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Safety of two-dose schedule of COVID-19 adsorbed inactivated vaccine (CoronaVac; Sinovac/Butantan) and heterologous additional doses of mRNA BNT162b2 (Pfizer/BioNTech) in immunocompromised and immunocompetent individuals
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Miyaji, Karina Takesaki

; Ibrahim, Karim Yaqub

; Infante, Vanessa

; Moreira, Raquel Megale

; Santos, Carolina Ferreira dos Belizário, Juliana de Cássia Pinto, Maria Isabel de Moraes Marinho, Ana Karolina Barreto Berselli Pereira, Juliana Marquezi Mello, Liliane Saraiva de Silva, Vitor Gabriel Lopes da Sato, Paula Keiko Strabelli, Tânia Mara Varejão Ragiotto, Lucas Pacheco, Pedro Henrique Theotonio de Mesquita Braga, Patricia Emilia Loch, Ana Paula Precioso, Alexander Roberto Sartori, Ana Marli Christovam França, João Ítalo Lima, Marcos Alves de Ando, Mauricio Cesar Sampaio Rodrigues, Camila Cristina Martini Song, Alice Tung Wan Lara, Amanda Nazareth Belizário, Ana Cristina Lima, Anna Helena Simões Bortulucci de Zanetti, Ariane Cristina Barboza Paulo, Audrey Rose da Silveira Amancio de Rosa, Barbara Miranda dos Santos Moraes, Bruna Del Guerra de Carvalho Oliveira, Bruna Ribeiro de Picone, Camila de Melo Aranda, Carolina Sanches Troli, Carolinne Paioli Kokron, Cristina M. Terrabuio, Debora Raquel Benedita Abdala, Edson David Neto, Elias Nakanishi, Érika Yoshie Shimoda Lima, Fabiana Mascarenhas Souza Firmino, Fabio Batista Santos, Fernanda Barone Alves dos Bacal, Fernando Fatobene, Giancarlo Santana, Jaqueline Oliveira Kalil, Jorge Barbosa, Julia Gonçalves, Leandro Peres Otuyama, Leonardo Jun Pierrotti, Ligia Camera Compte, Livia Caroline Mariano Marinho, Livia Chaer, Livia Netto Seguro, Luis Fernando Azevedo, Luiz Sergio Ueda, Márcia Aiko Terreri, Maria Teresa Barros, Myrthes Anna Maragna Toledo Grecco, Octávio Sejas, Odeli Nicole Encinas Musqueira, Priscila Tavares Ito, Raquel Keiko de Luca Teixeira, Samia Silveira Souza Fidalgo, Serafim Costa, Silvia Figueiredo Campos, Silvia Vidal Fernandes, Tamiris Hinsching Rocha, Vanderson Geraldo Coelho, Vivian Caso

Revista do Instituto de Medicina Tropical de São Paulo

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2025, Volume 67 elocation e2

Resumo: En | Texto: En | PDF: En

ABSTRACT Immunocompromised individuals were considered high-risk for severe disease due to SARS COV-2 infection. This study aimed to describe the safety of two doses of COVID-19 adsorbed inactivated vaccine (CoronaVac; Sinovac/Butantan), followed by additional doses of mRNA BNT162b2 (Pfizer/BioNTech) in immunocompromised (IC) adults, compared to immunocompetent/healthy (H) individuals. This phase 4, multicenter, open label study included solid organ transplant and hematopoietic stem cell transplant recipients, cancer patients and people with inborn errors of immunity with defects in antibody production, rheumatic, end-stage chronic kidney or liver disease, who were enrolled in the IC group. Participants received two doses of CoronaVac and additional doses of mRNA BNT162b2. Adverse reactions (AR) data were collected within seven days after each vaccination. Serious adverse events and of special interest (AESI) were monitored throughout the study. We included 241 immunocompromised and 100 immunocompetent subjects. Arthralgia, fatigue, myalgia, and nausea were more frequent in the IC group after CoronaVac. Following the first additional dose of mRNA BNT162, pain, induration, and tenderness at injection site, fatigue and myalgia were more frequent in the H group. A heart transplant recipient had a graft rejection temporally associated with the second CoronaVac dose, but there was no literature evidence of causal association. Four cases of AESI were considered related to the vaccine: three erythema multiforme after CoronaVac, all in IC participants, and one paresthesia after mRNA, in a H participant. Our findings were comparable to other studies that evaluated the safety of COVID-19 vaccines in different immunocompromised populations. Both vaccines were safe for immunocompromised participants.

https://doi.org/10.1590/s1678-9946202567002

FACILE HYDROTHERMAL SYNTHESIS OF NIOBIUM PENTOXIDE SEMICONDUCTOR AND THEIR APPLICATION IN THE PHOTODEGRADATION OF DYES AND REDUCTION OF FREE FAT ACIDS IN WASTE OIL
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Crisóstomo, Camilo Aurélio Brandão

; Damacenoa, Fernanda Barbos

; Barbosa, Luele Ribeiro de Sousa

; Almeida, Jânio Santos Batista, Walker Vinicius Ferreira do Carmo Malagutti, Andréa Renata Mesquita, João Paulo de Torres, Juliana Arriel Iga, Gustavo Duran Oliveira, Caue Ribeiro de Ribeiro, Roberto Ananias Mourão, Henrique A. J. L.

