ABSTRACT The spatial variability of soil attributes in terraced areas is poorly studied in the semi-arid region. Considering that multivariate analysis enhances the diagnosis of spatial variability from geostatistics, soil attributes were studied in different zones between terrace channels in semi-arid region, more precisely in a retention terrace area in Canindé (Ceará, Brazil). Soil samples (n = 100) were collected at depths of 0.0 - 0.1 and 0.1 - 0.2 m for descriptive and geostatistical analysis. For multivariate analysis, samples from three zones relative to the terrace channel (Upper, Middle, and Lower) in the 0.0 - 0.2 m layer were considered, with 30 replicates. There was spatial dependence of soil attributes in the two layers studied. Near the channel, in the respective layers, there was higher clay content (13.7% and 14.7%) and higher degree of flocculation (61.3% and 71.7%) compared to the other zones. Water-dispersible clay was higher in the Upper zone (6.5% and 7.7% in the respective layers), while the Middle zone showed higher potential acidity in the evaluated layers (4.8 and 4.5 cmolc dm-3, respectively) compared to the other zones. In the multivariate analysis, there were highlights for the higher sum of bases in the Upper zone (18.9 ± 0.8 cmolc dm-3), higher sand content in the Middle zone (72.6 ± 0.6%), lower potential acidity (2.1 ± 0.2 cmolc dm-3) and higher phosphorus content (12.8 ± 3.0 mg kg-1) in the Low zone. The zone above the terrace channel loses mainly clay and requires practices to increase water and nutrient retention. semiarid semi arid region geostatistics Ceará, Ceará (Ceará Brazil. Brazil . Brazil) n 100 00 0 0. 01 1 02 2 Upper, (Upper Lower considered 3 replicates 13.7% 137 13 7 (13.7 14.7% 147 14 61.3% 613 61 (61.3 71.7% 717 71 Waterdispersible Water dispersible 6.5% 65 6 5 (6.5 77 7.7 , layers) 4.8 48 4 8 (4. 45 4. dm3, dm3 dm 3, dm-3 respectively 18.9 189 18 9 (18. 08 72.6 726 72 (72. 0.6%, 06 0.6% 0.6%) 2.1 21 (2. 12.8 128 12 (12. 3. kg1 kg kg-1 10 13.7 (13. 14.7 61.3 (61. 71.7 6.5 (6. 7. (4 dm- 18. (18 72. (72 0.6 2. (2 12. (12 kg- 13. (13 14. 61. (61 71. 6. (6 ( (1 (7

Introduction: In general, inflammation stimulates the production and release of neutrophils and, at the same time, decreases the production of lymphocytes. Lymphopenia reflects that cell-mediated immunity is impaired, while neutrophilia represents a response to systemic inflammation in these cancers. Objective: To review the incidence of complications and postoperative survival rates in patients with bone metastases in long bones, correlating them with markers NLR and PLR. Method: Narrative review carried out collecting information published on virtual platforms in Portuguese and English, initially carried out by searching for descriptors related to the topic, which were: “lower extremity, surgery, metastasis, epidemiology, postoperative complications, neutrophils, lymphocytes, platelets”. The extension incorporated AND or OR, by title and/or summary, and full reading of the texts most related to the topic. Result: 21 articles were included. Conclusion: The higher both the NLR and PLR are associated with lower survival in patients with bone metastases when undergoing surgical treatment, especially after 3 months postoperatively. However, there is still no confirmation that they signal any outcome, favorable or not, in relation to postoperative complications.

Introdução : De um modo geral, a inflamação estimula a produção e liberação de neutrófilos e, ao mesmo tempo, diminui a produção de linfócitos. A linfopenia reflete que a imunidade mediada pelas células é prejudicada, enquanto a neutrofilia representa resposta à inflamação sistêmica nesses cânceres. Objetivo : Revisar nos pacientes com metástase óssea em ossos ao longo da incidência de complicações e taxas de sobrevida pós-operatória correlacionando-as com os marcadores NLR e PLR. Método : Revisão narrativa feita colhendo informações publicadas em plataformas virtuais em português e inglês inicialmente realizada por busca dos descritores relacionados ao tema que foram: “extremidade inferior, cirurgia, metástase, epidemiologia, complicações pós-operatórias, neutrófilos, linfócitos, plaquetas” e seus equivalentes em inglês “ extremidade inferior, cirurgia, metástase, epidemiologia, sobrevivência, complicações, neutrófilos, linfócitos, plaquetas sanguíneas ”. A extensão incorporou AND ou OR, pelo título e/ou resumo, e leitura na íntegra dos textos mais relacionados ao tema.  Resultado : Foram incluídos 21 artigos. Conclusão : Quanto maiores, tanto o NLR quanto o PLR estão associados à menor sobrevida em pacientes com MO quando submetidos ao tratamento cirúrgico, especialmente após 3 meses de pós-operatório. Contudo, ainda não há confirmação de que eles sinalizam algum estágio, positivo ou não, em relação às complicações pós-operatórias.

