Resumo Objetivou-se realizar uma análise espacial da taxa de mortalidade hospitalar (TMH) por síndrome respiratória aguda grave (SRAG) atribuída à COVID-19 em crianças e adolescentes no Brasil no período de 2020 a 2021. Utilizou-se o método de cluster para agrupar as unidades federativas (UFs) com base na TMH. Em 2020, clusters com altas TMHs foram formados por UFs Norte/Nordeste. Em 2021, houve redução na TMH. Os clusters com maiores taxas permaneceram na região N/NE. Diferenças regionais foram observadas nas TMHs. Os achados podem refletir as desigualdades sociais e o acesso à atenção hospitalar, principalmente na faixa etária de menores de 1 ano pela gravidade da doença neste grupo.

Abstract The objective was to perform a spatial analysis of the hospital mortality rate (HMR) due to severe acute respiratory syndrome (SARS) attributed to COVID-19 among children and adolescents in Brazil from 2020 to 2021. A cluster method was used to group federal units (FUs) based on HMR. In 2020, clusters with high HMRs were formed by north/northeast FUs. In 2021, there was a reduction in HMR. Clusters with higher rates remained in the N/NE region. Regional differences were observed in the HMR. The findings may reflect social inequalities and access to hospital care, especially in the under 1-year-old age group due to the severity of the disease in this group.

Abstract The objective was to perform a spatial analysis of the hospital mortality rate (HMR) due to severe acute respiratory syndrome (SARS) attributed to COVID-19 among children and adolescents in Brazil from 2020 to 2021. A cluster method was used to group federal units (FUs) based on HMR. In 2020, clusters with high HMRs were formed by north/northeast FUs. In 2021, there was a reduction in HMR. Clusters with higher rates remained in the N/NE region. Regional differences were observed in the HMR. The findings may reflect social inequalities and access to hospital care, especially in the under 1-year-old age group due to the severity of the disease in this group.

Resumo Objetivou-se realizar uma análise espacial da taxa de mortalidade hospitalar (TMH) por síndrome respiratória aguda grave (SRAG) atribuída à COVID-19 em crianças e adolescentes no Brasil no período de 2020 a 2021. Utilizou-se o método de cluster para agrupar as unidades federativas (UFs) com base na TMH. Em 2020, clusters com altas TMHs foram formados por UFs Norte/Nordeste. Em 2021, houve redução na TMH. Os clusters com maiores taxas permaneceram na região N/NE. Diferenças regionais foram observadas nas TMHs. Os achados podem refletir as desigualdades sociais e o acesso à atenção hospitalar, principalmente na faixa etária de menores de 1 ano pela gravidade da doença neste grupo.

Abstract Mortality caused by the COVID-19 pandemic has impacted indicators of Years of Potential Life Lost (YPLL) worldwide. This study aimed to estimate the YPLL due to mortality caused by COVID-19, according to sex, age group, and race/color in Brazil, from March 2020 to December 2021. Deaths caused by COVID-19 were characterized, in which the rates and ratios of standardized YPLL rates, the average number of years of potential life lost (ANYPLL), and the average age at death (AAD) were estimated and compared. Overall, 13,776,969.50 potential years of life were lost, which resulted in an average loss of 22.5 potential years not lived. A greater loss of potential years of life was identified in men (58.12%) and in the age groups from 0 to 59 years in the black (58.92%) and indigenous (63.35%) populations, while in the age groups of 60 years and over, a greater loss of YPLL was observed in the white (45.89%) and yellow (53.22%) populations. Women recorded the highest ADD, with the exception of indigenous women. White men (1.63), brown men (1.59), and black men (1.61) had the highest rates when compared to white women. Although COVID-19 has a greater impact on the elderly, it was the black and indigenous populations under the age of 60 who had the greatest loss of potential years of life. COVID19 COVID 19 COVID-1 (YPLL worldwide COVID19, 19, sex group racecolor race color Brazil 202 2021 characterized ANYPLL, ANYPLL , (ANYPLL) AAD (AAD Overall 1377696950 13 776 969 50 13,776,969.5 225 22 5 22. lived 58.12% 5812 58 12 (58.12% 58.92% 5892 92 (58.92% 63.35% 6335 63 35 (63.35% 6 over 45.89% 4589 45 89 (45.89% 53.22% 5322 53 (53.22% ADD women 1.63, 163 1.63 1 (1.63) 1.59, 159 1.59 (1.59) 1.61 161 61 (1.61 elderly COVID1 COVID- 20 (ANYPLL 137769695 77 96 13,776,969. 2 58.12 581 (58.12 58.92 589 9 (58.92 63.35 633 3 (63.35 45.89 458 4 8 (45.89 53.22 532 (53.22 16 1.6 (1.63 15 1.5 (1.59 (1.6 13776969 7 13,776,969 58.1 (58.1 58.9 (58.9 63.3 (63.3 45.8 (45.8 53.2 (53.2 1. (1.5 (1. 1377696 13,776,96 58. (58. 63. (63. 45. (45. 53. (53. (1 137769 13,776,9 (58 (63 (45 (53 ( 13776 13,776, (5 (6 (4 1377 13,776 137 13,77 13,7 13,

