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Abstract Reproductive control is one of the biggest challenges in tilapia production and triploidy was developed as an alternative to sterilization. In general, polyploids present chromosomal instability but for triploid Nile tilapia it has yet to be reported. This study evaluated the chromosomal instability from juveniles to adulthood, growth performance and gonadal status of tilapia hatched from eggs submitted or not to heat shock for triploid induction. Nile tilapia oocytes were fertilized (1,476 oocytes), half of the eggs were subjected to a four-minute shock in 41 °C water four minutes after fertilization and the other half were not (Control group). The eggs were incubated (at 27°C) and 160 larvae from the treated group hatched and survived after yolk sac absorption. The determination of ploidy was performed by flow cytometry at 85th (juveniles) and 301st (adults) days of age post yolk sac absorption. At the time of the first cytometry analysis there were 73 surviving juveniles from the treated group, and only 14 were confirmed triploid. However, at the analysis of adult ploidy, one out of 8 surviving adult tilapias from the 14 confirmed triploid juveniles remained triploid. Gonadal histology showed that the non-remaining triploids continued to produce gametes. The growth performance of triploid tilapia was initially superior to that of diploid tilapia during the juvenile phase, but similar in adults. Once the chromosome sets are lost and the tilapias become diploid again, at least in tissues with a high proliferation rate, such as the hematopoietic tissue that was analyzed (and possibly in gonads), all possible advantages of triploids are probably lost. Thus, our results suggest that, due to genomic instabilities, the triploid generation of tilapia has low efficiency. sterilization general reported adulthood induction 1,476 1476 1 476 (1,47 oocytes, , oocytes) fourminute minute 4 C Control group. . group) 27°C 27C 27 16 absorption th (juveniles st adults (adults 7 However nonremaining non remaining gametes phase again rate gonads, gonads gonads) Thus instabilities efficiency 1,47 147 47 (1,4 2 1,4 (1, 1, (1 (

https://doi.org/10.1590/1984-3143-ar2023-0147

Life cycle assessment of minas frescal cheese and cured minas cheese: a comparative analysis
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SILVA, Amanda Almeida da

; ELABRAS-VEIGA, Lilian Bechara

; SOUZA, Simone Lorena Quitério de

; ARAÚJO, Marcelo Guimarães

Food Science and Technology

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2023, Volume 43 elocation e109522

Resumo: En | Texto: En | PDF: En

Abstract Brazil is a large producer of dairy products, with an important role of milk in the country's economy beyond the nutritional aspects. In turn, the dairy industry is associated with environmental impacts, such as water and energy consumption, waste generation, liquid effluents, and atmospheric emissions. Life Cycle Assessment (LCA) is an environmental management tool used to measure the environmental impacts of goods, services, and products. This study used the LCA to assess the impacts resulting from the production of Minas Frescal and cured Minas cheese in an artisanal production facility in Casimiro de Abreu, Rio de Janeiro, Brazil. LCA results showed that the most significant environmental impacts were associated with the dairy farm under study, which is a source of greenhouse gases (GHG) emissions from livestock, particularly methane (CH4), produced through enteric fermentation and manure decomposition, mainly contributing for the impact categories of climate change (31.56%) and human toxicity with carcinogenic effects (35.46%). The cured Minas cheese presented higher impacts when compared to Minas Frescal cheese due to the larger volume of milk used in the manufacturing process. Thus, the present study suggested mitigation measures to lower the environmental impacts based on adjustments in animal feed to reduce atmospheric emissions. products countrys country s aspects turn consumption generation effluents (LCA goods services Abreu Janeiro GHG (GHG livestock CH4, CH4 CH , (CH4) decomposition 31.56% 3156 31 56 (31.56% 35.46%. 3546 35.46% . 35 46 (35.46%) process Thus (CH4 31.56 315 3 5 (31.56 354 35.46 4 (35.46% (CH 31.5 (31.5 35.4 (35.46 31. (31. 35. (35.4 (31 (35. (3 (35 (

https://doi.org/10.1590/fst.109522

COVID-19 outcomes in people living with HIV: Peering through the waves COVID19 COVID 19 COVID-1 HIV COVID1 1 COVID-
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Sales, Thaís Lorenna Souza