ABSTRACT BACKGROUND: Dynapenia is a risk factor of mortality. Therefore, the development of low-cost and easy-to-apply tools is essential to optimize the health surveillance actions of older people. OBJECTIVES: To compare the time spent on habitual physical activity (HPA) and sedentary behavior (SB) among dynapenic and non-dynapenic older adults and ascertain the predictive ability of these behaviors on outcome. DESIGN AND SETTING: A cross-sectional population epidemiological survey was conducted involving 208 older adults. METHODS: HPA and SB were quantified using the International Physical Activity Questionnaire, and dynapenia was identified by handgrip strength (women: 18.37 kgf; men: 26.75 kgf). RESULTS: The prevalence was 24.50%. In both sexes, dynapenic individuals reported a HPA median time of 70.00 minutes/week (min/wk), while non-dynapenic women and men reported HPA median times of 240.00 and 280.00 min/wk, respectively (P < 0.05). For SB among dynapenic individuals, a median of 388.75 min/day was observed in women and 428.57 min/d in men. In contrast, non-dynapenic women and men had 291.42 and 274.28 min/day in SB (P < 0.05), respectively. The best cutoff HPA to discriminate the outcome was 150.00 min/wk in women (sensitivity: 73.30%; specificity: 60.67%) and 140.00 min/wk in men (sensitivity, 71.43%; specificity, 61.54%). The best cutoff SB was 381.43 min/day in women (sensitivity, 53.30%; specificity, 84.80%) and 351.43 min/day in men (sensitivity, 71.43%; specificity, 73.85%). CONCLUSION: Older individuals with dynapenia spent less time on HPA and more time in SB. Furthermore, HPA was found to be a better discriminator of dynapenic individuals, and SB better discriminated non-dynapenic individuals. BACKGROUND mortality Therefore lowcost low cost easytoapply easy apply people OBJECTIVES (HPA (SB nondynapenic non SETTING crosssectional cross sectional 20 METHODS Questionnaire (women 1837 18 37 18.3 kgf 2675 26 75 26.7 kgf. . kgf) RESULTS 2450 24 50 24.50% sexes 7000 70 00 70.0 minutesweek minutes week minwk , min wk (min/wk) 24000 240 240.0 28000 280 280.0 P 0.05. 005 0.05 0 05 0.05) 38875 388 388.7 minday day 42857 428 57 428.5 mind d contrast 29142 291 42 291.4 27428 274 28 274.2 0.05, 15000 150 150.0 sensitivity (sensitivity 73.30% 7330 73 30 specificity 60.67% 6067 60 67 14000 140 140.0 sensitivity, 71.43% 7143 71 43 61.54%. 6154 61.54% 61 54 61.54%) 38143 381 381.4 53.30% 5330 53 84.80% 8480 84 80 35143 351 351.4 73.85%. 7385 73.85% 85 73.85%) CONCLUSION Furthermore 2 183 1 3 18. 267 7 26. 245 5 24.50 700 70. (min/wk 2400 240. 2800 280. 0.0 3887 38 388. 4285 428. 2914 29 4 291. 2742 27 274. 1500 15 150. 73.30 733 60.67 606 6 1400 14 140. 71.43 714 615 61.54 3814 381. 53.30 533 84.80 848 8 3514 35 351. 738 73.85 24.5 0. 73.3 60.6 71.4 61.5 53.3 84.8 73.8 24. 73. 60. 71. 61. 53. 84.

RESUMO Objetivo: Avaliar as propriedades psicométricas e a confiabilidade da versão brasileira do instrumento Parent Attitudes about Childhood Vaccine (PACV-BR). Métodos: A amostra incluiu 110 pais de crianças de até dois anos atendidas em Unidades Básicas de Saúde da Família. A consistência interna e a validade fatorial do instrumento foram avaliadas, respectivamente, pelo alfa de Cronbach e pela análise fatorial exploratória (EFA). A confiabilidade teste-reteste foi avaliada pelo coeficiente de correlação intraclasse (ICC). Resultados: Os resultados da AFE indicaram adequação estrutural do PACV-BR (15 itens e dois fatores). A confiabilidade indicou valores de alfa de Cronbach entre 0,715 e 0,854 para os itens, de 0,918 para o instrumento como um todo, de 0,877 para o fator 1 e de 0,825 para o fator 2, além de ICC de 0,984. Conclusões: O PACV-BR apresentou evidências de validade de construto e confiabilidade. Objetivo PACVBR. PACVBR PACV BR . (PACV-BR) Métodos 11 Família avaliadas respectivamente EFA. EFA (EFA) testereteste teste reteste ICC. (ICC) Resultados 15 (1 fatores. fatores fatores) 0715 0 715 0,71 0854 854 0,85 0918 918 0,91 todo 0877 877 0,87 0825 825 0,82 2 0984 984 0,984 Conclusões (PACV-BR (EFA (ICC ( 071 71 0,7 085 85 0,8 091 91 0,9 087 87 082 82 098 98 0,98 07 7 0, 08 8 09 9

ABSTRACT Objective: To evaluate the psychometric properties and reliability of the Brazilian version of the tool Parent Attitudes about Childhood Vaccine (PACV-BR). Methods: The sample included 110 parents of children up to two years old served by Family Health Basic Units. The tool's internal consistency and factor validity were respectively assessed by Cronbach's alpha and exploratory factor analysis (EFA). The test-retest reliability was assessed by the intraclass correlation coefficient (ICC). Results: The EFA results indicated a proper structural adequacy of the PACV-BR (15 items and two factors). The reliability generated Cronbach's alpha values between 0.715 and 0.854 for the items, of 0.918 for the tool as a whole, of 0.877 for factor 1 and of 0.825 for factor 2, in addition to an ICC of 0.984. Conclusions: The PACV-BR showed evidence of construct validity and reliability. Objective PACVBR. PACVBR PACV BR . (PACV-BR) Methods 11 Units tools s Cronbachs Cronbach EFA. (EFA) testretest test retest ICC. (ICC) Results 15 (1 factors. factors factors) 0715 0 715 0.71 0854 854 0.85 0918 918 0.91 whole 0877 877 0.87 0825 825 0.82 2 0984 984 0.984 Conclusions (PACV-BR (EFA (ICC ( 071 71 0.7 085 85 0.8 091 91 0.9 087 87 082 82 098 98 0.98 07 7 0. 08 8 09 9

