Abstract Objective: to analyze the association between previous Chikungunya infection and depressive symptoms among healthcare workers. Methods: a cross-sectional study with a probabilistic sample of healthcare workers in primary and medium-complexity care settings in a municipality in the state of Bahia, Brazil. We used the rapid test DPP-ZDC-IgM/IgG to identify recent (IgM) or previous (IgG) Chikungunya virus infection, and the Patient Health Questionnaire-PHQ-9 to assess depressive symptoms. We applied regression with robust variance to estimate prevalence ratios and 95% confidence intervals. Results: 392 workers participated, 83.2% female. The frequency of Chikungunya virus infection was 8.9%. The prevalence of depressive symptoms was 22.7%. In the adjusted analysis, Chikungunya infection was positively associated with depressive symptoms (PR=2.00; 95%CI: 1.29; 3.07). Stratified analyses indicated a stronger association among males (PR=7.57; 95%CI: 1.15; 50.06) compared with females (PR=1.68; 95%CI: 1.03; 2.74). Discussion: the findings support the hypothesis of a positive association between Chikungunya and depressive symptoms. Physiopathological mechanisms resulting from viral action, as well as emotional, behavioral, and psychosocial factors associated with the disease, may explain the findings. We reiterate the importance of providing mental health care to healthcare workers. Objective Methods crosssectional cross sectional mediumcomplexity medium complexity Bahia Brazil DPPZDCIgM/IgG DPPZDCIgMIgG DPP ZDC IgM/IgG IgM IgG (IgM (IgG QuestionnairePHQ9 QuestionnairePHQ Questionnaire PHQ 9 Questionnaire-PHQ- 95 intervals Results 39 participated 832 83 2 83.2 female 89 8 8.9% 227 22 7 22.7% analysis PR=2.00 PR200 PR 00 (PR=2.00 95%CI 95CI CI 1.29 129 1 29 3.07. 307 3.07 . 3 07 3.07) PR=7.57 PR757 57 (PR=7.57 1.15 115 15 50.06 5006 50 06 PR=1.68 PR168 68 (PR=1.68 1.03 103 03 2.74. 274 2.74 74 2.74) Discussion action emotional behavioral disease DPPZDCIgM IgMIgG Questionnaire-PHQ 83. 8.9 22.7 PR=2.0 PR20 0 (PR=2.0 1.2 12 30 3.0 PR=7.5 PR75 5 (PR=7.5 1.1 11 50.0 500 PR=1.6 PR16 6 (PR=1.6 1.0 10 27 2.7 8. 22. PR=2. PR2 (PR=2. 1. 3. PR=7. PR7 (PR=7. 50. PR=1. PR1 (PR=1. 2. PR=2 (PR=2 PR=7 (PR=7 PR=1 (PR=1 PR= (PR= (PR
Resumo Objetivo: analisar a associação entre infecção prévia por Chikungunya e sintomas depressivos em trabalhadores da saúde. Métodos: estudo transversal com amostra probabilística de trabalhadores atuantes na atenção primária e na média complexidade de um município do estado da Bahia, Brasil. Utilizou-se o teste rápido DPP-ZDC-IgM/IgG para identificar infecção recente (IgM) ou prévia (IgG) pelo vírus Chikungunya. O Patient Health Questionnaire-PHQ-9 foi usado para avaliar sintomas depressivos. Regressão