Abstract Background In most cases, atherosclerotic cardiovascular disease (ACVD) is preventable through primary prevention and control of traditional risk factors, such as smoking cessation, regular physical activity, and adherence to healthy dietary patterns. The assessment of diet quality of ACVD patients would be important for a dietary intervention. Objectives This study aimed to evaluate diet quality of ACVD patients and its association with clinical conditions. Methods This cross-sectional study was nested within a randomized clinical trial entitled “Programa Alimentar Cardioprotetor Brasileiro.” Baseline data of 80 patients from Pelotas, Brazil, were obtained. Food consumption was assessed using 24-h food recall and the Revised Diet Quality Index (IQD-R). Data on smoking status and comorbidities were reported by the patients during medical history taking. To analyze the associations between IQD-R and clinical variables, unpaired Student’s t-test or the analysis of variance was performed. The significance level was 5%. Results Most of the sample consisted of men (66.5%), elderly individuals (52.50%), patients with hypertension (78.75%), dyslipidemia (58.75%), and overweight (73.75%). The average IQD-R score was 56.7 ± 12.6 points. Better quality of diet was observed for patients with diabetes compared to those without diabetes (61.1 ± 11.8 versus 54.0 ± 12.6 points; p=0.014). Conclusion There is a need to improve diet quality of ACVD patients. Patients ACVD and diabetes had better diet quality compared to those without diabetes. cases (ACVD factors cessation activity patterns intervention conditions crosssectional cross sectional Programa Brasileiro. Brasileiro 8 Pelotas Brazil obtained 24h h 24 IQDR. IQDR IQD R . (IQD-R) taking variables Students Student s ttest t test performed 5 5% 66.5%, 665 66.5% , 66 (66.5%) 52.50%, 5250 52.50% 52 50 (52.50%) 78.75%, 7875 78.75% 78 75 (78.75%) 58.75%, 5875 58.75% 58 (58.75%) 73.75%. 7375 73.75% 73 (73.75%) 567 56 7 56. 126 12 6 12. points 61.1 611 61 1 (61. 118 11 11. 540 54 0 54. p=0.014. p0014 p p=0.014 014 p=0.014) 2 (IQD-R 66.5 (66.5% 525 52.50 (52.50% 787 78.75 (78.75% 587 58.75 (58.75% 737 73.75 (73.75% 61. (61 p001 p=0.01 01 66. (66.5 52.5 (52.50 78.7 (78.75 58.7 (58.75 73.7 (73.75 (6 p00 p=0.0 (66. 52. (52.5 78. (78.7 58. (58.7 73. (73.7 ( p0 p=0. (66 (52. (78. (58. (73. p=0 (52 (78 (58 (73 p= (5 (7

Abstract Background In most cases, atherosclerotic cardiovascular disease (ACVD) is preventable through primary prevention and control of traditional risk factors, such as smoking cessation, regular physical activity, and adherence to healthy dietary patterns. The assessment of diet quality of ACVD patients would be important for a dietary intervention. Objectives This study aimed to evaluate diet quality of ACVD patients and its association with clinical conditions. Methods This cross-sectional study was nested within a randomized clinical trial entitled “Programa Alimentar Cardioprotetor Brasileiro.” Baseline data of 80 patients from Pelotas, Brazil, were obtained. Food consumption was assessed using 24-h food recall and the Revised Diet Quality Index (IQD-R). Data on smoking status and comorbidities were reported by the patients during medical history taking. To analyze the associations between IQD-R and clinical variables, unpaired Student’s t-test or the analysis of variance was performed. The significance level was 5%. Results Most of the sample consisted of men (66.5%), elderly individuals (52.50%), patients with hypertension (78.75%), dyslipidemia (58.75%), and overweight (73.75%). The average IQD-R score was 56.7 ± 12.6 points. Better quality of diet was observed for patients with diabetes compared to those without diabetes (61.1 ± 11.8 versus 54.0 ± 12.6 points; p=0.014). Conclusion There is a need to improve diet quality of ACVD patients. Patients ACVD and diabetes had better diet quality compared to those without diabetes.

