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Abstract Introduction Juvenile nasopharyngeal angiofibroma (JNA) is a benign vascularized tumor that affects almost exclusively male adolescents. Surgery is the treatment of choice for JNA. Objectives The present study is a 42-year retrospective review of a series of JNA cases treated surgically without previous embolization. Methods The present is a retrospective, descriptive study based on medical records of 96 patients with JNA who underwent microscopic or endoscopic excision without previous embolization from 1978 to 2020 in a single institution. The patients were categorized according to the Andrews et al. stage, and data were collected on age, gender, tumor staging, surgical approach, affected side, and outcome. Results All patients were male, with an average age of 17 years. The predominant tumor stage consisted of type II, with 52.1%. A total of 33.3% of the patients were submitted to the microscopic technique and 66.7%, to the endonasal technique. The rate of intraoperative blood transfusion was of 17.7%. Conclusion The present study reinforces that resection of JNA in various stages is viable without previous artery embolization. (JNA adolescents 42year year 42 9 197 202 institution al gender staging approach side outcome 1 years II 521 52 52.1% 333 33 3 33.3 667 66 7 66.7% 177 17.7% 4 19 20 5 52.1 33. 6 66.7 17.7 2 52. 66. 17.

https://doi.org/10.1055/s-0043-1777293

Effect of 12 weeks of strength training on the static balance of the elderly 1
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Cardoso, Mateus Ibraim

; Coelho, Izabela Silva

; Souza, Perciliany Martins de

; Silva, Ana Carolina da

; Rosse, Izinara Cruz

; Ferreira Júnior, João Batista

; Becker, Lenice Kappes

; Oliveira, Emerson Cruz de

; Coelho, Daniel Barbosa

Revista Brasileira de Cineantropometria & Desempenho Humano

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2024, Volume 26 elocation e86319

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

Abstract Aging has a direct impact on balance due to changes in sensory and motor response, sarcopenia, reduced muscle strength and range of motion that occur in the elderly. In this context, strength training (ST) programs are seen as a valuable strategy to minimize the deleterious effect of aging on strength production and balance in this population. The purpose of the study was to evaluate the effect of 12 weeks of progressive intensity ST on static balance variables in the elderly. The study included 23 elderly with an average age of 65±8.61 years, of both sexes, who performed a twelve-week strength training program, with a frequency of three times a week and with progressive intensity (60 - 85% of 1-RM). Balance was assessed before and after the intervention period, through stabilometric assessment on a force plate. After the intervention, there was a reduction in the anteroposterior amplitude (p=0.01), in the anteroposterior velocity (p=0.01) and in the total displaced area (p=0.04). It is concluded that the strength training can be used as a key tool to minimize the deleterious effect of aging on the maintenance of static balance. response sarcopenia context (ST population 1 2 65861 65 8 61 65±8.6 years sexes twelveweek twelve program 60 (6 85 1RM. 1RM RM . 1-RM) period plate p=0.01, p001 p p=0.01 , 0 01 (p=0.01 p=0.04. p004 p=0.04 04 (p=0.04) 6586 6 65±8. ( 1-RM p00 p=0.0 (p=0.0 (p=0.04 658 65±8 p0 p=0. (p=0. 65± p=0 (p=0 p= (p= (p

Resumo O envelhecimento tem impacto direto no equilíbrio devido a alterações da resposta sensorial e motora, sarcopenia e redução da força muscular e da amplitude de movimento que ocorre nos idosos. Nesse contexto, programas de treinamento de força (TF) são vistos como valiosa estratégia para minimizar o efeito deletério do envelhecimento na produção de força e no equilíbrio dessa população. O objetivo do estudo foi avaliar o efeito de 12 semanas de TF com intensidade progressiva sobre as variáveis de equilíbrio estático em idosos. Participaram do estudo 23 idosos com idade média de 65±8,61 anos, de ambos os sexos, que realizaram um programa de TF de doze semanas, com frequência de três vezes por semana e com intensidade progressiva (60 - 85% de 1-RM). O equilíbrio foi avaliado antes e após o período de intervenção, por meio de avaliação estabilométrica em plataforma de força. Após a intervenção houve redução na amplitude anteroposterior (p=0,01), na velocidade anteroposterior (p=0,01) e na área total deslocada (p= 0,04). Conclui-se que o treinamento de força pode ser utilizado como ferramenta chave para minimizar o efeito deletério do envelhecimento na manutenção do equilíbrio estático. motora contexto (TF população 1 2 65861 65 8 61 65±8,6 anos sexos 60 (6 85 1RM. 1RM RM . 1-RM) p=0,01, p001 p p=0,01 , 0 01 (p=0,01 p= (p 0,04. 004 0,04 04 0,04) Concluise Conclui se 6586 6 65±8, ( 1-RM p00 p=0,0 (p=0,0 00 0,0 658 65±8 p0 p=0, (p=0, 0, 65± p=0 (p=0

https://doi.org/10.1590/1980-0037.2024v26e86319

Efficiency of mixed and rigid occlusal stabilization splints: Randomized clinical trial splints
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OPPITZ, Layza Rossatto

; ARANTES, Ana Carolina Mastriani

; GARANHANI, Roberto Ramos

; COSTA, Carlos Alberto

; ARAUJO, Cristiano Miranda de

; TANAKA, Orlando Motohiro

; ANDREIS, Patricia Kern di Scala

; SCHAPPO, Claudia

; IGNÁCIO, Sérgio Aparecido

; JOHANN, Aline Cristina Batista Rodrigues

; RACHED, Rodrigo Nunes

; CAMARGO, Elisa Souza

Brazilian Oral Research

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2024, Volume 38 elocation e017