Química Nova

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2025, Volume 48 Nº 1 elocation e-20250015

Resumo: En | Texto: En | PDF: En

We report a facile hydrothermal method for the synthesis of niobium pentoxide (Nb2O5) under two different temperatures, 120 °C (Nb2O5-120) and 150 °C (Nb2O5-150). The obtained materials were characterized by structural, optical and morphological techniques. Also, the photocatalytic properties of the Nb2O5 samples were evaluated in two reactions under ultraviolet (UVC) irradiation: degradation of methylene blue (MB) and indigo carmine (IC) dyes; and esterification of free fatty acids (FFA) present in waste cooking oil (WCO). The Nb2O5 was formed at different temperatures of synthesis, and the increase in temperature did not cause significant changes in the structural and optical characteristics, but resulted in an increased surface area of the synthesized materials. Both synthesized materials showed excellent efficiency for dye photodegradation. The sample Nb2O5-150 presented the best performance for the MB photodegradation, with almost 85% of the removal efficiency. In this case, the adsorption of MB molecules on the surface of the material was high due to the favorable electrostatic interaction and also because of its high surface area. For the IC photodegradation, the adsorption was insignificant, and both samples presented approximately 100% of the removal efficiency. These materials were also promising for the reduction of free fat acids in waste oil by photoesterification. NbO Nb O (Nb2O5 12 C Nb2O5120 (Nb2O5-120 15 Nb2O5150. Nb2O5150 . (Nb2O5-150) techniques Also Nb2O UVC (UVC irradiation (MB (IC dyes FFA (FFA WCO. WCO (WCO) characteristics photodegradation Nb2O5-15 85 case insignificant 100 photoesterification (Nb2O 1 Nb2O512 (Nb2O5-12 Nb2O515 (Nb2O5-150 (WCO Nb2O5-1 8 10 Nb2O51 (Nb2O5-1 (Nb2O5-15 Nb2O5- (Nb2O5-

https://doi.org/10.21577/0100-4042.20250015

O legado de Celso Furtado
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BATISTA JR., PAULO NOGUEIRA

Brazilian Journal of Political Economy

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Jan 2024, Volume 44 Nº 1 Páginas 29 - 41

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

ABSTRACT This essay reviews Celso Furtado’s intellectual legacy, highlighting his enormous importance for economic thought. It adopts the method of comparing Furtado to another great Brazilian economist, Mário Henrique Simonsen, emphasizing the superiority of the former over the latter in several essential aspects. It also discusses the relation of Furtado to Keynes and the Keynesian economic tradition, on the one hand, and to Marx and Marxism, on the other. It highlights, in conclusion, his links to nationalism and romanticism, expressed in his attachment to Brazil.

RESUMO Este ensaio recapitula o legado intelectual de Celso Furtado, destacando sua enorme importância para o pensamento econômico. Adota o recurso de comparar Furtado a outro grande economista brasileiro, Mário Henrique Simonsen, ressaltando a superioridade do primeiro em relação ao segundo em diversos aspectos essenciais. Discute, também, a relação de Furtado com Keynes e a tradição econômica keynesiana, de um lado, e com o Marx e o marxismo, de outro. Ressalta, em conclusão, a sua ligação com o nacionalismo e o romantismo, expresso no seu apego ao Brasil.

https://doi.org/10.1590/0101-31572024-3601

Electronic medical record for audiological monitoring of occupational noise exposure
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Perini, Beatriz Peixoto

; Rocha, Clayton Henrique

; Said, Giselle Carvalho

; Gomes, Julia Batista Correa

; Moreira, Renata Rodrigues

; Samelli, Alessandra Giannella

Revista CEFAC

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2024, Volume 26 Nº 4 elocation e3124

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

ABSTRACT Purpose: to develop and implement an electronic medical record for managing audiological assessments of workers exposed to occupational noise at a university. Methods: a computer system - the Electronic Audiology Record Program (PPVA, in Portuguese) - was developed with Microsoft Access for a university hospital’s audiology service, encompassing functional, occupational, and audiological information. After a testing period, the system was implemented in the service. Results: the PPVA is a personalized system that registers employees, audiological exams, clinical history, and risks for hearing loss induced by high sound pressure levels. It also generates reports indicating audiological monitoring frequency. Conclusion: the PPVA proved to meet the service’s needs, adequately. Its implementation improved the usability, efficiency, and quality of the service user records. Hence, it is a potential health surveillance tool, indicating that this type of instrument can benefit occupational hearing loss prevention programs. Purpose Methods PPVA, (PPVA Portuguese hospitals hospital s functional information period Results employees exams history levels frequency Conclusion services needs adequately usability efficiency records Hence tool programs