ABSTRACT Objectives: Paraoxonase 1 (PON1) is an enzyme that has antioxidant potential, which confers a protective effect against the atherosclerotic process. However, studies associating genetics, dietary patterns and PON1 activity in individuals with cardiovascular disease (CVD) are scarce. Thus, the aim of the current study was to evaluate the influence of dietary factors on serum PON1 in CVD patients. Subjects and methods: Cross-sectional, sub-study of the BALANCE Program Trial. All patients aged 45 years or older and had evidence of established atherosclerotic disease in the preceding 10 years. Body weight, height, waist circumference, blood pressure, lipid profile and fasting glucose were collected. Food intake was assessed with 24-h dietary recall. Data was analyzed using SAS University Edition and a P value ≤ 0.05 was considered statistically significant. Sample was divided into three groups, according to the PON1 T(-107)C genotype (CC, CT and TT) and serum PON1 activity (Low, Medium, High). Results: There were no genotype differences for major factors. However, the systolic blood pressure was lower for CT individuals (p<0.05). Intake of cholesterol, saturated fatty acids (SFA) and monounsaturated fatty acids (MUFAS) was higher in patients with lower PON1 activity. Lipid ingestion tended to be higher in patients with lower PON1 activity (p=0.08). In the multivariate logistic regression model, SFA intake (P=0.03), genotype (P=0.09), gender (P=0.04), age (P=0.07) and carbohydrate intake (P=0.16) contributed the most to the serum PON1 activity. Conclusion: Based on these findings, nutritional guidance for these patients becomes essential, since dietary components interact with serum PON1 activity more than genotype.

Resumo O presente estudo investigou a associação entre o consumo de bebidas açucaradas e variáveis antropométricas e bioquímicas em análise transversal, realizado com dados secundários referentes à primeira consulta do ensaio clínico randomizado Dieta Cardioprotetora Brasileira (2013-2014). Foram coletados peso, altura, circunferência da cintura, perfil lipídico e glicemia de jejum e dados de um recordatório alimentar de 24 horas. Diferenças entre o consumo e não consumo de bebidas açucaradas foram avaliadas pelo teste T de student. Para analisar a associação entre o consumo de bebidas açucaradas e fatores bioquímicos e antropométricos foi utilizado o teste qui quadrado. A amostra foi de 2.172 indivíduos, sendo a maioria homens (58,5%), idosos (63,6%), do nível econômico C (57,3%), com ensino fundamental (45,8%) e com excesso de peso (62,7%). Houve associação significativa entre o consumo de bebidas açucaradas e maior valores de índice de massa corporal (p=0,029), circunferência da cintura (p=0,004) e triglicerídeos (p=0,023). Esses resultados reforçam a necessidade de intervenção nutricional quanto ao consumo de bebidas açucaradas como parte do tratamento dietético desta população.

Abstract This study investigated the association between consumption of sugar-sweetened beverages and anthropometric and biochemical variables in a cross-sectional study conducted with secondary data from the first visit of the randomized clinical trial of the Brazilian Cardioprotective Nutritional Program (BALANCE Program) (2013-2014). Weight, height, waist circumference, lipid profile and fasting glycemia and a 24-hour diet recall were collected. Differences between consumption and non-consumption of sugar-sweetened beverages were evaluated by Student’s t-test. The Chi-square test was employed to analyze the association between consumption and non-consumption of sugar-sweetened beverages and biochemical and anthropometric factors. The sample consisted of 2,172 individuals, mostly men (58.5%), elderly (63.6%), C-rated economic class (57.3%), and overweight (62.7%). A statistically significant difference was found between the consumption of sugar-sweetened beverages and higher BMI values (p=0.029), waist circumference (p=0.004) and triglycerides (p=0.023). These results emphasize the need for nutritional intervention regarding the consumption of sugar-sweetened beverages as part of the dietary treatment of this population.

Resumo O presente estudo investigou a associação entre o consumo de bebidas açucaradas e variáveis antropométricas e bioquímicas em análise transversal, realizado com dados secundários referentes à primeira consulta do ensaio clínico randomizado Dieta Cardioprotetora Brasileira (2013-2014). Foram coletados peso, altura, circunferência da cintura, perfil lipídico e glicemia de jejum e dados de um recordatório alimentar de 24 horas. Diferenças entre o consumo e não consumo de bebidas açucaradas foram avaliadas pelo teste T de student. Para analisar a associação entre o consumo de bebidas açucaradas e fatores bioquímicos e antropométricos foi utilizado o teste qui quadrado. A amostra foi de 2.172 indivíduos, sendo a maioria homens (58,5%), idosos (63,6%), do nível econômico C (57,3%), com ensino fundamental (45,8%) e com excesso de peso (62,7%). Houve associação significativa entre o consumo de bebidas açucaradas e maior valores de índice de massa corporal (p=0,029), circunferência da cintura (p=0,004) e triglicerídeos (p=0,023). Esses resultados reforçam a necessidade de intervenção nutricional quanto ao consumo de bebidas açucaradas como parte do tratamento dietético desta população.

