lees, Alexander C.
; Bezerra, Alexandra M.R.
; Domahovski, Alexandre C.
; Pimenta, Alexandre D.
; Aleixo, Alexandre L.P.
; Marceniuk, Alexandre P.
; Paula, Alexandre S. de
; Somavilla, Alexandre
; Specht, Alexandre
; Camargo, Alexssandro
; Newton, Alfred F.
; Silva, Aline A.S. da
; Santos, Aline B. dos
; Tassi, Aline D.
; Aragão, Allan C.
; Santos, Allan P.M.
; Migotto, Alvaro E.
; Mendes, Amanda C.
; Cunha, Amanda
; Chagas Júnior, Amazonas
; Sousa, Ana A.T. de
; Pavan, Ana C.
; Almeida, Ana C.S.
; Peronti, Ana L.B.G.
; Henriques-Oliveira, Ana L.
; Prudente, Ana L.
; Tourinho, Ana L.
; Pes, Ana M.O.
; Carmignotto, Ana P.
; Wengrat, Ana P.G. da Silva
; Dornellas, Ana P.S.
; Molin, Anamaria Dal
; Puker, Anderson
; Morandini, André C.
; Ferreira, André da S.
; Martins, André L.
; Esteves, André M.
; Fernandes, André S.
; Roza, André S.
; Köhler, Andreas
; Paladini, Andressa
; Andrade, Andrey J. de
; Pinto, Ângelo P.
; Salles, Anna C. de A.
; Gondim, Anne I.
; Amaral, Antonia C.Z.
; Rondón, Antonio A.A.
; Brescovit, Antonio
; Lofego, Antônio C.
; Marques, Antonio C.
; Macedo, Antonio
; Andriolo, Artur
; Henriques, Augusto L.
; Ferreira Júnior, Augusto L.
; Lima, Aurino F. de
; Barros, Ávyla R. de A.
; Brito, Ayrton do R.
; Romera, Bárbara L.V.
; Vasconcelos, Beatriz M.C. de
; Frable, Benjamin W.
; Santos, Bernardo F.
; Ferraz, Bernardo R.
; Rosa, Brunno B.
; Sampaio, Brunno H.L.
; Bellini, Bruno C.
; Clarkson, Bruno
; Oliveira, Bruno G. de
; Corrêa, Caio C.D.
; Martins, Caleb C.
; Castro-Guedes, Camila F. de
; Souto, Camilla
; Bicho, Carla de L.
; Cunha, Carlo M.
; Barboza, Carlos A. de M.
; Lucena, Carlos A.S. de
; Barreto, Carlos
; Santana, Carlos D.C.M. de
; Agne, Carlos E.Q.
; Mielke, Carlos G.C.
; Caetano, Carlos H.S.
; Flechtmann, Carlos H.W.
; Lamas, Carlos J.E.
; Rocha, Carlos
; Mascarenhas, Carolina S.
; Margaría, Cecilia B.
; Waichert, Cecilia
; Digiani, Celina
; Haddad, Célio F.B.
; Azevedo, Celso O.
; Benetti, Cesar J.
; Santos, Charles M.D. dos
; Bartlett, Charles R.
; Bonvicino, Cibele
; Ribeiro-Costa, Cibele S.
; Santos, Cinthya S.G.
; Justino, Cíntia E.L.
; Canedo, Clarissa
; Bonecker, Claudia C.
; Santos, Cláudia P.
; Carvalho, Claudio J.B. de
; Gonçalves, Clayton C.
; Galvão, Cleber
; Costa, Cleide
; Oliveira, Cléo D.C. de
; Schwertner, Cristiano F.
; Andrade, Cristiano L.
; Pereira, Cristiano M.
; Sampaio, Cristiano
; Dias, Cristina de O.
; Lucena, Daercio A. de A.
; Manfio, Daiara
; Amorim, Dalton de S.
; Queiroz, Dalva L. de
; Queiroz, Dalva L. de
; Colpani, Daniara
; Abbate, Daniel
; Aquino, Daniel A.
; Burckhardt, Daniel
; Cavallari, Daniel C.
; Prado, Daniel de C. Schelesky
; Praciano, Daniel L.
; Basílio, Daniel S.
; Bená, Daniela de C.
; Toledo, Daniela G.P. de
; Takiya, Daniela M.
; Fernandes, Daniell R.R.
; Ament, Danilo C.
; Cordeiro, Danilo P.
; Silva, Darliane E.
; Pollock, Darren A.
; Muniz, David B.
; Gibson, David I.
; Nogueira, David S.
; Marques, Dayse W.A.
; Lucatelli, Débora
; Garcia, Deivys M.A.
; Baêta, Délio
; Ferreira, Denise N.M.
; Rueda-Ramírez, Diana
; Fachin, Diego A.
; Souza, Diego de S.
; Rodrigues, Diego F.
; Pádua, Diego G. de
; Barbosa, Diego N.
; Dolibaina, Diego R.
; Amaral, Diogo C.
; Chandler, Donald S.
; Maccagnan, Douglas H.B.
; Caron, Edilson
; Carvalho, Edrielly
; Adriano, Edson A.
; Abreu Júnior, Edson F. de
; Pereira, Edson H.L.
; Viegas, Eduarda F.G.
; Carneiro, Eduardo
; Colley, Eduardo
; Eizirik, Eduardo
; Santos, Eduardo F. dos
; Shimbori, Eduardo M.
; Suárez-Morales, Eduardo
; Arruda, Eliane P. de
; Chiquito, Elisandra A.
; Lima, Élison F.B.
; Castro, Elizeu B. de
; Orlandin, Elton
; Nascimento, Elynton A. do
; Razzolini, Emanuel
; Gama, Emanuel R.R.
; Araujo, Enilma M. de
; Nishiyama, Eric Y.
; Spiessberger, Erich L.
; Santos, Érika C.L. dos
; Contreras, Eugenia F.
; Galati, Eunice A.B.