Resumo A mortalidade provocada pela pandemia da COVID-19 tem produzido impactos aos indicadores de Anos Potenciais de Vida Perdidos (APVP) em nível mundial. Objetiva-se estimar os APVP devido à mortalidade por COVID-19, segundo sexo, faixa etária e raça/cor, no período de março de 2020 a dezembro de 2021, no Brasil. Foram caracterizadas as mortes por COVID-19, estimadas e comparadas as taxas e razão de taxas padronizadas de APVP, a média de anos potenciais de vida não vividos (APVNV) e a idade média do óbito (IMO). No geral, foram perdidos 13.776.969,50 anos potenciais de vida, o que determinou uma perda média de 22,5 anos potenciais não vividos. Houve maior perda de anos potenciais de vida nos homens (58,12%) e nas faixas etárias de 0 a 59 anos nas populações negra (58,92%) e indígena (63,35%), enquanto nas faixas etárias de 60 anos e mais foi observada maior perda de APVP nas populações branca (45,89%) e amarela (53,22%). As mulheres registraram as maiores IMO, com exceção das mulheres indígenas. Homens brancos (1,63), pardos (1,59) e pretos (1,61) tiveram as maiores taxas em comparação às mulheres brancas. Apesar da COVID-19 ter tido maior impacto em idosos, foram as populações negra e indígena na faixa de menos de 60 anos quem teve maior perda de anos potenciais de vida. COVID19 COVID 19 COVID-1 (APVP mundial Objetivase Objetiva se COVID19, 19, sexo raçacor raça cor raça/cor 202 2021 Brasil APVNV (APVNV IMO. IMO . (IMO) geral 1377696950 13 776 969 50 13.776.969,5 225 22 5 22, 58,12% 5812 58 12 (58,12% 58,92% 5892 92 (58,92% 63,35%, 6335 63,35% , 63 35 (63,35%) 6 45,89% 4589 45 89 (45,89% 53,22%. 5322 53,22% 53 (53,22%) indígenas 1,63, 163 1,63 1 (1,63) 1,59 159 (1,59 1,61 161 61 (1,61 brancas idosos COVID1 COVID- 20 (IMO 137769695 77 96 13.776.969, 2 58,12 581 (58,12 58,92 589 9 (58,92 633 63,35 3 (63,35% 45,89 458 4 8 (45,89 532 53,22 (53,22% 16 1,6 (1,63 1,5 15 (1,5 (1,6 13776969 7 13.776.969 58,1 (58,1 58,9 (58,9 63,3 (63,35 45,8 (45,8 53,2 (53,22 1, (1, 1377696 13.776.96 58, (58, 63, (63,3 45, (45, 53, (53,2 (1 137769 13.776.9 (58 (63, (45 (53, ( 13776 13.776. (5 (63 (4 (53 1377 13.776 (6 137 13.77 13.7 13.

