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ABSTRACT Objective: To evaluate the focus of pediatricians’ gaze during the heel prick of neonates. Methods: Prospective study in which pediatricians wearing eye tracker glasses evaluated neonatal pain before/after a heel prtick. Pediatricians scored the pain they perceived in the neonate in a verbal analogue numerical scale (0=no pain; 10=maximum pain). The outcomes measured were number and time of visual fixations in upper face, lower face, and hands, in two 10-second periods, before (pre) and after the puncture (post). These outcomes were compared between the periods, and according to pediatricians’ pain perception: absent/mild (score: 0–5) and moderate/intense (score: 6–10). Results: 24 pediatricians (31 years old, 92% female) evaluated 24 neonates. The median score attributed to neonatal pain during the heel prick was 7.0 (Interquartile range: 5–8). Compared to pre-, in the post-periods, more pediatricians fixed their gaze on the lower face (63 vs. 92%; p=0.036) and the number of visual fixations was greater on the lower face (2.0 vs. 5.0; p=0.018). There was no difference in the number and time of visual fixations according to the intensity of pain. Conclusions: At bedside, pediatricians change their focus of attention on the neonatal face after a painful procedure, focusing mainly on the lower part of the face. Objective neonates Methods beforeafter prtick 0=no 0no 0 10maximum maximum 10 . pain) hands 10second second periods pre (pre post. post (post) perception absentmild absent mild (score 0–5 05 5 moderateintense moderate intense 6–10. 610 6–10 6 6–10) Results 2 31 (3 old 92 female 70 7 7. Interquartile range 5–8. 58 5–8 8 5–8) pre, , pre- postperiods, postperiods post-periods 63 (6 vs p=0.036 p0036 p 036 2.0 20 (2. 5.0 50 p=0.018. p0018 p=0.018 018 p=0.018) Conclusions bedside procedure 1 (post 0– 61 6–1 3 ( 9 5– p=0.03 p003 03 2. (2 5. p001 p=0.01 01 6– p=0.0 p00 p=0. p0 p=0 p=

RESUMO Objetivo: Avaliar o foco do olhar do pediatra durante a punção do calcanhar de neonatos. Métodos: Estudo prospectivo no qual pediatras, utilizando óculos de rastreamento visual, avaliaram a dor neonatal antes/depois de uma punção de calcanhar. Os pediatras pontuaram a dor de acordo com a sua percepção por meio de uma escala analógica verbal (0=sem dor; 10=dor máxima). Os desfechos analisados foram o número e o tempo das fixações visuais na face superior, face inferior e mãos, em dois períodos de 10 segundos, antes (PRÉ) e depois da punção (PÓS). Os resultados foram comparados entre os períodos e segundo a percepção da dor do pediatra: ausente/leve (escore: 0–5) e moderada/grave (escore: 6–10). Resultados: Vinte e quatro pediatras (31 anos, 92% sexo feminino) avaliaram 24 neonatos. A mediana do escore atribuído à dor do recém-nascido durante a punção do calcanhar foi 7,0 (intervalo interquartil: 5–8). Comparado ao período PRÉ, no período PÓS, o maior número de pediatras fixou o olhar na face inferior (63 vs. 92%; p=0,036) e o número de fixações visuais foi maior na face inferior (2,0 vs. 5,0; p=0,018). Não houve diferença no número e no tempo das fixações visuais de acordo com a intensidade da dor. Conclusões: À beira do leito, os pediatras mudam seu foco de atenção visual na face do recém-nascido após um procedimento doloroso, focando o olhar principalmente na parte inferior da face. Objetivo neonatos Métodos antesdepois 0=sem 0sem sem 0 10dor máxima. máxima . máxima) superior mãos 1 segundos PRÉ (PRÉ PÓS. PÓS (PÓS) ausenteleve ausente leve (escore 0–5 05 5 moderadagrave moderada grave 6–10. 610 6–10 6 6–10) Resultados 31 (3 anos 92 feminino 2 recémnascido recém nascido 70 7 7, intervalo interquartil 5–8. 58 5–8 8 5–8) 63 (6 vs p=0,036 p0036 p 036 2,0 20 (2, 5,0 50 p=0,018. p0018 p=0,018 018 p=0,018) Conclusões leito doloroso (PÓS 0– 61 6–1 3 ( 9 5– p=0,03 p003 03 2, (2 5, p001 p=0,01 01 6– p=0,0 p00 p=0, p0 p=0 p=

https://doi.org/10.1590/1984-0462/2024/42/2023089

Distal Radial Fractures with Scaphoid Fractures
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Nogueira, Caio Kzan Geyer

; Moraes, Vinícius Ynoe de

; Sarmento, Lucas Pereira

; Nakachima, Luís Renato

; Santos, João Baptista Gomes dos

; Belloti, João Carlos

Revista Brasileira de Ortopedia

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2024, Volume 59 Nº 2 Páginas 247 - 253

