Pesquisa | SciELO

Abstract To date, hydroxyurea is the only effective and safe drug that significantly reduces morbidity and mortality of individuals with Sickle cell disease. Twenty years of real-life experience has demonstrated that hydroxyurea reduces pain attacks, vaso-occlusive events, including acute chest syndrome, the number and duration of hospitalizations and the need for transfusion. The therapeutic success of hydroxyurea is directly linked to access to the drug, the dose used and adherence to treatment which, in part, is correlated to the availability of hydroxyurea. This consensus aims to reduce the number of mandatory exams needed to access the drug, prioritizing the requesting physician's report, without affecting patient safety. date disease reallife real life attacks vasoocclusive vaso occlusive events syndrome transfusion which part physicians physician s report safety

https://doi.org/10.1016/j.htct.2024.01.001

Screening for myeloid mutations in patients with myelodysplastic syndromes and AML with myelodysplasia-related changes
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Bezerra, Matheus F.

; Larrazábal, Bruna R.

; Lima, Aleide S.

; Mello, Mariana R.

; Pimentel, Raphael F.

; Weinhäuser, Isabel

; Costa, Fernando F.

; Fertrin, Kleber Y.

; Araújo, Aderson S.

; Machado, Cíntia G.

; Bezerra, Marcos A.

; Lucena-Araujo, Antonio R.

Hematology, Transfusion and Cell Therapy

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Set 2022, Volume 44 Nº 3 Páginas 328 - 331

Resumo: En | Texto: En | PDF: En

ABSTRACT Introduction: One of the most critical complications in myelodysplastic syndromes (MDS) is the progression to acute myeloid leukemia (AML). The dynamics of clonal evolution in MDS and how acquired mutations can be used as biomarkers to track disease progression remains under investigation. Objective and method: Herein, we investigated the frequency of common myeloid clonal mutations (FLT3, NPM1, JAK2, IDH1 and IDH2) in 88 patients with MDS and 35 AML patients with myelodysplasia-related changes, followed at a single reference center in northeastern Brazil. Results: Overall, 9/88 (10%) ofthe MDSpatients and 9/35 (26%) of the secondary AML patients had at least one mutation. While the JAK2 V617F mutation was the most frequent in the MDS patients, the FLT3, NPM1, IDH1 and IDH2 mutations were more frequently found in the secondary AML group. Furthermore, there was a higher frequency of FLT3, NPM1, IDH1 and IDH2 mutations in MDS patients classified as high-risk subtypes than in those of lower risk. Conclusion: Despite the limited sample size, our data suggest that mutations in FLT3, NPM1, IDH1 and IDH2 genes could be potential biomarkers to detect early disease progression in MDS.

https://doi.org/10.1016/j.htct.2020.10.967

Association of HMIP1 C-893A polymorphism and disease severity in patients with sickle cell anemia
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Pereira-Martins, Diego A

; Domingos, Igor F

; Belini-Junior, Edis

; Coelho-Silva, Juan L

; Weinhäuser, Isabel

; Araújo, Aderson S

; Lobo, Clarisse L

; Bonini-Domingos, Claudia R

; Bezerra, Marcos A

; Lucena-Araujo, Antonio R

Hematology, Transfusion and Cell Therapy

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Set 2021, Volume 43 Nº 3 Páginas 243 - 248