; Souza-Silva, Maíra Viana Rego

; Delfino-Pereira, Polianna

; Neves, João Victor Baroni

; Sacioto, Manuela Furtado

; Assis, Vivian Costa Morais de

; Duani, Helena

; Oliveira, Neimy Ramos de

; Sampaio, Natália da Cunha Severino

; Ramos, Lucas Emanuel Ferreira

; Schwarzbold, Alexandre Vargas

; Jorge, Alzira de Oliveira

; Scotton, Ana Luiza Bahia Alves

; Castro, Bruno Mateus de

; Silva, Carla Thais Cândida Alves da

; Ramos, Carolina Marques

; Anschau, Fernando

; Botoni, Fernando Antonio

; Grizende, Genna Maira Santos

; Nascimento, Guilherme Fagundes

; Ruschel, Karen Brasil

; Menezes, Luanna Silva Monteiro

; Castro, Luís César de

; Nasi, Luiz Antônio

; Carneiro, Marcelo

; Godoy, Mariana Frizzo de

; Nogueira, Matheus Carvalho Alves

; Guimarães Júnior, Milton Henriques

; Ziegelmann, Patricia Klarmann

; Almeida, Rafaela Charão de

; Francisco, Saionara Cristina

; Silveira Neto, Sidney Teodoro

; Araújo, Silvia Ferreira

; Avelino-Silva, Thiago Junqueira

; Aliberti, Márlon Juliano Romero

; Pires, Magda Carvalho

; Silva, Eduardo Sérgio da

; Marcolino, Milena Soriano

Clinics

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2023, Volume 78 elocation 100223

Resumo: En | Texto: En | PDF: En

Abstract Objective To evaluate clinical characteristics and outcomes of COVID-19 patients infected with HIV, and to compare with a paired sample without HIV infection. Methods This is a substudy of a Brazilian multicentric cohort that comprised two periods (2020 and 2021). Data was obtained through the retrospective review of medical records. Primary outcomes were admission to the intensive care unit, invasive mechanical ventilation, and death. Patients with HIV and controls were matched for age, sex, number of comorbidities, and hospital of origin using the technique of propensity score matching (up to 4:1). They were compared using the Chi-Square or Fisher's Exact tests for categorical variables and the Wilcoxon for numerical variables. Results Throughout the study, 17,101 COVID-19 patients were hospitalized, and 130 (0.76%) of those were infected with HIV. The median age was 54 (IQR: 43.0;64.0) years in 2020 and 53 (IQR: 46.0;63.5) years in 2021, with a predominance of females in both periods. People Living with HIV (PLHIV) and their controls showed similar prevalence for admission to the ICU and invasive mechanical ventilation requirement in the two periods, with no significant differences. In 2020, in-hospital mortality was higher in the PLHIV compared to the controls (27.9% vs. 17.7%; p = 0.049), but there was no difference in mortality between groups in 2021 (25.0% vs. 25.1%; p > 0.999). Conclusions Our results reiterate that PLHIV were at higher risk of COVID-19 mortality in the early stages of the pandemic, however, this finding did not sustain in 2021, when the mortality rate is similar to the control group. COVID19 COVID 19 COVID-1 infection (202 2021. . 2021) records unit death sex comorbidities up 41. 41 4 1 4:1) ChiSquare Chi Square Fishers Fisher s study 17101 17 101 17,10 hospitalized 13 0.76% 076 0 76 (0.76% 5 IQR (IQR 43.064.0 430640 43.0 64.0 43 64 43.0;64.0 202 46.063.5 460635 46.0 63.5 46 63 46.0;63.5 (PLHIV differences inhospital 27.9% 279 27 9 (27.9 vs 17.7% 177 7 0.049, 0049 0.049 , 049 0.049) 25.0% 250 25 (25.0 25.1% 251 0.999. 0999 0.999 999 0.999) pandemic however group COVID1 COVID- (20 4:1 1710 10 17,1 0.76 07 (0.76 064 43.064. 43064 430 43. 640 64. 6 43.0;64. 20 063 46.063. 46063 460 46. 635 63. 46.0;63. 27.9 2 (27. 17.7 004 0.04 04 25.0 (25. 25.1 099 0.99 99 (2 4: 171 17, 0.7 (0.7 06 43.064 4306 43.0;64 46.063 4606 46.0;63 27. (27 17. 00 0.0 25. (25 09 0.9 ( 0. (0. 43.06 43.0;6 46.06 46.0;6 (0 43.0; 46.0;

https://doi.org/10.1016/j.clinsp.2023.100223

A scoping review about LGBTQIAP+ people in oral health research LGBTQIAP
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SILVA, Eliane Maria Mascarenhas da

; FÉLIX, Thallys Rodrigues

; BÖNECKER, Marcelo

; ZINA, Lívia Guimarães

; DRUMMOND, Andreia Maria Araújo

; MATTOS, Flávio Freitas

Brazilian Oral Research

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2023, Volume 37 elocation e125