ABSTRACT Objective: To evaluate the prevalence of sharps accidents among dental students in southwest Goiás state, Brazil, and further survey their knowledge of biosafety and post-injury management. Material and Methods: A cross-sectional analytical observational study was carried out in 2018 following the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) guidelines. The study population included dental students in the 4th and 10th course semester. A pre-formulated self-administered questionnaire containing 14 objective questions was used for data collection. Mean and standard deviation values were calculated. Results: A total of 308 responses were obtained. Overall, 15.9% of the respondents reported having previously experienced accidents with sharps. Most dental students who claimed to know the biological risks to which they are exposed were in the 5th and 8th course semesters, and 67.2% of them reported knowing how to proceed in the event of a sharp accident. Conclusion: A low prevalence of sharps accidents has been reported, and dental students are considered to have a good knowledge of biosafety. Objective state Brazil postinjury post injury management Methods crosssectional cross sectional 201 STROBE (STROBE guidelines th semester preformulated pre formulated selfadministered self administered 1 collection calculated Results 30 obtained Overall 159 15 9 15.9 semesters 672 67 2 67.2 accident Conclusion 20 3 15. 6 67.

RESUMO O câncer de pulmão (CP) é uma das neoplasias mais comuns e letais no Brasil, e apenas 15% dos pacientes são diagnosticados nos estágios iniciais. O tabagismo persiste como o responsável por mais de 85% de todos os casos. O rastreamento do CP (RCP) por meio da TC de baixa dosagem de radiação (TCBD) reduz a mortalidade do CP em 20%, e, quando combinado com a cessação do tabagismo, essa redução chega a 38%. Na última década, diversos países adotaram o RCP como recomendação de saúde populacional. No Brasil, embora ainda incipiente, a discussão sobre o tema é cada vez mais ampla e necessária. Com o intuito de aumentar o conhecimento e estimular o debate sobre o RCP, a Sociedade Brasileira de Cirurgia Torácica, a Sociedade Brasileira de Pneumologia e Tisiologia e o Colégio Brasileiro de Radiologia e Diagnóstico por Imagem constituíram um painel de especialistas para elaborar as recomendações para o RCP. As recomendações aqui apresentadas foram baseadas em revisão narrativa da literatura, com ênfase em grandes estudos populacionais, em revisões sistemáticas e em recomendações de diretrizes internacionais, sendo construídas após ampla discussão pelo grupo de especialistas. Os temas revisados foram os seguintes: porque rastrear, considerações gerais sobre tabagismo, epidemiologia do CP, critérios de elegibilidade, achados incidentais, lesões granulomatosas, modelos probabilísticos, requisitos mínimos da TCBD, aquisições volumétricas, riscos do rastreamento, estrutura mínima e papel da equipe multidisciplinar, conduta segundo o Lung CT Screening Reporting and Data System (Lung-RADS), custos vs. benefícios e perspectivas do rastreamento. (CP Brasil 15 iniciais 85 casos (RCP TCBD (TCBD 20 20% 38 38% década populacional incipiente necessária Torácica literatura populacionais internacionais seguintes rastrear elegibilidade incidentais granulomatosas probabilísticos volumétricas multidisciplinar LungRADS, LungRADS RADS , (Lung-RADS) vs 1 8 2 3 (Lung-RADS

ABSTRACT Although lung cancer (LC) is one of the most common and lethal tumors, only 15% of patients are diagnosed at an early stage. Smoking is still responsible for more than 85% of cases. Lung cancer screening (LCS) with low-dose CT (LDCT) reduces LC-related mortality by 20%, and that reduction reaches 38% when LCS by LDCT is combined with smoking cessation. In the last decade, a number of countries have adopted population-based LCS as a public health recommendation. Albeit still incipient, discussion on this topic in Brazil is becoming increasingly broad and necessary. With the aim of increasing knowledge and stimulating debate on LCS, the Brazilian Society of Thoracic Surgery, the Brazilian Thoracic Association, and the Brazilian College of Radiology and Diagnostic Imaging convened a panel of experts to prepare recommendations for LCS in Brazil. The recommendations presented here were based on a narrative review of the literature, with an emphasis on large population-based studies, systematic reviews, and the recommendations of international guidelines, and were developed after extensive discussion by the panel of experts. The following topics were reviewed: reasons for screening; general considerations about smoking; epidemiology of LC; eligibility criteria; incidental findings; granulomatous lesions; probabilistic models; minimum requirements for LDCT; volumetric acquisition; risks of screening; minimum structure and role of the multidisciplinary team; practice according to the Lung CT Screening Reporting and Data System; costs versus benefits of screening; and future perspectives for LCS. LC (LC tumors 15 stage 85 cases (LCS lowdose low dose (LDCT LCrelated related 20 20% 38 cessation decade populationbased population recommendation incipient necessary Surgery Association literature studies reviews guidelines reviewed criteria findings lesions models acquisition team System 1 8 2 3

ABSTRACT The article examines the use of images in journalism, their contribution to the social construction of reality, and the establishment of an aesthetic of truth throughout the technical evolution of media. The research seeks to understand the effects of digital platforms and social networks on the production and distribution of information. A central hypothesis is that the new information system, stripped of traditional journalistic codes and other institutional filters, creates a space where facts, reality, and fantasy converge. This facilitates the spread of fake news and misinformation, weakening the image's capacity to represent a world beyond itself. The research adopts a qualitative analysis of digital platform content based on a critical reading of selected images and a review of both classic and contemporary literature.

