Abstract Introduction Gender inequality occurs in all spheres of society, which is no different in the medical field. Abstract presentations in congress are the vanguard of scientific knowledge, an integral part of topic discussion, and, ideally, culminate in the publication of these works as complete manuscripts. Objective The objective of this study is to evaluate the role played by women in the presentation of scientific works at the Brazilian Society of Coloproctology congress and in the works published from these presentations. Methods The bibliometric evaluation of the presented abstracts in the editions from 2015 to 2018 of the Brazilian Congress of Coloproctology was used, along with the works later published from these presentations. Gender identification data was extracted from the authors of the abstracts through their names and research for conference on the Lattes and Google Scholar platforms. The collected data was on the number of female participants and their order of authorship of abstracts and publications, evaluating possible changes when publication occurs. Results Atotal of 1,336 abstracts were analyzed, with 91.6% of female authors. When publication occurs, women’s presence dropped to 75.2% and suffered a change of order in the position of authorship to one of lesser relevance in 38.1%. Conclusion Women’s participation occurs in most abstracts. However, this proportion undergoes unfavorable changes when these works are published, either by changing the order of authorship, when women leave main positions and become coauthors, or are removed from the complete manuscript’s publication. society field knowledge discussion ideally manuscripts 201 used platforms publications 1336 1 336 1,33 analyzed 916 91 6 91.6 womens s 752 75 2 75.2 381 38 38.1% Womens Women However coauthors manuscript 20 133 33 1,3 9 91. 7 75. 3 38.1 13 1, 38.

RESUMO RACIONAL: O megaesôfago avançado predispõe riscos clínicos de desnutrição, infecções e neoplasias, além de impacto significativo na qualidade de vida. Não há um consenso atual na literatura ante a melhor opção de seu tratamento cirúrgico, embora haja predileção pela esofagectomia, cirurgia de significativa morbimortalidade associada. Outras modalidades cirúrgicas têm sido propostas, com bons resultados, como a mucosectomia esofágica e a cardiomiotomia laparoscópica à Heller. OBJETIVOS: Realizar uma revisão sistemática com metanálise da literatura acerca do tratamento cirúrgico do megaesôfago avançado. MÉTODOS: As bases de dados utilizadas foram PubMed, Lilacs, Embase e MedLine, além de pesquisas de referências relacionadas. Os artigos foram selecionados por dois revisores independentemente. RESULTADOS: Foram selecionados 14 artigos, que incluem 1.862 pacientes. Os estudos foram divididos em dois grupos: cardiomiotomia laparoscópica com fundoplicatura (213 pacientes) e cirurgias de grande porte (1.649 pacientes). Os estudos analisados evidenciam que ambos os grupos apresentaram resultados semelhantes quanto ao desfecho tardio, considerado majoritariamente bom ou excelente, no entanto, houve significativa morbimortalidade associada ao grupo de cirurgias maiores. CONCLUSÕES: A cardiomiotomia laparoscópica com fundoplicatura pode ser realizada no megaesôfago avançado, com taxas de complicações e mortalidade reduzidas frente às cirurgias de grande porte, porém, com ressalvas quanto ao desfecho tardio a longo prazo. RACIONAL desnutrição neoplasias vida esofagectomia propostas Heller OBJETIVOS MÉTODOS PubMed Lilacs MedLine relacionadas independentemente RESULTADOS 1 1862 862 1.86 pacientes 213 (21 1.649 1649 649 (1.64 . excelente entanto maiores CONCLUSÕES porém prazo 186 86 1.8 21 (2 1.64 164 64 (1.6 18 8 1. 2 ( 1.6 16 6 (1. (1

ABSTRACT BACKGROUND: Advanced megaesophagus predisposes to risks of malnutrition infections and cancer, in addition to having a significant impact on quality of life. There is currently no consensus in the literature regarding the best surgical option for advanced megaesophagus, although there is a predilection for esophagectomy, despite this surgery being associated with significant morbidity and mortality. Other surgical procedures, such as esophageal mucosectomy and Heller cardiomyotomy, have been proposed with good results. AIMS: To conduct a systematic review and meta-analysis of the literature on the surgical treatment of advanced megaesophagus. METHODS: Databases used included PubMed, Latin American and Caribbean Health Sciences Literature (Lilacs), Embase and Medical Literature Analysis and Retrieval System Online (MedLine), as well as reference research. Two reviewers selected the articles independently. RESULTS: A total of 14 articles were chosen, which included 1,862 patients. The studies were divided into two groups: laparoscopic cardiomyotomy with fundoplication (213 patients) and major surgeries (1,649 patients). The studies yielded mostly good or excellent results regarding late outcomes in both groups. However, there was significant morbidity associated with the major surgeries group. CONCLUSIONS: Laparoscopic Heller myotomy can be performed on patients with advanced megaesophagus, with lower rates of complications and mortality compared to major surgeries, with reservations regarding late outcomes results. BACKGROUND cancer life esophagectomy procedures AIMS metaanalysis meta analysis METHODS PubMed Lilacs, Lilacs , (Lilacs) MedLine, MedLine (MedLine) research independently RESULTS 1 chosen 1862 862 1,86 groups 213 (21 1,649 1649 649 (1,64 . However group CONCLUSIONS (Lilacs (MedLine 186 86 1,8 21 (2 1,64 164 64 (1,6 18 8 1, 2 ( 1,6 16 6 (1, (1