Resumo: En | Texto: En | PDF: En

Abstract Oral health personnel must acknowledge the health needs of sexual and gender minorities. They should consult scientific literature to deepen their knowledge about sexuality, gender identity, general and oral health status, and treatment disparities among LGBTQIA+ people. The aim of this scoping review was to portray the development and current stage of internationally indexed literature approaching the oral health of this population. In this study, the search strategy used consisted of combinations of subject descriptors (MeSH terms), in two concept blocks: LGBTQIAP+ people and oral health. Global literature was searched through Medline (PUBMED), Web of Science, Embase, Lilacs, and Scopus electronic databases, with no language or date restrictions. Records were selected and evaluated by two independent reviewers, under the supervision of three senior reviewers and the inclusion criteria resulted in 189 eligible papers. Since the first study was published in 1974, numbers increased over the decades, reaching 67 (35.4%) in 2010-2019. The most frequently studied populations were North American (42.9%) and European (19.0%) and the most frequent language of publication was English (99.0%). There were 38 open access papers (20.1%). Medical (57.7%) and dental journals (20.1%) predominated. Cross-sectional studies were found more frequently (65.1%), followed by the cohort type (11.1%). Oral manifestation of STI (58.7%) was the topic most frequently addressed. The search for literature approaching the oral health of LGBTQIAP+ people showed evidence of the need to encourage research reported in papers made easily available, with more robust scientific evidence, and on a broader scope of topics, including oral health needs and treatment, and planning of oral health services. minorities sexuality identity status LGBTQIA population MeSH terms, terms , terms) blocks LGBTQIAP PUBMED, PUBMED (PUBMED) Science Embase Lilacs databases restrictions 18 1974 decades 6 35.4% 354 35 4 (35.4% 20102019. 20102019 2010 2019. 2019 2010-2019 42.9% 429 42 9 (42.9% 19.0% 190 19 0 (19.0% 99.0%. 990 99.0% . 99 (99.0%) 3 20.1%. 201 20.1% 20 1 57.7% 577 57 7 (57.7% (20.1% predominated Crosssectional Cross sectional 65.1%, 651 65.1% 65 (65.1%) 11.1%. 111 11.1% 11 (11.1%) 58.7% 587 58 (58.7% addressed available topics services (PUBMED 197 35.4 (35.4 2010201 2010-201 42.9 (42.9 19.0 (19.0 99.0 (99.0% 20.1 2 57.7 5 (57.7 (20.1 65.1 (65.1% 11.1 (11.1% 58.7 (58.7 35. (35. 201020 2010-20 42. (42. 19. (19. 99. (99.0 20. 57. (57. (20. 65. (65.1 11. (11.1 58. (58. (35 20102 2010-2 (42 (19 (99. (57 (20 (65. (11. (58 (3 2010- (4 (1 (99 (5 (2 (65 (11 ( (9 (6

https://doi.org/10.1590/1807-3107bor-2023.vol37.0125

Saúde pública, ciência e sociedade: desafios e perspectivas
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Costa, Nilson do Rosário

; Cardoso, Gisela Cordeiro Pereira

; Castro, Hermano Albuquerque de

; Araújo, Marcelo Guimarães

; Moreira, Maria de Fátima

Saúde em Debate

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Dez 2021, Volume 45 Nº spe2 Páginas 4 - 9

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/0103-11042021e200

Chronic use of hydroxychloroquine did not protect against COVID-19 in a large cohort of patients with rheumatic diseases in Brazil
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Pileggi, Gecilmara Salviato