RESUMO O artigo examina o uso de imagens no jornalismo, a sua contribuição na construção social da realidade e o estabelecimento de uma estética da verdade ao longo da evolução técnica dos meios de comunicação. A pesquisa pretende compreender os efeitos das plataformas digitais e das redes sociais na produção e distribuição de informações. Uma hipótese central é que o novo sistema de informação, despojado dos códigos tradicionais do jornalismo e de outros filtros institucionais, cria um espaço onde convergem fatos, realidade e fantasia. Isso facilita a disseminação de fake news e desinformação, enfraquecendo a capacidade da imagem de representar um mundo fora de si mesma. A pesquisa adota uma análise qualitativa do conteúdo das plataformas digitais, a partir da leitura crítica de imagens selecionadas e de uma revisão da literatura, tanto clássica quanto contemporânea.

RESUMEN El artículo examina el uso de imágenes en el periodismo, su contribución a la construcción social de la realidad y el establecimiento de una estética de la verdad en el marco de la evolución técnica de los medios de comunicación. La investigación busca comprender los efectos de las plataformas digitales y las redes sociales en la producción y la distribución de la información. Una hipótesis central es que el nuevo sistema de información, apartado de los códigos tradicionales del periodismo y de otros filtros institucionales, crea un espacio donde convergen hechos, realidad y fantasía. Esto facilita la difusión de fake news y desinformación, debilitando la capacidad de la imagen para representar un mundo fuera de sí misma. La investigación adopta un análisis cualitativo del contenido de las plataformas digitales, a partir de la lectura crítica de imágenes seleccionadas y de una revisión de la literatura, tanto clásica como contemporánea.

Resumo Uma nova espécie de Moenkhausia do rio Culuene, bacia do rio Xingu é descrita aqui através da utilização de dados morfológicos e genéticos. Esta nova espécie difere de todas as suas congêneres por possuir a seguinte combinação de caracteres: a presença da porção posterior do corpo e a base das nadadeiras anal, adiposa e pélvicas avermelhadas em espécimes vivos; uma faixa meio-lateral escura que se estende da margem posterior do opérculo até os raios medianos da nadadeira caudal, tornando-se larga a partir da origem da nadadeira dorsal; ausência de uma mancha na região umeral; ausência de mancha nos lobos da nadadeira caudal; por ter uma concentração de pigmentos escuros na margem anterior dos raios da nadadeira caudal; e presença de 2–3 dentes no maxilar. Uma breve discussão sobre suas prováveis relações com as demais congêneres é apresentada. Culuene genéticos caracteres anal vivos meiolateral meio lateral caudal tornandose tornando dorsal umeral 23 2 3 2– maxilar apresentada

Abstract A new species of Moenkhausia from the rio Culuene, rio Xingu basin, in Mato Grosso State is described here through genetic and morphological data. This new species differs from all congeners by the following combination of characters: the presence of reddish color on the posterior portion of the body, as well as on the base of anal, adipose, and pelvic fins in live specimens; a conspicuous midlateral dark stripe, which extends from posterior margin of opercle to the middle of caudal-fin rays, becoming wider and more conspicuous from the vertical through the dorsal-fin origin; absence of humeral blotch; absence of blotches on caudal-fin lobes; by having the concentration of dark pigments on the anterior margin of the caudal-fin rays; and presence of 2–3 maxillary teeth. A brief discussion about its putative relationships with other congeners is presented. Culuene basin data characters body anal adipose specimens stripe caudalfin caudal fin rays dorsalfin dorsal origin blotch lobes 23 2 3 2– teeth presented

Resumo Objetivou-se identificar características indicadoras de precocidade sexual de fácil mensuração e que podem ser registradas em menor idade (idade à primeira concepção - IPC), além de estimar as correlações genéticas dessa característica com aquelas de crescimento e carcaça em bovinos Nelore. A IPC foi considerada a idade em que a fêmea apresentou o primeiro diagnóstico positivo de prenhez. A estimativa dos componentes de (co)variância e dos parâmetros genéticos foi realizada usando modelo animal linear em análises bicaracterísticas. As estimativas de herdabilidade foram moderadas, indicando viabilidade de seleção genética para características de crescimento, carcaça e precocidade sexual. As correlações genéticas obtidas entre o IPC e a idade ao primeiro parto (IPP) foram altas (0,88), indicando a viabilidade do uso de IPC como critério de seleção para parto em idade precoce de novilhas. As estimativas de correlações genéticas entre IPC e IPP com peso aos 120, 210, 365 e 450 dias de idade e características de carcaça foram moderadas e negativas (-0,33 a -0,62). Assim, a seleção genética para animais com IPC e IPP precoces aumentaria o rendimento de carcaça, a deposição de gordura e o peso corporal, embora não afete o peso ao nascer e o ganho de peso diário. Os resultados deste estudo encorajam o uso de IPC em bovinos Nelore, uma vez que esta característica apresentou variabilidade genética em bovinos Nelore, podendo ser utilizada como critério de seleção para melhorar a precocidade sexual. Quando o objetivo de seleção genética é aumentar a precocidade sexual das novilhas, indica-se o uso de IPC como critério, pois a mensuração desta característica ocorre em idade menor IPP. Objetivouse Objetivou se IPC, , IPC) Nelore prenhez covariância co variância bicaracterísticas (IPP 0,88, 088 0,88 0 88 (0,88) novilhas 120 210 36 45 0,33 033 33 (-0,3 0,62. 062 0,62 . 62 -0,62) Assim corporal diário indicase indica 08 0,8 8 (0,88 12 21 3 4 0,3 03 (-0, 06 0,6 6 -0,62 0, (0,8 1 2 (-0 -0,6 (0, (- -0, (0 ( -0

