ABSTRACT Purpose To verify the risk of pediatric eating disorders in preschoolers who were born prematurely and relate it to neonatal aspects, breastfeeding and oral habits. Methods Descriptive and longitudinal study. The sample was made up of preschoolers who were born prematurely and who were followed up until 24 months of corrected age. Data collection consisted of analysis of medical records, interviews and application of the Brazilian Infant Feeding Scale (EBAI). Results 19 preschoolers participated, with a mean age of 5.11±0.51, born prematurely (gestational age of 32.05 ± 3.26 weeks), healthy and with normal oral motor function at 2 years of corrected age. The application of the EBAI made it possible to identify the risk of pediatric eating disorders in 31.57% of the sample. There was no difference between the groups with and without risk of pediatric eating disorders regarding neonatal variables, breastfeeding and oral habits. Only the variable feeding time during the neonatal hospitalization period showed a difference between the groups, being higher in children who were not at risk for pediatric eating disorders. Conclusion The risk of pediatric eating disorders occurred in almost a third of pre-school-age premature infants. The dietary transition time during the neonatal hospitalization period was the only variable that showed a difference between the groups with and without risk of pediatric eating disorders. Thus, one may consider that, the moment of introduction of oral feeding and the way in which the diet progresses until the full oral route, during neonatal hospitalization, may be related to eating behavior in other phases of child development. aspects habits study records EBAI. . (EBAI) 1 participated 511051 5 11 0 51 5.11±0.51 gestational 3205 32 05 32.0 326 3 26 3.2 weeks, weeks , weeks) 3157 31 57 31.57 variables preschoolage pre school infants Thus route development (EBAI 51105 5.11±0.5 320 32. 3. 315 31.5 5110 5.11±0. 31. 511 5.11±0 5.11± 5.11 5.1 5.

RESUMO Objetivo verificar o risco de distúrbio alimentar pediátrico em pré-escolares que nasceram prematuros e relacionar com os aspectos neonatais, de aleitamento materno e de hábitos orais. Métodos estudo descritivo e longitudinal. A amostra foi composta por pré-escolares que nasceram prematuros e que foram acompanhados até os 24 meses de idade corrigida. A coleta de dados consistiu em análise de prontuários, entrevista e aplicação da Escala Brasileira de Alimentação Infantil. Resultados participaram 19 pré-escolares, com média de idade de 5 anos e 1 mês, nascidos prematuros (idade gestacional de 32 semanas), saudáveis e com função motora oral normal aos 2 anos de idade corrigida. A aplicação da escala permitiu identificar risco de distúrbio alimentar pediátrico em 31,57% da amostra. Não houve diferença entre os grupos com e sem risco do distúrbio quanto às variáveis neonatais, de aleitamento materno e de hábitos orais. Apenas a variável tempo de transição alimentar no período de internação neonatal apresentou diferença entre os grupos, sendo maior em crianças que não apresentaram risco para o distúrbio. Conclusão O risco de distúrbio alimentar pediátrico ocorreu em quase um terço dos prematuros em idade pré-escolar. O tempo de transição alimentar no período de internação neonatal foi a única variável que apresentou diferença entre os grupos com e sem risco para o distúrbio. Assim, pode-se refletir que o momento de introdução da alimentação oral e a forma de progressão da dieta até a via oral plena na internação neonatal podem ter relação com o comportamento alimentar em outras fases do desenvolvimento infantil. préescolares pré escolares neonatais orais longitudinal corrigida prontuários Infantil préescolares, escolares, mês 3 semanas, semanas , semanas) 3157 31 57 31,57 préescolar. préescolar escolar. escolar pré-escolar Assim podese pode se infantil 315 31,5 31,

Abstract This paper proposes a theoretical reflection on the implications of the social uses and appropriations of the media in the construction of subjectivity. Assuming that subjectivity is a historical and engendered in interactions concept, this paper seeks to point out dimensions in which communication mediated by technical devices can constitute modes of subjectivation. The work is divided into three parts. In the first, we outline what we understand by subject, subjectivity and modes of subjectivation. Next, we show the influence, over time, of mediated communication in the transformation of the symbolic character of social life and in the construction of what we share as reality. Finally, we bring to the scene the context of deep mediatization and the changes in subjectivity. Based on a review of literature and of critical-analytical nature, the work articulates studies of communication, social theory and philosophy to indicate that the conditions of communication reverberate in the conditions of production of ways of life. concept subjectivation parts first subject Next influence time reality Finally criticalanalytical critical analytical nature