; Ferreira, Gilda Aparecida

; Gomides Reis, Ana Paula Monteiro

; Reis Neto, Edgard Torres

; Abreu, Mirhelen Mendes

; Albuquerque, Cleandro Pires

; Araújo, Nafice Costa

; Bacchiega, Ana Beatriz

; Bianchi, Dante Valdetaro

; Bica, Blanca

; Bonfa, Eloisa Duarte

; Borba, Eduardo Ferreira

; Brito, Danielle Christinne Soares Egypto

; Duarte, Ângela Luzia Branco Pinto

; Santo, Rafaela Cavalheiro Espírito

; Fernandes, Paula Reale

; Guimarães, Mariana Peixoto

; Gomes, Kirla Wagner Poti

; Kakehasi, Adriana Maria

; Klumb, Evandro Mendes

; Lanna, Cristina Costa Duarte

; Marques, Claudia Diniz Lopes

; Monticielo, Odirlei André

; Mota, Licia Maria Henrique

; Munhoz, Gabriela Araújo

; Paiva, Eduardo Santos

; Pereira, Helena Lucia Alves

; Provenza, José Roberto

; Ribeiro, Sandra Lucia Euzébio

; Rocha Junior, Laurindo Ferreira

; Sampaio, Camila Santana Justo Cintra

; Sampaio, Vanderson Souza

; Sato, Emília Inoue

; Skare, Thelma

; de Souza, Viviane Angelina

; Valim, Valeria

; Lacerda, Marcus Vinícius Guimarães

; Xavier, Ricardo Machado

; Pinheiro, Marcelo Medeiros

Advances in Rheumatology

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2021, Volume 61 elocation 60

Resumo: En | Texto: En | PDF: En

Abstract Background: There is a lack of information on the role of chronic use of hydroxychloroquine during the SARS-CoV-2 outbreak. Our aim was to compare the occurrence of COVID-19 between rheumatic disease patients on hydroxychloroquine with individuals from the same household not taking the drug during the first 8 weeks of community viral transmission in Brazil. Methods: This baseline cross-sectional analysis is part of a 24-week observational multi-center study involving 22 Brazilian academic outpatient centers. All information regarding COVID-19 symptoms, epidemiological, clinical, and demographic data were recorded on a specific web-based platform using telephone calls from physicians and medical students. COVID-19 was defined according to the Brazilian Ministry of Health (BMH) criteria. Mann-Whitney, Chi-square and Exact Fisher tests were used for statistical analysis and two binary Final Logistic Regression Model by Wald test were developed using a backward-stepwise method for the presence of COVID-19. Results: From March 29th to May 17st, 2020, a total of 10,443 participants were enrolled, including 5166 (53.9%) rheumatic disease patients, of whom 82.5% had systemic erythematosus lupus, 7.8% rheumatoid arthritis, 3.7% Sjögren’s syndrome and 0.8% systemic sclerosis. In total, 1822 (19.1%) participants reported flu symptoms within the 30 days prior to enrollment, of which 3.1% fulfilled the BMH criteria, but with no significant difference between rheumatic disease patients (4.03%) and controls (3.25%). After adjustments for multiple confounders, the main risk factor significantly associated with a COVID-19 diagnosis was lung disease (OR 1.63; 95% CI 1.03-2.58); and for rheumatic disease patients were diagnosis of systemic sclerosis (OR 2.8; 95% CI 1.19-6.63) and glucocorticoids above 10 mg/ day (OR 2.05; 95% CI 1.31-3.19). In addition, a recent influenza vaccination had a protective effect (OR 0.674; 95% CI 0.46-0.98). Conclusion: Patients with rheumatic disease on hydroxychloroquine presented a similar occurrence of COVID-19 to household cohabitants, suggesting a lack of any protective role against SARS-CoV-2 infection. Trial registration Brazilian Registry of Clinical Trials (ReBEC; RBR - 9KTWX6).

https://doi.org/10.1186/s42358-021-00217-0 22 downloads

Pathological findings and morphologic correlation of the lungs of autopsied patients with SARS-CoV-2 infection in the Brazilian Amazon using transmission electron microscopy
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Santana, Monique Freire

; Pinto, Rebecca Augusta de Araújo

; Marcon, Bruna Hilzendeger

; Medeiros, Lia Carolina Almeida Soares de

; Morais, Thiago Barros do Nascimento de

; Dias, Lucas Castanhola

; Souza, Lorenna Pereira de

; Melo, Gisely Cardoso de

; Monteiro, Wuelton Marcelo

; Lacerda, Marcus Vinicius Guimarães

; Val, Fernando Almeida

; Lalwani, Pritesh Jaychand

; Ferreira, Luiz Carlos de Lima

Revista da Sociedade Brasileira de Medicina Tropical

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2021, Volume 54 elocation e0850-2020