Abstract The aim was to identify predictive traits of relatively easy measurement and which can be recorded early in life (age at first conception - AFCo), besides estimating its genetic correlations with growth and carcass traits in Nellore cattle. Age at first conception was considered the age at which the female had the first positive diagnosis for pregnancy. The estimation of (co)variance components and genetic parameters was performed using a linear animal model in two-trait analysis. The estimates of heritability were moderate, enabling genetic selection for growth-, carcass-, and sexual precocityrelated traits. The genetic correlation obtained between AFCo and age at first calving (AFCa) was high (0.88), indicating the feasibility of using AFCo as a selection criterion for early calving heifers. Genetic correlation estimates between AFCo and AFCa with weight at 120, 210, 365, and 450 days of age and carcass traits were moderate and negative (-0.33 to -0.62). Thus, genetic selection for animals with early AFCo and AFCa would enhance carcass yield, fat deposition, and growth performance, despite not affecting birth weight or daily weight gain. The results of this study encourage the use of AFCo in Nellore cattle since this trait displayed enough genetic variability in Nellore cattle, and can be used as selection criteria to improve sexual precocity. When the objective of genetic selection is to increase heifer sexual precocity, we could use the first trait as a criterion, as the measurement of this trait occurs at a lower AFCa. AFCo, , AFCo) pregnancy covariance co variance twotrait two analysis growth, growth- carcass, carcass- (AFCa 0.88, 088 0.88 0 88 (0.88) heifers 120 210 365 45 0.33 033 33 (-0.3 0.62. 062 0.62 . 62 -0.62) Thus yield deposition performance gain precocity 08 0.8 8 (0.88 12 21 36 4 0.3 03 3 (-0. 06 0.6 6 -0.62 0. (0.8 1 2 (-0 -0.6 (0. (- -0. (0 ( -0

Abstract Background Hand osteoarthritis (HOA) is a highly prevalent disease that may be impacted by social inequalities. Few studies in HOA are from underdeveloped regions. We intend to contribute to fill this gap presenting clinical characteristics of our low-income HOA cohort (LIHOA). Methods Data from 119 patients with a HOA diagnosis fulfilling ACR criteria seen between August 2019 and May 2023 in Fortaleza/Brazil. Evaluations included pain (VAS, visual analogue scale), X-ray (KL, Kellgren-Lawrence), grip and pinch strength (KgF), Cochin hand functional scale (CHFS), FIHOA, and SF-12 scores. Social data included monthly (<1, 1≥/<3, ≥3 MW) minimum wage earnings, occupation, and literacy [</≥ 9 school-years (SY)]. Results 107 out of the 119 patients were included. Mean age was 61.9 (±10.3) years with 94 (92%) women. Systemic arterial hypertension (48%), metabolic syndrome (42.8%), dyslipidemia (28.4%), and obesity (25%) were the most common comorbidities. Mean disease duration was 7.5 ± 7.1 years. Median VAS values at rest and activity were 3 (3–5) and 8 (5–9), respectively (p < 0.001). Fifty-seven (56.4%) patients had ≥4 symptomatic joints with a median of 4 (2–8) painful joints at activity. The 2nd distal interphalangeal (IF), joint was the most symptomatic (21; 23.3%) and most had >4 IF nodes. OA in other joints: 37 (36.2%) spine, 28 (29.4%) knee, 21 (20.5%) bunions. Functional impairment was mild [8 (5–14) median FIHOA]. Median serum CRP was 0.2 mg/dL (0.1–0.4) with 14 (20%) patients above reference value. Mean total KL score was 27.6 ± 13.6 with 21 (23%), 38 (41.7%), and 33 (36.2%) KL2, KL3, and KL4, respectively; 51 (54.8%) and 42 (45.2%) patients declared </≥3 MW earnings, respectively. Most declared >9SY including 37.2% with a university degree. Individuals earning <3 MW had lower pinch (p < 0.004) and grip strength (p < 0.01), and higher FIHOA scores (p < 0.007), as compared to ≥3 MW earning group. Literacy or occupation did not impact outcome. SYSADOA were used by 13 (12.7%), 6 used oral and 3 topical anti-inflammatory drugs and 2 used 5 mg/d prednisone. Conclusion Clinical characteristics in our LIHOA cohort mirror those reported in affluent regions. Socioeconomic disparities influenced functional outcome in LIHOA cohort. (HOA inequalities regions lowincome low income LIHOA. . (LIHOA) 11 201 202 FortalezaBrazil Fortaleza Brazil Fortaleza/Brazil VAS, (VAS scale, , scale) Xray X ray KL, (KL KellgrenLawrence, KellgrenLawrence Kellgren Lawrence Kellgren-Lawrence) KgF, KgF (KgF) CHFS, CHFS (CHFS) SF12 SF 12 SF-1 <1, 1 (<1 1≥/<3 ≥ earnings </≥ [</ schoolyears school SY. SY (SY)] 10 619 61 61. ±10.3 103 (±10.3 92% 92 (92% women 48%, 48 48% (48%) 42.8%, 428 42.8% (42.8%) 28.4%, 284 28.4% (28.4%) 25% 25 (25% comorbidities 75 7 7. 71 3–5 35 (3–5 5–9, 59 5–9 (5–9) p 0.001. 0001 0.001 0 001 0.001) Fiftyseven Fifty seven 56.4% 564 56 (56.4% 2–8 (2–8 nd IF, (IF) (21 23.3% 233 23 > nodes 36.2% 362 36 (36.2% spine 29.4% 294 29 (29.4% knee 20.5% 205 20 (20.5% bunions [ 5–14 514 (5–14 FIHOA. FIHOA] 02 0. mgdL mg dL 0.1–0.4 0104 (0.1–0.4 20% (20% value 276 27 27. 136 13. 23%, 23% (23%) 41.7%, 417 41.7% 41 (41.7%) KL2 KL3 KL4 54.8% 548 54 (54.8% 45.2% 452 45 (45.2% 9SY 372 37.2 degree 0.004 0004 004 0.01, 0.01 01 0.01) 0.007, 0007 0.007 007 0.007) group 12.7%, 127 12.7% (12.7%) antiinflammatory anti inflammatory mgd d prednisone (LIHOA Kellgren-Lawrence (KgF (CHFS SF1 SF- <1 (< 1≥/< </ [< (SY) ±10. (±10. (92 (48% 42.8 (42.8% 28.4 (28.4% (25 3– (3– 5– (5–9 000 0.00 00 56.4 (56.4 2– (2– (IF (2 23.3 36.2 (36.2 29.4 (29.4 20.5 (20.5 5–1 (5–1 0.1–0. 010 (0.1–0. (20 (23% 41.7 (41.7% 54.8 (54.8 45.2 (45.2 37. 0.0 12.7 (12.7% ( 1≥/ (SY ±10 (±10 (9 (48 42. (42.8 28. (28.4 (3 (5– 56. (56. 23. 36. (36. 29. (29. 20. (20. 0.1–0 (0.1–0 (23 41. (41.7 54. (54. 45. (45. 12. (12.7 1≥ ±1 (±1 (4 (42. (28. (5 (56 (36 (29 0.1– (0.1– (41. (54 (45 (12. (± (42 (28 0.1 (0.1 (41 (12 (0. (1 (0