RESUMO Objetivos: desenvolver e implementar um prontuário virtual para gerenciamento das avaliações audiológicas de trabalhadores expostos ao ruído ocupacional de uma universidade. Métodos: foi desenvolvido um sistema informatizado para um serviço de audiologia de um hospital universitário de São Paulo, o Programa de Prontuários Virtuais de Audiologia (PPVA), utilizando o programa Microsoft Access, onde foram incluídas informações funcionais, ocupacionais e audiológicas. Após período de testes, o sistema foi implementado no serviço. Resultados: o PPVA é um sistema personalizado, no qual é possível realizar o cadastro de funcionários, exames audiológicos, histórico clínico e de riscos para perda auditiva induzida por níveis de pressão sonora elevados, além da geração de relatórios indicando a periodicidade para o monitoramento audiológico. Conclusão: o PPVA mostrou-se adequado para atender às demandas do serviço. Sua implementação trouxe melhorias na usabilidade, eficiência e qualidade do registro dos usuários do serviço, sendo também uma potencial ferramenta de vigilância em saúde, indicando que este tipo de ferramenta pode trazer benefícios para um programa de prevenção de perdas auditivas ocupacionais. Objetivos universidade Métodos Paulo PPVA, , (PPVA) Access funcionais testes Resultados personalizado funcionários audiológicos elevados audiológico Conclusão mostrouse mostrou se usabilidade saúde (PPVA

https://doi.org/10.1590/1982-0216/20242643124

Analysis of peri-implant bone tissue between hydrophilic and rough implant surfaces in spontaneously hypertensive rats treated with losartan periimplant peri
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SANTOS, Jaqueline Silva dos

; MULINARI-SANTOS, Gabriel

; DE SOUZA BATISTA, Fábio Roberto

; GOMES-FERREIRA, Pedro Henrique Silva

; PALIN, Letícia Pitol

; ANTONIALI, Cristina

; OKAMOTO, Roberta

Journal of Applied Oral Science

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2024, Volume 32 elocation e20230374

Resumo: En | Texto: En | PDF: En

Abstract Hypertensive individuals present alterations in their calcium metabolism that consequently decrease the concentration of this mineral in the bone tissue. Objectives to evaluate the morphological and functional characteristics of the peri-implant bone tissue that was formed during the healing process by the placement implants using two different surface treatments: hydrophilic Acqua™ (ACQ) and rough NeoPoros™ (NEO), in spontaneously hypertensive (SHR) and normotensive rats (Wistar) whether or not treated with losartan. Methodology In total, 96 male rats (48 Wistar and 48 SHR) were divided into eight subgroups: absolute control rough (COA NEO), absolute control hydrophilic (COA ACQ), losartan control rough (COL NEO), losartan control hydrophilic (COL ACQ), SHR absolute rough (SHR NEO), SHR absolute hydrophilic (SHR ACQ), SHR losartan rough (SHRL NEO), and SHR losartan hydrophilic (SHRL ACQ). The rats medicated with losartan received daily doses of the medication. NeoPoros™ and Acqua™ implants were installed in the tibiae of the rats. After 14 and 42 days of the surgery, the fluorochromes calcein and alizarin were injected in the rats. The animals were euthanized 67 days after treatment. The collected samples were analyzed by immunohistochemistry, biomechanics, microcomputerized tomography, and laser confocal scanning microscopy analysis. Results The osteocalcin (OC) and vascular endothelium growth factor (VEGF) proteins had moderate expression in the SHRL ACQ subgroup. The same subgroup also had the highest implant removal torque. Regarding microarchitectural characteristics, a greater number of trabeculae was noted in the control animals that were treated with losartan. In the bone mineralization activity, it was observed that the Acqua™ surface triggered higher values of MAR (mineral apposition rate) in the COA, COL, and SHRL groups (p<0.05). Conclusion the two implant surface types showed similar responses regarding the characteristics of the peri-implant bone tissue, even though the ACQ surface seems to improve the early stages of osseointegration. periimplant peri treatments Acqua (ACQ NeoPoros NEO, NEO , (NEO) (Wistar total 9 (4 4 subgroups COA NEO) ACQ, ACQ) COL ACQ. . medication 1 surgery 6 treatment immunohistochemistry biomechanics tomography analysis OC (OC VEGF (VEGF torque activity rate p<0.05. p005 p p<0.05 0 05 (p<0.05) osseointegration (NEO ( p00 p<0.0 (p<0.05 p0 p<0. (p<0.0 p<0 (p<0. p< (p<0 (p< (p

https://doi.org/10.1590/1678-7757-2023-0374

Prevalence of Congenital Anomalies of the Upper Limbs in Brazil: a descriptive cross-sectional study Brazil crosssectional cross sectional
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Moura, Samuel Ricardo Batista

; Nakachima, Luis Renato

; Santos, João Baptista Gomes dos

; Belloti, João Carlos

; Fernandes, Carlos Henrique

; Faloppa, Flavio

; Moraes, Vinicius Ynoe de

; Sabongi, Rodrigo Guerra

Sao Paulo Medical Journal

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2024, Volume 142 Nº 6 elocation e2023349