Resumo: En | Texto: En | PDF: En

Abstract INTRODUCTION: Electron microscopy (EM) is a rapid and effective tool that can be used to create images of a whole spectrum of virus-host interactions and, as such, has long been used in the discovery and description of viral mechanisms. METHODS: Electron microscopy was used to evaluate the pulmonary pathologies of postmortem lung sections from three patients who died from infection with SARS-associated coronavirus 2 (SARS-CoV-2), a new member of the Coronaviridae family. RESULTS: Diffuse alveolar damage (DAD) was predominant in all three patients. The early exudative stage was characterized principally by edema and extravasation of red blood cells into the alveolar space with injury to the alveolar epithelial cells; this was followed by detachment, apoptosis, and necrosis of type I and II pneumocytes. The capillaries exhibited congestion, exposure of the basement membrane from denuded endothelial cells, platelet adhesion, fibrin thrombi, and rupture of the capillary walls. The proliferative stage was characterized by pronounced proliferation of type II alveolar pneumocytes and multinucleated giant cells. The cytopathic effect of SARS-CoV-2 was observed both in degenerated type II pneumocytes and freely circulating in the alveoli, with components from virions, macrophages, lymphocytes, and cellular debris. CONCLUSIONS: Viral particles consistent with the characteristics of SARS-CoV-2 were observed mainly in degenerated pneumocytes, in the endothelium, or freely circulating in the alveoli. In the final stage of illness, the alveolar spaces were replaced by fibrosis.

https://doi.org/10.1590/0037-8682-0850-2020 1013 downloads

Saúde pública, ciência e sociedade: desafios e perspectivas
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Costa, Nilson do Rosário

; Cardoso, Gisela Cordeiro Pereira

; Castro, Hermano Albuquerque de

; Araújo, Marcelo Guimarães

; Moreira, Maria de Fátima

Saúde em Debate

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2021, Volume 45 Nº spe2 Páginas 4 - 9

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/0103-11042021e200

Agronomic performance of arugula/nira intercropping in different cultivation arrangements
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Guimarães, Marcelo de Almeida

; Lima Neto, Benedito Pereira

; Lemos Neto, Hozano de Souza

; Hendges, Ana Régia Alves de Araújo

; Viana, Caris dos Santos

; Rabelo, Janiquelle da Silva

Horticultura Brasileira

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Set 2020, Volume 38 Nº 3 Páginas 329 - 333

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO O planejamento espacial dos arranjos de cultivo é fundamental para garantir a superioridade do consórcio em relação ao monocultivo. Assim, objetivou-se avaliar o desempenho agronômico do consórcio rúcula e nirá em diferentes arranjos de cultivo. O experimento foi conduzido no delineamento em blocos casualizados, em esquema de parcela subdividida, com as parcelas sendo os arranjos de cultivo e as subparcelas os ciclos de produção (inverno e primavera). Os arranjos foram T1= monocultivo de rúcula; T2= duas linhas de rúcula alternadas com três de nirá (2R:3N); T3= duas linhas de rúcula alternadas com duas de nirá (2R:2N); T4= duas linhas de rúcula alternadas com uma de nirá (2R:1N); T5= monocultivo de nirá. Foram avaliadas as características produtivas e os índices de desempenho agronômico dos consórcios. A rúcula solteira e o cultivo consorciado 2R:1N alcançaram produtividade semelhante, porém o cultivo consorciado 2R:1N foi o que apresentou maior eficiência produtiva, com uso eficiente da terra (UET) de 1,16%, tendo a rúcula uma contribuição relativa de 84,3% no rendimento produtivo do sistema. O cultivo consorciado 2R:1N pode ser utilizado para a maior otimização no uso dos insumos produtivos em cultivo de rúcula.

ABSTRACT Spatial planning of cultivation arrangements is essential to ensure the superiority of intercropping when compared with monocrop. Thus, the aim of this study was to evaluate the agronomic performance of arugula/nira intercropping in different cultivation arrangements. The experiment was carried out in a randomized block design, in a split plot scheme, the plots represented the cultivation arrangements and the subplots the production cycles (winter and spring). The arrangements were T1= arugula monoculture; T2= two rows of arugula alternating with three rows of nira (2R:3N); T3= two rows of arugula alternating with two rows of nira (2R:2N); T4= two rows of arugula alternating with one row of nira (2R:1N); T5= nira monoculture. Productive traits and agronomic performance indexes of the intercropping systems were evaluated. Single arugula cultivation and 2R:1N intercropping achieved similar productivity, 2R:1N intercropping showed the highest productive efficiency, with land-use efficiency of 1.16%, though arugula showed a relative contribution of 84.3% in production yield of the system. We concluded that 2R:1N intercropping can be used to optimize the use of productive inputs in arugula cultivation.

https://doi.org/10.1590/s0102-053620200315 802 downloads

10.

