ABSTRACT Objective: To evaluate the correlation between blood alcohol levels and the severity of injuries assessed by the Injury Severity Score (ISS) in patients who were victims of traffic accidents admitted to the Hospital das Clínicas of the Faculty of Medicine of the University of São Paulo (HCFMUSP). Methods: Cross-sectional study carried out between July 2018 and June 2019, at the Central Emergency Room of the Hospital das Clínicas of the Faculty of Medicine of the University of São Paulo (PSC-HCFMUSP). A total of 172 hospitalized patients victims of traffic accidents were included in this study. Blood samples were analyzed by the FMUSP Toxicology Laboratory. Results: 36 patients (20.9%) had positive BAC (≥ 0.2 g/L) with a mean of 1.21 g/L. Overall, patients had a mean age of 37.2 years old, and 136 (79.1%) were men. The ISS of the total casuistry was 15.6; regarding the external cause, the motorcycle was ranked first with 100 cases (58.1%), and drivers were the majority with 57.4% of the sample. Conclusion: There was no correlation between the severity of the injuries and the blood alcohol levels of traffic accident victims admitted to a reference hospital. Level of Evidence II, Cross-Sectional Study. Objective (ISS HCFMUSP. HCFMUSP . (HCFMUSP) Methods Crosssectional Cross sectional 201 2019 PSCHCFMUSP. PSCHCFMUSP PSC (PSC-HCFMUSP) 17 Laboratory Results 3 20.9% 209 20 9 (20.9% ≥ ( 02 0 2 0. g/L gL g L 121 1 21 1.2 Overall 372 37 37. old 13 79.1% 791 79 (79.1% men 15.6 156 15 6 cause 10 58.1%, 581 58.1% , 58 (58.1%) 574 57 4 57.4 sample Conclusion hospital II CrossSectional Sectional Study (HCFMUSP (PSC-HCFMUSP 20.9 (20.9 12 1. 79.1 7 (79.1 15. 58.1 5 (58.1% 57. 20. (20. 79. (79. 58. (58.1 (20 (79 (58. (2 (7 (58 (5

RESUMO Objetivo: Avaliar a correlação entre a alcoolemia e a gravidade das lesões avaliadas pelo Índice de Gravidade da Lesão ( Injury Severity Score* – ISS) em vítimas de acidentes de trânsito internadas no Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HC-FMUSP).* Método: Estudo transversal realizado entre julho de 2018 e junho de 2019, no Pronto Socorro Central do HC-FMUSP. Foram incluídas 172 vítimas de acidentes de trânsito. Amostras de sangue foram analisadas pelo Laboratório de Toxicologia da FMUSP. Resultados: 36 pacientes (20,9%) apresentaram alcoolemia positiva (≥ 0,2 g/L), com valor médio de 1,21 g/L. No geral, os pacientes tinham uma idade média de 37,2 anos, e 136 (79,1%) eram homens. O ISS da casuística total foi 15,6; quanto à causa externa, a motocicleta ficou em primeiro lugar com 100 casos (58,1%); e os condutores foram prevalentes entre as vítimas (57,4%). Conclusão: Não houve correlação entre a gravidade das lesões e a alcoolemia das vítimas de acidente de trânsito internadas em um hospital de referência. Nível de Evidência II, Estudo de Corte Transversal. Objetivo Score HCFMUSP.* HCFMUSP HC FMUSP .* (HC-FMUSP). Método 201 2019 HCFMUSP. HC-FMUSP 17 Resultados 3 20,9% 209 20 9 (20,9% ≥ 02 0 2 0, g/L, gL g/L , g L g/L) 121 1 21 1,2 geral 372 37 37, anos 13 79,1% 791 79 (79,1% homens 15,6 156 15 6 externa 10 58,1% 581 58 (58,1%) 57,4%. 574 57,4% . 57 4 (57,4%) Conclusão referência II Transversal (HC-FMUSP) 20,9 (20,9 12 1, 79,1 7 (79,1 15, 58,1 5 (58,1% 57,4 (57,4% (HC-FMUSP 20, (20, 79, (79, 58, (58,1 57, (57,4 (20 (79 (58, (57, (2 (7 (58 (57 (5