Resumo: En | Texto: En | PDF: En

Abstract Introduction: Sickle cell anemia (SCA) is a Mendelian disorder with a heterogeneous clinical course. The reasons for this phenotypic diversity are not entirely established, but it is known that high fetal hemoglobin levels lead to a milder course of the disease. Additionally, genetic variants in the intergenic region HBS1L-MYB promote high levels of fetal hemoglobin into adulthood. Objective: In the present study, we investigated the HMIP1 C-839A (rs9376092) polymorphism, located at the HBS1L-MYB intergenic region block 1, in SCA patients. Method: We analyzed 299 SCA patients followed in two reference centers in Brazil. The HMIP1 C-839A (rs9376092) genotypes were determined by allele specific polymerase chain reactions. Clinical and laboratory data were obtained from patient interviews and medical records. Results: The median fetal hemoglobin levels were higher in patients with the HMIP1 C-839A (rs9376092) AA genotype (CC = 6.4%, CA = 5.6% and AA = 8.6%), but this difference did not reach significance (p = 0.194). No association between HMIP1 C-839A (rs9376092) genotypes and other clinical and laboratorial features was detected (p > 0.05). Conclusion: In summary, our data could not support the previously related association between the HMIP1 C-893A (rs9376092) polymorphism and differential fetal hemoglobin levels.

https://doi.org/10.1016/j.htct.2020.03.006 17 downloads

Consensus statement for diagnosis and treatment of paroxysmal nocturnal haemoglobinuria
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Cançado, Rodolfo D

; Araújo, Aderson da Silva

; Sandes, Alex Freire

; Arrais, Celso

; Lobo, Clarisse Lopes de Castro

; Figueiredo, Maria Stella

; Gualandro, Sandra Fátima Menosi

; Saad, Sara Teresinha Olalla

; Costa, Fernando Ferreira

Hematology, Transfusion and Cell Therapy

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Set 2021, Volume 43 Nº 3 Páginas 341 - 348

Resumo: En | Texto: En | PDF: En

Paroxysmal nocturnal hemoglobinuria is a chronic, multi-systemic, progressive and lifethreatening disease characterized by intravascular hemolysis, thrombotic events, serious infections and bone marrow failure. Paroxysmal nocturnal hemoglobinuria results from the expansion of a clone of hematopoietic cells that due to an inactivating mutation of the X-linked gene PIG-A are deficient in glycosylphosphatidylinositol-linked proteins. Early diagnosis, using flow cytometry performed on peripheral blood, the gold standard test to confirm the diagnosis of paroxysmal nocturnal hemoglobinuria, is essential for improved patient management and prognosis. The traditional therapy for paroxysmal nocturnal hemoglobinuria includes blood transfusion, anti-thrombosis prophylaxis or allogeneic bone marrow transplantation. The treatment that has recently become available is the complement blockade by the anti-C5 monoclonal antibody eculizumab. In this consensus, we are aiming to review the diagnosis and treatment of the paroxysmal nocturnal hemoglobinuria patients, as well as the early recognition of its systemic complications. These procedures express the opinions of experts and have been based on the best available evidence and international guidelines, with the purpose of increasing benefits and reducing harm to patients.

https://doi.org/10.1016/j.htct.2020.06.006 23 downloads

Polymorphisms in the heme oxygenase-1 and bone morphogenetic protein receptor type 1b genes and estimated glomerular filtration rate in Brazilian sickle cell anemia patients
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Chinedu, Okeke

; Tonassé, Wouitchékpo Vincent

; Albuquerque, Dulcinéia Martins

; Domingos, Igor de Farias

; Araújo, Aderson da Silva

; Bezerra, Marcos André Cavalcanti

; Sonati, Maria de Fátima

; Santos, Magnun Nueldo Nunes dos

Hematology, Transfusion and Cell Therapy

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Jun 2021, Volume 43 Nº 2 Páginas 165 - 170