Resumo: En | Texto: En | PDF: En

Abstract Occlusal stabilization splints are the most common treatment for controlling the deleterious effects of sleep bruxism. This study aimed to evaluate the effectiveness of a low-cost, mixed occlusal splint (MOS) compared to that of a rigid splint. A randomized clinical trial was performed on 43 adults of both sexes with possible sleep bruxism and satisfactory dental conditions. They were divided into rigid occlusal splint (ROS) (n = 23) and MOS (n = 20) groups. Masticatory muscle and temporomandibular joint (TMJ) pain intensity (visual analog scale), quality of life (WHOQOL-BREF), indentations in the oral mucosa, anxiety, and depression (HADS), number of days of splint use, and splint wear were evaluated. All variables were evaluated at baseline (T0), 6 months (T6), and 12 months (T12) after splint installation (T0), and splint wear was evaluated at T6 and T12. Student’s t-test, Mann–Whitney U test, non-parametric Friedman’s analysis of variance for paired samples and pairwise multiple comparisons, Pearson’s chi-square test, two-proportion z-test, non-parametric McNemar’s and Cochran’s Q, and Wilcoxon tests were used (p < 0.05). In both groups, there was a decrease in TMJ pain and pain intensity over time and improvements in the quality of life scores. At T6, there was a higher rate of splint wear in the MOS group than in the ROS group (p = 0.023). The MOS showed a higher rate of wear than the rigid splint but had similar results for the other variables. Therefore, the use of a mixed splint appears to be effective in controlling the signs and symptoms of sleep bruxism. lowcost, lowcost low cost, cost low-cost (MOS 4 conditions (ROS n 23 20 groups (TMJ visual scale, scale , scale) WHOQOLBREF, WHOQOLBREF WHOQOL BREF (WHOQOL-BREF) mucosa anxiety HADS, HADS (HADS) T0, T0 T (T0) (T6) 1 T12 (T12 Students Student s ttest, ttest t test t-test MannWhitney Mann Whitney nonparametric non parametric Friedmans Friedman comparisons Pearsons Pearson chisquare chi square twoproportion two proportion ztest, ztest z z-test McNemars McNemar Cochrans Cochran Q p 0.05. 005 0.05 . 0 05 0.05) scores 0.023. 0023 0.023 023 0.023) Therefore 2 (WHOQOL-BREF (HADS (T0 (T6 T1 (T1 00 0.0 002 0.02 02 (T 0.

https://doi.org/10.1590/1807-3107bor-2024.vol38.0017

Prognostic value of programmed cell death ligand 1 (PD-L1) expression in patients with stage III non-small cell lung cancer under different treatment types: a retrospective study PDL1 PDL PD L1 L (PD-L1 nonsmall non small types (PD-L
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Castro, Nicoly Marques de

; Moura, Fernando

; Hada, Aline Lury

; Garcia, Diogo

; Victor, Elivane da Silva

; Schvartsman, Gustavo

; Carvalho, Leonardo

; Fernandes, Milena Lourenço Coleta

; Martins, Rodrigo de Souza

; Silva, Elaine Ferreira da

; Santos, Sarah Silva Mello Batista dos

; Taniwaki, Letícia

; Taranto, Patrícia

; Pontes, Janaina

; Beal, Juliana Rodrigues

; Dutra, Ana Carolina Pereira

; Oliveira Filho, João Bosco de

; Araujo, Sérgio Eduardo Alonso

; Usón Junior, Pedro Luiz Serrano

einstein (São Paulo)

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2024, Volume 22 elocation eAO0575

Resumo: En | Texto: En | PDF: En

ABSTRACT Objective Currently programmed cell death protein 1 (PD-1) inhibitors in combination with other therapies are being evaluated to determine their efficacy in cancer treatment. However, the effect of PD-ligand (L) 1 expression on disease outcomes in stage III (EC III) non-small cell lung cancer is not completely understood. Therefore, this study aimed to assess the influence of PD-L1 expression on the outcomes of EC III non-small cell lung cancer. Methods This study was conducted on patients diagnosed with EC III non-small cell lung cancer who underwent treatment at a tertiary care hospital. PD-L1 expression was determined using immunohistochemical staining, all patients expressed PD-L1. Survival was estimated using the Kaplan-Meier method. Relationships between variables were assessed using Cox proportional regression models. Results A total of 49 patients (median age=69 years) with EC III non-small cell lung cancer and PD-L1 expression were evaluated. More than half of the patients were men, and most were regular smokers. The patients were treated with neoadjuvant chemotherapy, surgery, or sequential or combined chemotherapy and radiotherapy. The median progression-free survival of the entire cohort was 14.2 months, and the median overall survival was 20 months. There was no significant association between PD-L1 expression and disease progression, clinical characteristics, or overall survival. Conclusions PD-L1 expression was not correlated with EC III non-small cell lung cancer outcomes. Whether these findings differ from the association with immune checkpoint inhibitors remains to be addressed in future studies. PD1 PD (PD-1 However PDligand ligand L (L nonsmall non small understood Therefore PDL1 PDL L1 PD-L hospital staining PDL1. L1. KaplanMeier Kaplan Meier method models 4 age69 age 69 age=6 years men smokers surgery radiotherapy progressionfree progression free 142 14 2 14. months characteristics studies (PD- age6 6 age= (PD

https://doi.org/10.31744/einstein_journal/2024ao0575

Can habits and behaviors predict colonization by community-associated MRSA in patients admitted to a Brazilian hospital? communityassociated community associated hospital
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Pinheiro, Marcos Vinicius de Barros

; Cavalcante, Fernanda Sampaio

; Ferreira, Dennis de Carvalho

; Guimarães, Ana Carolina Fonseca

; Ferreira, Adriana Lúcia Pires

; Costa, Claudia Regina da

; Santos, Kátia Regina Netto dos

; Nouér, Simone Aranha

; Rangel, Ana Pereira

; Castiñeiras, Anna Carla

; Gonzalez, Christiany Moçali

; Freire, Joana

; Guimarães, Luiz Felipe

; Batista, Raquel

Revista do Instituto de Medicina Tropical de São Paulo

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2024, Volume 66 elocation e31