Abstract Context: Vehicle driving depends on the integration of motor, visual, and cognitive skills to respond appropriately to different situations that occur in traffic. Objectives: To analyze a model of performance predictor for braking time in the driving simulator, using a battery of tests divided by gender. Methods: Selected were 100 male drivers with a mean age of 72.6 ± 5.7 years. Sociode-mographic variables, braking time in the driving simulator, and motor, visual, and cognitive skills were evaluated. Results: Comparing genders, men were older than women (p = 0.002) and had longer driving times (p = 0.001). Men had more strength in hand grip (p ≤ 0.001). In the linear regression analysis, the model explained 68 % of the braking time in men and 50.8 % in women. In the stepwise multiple linear regression analysis, the variable that remained in the model was the strength of the right plantar flexors, which explained 13 % of the braking time in women and men, and the cognitive variables explained 38.9 %. Conclusion: Sociodemographic, motor, visual, and cognitive variables, explained a substantial portion of the variability in braking time for both older women and men, the specific variables driving this performance differed between the sexes. For older women, factors such as muscle strength emerged as critical determinants of braking ability, highlighting the importance of physical health in maintaining driving skills. On the other hand, cognitive conditions emerged as the primary predictor of braking performance in older men, underscoring the role of mental acuity and decision-making processes in safe driving. Context motor visual traffic Objectives simulator gender Methods 10 726 72 6 72. 57 5 7 5. years Sociodemographic Sociode mographic evaluated Results genders p 0.002 0002 0 002 0.001. 0001 0.001 . 001 0.001) analysis 508 50 8 50. flexors 1 389 38 9 38. Conclusion sexes ability decisionmaking decision making 0.00 000 00 3 0.0 0.

Abstract Context: Many studies show the importance of evaluating the adaptation time of subjects in a virtual driving environment, looking forwards to a response as closest as a possible real vehicle. Objectives: This study aimed to identify and analyze the adaptation to the driving simulator in older adults and middle-aged adults with and without a distraction, and a secondary aim was to identify predictors of safe performance for older adults’ drives. Design: Male and female middle-aged adults (n = 62, age = 30.3 ± 7.1 years) and older adults (n = 102, age = 70.4 ± 5.8 years) were evaluated for braking time performance in a driving simulator; cognition performance assessment included the Mini-Mental State Examination; motor evaluation included ankle flexor muscle strength with the isokinetic dynamometer and handgrip strength; the postural balance was evaluated with Timed Up and Go test, with and without a cognitive distraction task. Results: Older adults (men and women) and middle-aged adult women require more time to adapt to the driving simulator. The distractor increases the adaptation time for all groups. The main predictors of braking time for older women are age, muscle strength, and postural balance associated with distraction, and for older men, muscle strength. Conclusions: Age, sex, and distractor interfere in the adaptation of the virtual task of driving in a simulator. The evaluation model developed with multi-domains demonstrated the ability to predict which skills are related to braking time with and without the presence of the distractor. Context environment vehicle Objectives middleaged middle aged drives Design n 62 303 30 3 30. 71 7 1 7. years 102 704 70 4 70. 58 5 8 5. MiniMental Mini Mental Examination test Results men groups Conclusions Age sex multidomains multi domains 6 10

OBJECTIVES: This study sought to analyze the extent of motor adaptation in ankle plantar flexors and dorsiflexors among older drivers during clinical isokinetic testing. METHODS: One hundred older adults (70.4±5.7 years) participated in two bilateral ankle plantar flexor and dorsiflexor isokinetic assessments at 30°/sec. Peak torque (PTQ), PTQ adjusted for body weight (PTQ/BW), and total work (TW) were analyzed. RESULTS: On the dominant side, PTQ/BW and TW were significantly greater for the second plantar flexion test than were those for the first such test (p<0.001), whereas PTQ, PTQ/BW, and TW (p<0.001) were significantly greater for the second dorsiflexion test than were those for the first such test. On the non-dominant side, plantar flexion PTQ and TW were significantly lower for the second test than were those for the first test (p<0.001). CONCLUSION: Older drivers demonstrated better performance with the dominant limb on the second test. The low variability in test execution showed the existence of a motor adaptation effect for the tested movements, despite the short recovery period between the assessments.

INTRODUÇÃO Apesar dos inúmeros benefícios para a saúde humana e considerando o aumento da corrida como exercício, atividade mundialmente popular, este tipo de esporte pode ser a causa de uma série de diferentes lesões. O pé, tornozelo e parte inferior da perna compreendem quase 40% das lesões. No entanto, a etiologia destas lesões permanece mal compreendida. OBJETIVO: investigar as causas do aparecimento da lesão de esforço em corredores. MÉTODOS: Uma busca sistemática foi realizada nas seguintes bases de dados: Bireme, PubMed e PEDro, selecionando-se ensaios clínicos, casos controle, estudos prospectivos e de corte transversal. RESULTADOS: A pesquisa através dos descritores rendeu 324 referências. Usando critérios de inclusão pré-definidos (estudos de casos, ensaios clínicos, estudos prospectivos e estudos transversais que abordavam adultos corredores indivíduos, amador ou profissional) permaneceram 68 artigos; 24 citações foram excluídos depois de ler o título, e 35 foram excluídos após a leitura do resumo e do texto integral. Portanto nove estudos que preencheram os critérios de análise foram incluídos. CONCLUSÃO: A etiologia das lesões de esforço em corredores é multifatorial. Esta revisão mostrou que a distância, tipo de solo e calçados, bem como uma história de lesões prévias, alterações biomecânicas como o aumento da dorsiflexão e eversão do tornozelo, e uma maior flexão do joelho são fatores de risco que influenciam a ocorrência dessas lesões.