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

Abstract Objective This study evaluated the epidemiological data and functional outcomes from patients with concomitant distal radial and scaphoid fractures treated in a single center specialized in hand surgery. Functional outcomes analysis used validated instruments. Methods Patients diagnosed with distal radial and scaphoid fractures treated from January 2011 to December 2021 underwent assessments using the Disabilities of the Arm, Shoulder and Hand (DASH), Patient-Rated Wrist Evaluation (PRWE), Visual Analog Scale (VAS) for pain, goniometry, radiographic consolidation, and complications six months after surgery. Results The study included 23 patients, 73.9% men and 26.1% women. Most (56.5%) fractures occurred on the right side, and 43.5% happened on the left side. Treatment of most (56%) distal radial fractures used a locked volar plate. Functional assessment by PRWE resulted in a mean score of 35.9 points (range, 14 to 71 points), while DASH showed a mean score of 37.8 points (range, 12 to 78 points). The mean VAS was 2.33 during activities (range, 0.6 to 6.2). Conclusion Distal radial fractures associated with scaphoid fractures resulted from high-energy trauma, and most patients were males. There was a low rate of complications with surgical treatment, and the patients had satisfactory functional evolution with a low level of pain. surgery instruments 201 202 Arm DASH, , (DASH) PatientRated Patient Rated PRWE, (PRWE) (VAS pain goniometry consolidation 2 739 73 9 73.9 261 26 1 26.1 women 56.5% 565 56 5 (56.5% side 435 43 43.5 56% (56% plate 359 35 35. range, range (range 7 points, points) 378 37 8 37. points. . 233 33 2.3 06 0 6 0. 6.2. 62 6.2 6.2) highenergy high energy trauma males treatment 20 (DASH (PRWE 73. 26. 56.5 (56.5 4 43. (56 3 2. 6. 56. (56. (5 (

Resumo Objetivo Avaliar os resultados epidemiológicos e funcionais dos pacientes que apresentaram fraturas concomitantes do rádio distal e do escafoide e foram tratados em um único centro especializado em cirurgia da mão, através de instrumentos validados para analisar os desfechos funcionais desses pacientes. Métodos Foram avaliados os pacientes com diagnóstico de fratura do rádio distal e escafoide tratados de janeiro de 2011 até dezembro de 2021, através dos questionários Disabilities of the Arm, Shoulder and Hand (DASH), Patient Rated Wrist Evaluation (PRWE) e Escala Visual Analógica da dor (EVA); goniometria; consolidação radiográfica; complicações em seis meses de pós-operatório. Resultados Vinte e três pacientes foram incluídos no estudo, sendo 73,9% homens e 26,1% mulheres; 56,5% das fraturas ocorreram à direita e 43,5% à esquerda. A maioria das fraturas do rádio distal foi tratada com placa volar bloqueada, totalizando 56%. Na avaliação funcional pelo PRWE, obteve-se média de 35,9 pontos (variação de 14 a 71 pontos) e pelo DASH média de 37,8 pontos (variação de 12 a 78 pontos). A EVA apresentou uma média de 2,33 durante a atividade (variação de 0,6 a 6,2). Conclusão Verificou-se que as fraturas do rádio distal associadas a fraturas do escafoide foram causadas por traumas de alta energia, com o sexo masculino mais acometido. Houve baixo índice de complicações com tratamento cirúrgico e os pacientes tiveram evolução funcional satisfatória, com baixo índice de dor. mão 201 2021 Arm DASH, , (DASH) PRWE (PRWE (EVA) goniometria radiográfica pósoperatório. pósoperatório pós operatório. operatório pós-operatório estudo 739 73 9 73,9 261 26 1 26,1 mulheres 565 56 5 56,5 435 43 43,5 esquerda bloqueada 56% obtevese obteve se 359 35 35, variação 7 378 37 8 37, pontos. . 233 2 33 2,3 06 0 6 0, 6,2. 62 6,2 6,2) Verificouse Verificou energia acometido satisfatória 20 202 (DASH (EVA 73, 26, 56, 4 43, 3 23 2, 6,

https://doi.org/10.1055/s-0044-1785464

Relationship between early age at menarche, older age at menopause and subtypes of breast cancer: a scoping review menarche cancer
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Lopes, Lucas Casagrande Passoni

; Medeiros, Gabriel Araújo

; Gualberto, Igor José Nogueira

; Gut, Thales Baptista

; Ferrazini, Rafael Vasconcelos Silva

; Negrato, Carlos Antonio

Revista Brasileira de Ginecologia e Obstetrícia

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2024, Volume 46 elocation e-rbgo50

Resumo: En | Texto: En | PDF: En

Abstract Objective To determine the relationship between early age at menarche, late age at menopause with specific subtypes of breast cancer (BC). Methods A literature search was conducted in Embase, Lilacs, PubMed, Scopus, and Scielo databases, following the Joanna Briggs Institute scoping review protocol and answering the question “How early age at menarche or late age at menopause are related to different breast cancer subtypes?”. Results A number of 4,003 studies were identified, of which 17 were selected. Most of the included articles found a clear relationship between early menarche, late menopause and some subtypes of BC, mainly, PR+, ER+, luminal, and HER-2 tumors. However, some studies have found a contradictory relationship and one study didn’t find any relationship between them. Conclusion A relationship between early age at menarche and advanced age at menopause was observed with some subtypes of breast cancer, since other factors must be considered in its understanding. BC. BC . (BC) Embase Lilacs PubMed Scopus databases How subtypes. subtypes?” 4003 4 003 4,00 identified 1 selected mainly PR PR+ ER ER+ luminal HER2 HER 2 HER- tumors However didnt didn t them understanding (BC subtypes? 400 00 4,0 40 0 4,

https://doi.org/10.61622/rbgo/2024rbgo50

Safety of CoronaVac and ChAdOx1 vaccines against SARS-CoV-2 in patients with rheumatoid arthritis: data from the Brazilian multicentric study safer ChAdOx SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- arthritis SARS-CoV
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Cruz, Vitor Alves