ABSTRACT Aristolochia hypoglauca and A. paulistana (Aristolochiaceae) are two species that inhabit the Brazilian Atlantic Forest. They highly resemble each other especially on the size and overall shape of the caudate perianth, which causes confusion in herbaria determinations. We applied geometric morphometrics (GM) to overcome this taxonomic uncertainty. GM was based on the landmark method applied to leaves of all specimens available mostly in Brazilian herbaria. The GM results supported the recognition of the two species, as the two principal components were responsible for 94.97% of the variation assessed through the principal component analysis (PCA). The Discriminant Function and the Cross-validation tests resulted in the maximum percentage of correctly classified cases (100%). The Procrustes distance (0.2252; p< 0.0001), and the Mahalanobis Distance (8.4473; p< 0.0001) provide statistical support for leaf shape differences with taxonomic significance. Thus, we revisit the taxonomy and comparative morphology of both species, and compare them with other Aristolochia species with caudate floral limb native to Brazil, and commented the phenology, distribution and habitat, and conservation status. Additionally, we proposed the epitypification of A. hypoglauca, given that the holotype does not fulfill the purpose of precise application of the name. A Aristolochiaceae (Aristolochiaceae Forest perianth determinations (GM uncertainty 9497 94 97 94.97 PCA. PCA . (PCA) Crossvalidation Cross validation 100%. 100 100% (100%) 0.2252 02252 0 2252 (0.2252 p 0.0001, 00001 0.0001 , 0001 8.4473 84473 8 4473 (8.4473 significance Thus Brazil phenology habitat status Additionally name 949 9 94.9 (PCA 10 (100% 0.225 0225 225 (0.225 0000 0.000 000 8.447 8447 447 (8.447 94. 1 (100 0.22 022 22 (0.22 0.00 00 8.44 844 44 (8.44 (10 0.2 02 2 (0.2 0.0 8.4 84 4 (8.4 (1 0. (0. 8. (8. ( (0 (8

ABSTRACT Waste frying oil may serve as a viable alternative to fresh vegetable oils, potentially reducing environmental impacts and animal feed costs. This study aimed to assess the effects of incorporating waste frying oil into sheep diets and to determine the optimal dietary oil concentration. We evaluated intake and apparent digestibility using 25 uncastrated Santa Inês male sheep (average, 90 d of age; 20 ± 3.56 kg) in a randomized block design over a 21-d experimental period. The sheep were housed in individual metabolic cages and fed diets with a 50:50 roughage-to-concentrate ratio twice daily. Diets included waste frying oil at concentrations of 0, 2, 4, 6, and 8% of the total dry matter. Animals receiving higher concentrations of waste frying oil exhibited lower nutrient intake (p < 0.05) compared to those with up to 4% inclusion. Nutrient digestibility decreased linearly (p < 0.05) with increasing oil content, except for ether extract digestibility (p = 0.02), which improved. Although the addition of oil increased the concentration of total digestible nutrients, the intake of total digestible nutrients was not maintained or enhanced at 6% and 8% oil (p = 0.82). Including up to 4% waste frying oil in sheep diets is feasible without compromising nutrient intake and digestibility. oils costs 2 average, average (average 9 age 356 3 56 3.5 kg 21d 21 period 5050 50 50:5 roughagetoconcentrate roughage concentrate daily 0 4 6 8 matter p 0.05 005 05 inclusion content 0.02, 002 0.02 , 02 0.02) improved 0.82. 082 0.82 . 82 0.82) 35 5 3. 505 50: 0.0 00 08 0.8 0.

RESUMO O óleo de residual de fritura pode ser uma opção viável para diminuir os impactos ambientais e os gastos com alimentação animal substituindo óleos vegetais in natura. Com isso, o presente trabalho objetivou avaliar o efeito da inclusão de óleo residual de fritura em dietas para ovinos e determinar a concentração ideal de óleo na dieta. Para o ensaio de consumo e digestibilidade aparente foram utilizados 25 cordeiros machos, inteiros, da raça Santa Inês com idade média de 90 dias e 20 kg (± 3,56), distribuídos em delineamento em blocos casualizados. O experimento teve duração de 21 dias. Os animais foram alojados em gaiolas metabólicas e alimentados duas vezes ao dia com dietas formuladas na proporção volumoso/concentrado de 50:50. O óleo residual de fritura integrou as dietas nas concentrações 0, 2, 4, 6 e 8% da matéria seca total. Os animais que receberam dietas com maiores concentrações de óleo residual de fritura apresentaram menor consumo dos nutrientes em contraste às dietas que continham até 4% de inclusão. A digestibilidade dos nutrientes diminuiu linearmente com a adição do óleo, com exceção a digestibilidade do extrato etéreo que foi maior. Apesar da maior concentração de Nutrientes Digestíveis Totais com a adição de óleo, esta não foi suficiente para manter ou aumentar o consumo de NDT nas dietas com 6 e 8% de óleo. A inclusão de até 4% de óleo residual de fritura, na dieta de ovinos, pode ser utilizada sem comprometer o consumo e a digestibilidade dos nutrientes. natura isso 2 machos inteiros 9 ± ( 3,56, 356 3,56 , 3 56 3,56) casualizados volumosoconcentrado volumoso concentrado 5050. 5050 50 50. 50:50 0 4 8 total 35 3,5 5 505 50:5 3, 50:

