Abstract Introduction: The COVID-19 pandemic required expanding the health services capacity in Brazilian states and municipalities. This study analyzed the geographic distribution of the health resources provision in the country in the period before the pandemic. Objective: This study aimed to describe the availability of health resources in the 133 intermediate geographic regions of Brazil in 2018 according to the human development index (HDI). Method: Data on population coverage of the family health strategy, number of outpatient consults and hospitalizations, public investment in health, total number of hospital beds, beds maintained by SUS, intensive care unit (ICU) beds, and ICU beds maintained by SUS were obtained from the Ministry of Health and IBGE. the association of variables with the HDI of the intermediate regions was assessed using Pearson's correlation. Results: The indices of health resources had higher average values for the South and Southeast regions, whereas the Central West ranked intermediate values. The HDI correlated positively with health resources. The coverage by family health strategy had an inverse distribution and was higher in the North and Northeast regions. Conclusions: Monitoring the health system at the intermediate region level can be a useful strategy to promote access and reduce health inequalities in Brazil. In 2018, the intermediate regions were unevenly prepared to meet their populations’ health needs and reflected the inverse care law. This scenario was the starting point for the response to the COVID-19 pandemic in 2020. Introduction COVID19 COVID 19 COVID-1 municipalities Objective 13 201 HDI. . (HDI) Method hospitalizations (ICU IBGE Pearsons Pearson s correlation Results Conclusions populations law 2020 COVID1 1 COVID- 20 (HDI 202 2

Resumo Introdução: A pandemia de COVID-19 exigiu a ampliação da capacidade dos serviços de saúde nos estados e municípios do Brasil. Este estudo analisou a distribuição geográfica da provisão de recursos de saúde no país no período que antecede essa crise sanitária. Objetivo: Descrever a provisão de recursos de saúde segundo o índice de desenvolvimento humano (IDH) das 133 regiões geográficas intermediárias do Brasil, em 2018. Método: Dados sobre cobertura populacional da Estratégia Saúde da Família, número de consultas ambulatoriais e hospitalizações, investimento público em saúde, leitos hospitalares, leitos mantidos pelo SUS, leitos de UTI e leitos de UTI mantidos pelo SUS foram obtidos junto ao Ministério da Saúde e IBGE. A associação das variáveis com o IDH das regiões intermediárias foi avaliada pela correlação de Pearson. Resultados: A provisão de recursos de saúde foi mais elevada nas regiões intermediárias do Sul e Sudeste, enquanto as regiões do Centro-Oeste tiveram valores intermediários. O IDH correlacionou positivamente com os recursos em saúde. O inverso ocorreu para a cobertura da Estratégia Saúde da Família, que foi maior nas regiões Norte e Nordeste. Conclusões: Monitorar geograficamente a provisão de recursos de saúde pode instruir estratégias para reduzir desigualdades no país. Em 2018, as regiões intermediárias estavam desigualmente preparadas para atender às necessidades em saúde de suas populações e refletiam a lei do cuidado inverso. Foi este o cenário de partida para a resposta à pandemia por COVID-19 em 2020. Introdução COVID19 COVID 19 COVID-1 Brasil sanitária Objetivo (IDH 13 2018 Método Família hospitalizações hospitalares IBGE Pearson Resultados Sudeste CentroOeste Centro Oeste intermediários Nordeste Conclusões 2020 COVID1 1 COVID- 201 202 20 2

Abstract Less-than-optimal reliability of mortality information systems regarding the underlying cause of death can mask the reality of oral (OC) and oropharyngeal cancer (OPC) mortality. This study aimed to assess the impact on the magnitude and temporal trends of OC and OPC mortality in Brazil of two statistical approaches to redistribute deaths with ill-defined underlying causes. We analyzed deaths with ill-defined causes in Brazil by macro-region, between 1996-2018. The Mortality Information System provided official information on deaths. Two correction methods were applied: the EF method, which proportionally reallocates deaths classified as R00-R99 in the ICD-10 to the remaining specific causes of death according to the proportion of deaths with certified causes; and the GBD method, which considers the concept of garbage codes, redistributing deaths from several ICD-10 chapters according to previously established coefficients. For the trend analysis of mortality (certified and redistributed), the Prais-Winsten method was carried out. The OC and OPC death rates had an evident increase after the redistribution by the two techniques in all regions of the country; the increase was higher using the GBD method. In the Northeast and North regions, this method more than doubled the certified death rates. The redistribution methods also changed time series trends. In epidemiological studies of mortality from OC and OPC, it is necessary to redistribute deaths from ill-defined causes when analyzing data from less-than-optimal information systems. The choice of the correction method is critical; epidemiological studies must manage it as a methodological decision that has significant impacts on results.