; Guimarães, Camila

; Rêgo, Jozelia

; Machado, Ketty Lysie Libardi Lira

; Miyamoto, Samira Tatiyama

; Burian, Ana Paula Neves

; Dias, Laiza Hombre

; Pretti, Flavia Zon

; Batista, Danielle Cristina Filgueira Alves

; Mill, José Geraldo

; Oliveira, Yasmin Gurtler Pinheiro de

; Gadelha, Carolina Strauss Estevez

; Gouveia, Maria da Penha Gomes

; Moulin, Anna Carolina Simões

; Souza, Bárbara Oliveira

; Aguiar, Laura Gonçalves Rodrigues

; Vieira, Gabriel Smith Sobral

; Grillo, Luiza Lorenzoni

; Lima, Marina Deorce de

; Pasti, Laís Pizzol

; Surlo, Heitor Filipe

; Faé, Filipe

; Moulaz, Isac Ribeiro

; Macabú, Mariana de Oliveira

; Ribeiro, Priscila Dias Cardoso

; Magalhães, Vanessa de Oliveira

; Aguiar, Mariana Freitas de

; Biegelmeyer, Erika

; Peixoto;, Flávia Maria Matos Melo Campos

; Kayser, Cristiane

; Souza, Alexandre Wagner Silva de

; Castro, Charlles Heldan de Moura

; Ribeiro, Sandra Lúcia Euzébio

; Telles, Camila Maria Paiva França

; Bühring, Juliana

; Lima, Raquel Lima de

; Santos, Sérgio Henrique Oliveira Dos

; Dias, Samuel Elias Basualto

; Melo, Natália Seixas de

; Sanches, Rosely Holanda da Silva

; Boechat, Antonio Luiz

; Sartori, Natália Sarzi

; Hax, Vanessa

; Dória, Lucas Denardi

; Rezende, Rodrigo Poubel Vieira de

; Baptista, Katia Lino

; Fortes, Natália Rodrigues Querido

; Melo, Ana Karla Guedes de

; Melo, Tâmara Santos

; Vieira, Rejane Maria Rodrigues de Abreu

; Vieira, Adah Sophia Rodrigues

; Kakehasi, Adriana Maria

; Tavares, Anna Carolina Faria Moreira Gomes

; Landa, Aline Teixeira de

; Costa, Pollyana Vitoria Thomaz da

; Azevedo, Valderilio Feijó

; Martins-Filho, Olindo Assis

; Peruhype-Magalhães, Vanessa

; Pinheiro, Marcelo de Medeiros

; Monticielo, Odirlei André

; Reis-neto, Edgard Torres Dos

; Ferreira, Gilda Aparecida

; Souza, Viviane Angelina de

; Teixeira-Carvalho, Andréa

; Xavier, Ricardo Machado

; Sato, Emilia Inoue

; Valim, Valeria

; Pileggi, Gecilmara Salviato

; Silva, Nilzio Antonio da

Advances in Rheumatology

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2024, Volume 64 elocation 58

Resumo: En | Texto: En | PDF: En

Abstract Background Patients with immune-mediated rheumatic diseases (IMRDs) have been prioritized for COVID-19 vaccination to mitigate the infection severity risks. Patients with rheumatoid arthritis (RA) are at a high risk of severe COVID-19 outcomes, especially those under immunosuppression or with associated comorbidities. However, few studies have assessed the safety of the COVID-19 vaccine in patients with RA. Objective To evaluate the safety of vaccines against SARS-CoV-2 in patients with RA. Methods This data are from the study “Safety and Efficacy on COVID-19 Vaccine in Rheumatic Diseases,” a Brazilian multicentric prospective phase IV study to evaluate COVID-19 vaccine in IMRDs in Brazil. Adverse events (AEs) in patients with RA of all centers were assessed after two doses of ChAdOx1 (Oxford/AstraZeneca) or CoronaVac (Sinovac/Butantan). Stratification of postvaccination AEs was performed using a diary, filled out daily and returned at the end of 28 days for each dose. Results A total of 188 patients with RA were include, 90% female. CoronaVac was used in 109 patients and ChAdOx1 in 79. Only mild AEs were observed, mainly after the first dose. The most common AEs after the first dose were pain at the injection (46,7%), headache (39,4%), arthralgia (39,4%), myalgia (30,5%) and fatigue (26,6%), and ChAdOx1 had a higher frequency of pain at the injection (66% vs 32 %, p < 0.001) arthralgia (62% vs 22%, p < 0.001) and myalgia (45% vs 20%, p < 0.001) compared to CoronaVac. The more common AEs after the second dose were pain at the injection (37%), arthralgia (31%), myalgia (23%), headache (21%) and fatigue (18%). Arthralgia (41,4% vs 25%, p = 0.02) and pain at injection (51,4% vs 27%, p = 0.001) were more common with ChAdOx1. No serious AEs were related. With Regard to RA activity level, no significant difference was observed between the three time periods for both COVID-19 vaccines. Conclusion In the comparison between the two immunizers in patients with RA, local reactions and musculoskeletal symptoms were more frequent with ChAdOx1 than with CoronaVac, especially after the first dose. In summary, the AE occurred mainly after the first dose, and were mild, like previous data from others immunizing agents in patients with rheumatoid arthritis. Vaccination did not worsen the degree of disease activity. immunemediated immune mediated (IMRDs COVID19 COVID 19 COVID-1 risks (RA outcomes comorbidities However SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- Safety Diseases, Diseases Brazil (AEs ChAdOx Oxford/AstraZeneca OxfordAstraZeneca Oxford AstraZeneca (Oxford/AstraZeneca Sinovac/Butantan. SinovacButantan Sinovac/Butantan . Sinovac Butantan (Sinovac/Butantan) diary 18 include 90 female 10 79 46,7%, 467 46,7% , 46 7 (46,7%) 39,4%, 394 39,4% 39 4 (39,4%) 30,5% 305 30 5 (30,5% 26,6%, 266 26,6% 26 6 (26,6%) 66% 66 (66 3 % 0.001 0001 0 001 62% 62 (62 22 22% 45% 45 (45 20 20% 37%, 37 37% (37%) 31%, 31 31% (31%) 23%, 23 23% (23%) 21% 21 (21% 18%. 18% (18%) 41,4% 414 41 (41,4 25 25% 0.02 002 02 51,4% 514 51 (51,4 27 27% related level summary COVID1 1 COVID- SARS-CoV (Sinovac/Butantan 9 46,7 (46,7% 39,4 (39,4% 30,5 (30,5 26,6 (26,6% (6 0.00 000 00 (4 (37% (31% (23% (21 (18% 41,4 (41, 0.0 51,4 (51, 46, (46,7 39, (39,4 30, (30, 26, (26,6 ( (37 (31 (23 (2 (18 41, (41 0. 51, (51 (46, (39, (30 (26, (3 (1 (5 (46 (39 (26

https://doi.org/10.1186/s42358-024-00397-5

Determination of the critical threshold for the occurrence of fires in the Parque Nacional de Brasília (Brazil) through temporal analysis using spectral índices Brazil (Brazil
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Silva, Lucas Inácio da