Resumo: En | Texto: En | PDF: En

ABSTRACT This study aimed to identify factors associated with colonization by community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) in adult patients admitted to a Brazilian hospital. This is a cross-sectional study, in which patients underwent a nasal swab and were asked about hygiene behavior, habits, and clinical history. Among the 702 patients, 180 (25.6%) had S. aureus and 21 (2.9%) MRSA. The factors associated with MRSA colonization were attending a gym (OR 4.71; 95% CI; 1.42 – 15.06), smoking habit in the last year (OR 2.37; 95% CI; 0.88 – 6.38), previous hospitalization (OR 2.18; CI 95%; 0.89 – 5.25), and shared personal hygiene items (OR 1.99; 95% CI; 0.71 – 5.55). At the time of admission, colonization by CA-MRSA isolates was higher than that found in the general population. This can be an important public health problem, already endemic in hospitals, whose factors such as those associated with habits (smoking cigarettes) and behaviors (team sports practice and activities in gyms) have been strongly highlighted. These findings may help developing infection control policies, allowing targeting patients on higher-risk populations for MRSA colonization. communityassociated community methicillinresistant methicillin resistant CAMRSA CA (CA-MRSA hospital crosssectional cross sectional behavior history 70 18 25.6% 256 25 6 (25.6% S 2 2.9% 29 9 (2.9% OR 4.71 471 4 71 95 142 1 42 1.4 15.06, 1506 15.06 , 15 06 15.06) 2.37 237 37 088 0 88 0.8 6.38, 638 6.38 38 6.38) 2.18 218 089 89 5.25, 525 5.25 5 5.25) 1.99 199 99 071 0.7 5.55. 555 5.55 . 55 5.55) admission population problem hospitals cigarettes team gyms highlighted policies higherrisk risk 7 25.6 (25.6 2.9 (2.9 4.7 47 14 1. 150 15.0 2.3 23 3 08 8 0. 63 6.3 2.1 52 5.2 1.9 19 07 5.5 25. (25. 2. (2. 4. 15. 6. 5. (25 (2 (

https://doi.org/10.1590/s1678-9946202466031

Revisores 2023
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Molas de la Quintana, Adriana Beatriz

; Jimenez Genchi, Alejandro

; Carrizales, Alexia

; Gotti, Amanda

; Martinez Ortiz, Ana

; Rocío Martínez Yacelga, Ana del

; Camilo Ciantelli, Ana Paula

; Jimenez Figueroa, Andres

; Neumann, Angélica Paula

; Parodi Svartman, Bernardo

; Vazquez Rodriguez, Carolina

; Da Silva, Cecilia

; Baroni, Cecilia

; Lanza Perez, Cintia Beatriz

; Mola, Débora

; Alarcón Rubio, David

; Perales Mejia, Felipe de Jesús

; Sarachu, Gerardo

; Gelpi, Gonzalo

; Sosa, Gustavo

; Viana Batista, Helder

; Moizéis, Heloísa Bárbara Cunha

; Carrasco, Jimena

; Ungaretti, Joaquín

; Moreira, Karen

; Tomatis, Karina

; Oros, Laura Beatriz

; Mazaro, Lisabelle Manente

; Chiavone, Luciana

; Perilla Toro, Lyria Esperanza

; Campagnoli, Mabel Alicia

; Ruiz Barbot, Mabela

; Brenlla, María Elena

; Folle Chavannes, María Ana

; Freytes Frey, Marcela

; Rossal, Marcelo

; Ortiz, Maria Victoria

; Nabergoi, Mariela

; Montenegro, Marisela

; Lladó, Mónica

; Freitas De León, Paribanú

; Solís García, Patricia

; Ruiz Santos, Paul

; Fiorati, Regina Célia

; Martins, Rita de Cássia Andrade

; Dominguez-Lara, Sergio Alexis

; Herranz, Silvana Melisa

; Yoma, Solana María

; Gondim, Sonia Maria Guedes

; Rostagnol, Susana

; Wittke, Tommy

; Ballesteros, Virginia

; Tamayo, William

Psicología, Conocimiento y Sociedad

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Dez 2023, Volume 13 Nº 3 Páginas 116 - 118

Resumo: Es | Texto: Es | PDF: Es

https://doi.org/10.26864/pcs.v13.n3.rev

King’s Parkinson’s Disease Pain Questionnaire: reliability and convergent construct validity Kings King s Parkinsons Parkinson Questionnaire
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Sartori, Ana Carolina

; Santos, Fânia Cristina dos

; Lopes, Juliana de Lima

; Santos, Vinicius Batista

; Okuno, Meiry Fernanda Pinto

Revista Brasileira de Enfermagem

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2023, Volume 76 Nº 3 elocation e20220379

Resumo: Es En Pt | Texto: Es En Pt | PDF: Es | PDF: En | PDF: Pt

RESUMEN Objetivos: evaluar las evidencias de confiabilidad y validez convergente de constructo del King’s Parkinson’s Disease Pain Questionnaire. Métodos: estudio psicométrico con 75 adultos mayores con enfermedad de Parkinson. El instrumento fue aplicado por dos investigadores por separado y vuelto a aplicar por uno investigador después de 15 días. En cuanto a la confiabilidad, se evaluó la consistencia interna mediante la prueba alfa de Cronbach y la estabilidad mediante el coeficiente de correlación intraclase. Al evaluar la validez del constructo, las puntuaciones del King’s Parkinson’s Disease Pain Questionnaire se compararon con las de la Geriatric Pain Measure. Resultados: se obtuvo un alfa de Cronbach promedio entre las tres evaluaciones por encima de 0,60 y correlación intraclase por encima de 0,90, y una correlación débil pero significativa entre las dos escalas aplicadas. Conclusiones: el instrumento mostró evidencia adecuada de validez convergente de constructo y confiabilidad, y puede ser utilizado en la práctica clínica. Objetivos Kings King s Parkinsons Parkinson Métodos 7 1 días Measure Resultados 060 0 60 0,6 090 90 0,90 aplicadas Conclusiones clínica 06 6 0, 09 9 0,9

ABSTRACT Objectives: to assess the evidence of reliability and convergent construct validity of the King’s Parkinson’s Disease Pain Questionnaire. Methods: psychometric study of 75 older adults with Parkinson’s disease. The instrument was applied by two researchers separately and reapplied by one researcher 15 days later. In terms of reliability, internal consistency was assessed using the Cronbach’s alpha test and stability using the intraclass correlation coefficient. Scores of the King’s Parkinson’s Disease Pain Questionnaire were compared to those of the Geriatric Pain Measure in the assessment of construct validity. Results: the mean Cronbach’s alpha obtained between the three assessments was above 0.60, the intraclass correlation between the three assessments was above 0.90, and there was a weak but significant correlation between the two applied scales. Conclusions: the instrument showed adequate evidence of convergent construct validity and reliability, and can be used in clinical practice. Objectives Kings King s Parkinsons Parkinson Methods 7 disease 1 later Cronbachs Cronbach coefficient Results 060 0 60 0.60 090 90 0.90 scales Conclusions practice 06 6 0.6 09 9 0.9 0.