Resumo: En | Texto: En | PDF: En

ABSTRACT Introduction Mutations affecting genes involved in oxidative and signaling pathways may be associated with kidney disease in sickle cell anemia. We determined the allele and genotype frequencies of some polymorphisms in the promoter regions of the Heme Oxygenase-1 (HMOX1) [rs2071746 (A > T) and (GT)n repeats, short (S) and long (L) alleles] and Bone Morphogenetic Protein Receptor type-1B (BMPR1B) [rs17022863 (A > G), rs4331783 (A > G) and rs1470409 (A > G)] genes in 75 adult patients with sickle cell anemia and 160 healthy controls and investigated whether these polymorphisms may influence the estimated glomerular filtration rate for the patients. Methods The single nucleotide polymorphisms were genotyped using the TaqMan assays, the HMOX1(GT)n repeats were determined by polymerase chain reaction fragment size analysis and the estimated glomerular filtration rate was calculated by the Modification of Diet in Renal Disease formula. Results Regarding the HMOX1rs2071746, the estimated glomerular filtration rate median was significantly higher in TT patients (p = 0.019), including when TT was compared with AT + AA (p = 0.009); for the (GT)n repeats, the estimated glomerular filtration rate medians of SS, SL and LL significantly differed (p = 0.009), being the LL estimated glomerular filtration rate median significantly higher, when compared with the LS + SS (p = 0.005). These results suggest that both the homozygotes, TT for rs2071746 and LL for (GT)n repeats, lead to a higher risk of developing renal complications. Concerning the BMPR1B, the frequencies of GG for rs17022863 and AA for rs4331783 were significantly higher in patients than in controls (p = 0.002 and p = 0.008, respectively), however no association with estimated glomerular filtration rate was found. Conclusion These results contribute to a better understanding of the genetic factors related to the development of nephropathy in sickle cell anemia patients.

https://doi.org/10.1016/j.htct.2020.01.009 82 downloads

Soil water dynamics and yield in maize and Brachiaria ruziziensis intercropping
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Silva, Gabriela Sabrine França

; Andrade Júnior, Aderson Soares de

; Cardoso, Milton José

; Araújo Neto, Raimundo Bezerra de

Pesquisa Agropecuária Tropical

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2020, Volume 50 elocation e59809

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO Em cultivos consorciados, uma alta densidade de plantas pode retardar o acúmulo de biomassa e afetar a disponibilidade hídrica às plantas. Objetivou-se avaliar a dinâmica da água no solo e o desempenho produtivo no consórcio de milho e Brachiaria ruziziensis sob diferentes densidades de semeadura desta forrageira. O experimento foi conduzido em blocos casualizados, com tratamentos associados às densidades de semeadura (2 kg ha-1, 4 kg ha-1, 6 kg ha-1 e 8 kg ha-1) e ambas as espécies em monocultivo como testemunhas. No milho, avaliou-se a produtividade de grãos e, na braquiária, o número de plantas por hectare e as massas verde e seca da parte aérea. O desempenho do consórcio foi avaliado pelo índice de uso eficiente da terra. A dinâmica da água no solo foi monitorada em duas profundidades (0-0,3 m e 0,3-0,6 m), pela técnica de reflectometria no domínio do tempo. A avaliação do armazenamento de água no solo foi realizada a partir de parcelas com quatro dos sistemas de cultivo (milho ou braquiária em monocultivo, e consórcios com as densidades de semeadura extremas), em quatro períodos. O aumento na densidade de semeadura de B. ruziziensis diminuiu a produtividade dos grãos do milho consorciado em 30,8 %. O consórcio usando 2 kg ha-1 de sementes da forrageira proporcionou melhor eficiência no uso da terra (23 %). Ademais, os tratamentos com consórcio promoveram maior extração de água do solo, especialmente nas fases de maior exigência hídrica do milho (e.g., florescimento e enchimento de grãos). Estes sistemas simulam a extração de água em maiores profundidades, quando comparados ao milho em cultivo solteiro.