; Baptista, Gustavo Macedo de Mello

Sociedade & Natureza

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2023, Volume 35 elocation e67446

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

Abstract The Brazilian Savannah is one of the largest biomes in Brazil. Unfortunately, human pressure is aggravating the degradation processes of the biome and, together with the drought processes, fire events are a major concern. Monitoring tools must be designed, especially those involving the concepts of remote sensing, in anticipation of the fire phenomenon, mitigating the devastating effects. Therefore, the present research aims to determine the critical threshold for the occurrence of fires through the diagnosis of the conditions of greenness, humidity and senescence of the vegetation using the temporal analysis of Sentinel-2 images in the Parque Nacional de Brasília. Therefore, it is necessary to quantitatively determine each condition through the analysis of past events, determining the criticality threshold that conditions the region to present conditions that favor the onset of a fire, as well as the construction of an algorithm, in the Google Earth Engine. The study area is the Parque Nacional de Brasília, with the image data collection Harmonized Sentinel-2 MSI: MultiSpectral Instrument, Level-1C inside the Google Earth Engine. The algorithm aims to build a masking system to remove materials from the scenes, as well as the calculation of the NDVI, NDII, PSRI and dNBR indices, extracting the data through the mask of burned pixels. It was possible to identify six periods of fire occurrence, the data extraction allowed the statistical determination of the threshold, which was 0,580 for the NDVI, 0,015 for the NDII and 0,150 for the PSRI. Brazil Unfortunately concern designed sensing phenomenon effects Therefore greenness Sentinel2 Sentinel 2 Sentinel- Brasília Engine MSI Instrument Level1C LevelC Level 1C C scenes NDVI indices pixels 0580 0 580 0,58 0015 015 0,01 0150 150 0,15 058 58 0,5 001 01 0,0 15 0,1 05 5 0, 00 1

Resumo O Cerrado brasileiro é um dos maiores biomas do Brasil. Infelizmente a pressão antrópica está agravando os processos de degradação do bioma e juntamente com os processos de estiagem, os eventos de fogo surgem como grande fator de preocupação. Devem ser concebidos ferramentas de monitoramento, principalmente os que envolvem os conceitos de sensoriamento remoto, antepondo-se ao fenômeno de fogo, mitigando os efeitos devastadores. Sendo assim, a presente pesquisa tem como objetivo a determinação do limiar crítico à ocorrência de incêndios por meio do diagnóstico das condições de verdor, umidade e senescência da vegetação utilizando da análise temporal de imagens “Sentinel-2” no Parque Nacional de Brasília, para isso, faz-se necessário a determinação quantitativa de cada condição por meio da análise de eventos passados, determinando o limiar de criticidade que condicione a região apresentar condições que favoreçam o início de um incêndio bem como a construção de um algoritmo, no “Google Earth Engine”. Á área de estudo é o Parque Nacional de Brasília, com o acervo de dados de imagens “Harmonized Sentinel-2 MSI: MultiSpectral Instrument, Level-1C” dentro do “Google Earth Engine”. O algoritmo visa construir um sistema de máscaras para remover materiais das cenas, bem como o cálculo dos índices NDVI, NDII, PSRI e dNBR, extraindo os dados por meio da máscara de pixels queimados. Foi possível identificar seis períodos de ocorrência de fogo, a extração de dados permitiu a determinação estatística do limiar, sendo esse 0,580 para o NDVI, 0,015 para o NDII e 0.150 para o PSRI. Brasil estiagem preocupação monitoramento remoto antepondose antepondo se devastadores assim verdor Sentinel2 Sentinel 2 “Sentinel-2 Brasília isso fazse faz passados Google Engine. Engine . Engine” Harmonized Sentinel- MSI Instrument Level1C LevelC Level 1C C Level-1C cenas NDVI dNBR queimados 0580 0 580 0,58 0015 015 0,01 0150 150 0.15 “Sentinel- 058 58 0,5 001 01 0,0 15 0.1 “Sentinel 05 5 0, 00 1 0.

https://doi.org/10.14393/sn-v35-2023-67446x

Effects of Physical Exercise on Lipid and Inflammatory Profile of Women Using Combined Oral Contraceptive: A Cross-Over Study
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Gomes, Vinícius Afonso

; Sacramento, Marvyn de Santana do

; Cecilia, Lucas Mendes Santa

; Jesus, Daniela Santos de

; Barbosa, Juliane Santos

; Almeida, Fernanda Oliveira Baptista de

; Oliveira, Elaine Carvalho de

; Petto, Jefferson

International Journal of Cardiovascular Sciences

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Ago 2022, Volume 35 Nº 4 Páginas 500 - 510