ABSTRACT CP football is played by male athletes with cerebral palsy, with rules similar to soccer, with some adaptations, but with the same demands for results and motor performance. Therefore, the objective of this study was to identify and analyze the anthropometric profile, body composition, somatotype, and motor performance of CP Football athletes, according to the impairment topography, sport class and game position. Thirty-seven athletes from the Brazilian CP football team participated in the study, who had body mass, height, circumference, bone diameters, skinfold thickness, and agility, speed and aerobic capacity VO2max tests. The motor performance of CP football athletes, in speed and aerobic capacity tests were significantly different (p<0.05) according to the impairment topography. Significant correlations were found between the impairment topography and sport classes for the variable’s agility (r= 0.39 and r= -0.40), 30m speed (r= 0.50 and r= -0.48) and the aerobic capacity VO2 max (r= -0.39 and r= 0.62). This study presents indications that the anthropometric, body composition and somatotype variables do not differ according to the impairment topography, functional class and game position in CP football athletes. Such findings can be guiding for the teams of the modality, as they differ from the conventional sport. palsy soccer adaptations Therefore profile Thirtyseven Thirty seven mass height circumference diameters thickness VOmax VO p<0.05 p005 p 0 05 (p<0.05 variable s r (r 039 39 0.3 0.40, 040 0.40 , 40 -0.40) m 050 50 0.5 0.48 048 48 -0.48 -0.3 0.62. 062 0.62 . 62 0.62) modality p<0.0 p00 (p<0.0 03 3 0. 04 0.4 4 -0.40 5 -0.4 -0. 06 0.6 6 p<0. p0 (p<0. -0 p<0 (p<0 - p< (p< (p

RESUMO Introdução: a pandemia COVID-19 levou a um importante declínio mundial no volume cirúrgico devido ao adiamento de procedimentos eletivos. Este estudo avaliou o impacto da pandemia COVID-19 nos volumes e nos resultados da cirurgia abdominal em pacientes criticos. Métodos: pacientes internados para cuidados pósoperatórios foram avaliados retrospectivamente. Dados relativos aos desfechos perioperatórios foram comparados em dois períodos: janeiro-2017 a dezembro-2019 e janeiro-2020 a dezembro-2022, respectivamente, antes (período I) e depois (período II) da pandemia COVID-19. Resultados: foram investigados 1.402 pacientes (897 mulheres, idade 62+17 anos). A maioria dos pacientes foi submetida a cirurgia colorretal (n=393) e pancreatobiliar (n=240), sendo 52% dos procedimentos eletivos. O volume cirúrgico foi significativamente menor no período II (n=514) quando comparado ao período I (n=888). Não foi observada recuperação no número de procedimentos cirúrgicos em 2022 (n=135) quando comparado a 2021 (n=211) e 2020 (n=168). Indivíduos submetidos à cirurgia abdominal no período II apresentaram maior índice de comorbidade de Charlson (4,85+3,0 vs. 4,35+2,8, p=0,002), mais procedimentos emergenciais/urgentes (51% vs. 45%, p =0,03) e mais feridas potencialmente contaminadas (73,5% vs. 66,8%, p=0,02). Observou-se diminuição significativa no volume de cirurgia colorretal (24% vs, 31%, p<0,0001) após o início da pandemia de COVID-19, com 125 (8,9%) óbitos, nenhuma morte por COVID-19. A mortalidade foi maior no período II quando comparada ao período I (11% vs. 8%, p=0,08). Conclusões: a pandemia de COVID-19 foi associada à diminuição do volume cirúrgico de pacientes de alto risco sem recuperação aparente nos últimos anos. Nenhuma influência da COVID-19 foi observada na mortalidade pósoperatória. Introdução COVID19 COVID 19 COVID-1 eletivos criticos Métodos retrospectivamente períodos janeiro2017 janeiro 2017 janeiro-201 dezembro2019 dezembro 2019 dezembro-201 janeiro2020 janeiro-202 dezembro2022, dezembro2022 2022, dezembro-2022 respectivamente COVID19. 19. Resultados 1402 1 402 1.40 897 (89 mulheres 6217 62 17 62+1 anos . anos) n=393 n393 n 393 (n=393 n=240, n240 n=240 , 240 (n=240) 52 n=514 n514 514 (n=514 n=888. n888 n=888 888 (n=888) 202 n=135 n135 135 (n=135 n=211 n211 211 (n=211 n=168. n168 n=168 168 (n=168) 4,85+3,0 48530 4 85 3 0 (4,85+3, vs 43528 35 2 8 4,35+2,8 p=0,002, p0002 p=0,002 002 p=0,002) emergenciaisurgentes emergenciais urgentes 51% 51 (51 45 45% =0,03 003 03 73,5% 735 73 5 (73,5 668 66 66,8% p=0,02. p002 p=0,02 02 p=0,02) Observouse Observou se 24% 24 (24 31 31% p<0,0001 p00001 0001 COVID19, 19, 12 8,9% 89 9 (8,9% óbitos 11% 11 (11 8% p=0,08. p008 p=0,08 08 p=0,08) Conclusões pósoperatória COVID1 COVID- janeiro201 201 janeiro-20 dezembro201 dezembro-20 janeiro202 dezembro202 dezembro-202 140 40 1.4 (8 621 6 62+ n=39 n39 39 (n=39 n24 n=24 (n=240 n=51 n51 (n=51 n88 n=88 88 (n=888 20 n=13 n13 13 (n=13 n=21 n21 21 (n=21 n16 n=16 16 (n=168 4,85+3, 4853 (4,85+3 4352 4,35+2, p000 p=0,00 00 (5 =0,0 73,5 7 (73, 66,8 p00 p=0,0 (2 p<0,000 p0000 000 8,9 (8,9 (1 janeiro20 janeiro-2 dezembro20 dezembro-2 14 1. ( n=3 n3 (n=3 n2 n=2 (n=24 n=5 n5 (n=5 n8 n=8 (n=88 n=1 n1 (n=1 (n=2 (n=16 4,85+3 485 (4,85+ 435 4,35+2 =0, 73, (73 66, p0 p=0, p<0,00 8, (8, janeiro2 janeiro- dezembro2 dezembro- n= (n= (n=8 4,85+ 48 (4,85 43 4,35+ =0 (7 p=0 p<0,0 (n 4,85 (4,8 4,35 = p= p<0, 4,8 (4, 4,3 p<0 4, (4 p<