; Oliveira Junior, Evaldo C. de
; Gallardo, Fabiana
; Hernandes, Fabio A.
; Lansac-Tôha, Fábio A.
; Pitombo, Fabio B.
; Dario, Fabio Di
; Santos, Fábio L. dos
; Mauro, Fabio
; Nascimento, Fabio O. do
; Olmos, Fabio
; Amaral, Fabio R.
; Schunck, Fabio
; Godoi, Fábio S. P. de
; Machado, Fabrizio M.
; Barbo, Fausto E.
; Agrain, Federico A.
; Ribeiro, Felipe B.
; Moreira, Felipe F.F.
; Barbosa, Felipe F.
; Silva, Fenanda S.
; Cavalcanti, Fernanda F.
; Straube, Fernando C.
; Carbayo, Fernando
; Carvalho Filho, Fernando
; Zanella, Fernando C.V.
; Jacinavicius, Fernando de C.
; Farache, Fernando H.A.
; Leivas, Fernando
; Dias, Fernando M.S.
; Mantellato, Fernando
; Vaz-de-Mello, Fernando Z.
; Gudin, Filipe M.
; Albuquerque, Flávio
; Molina, Flavio B.
; Passos, Flávio D.
; Shockley, Floyd W.
; Pinheiro, Francielly F.
; Mello, Francisco de A.G. de
; Nascimento, Francisco E. de L.
; Franco, Francisco L.
; Oliveira, Francisco L. de
; Melo, Francisco T. de V.
; Quijano, Freddy R.B.
; Salles, Frederico F.
; Biffi, Gabriel
; Queiroz, Gabriel C.
; Bizarro, Gabriel L.
; Hrycyna, Gabriela
; Leviski, Gabriela
; Powell, Gareth S.
; Santos, Geane B. dos
; Morse, Geoffrey E.
; Brown, George
; Mattox, George M.T.
; Zimbrão, Geraldo
; Carvalho, Gervásio S.
; Miranda, Gil F.G.
; Moraes, Gilberto J. de
; Lourido, Gilcélia M.
; Neves, Gilmar P.
; Moreira, Gilson R.P.
; Montingelli, Giovanna G.
; Maurício, Giovanni N.
; Marconato, Gláucia
; Lopez, Guilherme E.L.
; Silva, Guilherme L. da
; Muricy, Guilherme
; Brito, Guilherme R.R.
; Garbino, Guilherme S.T.
; Flores, Gustavo E.
; Graciolli, Gustavo
; Libardi, Gustavo S.
; Proctor, Heather C.
; Gil-Santana, Helcio R.
; Varella, Henrique R.
; Escalona, Hermes E.
; Schmitz, Hermes J.
; Rodrigues, Higor D.D.
; Galvão Filho, Hilton de C.
; Quintino, Hingrid Y.S.
; Pinto, Hudson A.
; Rainho, Hugo L.
; Miyahira, Igor C.
; Gonçalves, Igor de S.
; Martins, Inês X.
; Cardoso, Irene A.
; Oliveira, Ismael B. de
; Franz, Ismael
; Fernandes, Itanna O.
; Golfetti, Ivan F.
; S. Campos-Filho, Ivanklin
; Oliveira, Ivo de S.
; Delabie, Jacques H.C.
; Oliveira, Jader de
; Prando, Jadila S.
; Patton, James L.
; Bitencourt, Jamille de A.
; Silva, Janaina M.
; Santos, Jandir C.
; Arruda, Janine O.
; Valderrama, Jefferson S.
; Dalapicolla, Jeronymo
; Oliveira, Jéssica P.
; Hájek, Jiri
; Morselli, João P.
; Narita, João P.
; Martin, João P.I.
; Grazia, Jocélia
; McHugh, Joe
; Cherem, Jorge J.
; Farias Júnior, José A.S.
; Fernandes, Jose A.M.
; Pacheco, José F.
; Birindelli, José L.O.
; Rezende, José M.
; Avendaño, Jose M.
; Duarte, José M. Barbanti
; Ribeiro, José R. Inácio
; Mermudes, José R.M.
; Pujol-Luz, José R.
; Santos, Josenilson R. dos
; Câmara, Josenir T.
; Teixeira, Joyce A.
; Prado, Joyce R. do
; Botero, Juan P.
; Almeida, Julia C.
; Kohler, Julia
; Gonçalves, Julia P.
; Beneti, Julia S.
; Donahue, Julian P.
; Alvim, Juliana
; Almeida, Juliana C.
; Segadilha, Juliana L.
; Wingert, Juliana M.
; Barbosa, Julianna F.
; Ferrer, Juliano
; Santos, Juliano F. dos
; Kuabara, Kamila M.D.
; Nascimento, Karine B.
; Schoeninger, Karine
; Campião, Karla M.
; Soares, Karla
; Zilch, Kássia
; Barão, Kim R.
; Teixeira, Larissa
; Sousa, Laura D. do N.M. de
; Dumas, Leandro L.
; Vieira, Leandro M.
; Azevedo, Leonardo H.G.
; Carvalho, Leonardo S.
; Souza, Leonardo S. de
; Rocha, Leonardo S.G.
; Bernardi, Leopoldo F.O.
; Vieira, Letícia M.
; Johann, Liana
; Salvatierra, Lidianne
; Oliveira, Livia de M.
; Loureiro, Lourdes M.A. El-moor
; Barreto, Luana B.
; Barros, Luana M.
; Lecci, Lucas
; Camargos, Lucas M. de
; Lima, Lucas R.C.
; Almeida, Lucia M.
; Martins, Luciana R.
; Marinoni, Luciane
; Moura, Luciano de A.
; Lima, Luciano
; Naka, Luciano N.
; Miranda, Lucília S.
; Salik, Lucy M.
; Bezerra, Luis E.A.
; Silveira, Luis F.
; Campos, Luiz A.
; Castro, Luiz A.S. de
; Pinho, Luiz C.
; Silveira, Luiz F.L.