Abstract An adopted animal is considered a grand gesture with significant social responsibility since it needs daily care and affection from the adopter. Far beyond appearance and aesthetic issues, the adopter must consider their natural conditions, respecting the specific characteristics of the animal. The lack of expertise in choosing the animal can lead to an irresponsible and fruitless adoption, compromising the animal’s quality of life. Animal adoption portals are prone to this problem if they do not provide controls that try to approximate the adopter’s real motivations and conditions with the animal’s characteristics. Faced with this problem, this article proposes a content-based recommendation system to suggest animals for users to consume drugs, applying the weighted cosine technique. The weighting is fundamental in calculating the similarity between the users’ emotions and the animal’s characteristics. The experiments increased the accuracy of the recommendations when weighting is applied over the traditional method without considering the prescribed method of users by specific characteristics of the animals to be adopted. issues s life adopters contentbased content based drugs technique

Resumo A adoção animal é considerada um gesto grandioso que carrega consigo grande responsabilidade social, visto que um animal precisa dos cuidados e carinho diário do adotante. Muito além da aparência e questões estéticas, é essencial que o adotante considere suas reais condições respeitando as características específicas do animal. A falta de perícia na escolha do animal pode acarretar uma adoção irresponsável e infrutuosa, comprometendo a qualidade de vida do animal. Portais de adoção de animais são suscetíveis a esse problema se não fornecerem mecanismos que tentem aproximar as reais preferências e condições do adotante com as características do animal. Diante dessa problemática, este artigo propõe um sistema de recomendação baseado em conteúdo que visa sugerir animais para adoção considerando as preferências dos adotantes, aplicando a técnica do cosseno ponderado. A ponderação é fundamental no cálculo de similaridade entre as preferências dos adotantes e das características do animal. Os experimentos realizados apontam um aumento de precisão das recomendações quando a ponderação é aplicada sobre o método tradicional sem considerar as preferências do adotante por determinadas características dos animais a serem adotados. social estéticas infrutuosa problemática ponderado adotados

Abstract This study investigated for the first time the effectiveness of therapeutic baths with essential oil (EO) of Piper hispidum against monogeneans Anacanthorus spathulatus, Notozothecium janauachensis, Mymarothecium boegeri and Linguadactyloides brinkmanni from the gills of Colossoma macropomum, as well as the hematological and histological effects on this fish. In therapeutic baths, 100 mg/L of P. hispidum essential oil and two control groups (water from the culture tank and water from the culture tank with 70% alcohol) were exposed for 1 h/day, with intervals of 48 hours for 3 days, and three replicates each were used. Therapeutic baths with 100 mg/L of P. hispidum essential oil had an efficacy of 78.6% against monogeneans. The toxicity of this essential oil was low, since there were a few physiological and histopathological changes that did not compromise the functioning of the gills of the fish. Therefore, 100 mg/L of P. hispidum essential oil was effective for controlling monogeneans in C. macropomum, when short therapeutic baths were used without compromising the health of the exposed fish. EO (EO spathulatus janauachensis macropomum fish 10 mgL mg L P 70 alcohol hday h day h/day 4 days 786 78 6 78.6 low Therefore C 7 78.