Abstract This study investigated the association between consumption of sugar-sweetened beverages and anthropometric and biochemical variables in a cross-sectional study conducted with secondary data from the first visit of the randomized clinical trial of the Brazilian Cardioprotective Nutritional Program (BALANCE Program) (2013-2014). Weight, height, waist circumference, lipid profile and fasting glycemia and a 24-hour diet recall were collected. Differences between consumption and non-consumption of sugar-sweetened beverages were evaluated by Student’s t-test. The Chi-square test was employed to analyze the association between consumption and non-consumption of sugar-sweetened beverages and biochemical and anthropometric factors. The sample consisted of 2,172 individuals, mostly men (58.5%), elderly (63.6%), C-rated economic class (57.3%), and overweight (62.7%). A statistically significant difference was found between the consumption of sugar-sweetened beverages and higher BMI values (p=0.029), waist circumference (p=0.004) and triglycerides (p=0.023). These results emphasize the need for nutritional intervention regarding the consumption of sugar-sweetened beverages as part of the dietary treatment of this population.

O rótulo tem por função orientar o consumidor sobre os constituintes dos alimentos, promovendo escolhas alimentares saudáveis. No entanto, isto não significa que os consumidores o estejam utilizando como uma ferramenta para a escolha dos alimentos que deverão compor sua dieta e, assim, reduzir os excessos alimentares e os danos ocasionados à saúde. Este trabalho, um estudo transversal, avaliou o hábito de leitura dos rótulos de consumidores em uma rede de supermercados de Pelotas-RS. Verificou-se que 48,13% dos entrevistados avaliam os rótulos dos alimentos. Os usuários da rotulagem são, na sua maioria, mulheres, jovens e com curso superior. Houve associação significativa entre hábito de leitura e influência na compra dos produtos, o que mostra a importância da rotulagem como um instrumento no ato da compra, uma vez que representa um elo de comunicação entre o consumidor e o produto; além disso, se o rótulo é bem compreendido, permite escolhas alimentares mais criteriosas.

The label has the task of guiding the consumer on the constituents of food, promoting healthy food choices. However, this does not mean that consumers are using as a tool to choose which foods should make up your diet, and thus reduce overeating and damages health. This is a cross-sectional study, which evaluated the habit of reading labels for consumers in a supermarket chain in Pelotas, RS. It was found that 48.13% of respondents evaluate food labels. Users of labeling are mostly women, young people and university graduates. A significant association between reading habits and influence on the purchase of products, which shows the importance of labeling as a tool in the purchase, since it represents a communication link between the consumer and the product is well understood and allows choices food more insightful.

Objetivo Avaliar a influência do estado nutricional sobre a qualidade de vida em uma coorte de pacientes submetidos à quimioterapia. Métodos Avaliaram-se prospectivamente pacientes em quimioterapia de um hospital universitário de Pelotas (RS), Brasil. O estado nutricional foi avaliado por meio dos escores obtidos pela Avaliação Subjetiva Global Produzida Pelo Paciente e a qualidade de vida foi avaliada a partir da versão abreviada do questionário de qualidade de vida da Organização Mundial da Saúde. A Avaliação Subjetiva Global Produzida Pelo Paciente e o questionário de qualidade de vida foram aplicados no início e no final do estudo. Resultados Foram avaliados 143 pacientes, dos quais 76,2% eram mulheres. A prevalência de desnutrição na avaliação inicial foi de 14,0%. Observou-se que, tanto no início quanto no final do estudo, os pacientes desnutridos apresentaram pior qualidade de vida. Houve aumento do risco nutricional em 41,6% dos pacientes. Foi encontrada associação significativa entre a presença de sintomas e o aumento do risco nutricional (p<0,001). Além disso, houve correlação negativa estatisticamente significativa entre a variação dos escores do domínio físico e risco nutricional, evidenciando que conforme o risco nutricional diminui, melhora a qualidade de vida. Conclusão Conclui-se que as modificações no risco nutricional estão associadas a mudanças na qualidade de vida em pacientes com câncer. Sugere-se que o acompanhamento multidisciplinar desses pacientes poderia minimizar os efeitos colaterais do tratamento, diminuindo o risco de desnutrição, com repercussões positivas na qualidade de vida.

Objective This study aimedto evaluate the influence of nutritional status on the quality of life of a cohort of cancer patients submitted to chemotherapy. Methods Patients receiving chemotherapy for the first time in a University Hospital in Pelotas (RS), Brazil, were evaluated prospectively. Their nutritional risk was determined by the Patient-Generated Subjective Global Assessment scores and their quality of life by the World Health Organization's quality of life questionnaire, administered at the beginning and end of the study. Results One hundred and forty-three patients were studied, 76.2% being females. The prevalence of malnutrition at baseline was 14.0%. The present study found that malnourished patients had a poor quality of life. The nutritional risk of 41.6% of the patients increased after chemotherapy. A significant association was found between the presence of symptoms and increased nutritional risk (p<0.001). Additionally, there was a significant negative correlation between physical domain and nutritional risk scores, showing that quality of life increases as nutritional risk decreases. Conclusion Nutritional risk is inversely associated with quality of life in cancer patients after chemotherapy. Early nutritional interventions could minimize the side effects of treatment with a positive impact on quality of life.