Resumo: En | Texto: En | PDF: En

ABSTRACT BACKGROUND: Congenital Anomalies of the Upper Limb (CAUL) are a group of structural or functional abnormalities that develop during intrauterine life and can lead to limb dysfunction. OBJECTIVES: To analyze the prevalence of congenital anomalies of the upper limbs in Brazil and assess maternal and neonatal variables. DESIGN AND SETTING: A cross-sectional, descriptive study was conducted on congenital upper limb malformations among live births across Brazil. METHODS: The study spanned from 2010 to 2019. Data were sourced from the Department of Informatics of the Unified Health System (DATASUS) and the Live Birth Information System (SINASC) portal. Analyses focused on the information reported in field 41 of the Live Birth Declaration Form entered into the computerized system. RESULTS: The most common anomaly in Brazil was supernumerary fingers, classified as ICD-Q69.0, affecting 11,708 children, with a prevalence of 4.02 per 10,000 live births. Mothers aged over 40 years had a 36% higher prevalence of having children with CAUL than mothers under 40 years old (OR = 1.36; 95% CI 1.19-1.56). Newborns weighing ≥ 2,499 g were 2.64 times more likely to have CAUL compared to those weighing ≥ 2,500 g (OR = 2.64; 95% CI 2.55-2.73). CONCLUSION: There was an observed increase in the reporting of CAUL cases over the decade studied. This trend serves as an alert for health agencies, as understanding the prevalence of CAUL and its associated factors is crucial for preventive medicine. BACKGROUND (CAUL dysfunction OBJECTIVES variables SETTING crosssectional, crosssectional cross sectional, sectional cross-sectional METHODS 201 2019 DATASUS (DATASUS SINASC (SINASC portal 4 system RESULTS fingers ICDQ69.0, ICDQ690 ICDQ ICD Q69.0, Q69 0 Q ICD-Q69.0 11708 11 708 11,70 402 02 4.0 10000 10 000 10,00 36 OR 1.36 136 1 95 1.191.56. 119156 1.19 1.56 . 19 56 1.19-1.56) 2499 2 499 2,49 264 64 2.6 2500 500 2,50 2.552.73. 255273 2.55 2.73 55 73 2.55-2.73) CONCLUSION studied agencies medicine 20 ICDQ69 ICDQ69.0 Q690 Q69.0 Q6 ICD-Q69. 1170 70 11,7 4. 1000 00 10,0 3 1.3 13 9 191 1.191.56 11915 119 1.1 156 1.5 5 1.19-1.56 249 49 2,4 26 6 2. 250 50 2,5 552 2.552.73 25527 255 2.5 273 2.7 7 2.55-2.73 ICDQ6 ICDQ69. Q69. ICD-Q69 117 11, 100 10, 1. 1.191.5 1191 15 1.19-1.5 24 2, 25 2.552.7 2552 27 2.55-2.7 ICD-Q6 1.191. 1.19-1. 2.552. 2.55-2. ICD-Q 1.191 1.19-1 2.552 2.55-2 1.19- 2.55-

https://doi.org/10.1590/1516-3180.2023.0349.r1.08042024

Longitudinal data collection in pediatric and adult patients with 5q spinal muscular atrophy in Latin America: LATAM RegistrAME study - a clinical registry study protocol q America
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Batista, Elice Carneiro

; Zanoteli, Edmar

; Monfardini, Frederico

; Santos, Gustavo Prado dos

; Silva, Gisele Sampaio

; Berwanger, Otávio

; Rizzo, Luiz Vicente

; Fonseca, Henrique Andrade Rodrigues da

einstein (São Paulo)

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2024, Volume 22 elocation eAE1133

Resumo: En | Texto: En | PDF: En

ABSTRACT Spinal muscular atrophy is a rare hereditary neurodegenerative disease characterized by progressive motor neuron loss. The most common form of SMA is linked to 5q (5q-SMA) and is classified into subtypes according to the age of onset and maximum motor function achieved. The severity ranges from progressive infantile paralysis and premature death (type 1) to limited motor neuron loss in adults (type 4). The LATAM RegistrAME protocol is an observational, retrospective, prospective international multicenter clinical registry study involving Latin Americans. We will include 5q-SMA patients across all age groups, from pediatric to adult, to describe their clinical characteristics and disease progression. The protocol will use an international clinical research form based on the Treat Neuromuscular Disease Global Academic Network (TREAT-NMD), which focuses on advancing research on neuromuscular disorders in patients with spinal muscular atrophy. The study will include six countries in Latin America, sampling a total of 415 patients with SMA and 5q-SMA types 1, 2, 3, and 4 of all ages and both sexes who have genetically confirmed 5q-SMA. The mean follow-up period was 24 months. The primary outcomes will be the description of general clinical characteristics, access to medications capable of modifying the course of the disease, functional assessments, motor milestones, and ventilatory support. This study will provide insights into 5q spinal muscular atrophy patients in Latin America to better understand their clinical characteristics, use of medications, and outcomes while supporting further clinical management protocols and clinical trials. ClinicalTrials.gov Identifier: NCT05475691. q 5qSMA qSMA (5q-SMA achieved type 1 4. . 4) observational retrospective Americans groups adult progression TREATNMD, TREATNMD TREAT NMD , (TREAT-NMD) 41 2 3 5qSMA. SMA. followup follow up months assessments milestones support trials ClinicalTrialsgov ClinicalTrials gov Identifier NCT05475691 NCT (TREAT-NMD NCT0547569 NCT054756 NCT05475 NCT0547 NCT054 NCT05 NCT0