ABSTRACT In intercropping systems, a high plant density can delay the biomass accumulation and affect the water availability to plants. This study aimed to evaluate the soil water dynamics and the crop yield performance in maize and Brachiaria ruziziensis intercropping under different sowing densities of the forage grass. The experiment was conducted in a randomized block design, with treatments associated to the sowing densities (2 kg ha-1, 4 kg ha-1, 6 kg ha-1 and 8 kg ha-1) and the single cropping for both species as controls. The maize plants were evaluated for grain yield and B. ruziziensis for number of plants per hectare and shoot fresh and dry matter. The intercropping performance was evaluated using the land-use efficiency index. The soil water dynamics was monitored in two soil depths (0-0.3 m and 0.3-0.6 m) by using the time domain reflectometry method. The evaluation of soil water storage was carried out from plots with four of the crop systems (single maize or B. ruziziensis, and intercropping with the extreme sowing densities), at four different times. The increase in the sowing density of B. ruziziensis decreased the grain yield of the intercropped maize by 30.8 %. The intercropping system using 2 kg ha-1 of the grass seeds resulted in the best land-use efficiency (23 %). In addition, the intercropping treatments promoted a higher extraction of water from the soil, mainly at the maize growth stages with higher hydric demand (e.g., flowering and grain filling). These systems stimulate the extraction of water from deeper soil layers, when compared to maize in single cropping.

https://doi.org/10.1590/1983-40632020v5059809 725 downloads

Interleukin-6 in pregnancy with sickle cell disease
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Costa, Manuela Freire Hazin

; Torres, Leuridan Cavalcante

; Matta, Marina Cadena da

; Araújo, Aderson da Silva

; Souza, Ariani Impieri

Hematology, Transfusion and Cell Therapy

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Dez 2019, Volume 41 Nº 4 Páginas 298 - 302

Resumo: En | Texto: En | PDF: En

ABSTRACT Background: Despite advances in health care for sickle cell disease patients, as well as in the improvement in reproductive issues mainly in women with the disease, pregnancy is still a challenge, both for the mother and the child, with high rates of maternal and fetal morbidity and mortality. Besides their chronic hemolytic status and vaso-occlusive events that confer systemic complications, pregnant women also have higher rates of pain episodes, infections, abortion, intrauterine growth retardation, pre-term births, eclampsia, stillbirth and the hemolysis, elevated liver enzymes and low platelets syndrome. The physiologic mechanisms of the disease in pregnancy are still unknown and chronic inflammatory responses may interfere in the adverse outcomes. The cytokine and chemokine profiles in pregnancy with sickle cell disease remain unknown. The aim of this study was to evaluate the cytokine profile of the inflammatory response of pregnant women with sickle cell disease. Method: Blood samples from 20 pregnant women with sickle cell disease, 24 women with sickle cell disease in steady state, 16 healthy pregnant women and a control group with 9 women at childbearing age were assayed for interleukin-6. Main results: Pregnant women with sickle cell disease presented high serum levels of interleukin-6, compared to healthy pregnant women (p = 0.0115). Conclusion: These data suggest that the increased production of interleukin-6 may occur during pregnancy with sickle cell disease and that the role of this cytokine in the sickle cell disease pathophysiology and pregnancy complications should be further studied.

https://doi.org/10.1016/j.htct.2019.02.001 354 downloads

Combined genotypes of the MBL2 gene related to low mannose-binding lectin levels are associated with vaso-occlusive events in children with sickle cell anemia
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Medeiros, Fernanda Silva

; Mendonça, Taciana Furtado de

; Lopes, Katiuscia Araújo de Miranda

; França, Laís Medeiros da Câmara

; Silva, Andreia Soares da

; Vasconcelos, Luydson Richardson Silva

; Oliveira, Maria do Carmo Valgueiro Costa de

; Anjos, Ana Cláudia Mendonça dos

; Hatzlhofer, Betânia Lucena Domingues

; Bezerra, Marcos André Cavalcanti

; Araújo, Aderson da Silva

; Moura, Patrícia

; Cavalcanti, Maria do Socorro de Mendonça

Genetics and Molecular Biology

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Set 2017, Volume 40 Nº 3 Páginas 600 - 603

Resumo: En | Texto: En | PDF: En

Abstract Sickle cell anemia (SCA) presents heterogenous clinical manifestations that cannot be explained solely by alterations to hemoglobin (Hb); other components such as endothelial adhesion, thrombosis and inflammation may be involved. The mannose-binding lectin (MBL) has an important role in innate immunity and inflammatory diseases. In this report, we describe an association between MBL2 polymorphism related to low production of serum MBL and the frequency of vasoocclusive events (FVOE) in children ≤ 5 years old with SCA (p = 0.0229; OR 5.55; CI 1.11-27.66). Further studies are needed to explore the role of low MBL2 in the pathophysiology of vasoocclusive events in SCA.

https://doi.org/10.1590/1678-4685-gmb-2016-0161 792 downloads

Qualidade física e composição química de sementes de Foeniculum vulgare
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Neto, Aderson C. Araujo

; Medeiros, José G. F.