; Iniesta, Luiz F.M.
; Tencatt, Luiz F.C.
; Simone, Luiz R.L.
; Malabarba, Luiz R.
; Cruz, Luiza S. da
; Sekerka, Lukas
; Barros, Lurdiana D.
; Santos, Luziany Q.
; Skoracki, Maciej
; Correia, Maira A.
; Uchoa, Manoel A.
; Andrade, Manuella F.G.
; Hermes, Marcel G.
; Miranda, Marcel S.
; Araújo, Marcel S. de
; Monné, Marcela L.
; Labruna, Marcelo B.
; Santis, Marcelo D. de
; Duarte, Marcelo
; Knoff, Marcelo
; Nogueira, Marcelo
; Britto, Marcelo R. de
; Melo, Marcelo R.S. de
; Carvalho, Marcelo R. de
; Tavares, Marcelo T.
; Kitahara, Marcelo V.
; Justo, Marcia C.N.
; Botelho, Marcia J.C.
; Couri, Márcia S.
; Borges-Martins, Márcio
; Felix, Márcio
; Oliveira, Marcio L. de
; Bologna, Marco A.
; Gottschalk, Marco S.
; Tavares, Marcos D.S.
; Lhano, Marcos G.
; Bevilaqua, Marcus
; Santos, Marcus T.T.
; Domingues, Marcus V.
; Sallum, Maria A.M.
; Digiani, María C.
; Santarém, Maria C.A.
; Nascimento, Maria C. do
; Becerril, María de los A.M.
; Santos, Maria E.A. dos
; Passos, Maria I. da S. dos
; Felippe-Bauer, Maria L.
; Cherman, Mariana A.
; Terossi, Mariana
; Bartz, Marie L.C.
; Barbosa, Marina F. de C.
; Loeb, Marina V.
; Cohn-Haft, Mario
; Cupello, Mario
; Martins, Marlúcia B.
; Christofersen, Martin L.
; Bento, Matheus
; Rocha, Matheus dos S.
; Martins, Maurício L.
; Segura, Melissa O.
; Cardenas, Melissa Q.
; Duarte, Mércia E.
; Ivie, Michael A.
; Mincarone, Michael M.
; Borges, Michela
; Monné, Miguel A.
; Casagrande, Mirna M.
; Fernandez, Monica A.
; Piovesan, Mônica
; Menezes, Naércio A.
; Benaim, Natalia P.
; Reategui, Natália S.
; Pedro, Natan C.
; Pecly, Nathalia H.
; Ferreira Júnior, Nelson
; Silva Júnior, Nelson J. da
; Perioto, Nelson W.
; Hamada, Neusa
; Degallier, Nicolas
; Chao, Ning L.
; Ferla, Noeli J.
; Mielke, Olaf H.H.
; Evangelista, Olivia
; Shibatta, Oscar A.
; Oliveira, Otto M.P.
; Albornoz, Pablo C.L.
; Dellapé, Pablo M.
; Gonçalves, Pablo R.
; Shimabukuro, Paloma H.F.
; Grossi, Paschoal
; Rodrigues, Patrícia E. da S.
; Lima, Patricia O.V.
; Velazco, Paul
; Santos, Paula B. dos
; Araújo, Paula B.
; Silva, Paula K.R.
; Riccardi, Paula R.
; Garcia, Paulo C. de A.
; Passos, Paulo G.H.
; Corgosinho, Paulo H.C.
; Lucinda, Paulo
; Costa, Paulo M.S.
; Alves, Paulo P.
; Roth, Paulo R. de O.
; Coelho, Paulo R.S.
; Duarte, Paulo R.M.
; Carvalho, Pedro F. de
; Gnaspini, Pedro
; Souza-Dias, Pedro G.B.
; Linardi, Pedro M.
; Bartholomay, Pedro R.
; Demite, Peterson R.
; Bulirsch, Petr
; Boll, Piter K.
; Pereira, Rachel M.M.
; Silva, Rafael A.P.F.
; Moura, Rafael B. de
; Boldrini, Rafael
; Silva, Rafaela A. da
; Falaschi, Rafaela L.
; Cordeiro, Ralf T.S.
; Mello, Ramon J.C.L.
; Singer, Randal A.
; Querino, Ranyse B.
; Heleodoro, Raphael A.
; Castilho, Raphael de C.
; Constantino, Reginaldo
; Guedes, Reinaldo C.
; Carrenho, Renan
; Gomes, Renata S.
; Gregorin, Renato
; Machado, Renato J.P.
; Bérnils, Renato S.
; Capellari, Renato S.
; Silva, Ricardo B.
; Kawada, Ricardo
; Dias, Ricardo M.
; Siewert, Ricardo
; Brugnera, Ricaro
; Leschen, Richard A.B.
; Constantin, Robert
; Robbins, Robert
; Pinto, Roberta R.
; Reis, Roberto E. dos
; Ramos, Robson T. da C.
; Cavichioli, Rodney R.
; Barros, Rodolfo C. de
; Caires, Rodrigo A.
; Salvador, Rodrigo B.
; Marques, Rodrigo C.
; Araújo, Rodrigo C.
; Araujo, Rodrigo de O.
; Dios, Rodrigo de V.P.
; Johnsson, Rodrigo
; Feitosa, Rodrigo M.
; Hutchings, Roger W.
; Lara, Rogéria I.R.
; Rossi, Rogério V.
; Gerstmeier, Roland
; Ochoa, Ronald
; Hutchings, Rosa S.G.
; Ale-Rocha, Rosaly
; Rocha, Rosana M. da
; Tidon, Rosana
; Brito, Rosangela
; Pellens, Roseli
; Santos, Sabrina R. dos
; Santos, Sandra D. dos
; Paiva, Sandra V.
; Santos, Sandro
; Oliveira, Sarah S. de
; Costa, Sávio C.
; Gardner, Scott L.
; Leal, Sebastián A. Muñoz
; Aloquio, Sergio
; Bonecker, Sergio L.C.