RESUMO Objetivos: avaliar as evidências de confiabilidade e de validade de construto convergente do King’s Parkinson’s Disease Pain Questionnaire. Métodos: estudo psicométrico com 75 idosos com doença Parkinson. O instrumento foi aplicado por dois pesquisadores separadamente e reaplicado por um dos pesquisadores após 15 dias. Na confiabilidade, a consistência interna foi avaliada pelo teste de alfa de Cronbach e a estabilidade pelo coeficiente de correlação intraclasse. Na avaliação da validade de construto, os escores do King’s Parkinson’s Disease Pain Questionnaire foram comparados ao escore da Geriatric Pain Measure. Resultados: foi obtido um alfa de Cronbach médio entre as três avaliações acima de 0,60 e correlação intraclasse entre as três avaliações acima de 0,90, bem como uma correlação fraca, mas significativa entre as duas escalas aplicadas. Conclusões: o instrumento apresentou adequadas evidências de validade de construto convergente e de confiabilidade, podendo ser utilizado na prática clínica. Objetivos Kings King s Parkinsons Parkinson Métodos 7 1 dias Measure Resultados 060 0 60 0,6 090 90 0,90 fraca aplicadas Conclusões clínica 06 6 0, 09 9 0,9

https://doi.org/10.1590/0034-7167-2022-0379

A MULTICRITERIA DECISION MODEL FOR RISK MANAGEMENT MATURITY EVALUATION
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Yoshiura, Luiz Junior Maemura

; Martins, Carolina Lino

; Costa, Ana Paula Cabral Seixas

; Santos-Neto, João Batista Sarmento dos

Pesquisa Operacional

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2023, Volume 43 elocation e270186

Resumo: En | Texto: En | PDF: En

ABSTRACT This article aims to present a Multicriteria Decision Aiding (MCDA) model for assessing risk management maturity. Therefore, it is proposed to use a Maturity Model (MM) for risk management aligned with the ELECTRE TRI method. The ELECTRE TRI was chosen as the sorting method because it has a strong axiomatic structure based on the relationship of concordance and discordance between the alternative and the profile that delimits each of its classes. To test the proposal, a case study was carried out on a real company in the construction industry. For the development of the risk management maturity assessment model, a questionnaire was applied to collect data related to risk management practices in the organization. After collection, the data were used for modeling in a Decision Support System to apply the ELECTRE TRI, which managed to classify and identify the organization’s risk management maturity at level 3 (managed). MCDA (MCDA Therefore MM (MM classes proposal industry organization collection organizations s managed. . (managed) (managed

https://doi.org/10.1590/0101-7438.2023.043.00270186

Ensino de segurança do paciente na pandemia da covid-19: percepção de estudantes de enfermagem covid19 covid 19 covid-19 covid1 1 covid-1 covid-
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Pereira, Ana Carolina Simões

; Batista, Taynara de Oliveira Farias

; Costa, Maria Antonia Ramos

; Matsuda, Laura Misue

; Spigolon, Dandara Novakowski

; Souza, Verusca Soares de

Escola Anna Nery

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2023, Volume 27 elocation e20220279

Resumo: Es En Pt | Texto: Es En Pt | PDF: Es | PDF: En | PDF: Pt

Resumen Objetivo Aprehender la percepción de los estudiantes de curso técnico y superior de enfermería sobre la enseñanza de competencias en seguridad del paciente en la pandemia del COVID-19. Método Estudio cualitativo, realizado en 2021, con estudiantes de Enfermería de nivel técnico y superior en Paraná, mediante entrevistas individuales. Se utilizó la técnica del análisis de contenido. Resultados Surgieron las siguientes categorías: Comprensión del concepto de seguridad del paciente, reforzada por la práctica clínica; Actitudes y sentimientos hacia los cuasi accidentes, los acontecimientos adversos y la práctica insegura y; Reflejos negativos de la pandemia del COVID-19 sobre la educación en seguridad del paciente. Conclusión e implicaciones para la práctica La enseñanza de competencias en seguridad del paciente fue percibida por los estudiantes con sentimientos negativos debido a la experiencia de cuasi accidentes, eventos adversos y prácticas inseguras. Debido a la pandemia del COVID-19, denunciaron fragmentación en la enseñanza de la materia objeto de estudio, alejamiento de la práctica y, en consecuencia, inseguridad académica y profesional. La profundización del debate sobre la enseñanza de competencias en materia de seguridad del paciente durante la pandemia es esencial para la calidad de la formación y el desempeño profesional. COVID19. COVID19 COVID 19. 19 cualitativo 2021 Paraná individuales contenido categorías clínica accidentes COVID-1 inseguras COVID19, 19, estudio consecuencia profesional COVID1 1 202 COVID- 20 2

Abstract Objective To apprehend the perception of technical and undergraduate nursing students about the teaching of patient safety competencies in the pandemic of COVID-19. Method Qualitative study, conducted in 2021, with technical and undergraduate nursing students from Paraná, through individual interviews. The content analysis technique was used. Results The following categories emerged: Understanding of the concept of patient safety enhanced by clinical practice; Attitudes and feelings towards near miss, adverse events and unsafe practice and; Negative reflexes of the COVID-19 pandemic on patient safety teaching. Conclusion and implications for practice The teaching of patient safety competencies was perceived by students with negative feelings due to the experience of near misses, adverse events and unsafe practices. Due to the pandemic of COVID-19, they reported fragmentation in the teaching of the subject under study, distance from practice and, consequently, academic and professional insecurity. Further discussion of the teaching of patient safety competencies during the pandemic is indispensable to the quality of training and professional performance. COVID19. COVID19 COVID 19. 19 study 2021 Paraná interviews used emerged miss COVID-1 misses practices COVID19, 19, consequently insecurity performance COVID1 1 202 COVID- 20 2