Resumo Este estudo investigou pela primeira vez, a eficácia de banhos terapêuticos com óleo essencial (OE) de Piper hispidum contra monogenéticos Anacanthorus spathulatus, Notozothecium janauachensis, Mymarothecium boegeri e Linguadactyloides brinkmanni das brânquias de Colossoma macropomum, bem como os efeitos hematológicos e histológicos neste peixe. Foram usados 100 mg/L de óleo essencial de P. hispidum e dois grupos controles (água do tanque de cultivo e água do tanque de cultivo com álcool 70%) expostos durante 1 hora por dia, com intervalos de 48 horas durante 3 dias, três repetições cada. Banhos terapêuticos com 100 mg/L de OE de P. hispidum tiveram uma eficácia de 78,6% contra monogenéticos. A toxicidade foi baixa, pois ocorreram poucas alterações fisiológicas e histopatológicas que não comprometeram o funcionamento das brânquias dos peixes. Portanto, houve eficácia de 100 mg/L de OE de P. hispidum para controle de monogenéticos em C. macropomum, quando usados banhos terapêuticos curtos sem prejudicar a saúde dos peixes expostos. vez (OE spathulatus janauachensis macropomum peixe 10 mgL mg L P 70% 70 dia 4 dias cada 786 78 6 78,6 baixa Portanto C 7 78,

Abstract The objective was to perform a spatial analysis of the hospital mortality rate (HMR) due to severe acute respiratory syndrome (SARS) attributed to COVID-19 among children and adolescents in Brazil from 2020 to 2021. A cluster method was used to group federal units (FUs) based on HMR. In 2020, clusters with high HMRs were formed by north/northeast FUs. In 2021, there was a reduction in HMR. Clusters with higher rates remained in the N/NE region. Regional differences were observed in the HMR. The findings may reflect social inequalities and access to hospital care, especially in the under 1-year-old age group due to the severity of the disease in this group. HMR (HMR SARS (SARS COVID19 COVID 19 COVID-1 202 2021 FUs (FUs northnortheast north northeast NNE N NE region care 1yearold yearold 1 year old COVID1 COVID- 20 2

Resumo Objetivou-se realizar uma análise espacial da taxa de mortalidade hospitalar (TMH) por síndrome respiratória aguda grave (SRAG) atribuída à COVID-19 em crianças e adolescentes no Brasil no período de 2020 a 2021. Utilizou-se o método de cluster para agrupar as unidades federativas (UFs) com base na TMH. Em 2020, clusters com altas TMHs foram formados por UFs Norte/Nordeste. Em 2021, houve redução na TMH. Os clusters com maiores taxas permaneceram na região N/NE. Diferenças regionais foram observadas nas TMHs. Os achados podem refletir as desigualdades sociais e o acesso à atenção hospitalar, principalmente na faixa etária de menores de 1 ano pela gravidade da doença neste grupo. Objetivouse Objetivou se TMH (TMH SRAG (SRAG COVID19 COVID 19 COVID-1 202 2021 Utilizouse Utilizou (UFs NorteNordeste Norte Nordeste Norte/Nordeste NNE N NE N/NE grupo COVID1 COVID- 20 2

ABSTRACT African mahogany (Khaya grandifoliola) is a tree species that has gained space in the forestry market, presenting utility in a wide range of uses, especially in Brazilian territory, where it is the main substitute for Brazilian mahogany wood. The objective of this work was to perform a path analysis between the response of nutrient solution to cadmium treatment and the other variables and attributes studied: amino acid, nitrate, protein, ammonium, reductase, IDM, cadmium. The experiment was carried out in a greenhouse. At first, seedlings were habituated to be later taken to the treatment, where the applicability was given by cadmium chloride monohydrate (CdCl 2.H2O) according to the nutrient solution. The experimental design was completely randomized (DIC), mixed in five concentrations (0; 10; 20; 30 and 40 mg L-1) with seven replications, totaling 35 experimental units. To perform the comparative examination, the data were exposed to the analysis of variance, followed by regression analysis. The path analysis allowed to directly verify that increasing doses of treatment with Cadmium (CAR) reflected in a negative correlation with the amino acid content (AAR) in the roots of mahogany plants. Abiotic stress, which was exposure to a toxic chemical (cadmium), decreased, in this case, the ability of plants to synthesize amino acids. Increasing doses of cadmium treatment (CAL) reflected in negative correlation with the protein content in the leaf (PRL) of mahogany plants. Evidently, the higher the cadmium concentration, the greater the damage to mahogany's metabolic systems. With this study, we showed that excess cadmium in the soil affects the development of seedlings of forest species such as mahogany. Khaya grandifoliola market uses territory wood studied nitrate ammonium reductase IDM greenhouse first CdCl 2.H2O 2H2O HO 2 H2O H O DIC, DIC , (DIC) 0 (0 10 20 3 4 L1 L 1 L-1 replications units examination variance CAR (CAR AAR (AAR stress cadmium, (cadmium) decreased case acids CAL (CAL PRL (PRL Evidently concentration mahoganys s systems study (DIC ( L- (cadmium