; Bueno, Sergio L. de S.
; Almeida, Sérgio M. de
; Stampar, Sérgio N.
; Andena, Sérgio R.
; Posso, Sergio R.
; Lima, Sheila P.
; Gadelha, Sian de S.
; Thiengo, Silvana C.
; Cohen, Simone C.
; Brandão, Simone N.
; Rosa, Simone P.
; Ribeiro, Síria L.B.
; Letana, Sócrates D.
; Santos, Sonia B. dos
; Andrade, Sonia C.S.
; Dávila, Stephane
; Vaz, Stéphanie
; Peck, Stewart B.
; Christo, Susete W.
; Cunha, Suzan B.Z.
; Gomes, Suzete R.
; Duarte, Tácio
; Madeira-Ott, Taís
; Marques, Taísa
; Roell, Talita
; Lima, Tarcilla C. de
; Sepulveda, Tatiana A.
; Maria, Tatiana F.
; Ruschel, Tatiana P.
; Rodrigues, Thaiana
; Marinho, Thais A.
; Almeida, Thaís M. de
; Miranda, Thaís P.
; Freitas, Thales R.O.
; Pereira, Thalles P.L.
; Zacca, Thamara
; Pacheco, Thaynara L.
; Martins, Thiago F.
; Alvarenga, Thiago M.
; Carvalho, Thiago R. de
; Polizei, Thiago T.S.
; McElrath, Thomas C.
; Henry, Thomas
; Pikart, Tiago G.
; Porto, Tiago J.
; Krolow, Tiago K.
; Carvalho, Tiago P.
; Lotufo, Tito M. da C.
; Caramaschi, Ulisses
; Pinheiro, Ulisses dos S.
; Pardiñas, Ulyses F.J.
; Maia, Valéria C.
; Tavares, Valeria
; Costa, Valmir A.
; Amaral, Vanessa S. do
; Silva, Vera C.
; Wolff, Vera R. dos S.
; Slobodian, Verônica
; Silva, Vinícius B. da
; Espíndola, Vinicius C.
; Costa-Silva, Vinicius da
; Bertaco, Vinicius de A.
; Padula, Vinícius
; Ferreira, Vinicius S.
; Silva, Vitor C.P. da
; Piacentini, Vítor de Q.
; Sandoval-Gómez, Vivian E.
; Trevine, Vivian
; Sousa, Viviane R.
; Sant’Anna, Vivianne B. de
; Mathis, Wayne N.
; Souza, Wesley de O.
; Colombo, Wesley D.
; Tomaszewska, Wioletta
; Wosiacki, Wolmar B.
; Ovando, Ximena M.C.
; Leite, Yuri L.R.
.
ABSTRACT The limited temporal completeness and taxonomic accuracy of species lists, made available in a traditional manner in scientific publications, has always represented a problem. These lists are invariably limited to a few taxonomic groups and do not represent up-to-date knowledge of all species and classifications. In this context, the Brazilian megadiverse fauna is no exception, and the Catálogo Taxonômico da Fauna do Brasil (CTFB) (http://fauna.jbrj.gov.br/), made public in 2015, represents a database on biodiversity anchored on a list of valid and expertly recognized scientific names of animals in Brazil. The CTFB is updated in near real time by a team of more than 800 specialists. By January 1, 2024, the CTFB compiled 133,691 nominal species, with 125,138 that were considered valid. Most of the valid species were arthropods (82.3%, with more than 102,000 species) and chordates (7.69%, with over 11,000 species). These taxa were followed by a cluster composed of Mollusca (3,567 species), Platyhelminthes (2,292 species), Annelida (1,833 species), and Nematoda (1,447 species). All remaining groups had less than 1,000 species reported in Brazil, with Cnidaria (831 species), Porifera (628 species), Rotifera (606 species), and Bryozoa (520 species) representing those with more than 500 species. Analysis of the CTFB database can facilitate and direct efforts towards the discovery of new species in Brazil, but it is also fundamental in providing the best available list of valid nominal species to users, including those in science, health, conservation efforts, and any initiative involving animals. The importance of the CTFB is evidenced by the elevated number of citations in the scientific literature in diverse areas of biology, law, anthropology, education, forensic science, and veterinary science, among others. publications problem uptodate up date classifications context exception (CTFB http//fauna.jbrj.gov.br/, httpfaunajbrjgovbr http //fauna.jbrj.gov.br/ , jbrj gov br (http://fauna.jbrj.gov.br/) 2015 Brazil 80 specialists 1 2024 133691 133 691 133,69 125138 125 138 125,13 82.3%, 823 82 3 (82.3% 102000 102 000 102,00 7.69%, 769 7 69 (7.69% 11000 11 11,00 . 3,567 3567 567 (3,56 2,292 2292 2 292 (2,29 1,833 1833 833 (1,83 1,447 1447 447 (1,44 1000 1,00 831 (83 628 (62 606 (60 520 (52 50 users science health biology law anthropology education others http//fauna.jbrj.gov.br/ faunajbrjgovbr //fauna.jbrj.gov.br (http://fauna.jbrj.gov.br/ 201 8 202 13369 13 133,6 12513 12 125,1 82.3% (82.3 10200 10 00 102,0 7.69% 76 6 (7.69 1100 11,0 3,56 356 56 (3,5 2,29 229 29 (2,2 1,83 183 83 (1,8 1,44 144 44 (1,4 100 1,0 (8 62 (6 60 52 (5 5 http//fauna.jbrj.gov.br (http://fauna.jbrj.gov.br 20 1336 133, 1251 125, 82.3 (82. 1020 0 102, 7.69 (7.6 110 11, 3,5 35 (3, 2,2 22 (2, 1,8 18 (1, 1,4 14 4 ( 82. (82 7.6 (7. 3, (3 2, (2 (1 7. (7
8.