https://doi.org/10.31744/einstein_journal/2024ae1133

Borboletas e mariposas (Lepidoptera) da Ilha do Cardoso, Estado de São Paulo, Brasil Lepidoptera (Lepidoptera Cardoso Paulo
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Freitas, André Victor Lucci

; Siewert, Ricardo Russo

; Rosa, Augusto Henrique Batista

; Moraes, Simeão Souza

; Oliveira, Thiago de

; Mielke, Olaf Hermann Hendrik

; Brown Jr, Keith Spalding

Hoehnea

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2024, Volume 51 elocation e112024

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

ABSTRACT (Butterfly and moths (Lepidoptera) from Ilha do Cardoso, São Paulo State, Brazil). The present paper presents a preliminary list of species of butterflies and moths (Lepidoptera) from the Ilha do Cardoso, Cananéia Municipality, in the south of the State of São Paulo, SE Brazil. The list has 245 recorded butterfly species, 118 Hesperiidae, 78 Nymphalidae, 19 Lycaenidae, 17 Riodinidae, 9 Pieridae and 4 Papilionidae. In addition to these, 15 species of diurnal moths have been recorded so far. Based on comparisons with lists from nearby locations, the list could exceed 500 butterfly species with greater sampling effort. Even with a relatively preliminary list, based on some better-sampled subgroups, the Cardoso Island region shows a fauna typical of the coastal region between the States of São Paulo and Santa Catarina. Taking into account that the diversity of butterflies and moths must be mirrored by other groups of insects, vertebrates, and plants, the “Ilha do Cardoso” has enormous importance in preserving the biodiversity of the southern region of São Paulo State. Butterfly Lepidoptera (Lepidoptera Brazil . Brazil) Municipality 24 11 Hesperiidae 7 Nymphalidae 1 Lycaenidae Riodinidae Papilionidae these far locations 50 effort bettersampled better sampled subgroups Catarina insects vertebrates plants 2 5

RESUMO (Borboletas e mariposas (Lepidoptera) da Ilha do Cardoso, Estado de São Paulo, Brasil). O presente trabalho apresenta uma lista preliminar das espécies de borboletas e mariposas (Lepidoptera) da Ilha do Cardoso, no Município de Cananéia, no sul do Estado de São Paulo, no sudeste do Brasil. A lista conta com 245 espécies de borboletas registradas, sendo 118 Hesperiidae, 78 Nymphalidae, 19 Lycaenidae, 17 Riodinidae, 9 Pieridae e 4 Papilionidae. Além dessas, 15 espécies de mariposas diurnas foram registradas até o momento. Baseado em comparações com listas de localidades próximas, a lista pode passar das 500 espécies de borboletas com um maior esforço amostral. Mesmo com uma lista relativamente preliminar, com base em alguns subgrupos mais bem amostrados, a região da Ilha do Cardoso mostra uma fauna típica da região costeira entre os Estados de São Paulo e Santa Catarina. Levando-se em conta que a diversidade de borboletas e mariposas deve ser espelhada por outros grupos de insetos, vertebrados e plantas, a Ilha do Cardoso tem enorme importância na preservação da biodiversidade da região sul do Estado de São Paulo. Borboletas Lepidoptera (Lepidoptera Brasil . Brasil) Cananéia 24 11 Hesperiidae 7 Nymphalidae 1 Lycaenidae Riodinidae Papilionidae dessas momento próximas 50 amostral amostrados Catarina Levandose Levando se insetos plantas 2 5

https://doi.org/10.1590/2236-8906e112024

Privações múltiplas e homicídios: o caso da Região Metropolitana de São Paulo (2001-2018)
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Batista, Henrique Rogê

Economia e Sociedade

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Mai 2023, Volume 32 Nº 2 Páginas 483 - 505

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

Abstract The dynamics of the homicide rate in Brazil between 2001-2018 presents a trajectory of a certain stability, configuring itself as a chronic problem with economic and social developments. In this scenario, the Metropolitan Region of São Paulo (RMSP) stands out from the others for the drop in this rate and for presenting the lowest value at the end of the analyzed period. At the same time, the RMSP also saw a reduction in the multiple deprivation of its individuals. With this in mind, this work aims to evaluate the evolution of these multiple deprivations in the RMSP and to relate it to the homicide rate. In short, it observed that the situation of deprivation is multidimensional and determines the individual’s potential for criminal practice; of the selected variables, education and the individual’s condition of not studying nor having any income are those that have the greatest positive elasticities with the homicide rate; and the risks of punishing illegal activity discourages its practice.

