Pesquisa | SciELO

Abstract Natural compounds are possible alternatives for wound treatment, including Ilex paraguariensis, a plant with several pharmacological actions already reported, including anti-inflammatory, antibacterial, antioxidant, and healing activities. Therefore, this study aimed to perform a technological and scientific mapping of Ilex paraguariensis used for healing and/or analgesic purposes. Technological prospection was carried out in the Questel-Orbit system, while the scientific research was carried out in PubMed, Web of Science, and SCOPUS databases. The terms “Ilex paraguariensis”, “Yerba-mate”, “Painkiller”, “Analgesic”, “Wound”, “Healing”, and “Scar” were combined using Boolean operators “OR” and “AND”. The technological prospection resulted in 164 patents found initially. After sorting the abstracts, five patents were read entirely, of which three were selected. Such selected patents report using Ilex paraguariensis for analgesics, wound healing, personal care, and pharmaceutical applications. In addition, the scientific research showed a small number of studies aimed at using Ilex paraguariensis for healing and/or analgesic purposes. Among the 26 articles initially found, only 5 met the inclusion requirements. Scientific studies demonstrate that Ilex paraguariensis is used as an extract or drink, presenting promising results regarding analgesia, inflammation, and wound healing, using in vitro or in vivo models. Despite the potential of Ilex paraguariensis in skin wound therapy, our study demonstrates that few patents and scientific studies explore Ilex paraguariensis for this purpose. This fact may be an incentive for the development of further studies employing Ilex paraguariensis in cutaneous wound management and the pain associated with them. treatment reported antiinflammatory, antiinflammatory anti inflammatory, inflammatory anti-inflammatory antibacterial antioxidant activities Therefore andor purposes QuestelOrbit Questel Orbit system PubMed Science databases , paraguariensis” Yerbamate, Yerbamate Yerba mate “Yerba-mate” Painkiller, Painkiller “Painkiller” Analgesic, Analgesic “Analgesic” Wound, Wound “Wound” Healing, Healing “Healing” Scar “Scar OR “OR AND. AND . “AND” 16 abstracts entirely analgesics care applications addition 2 requirements drink analgesia inflammation models therapy purpose them “Yerba-mate “Painkiller “Analgesic “Wound “Healing “AND 1

https://doi.org/10.1590/1678-4324-2024230086

Brazilian evidence-based guideline for screening, diagnosis, treatment, and follow-up of metabolic dysfunction-associated steatotic liver disease (MASLD) in adult individuals with overweight or obesity: A joint position statement from the Brazilian Society of Endocrinology and Metabolism (SBEM), Brazilian Society of Hepatology (SBH), and Brazilian Association for the Study of Obesity and Metabolic Syndrome (Abeso) evidencebased evidence based screening diagnosis treatment followup follow up dysfunctionassociated dysfunction associated MASLD (MASLD obesity SBEM, SBEM , (SBEM) SBH, SBH (SBH) Abeso (Abeso (SBEM (SBH
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Moreira, Rodrigo Oliveira

; Valerio, Cynthia Melissa

; Villela-Nogueira, Cristiane Alves

; Cercato, Cintia

; Gerchman, Fernando

; Lottenberg, Ana Maria Pita

; Godoy-Matos, Amélio Fernando

; Oliveira, Ricardo de Andrade

; Mello, Carlos Eduardo Brandão

; Álvares-da-Silva, Mário Reis

; Leite, Nathalie Carvalho

; Cotrim, Helma Pinchemel

; Parisi, Edison Roberto

; Silva, Giovanni Faria

; Miranda, Paulo Augusto Carvalho

; Halpern, Bruno

; Oliveira, Claudia Pinto

Archives of Endocrinology and Metabolism

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2023, Volume 67 Nº 6 elocation e230123