Susceptibility of Elasmopalpus lignosellus (Lepidoptera: Pyralidae) larvae to entomopathogenic nematodes (Rhabditida) Lepidoptera (Lepidoptera Pyralidae Rhabditida (Rhabditida
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Magnabosco, Maria Eduarda Berlatto
; Andaló, Vanessa
; Carvalho, Fábio Janoni
; Faria, Lucas Silva de
.
ABSTRACT The cornstalk borer, Elasmopalpus lignosellus (Lepidoptera: Pyralidae), reduces the productive potential of maize crops and is a difficult pest to manage. A management program using different methods could improve the control of E. lignosellus. Considering the potential of entomopathogenic nematodes (EPN) in reducing insect pest populations in soil, the objective of this study was to evaluate the virulence of these EPN and adjust their concentration for controlling E. lignosellus larvae under laboratory and greenhouse conditions. In the laboratory, the virulence of five EPN populations was tested; then, Heterorhabditis amazonensis MC01 was tested at four concentrations. In the greenhouse, H. amazonensis MC01 was tested at four concentrations and was applied to vessels containing maize plants and six larvae. After five days, mortality was evaluated, and means were compared using Tukey’s test (p-value < 0.05). Heterorhabditis amazonensis MC01 and S. carpocapsae All were equally virulent, reducing the larva population by more than 90%. The concentration of H. amazonensis MC01 that caused the highest mortality of larvae in the laboratory was 182 infective juveniles (IJ) larva-1. In the greenhouse, the nematode was also considered virulent to E. lignosellus since all concentrations tested caused larval mortality greater than 70%. borer Lepidoptera (Lepidoptera Pyralidae, Pyralidae , Pyralidae) manage E (EPN soil conditions then MC MC0 H days evaluated Tukeys Tukey s pvalue p value 0.05. 005 0.05 . 0 05 0.05) S 90 90% 18 IJ (IJ larva1. larva1 1. 1 larva-1 70 70% 00 0.0 9 larva- 7 0.
9.
Diretriz de Tomografia Computadorizada e Ressonância Magnética Cardiovascular da Sociedade Brasileira de Cardiologia e do Colégio Brasileiro de Radiologia – 2024 202 20 2
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Magalhães, Tiago Augusto
; Carneiro, Adriano Camargo de Castro
; Moreira, Valéria de Melo
; Trad, Henrique Simão
; Lopes, Marly Maria Uellendahl
; Cerci, Rodrigo Julio
; Nacif, Marcelo Souto
; Schvartzman, Paulo R.
; Chagas, Antônio Carlos Palandrini
; Costa, Isabela Bispo Santos da Silva
; Schmidt, André
; Shiozaki, Afonso Akio
; Montenegro, Sérgio Tavares
; Piegas, Leopoldo Soares
; Zapparoli, Marcelo
; Nicolau, José Carlos
; Fernandes, Fabio
; Hadlich, Marcelo Souza
; Ghorayeb, Nabil
; Mesquita, Evandro Tinoco
; Gonçalves, Luiz Flávio Galvão
; Ramires, Felix José Alvarez
; Fernandes, Juliano de Lara
; Schwartzmann, Pedro Vellosa
; Rassi, Salvador
; Torreão, Jorge Andion
; Mateos, José Carlos Pachón
; Beck-da-Silva, Luiz
; Silva, Marly Conceição
; Liberato, Gabriela
; Oliveira, Gláucia Maria Moraes de
; Feitosa Filho, Gilson Soares
; Carvalho, Hilka dos Santos Moraes de
; Markman Filho, Brivaldo
; Rocha, Ricardo Paulo de Sousa
; Azevedo Filho, Clerio Francisco de
; Taratsoutchi, Flávio
; Coelho-Filho, Otavio Rizzi
; Kalil Filho, Roberto
; Hajjar, Ludhmila Abrahão
; Ishikawa, Walther Yoshiharu
; Melo, Cíntia Acosta
; Jatene, Ieda Biscegli
; Albuquerque, Andrei Skromov de
; Rimkus, Carolina de Medeiros
; Silva, Paulo Savoia Dias da
; Vieira, Thiago Dieb Ristum
; Jatene, Fabio Biscegli
; Azevedo, Guilherme Sant Anna Antunes de
; Santos, Raul D.
; Monte, Guilherme Urpia
; Ramires, José Antonio Franchini
; Bittencourt, Marcio Sommer
; Avezum, Alvaro
; Silva, Leonardo Sara da
; Abizaid, Alexandre
; Gottlieb, Ilan
; Precoma, Dalton Bertolim
; Szarf, Gilberto
; Sousa, Antônio Carlos Sobral
; Pinto, Ibraim Masciarelli Francisco
; Medeiros, Fábio de Morais
; Caramelli, Bruno
; Parga Filho, José Rodrigues
; Santos, Tiago Senra Garcia dos
; Prazeres, Carlos Eduardo Elias dos
; Lopes, Marcelo Antonio Cartaxo Queiroga
; Avila, Luiz Francisco Rodrigues de
; Scanavacca, Mauricio Ibrahim
; Gowdak, Luis Henrique Wolff
; Barberato, Silvio Henrique
; Nomura, Cesar Higa
; Rochitte, Carlos Eduardo
.
10.