RESUMO O mogno africano (Khaya grandifoliola) é uma espécie arbórea que vem ganhando espaço no mercado florestal, apresentando utilidade nas mais diversas utilizações, principalmente em território brasileiro, onde é o principal substituto da madeira do mogno brasileiro. O objetivo deste trabalho foi realizar uma análise de trilha entre a resposta da solução nutritiva ao tratamento com cádmio e as demais variáveis e atributos estudados: aminoácido, nitrato, proteína, amônio, redutase, IDM, cádmio. O experimento foi conduzido em casa de vegetação. A princípio, as mudas foram habituadas para posteriormente serem levadas ao tratamento, onde a aplicabilidade se deu pelo cloreto de cádmio monohidratado (CdCl 2.H2O) de acordo com a solução nutritiva. O delineamento experimental foi inteiramente casualizado (DIC), misturado em cinco concentrações (0; 10; 20; 30 e 40 mg L-1) com sete repetições, totalizando 35 unidades experimentais. Para realizar o exame comparativo, os dados foram submetidos à análise de variância, seguida de análise de regressão. A análise de trilha permitiu verificar diretamente que doses crescentes de tratamento com Cádmio (CAR) refletiram em correlação negativa com o teor de aminoácidos (TAA) nas raízes das plantas de mogno. O estresse abiótico, que foi a exposição a um produto químico tóxico (cádmio), diminuiu, neste caso, a capacidade das plantas de sintetizar aminoácidos. O aumento das doses de tratamento com cádmio (CAL) refletiu em correlação negativa com o teor de proteína na folha (PRL) das plantas de mogno. Evidentemente, quanto maior a concentração de cádmio, maiores serão os danos aos sistemas metabólicos do mogno. Com este estudo, evidenciamos que excesso de cádmio no solo afeta o desenvolvimento de mudas de espécies florestais como o mogno. Khaya grandifoliola florestal utilizações brasileiro estudados aminoácido nitrato amônio redutase IDM vegetação princípio CdCl 2.H2O 2H2O HO 2 H2O H DIC, DIC , (DIC) 0 (0 10 20 3 4 L1 L 1 L-1 repetições experimentais comparativo variância regressão CAR (CAR TAA (TAA abiótico (cádmio) diminuiu caso CAL (CAL PRL (PRL Evidentemente estudo (DIC ( L- (cádmio

Resumen La religiosidad y la espiritualidad desempeñan un papel clave en la medicina, especialmente en el enfoque centrado en el paciente al mejorar la relación médico-paciente. Muchos médicos aún no utilizan este recurso, debido a la inseguridad a menudo de enfrentar la vida personal de los pacientes. En este estudio se aplicó a 128 médicos y residentes de un hospital universitario de Minas Gerais (Brasil) los cuestionarios Índice de Religiosidad de Duke y Índice de Reactividad Interpersonal Multidimensional entre agosto y diciembre de 2021, así como preguntas planteadas en estudios anteriores sobre salud y espiritualidad. Se pretendió evaluar la percepción de los profesionales sobre la importancia de la religiosidad y la espiritualidad en la práctica clínica y su relación con las actitudes éticas y humanistas. Los resultados revelaron una correlación significativa entre las dos escalas, lo que indica una asociación positiva entre la religiosidad y espiritualidad y la empatía. medicina médicopaciente. médicopaciente médico paciente. médico-paciente recurso pacientes 12 Brasil (Brasil 2021 humanistas escalas empatía 1 202 20 2