Resumo Este artigo propõe uma reflexão teórica sobre as implicações dos usos e apropriações sociais dos meios de comunicação na construção da subjetividade. Partindo do pressuposto de que a subjetividade é uma tessitura histórica e engendrada nas interações, busca-se apontar dimensões nas quais a comunicação mediada por dispositivos técnicos pode constituir modos de subjetivação. Para tanto, o trabalho divide-se em três partes. Na primeira, delineamos o que entendemos por sujeito, subjetividade e modos de subjetivação. Na sequência, mostramos a influência, ao longo do tempo, da comunicação mediada na transformação do caráter simbólico da vida social e na construção do que partilhamos como realidade. Por fim, trazemos à cena o contexto da midiatização profunda e as mudanças na subjetividade. Sustentado em revisão de literatura e de natureza crítico-analítica, o trabalho articula estudos da comunicação, da teoria social e da filosofia para indicar que as condições de comunicação reverberam nas condições de produção dos modos de vida. interações buscase busca se subjetivação tanto dividese divide partes primeira sujeito sequência influência tempo realidade fim críticoanalítica, críticoanalítica crítico analítica, analítica crítico-analítica

ABSTRACT The study aims to evaluate the association between inadequate consumption of antioxidant minerals and plasma lipoprotein concentrations in adolescents. We conducted a cross-sectional study that evaluated sociodemographic and anthropometric data, information on intake of magnesium, selenium and zinc and lipid profile. Student's t-test was used to compare means between the groups and logistic regression to verify the strength of the association between the independent variables and lipid profile. Inadequate zinc consumption was associated with a higher chance of low HDL-c levels and lower chance of hypertriglyceridemia and high LDL-c levels. Inadequate selenium intake was associated with a lower chance of high total cholesterol and of high triglyceride concentrations and a higher chance of low HDL-c levels. Inadequate magnesium consumption was associated with a higher chance of high cholesterol and triglyceride levels, a lower chance of high LDL-c levels and with a higher chance of low HDL-c. We observed an association between inadequate consumption of magnesium, zinc and selenium and changes in the lipid profile of adolescents.

RESUMEN El estudio tiene como objetivo evaluar la asociación entre el consumo inadecuado de minerales antioxidantes y las concentraciones plasmáticas de lipoproteínas en adolescentes. Estudio transversal que evaluó datos sociodemográficos y antropométricos, información sobre ingesta de magnesiom selenio y zinc y perfil lipídico. Se utilizó la prueba t de Student para comparar medias entre los grupos y regresión logística para verificar la fuerza de la asociación entre las variables independientes y el perfil lipídico. El consumo inadecuado de zinc se asoció con una mayor probabilidad de niveles bajos de HDL-c y una menor probabilidad de hipertrigliceridemia y niveles altos de LDL-c. La ingesta inadecuada de selenio se asoció con una menor probabilidad de colesterol total alto y de altas concentraciones de triglicéridos y una mayor probabilidad de niveles bajos de HDL-c. El consumo inadecuado de magnesio se asoció con una mayor probabilidad de niveles altos de colesterol y triglicéridos, una menor probabilidad de niveles altos de LDL-c y una mayor probabilidad de niveles bajos de HDL-c. El estudio muestra una asociación entre el consumo inadecuado de magnesio, zinc y selenio y los cambios en el perfil lipídico de los adolescentes.

Resumo A partir da reflexão sobre os aspectos constituintes da epistemologia contemporânea em ciências sociais, este artigo busca delinear perspectivas e desafios aos estudos da mediatização na comunicação. Por meio de uma revisão bibliográfica, apresentamos, inicialmente, um breve panorama histórico da constituição das ciências sociais, a fim de apontar especificidades da pesquisa social e da pesquisa em comunicação e desafios impostos pelo fenômeno da mediatização aos estudos comunicacionais. Nesse trajeto, o texto revela que o percurso de constituição histórica e institucionalização das ciências sociais sinaliza pistas para enfrentamento dos possíveis obstáculos à elaboração do conceito e, quiçá, de uma teoria da mediatização.

Abstract From the reflection on the constituent aspects of contemporary epistemology in social sciences, this article seeks to delineate perspectives and challenges to the studies of mediatization in communication. Through a bibliographic review, we present, initially, a brief historical overview of the constitution of the social sciences, in order to point out the specificities of social research and communication research and challenges imposed by the phenomenon of mediatization to communicational studies. In this way, the text reveals that the course of historical constitution and institutionalization of the social sciences points out clues for facing possible obstacles to the elaboration of the concept and, perhaps, of a theory of mediatization.