; Araújo, Paulo C.

; Bruno, Riselane de L. A.

; Silva, Katiane da R. G. da

Revista de Ciências Agrárias

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Mar 2015, Volume 38 Nº 1 Páginas 94 - 102

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

A erva-doce (Foeniculum vulgare), pertencente à família Apiaceae, apresenta propriedades aromáticas, condimentares e medicinais, podendo ser usada como medicamento natural e na indústria de cosméticos. No entanto, a sua produção está sendo inviabilizada em função do ataque do pulgão Hiadaphis foeniculi, que ataca principalmente a inflorescência da planta, sugando a seiva e depauperando as sementes. Assim, os objetivos deste estudo consistiram em avaliar a qualidade física e a composição química de sementes de erva-doce oriundas de plantas atacadas e não atacadas por Hiadaphis foeniculi. Utilizaram-se cinco lotes de sementes colhidos separadamente por tratamentos em campo experimental no município de Lagoa Seca, PB. O delineamento inteiramente casualizado, consistia em quatro repetições, em esquema fatorial (2 x 5), sendo dois tratamentos em campo (sementes oriundas de plantas atacadas ou não pelo pulgão) e cinco lotes de sementes. Avaliaram-se as seguintes variáveis: teor de água, peso de mil sementes, número de sementes por quilograma, biometria (comprimento, espessura e largura) e os teores de lipídios totais e proteína bruta. O ataque do pulgão comprometeu significativamente a qualidade física e a composição química das sementes de erva-doce, reduzindo, principalmente, o peso, o tamanho e o teor de óleo.

The fennel (Foeniculum vulgare), belongs to the Apiaceae family, has aromatic, condiments and medicinal properties and can be used in natural medicine and cosmetic industry. However, its production is being unviable due to the attack of the aphids species Hiadaphis foeniculi, which mainly attacks the inflorescence of the plant, sucking sap and depleting the seeds. The objectives of this study were to evaluate the physical quality and chemical composition of fennel seeds produced by plants attacked and not attacked by Hiadaphis foeniculi. Five lots of seeds harvested separately by treatments in an experimental field in Lagoa Seca-PB were used. The experimental design was completely randomized with four replications in a factorial (2 x 5), two treatments in the field (seeds produced by plants attacked by aphids or not) and five seed lots. The following variables were evaluated: water content, thousand seed weight, number of seeds per kilogram, biometry (length, width and thickness) and the contents of total lipids and crude protein. The attack of aphids significantly compromised the physical quality and chemical composition of the seeds of fennel, reducing mainly the weight, size and oil content.

2340 downloads

10.

Guidelines on the treatment of anemia of chronic renal failure using recombinant human erythropoietin: Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular Guidelines Project: Associação Médica Brasileira – 2014
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Araújo, Aderson da Silva

; Lobo, Clarisse Lopes de Castro

; Covas, Dimas Tadeu

; Costa, Fernando Ferreira

; Medeiros, Letícia

; Cançado, Rodolfo Delfini

; Gualandro, Sandra Fátima Menosi

; Saad, Sara Teresinha Olalla

Revista Brasileira de Hematologia e Hemoterapia

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Dez 2014, Volume 36 Nº 6 Páginas 450 - 453

Resumo: En | Texto: En | PDF: En

https://doi.org/10.1016/j.bjhh.2014.09.009 1896 downloads

11.