Resumo Objetivo Apreender a percepção de discentes de curso técnico e superior de Enfermagem sobre o ensino das competências de segurança do paciente na pandemia da COVID-19. Método Estudo qualitativo, realizado em 2021, com estudantes de Enfermagem de nível técnico e superior do Paraná, por meio de entrevistas individuais. Utilizou-se técnica de análise de conteúdo. Resultados Emergiram as categorias: Compreensão do conceito segurança do paciente potencializada pela prática clínica; Atitudes e sentimentos frente ao near miss, evento adverso e prática insegura e; Reflexos negativos da pandemia da COVID-19 no ensino da segurança do paciente. Conclusão e implicações para a prática O ensino das competências de segurança do paciente foi apreendido pelos estudantes com sentimentos negativos pela vivência de near miss, eventos adversos e práticas inseguras. Devido à pandemia da COVID-19, referiram fragmentação no ensino do tema em estudo, distanciamento da prática e; consequentemente, insegurança acadêmica e profissional. O aprofundamento da discussão do ensino das competências de segurança do paciente durante a pandemia é indispensável à qualidade de formação e atuação profissional. COVID19. COVID19 COVID 19. 19 qualitativo 2021 Paraná individuais Utilizouse Utilizou se conteúdo categorias clínica miss COVID-1 inseguras COVID19, 19, estudo consequentemente profissional COVID1 1 202 COVID- 20 2

https://doi.org/10.1590/2177-9465-ean-2022-0279pt

10.

The influence of fluoxetine on orthodontic tooth movement in rats
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MARIN, Gabriela Costa

; JOHANN, Aline Cristina Batista Rodrigues

; SILVA, Isteicy Cortêz

; ARANTES, Ana Carolina Mastriani

; HARDY, Ana Maria Trindade Grégio

; IGNÁCIO, Sergio Aparecido

; TANAKA, Orlando Motohiro

; GUARIZA FILHO, Odilon

; CAMARGO, Elisa Souza

Brazilian Oral Research

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2023, Volume 37 elocation e007

Resumo: En | Texto: En | PDF: En

Abstract This study aimed to evaluate the effects of chronic use of fluoxetine on the amount of orthodontic tooth movement and tissue changes in rats. A total of 192 Wistar rats were divided into 4 groups: S, 0.9% saline solution; F, 20 mg/kg of fluoxetine; SM, 0.9% saline solution with orthodontic movement; and FM, 20 mg/kg of fluoxetine with orthodontic movement. After 30 days of daily saline or fluoxetine administration, an orthodontic device (25cN) was used to mesially displace the first molar in animals of the groups SM and FM. The animals were euthanized 2, 7, 14, and 28 days after placement of the orthodontic appliances and animals of groups S and F were euthanized at the same time. The assessment of tooth movement was made in gypsum castings, the collagen neoformation was assessed by polarization microscopy, the number of osteoclasts and root resorption were evaluated using tartrate-resistant acid phosphatase, and presence of hyalinized areas was assessed by hematoxylin-eosin staining. Fluoxetine did not affect the amount of tooth displacement, percentage of collagen, number of osteoclasts, and presence of hyalinized areas (P>0.05). There was a higher frequency of root resorption areas in the FM group than in the SM group only on the second day (P<0.05). The findings of this study show that chronic use of 20 mg/kg fluoxetine does not affect the amount of tooth movement, collagen neoformation, number of osteoclasts, or hyalinized areas and does not affect root resorption until the last day of orthodontic movement. 19 09 0 9 0.9 2 mgkg mg kg 3 administration 25cN cN (25cN 7 14 time castings microscopy tartrateresistant tartrate resistant phosphatase hematoxylineosin hematoxylin eosin staining displacement P>0.05. P005 P P>0.05 . 05 (P>0.05) P<0.05. P<0.05 (P<0.05) 1 0. P00 P>0.0 (P>0.05 P<0.0 (P<0.05 P0 P>0. (P>0.0 P<0. (P<0.0 P>0 (P>0. P<0 (P<0. P> (P>0 P< (P<0 (P> (P< (P

https://doi.org/10.1590/1807-3107bor-2023.vol37.0007

11.

Eye diseases associated with psoriatic arthritis in the Amazon
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Allen, Thaís Suellen Ramos

; Leão, Jaqueline Azevedo

; Souza, Bruna Cavaleiro de Macêdo

; Freitas, Ana Carolina Batista Pamplona de

; Koyama, Robson Seiji Tsuchiyama

; Koyama, Roberta Vilela Lopes

Arquivos Brasileiros de Oftalmologia

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Out 2022, Volume 85 Nº 5 Páginas 459 - 464

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: Descrever as manifestações oftalmológicas observadas em pacientes com artrite psoriásica atendidos no Serviço de Reumatologia da Universidade do Estado do Pará. Métodos: Estudo transversal. A amostra foi composta por 23 pacientes com artrite psoriásica, segundo os critérios de Caspar, atendidos no ambulatório de reumatologia da Universidade do Estado do Pará. Para avaliação da atividade de doença foi aplicado o Clinical Disease Activity index for Psoriatic Arthritis e, posteriormente, foi realizado o exame oftalmológico (acuidade visual com correção para distância, biomicroscopia, tonometria de aplanação de Goldmann, fundoscopia, teste de Schirmer I, tempo de ruptura do filme lacrimal, lissamina verde e questionário The Ocular Surface Disease Index). Resultados: Nesta pesquisa não houve predomínio entre os sexos e a população tinha uma mediana de idade de 47,78 anos. As manifestações mais comuns foram olho seco (60,9%), catarata (56,5%), blefarite (47,8%), ceratite (43,5%), meibomite (30,4%) e pterígio (26,1%). Conclusão: As manifestações oculares encontradas em pacientes com artrite psoriásica são variadas e afetam sobretudo a superfície ocular; no entanto, são clinicamente subestimadas; por isso recomenda-se o acompanhamento oftalmológico regular e periódico para pacientes com artrite psoriásica.