RESUMO Este é um estudo observacional, exploratório, que utilizou metodologia qualitativa, com apoio de dados quantitativos, para analisar a resposta do Sistema Único de Saúde (SUS) à Covid-19 em três municípios brasileiros. Utilizaram-se entrevistas semiestruturadas para escuta e diálogo com gestores das cidades analisadas, que foram orientadas por roteiro para explorar a percepção dos gestores durante o processo de resposta à pandemia, compreender as motivações que orientaram suas escolhas estraté- gicas e visualizar as fragilidades e potencialidades do sistema municipal em uma emergência de saúde pública. Realizou-se análise qualitativa considerando pontos-chave da resposta do SUS à pandemia, entre eles, coordenação e governança, vigilância e prevenção, e rede de serviços de saúde. Nos resultados, apresentam-se e discutem-se as principais características dos municípios, o curso da pandemia em 2020, ações de resposta adotadas; e exibe-se uma análise do padrão de resposta dos gestores do SUS municipal na pandemia.

ABSTRACT This qualitative, observational, and exploratory study was supported by quantitative data to analyze the Brazilian Unified Health System (SUS) response to Covid-19 in three Brazilian municipalities. We used semi-structured interviews to listen to and dialogue with managers of the cities analyzed, guided by a roadmap to explore the managers’ perception during the response to the pandemic, understand the motivations that guided their strategic choices, and visualize the weaknesses and potentials of the municipal system in a public health emergency. We conducted a qualitative analysis considering the critical points of the SUS response to the pandemic, including coordination and governance, surveillance and prevention, and the health services network. In the results, we present and discuss the main characteristics of the municipalities, the 2020 pandemic course, the response actions adopted, and submit an analysis of the response pattern of municipal SUS managers in the pandemic.

RESUMO Este é um estudo observacional, exploratório, que utilizou metodologia qualitativa, com apoio de dados quantitativos, para analisar a resposta do Sistema Único de Saúde (SUS) à Covid-19 em três municípios brasileiros. Utilizaram-se entrevistas semiestruturadas para escuta e diálogo com gestores das cidades analisadas, que foram orientadas por roteiro para explorar a percepção dos gestores durante o processo de resposta à pandemia, compreender as motivações que orientaram suas escolhas estraté- gicas e visualizar as fragilidades e potencialidades do sistema municipal em uma emergência de saúde pública. Realizou-se análise qualitativa considerando pontos-chave da resposta do SUS à pandemia, entre eles, coordenação e governança, vigilância e prevenção, e rede de serviços de saúde. Nos resultados, apresentam-se e discutem-se as principais características dos municípios, o curso da pandemia em 2020, ações de resposta adotadas; e exibe-se uma análise do padrão de resposta dos gestores do SUS municipal na pandemia.

ABSTRACT This qualitative, observational, and exploratory study was supported by quantitative data to analyze the Brazilian Unified Health System (SUS) response to Covid-19 in three Brazilian municipalities. We used semi-structured interviews to listen to and dialogue with managers of the cities analyzed, guided by a roadmap to explore the managers’ perception during the response to the pandemic, understand the motivations that guided their strategic choices, and visualize the weaknesses and potentials of the municipal system in a public health emergency. We conducted a qualitative analysis considering the critical points of the SUS response to the pandemic, including coordination and governance, surveillance and prevention, and the health services network. In the results, we present and discuss the main characteristics of the municipalities, the 2020 pandemic course, the response actions adopted, and submit an analysis of the response pattern of municipal SUS managers in the pandemic.