Determination of TNF-a Gene Polymorphisms on Skeletal Pattern in Class II Malocclusion
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Levy, Simone Carvalho

; Antunes, Lívia Azeredo Alves

; Abreu, Julia Guimaraes Barcellos de

; Nascimento, Jullia Assis da Silva

; Kuntz, Ana Carolina

; Fialho, Walter Luis Soares

; Rodrigues, Amanda Silva

; Teixeira, Ellen Cardoso

; Calasans-Maia, José de Albuquerque

; Araújo, Marcelo Calvo de

; Küchler, Erika C.

; Antunes, Leonardo Santos

Brazilian Dental Journal

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Mar 2019, Volume 30 Nº 2 Páginas 152 - 156

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo O desenvolvimento e crescimento ósseo é um processo contínuo, que dura toda a vida, variando muito entre os indivíduos e grande parte dessa variação pode ser modulada por fatores genéticos. O objetivo deste estudo foi avaliar a associação entre os polimorfismos no gene TNF-a e a má oclusão da classe II esquelética. Polimorfismos no gene TNF-a (rs1799724; rs1800629) foram estudados em 79 indivíduos com má oclusão esquelética de classe II e 102 indivíduos com má oclusão esquelética classe I do Grupo de Estudos em Ortodontia e Ortopedia Funcional dos Maxilares do Rio de Janeiro, Brasil. A genotipagem destes polimorfismos foi realizada por PCR em tempo real, através de DNA genômico extraído de células bucais. Todas as frequências alélicas e genotípicas foram comparadas entre os grupos utilizando o software PLINK® em um modelo livre, dominante e recessivo. Foi aplicado o teste do qui-quadrado (p≤0,05). Não houve associação significativa na distribuição genotipica e alélica do gene TNF-a (rs1799724; rs1800629) com a má oclusão de classe II esquelética. Independentemente do modelo genético dominante ou recessivo, as associações genotípicas preferenciais para rs1799724 e rs1800629 foram insignificantes. Pode-se concluir que, não existe evidência de associação entre polimorfismos genéticos envolvendo TNF-a e má oclusão esquelética de classe II ou a posição da maxila e mandíbula na direção póstero-anterior.

Abstract Bone development and growth is a non-going, life-long process, varying greatly among individuals and much of this variation could be modulated by genetic factors. The purpose of this study was to evaluate the association between the polymorphisms in the TNF-a gene and skeletal class II malocclusion. Single nucleotide polymorphisms in TNF-a (rs1799724; rs1800629) gene were studied in 79 skeletal class II malocclusion and 102 skeletal class I malocclusion subjects from Straight Wire Group of Studies on Orthodontics and Functional Orthopedics for Maxillary from Rio de Janeiro, Brazil. The Genotyping of these selected polymorphisms was carried out by TaqMan real-time PCR using genomic DNA extracted from buccal cells. All allele and genotype frequencies were compared between the groups using the PLINK® software in a free, in a dominant and in a recessive model using a chi-square test (p≤0.05). There was no significant association of TNF-a (rs1799724; rs1800629) genotype and allele distribution with skeletal class II malocclusion. Regardless of the dominant or recessive genetic model, the preferential genotype associations for rs1799724 and rs1800629 was insignificant. In conclusion, no evidence of association is apparent between genetic polymorphisms involving TNF-a and skeletal class II malocclusion or the position of the maxilla and mandible in the postero-anterior direction.

https://doi.org/10.1590/0103-6440201902367 1268 downloads

11.

Could Plasmodium vivax malaria trigger malnutrition? Revisiting the Bradford Hill criteria to assess a causal relationship between two neglected problems
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Monteiro, Wuelton Marcelo

; Alexandre, Márcia Araújo

; Siqueira, André

; Melo, Gisely

; Romero, Gustavo Adolfo Sierra

; d'Ávila, Efrem

; Benzecry, Silvana Gomes

; Leite, Heitor Pons

; Lacerda, Marcus Vinícius Guimarães

Revista da Sociedade Brasileira de Medicina Tropical

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Jun 2016, Volume 49 Nº 3 Páginas 274 - 278

Resumo: En | Texto: En | PDF: En

Abstract: The benign characteristics formerly attributed to Plasmodium vivax infections have recently changed owing to the increasing number of reports of severe vivax malaria resulting in a broad spectrum of clinical complications, probably including undernutrition. Causal inference is a complex process, and arriving at a tentative inference of the causal or non-causal nature of an association is a subjective process limited by the existing evidence. Applying classical epidemiology principles, such as the Bradford Hill criteria, may help foster an understanding of causality and lead to appropriate interventions being proposed that may improve quality of life and decrease morbidity in neglected populations. Here, we examined these criteria in the context of the available data suggesting that vivax malaria may substantially contribute to childhood malnutrition. We found the data supported a role for P. vivax in the etiology of undernutrition in endemic areas. Thus, the application of modern causal inference tools, in future studies, may be useful in determining causation.

https://doi.org/10.1590/0037-8682-0397-2015 2061 downloads

12.