Abstract Introduction Scientific studies in Brazil grew around 10.7% compared to previous years. However, the level of quality of evidence has been decreasing. The aim in our study is to examine the meeting abstracts of the Brazilian congress of coloproctology and analyze the level of evidence in trends and variables. Methods A descriptive bibliometric study, working with secondary data to review scientific abstracts in the annals of the coloproctology congress from 2015 to 2019. Results A total of 1756 abstracts of the Brazilian Congress of Coloproctology were analyzed for 5 years (2015-2019). There was a higher trend of abstracts presented with lower levels of evidence (level of evidence 5: 52.3% and 3: 30%), being the majority composed of case reports (49.4%) and retrospective studies (30.4%). The last two years analyzed (2018: 55.2% and 2019: 59.3%) had a predominance above average of case reports. From 2017 to 2019 there was a significant decrease in the number of level 2 evidence studies (18.10%,11.80% and 5.50%), while the number of studies with level 5 evidence showed an increase (45.60%, 56.60% and 61.40%). Statistical analysis occurred in only 17%, with an important decrease for the last two years (2018: 13.6%; 2019: 12.1%). Conclusions Although the data of this study is from the Brazilian coloproctology point of view, they are important for the global scientific community, as they allow a quantitative evaluation of the relative contribution from the level of evidence of Brazilian coloproctology researchers to the scientific scenario. 107 10 7 10.7 However decreasing variables 201 175 20152019. 20152019 . (2015-2019) 523 52 3 52.3 30%, 30 30% , 30%) 49.4% 494 49 4 (49.4% 30.4%. 304 30.4% (30.4%) 2018 (2018 552 55 55.2 59.3% 593 59 18.10%,11.80% 18101180 18 11 80 (18.10%,11.80 5.50%, 550 5.50% 50 5.50%) 45.60%, 4560 45 60 (45.60% 5660 56 56.60 61.40%. 6140 61.40% 61 40 61.40%) 17 17% 13.6% 136 13 6 12.1%. 121 12.1% 12 1 12.1%) view community scenario 10. 20 2015201 (2015-2019 52. 49.4 (49.4 30.4 (30.4% (201 55. 59.3 18.10%,11.80 1810118 8 (18.10%,11.8 5.50 45.60% 456 (45.60 566 56.6 614 61.40 13.6 12.1 201520 (2015-201 49. (49. 30. (30.4 (20 59. 18.10%,11.8 181011 (18.10%,11. 5.5 45.60 (45.6 56. 61.4 13. 12. 20152 (2015-20 (49 (30. (2 18.10%,11. 18101 (18.10%,11 5. 45.6 (45. 61. (2015-2 (4 (30 ( 18.10%,11 1810 (18.10%,1 45. (45 (2015- (3 18.10%,1 181 (18.10%, (2015 18.10%, (18.10% 18.10% (18.10 18.10 (18.1 18.1 (18. 18. (18 (1

ABSTRACT Introduction The purpose of this retrospective bibliometric study was to assess the discrepancies between coloproctology surgery meeting abstracts and subsequent full-length manuscript publications. Methods Abstracts presented at the Brazilian Congress of Coloproctology Surgery from 2015 to 2019 were compared with matching manuscript publications. Discrepancies between the abstract and therefore the subsequent manuscript were categorized as major (changes within the purpose, methods, study design, sample size, statistical analysis, results, and conclusions) and minor (changes within the title, authorship, and number of female authors) variations. Results The conversion rate of abstracts in published manuscripts was 6,9% (121 abstracts). There were inconsistencies between the study title (66,1%), authorship (69,5%), study design (3,3%), sample size (39,2%), statistical analysis (24,8%), results (25,6%), and conclusions (12,4%) of manuscripts compared with their corresponding meeting abstracts. Conclusion As changes occur before manuscript publication of coloproctology surgery meeting abstracts, caution should be exercised in referencing abstracts or altering surgical practices based on abstracts content. fulllength full length publications 201 methods authors variations 69 6 9 6,9 121 (12 . abstracts) 66,1%, 661 66,1% , 66 1 (66,1%) 69,5%, 695 69,5% 5 (69,5%) 3,3%, 33 3,3% 3 (3,3%) 39,2%, 392 39,2% 39 2 (39,2%) 24,8%, 248 24,8% 24 8 (24,8%) 25,6%, 256 25,6% 25 (25,6%) 12,4% 124 12 4 (12,4% content 20 6, (1 66,1 (66,1% 69,5 (69,5% 3,3 (3,3% 39,2 (39,2% 24,8 (24,8% 25,6 (25,6% 12,4 (12,4 ( 66, (66,1 69, (69,5 3, (3,3 39, (39,2 24, (24,8 25, (25,6 12, (12, (66, (69, (3, (39, (24, (25, (66 (69 (3 (39 (24 (25 (6 (2