de Poisson com variância robusta foi usada para estimar razões de prevalência e intervalos de confiança 95%. Resultados: participaram da pesquisa 392 trabalhadores, sendo 83,2% do sexo feminino. A frequência de infecção pelo vírus Chikungunya foi de 8,9%. A prevalência de sintomas depressivos foi de 22,7%. Na análise ajustada, a infecção por Chikungunya associou-se positivamente aos sintomas depressivos (RP=2,00; IC95%:1,29;3,07). As análises estratificadas apontaram associação de maior magnitude no sexo masculino (RP=7,57;1,15;50,06), em comparação ao feminino (RP=1,68;1,03;2,74). Conclusão: os achados corroboram a hipótese de associação positiva entre Chikungunya e sintomas depressivos. Mecanismos fisiopatológicos decorrentes de ação viral, bem como fatores emocionais, comportamentais e psicossociais associados à doença podem explicar os achados. Reitera-se a importância do cuidado em saúde mental para os trabalhadores da saúde. Objetivo Métodos Bahia Brasil Utilizouse Utilizou se DPPZDCIgM/IgG DPPZDCIgMIgG DPP ZDC IgM/IgG IgM IgG (IgM (IgG QuestionnairePHQ9 QuestionnairePHQ Questionnaire PHQ 9 Questionnaire-PHQ- 95 95% Resultados 39 832 83 2 83,2 89 8 8,9% 227 22 7 22,7% ajustada associouse associou RP=2,00 RP200 RP 00 (RP=2,00 IC95%1,293,07. IC95129307 IC IC95% 1,29 3,07 . IC95 1 29 3 07 IC95%:1,29;3,07) RP=7,571,1550,06, RP7571155006 RP=7,57 1,15 50,06 , 57 15 50 06 (RP=7,57;1,15;50,06) RP=1,681,032,74. RP168103274 RP=1,68 1,03 2,74 68 03 74 (RP=1,68;1,03;2,74) Conclusão viral emocionais Reiterase Reitera DPPZDCIgM IgMIgG Questionnaire-PHQ 83, 8,9 22,7 RP=2,0 RP20 0 (RP=2,0 293 IC95%1,293,07 IC9512930 129 1,2 307 3,0 IC9 IC95%:1,29;3,07 571 1550 RP=7,571,1550,06 RP757115500 RP757 RP=7,5 115 1,1 5006 50,0 5 (RP=7,57;1,15;50,06 681 032 RP=1,681,032,74 RP16810327 RP168 RP=1,6 103 1,0 274 2,7 6 (RP=1,68;1,03;2,74 8, 22, RP=2, RP2 (RP=2, IC95%1,293,0 IC951293 12 1, 30 3, IC95%:1,29;3,0 155 RP=7,571,1550,0 RP75711550 RP75 RP=7, 11 500 50, (RP=7,57;1,15;50,0 RP=1,681,032,7 RP1681032 RP16 RP=1, 10 27 2, (RP=1,68;1,03;2,7 RP=2 (RP=2 IC95%1,293, IC95129 IC95%:1,29;3, RP=7,571,1550, RP7571155 RP7 RP=7 (RP=7,57;1,15;50, RP=1,681,032, RP168103 RP1 RP=1 (RP=1,68;1,03;2, RP= (RP= IC95%1,293 IC9512 IC95%:1,29;3 RP=7,571,1550 RP757115 (RP=7,57;1,15;50 RP=1,681,032 RP16810 (RP=1,68;1,03;2 (RP IC95%1,29 IC951 IC95%:1,29; RP=7,571,155 RP75711 (RP=7,57;1,15;5 RP=1,681,03 RP1681 (RP=1,68;1,03; IC95%1,2 IC95%:1,29 RP=7,571,15 RP7571 (RP=7,57;1,15; RP=1,681,0 (RP=1,68;1,03 IC95%1, IC95%:1,2 RP=7,571,1 (RP=7,57;1,15 RP=1,681, (RP=1,68;1,0 IC95%1 IC95%:1, RP=7,571, (RP=7,57;1,1 RP=1,681 (RP=1,68;1, IC95%:1 RP=7,571 (RP=7,57;1, (RP=1,68;1 IC95%: (RP=7,57;1 (RP=1,68; (RP=7,57; (RP=1,68 (RP=7,57 (RP=1,6 (RP=7,5 (RP=1, (RP=7, (RP=1 (RP=7