Resumo: En | Texto: En | PDF: En

ABSTRACT Introduction: Metabolic dysfunction-associated steatotic liver disease (MASLD), previously known as Nonalcoholic fatty liver disease (NAFLD), is one of the most common hepatic diseases in individuals with overweight or obesity. In this context, a panel of experts from three medical societies was organized to develop an evidence-based guideline on the screening, diagnosis, treatment, and follow-up of MASLD. Material and methods: A MEDLINE search was performed to identify randomized clinical trials, meta-analyses, cohort studies, observational studies, and other relevant studies on NAFLD. In the absence of studies on a certain topic or when the quality of the study was not adequate, the opinion of experts was adopted. Classes of Recommendation and Levels of Evidence were determined using prespecified criteria. Results: Based on the literature review, 48 specific recommendations were elaborated, including 11 on screening and diagnosis, 9 on follow-up, 14 on nonpharmacologic treatment, and 14 on pharmacologic and surgical treatment. Conclusions: A literature search allowed the development of evidence-based guidelines on the screening, diagnosis, treatment, and follow-up of MASLD in individuals with overweight or obesity. Introduction dysfunctionassociated dysfunction associated MASLD, , (MASLD) NAFLD, NAFLD (NAFLD) obesity context evidencebased evidence based diagnosis treatment followup follow up methods trials metaanalyses, metaanalyses meta analyses, analyses meta-analyses adequate adopted criteria Results review 4 elaborated 1 followup, up, Conclusions (MASLD (NAFLD

https://doi.org/10.20945/2359-4292-2023-0123

Mulher do fim do mundo: violência feminicida contra a saúde da mulher negra
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Costa, Mariana Freitas da

; Augusto, Cristiane Brandão

; Marques, Maria Celeste Simões

Saúde em Debate

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2023, Volume 47 Nº spe1 elocation e9100

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO Este artigo se dedica a dialogar sobre a violência feminicida e algumas de suas manifestações contra as mulheres negras. Tem-se como objetivo evidenciar de que forma as vivências cotidianas e as relações sociais e de poder afetam esse grupo populacional e banalizam a violência que as acomete, legitimando altas taxas de mortalidade por diferentes causas evitáveis, sem que estas sejam consideradas um problema de saúde pública. O texto demonstra, a partir de um levantamento bibliográfico, a evitabilidade de mortes em casos de neoplasias malignas, HIV/aids e suicídio resultantes da mitigação ao acesso à saúde, associada a subjugações no sistema patriarcal racista. Negligência e descaso, motivados por racismo e misoginia estruturais, conformam o ‘fazer morrer’ de mulheres negras revelado por uma necropolítica de diagnósticos tardios, falhas em campanhas de conscientização e prevenção, falta de acolhimento e de políticas adequadas a essa população. Relacionando tais violações ao direito à saúde com músicas de Elza Soares, pretende-se trazer a arte como instrumento de denúncia e como recuperação de vozes silenciadas.

ABSTRACT This article discusses feminicidal violence and some of its manifestations against Black women. It aims to highlight how everyday experiences and social and power relationships affect this population group and trivialize the violence that affects them, legitimizing high mortality rates from different preventable causes without these being considered a public health problem. Based on a bibliographical survey, the text shows the avoidability of deaths in cases of malignant neoplasms, HIV/AIDS, and suicide resulting from the mitigated access to healthcare associated with subjugations in the racist patriarchal system. Negligence and disregard motivated by structural racism and misogyny shape the death of Black women, revealed by a necropolitics of late diagnoses, failures in sensitization and prevention campaigns, lack of receptiveness, and adequate policies for that population. Relating such violations of the right to health with songs by Elza Soares, this study aims to bring art as an instrument of denunciation and a revival of silenced voices.

https://doi.org/10.1590/2358-28982023e19100p

Mulher do fim do mundo: violência feminicida contra a saúde da mulher negra mundo
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Costa, Mariana Freitas da

; Augusto, Cristiane Brandão

; Marques, Maria Celeste Simões

Saúde em Debate

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2023, Volume 47 Nº spe1 elocation e9100