BACKGROUND: Statins are used as cholesterol-lowering drugs and may also have direct antimicrobial effects. OBJECTIVE: To evaluate synergic interactions between simvastatin and both amphotericin B and fluconazole, against environmental strains of Cryptococcus neoformans isolated from captive birds’ droppings. DESIGNAND SETTING: Experimental study conducted at Federal University of Piauí, Parnaíba, in collaboration with Federal University of Triângulo Mineiro, Uberaba, Brazil. METHODS: Statin susceptibility tests of Cryptococcus neoformans samples were performed as prescribed in standards. Interactions of simvastatin with amphotericin and fluconazole were evaluated using the checkerboard microdilution method. Presence of these interactions was quantitatively detected through determining the fractional inhibitory concentration index (FICI). RESULTS: Isolates of Cryptococcus neoformans were obtained from 30 of the 206 samples of dry bird excreta (14.5%) that were collected from pet shops and houses. Ten isolates were selected for susceptibility tests. All of them were susceptible to amphotericin and fluconazole. All presented minimum inhibitory concentration (MIC) > 128 µg/ml and, thus, were resistant in vitro to simvastatin. An in vitro synergic effect was shown through combined testing of amphotericin B and simvastatin, such that six isolates (60%) presented FICI < 0.500. Two isolates showed considerable reductions in MIC, from 1 µg/ml to 0.250 µg/ml. No synergic effect was observed through combining fluconazole and simvastatin. CONCLUSION: These results demonstrate that simvastatin should be considered to be a therapeutic alternative, capable of potentiating the action of amphotericin B. However, further studies are necessary to clarify the real effect of simvastatin as an antifungal agent.

Abstract The coronavirus disease 2019 (COVID-19) outbreak has created unprecedent challenges for healthcare systems worldwide. Oncology services have been reorganized to decrease the risk of nosocomial acquisition of SARS-CoV-2, but changes in treatment pathways and follow-up cancer care can result in patients receiving suboptimal or delayed care. Herein, we describe a cross-sectional nested cohort study conducted to evaluate delays in care for patients with head and neck cancer (HNC) in post-treatment follow-up or palliative care during the COVID-19 pandemic in Northeast Brazil and its impact on health outcomes. Information was extracted from medical records and supplemented by telephone interviews. We compared the following health outcomes: self-perception of anxiety or sadness, fear of COVID-19 infection, cancer-related complications during social isolation, self-medication, diagnosis of COVID-19, and death between patients with and without delayed cancer care. The Mann-Whitney U test was used to compare distributions of continuous variables and the Fisher exact test was used for categorical variables. Thirty-one HNC patients were included in the study, and no case of confirmed SARS-CoV-2 was found. Delayed cancer care due to restriction in health services was reported in 58.1% of cases, and there was no report of telemedicine use during the COVID-19 outbreak. Cancer-related complications during the COVID-19 pandemic were described for most patients (67.7%) and included pain or discomfort, swelling, and dyspnea. Eight (25.8%) patients reported use of prescribed morphine or codeine to manage pain and six (19.4%) patients reported self-medication with over-the-counter (OTC) non-steroidal anti-inflammatory drugs (NSAIDs). We found an association between delayed HNC care and the use of self-medication (p = 0.028). This study indicated that patients with delayed HNC care during the COVID-19 outbreak are more likely to use self-medication with NSAIDs for pain management. Better strategies to follow HNC patients in socioeconomically disadvantaged communities need to be discussed and implemented.

RESUMO Objetivo: Avaliar a funcionalidade de indivíduos idosos e jovens com dor lombar crônica. Método: Foram avaliados 83 indivíduos, sendo 42 idosos (Grupo controle: 22 e Grupo dor lombar: 20) e 41 jovens (Grupo controle: 20 e Grupo dor lombar: 21). Para avaliação da capacidade funcional, foram utilizados os testes Timed Up and Go (TUG), sentar e levantar de uma cadeira 5 vezes (Five Times Sit-to-Stand - FTSTS), o teste da caminhada dos seis minutos (TC6min) e sentar e levantar do solo (TSL). Resultados: Não houve diferença na capacidade funcional dos jovens entre os grupos (p > 0,05). Contudo, quando a análise é ajustada para a covariável “IMC”, o Grupo dor lombar apresentou pior desempenho no teste TSL (p = 0,004). No grupo de idosos, foi observado pior desempenho no Grupo dor lombar no teste TSL (p = 0,001). Após o ajuste pela variável “IMC”, observou-se diferença estatística nas condições do teste TSL, assim como no TC6min (p < 0,05) . Conclusão: Idosos com dor lombar crônica apresentaram pior desempenho funcional e o teste TSL foi o mais discriminativo para avaliação funcional de indivíduos com dor lombar crônica. Nível de Evidência III, Estudo Retrospectivo Comparativo.