Resumo A dinâmica da taxa de homicídios no Brasil entre 2001-2018 apresenta uma trajetória de certa estabilidade configurando-se como um problema crônico com desdobramentos econômicos e sociais. Neste cenário, a Região Metropolitana de São Paulo (RMSP) se destaca das demais pela queda dessa taxa e por apresentar o menor valor no final do período analisado. Paralelamente, a RMSP também assistiu ao decréscimo da privação múltipla dos seus indivíduos. Tendo isso em vista, este trabalho objetivou avaliar a evolução destas privações múltiplas na RMSP e sua relação com a taxa de homicídios. Em suma, observa-se que a situação de privação é multidimensional e determina a potencialidade do indivíduo para a prática criminal; das variáveis selecionadas, a educação e a condição do indivíduo de não estudar e nem possuir renda são as que apresentam maiores elasticidades positivas com a taxa de homicídios e; os riscos de punição da atividade ilegal desincentivam a sua prática.

https://doi.org/10.1590/1982-3533.2023v32n2art10

10.

Salivary protein candidates for biomarkers of oral disorders in people with a crack cocaine use disorder
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CHAIBEN, Cassiano Lima

; MACEDO, Nayara Flores

; BATISTA, Thiago Beltrami Dias PENTEADO, Carlos Antonio Schaffer VENTURA, Talita M. O. DIONIZIO, Aline SOUZA, Paulo Henrique Couto BUZALAF, Marília Afonso Rabelo AZEVEDO-ALANIS, Luciana Reis

Journal of Applied Oral Science

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2023, Volume 31 elocation e20220480

Resumo: En | Texto: En | PDF: En

Abstract The use of cocaine and its main derivative, crack, can cause some systemic effects that may lead to the development of some oral disorders. Objective To assess the oral health of people with a crack cocaine use disorder and identify salivary protein candidates for biomarkers of oral disorders. Methodology A total of 40 volunteers hospitalized for rehabilitation for crack cocaine addiction were enrolled; nine were randomly selected for proteomic analysis. Intraoral examination, report of DMFT, gingival and plaque index, xerostomia, and non-stimulated saliva collection were performed. A list of proteins identified was generated from the UniProt database and manually revised. Results The mean age (n=40) was 32 (±8.88; 18–51) years; the mean DMFT index was 16±7.70; the mean plaque and gingival index were 2.07±0.65 and 2.12±0.64, respectively; and 20 (50%) volunteers reported xerostomia. We identified 305 salivary proteins (n=9), of which 23 were classified as candidate for biomarkers associated with 14 oral disorders. The highest number of candidates for biomarkers was associated with carcinoma of head and neck (n=7) and nasopharyngeal carcinoma (n=7), followed by periodontitis (n=6). Conclusions People with a crack cocaine use disorder had an increased risk of dental caries and gingival inflammation; less than half had oral mucosal alterations, and half experienced xerostomia. As possible biomarkers for 14 oral disorders, 23 salivary proteins were identified. Oral cancer and periodontal disease were the most often associated disorders with biomarkers. derivative 4 enrolled analysis examination xerostomia nonstimulated non stimulated performed revised n=40 n40 n (n=40 3 ±8.88 888 8 88 (±8.88 18–51 1851 18 51 years 16±7.70 16770 16 7 70 207065 2 07 0 65 2.07±0.6 212064 12 64 2.12±0.64 respectively 50% 50 (50% 30 n=9, n9 n=9 , 9 (n=9) 1 n=7 n7 (n=7 n=7, n=6. n6 n=6 . 6 (n=6) inflammation alterations n=4 n4 (n=4 ±8.8 (±8.8 18–5 185 5 16±7.7 1677 20706 2.07±0. 21206 2.12±0.6 (50 n= (n=9 (n= (n=6 ±8. (±8. 18– 16±7. 167 2070 2.07±0 2120 2.12±0. (5 (n ±8 (±8 16±7 207 2.07± 212 2.12±0 ( ± (± 16± 2.07 21 2.12± 2.0 2.12 2. 2.1

https://doi.org/10.1590/1678-7757-2022-0480

11.

Schistosomiasis of liver graft as a differential diagnosis of abnormal liver tests after transplantation: report of two cases transplantation
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Falcão, Lydia Teófilo de Moraes

; Batista, Andrea Dória Maranhão, Erika Cavalcante Santos, Siglya Soares Ferreira dos Madeiro, Vitor Ribeiro Viana Moura, Fabio Mesquita Lyra, Cesar Henrique Alves

Revista do Instituto de Medicina Tropical de São Paulo

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2023, Volume 65 elocation e2

Resumo: En | Texto: En | PDF: En

ABSTRACT Schistosomiasis is a major health problem that affects over 200 million people worldwide. There are few reports of Schistosoma mansoni found in liver transplants as well as scarce information about the course of the disease and the long-term effects on the graft. Herein, we report two cases of schistosomiasis in liver transplant recipients who presented abnormal serum liver enzymes, with evidence of gradual improvement after antiparasitic treatment. Furthermore, we discuss the possible role of screening the parasite infection in potential liver transplant recipients from endemic areas. 20 worldwide longterm long term graft Herein enzymes treatment Furthermore areas 2

https://doi.org/10.1590/s1678-9946202365002

12.