We need to talk more about transfusion-transmitted malaria in Plasmodium vivax endemic areas
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Lacerda, Marcus Vinícius Guimarães

; Monteiro, Wuelton Marcelo

; Alexandre, Márcia Almeida Araújo

; Alho, Regina Rebouças Mendes

; Kiesslich, Dagmar

; Fraiji, Nelson Abrahim

Revista Brasileira de Hematologia e Hemoterapia

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Dez 2014, Volume 36 Nº 6 Páginas 385 - 387

Resumo: En | Texto: En | PDF: En

https://doi.org/10.1016/j.bjhh.2014.09.005 874 downloads

13.

A MÚSICA PODE SER UMA ESTRATÉGIA PARA O ENSINO DE CIÊNCIAS NATURAIS? ANALISANDO CONCEPÇÕES DE PROFESSORES DA EDUCAÇÃO BÁSICA.
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Barros, Marcelo Diniz Monteiro de

; Zanella, Priscilla Guimarães

; Araújo-Jorge, Tania Cremonini de

Ensaio Pesquisa em Educação em Ciências (Belo Horizonte)

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Abr 2013, Volume 15 Nº 1 Páginas 81 - 94

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

O presente trabalho apresenta uma investigação dos possíveis usos da música popular brasileira por professores das disciplinas de Ciências Naturais e Biologia, e foi realizado em escolas de educação básica. A pesquisa foi do tipo descritiva, de campo, mista, e utilizou o questionário como instrumento de coleta de dados. As informações obtidas no questionário demonstraram que a maioria dos professores utiliza com baixa frequência ou não utiliza a música popular brasileira como estratégia para o ensino dessas disciplinas. Foram discutidas as opiniões dos professores, ligando-as aos principais fatores que poderiam contribuir para aqueles resultados, bem como todos os motivos que levam os professores a utilizar ou não essa estratégia pedagógica.

The present work has as its goal the research on the possible uses of Brazilian Popular Music by teachers of Natural Sciences and Biology, and it was undertook in basic education schools. The research was descriptive, field made, also mixing and using the questionnaire to collect data. Information obtained by the questionnaire showed that most teachers almost never or do not use at all, Brazilian Popular Music as a strategy for teaching Natural Sciences or Biology. The teacher's opinions were also heard and all these key factors that could contribute to those results were gathered, exploring all the reasons that can make teachers use or not this teaching strategy.

https://doi.org/10.1590/1983-21172013150106 16413 downloads

14.

Identification of occlusal prematurity by clinical examination and cone-beam computed tomography
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Machado, Naila Aparecida de Godoi

; Henriques, João César Guimarães

; Lelis, Éverton Ribeiro

; Tavares, Marcelo

; Almeida, Guilherme de Araújo

; Fernandes Neto, Alfredo Júlio

Brazilian Dental Journal

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2013, Volume 24 Nº 1 Páginas 64 - 67

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

O objetivo deste estudo foi avaliar a capacidade de identificação de prematuridades oclusais por meio de imagens obtidas de cortes paraxiais de tomografias computadorizadas de feixe cônico. Para este fim, realizou-se um estudo piloto em que 16 pacientes jovens assintomáticos foram submetidos ao exame clínico, incluindo análise oclusal criteriosa, e em seguida foram confeccionados dispositivos desprogramadores individuais (“JIG de Lucia”). Mediante manipulação mandibular e marcação interoclusal com papel carbono (Accufilm) identificou-se clinicamente o contato prematuro em relação cêntrica (RC) de cada paciente. Posteriormente estes dispositivos foram ajustados na posição de contato cêntrico e utilizados durante os exames tomográficos para que se pudessem obter imagens tomográficas na posição de relação cêntrica. Após o processamento das imagens, estas foram analisadas com o intuito de identificar prematuridades oclusais nas imagens visualizadas por 30 profissionais divididos de acordo com as áreas de atuação (Oclusão, Clínica Geral e Radiologia, n=10 para cada área) e tempo de exercício profissional (<5; entre 5 e 10; e >10 anos). Mediante comparação entre os contatos prematuros identificados na análise clínica oclusal e as imagens tomográficas apontadas pelos profissionais como áreas de contatos prematuros, foram calculados os índices de concordância entre essas duas variáveis. Os dados obtidos foram analisados estatisticamente pela Análise de Variância ANOVA e teste de Scott-Knott (α=0,05). Os resultados deste estudo demonstraram que a identificação de prematuridades oclusais por meio de cortes paraxiais de tomografias computadorizadas de feixe cônico mostrou-se como um método de confiabilidade média.