ABSTRACT Objective: The objective of this study was to analyze the functional status of adult and older adult individuals with lower back pain . Methods: Eighty-three individuals were recruited, 42 older adults (20 with lower back pain and 22 control group) and 41 younger adults (21 with lower back pain and 20 control group). Functional capacity was assessed using the following tests: Timed Up and Go (TUG), Five Times Sit-to-Stand (FTSTS), six-minute walking test (SMWT), and sitting-rising test (SRT) . Results: In the younger adults, there was no difference in functional capacity between the groups (p>0.05). On the other hand, when statistical analysis was adjusted using body mass index (BMI) as a covariate, the lower back pain group performed more poorly on the SRT (p<0.004). Furthermore, poorer physical capacity was seen in the older adults with back pain via the SRT test (p=0.001), and when the BMI was adjusted, a statistical difference was seen in the SRT as well as the SMWT (p<0.05) . Conclusion: Older individuals with lower back pain have poorer physical performance, and the sitting-rising test is the most discerning for assessment of functional status in individuals with lower back pain. Level of Evidence III, Retrospective Comparative Study.

SUMMARY Introduction: Group B streptococcus (GBS) or Streptococcus agalactiae can colonize the gastrointestinal and genitourinary tracts and has been considered one of the most important risk factors for the development of neonatal disease. The present study evaluated the antimicrobial susceptibility of GBS isolates from pregnant women who were attended at a public health service in Northern Paraná, Brazil. Methods: A descriptive analytical cross-sectional study was performed with 544 pregnant women, at ≥ 35 weeks of gestation. One hundred and thirty-six GBS isolates from pregnant women were tested for antimicrobial susceptibility. Results: All of the GBS isolates showed susceptibility to the drug that is most frequently used for intrapartum prophylaxis: penicillin. Resistance to clindamycin and erythromycin was detected, thus decreasing the options of prophylaxis in women who are allergic to penicillin. Conclusions: Additional studies should be conducted to increase the knowledge of GBS sensitivity profile to antimicrobials in other health centers.

Resumo Este artigo objetivou analisar o universo de significação da alimentação fora do lar de um grupo de homens idosos, articulando elementos de disciplinas da Saúde e das Ciências Sociais e Humanas. Os homens moravam sozinhos e eram frequentadores do Programa de Extensão Grupo Renascer, da Universidade Federal do Estado do Rio de Janeiro. A partir de observações diretas, entrevistas informais e entrevistas em profundidade e utilizando-se da Análise do Discurso, partindo de uma perspectiva de mosaico cultural, analisou-se esse espaço social da alimentação fora do lar como promotor de diferentes estilos de interação e coesão social para esse grupo. Verificou-se que aposentadoria, viuvez e saída dos filhos de casa estão relacionadas às mudanças nas práticas alimentares do grupo. E que, além do desinteresse em preparar as refeições, havia uma busca por ambientes mais propícios a novas relações sociais. O comer fora de casa assume um sentido de socialização como representando uma inclusão no mundo globalizado. Frequentar praças de alimentação, especialmente quando se está sem companhia, se mostrou mais interessante para os idosos do que despender tempo na cozinha para o preparo de uma refeição que não seria compartilhada. Tanto comer fora quanto comprar comida fora para comer em casa motivaram novos tipos de relacionamentos sociais nessa população.

AbstractThis article aimed to analyze the significance of eating out for a group of elderly men, combining elements of the Health, Social and Human Sciences. The men lived alone and attended the Grupo Renascer Extension Program of the Universidade Federal do Estado do Rio de Janeiro. Through direct observation, informal and in-depth interviews and Discourse Analysis, the social role of eating out as a promoter of different types of interaction and social cohesion for this group was evaluated. It was found that retirement, widowhood and children leaving home were related to changes in the dietary practices of the group. As well as a lack of interest in preparing meals, there was a desire to find environments that were more conducive to new social relations. Eating out represents a sense of socialization, representing inclusion in the globalized world. Eating in food courts, especially when alone, was more attractive to the elderly men than spending time in the kitchen preparing a meal that would not be shared. Eating out or buying take-out food to eat at home led to new types of social relationships for this population.