INTRODUCTION: In spite of the numerous benefits to human health and given the increase of running as an exercise that has become popular worldwide, this type of sport may be the cause of a number of different injuries. The foot, ankle and lower leg comprise almost 40% of the injuries. However, the etiology of these types of injury is still not completely understood. OBJECTIVE: To investigate the causes of the onset of overuse injury in runners. METHODS: A systematic search of the electronic database was made: Bireme, Pubmed and PEDro, which were selected that addressed clinical trials, control cases, prospective and cross-sectional studies. RESULTS: The search through the descriptors yielded 324 references. Using our predefined inclusion criteria (case studies, clinical trials, prospective studies and cross studies that addressed adult runners, amateur or professional) 68 articles remained; 24 citations were excluded after reading the title, and 35 were excluded after reading the abstract and the full text. Therefore nine studies that met the criteria for analysis were included. CONCLUSION: The etiology of overuse injuries in runners is multifactorial. This review showed that distance, soil type and footwear, as well as a history of previous injuries, biomechanical changes such as increased dorsiflexion and eversion ankle, and greater knee flexion are risk factors that influence the occurrence of these injuries.

OBJETIVO: Estimar os valores de limiar de dor por pressão (LDP) dos músculos craniocervicais de mulheres com migrânea episódica (ME) n=15 e crônica (MC) n=14, e em voluntários controles saudáveis (C) n=15. MÉTODO: O LDP foi obtido bilateralmente por examinadores cegos através da algometria de pressão nos seguintes músculos: frontal, temporal, masseter, trapézio e esternocleidomastóideo. Para análise estatística foi utilizada a ANOVA (p<0.05). RESULTADOS: Em relação aos controles, pacientes com ME apresentaram redução significativa do LDP para os músculos: frontal (ME: 2,01±0,67 vs. C: 2,85±0,71), temporal posterior bilateralmente (direito e esquerdo, respectivamente) (ME: 2,72±0,89 vs. C: 3,36±0,72 e ME: 2,60±1,00 vs. C: 3,35±0,85), trapézio superior bilateralmente (ME: 2,69±1,00 vs. C: 3,49±0,83 e ME: 2,54±0,93 vs. C: 3,32±0,97) e mulheres com MC: no músculo frontal bilateralmente (MC: 2,16±0,52 vs. C: 2,79±0,71 e MC: 2,01±0,67 vs. C: 2,85±0,71) e trapézio superior (MC: 2,66±0,84 vs. C: 3,32±0,97). Entretanto não foram verificadas diferenças entre os valores de LDP entre os grupos ME e MC. CONCLUSÃO: O LDP mostrou-se reduzido em mulheres com migrânea episódica ou crônica em relação aos controles. Em estudos futuros, esse parâmetro pode ser estudado como marcador da migrânea e indicador de efeito de tratamento.

OBJECTIVE: To estimate the pressure pain threshold (PPT) of the craniocervical muscles in women with episodic migraine (EM) n=15 and chronic migraine (CM) n=14, and in healthy volunteers (C) n=15. METHOD: A blinded examiner obtained the PPT bilaterally, by pressure algometry, for the following muscles: frontalis, temporalis, masseter, trapezius and sternocleidomastoid. ANOVA (p<0.05) was used for statistical purposes. RESULTS: Contrasted to controls, individuals with EM had significantly decreased PPT values for frontal muscle (EM: 2.01±0.67 vs. C: 2.85±0.71), posterior temporalis bilaterally (right and left, respectively) (EM: 2.72±0.89 vs. C: 3.36±0.72 and EM: 2.60±1.00 vs. C: 3.35±0.85), upper trapezius bilaterally (EM: 2.69±1.00 vs. C: 3.49±0.83 and EM: 2.54±0.93 vs. C: 3.32±0.97) and women with CM: on frontal muscle bilaterally (CM: 2.16±0.52 vs. C: 2.79±0.71 and CM: 2.01±0.67 vs. C: 2.85±0.71) and upper trapezius (CM: 2.66±0.84 vs. C: 3.32±0.97), however, it was not verified differences between PPT values between EM and CM groups. CONCLUSION: PPT is decreased in women with migraine relative to controls. Future studies should explore this parameter as a biological marker of the disease and a predictor of treatment.