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

https://doi.org/10.1590/2358-28982023e19100p

Análise clínico-epidemiológica de pacientes HIV positivos internados em uma Unidade de Terapia de Queimados
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SECANHO, MURILO SGARBI

; MENEZES NETO, BALDUINO FERREIRA DE

; OLIVEIRA, ANA BEATRIZ PEDROSO MACIEL DE

; CHEQUIM, MERIMAR MARIA

; CARVALHO, LAISA BRANDÃO

; MORAGAS, WEBER RIBOLLI

; ROCHA, CRISTIANE

; PALHARES, ARISTIDES AUGUSTO

Revista Brasileira de Cirurgia Plástica

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Abr 2022, Volume 37 Nº 2 Páginas 199 - 203

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO Introdução: A infecção pelo HIV e as queimaduras são um problema comum de saúde pública, principalmente em países de baixa e média renda. Há uma escassez na literatura sobre a epidemiologia de pacientes HIV positivos hospitalizados em unidades de queimados. O objetivo deste estudo é avaliar dados clínicoepidemiológicos de pacientes HIV positivos internados em uma Unidade de Terapia de Queimaduras. Métodos: Realizada análise retrospectiva de pacientes com diagnóstico de HIV internados na Unidade de Terapia de Queimados do Hospital Estadual de Bauru entre os anos de 2008 e 2018. Resultados: No total, foram revisados 2364 prontuários e encontrados 14 (0,6%) pacientes com diagnóstico de HIV. A idade média foi 43,1 anos. Quanto ao gênero, nove (64,3%) eram masculinos e cinco (35,7%) femininos. O mecanismo mais comum foi por chama direta em 11 (78,7%) casos. A etiologia foi álcool (42,9%) em seis pacientes, em três explosão (21,5%) e os demais foram gasolina, cigarro e contato com escapamento, todos com um (7,1%) caso. A causa mais comum foi acidente, em nove (64,3%) casos, dois (14,3%) tentativa de homicídio, um (7,1%) autoextermínio e dois (14,3%) casos sem informação. Em relação à superfície corporal queimada (%SCQ), cinco (37,5%) apresentavam queimaduras de 0-10%, três (21,4%) de 11-20% e cinco (35,7%) maiores que 20%, e em um era desconhecida. Quatro (28,6%) apresentaram lesões de vias aéreas. Dois (14,3%) pacientes foram a óbito. Conclusão: A prevalência de pacientes HIV positivos queimados internados em uma unidade especializada para este tratamento se assemelha à nacional, com características semelhantes em relação a idade e gênero.

ABSTRACT Introduction: HIV infection and burns are common public health issues, especially in low- and middle-income countries. There is a paucity in the literature evaluating the epidemiology of burns hospitalization in HIV patients. This study aims to evaluate the clinical and epidemiological profile of HIV-positive patients hospitalized in a Burn Therapy Unit. Methods: A retrospective analysis of burn patients diagnosed with HIV was performed at the Therapy Unit of the State Hospital of Bauru between 2008 and 2018. Results: 2,364 medical records were reviewed, and 14 (0.6%) patients were diagnosed with HIV. The mean age was 43.1 years. Regarding gender, nine (64.3%) were male, and five (35.7%) were female. The most common mechanism was direct flame in 11 (78.7%) cases. The etiology was alcohol (42.9%) in six patients, in three explosions (21. 5%), and the others were gasoline, cigarettes and contact with exhaustion, all with one (7.1%) case. When the cause of these burns was evaluated, nine (64.3%) were due to accidents, either at work or home, two (14.3%) for attempted murder, one (7.1%) self-extermination, and two (14.3%) cases had no information. Regarding total burn surface area, five (37.5%) had burns of 0-10%, three (21.4%) 11-20% and five (35.7%) greater than 20%, and one was unknown. Four (28.6%) showed airway lesions. Two (14.3%) patients died. Conclusion: The prevalence of burned HIV-positive patients admitted to a specialized unit for this treatment is like the national one, with similar characteristics concerning age and gender.