Abstract Introduction The presentation of abstracts in a congress is an important step for the dissemination of scientific information. The American Congress of Coloproctology is promoted by the American Society of Colon & Rectal Surgeons (ASCRS), and it is the largest in number of participants within the specialty, followed by the Brazilian Congress of Coloproctology. The present study aims to evaluate variables related to the quality of the scientific production of the abstracts presented in these two events and their conversion rate to published manuscripts. Materials and Methods The present bibliometric study assesses secondary data from the review of abstracts presented in these 2 important conferences in 2016, followed by a research of the publications from these congress presentations. Results The total number of abstracts evaluated was 854. The rate of articles containing statistical analyses was of 73.7% in the American congress, and of 34.1% in the Brazilian congress. Multicentric studies were more prevalent in the American congress (23.1%). Regarding study design, the most common were case reports in the Brazilian (44.8%) congress and retrospective studies in the American congress (67.7%). As for the works presented, the rate of conversion into full manuscripts in the American congress was of 24.2% compared with 10.6% in the Brazilian congress. Most papers from the American congress (93.7%) have citations compared with 68.6% of the other event evaluated. Conclusion The scientific performance demonstrated by the conversion rate of abstracts into publications is below ideal, mainly in relation to the Brazilian meeting; yet, there were significant differences between the two events in terms of the profile of the presentations and several variables analyzed. information ASCRS, ASCRS , (ASCRS) specialty 2016 854 737 73 7 73.7 341 34 1 34.1 23.1%. 231 23.1% . 23 (23.1%) design 44.8% 448 44 8 (44.8% 67.7%. 677 67.7% 67 (67.7%) 242 24 24.2 106 10 6 10.6 93.7% 937 93 (93.7% 686 68 68.6 ideal meeting yet analyzed (ASCRS 201 85 73. 3 34. 23.1 (23.1% 44.8 4 (44.8 67.7 (67.7% 24. 10. 93.7 9 (93.7 68. 20 23. (23.1 44. (44. 67. (67.7 93. (93. (23. (44 (67. (93 (23 (4 (67 (9 (2 ( (6

ABSTRACT Introduction: the presentation of research at a congress is an interesting means for scientific dissemination, but only with publication in an indexed journal does the data become accessible and disseminated. The conversion rate in published articles of abstracts presented at congresses is an indicator to assess the scientific quality of those events. The aim of this study is to evaluate bibliometric characteristics of abstracts presented at the Brazilian Congress of Coloproctology and to determine the factors that affect publication rates. Methods: Retrospective evaluation of all abstracts presented at the Brazilian Congresses of Coloproctology from 2015 to 2019. Multiple databases were analyzed to estimate the conversion rate of the presented papers, as well as variables associated with the conversion of abstracts into full manuscripts through bivariate analysis and multivariate variables of these predictors. Results: 1756 abstracts were analyzed. Most studies are retrospective, series or case reports, and even personal experience. The conversion rate was 6.9%. The presence of statistical analysis was twice as high for published abstracts as for unpublished ones. Conclusion: the data presented demonstrate a low scientific productivity of the specialty, since the research carried out is, for the most part, not published as complete manuscripts. The predictors of publication of abstracts were: multicenter studies, studies with statistical analysis, study designs with a higher level of evidence and studies awarded by the congress. Introduction dissemination disseminated events rates Methods 201 2019 papers Results 175 retrospective reports experience 69 6 9 6.9% ones Conclusion specialty part 20 17 6.9 2 1 6.