Diretriz Brasileira de Dispositivos Cardíacos Eletrônicos Implantáveis – 2023 202 20 2
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Teixeira, Ricardo Alkmim

; Fagundes, Alexsandro Alves

; Baggio Junior, José Mário

; Oliveira, Júlio César de

; Medeiros, Paulo de Tarso Jorge

; Valdigem, Bruno Pereira

; Teno, Luiz Antônio Castilho

; Silva, Rodrigo Tavares

; Melo, Celso Salgado de

; Elias Neto, Jorge

; Moraes Júnior, Antonio Vitor

; Pedrosa, Anisio Alexandre Andrade

; Porto, Fernando Mello

; Brito Júnior, Hélio Lima de

; Souza, Thiago Gonçalves Schroder e

; Mateos, José Carlos Pachón

; Moraes, Luis Gustavo Belo de

; Forno, Alexander Romeno Janner Dal

; D’Avila, Andre Luiz Buchele

; Cavaco, Diogo Alberto de Magalhães

; Kuniyoshi, Ricardo Ryoshim

; Pimentel, Mauricio

; Camanho, Luiz Eduardo Montenegro

; Saad, Eduardo Benchimol

; Zimerman, Leandro Ioschpe

; Oliveira, Eduardo Bartholomay

; Scanavacca, Mauricio Ibrahim

; Martinelli Filho, Martino

; Lima, Carlos Eduardo Batista de

; Peixoto, Giselle de Lima

; Darrieux, Francisco Carlos da Costa Duarte, Jussara de Oliveira Pinheiro Galvão Filho, Silas dos Santos Costa, Eduardo Rodrigues Bento Mateo, Enrique Indalécio Pachón Melo, Sissy Lara De Rodrigues, Thiago da Rocha Rocha, Eduardo Arrais Hachul, Denise Tessariol Lorga Filho, Adalberto Menezes Nishioka, Silvana Angelina D’Orio Gadelha, Eduardo Barreto Costa, Roberto Andrade, Veridiana Silva de Torres, Gustavo Gomes Oliveira Neto, Nestor Rodrigues de Lucchese, Fernando Antonio Murad, Henrique Wanderley Neto, José Brofman, Paulo Roberto Slud Almeida, Rui M. S. Leal, João Carlos Ferreira

Arquivos Brasileiros de Cardiologia

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2023, Volume 120 Nº 1 elocation e20220892

Resumo: Pt | Texto: Pt | PDF: Pt

https://doi.org/10.36660/abc.20220892

13.

Contribution of public oral pathology services to the diagnosis of oral and oropharyngeal cancer in Brazil
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LOUREDO, Brendo Vinicius Rodrigues

; CURADO, Maria Paula

; PENAFORT, Paulo Victor Mendes

; DE ARRUDA, José Alcides Almeida

; ABREU, Lucas Guimarães

; MESQUITA, Ricardo Alves

; PINTO-JÚNIOR, Décio dos Santos

; ABRAHÃO, Aline Corrêa

; ANDRADE, Bruno Augusto Benevenuto de

; AGOSTINI, Michelle

; MORAES, Renata Mendonça

; ANBINDER, Ana Lia

; DOURADO, Pedro Henrique Silva

; SANTOS, Teresa Cristina Ribeiro Bartholomeu dos

; PIRES, Fábio Ramoa

; BORDIGNON, Natalia Cristina Trentin

; GONDAK, Rogério Oliveira

; DE OLIVEIRA, Marcia Gaiger

; CARRARD, Vinicius Coelho

; MARTINS, Manoela Domingues

; SOUSA-NETO, Sebastião Silvério

; ARANTES, Diego Antônio Costa

; MENDONÇA, Elismauro Francisco

; CIESLAK-SANCHES, Silvia Roberta

; ANTUNES, Daniella Moraes

; AMARAL-SILVA, Gleyson Kleber do

; MANIERI, Patricia Rubia

; RAMALHO, Luciana Maria Pedreira

; DOS SANTOS, Jean Nunes

; LEONEL, Augusto César Leal da Silva

; PEREZ, Danyel Elias da Cruz

; VERHEUL, Hannah Carmem Carlos Ribeiro Silva

; BARROSO, Keila Martha Amorim

; RODRIGUES, Flávia Luiza Santos

; GONZAGA, Amanda Katarinny Goes

; FERNANDES, Romana Renery

; DE SOUZA, Lélia Batista

; SOUZA, Lucas Lacerda de

; PONTES, Flávia Sirotheau Corrêa

; PONTES, Hélder Antônio Rebelo

; SILVA, Caroline Alfaia

; CÂMARA, Jeconias

; LIBÓRIO-KIMURA, Tatiana Nayara

; SANTOS-SILVA, Alan Roger

; LOPES, Márcio Ajudarte

; ALMEIDA, Oslei Paes de

; ROMAÑACH, Mário José

; VARGAS, Pablo Agustin

Brazilian Oral Research

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2023, Volume 37 elocation e126