The aim of this study was to evaluate the ability to identify occlusal prematurity by images from paraxial slices of cone-beam computed tomography (CBCT). For such purpose, a pilot study was performed in which 16 asymptomatic young patients were subjected to a clinical examination, including a careful occlusal analysis and then individual deprogrammer devices (“Lucia's JIG”) were fabricated. Premature contacts were clinically identified in centric relation (CR) for each patient by jaw manipulation and interocclusal marking with articulating paper (Accufilm). Subsequently, these devices were adjusted in CR and used during the tomographic exams in such a way that CBCT in CR could be obtained. After routine processing, the images were analyzed in order to identify occlusal prematurity on the displayed images by 30 professionals divided according to areas of activity (occlusion specialist, general practitioner and radiologist; n=10 per area) and time of professional experience (less than 5, between 5 and 10, and over 10 years). By comparing the premature contacts identified in the clinical analysis and CBCT images, an agreement index between these two variables was calculated. Data were analyzed statistically by ANOVA and Scott-Knott test (α=0.05). The results showed that the identification of occlusal prematurity by paraxial CBCT slices was proven to be a method of average reliability.

https://doi.org/10.1590/0103-6440201301974 5338 downloads

15.

Disposição do nematóide Bursaphelenchus cocophilus (Cobb) baujard, em coqueiros portadores da doença anel-vermelho
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Duarte, Adriana Guimarães

; Lima, Ivanildo Soares de

; Araújo Júnior, Josemildo Verçosa de

; Duarte, Alexandre Guimarães

; Albuquerque, Ariane Loudemila Silva de

; Cruz, Marcelo de Menezes

Revista Brasileira de Fruticultura

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Set 2008, Volume 30 Nº 3 Páginas 622 - 627

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Este trabalho teve o objetivo de conhecer como o nematóide Bursaphelenchus cocophilus tende a se distribuir no interior das plantas de coqueiros em estágios avançados da doença anel-vermelho. Nas amostras de raízes coletadas junto à base da estipe de coqueiros doentes, o número de nematóides foi consideravelmente maior que encontrado em raízes situadas entre um e três metros de distância da estipe. Observou-se que, à medida que se afasta da estipe, a possibilidade de encontrar nematóides na raiz é mínima, de forma que as chances de transmissão da doença, de uma planta para outra, através das raízes, devem ser muito pequenas. Na região do palmito, onde o tecido é mais tenro, é possível encontrar o nematóide tanto nas áreas avermelhadas quanto nas áreas aparentemente sadias. Nos tecidos do pecíolo, foram encontrados nematóides em pequena quantidade. Portanto, práticas profiláticas, visando à desinfecção do facão utilizado na colheita e despalma, devem ser realizadas com a finalidade de eliminar a transmissão da doença. Nenhuma das amostras obtidas dos tecidos da ráquis e dos folíolos estava contaminada. A população de nematóide é mais alta nos excrementos de túneis larvais das regiões apicais do coqueiro, o que confere maior chance de serem transportados para outras plantas, aderidos ao corpo do seu principal vetor, os adultos de Rhynchophorus palmarum.

The aim of this work was to investigate how the nematode Bursaphelenchus cocophilus tends to distribute itself inside the coconut palm trees in advanced stages of the red ring disease. In the samples of the roots collected at the base of the stem of sick trees, the number of nematodes was considerably higher when compared to the number found in the roots situated between one and three meters away from the stem. It was observed that, as it stands back of the sick plant, the possibility to find nematodes in the root is remote, so that the chances of transmission of the disease, from one plant to another, by means of the roots are minimal. At the top part of the stem, where the tissue is softer, it is possible to find the nematode both in the discolored areas and in the adjacent tissues, apparently healthy. In the tissues of the petioles, nematodes were found in small amounts. Therefore, the practice of the scythe disinfections used in the harvesting and leaf pruning should be recommended with the purpose of decreasing the possibility of transmission of the disease. None of the obtained samples from tissues of the rachis and leaves were contaminated. The population of nematode is higher in the excrements of larval tunnels of the apical parts of the plant, which provide higher chances of being transported, from one plant to another, stuck on to the body of its main vector, the coconut palm weevil Rhynchophorus palmarum.

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