Resumo: En | Texto: En | PDF: En

Abstract Background: The use of combined oral contraceptives (COC) is a risk factor for atherosclerotic disease, and physical exercise can minimize this condition. Objective: To verify if high intensity interval training (HIIT) promotes changes in the lipid and inflammatory profile of women using COC. Methods: Sequential crossover study with women aged 20-30 years, classified as irregularly active by the international physical activity questionnaire (IPAQ), when using COC. A physical-clinical assessment was performed with anthropometric measurements, VO2max, and analysis of lipid and inflammatory profile. Participants were divided into 2 groups: the initial intervention group (GII), which began practicing HIIT for 2 months, and the posterior intervention group (GIP), which remained inactive for the same period. The GII and GIP would then alternate their conditions. The collected data was divided into: Initial moment (IM), post-exercise moment (PEM) and post-inactivity (PIM). The statistical analyses were performed using the Statistical Package for the Social Sciences, adopting a significance level of p <0.05 . Results: Twelve women were evaluated. After crossing the GII and GIP data, there was a difference in the C-reactive protein values between the IM of 4 (1.6-6.3 mg/dL) vs. PEM 2 (1.5-5 mg/dL); as well as between the PEM vs. the PIM= 4 (1.5-5.8 mg/dL), with a p -value = 0.04 in the comparisons. There was no change between the “moments” of the lipid profile, although it was possible to notice a reduction in resting HR and an increase in indirect VO2max. Conclusion: The HIIT program was able to reduce the inflammatory profile, but it did not alter the lipid profile of irregularly active women using COC.

https://doi.org/10.36660/ijcs.20200399

COVID-19 findings in chest computed tomography
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Calvi, Camila

; Ferreira, Fernanda Filetti

; Lyrio, Lucas

; Baptista, Rodrigo de Melo

; Zanoni, Barbara Binda

; Junger, Ynara Olivier

; Barros, Wagner Haese

; Volpato, Ricardo

; Mule Júnior, Libório

; Rosa Júnior, Marcos

Revista da Associação Médica Brasileira

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Out 2021, Volume 67 Nº 10 Páginas 1409 - 1414

Resumo: En | Texto: En | PDF: En

SUMMARY OBJECTIVE: The aim of this study was to describe chest computed tomography image findings in patients with COVID-19. METHODS: The chest computed tomography scans of 453 hospitalized patients with confirmed COVID-19 were collected at two tertiary care Brazilian hospitals. Demographics and clinical data were extracted from the electronic record medical system. RESULTS: The main chest computed tomography findings were ground-glass opacities (92.5%), consolidation (79.2%), crazy-paving pattern (23.9%), parenchymal bands (50%), septal thickening (43.5%), and inverted halo sign (3.5%). Of the 453 hospitalized patients, 136 (30%) died. In this group, ground-glass opacities (94.1%), consolidation (89.7%), septal thickening (58.1%), crazy-paving pattern (52.2%), and parenchymal bands (39.7%) were the most common imaging findings. CONCLUSIONS: In a dynamic disease with a broad clinical spectrum such as COVID-19, radiologists can cooperate in a better patient management. On wisely indicated chest computed tomography scans, the fast identification of poor prognosis findings could advise patient management through hospital care facilities and clinical team decisions.

https://doi.org/10.1590/1806-9282.20210414

Endovascular management of transplant renal artery stenosis: early and mid-term results
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Pinto, Vanda

; Lopez, Noélia

; Cardoso, Ana

; Henriques, Mickael

; Silva, Emanuel

; Silvestre, Luís

; Baptista, Lucas

; Guerra, José

; Pedro, Luís Mendes

; Ministro, Augusto

Angiologia e Cirurgia Vascular

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Set 2021, Volume 17 Nº 3 Páginas 238 - 244

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo Objetivos: A disfunção de enxerto renal e agravamento de hipertensão nos pacientes transplantado renais podem ser manifestações de hipoperfusão do enxerto devido a estenose de artéria de transplante renal (EATR) ou estenose da artéria ilíaca proximal à anastomose do enxerto (pseudo-EATR). O tratamento endovascular de EATR é cada vez mais frequente para manter a função do enxerto. Com este estudo, pretendemos avaliar o impacto do tratamento endovascular de EATR na função renal a curto e médio prazo. Materiais e métodos: Este é um estudo observacional, retrospetivo, monocêntrico que inclui todos os pacientes transplantados renais adultos submetidos a tratamento endovascular de EATR entre Setembro de 2017 e Junho de 2020. A função renal foi monitorizada através da medição da creatinina sérica (sCr). Resultados: Treze pacientes foram incluídos (53.8% do sexo feminino), com idade média de 57 (21-70) anos. Onze pacientes (84.6%) desenvolveram disfunção de enxerto. Dez pacientes (76.9%) foram submetidos a angioplastia transluminal e colocação de stent na artéria renal do enxerto e três (23.1%) da artéria ilíaca dadora. A maior parte dos casos (69.2%) foram tratados durante o primeiro ano pós transplante. A taxa de sucesso técnico foi de 100%, sem mortalidade periprocedimento. A taxa de morbilidade aos 30 dias foi de 15.4%. O tempo médio de seguimento foi de 20.2 (1.3 - 36.3) meses. Um doente morreu durante o seguimento e outro sofreu agravamento de disfunção do enxerto com necessidade de hemodiálise e nefrectomia. A redução na sCr foi estatisticamente significativa no primeiro mês pós-intervenção, comparado aos valores pré-intervenção, mas a sCr continuou aumentada quando comparada aos níveis basais (pré-diagnóstico de EATR). Conlusão: A maioria dos pacientes (12/13) melhorou ou estabilizou a função renal após a intervenção em relação ao período pré-intervenção, mostrando a eficácia do procedimento. No entanto, a maior parte dos doentes não retornou aos valores basais de sCr, corroborando a importância da revascularização precoce do enxerto. O atraso no diagnóstico de EATR pode comprometer o benefício da revascularização e impedir a recuperação total da função renal.