ABSTRACT Backgrounds: COVID-19 pandemic led to a sharp decline in surgical volume worldwide due to the postponement of elective procedures. This study evaluated the impact of COVID-19 pandemic in surgical volumes and outcomes of abdominal surgery in high-risk patients requiring intensive care unit admission. Methods: patients admitted for postoperative care were retrospectively evaluated. Data concerning perioperative variables and outcomes were compared in two different periods: January 2017-December 2019 and January 2020-December 2022, respectively, before (period I) and after (period II) the onset of COVID-19 pandemic. Results: 1.402 patients (897 women, mean age 62+17 years) were investigated. Most of the patients underwent colorectal (n=393) and pancreato-biliary (n=240) surgery, 52% of elective procedures. Surgical volume was significantly lower in period II (n=514) when compared to period I (n= 888). No recovery was observed in the number of surgical procedures in 2022 (n=135) when compared to 2021(n=211) and 2020 (n=168). Subjects who underwent abdominal surgery in period II had higher Charlson comorbidity index (4,85+3,0 vs. 4,35+2,8, p=0,002), more emergent/urgent procedures (51% vs. 45%, p=0,03) and more clean-contaminated wounds (73,5% vs. 66,8%, p=0,02). A significant decrease in the volume of colorectal surgery was also observed (24% vs, 31%, p<0,0001) after the onset of COVID-19 pandemic, 125 (8,9%) died, no deaths due to COVID-19 infection. Mortality was higher in period II when compared to period I (11% vs. 8%, p=0,08). Conclusions: COVID-19 pandemic was associated with a decrease in surgical volume of high-risk patients without apparent recovery in recent years. No influence of COVID-19 was noted in postoperative mortality. Backgrounds COVID19 COVID 19 COVID-1 highrisk high risk admission Methods periods 2017December December 2017 201 2020December respectively Results 1402 1 402 1.40 897 (89 women 6217 62 17 62+1 years investigated n=393 n393 n 393 (n=393 pancreatobiliary pancreato biliary n=240 n240 240 (n=240 52 n=514 n514 514 (n=514 n= (n 888. 888 . 888) 202 n=135 n135 135 (n=135 2021n=211 2021n211 2021 n=211 211 2021(n=211 n=168. n168 n=168 168 (n=168) 4,85+3,0 48530 4 85 3 0 (4,85+3, vs 43528 35 2 8 4,35+2,8 p=0,002, p0002 p p=0,002 , 002 p=0,002) emergenturgent emergent urgent 51% 51 (51 45 45% p=0,03 p003 03 cleancontaminated clean contaminated 73,5% 735 73 5 (73,5 668 66 66,8% p=0,02. p002 p=0,02 02 p=0,02) 24% 24 (24 31 31% p<0,0001 p00001 0001 12 8,9% 89 9 (8,9% died infection 11% 11 (11 8% p=0,08. p008 p=0,08 08 p=0,08) Conclusions mortality COVID1 COVID- 20 140 40 1.4 (8 621 6 62+ n=39 n39 39 (n=39 n=24 n24 (n=24 n=51 n51 (n=51 88 n=13 n13 13 (n=13 2021n 2021n=21 2021n21 n211 n=21 21 2021(n=21 n16 n=16 16 (n=168 4,85+3, 4853 (4,85+3 4352 4,35+2, p000 p=0,00 00 (5 p=0,0 p00 73,5 7 (73, 66,8 (2 p<0,000 p0000 000 8,9 (8,9 (1 14 1. ( n=3 n3 (n=3 n=2 n2 (n=2 n=5 n5 (n=5 n=1 n1 (n=1 2021n=2 2021n2 n21 2021(n=2 (n=16 4,85+3 485 (4,85+ 435 4,35+2 p=0, p0 73, (73 66, p<0,00 8, (8, 2021n= 2021(n= 4,85+ 48 (4,85 43 4,35+ p=0 (7 p<0,0 2021(n 4,85 (4,8 4,35 p= p<0, 4,8 (4, 4,3 p<0 4, (4 p<