Resumo: En | Texto: En | PDF: En

Abstract This study aimed to evaluate the contribution of oral and maxillofacial pathology laboratories (OMPLs) in Brazilian public universities to the diagnosis of lip, oral cavity, and oropharyngeal squamous cell carcinoma (SCC). A cross-sectional study was performed using biopsy records from a consortium of sixteen public OMPLs from all regions of Brazil (North, Northeast, Central-West, Southeast, and South). Clinical and demographic data of patients diagnosed with lip, oral cavity, and oropharyngeal SCC between 2010 and 2019 were collected from the patients’ histopathological records. Of the 120,010 oral and maxillofacial biopsies (2010-2019), 6.9% (8,321 cases) were diagnosed as lip (0.8%, 951 cases), oral cavity (4.9%, 5,971 cases), and oropharyngeal (1.2%, 1,399 cases) SCCs. Most cases were from Brazil’s Southeast (64.5%), where six of the OMPLs analyzed are located. The predominant profile of patients with lip and oral cavity SCC was Caucasian men, with a mean age over 60 years, low schooling level, and a previous history of heavy tobacco consumption. In the oropharyngeal group, the majority were non-Caucasian men, with a mean age under 60 years, had a low education level, and were former/current tobacco and alcohol users. According to data from the Brazilian National Cancer Institute, approximately 9.9% of the total lip, oral cavity, and oropharyngeal SCCs reported over the last decade in Brazil may have been diagnosed at the OMPLs included in the current study. Therefore, this data confirms the contribution of public OMPLs with respect to the important diagnostic support they provide to the oral healthcare services extended by the Brazilian Public Health System.

https://doi.org/10.1590/1807-3107bor-2023.vol37.0126

14.

Prediction of the basic density of tropical woods by near-infrared spectroscopy
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Medeiros, Dayane Targino de

; Melo, Rafael Rodolfo de

; Cademartori, Pedro Henrique Gonzalez de

; Batista, Felipe Gomes

; Mascarenhas, Adriano Reis Prazeres

; Scatolino, Mário Vanoli

; Hein, Paulo Ricardo Gherardi

CERNE

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2023, Volume 29 elocation e-103262

Resumo: En | Texto: En | PDF: En

ABSTRACT Background: Determining the basic density of the wood is usually defined as a simple process, but it requires caution and the operator’s skill to avoid errors in the analysis. In addition, it involves sample preparation and time to saturate the wood until obtaining the dry sample mass. The development of alternative measurement techniques could reduce the time to obtain the results and provide reliable values. Therefore, this study aimed to develop multivariate models to estimate the basic density of native woods using near-infrared spectra (NIR). Basic densities were determined by the water immersion method, and the values were associated with NIR signatures. Spectra were directly collected on the wood transversal and radial faces with an integrating sphere. Partial least squares regression (PLS-R) was calibrated and validated to estimate basic density based on spectral signatures. Results: In the cross-validation and prediction of the models, the results were promising. The coefficients of determination varied from 0.87 to 0.93 with a standard error of 0.01 %. The partial least squares discriminant analysis (PLS-DA) efficiently classified the wood species. The ratio of performance to deviation obtained satisfactory values, a minimum of 2.81 and a maximum of 4.20. Conclusion: The statistical parameters of the models based on NIR spectra showed potential for density measurements in floors, furniture, and solid wood products.

https://doi.org/10.1590/01047760202329013262

15.

PARALLELIZATION OF SHORTEST PATH CLASS ALGORITHMS: A COMPARATIVE ANALYSIS
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Souza, Flávio Henrique Batista de

; Abreu, Marcos Henrique Gonçalves

; Trindade, Paulo Ricardo Fonseca

; Fernandes, Gustavo Alves

; Carvalho, Luiz Melk de

; Couto, Braulio Roberto Gomes Marinho

; Rodrigues, Diva de Souza e Silva

Pesquisa Operacional

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2023, Volume 43 elocation e272130

Resumo: En | Texto: En | PDF: En

ABSTRACT The problem of finding the shortest path between a source and a destination node, commonly represented by graphs, has several computational algorithms as an attempt to find what is called the minimum path. Depending on the number of nodes in-between the source and destination, the process of finding the shortest path can demand a high computational cost (with polynomial complexity). A solution to reduce the computational cost is the use of the concept of parallelism, which divides the algorithm tasks between the processing cores. This article presents a comparative analysis of the main algorithms of the shortest path class: Dijkstra, Bellman-Ford, Floyd-Warshall and Johnson. The performance of each algorithm was evaluated considering different parallelization approaches and they were applied on general and open-pit mining databases present in the literature. The experimental results showed an improvement in performance of about 55% on the execution time depending on the chosen parallelization point.

https://doi.org/10.1590/0101-7438.2023.043.00272130

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