Posicionamento do Departamento de Imagem Cardiovascular da Sociedade Brasileira de Cardiologia sobre o Uso do Strain Miocárdico na Rotina do Cardiologista – 2023 202 20 2
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Almeida, André Luiz Cerqueira
; Melo, Marcelo Dantas Tavares de
; Bihan, David Costa de Souza Le
; Vieira, Marcelo Luiz Campos
; Pena, José Luiz Barros
; Del Castillo, José Maria
; Abensur, Henry
; Hortegal, Renato de Aguiar
; Otto, Maria Estefania Bosco
; Piveta, Rafael Bonafim
; Dantas, Maria Rosa
; Assef, Jorge Eduardo
; Beck, Adenalva Lima de Souza
; Santo, Thais Harada Campos Espirito
; Silva, Tonnison de Oliveira
; Salemi, Vera Maria Cury
; Rocon, Camila
; Lima, Márcio Silva Miguel
; Barberato, Silvio Henrique
; Rodrigues, Ana Clara
; Rabschkowisky, Arnaldo
; Frota, Daniela do Carmo Rassi
; Gripp, Eliza de Almeida
; Barretto, Rodrigo Bellio de Mattos
; Silva, Sandra Marques e
; Cauduro, Sanderson Antonio
; Pinheiro, Aurélio Carvalho
; Araujo, Salustiano Pereira de
; Tressino, Cintia Galhardo
; Silva, Carlos Eduardo Suaide
; Monaco, Claudia Gianini
; Paiva, Marcelo Goulart
; Fisher, Cláudio Henrique
; Alves, Marco Stephan Lofrano
; Grau, Cláudia R. Pinheiro de Castro
; Santos, Maria Veronica Camara dos
; Guimarães, Isabel Cristina Britto
; Morhy, Samira Saady
; Leal, Gabriela Nunes
; Soares, Andressa Mussi
; Cruz, Cecilia Beatriz Bittencourt Viana
; Guimarães Filho, Fabio Villaça
; Assunção, Bruna Morhy Borges Leal
; Fernandes, Rafael Modesto
; Saraiva, Roberto Magalhães
; Tsutsui, Jeane Mike
; Soares, Fábio Luis de Jesus
; Falcão, Sandra Nívea dos Reis Saraiva
; Hotta, Viviane Tiemi
; Armstrong, Anderson da Costa
; Hygidio, Daniel de Andrade
; Miglioranza, Marcelo Haertel
; Camarozano, Ana Cristina
; Lopes, Marly Maria Uellendahl
; Cerci, Rodrigo Julio
; Siqueira, Maria Eduarda Menezes de
; Torreão, Jorge Andion
; Rochitte, Carlos Eduardo
; Felix, Alex
.
Arquivos Brasileiros de Cardiologia
- Métricas do periódico
11.
Growth phenotypes of very low birth weight infants for prediction of neonatal outcomes from a Brazilian cohort: comparison with INTERGROWTH cohort
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Cardoso, Viviane Cunha
; Grandi, Carlos
; Silveira, Rita C.
; Duarte, José Luiz Bandeira
; Viana, Maria Cândida Ferrarez Bouzada
; Ferreira, Daniela Marques de Lima Mota
; Alves Junior, José Mariano Sales
; Embrizi, Laís Furlan
; Gimenes, Carolina Boschi
; Mello e Silva, Nathalia Moura de
; Melo, Fernanda Pegoraro de Godoi
; Venzon, Paulyne Stadler
; Gomez, Dafne Barcala
; Vale, Marynéa Silva do
; Bentlin, Maria Regina
; Barros, Marina Carvalho de Moraes
; Bigélli, Laura Emilia Monteiro
; Diniz, Edna Maria de Albuquerque
; Luz, Jorge Hecker
; Marba, Sérgio Tadeu Martins
; Almeida, João Henrique Carvalho Leme de
; Aragon, Davi Casale
; Carmona, Fabio
.
Abstract Objective: To assess the predictive value of selected growth phenotypes for neonatal morbidity and mortality in preterm infants < 30 weeks and to compare them with INTERGROWTH-21st (IG21). Methods: Retrospective analysis of data from the Brazilian Neonatal Research Network (BNRN) database for very low birth weight (VLBW) at 20 public tertiary-care university hospitals. Outcome: the composite neonatal morbidity and mortality (CNMM) consisted of in-hospital death, oxygen use at 36 weeks, intraventricular hemorrhage grade 3 or 4, and Bell stage 2 or 3 necrotizing enterocolitis. Selected growth phenotypes: small-for-gestational-age (SGA) defined as being < 3rd (SGA3) or 10th (SGA10) percentiles of BW, and large-for-gestational-age (LGA) as being > 97th percentile of BW. Stunting as being < 3rd percentile of the length and wasting as being < 3rd percentile of BMI. Single and multiple log-binomial regression models were fitted to estimate the relative risks of CNMM, comparing them to IG21. Results: 4,072 infants were included. The adjusted relative risks of CNMM associated with selected growth phenotypes were (BNRN/IG21): 1.45 (0.92–2.31)/1.60 (1.27–2.02) for SGA; 0.90 (0.55–1.47)/1.05 (0.55–1.99) for LGA; 1.65 (1.08–2.51)/1.58 (1.28–1.96) for stunting; and 1.48 (1.02–2.17) for wasting. Agreement between the two references was variable. The growth phenotypes had good specificity (>95%) and positive predictive value (70-90%), with poor sensitivity and low negative predictive value. Conclusion: The BNRN phenotypes at birth differed markedly from the IG21 standard and showed poor accuracy in predicting adverse neonatal outcomes. Objective INTERGROWTH21st INTERGROWTHst INTERGROWTH 21st st IG . (IG21) Methods (BNRN VLBW (VLBW tertiarycare tertiary