ABSTRACT Purpose: Ocular disorders are among the most frequent manifestations of psoriatic arthritis. The incidence, type, and severity of these disorders may be influenced by genetics, local environmental factors, and access to ophthalmic treatment. Here we describe the ocular manifestations of psoriatic arthritis among denizens of the Amazon region of Para, Brazil, treated by the rheumatology service of Universidade do Estado do Pará. Methods: This cross-sectional study examined 23 psoriatic arthritis patients (median age 47.78 years, no sex predominance) diagnosed according to Caspar’s criteria. Disease activity was evaluated according to the Clinical Disease Activity Index for Psoriatic Arthritis. Ophthalmological examinations performed included visual acuity with distance correction, biomicroscopy, applanation tonometry, fundoscopy, Schirmer test I, tear breakup time, fluorescein staining, and lissamine green staining. Patients also completed The Ocular Surface Disease Index questionnaire. Results: The most common ophthalmic disorders were dry eye (60.9%), cataracts (56.5%), blepharitis (47.8%), keratitis (43.5%), meibomitis (30.4%), pterygium (26, 1%), and pinguecula (13%). More than half of all patients demonstrated recent onset (>5 years), the peripheral disease type, and severe symptoms according to Clinical Disease Activity Index for Psoriatic Arthritis. Conclusion: The ocular manifestations of psoriatic arthritis are varied and mainly affect the ocular surface. Regular ophthalmological follow-up is recommended for patients in the early stage with high disease activity.

https://doi.org/10.5935/0004-2749.20220086

12.

A promoção e proteção do aleitamento materno em meio a pandemia: relato de experiência
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Pereira, Raquel Ruzicki

; Fritzen, Liandra

; Bianchi, Gabriela

; Rosa, Eduarda Costa da

; Schiavoni, Laura Battistin

; Silveira, Paola Leticia da

; Oliveira, Natálie Araújo de

; Mendes, Ana Carolina

; Cristofoli, Bárbara Giordani

; Maahs, Marcia Angelica Peter

; Almeida, Sheila Tamanini de

; Berbert, Monalise Costa Batista

Revista Internacional em Língua Portuguesa

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Jun 2022, Volume 41 Páginas 125 - 132

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo O aleitamento materno é o primeiro alimento do bebê e a primeira forma de contato com a mãe, com a família e com a sociedade. Objetivo: Descrever ações de promoção do aleitamento materno desenvolvidas no atual cenário de distanciamento social. Metodologia: Trata-se de um relato de experiência de ações realizadas por um projeto de extensão no período de distanciamento social provocado pelo Coronavírus. Resultados: Foram produzidas 71 publicações sobre temas relevantes envolvidos com a amamentação e obtido um total de 734 seguidores no perfil do Instagram do projeto com alcance em torno de 1.191 pessoas. Discussão: Ressalta-se a importância de informações seguras sobre a prática de amamentar e acredita-se na importância de profissionais capacitados para incrementar a prevalência do aleitamento materno. Conclusão: Mesmo diante dos desafios frente à pandemia, o projeto conseguiu alcançar a sociedade além dos muros da universidade, bem como atingiu o objetivo de promover e proteger o aleitamento materno baseado em informações científicas.

Abstract Breastfeeding is the baby’s first food and the first form of contact with the mother, family, and society. Objective: to describe actions to promote breastfeeding developed in the current scenario of social distancing. Methodology: This is an experience report of the actions carried out by an extension project during the period of social distancing caused by the Coronavirus. Results: A total of 71 posts on relevant topics involved with breastfeeding were produced and a total of 734 followers were obtained on the project’s Instagram profile with a reach of around 1,191 people. Discussion: The importance of safe information about the practice of breastfeeding is emphasized, and the importance of trained professionals to increase the prevalence of breastfeeding is believed. Conclusion: even facing the challenges of the pandemic, the project managed to reach society beyond the walls of the university, and achieved its goal of promoting and protecting breastfeeding based on scientific information.

https://doi.org/10.31492/2184-2043.rilp2022.41/pp.125-132

13.

Ensino híbrido na formação em saúde: uma revisão sistemática
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Bezerra de Lima Danielle, Ana Carolina

; Moura dos Santos, Christine

; Lima de Almeida, Sabrina

; Lucena da Silva, Ellen

; Ferreira e Pereira, Emanuela Batista

Revista Cuidarte

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Abr 2022, Volume 13 Nº 1 elocation e8

Resumo: Es Pt En | Texto: Es Pt En | PDF: Es | PDF: Pt | PDF: En

Resumen Introducción: Ante la necesidad de reestructurar las instituciones de educación en salud a causa de la pandemia por COVID-19, se ha señalado a la educación híbrida como una alternativa para reorganizar las actividades educativas. El objetivo de este estudio es describir el desarrollo de la educación híbrida en la formación de los profesionales en el área de la salud. Materiales y métodos: Revisión sistemática de la literatura basada en las recomendaciones de los elementos de informes preferidos para revisiones sistemáticas y metaanálisis (PRISMA). La búsqueda se realizó por pares entre julio y septiembre de 2020 en cuatro bases de datos electrónicas. Los descriptores utilizados fueron “educación a distancia”, “educación superior”, “aprendizaje”, “salud”, “enfermería”, “medicina”, “odontología”, “fisioterapia” y “educación híbrida”. A su vez, los artículos seleccionados se clasificaron según su nivel de evidencia. Resultados: Se seleccionaron 49 artículos, entre los que se incluyeron estudios cuantitativos, cualitativos y de métodos mixtos. Se identificaron experiencias en el desarrollo de la educación híbrida en diferentes cursos de formación en el área de la salud. Se observó que la educación híbrida se implementó de acuerdo con el modelo de rotación, el modelo a la carta y el modelo Flex. Discusión: La enseñanza híbrida ha venido ganando cada vez más importancia en el escenario académico de la educación en salud. Se observó que, a partir de esta, el estudiante logra destacarse en su aprendizaje, ya que se convierte en el principal gestor de este proceso al aprender de forma activa mediante diversas herramientas educativas guiadas por el docente. Conclusiones: El éxito de la educación híbrida se puede relacionar con su carácter innovador, flexible, con buena relación costo-beneficio y la habilidad de convertir a los estudiantes en protagonistas de su proceso de enseñanza-aprendizaje, lo que influye en su propio rendimiento académico.