Abstract Religiosity and spirituality are pivotal in medical practice, particularly in fostering a patient-centered approach that enhances the physician-patient relationship. Despite this, many physicians still underutilize these invaluable resources, often due to feelings of uncertainty when navigating the personal aspects of patients’ lives. To address this challenge, a survey involving 128 physicians, including residents, was conducted at a university hospital in Minas Gerais between August and December 2021. Utilizing the Duke Religiosity Inventory and Multidimensional Interpersonal Reactivity Scale questionnaires, alongside inquiries drawn from prior studies on health and spirituality, the goal was to assess professionals’ perceptions of the significance of religiosity and spirituality in clinical practice and their interplay with ethical and humanistic attitudes. The findings unveiled a significant correlation between the two scales, underscoring a positive connection between religiosity, spirituality, and empathy. patientcentered patient centered physicianpatient physician relationship resources patients lives challenge 12 residents 2021 questionnaires professionals attitudes scales empathy 1 202 20 2

Resumo A religiosidade e a espiritualidade desempenham papéis cruciais na medicina, especialmente na abordagem centrada no paciente, melhorando a relação médico-paciente. Apesar disso, muitos médicos ainda subutilizam esses recursos, muitas vezes devido a insegurança ao lidar com a esfera pessoal da vida dos pacientes. Para abordar essa questão, conduziu-se pesquisa com 128 médicos, incluindo residentes, em um hospital universitário de Minas Gerais, entre agosto e dezembro de 2021, mediante aplicação dos questionários Inventário de Religiosidade de Duke e Escala Multidimensional de Reatividade Interpessoal, além de questões levantadas em estudos anteriores sobre saúde e espiritualidade. Com isso, buscou-se avaliar de que forma profissionais percebem a importância da religiosidade e da espiritualidade na prática clínica e sua relação com posturas éticas e humanistas. Os resultados revelaram correlação significativa entre as duas escalas, indicando associação positiva entre religiosidade e espiritualidade e empatia. medicina paciente médicopaciente. médicopaciente médico paciente. médico-paciente disso recursos pacientes questão conduziuse conduziu se 12 residentes Gerais 2021 Interpessoal isso buscouse buscou humanistas escalas empatia 1 202 20 2

ABSTRACT Purpose To analyze the effects of auditory stimulation on heart rate variability (HRV) indices in healthy individuals with normal hearing and with hearing loss, regardless of type and/or grade, by means of a systematic review. Research strategies This is a systematic review with a meta-analysis that addresses the following question: in healthy individuals with normal hearing and/or with hearing loss, what are the effects of auditory stimulation on HRV indices in comparison to silence? We consulted the Cochrane Library, Embase, LILACS, PubMed, Web of Science, and Scopus databases and the gray literature (Google Scholar, OpenGrey, and ProQuest). Selection criteria There were no restrictions as to period or language of publication. Data analysis We identified 451 records, an additional 261 in the gray literature, and five studies in a search through the references, resulting in a total of 717 records, with 171 duplicate records. After screening the titles and abstracts of 546 studies, we excluded 490 and considered 56 studies in full to assess their eligibility. Results Nine of these studies were included in the systematic review, eight of which were suitable for the meta-analysis. Conclusion It is suggested that auditory stimulation may influence the RMSSD, pNN50, SDNN, RRTri and SD2 indices of HRV in healthy adults with normal hearing. (HRV loss andor grade metaanalysis meta question silence Library Embase LILACS PubMed Science Google Scholar OpenGrey ProQuest. ProQuest . ProQuest) publication 45 records 26 references 71 17 54 49 5 eligibility metaanalysis. analysis. RMSSD pNN50 pNN SDNN SD 4 2 7 1 pNN5

Investigation of corrosion inhibitors on CO2-saturated aqueous solution with O2 contamination is limited. Hence, this study investigated the corrosion behavior of phosphate ester inhibitor towards carbon steel corrosion in a simulated CO2-O2 environment by potentiodynamic polarization technique and electrochemical impedance spectroscopy. It was shown that the PE prevents the corrosion attack in the presence of CO2-O2, reaching an efficiency of 90.7% with 25 ppm in 3.5 wt% NaCl solution at 25 oC. Furthermore, the superficial characterization of carbon steel was studied by scanning electronic microscopy which supported that the inhibitor protects against corrosion. The varying temperatures showed that PE adsorbed on the steel surface by a physical process and obeyed the Langmuir isotherm. CO2saturated COsaturated CO2 saturated CO O limited Hence CO2O2 COO CO2-O spectroscopy CO2O2, O2, 907 90 7 90.7 2 35 3 5 3. wt oC Furthermore isotherm CO2O 9 90.