care hospitals Outcome (CNMM inhospital hospital death 4 enterocolitis smallforgestationalage small gestational age SGA (SGA rd SGA3 (SGA3 th SGA10 (SGA10 BW largeforgestationalage large LGA (LGA BMI logbinomial log binomial Results 4072 072 4,07 included BNRN/IG21 BNRNIG21 BNRNIG (BNRN/IG21) 145 1 45 1.4 0.92–2.31/1.60 092231160 0.92–2.31 /1.60 0 92 31 60 (0.92–2.31)/1.6 1.27–2.02 127202 27 02 (1.27–2.02 090 90 0.9 0.55–1.47/1.05 055147105 0.55–1.47 /1.05 55 47 05 (0.55–1.47)/1.0 0.55–1.99 055199 99 (0.55–1.99 165 65 1.6 1.08–2.51/1.58 108251158 1.08–2.51 /1.58 08 51 58 (1.08–2.51)/1.5 1.28–1.96 128196 28 96 (1.28–1.96 stunting 148 48 1.02–2.17 102217 17 (1.02–2.17 variable >95% 95 (>95% 7090%, 7090 70 90% , (70-90%) Conclusion IG2 outcomes (IG21 SGA1 (SGA1 407 07 4,0 BNRN/IG2 BNRNIG2 (BNRN/IG21 14 1. 0.92–2.31/1.6 09223116 092231 0.92–2.3 160 /1.6 9 6 (0.92–2.31)/1. 1.27–2.0 12720 (1.27–2.0 09 0. 0.55–1.47/1.0 05514710 055147 0.55–1.4 105 /1.0 5 (0.55–1.47)/1. 0.55–1.9 05519 (0.55–1.9 16 1.08–2.51/1.5 10825115 108251 1.08–2.5 158 /1.5 (1.08–2.51)/1. 1.28–1.9 12819 (1.28–1.9 1.02–2.1 10221 (1.02–2.1 >95 (>95 7090% 709 7 (70-90% (IG2 40 BNRN/IG (BNRN/IG2 0.92–2.31/1. 0922311 09223 0.92–2. /1. (0.92–2.31)/1 1.27–2. 1272 (1.27–2. 0.55–1.47/1. 0551471 05514 0.55–1. 10 (0.55–1.47)/1 0551 (0.55–1. 1.08–2.51/1. 1082511 10825 1.08–2. 15 (1.08–2.51)/1 1.28–1. 1281 (1.28–1. 1.02–2. 1022 (1.02–2. >9 (>9 (70-90 (IG (BNRN/IG 0.92–2.31/1 0922 0.92–2 /1 (0.92–2.31)/ 1.27–2 127 (1.27–2 0.55–1.47/1 0.55–1 (0.55–1.47)/ 055 (0.55–1 1.08–2.51/1 1082 1.08–2 (1.08–2.51)/ 1.28–1 128 (1.28–1 1.02–2 102 (1.02–2 (> (70-9 0.92–2.31/ 092 0.92– / (0.92–2.31) 1.27– 12 (1.27– 0.55–1.47/ 0.55– (0.55–1.47) (0.55– 1.08–2.51/ 108 1.08– (1.08–2.51) 1.28– (1.28– 1.02– (1.02– ( (70- 0.92 (0.92–2.31 1.27 (1.27 0.55 (0.55–1.47 (0.55 1.08 (1.08–2.51 1.28 (1.28 1.02 (1.02 (70 (0.92–2.3 1.2 (1.2 0.5 (0.55–1.4 (0.5 1.0 (1.08–2.5 (1.0 (7 (0.92–2. (1. (0. (1.08–2. (0.92–2 (1 (0 (1.08–2 (0.92– (1.08– (0.92 (1.08 (0.9
12.
Accurate diagnosis of breast lesions Number 4 – April 2023 202 20 2
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Andrade, Alexandre Vicente de
; Lucena, Clécio Ênio Murta de
; Santos, Danielle Chambô dos
; Pessoa, Eduardo Carvalho
; Mansani, Fabio Postiglione
; Andrade, Felipe Eduardo Martins de
; Tosello, Giuliano Tavares
; Pasqualette, Henrique Alberto Portella
; Couto, Henrique Lima
; Francisco, Jose Luis Esteves
; Costa, Rodrigo Pepe
; Teixeira, Sandra Regina Campos
; Moraes, Thaís Paiva
; Silva Filho, Agnaldo Lopes da
.
Revista Brasileira de Ginecologia e Obstetrícia
- Métricas do periódico
13.
Amplifications of AURKA and AURKB in a Burkitt lymphoma immunodeficiency-associated type: a case report immunodeficiencyassociated immunodeficiency associated type
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Oliveira, Fábio Morato de
; Souza, Vinícius Gonçalves de
; Carvalho, Aparecida de Lourdes
; Lizarte Neto, Fermino Sanches
; Miranda, Carla Silva Siqueira
.
ABSTRACT In equatorial Brazil, the association of Burkitt lymphoma and Epstein–Barr virus manifests at high rates. Here, we report, for the first time, amplifications of aurora kinase genes (AURKA/B) in a patient with a history of periodontal abscess and the presence of a remaining nodule, diagnosed with Burkitt lymphoma and Epstein–Barr virus, and /HIV positive. The patient was a 38-year-old man who presented with a 2-week-old severe jaw pain and a 3-day-old severe bilateral headache. He had a history of human papilloma virus. Interphase FISH analysis showed AURKA and AURKB amplification. The patient’s condition worsened, progressing to death a month after the initial care. Changes in the MYCC and AURKA pathways are directly associated with genomic instability. Thus, MYCC rearrangements and higher expression of AURKA/B may be associated with therapy resistance, highlighting the importance of AURKA/B evaluation in Burkitt lymphoma. Brazil EpsteinBarr Epstein Barr rates Here report time AURKAB B (AURKA/B nodule HIV positive 38yearold yearold 38 year old 2weekold weekold 2 week 3dayold dayold 3 day headache amplification patients s worsened care instability Thus resistance
14.
Surgical treatment of rectal cancer: prospective cohort study about good oncologic results and low rates of abdominoperineal excision cancer
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FAIER, THAIS ANDRESSA SILVA
; QUEIROZ, FABIO LOPES
; LACERDA-FILHO, ANTÔNIO
; PAIVA, RODRIGO ALMEIDA
; FRANÇA NETO, PAULO ROCHA
; CORTES, MARCELO GIUSTI WERNECK
; CARVALHO, ALEXANDRE RIBAS DE
; PEREIRA, BARBARA MARIA TAVARES
.