Resumo Introdução: A partir da necessidade de reestruturação das instituições de ensino em saúde devido à pandemia da COVID-19, o ensino híbrido vem se destacando como possibilidade de reorganização das atividades educativas. O objetivo: deste estudo foi escrever o desenvolvimento do ensino híbrido na formação de profissionais da área da saúde. Materiais e Métodos: Revisão sis- temática da literatura, baseada nas recomendações da Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). A pesquisa foi desenvolvida em pares, entre julho a setembro de 2020, em quatro bases de dados eletrôni- cas. Os descritores foram os termos “Educação a Distância”, “Educação Superior”, “Aprendizagem”, “Saúde”, “Enfermagem”, “Medicina”, “Odontologia” e “Fisiote- rapia” e “Ensino híbrido”. Os artigos foram classificados conforme seu Nível de Evidência. Resultados: 49 artigos foram selecionados, entre estudos quanti- tativos, qualitativos e de método misto. Foram encontradas experiências do desenvolvimento do ensino híbrido nos diferentes cursos de formação na área da saúde. Observou-se aplicação do ensino híbrido segundo o modelo de Ro- tação, modelo à la carte e o modelo Flex. Discussão: o ensino híbrido vem ganhando destaque cada vez maior no cenário da educação acadêmica em saúde. Foi visto que, a partir dele, o aluno destaca-se em sua aprendizagem, pois é o principal gerenciador deste processo, aprendendo ativamente por diversos ins- trumentos educativos a partir da condução do professor. Conclusões: O êxito do ensino híbrido pode estar relacionado ao seu caráter inovador, flexível, com boa relação custo-benefício e capaz de tornar os alunos protagonistas do seu processo de ensino-aprendizagem, influenciando no desempenho acadêmico dos alunos.

Abstract Introduction: Given the need to restructure healthcare education institutions due to the COVID-19 pandemic, hybrid education has been identified as an alternative to reorganize educational activities. The objective of this study is to describe hybrid education development in healthcare education. Materials and Methods: A systematic literature review was conducted based on the PRISMA (preferred reporting items for systematic reviews and meta-analyses) guideline. A peerreviewed search was conducted across four electronic databases between July and September 2020. Descriptors used were “distance education”, “learning”, “health”, “nursing”, “medicine”, “dentistry”, “physical therapy” and “hybrid education”. Selected articles were classified based on their level of evidence. Results: 49 articles were selected, including quantitative, qualitative and mixed methods studies. Experiences in the development of hybrid education in multiple healthcare courses were found. Hybrid education has been implemented based on the rotation model, a la carte model and Flex model. Discussion: Hybrid education has been gaining more and more importance in the academic scenario of healthcare education. Based on this, students manage to stand out in their learning process as they become the main agent of this process by actively learning using multiple education tools provided by their teachers. Conclusions: Successful hybrid education can be related to its innovative, flexible, cost-effective nature and the ability to turn students into key players in their teaching-learning process, which ends up influencing their own academic performance.

https://doi.org/10.15649/cuidarte.2051 105 downloads

14.

In vitro and ex vivo antiplasmodial activity of 1-(3-benzyloxy-4-methoxy-phenyl)-3-(3,4,5-trimethoxy-phenyl)-propan-1-one) against circulating strains of Plasmodium spp. in the state of Rondônia, Brazil 13benzyloxy4methoxyphenyl33,4,5trimethoxyphenylpropan1one 13benzyloxy4methoxyphenyl3345trimethoxyphenylpropan1one benzyloxymethoxyphenyltrimethoxyphenylpropanone 1 3 benzyloxy 4 methoxy phenyl 3,4,5 trimethoxy propan one 5 1-(3-benzyloxy-4-methoxy-phenyl)-3-(3,4,5-trimethoxy-phenyl)-propan-1-one spp Rondônia 13benzyloxy4methoxyphenyl33 5trimethoxyphenylpropan1one methoxyphenyl trimethoxyphenylpropan 345 3,4, benzyloxymethoxyphenyl 13benzyloxy4methoxyphenyl3 trimethoxyphenylpropanone 34 3,4 13benzyloxy4methoxyphenyl 3,
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Vicentini, Vanessa Margarida

; Nascimento, Welington da Silva Paula do

; Almeida, Marcinete Latorre

; Medeiros, Daniel Sol Sol de

; Santos, Ana Paula de Azevedo dos

; Costa, Joana D ‘Arc Neves

; Pereira, Dhélio Batista

; Tada, Mauro Shugiro

; Calderon, Leonardo de Azevedo

; Teles, Carolina Bioni Garcia

Brazilian Journal of Pharmaceutical Sciences

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2022, Volume 58 elocation e20453

Resumo: En | Texto: En | PDF: En

Abstract Malaria is a disease caused by Plasmodium spp. protozoa. The ability of Plasmodium to develop resistance to current antimalarial drugs makes the study of chemotherapeutic alternatives extremely important. This study aimed to evaluate the antimalarial activity of compound 3286938 (1-(3-benzyloxy-4-methoxy-phenyl)-3-(3,4,5-trimethoxy-phenyl)-propan-1-one), which presents in its structure a 3,4,5-trimethoxyphenyl group, in vitro, using the W2 strain of P. falciparum and against circulating strains of P. vivax and P. falciparum from the state of Rondônia. The compound 3286938 obtained an IC50 of 24.4 µM against the W2 strain of P. falciparum, and against the circulating strains, it presented a median (MD)=38.7 µM for P. vivax and MD=6.7 µM for P. falciparum. As for toxicity, 3286938 showed CC50 > 500 µM for VERO and HepG2 strains with a selectivity index greater than 12.9, a ratio calculated for P. falciparum and P. vivax regarding Vero and HepG2 cells. The compound was not considered hemolytic in in vitro assays, thus indicating the specificity of its antiplasmodial action. Based on the results presented, and considering the unprecedented character of the compound, it can be concluded that 3286938 was shown to be promising for complementary in vitro and in vivo studies aiming to produce effective antiplasmodial action. spp protozoa important 328693 13benzyloxy4methoxyphenyl33,4,5trimethoxyphenylpropan1one, 13benzyloxy4methoxyphenyl3345trimethoxyphenylpropan1one benzyloxymethoxyphenyltrimethoxyphenylpropanone 1 3 benzyloxy 4 methoxy phenyl 3,4,5 trimethoxy propan one , 5 (1-(3-benzyloxy-4-methoxy-phenyl)-3-(3,4,5-trimethoxy-phenyl)-propan-1-one) 3,4,5trimethoxyphenyl 345trimethoxyphenyl trimethoxyphenyl group W P Rondônia IC IC5 244 24 24. MD=38.7 MD387 MD =38.7 38 7 (MD)=38. MD67 6 MD=6. toxicity CC CC5 50 HepG 129 12 9 12.9 cells assays action 32869 13benzyloxy4methoxyphenyl33 5trimethoxyphenylpropan1one methoxyphenyl trimethoxyphenylpropan 13benzyloxy4methoxyphenyl33,4,5trimethoxyphenylpropan1one 345 3,4, (1-(3-benzyloxy-4-methoxy-phenyl)-3-(3,4,5-trimethoxy-phenyl)-propan-1-one 5trimethoxyphenyl 2 MD=38. MD38 387 =38. (MD)=38 MD6 MD=6 12. 3286 benzyloxymethoxyphenyl 13benzyloxy4methoxyphenyl3 trimethoxyphenylpropanone 34 3,4 MD=38 MD3 =38 (MD)=3 MD= 328 13benzyloxy4methoxyphenyl 3, MD=3 =3 (MD)= 32 = (MD) (MD

https://doi.org/10.1590/s2175-97902022e20453

15.