https://doi.org/10.5935/2177-1235.2022rbcp0033

Diretrizes Brasileiras de Hipertensão Arterial – 2020
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Barroso, Weimar Kunz Sebba

; Rodrigues, Cibele Isaac Saad

; Bortolotto, Luiz Aparecido

; Mota-Gomes, Marco Antônio

; Brandão, Andréa Araujo

; Feitosa, Audes Diógenes de Magalhães

; Machado, Carlos Alberto

; Poli-de-Figueiredo, Carlos Eduardo

; Amodeo, Celso

; Mion Júnior, Décio

; Barbosa, Eduardo Costa Duarte

; Nobre, Fernando

; Guimarães, Isabel Cristina Britto

; Vilela-Martin, José Fernando

; Yugar-Toledo, Juan Carlos

; Magalhães, Maria Eliane Campos

; Neves, Mário Fritsch Toros

; Jardim, Paulo César Brandão Veiga

; Miranda, Roberto Dischinger

; Póvoa, Rui Manuel dos Santos

; Fuchs, Sandra C

; Alessi, Alexandre

; Lucena, Alexandre Jorge Gomes de

; Avezum, Alvaro

; Sousa, Ana Luiza Lima

; Pio-Abreu, Andrea

; Sposito, Andrei Carvalho

; Pierin, Angela Maria Geraldo

; Paiva, Annelise Machado Gomes de

; Spinelli, Antonio Carlos de Souza

; Nogueira, Armando da Rocha

; Dinamarco, Nelson

; Eibel, Bruna

; Forjaz, Cláudia Lúcia de Moraes

; Zanini, Claudia Regina de Oliveira

; Souza, Cristiane Bueno de

; Souza, Dilma do Socorro Moraes de

; Nilson, Eduardo Augusto Fernandes

; Costa, Elisa Franco de Assis

; Freitas, Elizabete Viana de

; Duarte, Elizabeth da Rosa

; Muxfeldt, Elizabeth Silaid

; Lima Júnior, Emilton

; Campana, Erika Maria Gonçalves

; Cesarino, Evandro José

; Marques, Fabiana

; Argenta, Fábio

; Consolim-Colombo, Fernanda Marciano

; Baptista, Fernanda Spadotto

; Almeida, Fernando Antonio de

; Borelli, Flávio Antonio de Oliveira

; Fuchs, Flávio Danni

; Plavnik, Frida Liane

; Salles, Gil Fernando

; Feitosa, Gilson Soares

; Silva, Giovanio Vieira da

; Guerra, Grazia Maria

; Moreno Júnior, Heitor

; Finimundi, Helius Carlos

; Back, Isabela de Carlos

; Oliveira Filho, João Bosco de

; Gemelli, João Roberto

; Mill, José Geraldo

; Ribeiro, José Marcio

; Lotaif, Leda A. Daud

; Costa, Lilian Soares da

; Magalhães, Lucélia Batista Neves Cunha

; Drager, Luciano Ferreira

; Martin, Luis Cuadrado

; Scala, Luiz César Nazário

; Almeida, Madson Q.

; Gowdak, Marcia Maria Godoy

; Klein, Marcia Regina Simas Torres

; Malachias, Marcus Vinícius Bolívar

; Kuschnir, Maria Cristina Caetano

; Pinheiro, Maria Eliete

; Borba, Mario Henrique Elesbão de

; Moreira Filho, Osni

; Passarelli Júnior, Oswaldo

; Coelho, Otavio Rizzi

; Vitorino, Priscila Valverde de Oliveira

; Ribeiro Junior, Renault Mattos

; Esporcatte, Roberto

; Franco, Roberto

; Pedrosa, Rodrigo

; Mulinari, Rogerio Andrade

; Paula, Rogério Baumgratz de

; Okawa, Rogério Toshiro Passos

; Rosa, Ronaldo Fernandes

; Amaral, Sandra Lia do

; Ferreira-Filho, Sebastião R.