Revista do Colégio Brasileiro de Cirurgiões
- Métricas do periódico
ABSTRACT Objectives: the purpose of this study was to evaluate the outcome of rectal cancer surgery, in a unit adopting the principles of total mesorectal excision (TME) with a high restorative procedure rate and with a low rate of abdominoperineal excision (APE). Methods: we enrolles patients with extraperitoneal rectal cancer undergoing TME or TME+APE. Patients with mid rectal tumors underwent TME, and patients with tumors of the lower rectum and no criteria for APE underwent TME and intersphincteric resection. Those in which the intersphincteric space was invaded and in those with a free distal margin less than 1cm or a tumor free radial margin were unattainable underwent APE or extralevator abdominoperineal excision (ELAPE). We assessed local recurrence rates, overall survival and involvement of the radial margin. Results: sixty (89.6%) patients underwent TME and seven (10.4%) TME + APE, of which five underwent ELAPE. The local recurrence, in pacientes undergoing TME+LAR, was 3.3% and in patients undergoing APE, 14.3%. The local recurrence rate (p=0.286) or the distant recurrence rate (p=1.000) was similar between groups. There was no involvement of radial margins. Survival after 120 months was similar (p=0.239). Conclusion: rectal malignancies, including those located in the low rectum, may be surgically treated with a low rate of APE without compromising oncological principles and with a low local recurrence rates. Objectives surgery (TME APE. . (APE) Methods TMEAPE TME+APE resection cm ELAPE (ELAPE) rates Results 89.6% 896 89 6 (89.6% 10.4% 104 10 4 (10.4% TMELAR LAR TME+LAR 33 3 3.3 143 14 14.3% p=0.286 p0286 p 0 286 (p=0.286 p=1.000 p1000 1 000 (p=1.000 groups margins 12 p=0.239. p0239 p=0.239 239 (p=0.239) Conclusion malignancies (APE (ELAPE 89.6 8 (89.6 10.4 (10.4 3. 14.3 p=0.28 p028 28 (p=0.28 p=1.00 p100 00 (p=1.00 p023 p=0.23 23 (p=0.239 89. (89. 10. (10. 14. p=0.2 p02 2 (p=0.2 p=1.0 p10 (p=1.0 (p=0.23 (89 (10 p=0. p0 (p=0. p=1. p1 (p=1. (8 (1 p=0 (p=0 p=1 (p=1 ( p= (p= (p
RESUMO Objetivos: o objetivo deste estudo foi avaliar os resultados da cirurgia do câncer de reto, em uma unidade que adota os princípios da excisão total do mesorreto (ETM) com baixa taxa de amputação abdominoperineal (AAP). Métodos: os pacientes com câncer retal extraperitoneal foram submetidos a ETM ou ETM com amputação abdominoperianeal. Pacientes com tumores de reto médio foram submetidos a EMT e pacientes com tumores de reto inferior e sem critérios para AAP foram submetidos a EMT e ressecção interesfincteriana. Aqueles em que o espaço interesfincteriano foi invadido e naqueles com margem distal livre menor que 1cm ou margem radial livre de tumor foram inatingíveis foram submetidos a AAP ou excisão abdominoperineal extraelevadora (ELAPE). Avaliamos as taxas de recorrência local, sobrevida global e envolvimento da margem radial. Resultados: sessenta (89,6%) pacientes realizaram ETM e sete (10,4%) ETM + AAP, dos quais cinco realizaram ELAPE. A recidiva local, em pacientes submetidos a ETM com ressecção anterior baixa, foi de 3,3% e em pacientes submetidos a AAP, 14,3%. A taxa de recorrência local (p=0,286) ou a taxa de recorrência à distância (p=1,000) foi semelhante entre os grupos. Não houve envolvimento das margens radiais. A sobrevida após 120 meses foi semelhante (p=0,239). Conclusão: as neoplasias malignas retais, incluindo aquelas localizadas no reto baixo, podem ser tratadas cirurgicamente com baixo índice de AAP, sem comprometer os princípios oncológicos e com baixo índice de recorrência local. Objetivos (ETM AAP. . (AAP) Métodos abdominoperianeal interesfincteriana cm ELAPE (ELAPE) Resultados 89,6% 896 89 6 (89,6% 10,4% 104 10 4 (10,4% 33 3 3,3 143 14 14,3% p=0,286 p0286 p 0 286 (p=0,286 p=1,000 p1000 1 000 (p=1,000 grupos radiais 12 p=0,239. p0239 p=0,239 239 (p=0,239) Conclusão retais (AAP (ELAPE 89,6 8 (89,6 10,4 (10,4 3, 14,3 p=0,28 p028 28 (p=0,28 p=1,00 p100 00 (p=1,00 p023 p=0,23 23 (p=0,239 89, (89, 10, (10, 14, p=0,2 p02 2 (p=0,2 p=1,0 p10 (p=1,0 (p=0,23 (89 (10 p=0, p0 (p=0, p=1, p1 (p=1, (8 (1 p=0 (p=0 p=1 (p=1 ( p= (p= (p
15.
Pyroligneous extracts with therapeutic action: A technological prospect action
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Moura, Fábio Souza
; Santos, Éder da Silva Rocha
; Varjão, Márcio Thomaz dos Santos
; Santos, Hilda Caroline do Nascimento
; Silva, Andressa Letícia Lopes da
; Soletti, João Inácio
; Carvalho, Sandra Helena Vieira de
; Duarte, Alysson Wagner Fernandes
; Moreira, Magna Suzana Alexandre
; Queiroz, Aline Cavalcanti de
.
Abstract The Pyroligneous extract is a product from the combustion of plant biomass with applications in the fields of health, industrial chemistry, and agriculture. The discovery of new molecules with therapeutic potential and of natural origin continues to be one of the great challenges for research centres around the world. The following work aims to analyze, through a technological prospection, the use of pyroligneous extracts for therapeutic purposes. To carry out the study, searches were carried out in documents deposited in Brazil, Europe, and the United States and searched on platforms specialized in patents. The number of inventions using pyroligneous extract with therapeutic applications is still quite small, however, innovations have been observed for the treatment of diseases of great clinical relevance such as cancer and hypertension. The systematic mapping of innovations is of great importance for the development of new technologies. health chemistry agriculture world analyze prospection purposes study Brazil Europe patents small however hypertension technologies
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