Booklet for knowledge and prevention of HIV mother-to-child transmission: a pilot study of a randomized clinical trial
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Lima, Ana Carolina Maria Araújo Chagas Costa

; Pinho, Sadrine Maria Eufrasino de

; Lima, Sabrina Alapenha Ferro Chaves Costa

; Chaves, Anne Fayma Lopes

; Vasconcelos, Camila Moreira Teixeira

; Oriá, Mônica Oliveira Batista

Revista da Escola de Enfermagem da USP

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2022, Volume 56 elocation e20210560

Resumo: Pt En Es | Texto: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO Objetivo: Testar efetividade de cartilha, em comparação ao atendimento habitual do serviço, no aumento do conhecimento de gestantes/puérperas que vivem com HIV, para prevenção da TV-HIV. Método: Piloto de ensaio clínico randomizado controlado, inicialmente com 104 gestantes que vivem com HIV, com amostra final de 45 mulheres. Realizado em três maternidades públicas de Fortaleza-CE, de janeiro/2017 a maio/2018. O grupo controle recebeu atendimento habitual do serviço e o grupo intervenção teve como aditivo acesso à cartilha. A pesquisa foi realizada em três fases: linha de base; avaliação 2, no pré-natal; e avaliação 3, no pós-parto. Resultados: Não houve diferença intergrupos na média da pontuação do conhecimento das mulheres (curto prazo p = 0,473; longo prazo p = 0,151). Porém, na análise intragrupo, a cartilha se mostrou efetiva para melhorar o conhecimento das gestantes do grupo intervenção, em curto prazo (p = 0,002) e longo prazo (p = 0,033). Conclusão Houve melhora do conhecimento dentro do grupo intervenção, ao longo do tempo, porém não foi evidenciada diferença quanto ao conhecimento das mulheres na análise intergrupos. Assim, a cartilha carece da realização de estudo mais amplo, a partir deste piloto, para comprovação de sua efetividade (ReBEC: UTN: U1111-1191-9954).

ABSTRACT Objective: To test the effectiveness of the booklet, compared to the usual service care, in the increase of the knowledge of pregnant/puerperal women living with HIV, for the prevention of HIV-VT. Method: Pilot study of a randomized controlled clinical trial, initially with 104 pregnant women living with HIV, with a final sample of 45 women. It was held in three public maternity hospitals in Fortaleza-CE, from January/2017 to May/2018. The control group received regular care from the service and the intervention group had access to the booklet as an additive. The research was carried out in three phases: baseline; evaluation 2, in prenatal care; and evaluation 3, in the postpartum period. Results: There was no intergroup difference in the women’s mean knowledge score (short-term p = 0.473; long-term p = 0.151). However, in the intragroup analysis, the booklet proved to be effective in improving the pregnant women’s knowledge in the intervention group, in the short term (p = 0.002) and long term (p = 0.033). Conclusion: There was an improvement in knowledge within the intervention group over time, but there was no difference in women’s knowledge in the intergroup analysis. Thus, based on this pilot, a broader study on the use of booklet is required to prove its effectiveness (ReBEC: UTN: U1111-1191-9954).

RESUMEN Objetivo: Testar la eficacia del cuardenillo, en comparación al servicio habitual, en el incremento del conocimiento de las mujeres embarazadas/puérperas que viven con el VIH, para la prevención del TV-VIH. Método: Piloto de un ensayo clínico controlado aleatorizado, inicialmente con 104 mujeres embarazadas que viven con el VIH, con una muestra final de 45 mujeres. Realizado en tres maternidades públicas de Fortaleza-CE, de enero/2017 a mayo/2018. El grupo control recibió atención regular del servicio y el grupo intervención tuvo acceso al cuadernillo como complemento. La investigación se llevó a cabo en tres etapas: línea de base; evaluación 2, en atención prenatal; y evaluación 3, en el puerperio. Resultados: No hubo diferencia entre grupos en la puntuación media de conocimiento de las mujeres (a corto plazo p = 0,473; a largo plazo p = 0,151). Sin embargo, en el análisis intragrupo, el cuardenillo se mostró eficaz en la mejora del conocimiento de las gestantes del grupo intervención, a corto plazo (p = 0,002) y a largo plazo (p = 0,033). Conclusión: Hubo una mejora en el conocimiento dentro del grupo de intervención con el tiempo, pero no hubo diferencia en el conocimiento de las mujeres en el análisis intergrupal. Por lo tanto, el cuadernillo necesita realizar un estudio más amplio, basado en este piloto, para probar su efectividad (ReBEC: UTN: U1111-1191-9954).

https://doi.org/10.1590/1980-220x-reeusp-2021-0560en

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Cód. do Índice	Elemento
ti	título do artigo
au	autor
kw	palavras-chave do artigo
subject	assunto (palavras do título, resumo e palavras-chave)
ab	resumo
ta	título abreviado da revista (ex. Cad. Saúde Pública)
journal_title	título completo da revista (ex. Cadernos de Saúde Pública)
la	código do idioma da publicação (ex. pt - Português, es - Espanhol)
type	tipo do documento
pid	identificador da publicação
publication_year	ano de publicação do artigo
sponsor	financiador
aff_country	código do país de afiliação do autor
aff_institution	instituição de afiliação do autor
volume	volume do artigo
issue	número do artigo
elocation	elocation
doi	número DOI
issn	ISSN da revista
in	código da coleção SciELO (ex. scl - Brasil, col - Colômbia)
use_license	código da licença de uso do artigo

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