Follow-up of children with hemoglobinopathies diagnosed by the Brazilian Neonatal Screening Program in the State of Pernambuco
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Soares, Ana Caroline Novaes

; Samico, Isabella Chagas

; Araújo, Aderson Silva

; Bezerra, Marcos André C.

; Hatzlhofer, Betânia Lucena Domingues

Revista Brasileira de Hematologia e Hemoterapia

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Ago 2014, Volume 36 Nº 4 Páginas 250 - 255

Resumo: En | Texto: En | PDF: En

OBJECTIVE: To determine the geographical distribution of hemoglobinopathies in the State of Pernambuco, to characterize the children with these diseases and to describe factors associated with their follow-up at the referral center during the period from 2003 to 2010.METHODS: A retrospective, cross-sectional, descriptive study was carried out of 275 medical records from a total of 302 children with hemoglobinopathies diagnosed by the National Neonatal Screening Program in the State of Pernambuco in the study period. Microsoft Excel was used for data processing and analysis. The chi-square and the Fisher test were used for statistical analysis. The level of significance was set at 5%. Terra View software was used to analyze the geographical distribution of hemoglobinopathies in the State.RESULTS: A total of 8.9% of the cases of hemoglobinopathies detected in the period were not followed up at the referral center. For the mothers of children with diseases, this was their second or third or more pregnancy in 64.2% and 30.2%, respectively. Regarding the influence of region of residence and regular medical appointments, the study demonstrated that children from the Zona da Mata, Sertão and Vale do São Francisco regions did not attend 45.2%, 50% and 55.6% of their appointments in the outpatient department, respectively.CONCLUSIONS: This study shows that a significant number of children do not begin consultations in the outpatient clinic and even those who started treatment early and who have the most severe form of the disease, usually miss medical appointments.

https://doi.org/10.1016/j.bjhh.2014.05.001 1320 downloads

12.

Playful intervention with chronically-ill children: promoting coping
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Moura, Flávia Moura de

; Costa Júnior, Áderson Luiz

; Dantas, Meryeli Santos de Araújo

; Araújo, Gilvan da Cruz Barbosa

; Collet, Neusa

Revista Gaúcha de Enfermagem

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Jun 2014, Volume 35 Nº 2 Páginas 86 - 92

Resumo: Pt En Es | Texto: Pt En Es | PDF: Pt | PDF: En | PDF: Es

As doenças crônicas podem gerar consequências adversas ao processo de desenvolvimento infantil. O estudo teve por objetivo analisar os efeitos da realização de atividades do manual "Como Hóspede no Hospital" sobre o processo de enfrentamento de crianças afetadas por doenças crônicas. Pesquisa qualitativa do tipo pesquisa-ação. Participaram do estudo seis crianças e adolescentes, entre 7 e 13 anos, com doenças crônicas. Os dados foram coletados na clínica pediátrica de um hospital público do estado da Paraíba, por meio de observações participantes e sessões individuais com a aplicação de atividades do manual. A interpretação dos dados seguiu os princípios da análise temática. As atividades do manual estimularam a busca de informação sobre a doença e o tratamento, e aumentaram o interesse e a participação das crianças e dos adolescentes em envolver-se no cuidado à saúde, contribuindo para um melhor enfrentamento. Aponta-se a necessidade de cuidados integrais às crianças com doenças crônicas.

Chronic diseases can adversely affect the development process of children. This qualitative, action-research study had the aim to analyze the effects of activities in the manual "Como Hóspede no Hospital" (As a patient in the hospital) on the coping process of children with chronic diseases. Study participants included six children and adolescents aged seven to 13 years, who suffered from a chronic disease. Data were collected in the pediatric clinic of a public hospital in the Brazilian state of Paraíba, through participant observation and individual sessions with activities from the manual. Data interpretation followed the principles of thematic analysis. The activities from the manual encouraged participants' search for information about their disease and treatment, and increased their interest and participation in their health care process, thereby contributing to better coping. The study points to the need for comprehensive care for children with chronic diseases.