Abstract Objective: Renal graft dysfunction or worsened hypertension in renal transplanted patients may be a manifestation of graft hypoperfusion due to transplant renal artery stenosis (TRAS) or stenosis of iliac arteries proximal to renal transplant (pseudo-TRAS). Endovascular management of TRAS has been increasingly used to preserve renal graft function. With this study, we aim to evaluate the impact of endovascular treatment of TRAS on renal function in the short to medium term. Material and methods: This is an observational, retrospective, single-center study that included all adult renal transplant patients who underwent endovascular intervention on TRAS between September 2017 and June 2020. Renal graft function was monitored by serum Creatinine (sCr) levels. Results: Thirteen patients were included (53.8% female), with a median age of 57 (21-70) years. Eleven patients (84.6%) presented with graft dysfunction. Ten subjects (76.9%) underwent transluminal angioplasty and stenting of renal artery and three (23,1%) of donor iliac arteries. Most cases (69.2%) were interventioned in the first-year post-transplant. Overall technical success was 100%, with no periprocedural deaths. Overall 30-day morbidity was 15.4%. Median follow-up time was 20.2 (1,3 - 36,3) months. One patient died during follow up and other worsened graft dysfunction, requiring hemodialysis and nephrectomy. Reduction in sCr levels was statistically significant in the first postoperative month, compared to preoperative values, but sCR levels were still increased when compared to baseline levels (pre-TRAS diagnosis). Conclusions: The majority (12/13) of patients showed improvement or stabilization of renal graft function compared to the preoperative period, during the follow-up period, supporting the procedure’s safety. Despite this, most patients did not recover baseline sCr levels, reinforcing the importance of prompt graft revascularization. Delayed diagnosis of TRAS may compromise the benefit of revascularization and prevent full recovery of renal function.

https://doi.org/10.48750/acv.389 42 downloads

Hematoma Intramural da Artéria Pulmonar Associado a Dissecção Aórtica Aguda
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Farias, Lucas de Pádua Gomes de

; Favaretto, Ana Cristina

; Baptista, Luciana de Pádua Silva

; Teles, Gustavo Borges da Silva

Arquivos Brasileiros de Cardiologia

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Jun 2021, Volume 116 Nº 6 Páginas 1169 - 1171

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

https://doi.org/10.36660/abc.20200775 73 downloads

10.

Diagnosis Accuracy of Baptista Depression Scale: Adult and Screening Versions
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Gonçalves, André Pereira

; Baptista, Makilim Nunes

; Villemor-Amaral, Anna Elisa de

; Carvalho, Lucas de Francisco

Psicologia: Teoria e Pesquisa

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2021, Volume 37 elocation e37449

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo O objetivo da presente investigação foi verificar a acurácia diagnóstica da Escala Baptista de Depressão adulto e triagem (EBADEP-A e EBADEP- triagem) para discriminação de pessoas com episódio depressivo maior (EDM) e/ou transtorno depressivo maior (TDM), e comparar suas capacidades discriminativas. Participaram 187 pessoas, 52 pacientes e 135 do grupo não clínico. Os resultados indicaram sensibilidade igual a 0,92 e especificidade igual a 0,88 para a EBADEP-A (ponto de corte igual a 54), e 0,96 e 0,82, respectivamente, para a EBADEP-triagem (ponto de corte igual a 17). Os achados sugerem equivalência entre as duas versões da EBADEP para discriminação de pessoas com EDM e/ou TDM. Os resultados indicam que as duas versões podem fornecer um indicativo diagnóstico correto para EDM e TDM.

Abstract This study aimed to investigate the diagnostic accuracy of the Baptista Depression Scale adult and screening versions (EBADEP-A and EBADEP-screening) for discrimination of people with a major depressive episode (MDE) or major depressive disorder (MDD) and to compare discriminative capacities. Participants were 187 people, 52 patients, and 135 non-clinical individuals. Results indicated sensitivity equal to 0.92 and specificity equal to 0.88 for EBADEP-A (cut-off = 54), and 0.96 and 0.82, respectively, for EBADEP-screening (cut-off = 17). Findings suggest equivalence between the two versions of EBADEP to discriminate people with MDE or MDD. Results indicate that the two versions can provide a correct diagnostic indicative for MDE and MDD.

https://doi.org/10.1590/0102.3772e37449 59 downloads

11.

Transplante renal em dador vivo - um caso vascular complexo
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Pinto, Vanda

; Ministro, Augusto

; Silvestre, Luís

; Pedro, Luís Mendes

; Lopez, Noélia

; Guerra, José

; Baptista, Lucas

Angiologia e Cirurgia Vascular

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Set 2020, Volume 16 Nº 3 Páginas 181 - 185

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Introdução: A presença de múltiplos vasos renais é frequente na população geral e, quando presente num dador, aumenta a complexidade da cirurgia de transplantação renal, aumentando o risco de complicações. Embora a transplantação de enxertos de dador cadáver com estas características seja aceite, o mesmo procedimento em dador vivo permanece controverso. O objetivo deste trabalho é apresentar o caso de uma cirurgia de transplantação de dador vivo com anatomia vascular complexa - duas artérias e duas veias renais Caso Clínico: Mulher de 42 anos, com doença renal crónica terminal (DRCT) por nefropatia IgA, em programa regular de hemodiálise há 9 meses, avaliada em mais de um centro para transplantação renal de dador vivo e recusada pela complexidade da anatomia vascular do par dador - rim direito com duas artérias e duas veias renais curtas No nosso centro, onde a cirurgia vascular integra a equipa multidisciplinar de transplantação renal, foi aceite o transplante considerando-se tecnicamente exequível a reconstrução vascular ex-vivo do enxerto (back table) Na reconstrução arterial foi realizada anastomose látero-lateral das duas artérias renais. A reconstrução venosa incluiu o alongamento das veias renais com veia safena interna (VSI) da recetora e a sua posterior anastomose em “cano de espingarda”. O rim foi implantado na fossa ilíaca direita da recetora Verificou-se diurese imediata após desclampagem, com descida rápida dos valores de creatinina para o normal e com alta ao 16.º dia de pós-operatório Conclusão: A escassez de órgãos é um importante fator limitante à transplantação renal. A inclusão de dadores com múltiplos vasos renais tem demonstrado bons resultados e pode aumentar a disponibilidade de órgãos. A integração de um cirurgião vascular experiente na equipa multidisciplinar de transplantação renal permite a realização de reconstruções arteriais e venosas complexas em enxertos com anatomia vascular menos favorável