; Kaiser, Sergio Emanuel

; Jardim, Thiago de Souza Veiga

; Guimarães, Vanildo

; Koch, Vera H.

; Oigman, Wille

; Nadruz, Wilson

Arquivos Brasileiros de Cardiologia

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Mar 2021, Volume 116 Nº 3 Páginas 516 - 658

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

https://doi.org/10.36660/abc.20201238 10948 downloads

Influence of antihypertensive pharmacological treatment on the acute cardiovascular responses to the resistance exercise in hypertensive middle-aged women
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Pereira, Gilene de Jesus

; Miguel-dos-Santos, Rodrigo

; Santana-Filho, Valter Joviniano de

; Barreto-Filho, José Augusto Soares

; Santos, Cristiane Kelly Aquino dos

; Santana, Mylena Maria Salgueiro

; Mota, Marcelo Mendonça

; Silva, Tharciano Luiz Teixeira Braga da

; Araujo, Silvan Silva de

; Tavares Junior, José Carlos

; Wichi, Rogério Brandão

Motriz: Revista de Educação Física

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2020, Volume 26 Nº 3 elocation e10200018

Resumo: En | Texto: En | PDF: En

Abstract Aim: To investigate the hypothesis that the resistance exercise (RE) may be safer if the blood pressure (BP) is properly controlled through antihypertensive pharmacological treatment in hypertensive middle-aged women. Methods: The final sample was comprised of 19 hypertensive women, with an average age of 58±5 years and a body mass index of 29±5 Kg/m2. They were divided into three groups: controlled (n=6), uncompensated (n=8), and untreated (n=5). The subjects from all groups were submitted to a test of maximal strength on extensor chair and held a session of RE (knee extension, 3x12 to 60% 1RM) and the cardiovascular response (BP and heart rate) was monitored continuously by photoplethysmography during exercise and until five minutes after exercise (recovery). Results: Systolic BP (SBP) and diastolic BP (DBP) responses were lower in the controlled group compared to the other groups (p<0.05). The heart rate was not different between groups, while the double product was lower in the controlled group compared to the untreated group (p<0.05). The SBP and DBP peaks were lower in the controlled group compared to the other groups (p<0.05). Conclusion: The BP increases significantly during RE when the hypertension is not controlled. Pharmacological control was shown to be effective in preventing the increase of BP during the performance of the RE.

https://doi.org/10.1590/s1980-6574202000030018 390 downloads

Maré de Mulheres: reflexões sobre a justiça para mulheres em situação de violência numa favela carioca
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Santiago, Marisa Antunes

; Gonçalves, Hebe Signorini

; Augusto, Cristiane Brandão

Ex aequo

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Dez 2019, Nº 40 Páginas 123 - 140

Resumo: Es Pt En | Texto: Es Pt En | PDF: Es | PDF: Pt | PDF: En

El presente trabajo tiene como objetivo reflexionar sobre estrategias de enfrentamiento a la violencia doméstica y familiar contra la mujer, a partir de una investigación realizada en el Centro de Referencia de Atención a la Mujer en el Complejo de Favelas da Maré, en Río de Janeiro. A través de la visión de las/os profesionales que allí actúan, procuramos demostrar el perfil de las mujeres que buscan el servicio, las percepciones sobre violencia, las principales dificultades en cuanto al acceso a la justicia oficial y las metodologías alternativas al sistema penal.

O presente trabalho objetiva refletir sobre estratégias de enfrentamento à violência doméstica e familiar contra a mulher, a partir de pesquisa realizada no Centro de Referência de Atenção à Mulher no Complexo de Favelas da Maré, no Rio de Janeiro. Através da visão das/os profissionais que aí atuam, procuramos demonstrar o perfil das mulheres que procuram o serviço, as percepções sobre violência, as principais dificuldades quanto ao acesso à Justiça oficial e as metodologias alternativas ao sistema penal.