ABSTRACT OBJECTIVE to discuss the impact four different redistribution strategies have on the quantitative and temporal trends of cancer mortality assessment in Brazil. METHODOLOGY This study used anonymized and georeferenced data provided by the Brazilian Ministry of Health (BMoH). Four different approaches were used to conduct the redistribution of ill-defined deaths and garbage codes. Age-standardized mortality rates used the world population as reference. Prais-Winsten autoregression allowed the calculation of region, sex, and cancer type trends. RESULTS Death rates increased considerably in all regions after redistribution. Overall, Elisabeth B. França’s and the World Health Organization methods had a milder impact on trends and rate magnitudes when compared to the Global Burden of Disease (GBD) 2010 method. This study also observed that, when the BMoH dealt with the problem of redistributing ill-defined deaths, results were similar to those obtained by the GBD method. The redistribution methods also influenced the assessment of trends; however, differences were less pronounced. CONCLUSIONS Since developing a comparative gold standard is impossible, matching global techniques to local realities may be an alternative for methodological selection. In our study, the compatibility of the findings suggests how valid the GBD method is to the Brazilian context. However, caution is needed. Future studies should assess the impact of these methods as applied to the redistribution of deaths to type-specific neoplasms.

ABSTRACT OBJECTIVE to discuss the impact four different redistribution strategies have on the quantitative and temporal trends of cancer mortality assessment in Brazil. METHODOLOGY This study used anonymized and georeferenced data provided by the Brazilian Ministry of Health (BMoH). Four different approaches were used to conduct the redistribution of ill-defined deaths and garbage codes. Age-standardized mortality rates used the world population as reference. Prais-Winsten autoregression allowed the calculation of region, sex, and cancer type trends. RESULTS Death rates increased considerably in all regions after redistribution. Overall, Elisabeth B. França’s and the World Health Organization methods had a milder impact on trends and rate magnitudes when compared to the Global Burden of Disease (GBD) 2010 method. This study also observed that, when the BMoH dealt with the problem of redistributing ill-defined deaths, results were similar to those obtained by the GBD method. The redistribution methods also influenced the assessment of trends; however, differences were less pronounced. CONCLUSIONS Since developing a comparative gold standard is impossible, matching global techniques to local realities may be an alternative for methodological selection. In our study, the compatibility of the findings suggests how valid the GBD method is to the Brazilian context. However, caution is needed. Future studies should assess the impact of these methods as applied to the redistribution of deaths to type-specific neoplasms.

RESUMO O objetivo deste estudo foi caracterizar e analisar os diferentes métodos existentes para a avaliação de programas e serviços de alimentação e nutrição no Brasil, por meio de revisão sistemática da literatura focada em artigos completos publicados em revistas indexadas nacionais. Foi realizada uma pesquisa nas bases de dados PubMed, MedLine e LILACS utilizando os seguintes termos de busca e operadores booleanos: “avaliação e programa”; “projeto”; “intervenção”; “serviço”; “ações e nutrição”; “nutricional”. A pesquisa foi restrita a artigos escritos em português, inglês e espanhol e publicados entre 2001 e 2015. Vinte e dois estudos foram selecionados e a análise indica; a maioria foi realizada por meio de abordagens quantitativas e avaliações externas baseadas na teoria epidemiológica; as estratégias de avaliação participativa ainda são incomuns; as avaliações de impacto e implementação foram predominantes; há pouca diversidade em termos de referências ao arcabouço teórico no campo da avaliação de programas de atenção à saúde no planejamento e execução dos processos de avaliação analisados. Os resultados deste estudo indicam a necessidade de uma avaliação mais abrangente, considerando a complexidade das intervenções avaliadas utilizando o aparato teórico-metodológico disponível na literatura para compreender a importância das diferentes perspectivas dos agentes envolvidos nos processos de avaliação.

ABSTRACT The objective of this study was to characterize and analyze the different existing methods for the evaluation of food and nutrition programs and services in Brazil, through a systematic review of the literature focused on complete articles published in national indexed journals. We searched the PubMed, MedLine and LILACS databases using the following search terms and Boolean operators: “evaluation and program”; “project”; “intervention”; “servisse”; “actions and nutrition”; “nutritional”. The research was restricted to articles written in Portuguese, English and Spanish and published between 2001 and 2015. Twenty-two studies were selected and the analysis indicates; most were carried out through quantitative approaches and external evaluations based on epidemiological theory; participatory evaluation strategies are still uncommon; Impact assessments and implementation were predominant; there is little diversity in terms of references to the theoretical framework in the field of evaluation of health care programs in the planning and execution of the evaluation processes analyzed. The results of this study indicate the need for a more comprehensive evaluation considering the complexity of the interventions evaluated using the theoretical-methodological apparatus available in the literature to understand the importance of the different perspectives of the agents involved in the evaluation processes.