Introduction: The presence of multiple renal vessels is frequent in the general population and, when present in a donor, increases the complexity of renal transplantation surgery, increasing the risk of complications. Although transplantation of cadaver donor grafts with these characteristics is accepted, the same procedure in living donor remains controversial. The objective of this work is to present the case of a living donor renal transplant surgery with complex vascular anatomy - two arteries and two renal veins Clinical case: 42-year-old woman with end stage renal disease due to IgA nephropathy, on regular hemodialysis program for 9 months, evaluated in more than one center for living donor renal transplantation and rejected by the complexity of the vascular anatomy of the donor - right kidney with two arteries and two short renal veins. In our center, where vascular surgery integrates the multidisciplinary team of renal transplantation, the transplant was accepted considering that the ex-vivo vascular reconstruction of the graft (back table) was technically feasible Arterial reconstruction was performed on a lateral-lateral anastomosis of the two renal arteries. Venous reconstruction included the stretching of the renal veins with the great saphenous vein of the recipient and its posterior lateral-lateral anastomosis. The kidney was implanted in the recipient's right iliac fossa Immediate diuresis after dislodging was observed, with a rapid decrease in creatinine values to normal and discharged on the 16th postoperative day Conclusion: Organ shortage is an important limiting factor for renal transplantation. Inclusion of donors with multiple renal vessels has shown good results and may increase organ availability. The integration of an experienced vascular surgeon in the multidisciplinary team of renal transplantation allows the accomplishment of complex arterial and venous reconstructions in grafts with less favorable vascular anatomy

331 downloads

12.

Diagnostic accuracy of preoperative magnetic resonance imaging for detecting subscapularis tendon tears: a diagnostic test study
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Ramadan, Lucas Busnardo

; Baptista, Eduardo

; Souza, Felipe Ferreira de

; Gracitelli, Mauro Emilio Conforto

; Assunção, Jorge Henrique

; Andrade-Silva, Fernando Brandao

; Ferreira-Neto, Arnaldo Amado

; Malavolta, Eduardo Angeli

Sao Paulo Medical Journal

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Ago 2020, Volume 138 Nº 4 Páginas 310 - 316

Resumo: En | Texto: En | PDF: En

ABSTRACT BACKGROUND: The accuracy of magnetic resonance imaging (MRI) for making the diagnosis of subscapularis tears presents wide variation in the literature and there are few prospective studies. OBJECTIVE: To compare the findings from MRI and arthroscopy for diagnosing subscapularis tears. DESIGN AND SETTING: Diagnostic test study performed in a tertiary care hospital. METHODS: We included patients who underwent arthroscopic rotator cuff repair and who had firstly undergone high magnetic field MRI without contrast. The images were independently evaluated by a shoulder surgeon and two musculoskeletal radiologists. Sensitivity, specificity, positive and negative predictive values, accuracy and inter and intra-observer agreement were calculated. RESULTS: MRIs on 200 shoulders were evaluated. The incidence of subscapularis tears was 69.5% (41.5% partial and 28.0% full-thickness). The inter and intra-observer agreement was moderate for detection of subscapularis tears. The shoulder surgeon presented sensitivity of 51.1% to 59.0% and specificity of 91.7% to 94.4%. The radiologists showed sensitivity of 83.5% to 87.1% and specificity of 41% to 45.9%. Accuracy ranged from 60.5% to 73.0%. CONCLUSION: The 1.5-T MRIs without contrast showed mean sensitivity of 70.2% and mean specificity of 61.9% for detection of subscapularis tears. Sensitivity was higher for the musculoskeletal radiologists, while specificity was higher for the shoulder surgeon. The mean accuracy was 67.6%, i.e. lower than that of rotator cuff tears overall.

https://doi.org/10.1590/1516-3180.2020.014605062020 447 downloads

13.

Increased levels of reactive oxygen species in platelets and platelet-derived microparticles and the risk of respiratory failure in HIV/AIDS patients
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Gama, Wellington Mota

; Oliveira, Lucas Barbosa

; Chaves, Yury Oliveira

; Ribeiro, Flavio

; Almeida, Taynná Vernalha Rocha

; Baptista, Barbara Jose Antunes

; Santana, Monique Freire

; Ferreira, Luis Carlos

; Lacerda, Marcus Vinicius Guimaraes

; Nogueira, Paulo Afonso

Memórias do Instituto Oswaldo Cruz

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2020, Volume 115 elocation e200082

Resumo: En | Texto: En | PDF: En

Respiratory failure (RF) is the main cause of hospital admission in HIV/AIDS patients. This study assessed comorbidities and laboratory parameters in HIV/AIDS inpatients with RF (N = 58) in relation to those without RF (N = 36). Tuberculosis showed a huge relative risk and platelet counts were slightly higher in HIV/AIDS inpatients with RF. A flow cytometry assay for reactive oxygen species (ROS) showed lower levels in platelets of these patients in relation to the healthy subjects. However, when stimulated with adrenaline, ROS levels increased in platelets and platelet-derived microparticles of HIV/AIDS inpatients, which may increase the risk of RF during HIV and tuberculosis (HIV-TB) coinfection.

https://doi.org/10.1590/0074-02760200082 503 downloads

14.