Abstract Mortality caused by the COVID-19 pandemic has impacted indicators of Years of Potential Life Lost (YPLL) worldwide. This study aimed to estimate the YPLL due to mortality caused by COVID-19, according to sex, age group, and race/color in Brazil, from March 2020 to December 2021. Deaths caused by COVID-19 were characterized, in which the rates and ratios of standardized YPLL rates, the average number of years of potential life lost (ANYPLL), and the average age at death (AAD) were estimated and compared. Overall, 13,776,969.50 potential years of life were lost, which resulted in an average loss of 22.5 potential years not lived. A greater loss of potential years of life was identified in men (58.12%) and in the age groups from 0 to 59 years in the black (58.92%) and indigenous (63.35%) populations, while in the age groups of 60 years and over, a greater loss of YPLL was observed in the white (45.89%) and yellow (53.22%) populations. Women recorded the highest ADD, with the exception of indigenous women. White men (1.63), brown men (1.59), and black men (1.61) had the highest rates when compared to white women. Although COVID-19 has a greater impact on the elderly, it was the black and indigenous populations under the age of 60 who had the greatest loss of potential years of life.

Resumo A mortalidade provocada pela pandemia da COVID-19 tem produzido impactos aos indicadores de Anos Potenciais de Vida Perdidos (APVP) em nível mundial. Objetiva-se estimar os APVP devido à mortalidade por COVID-19, segundo sexo, faixa etária e raça/cor, no período de março de 2020 a dezembro de 2021, no Brasil. Foram caracterizadas as mortes por COVID-19, estimadas e comparadas as taxas e razão de taxas padronizadas de APVP, a média de anos potenciais de vida não vividos (APVNV) e a idade média do óbito (IMO). No geral, foram perdidos 13.776.969,50 anos potenciais de vida, o que determinou uma perda média de 22,5 anos potenciais não vividos. Houve maior perda de anos potenciais de vida nos homens (58,12%) e nas faixas etárias de 0 a 59 anos nas populações negra (58,92%) e indígena (63,35%), enquanto nas faixas etárias de 60 anos e mais foi observada maior perda de APVP nas populações branca (45,89%) e amarela (53,22%). As mulheres registraram as maiores IMO, com exceção das mulheres indígenas. Homens brancos (1,63), pardos (1,59) e pretos (1,61) tiveram as maiores taxas em comparação às mulheres brancas. Apesar da COVID-19 ter tido maior impacto em idosos, foram as populações negra e indígena na faixa de menos de 60 anos quem teve maior perda de anos potenciais de vida.

Abstract The objective was to perform a spatial analysis of the hospital mortality rate (HMR) due to severe acute respiratory syndrome (SARS) attributed to COVID-19 among children and adolescents in Brazil from 2020 to 2021. A cluster method was used to group federal units (FUs) based on HMR. In 2020, clusters with high HMRs were formed by north/northeast FUs. In 2021, there was a reduction in HMR. Clusters with higher rates remained in the N/NE region. Regional differences were observed in the HMR. The findings may reflect social inequalities and access to hospital care, especially in the under 1-year-old age group due to the severity of the disease in this group.

Resumo Objetivou-se realizar uma análise espacial da taxa de mortalidade hospitalar (TMH) por síndrome respiratória aguda grave (SRAG) atribuída à COVID-19 em crianças e adolescentes no Brasil no período de 2020 a 2021. Utilizou-se o método de cluster para agrupar as unidades federativas (UFs) com base na TMH. Em 2020, clusters com altas TMHs foram formados por UFs Norte/Nordeste. Em 2021, houve redução na TMH. Os clusters com maiores taxas permaneceram na região N/NE. Diferenças regionais foram observadas nas TMHs. Os achados podem refletir as desigualdades sociais e o acesso à atenção hospitalar, principalmente na faixa etária de menores de 1 ano pela gravidade da doença neste grupo.