Abstract Peri-implant diseases, including peri-implant mucositis (PIM) and peri-implantitis, are a chronic inflammatory disorder triggered by bacterial biofilm in susceptible hosts. Potential risk factors for peri-implant diseases include smoking, dental plaque accumulation, poor oral hygiene, genetics, and absence of peri-implant keratinized mucosa. This cohort study aimed to evaluate the influence of patient-, implant-, and prosthetic-related factors on PIM and peri-implant bone loss (PBL) around dental implants after 1 year of loading. A total of 54 subjects (22 males and 32 females) were included in the study. Peri-implant clinical parameters were assessed and standardized periapical radiographs of each dental implant were obtained 15 days after the definitive prosthesis installation (baseline) and at 3, 6, and 12 months of follow-up. A total of 173 implants were evaluated. PIM affected 44.8% of the implants and no significant association was found between the investigated parameters and PIM incidence, except for type of implant connection. A significantly higher incidence of PIM (80.0%) was observed for implants with internal hexagon connection type after 1 year of follow-up (p = 0.015). Moreover, a mean PBL of 0.35 ± 1.89 mm was observed and no dental implant was affected by peri-implantitis after 1 year of function. No specific influence of patient, implant, or prosthetic factors on PBL was observed. No association was found between the occurrence of PIM/PBL and the patient-, implant-, and prosthetic-related factors investigated in this cohort study, except for the type of dental-implant connection. Periimplant Peri periimplant peri (PIM periimplantitis, periimplantitis implantitis, implantitis hosts smoking accumulation hygiene genetics mucosa patient , patient- implant- prostheticrelated related (PBL loading 5 22 (2 3 females baseline (baseline 6 followup. followup follow up. up 17 evaluated 448 44 8 44.8 80.0% 800 80 0 (80.0% p 0.015. 0015 0.015 . 015 0.015) Moreover 035 35 0.3 189 89 1.8 function PIMPBL dentalimplant 2 ( 4 44. 80.0 (80.0 001 0.01 01 03 0. 18 1. 80. (80. 00 0.0 (80 (8

RESUMO Objetivo: Este estudo objetiva revisar a literatura e compartilhar experiências clínicas, enfatizando sua relevância diagnóstica em crianças com menos de 5 anos. Método: Estudamos 169 casos de Doença de Legg-Calvé-Perthes (DLCP) em pacientes desta faixa etária. Analisamos prontuários e imagens, observando variáveis como idade, gênero, queixas, tratamento e resultados. Resultados: Estudamos 20 pacientes com displasia de Meyer, que representavam 1,4% dos casos de DLCP em crianças. A maioria eram meninos (85%) com início dos sintomas aos 38 meses. Claudicação (25%) e dor leve (40%) foram as principais queixas. Achados radiográficos mostraram núcleo menor, granular ou assimétrico. O acompanhamento médio foi de 6,4 anos, com tratamento intervencionista em cinco dos casos. A maioria apresentou reossificação completa e centralização da cabeça femoral. Conclusão: A Displasia de Meyer é uma condição rara que afeta o quadril em crianças menores de 5 anos, predominantemente em meninos. Geralmente, não requer tratamento intensivo; os acompanhamentos clínico e radiológico são suficientes. Contudo, é importante estar ciente de possíveis evoluções desfavoráveis, requerendo tratamento mais agressivo para evitar sequelas. Nível de Evidência III, Estudo restrospectivo comparativo. Objetivo clínicas anos Método 16 LeggCalvéPerthes Legg Calvé Perthes (DLCP etária imagens idade gênero queixas resultados Resultados 2 14 1 4 1,4 85% 85 (85% 3 meses 25% 25 (25% 40% 40 (40% menor assimétrico 64 6 6, femoral Conclusão Geralmente intensivo suficientes Contudo desfavoráveis sequelas III comparativo 1, 8 (85 (25 (40 (8 (2 (4 (

ABSTRACT Objective: This study reviews the literature and shares clinical experiences, emphasizing its diagnostic relevance in children under 5 years of age. Method: We examined 169 cases of Legg-Calvé-Perthes disease (LCPD) in patients in this age group. We analyzed medical records and images, observing variables such as age, gender, complaints, treatment, and outcomes. Results: We studied 20 patients with Meyer’s dysplasia, representing 1.4% of LCPD cases in children. The majority were boys (85%) with symptom onset at 38 months. Claudication (25%) and mild pain (40%) were the main complaints. Radiographic findings showed a smaller, granular, or asymmetric nucleus. The average follow-up was 6.4 years, with interventional treatment in 5 cases. Most showed complete reossification and centralization of the femoral head. Conclusion: Meyer’s dysplasia is a rare condition that affects the hip in children under 5 years of age, predominantly in boys. It usually does not require intensive treatment; clinical and radiological follow-up is sufficient. However, it is important to be aware of possible unfavorable progressions, requiring more aggressive treatment to prevent complications. Level of evidence III, Retrospective comparative study. Objective experiences Method 16 LeggCalvéPerthes Legg Calvé Perthes (LCPD group images gender complaints outcomes Results 2 Meyers Meyer s 14 1 4 1.4 85% 85 (85% 3 months 25% 25 (25% 40% 40 (40% smaller granular nucleus followup follow up 64 6 6. head Conclusion sufficient However progressions complications III 1. 8 (85 (25 (40 (8 (2 (4 (