Determination of maximum zinc recovery of Vazante mine ore by flotation process
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Bechir, Jorge Lucas Carvalho

; Baptista, José Renato

; Souza, Adelson Dias de

; Martins, Eder

REM - International Engineering Journal

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Jun 2019, Volume 72 Nº 2 Páginas 315 - 320

Resumo: En | Texto: En | PDF: En

Abstract Nowadays, Nexa Resources (ex-Votorantim Metais) operates two zinc mines in Brazil, represented by the Vazante unit in Vazante - MG and the Morro Agudo unit in Paracatu - MG. The present study was carried out at the Vazante unit, where zinc concentrate is produced from a silicate ore called Willemite (Zn2SiO4) through froth flotation processes. The two main objectives of the study were the determination of the maximum zinc recovery that could be obtained in flotation bench tests with specific controlled conditions and the mineral characterization of the tailings generated, using a SEM/EDS (scanning electron microscope with energy dispersive x-ray spectroscopy) with MLA (mineral liberation analyzer). The flotation results showed a maximum recovery of 91.91 % with 1.68 % of zinc in the tailings after an eleven-minute flotation. Considering the mean results of all the tests, the maximum zinc recovery obtained was 91.07 % with 1.75 % zinc grade in the tailings. Mineral characterization analysis showed that zinc minerals besides Willemite, such as Gahnite and Franklinite are present in the zinc tailings. In addition, the analysis demonstrated that the Willemite present in the tailings is very fine (80 % < 0.015 mm) and well liberated. With no liberation problems, it was concluded that the main reason responsible for preventing zinc recovery to increase even more along the flotation tests was the presence of the extremely fine Willemite minerals. The test results showed that, to increase zinc recovery, two main processes needed to be considered. The grinding process, that will need to be improved and carefully revised to reduce Willemite fine grain size generation; and the flotation process, regarding bubble formation, reagent addition, resident time and a redesign of flotation machines, aiming to increase the recovery of extremely fine Willemite ore particles.

https://doi.org/10.1590/0370-44672018720069 1167 downloads

15.

Correlação entre parâmetros cardiovasculares e alterações glaucomatosas do nervo óptico em portadores de insuficiência cardíaca congestiva
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Libório, João Lucas de Oliveira Pegurin

; Ferreira Junior, José Paulo Pinotti

; Uneda, Lucas de Azevedo Melo

; Fraga, Guilherme Baptista Rosalem

; Felício, Eduardo Modenesi

; Valbon, Bruno de Freitas

Revista Brasileira de Oftalmologia

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Mar 2019, Volume 78 Nº 2 Páginas 122 - 126

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo Objetivos: Correlacionar parâmetros oftalmoscópicos e cardiovasculares em pacientes com diagnóstico de insuficiência cardíaca com fração de ejeção reduzida (ICFER) e avaliar a associação entre ICFER e alterações do nervo óptico sugestivas de glaucoma. Métodos: Estudo descritivo, observacional, prospectivo, composto por amostra 30 pacientes com diagnóstico de ICFER. Os pacientes foram submetidos ao exame oftalmológico, que incluiu biomicroscopia, avaliação da acuidade visual, aferição da PIO (pressão intraocular), gonioscopia e medida de ECC (espessura central corneana). A avaliação de parâmetros cardiovasculares, como PAM (pressão arterial média), FEVE (fração de ejeção do ventrículo esquerdo), comorbidades e tempo de diagnóstico de IC foi realizada a partir de revisão de prontuário médico. Arbitrariamente foi escolhido o olho esquerdo para análise estatística dos dados. A correlação estatística foi realizada através do teste de Spearman, e a comparação através do teste U de Mann-Whitney. Resultados: Observou-se uma alta prevalência de atrofia peripapilar (73,3%), além de uma correlação positiva, moderada e estatisticamente significativa entre FEVE e PPO (pressão de perfusão ocular) (r = 0,517; p = 0,004). Apesar da ausência de significância das comparações pelo Teste U de Mann-Whitney, evidenciou-se uma maior prevalência de atrofia peripapilar nos pacientes que apresentavam uma menor PAM, menor FEVE e menor PPO. Conclusão: A ICFER pode ser um fator de risco para o desenvolvimento de alterações glaucomatosas no disco do nervo óptico. A atrofia peripapilar e a baixa pressão de perfusão ocular resultantes do déficit contrátil cardíaco podem estar relacionadas com a teoria vascular do desenvolvimento do glaucoma de pressão.

Abstract Objectives: To correlate ophthalmoscopic and cardiovascular parameters in patients diagnosed with low-output heart failure (HFrEF) and to evaluate the association between HFrEF and glaucoma-suggestive alterations in the optic nerve. Methods: Descriptive, observational and prospective study, composed of 30 patients diagnosed with HFrEF. The patients were submitted to ophthalmologic examination, which included biomicroscopy, visual acuity, gonioscopy, intraocular pressure (IOP) and central corneal thickness (CCT) measurement. Their cardiovascular parameters evaluation, such as mean arterial pressure (MAP), left ventricular ejection fraction (LVEF), comorbidities and diagnosis time of HFrEF was performed upon a review over their medical chart. The left eye was arbitrarily chosen for statistical analysis of the data. Statistical correlation was performed using the Spearman test, while the comparison was performed using the Mann-Whitney U-test. Results: A high prevalence of peripapillary atrophy (73.3%) was observed, as well as a positive, moderate and statistically significant correlation between LVEF and ocular perfusion pressure (OPP) (r = 0.517; p = 0.004). Despite the lack of significance of the Mann-Whitney U-Test comparisons, a higher prevalence of peripapillary atrophy was found in patients with lower MAP, lower LVEF and lower OPP. Conclusion: HFrEF may be a risk factor for the development of glaucomatous changes in the optic nerve disc. The resulting peripapillary atrophy and low OPP from the contractile deficit may be related to the vascular theory about normal-tension glaucoma development.

https://doi.org/10.5935/0034-7280.20180109 2305 downloads

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