Las enfermedades crónicas pueden tener consecuencias adversas para el proceso de desarrollo del niño. El estudio tuvo como objetivo analizar los efectos de la realización de actividades del guía "Cómo huésped en el Hospital" en el proceso de enfrentamiento de los niños afectados por enfermedades crónicas. Investigación cualitativa del tipo investigación-acción. El estudio incluyó a seis niños y adolescentes de 7 a 13 años con enfermedades crónicas. Los datos fueron recogidos en la clínica pediátrica de un hospital público en el estado de Paraíba a través de la observación participante y sesiones individuales con la aplicación de las actividades del guía. La interpretación de los datos siguió los principios de análisis temático. Las actividades del guía alientan la búsqueda de información sobre la enfermedad y el tratamiento y aumentaron el interés y la participación de los niños y adolescentes en involucrarse en el cuidado de la salud, lo que contribuye a un mejor enfrentamiento. Se señala la necesidad de una atención integral a los niños con enfermedades crónicas.

https://doi.org/10.1590/1983-1447.2014.02.41822 4012 downloads

13.

Playful intervention with chronically-ill children: promoting coping
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Moura, Flávia Moura de

; Costa Júnior, Áderson Luiz

; Dantas, Meryeli Santos de Araújo

; Araújo, Gilvan da Cruz Barbosa

; Collet, Neusa

Revista Gaúcha de Enfermagem

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Jun 2014, Volume 35 Nº 2 Páginas 86 - 92

Resumo: En Es Pt | Texto: En Es Pt | PDF: En | PDF: Es | PDF: Pt

https://doi.org/10.1590/1983-1447.2014.02.41822 3 downloads

14.

Preparação psicológica de pacientes submetidos a procedimentos cirúrgicos
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Costa Junior, Áderson Luiz

; Doca, Fernanda Nascimento Pereira

; Araújo, Ivy

; Martins, Luciana

; Mundim, Lara

; Penatti, Ticiana

; Sidrim, Ana Cristina

Estudos de Psicologia (Campinas)

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Jun 2012, Volume 29 Nº 2 Páginas 271 - 284

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Este trabalho tem por objetivo identificar, entre artigos publicados em periódicos indexados pelo PubMed/MedLine, informações sobre as principais modalidades e efeitos de intervenção psicossocial em procedimentos pré e pós-operatórios com pacientes adultos, bem como, apontar algumas lacunas na produção científica acerca do tema. Foram selecionados 32 artigos, sendo oito teórico-conceituais e 24 empíricos, dos quais um era estudo de caso, nove se referiam à avaliação específica de efeitos de preparação psicológica e 14 tratavam de temas associados ao contexto de preparação psicológica e cuidados cirúrgicos. As intervenções psicológicas foram divididas em oito categorias, baseadas em características funcionais das respectivas intervenções. Verificou-se uma deficiência de estudos na área de atuação específica da Psicologia, sendo os profissionais de enfermagem e medicina os que mais produziram estudos sobre o tema. Constatou-se, também, a ausência de protocolos sistematizados de intervenção psicológica relacionados a procedimentos cirúrgicos.

This paper aims to identify information on the main types and effects of psychosocial intervention in pre- and post-operative adult patients in articles published in journals indexed by PubMed/MedLine. It also highlights gaps in scientific literature on the subject. We selected 32 articles: eight theoretical and 24 empirical. One of these was a case study; nine referred to the evaluation of the effects of psychological preparation; and 14 dealt with issues related to the context of psychological preparation and surgical care. Psychological interventions were divided into eight general categories, based on functional characteristics. We discovered an absence of research in the field of psychology on the subject, with the nursing and medical professions providing more material for study. We also noted an absence of systematised psychological intervention protocols related to surgical procedures.

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Araújo, Adérson

Revista Brasileira de Hematologia e Hemoterapia

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2010, Volume 32 Nº 5 Páginas 347 - 347

Resumo: Pt | Texto: Pt | PDF: Pt

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