The present study aims to reflect on strategies for facing domestic and family violence against women, based on a research carried out at the Reference Center for Women's Care in the Maré complex of favelas in Rio de Janeiro. Through the vision of professionals who work there, we intend to demonstrate the profile of women who seek the service, the perceptions about violence, the main difficulties regarding access to official Justice and alternative methodologies to the Penal System.

https://doi.org/10.22355/exaequo.2019.40.08 1228 downloads

Epidemiological aspects of American cutaneous leishmaniasis (ACL) in an endemic area of forest extractivist culture in western Brazilian Amazonia
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Brilhante, Andreia Fernandes

; Melchior, Leonardo Augusto Kohatsu

; Nunes, Vânia Lúcia Brandão

; Cardoso, Cristiane de Oliveira

; Galati, Eunice Aparecida Bianchi

Revista do Instituto de Medicina Tropical de São Paulo

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2017, Volume 59 elocation e12

Resumo: En | Texto: En | PDF: En

ABSTRACT The study sought to analyze clinical and epidemiological aspects of cutaneous leishmaniasis (CL) in Xapuri, Acre, Brazil. Data from 2008 to 2014 registered in the notification records of the disease of the Information System of the Complaints of Notification (SINAN), and the data of the Information Department of the Unified Health System (DATASUS) available from 2007 to 2013 were used and analyzed in the light of the statistics of the temporal series by the Prais-Winsten method and chi-squared test. A total of 906 cases were registered with 60.2% occurring in men and 39.7% in women. The groups from 0 to 4 years of age (48.0%) and from 5 to 19 years of age (23.3%) were the most affected. Regarding the clinical forms, 77.7% presented CL and 22.3% mucocutaneous leishmaniasis (MCL). Among the 896 cases with information on the diagnostic methods used, Montenegro’s skin test predominated (66.4%), with a positive result of 95.8% for CL and 99.3% for MCL. Treatment with N-methylglucamine antimony was performed in 99.4% of the cases, but discontinuously used in the majority of patients. This study presents information which may be used as a tool for the epidemiological surveillance and control of the disease in Xapuri, a region which depends essentially on forest resources and ecological tourism.

https://doi.org/10.1590/s1678-9946201759012 3301 downloads

10.

Nina Rodrigues e a patologização do crime no Brasil
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Augusto, Cristiane Brandão

; Ortega, Francisco

Revista Direito GV

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Jun 2011, Volume 7 Nº 1 Páginas 221 - 236

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Este artigo se dedica à análise do movimento de "patologização" do criminoso por uma leitura histórica do impacto do "cientificismo cerebral" na esfera criminal. mais particularmente, atenta-se para a recepção das teorias de matriz lombrosiana pela criminologIa brasileira do século XIX, na qual se vê o microcosmo do conflito de interesses de classes e raças mediado pela autoridade médica que, na sua crença científica (ou na sua filiação ideológica), procurava esclarecer os limites entre a falta moral e a loucura - ou os dois (loucura moral) como doença ou como pura perversidade - e procurava apontar para os juízes a forma correta (científica) de se sancionar ou de se tratar a loucura.

The current work aims at performing an analysis of the criminals "pathologization" movement by means of a historical reading of the impact of ''brain scientificism" in the criminal sphere. more particularly, there is an emphasis on the reception of the lombrosionism matrix theories in 1 9th-century brazilian criminology, in which we can see the microcosms of classes and races conflicts of interests, mediated by the medical authority who, in his scientific beliefs ¡or in his ideological filiations), looked for illuminate the limits between the moral fault and the madness - or the both (moral madness) as pathology or as pure perversity -and tried to show the correct form ¡scientific} of punishing or treating.

9762 downloads Citado 2 vezes em SciELO

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