RESUMO Introdução: a apresentação de pesquisas em um congresso é meio interessante para disseminação científica, porém apenas com a publicação em revista indexada é que os dados se tornam acessíveis e disseminados. A taxa de conversão em artigos publicados de resumos apresentados em congressos é um indicador para avaliar a qualidade científica de seus eventos. O objetivo deste estudo é avaliar características bibliométricas dos resumos apresentados no Congresso Brasileiro de Coloproctologia e determinar os fatores que afetam as taxas de publicação. Métodos: avaliação retrospectiva de todos os resumos apresentados nos Congressos Brasileiros de Coloproctologia dos anos de 2015 a 2019. Análise de múltiplas bases de dados para estimar a taxa de conversão dos trabalhos apresentados, assim como variáveis associadas à conversão dos resumos em manuscritos completos através de análises bivariadas e multivariadas desses preditores. Resultados: foram analisados 1756 resumos. A maioria dos estudos são retrospectivos, séries ou relatos de casos e até experiência pessoal. A taxa de conversão foi de 6,9%. A presença de análise estatística foi o dobro para os resumos publicados frente aos não publicados. Conclusão: os dados apresentados demonstram uma baixa produtividade científica da especialidade, já que as pesquisas realizadas não são publicadas, em sua maioria, como manuscritos completos. Os fatores preditores de publicação dos resumos foram: estudos multicêntricos, estudos contendo análise estatística, desenhos de estudo de maior nível de evidência e estudos premiados pelo congresso. Introdução disseminados eventos Métodos 201 2019 Resultados 175 retrospectivos pessoal 69 6 9 6,9% Conclusão especialidade publicadas multicêntricos 20 17 6,9 2 1 6,

ABSTRACT Objective: This study investigated the nutritional status, 25-hydroxyvitamin D (25OHD), albumin and risk factors associated with complications in patients with foot and ankle fragility fractures. Subjects and methods: Prospective study, developed with patients who suffered fractures due to fragility of the foot and ankle (n = 108); the type of fractured bone, fracture mechanisms and classification were studied and also pseudoarthrosis, treatment, surgical dehiscence, anthropometry, 25OHD and albumin. The Chi-square or Fisher's exact test, Mann-Whitney and Kruskal-Wallis tests were used in the statistical analysis and the multiple logistic regression analysis was used to identify the risk factors associated with complications. Results: The factors that, together, were associated with treatment complications were the level of 25OHD (p = 0.0055; OR = 0.868 [1,152]; 95% CI = 0.786; 0.959 [1.043;1.272]) and diabetes (p = 0.0034; OR = 30,181; 95% CI = 3.087; 295.036). The factors that, together, were associated with the presence of any complication, were age (p = 0.0139; OR = 1.058; 95% CI = 1.011; 1,106) and 25OHD level (p = 0.0198; OR = 0.917; 95% CI = 0.852; 0.986). There was a complication probability above 0.40 associated with lower 25OHD levels (values below 20 ng/mL) and older age (over 50 years). Conclusion: Lower or abnormal levels of 25OHD were associated with pseudoarthrosis, and age and 25OHD were both risk factors for treatment complications in patients with foot and ankle fractures. Objective status 25hydroxyvitamin hydroxyvitamin 25 25OHD, OHD , (25OHD) methods n 108 108) bone pseudoarthrosis dehiscence anthropometry Chisquare Chi square Fishers Fisher s test MannWhitney Mann Whitney KruskalWallis Kruskal Wallis Results that together p 0.0055 00055 0 0055 0868 868 0.86 1,152 1152 1 152 [1,152] 95 0.786 0786 786 0959 959 0.95 1.0431.272 10431272 1.043 1.272 043 272 [1.043;1.272] 0.0034 00034 0034 30,181 30181 30 181 3.087 3087 3 087 295.036. 295036 295.036 . 295 036 295.036) 0.0139 00139 0139 1.058 1058 058 1.011 1011 011 1,106 1106 106 0.0198 00198 0198 0.917 0917 917 0.852 0852 852 0.986. 0986 0.986 986 0.986) 040 40 0.4 values 2 ng/mL ngmL ng mL over 5 years. years years) Conclusion (25OHD 10 0.005 0005 005 086 86 0.8 1,15 115 15 [1,152 9 0.78 078 78 095 0.9 0431 1.0431.27 1043127 1043 1.04 1272 1.27 04 27 [1.043;1.272 0.003 0003 003 30,18 3018 18 3.08 308 08 29503 295.03 29 03 0.013 0013 013 1.05 105 05 1.01 101 01 1,10 110 0.019 0019 019 0.91 091 91 0.85 085 85 098 0.98 98 4 0. 0.00 000 00 8 1,1 11 [1,15 0.7 07 7 09 1.0431.2 104312 104 1.0 127 1.2 [1.043;1.27 30,1 301 3.0 2950 295.0 0.01 001 0.0 1, [1,1 1.0431. 10431 1. 12 [1.043;1.2 30, 3. 295. [1, 1.0431 [1.043;1. [1 [1.043;1 [ [1.043; [1.043 [1.04 [1.0 [1.

ABSTRACT BACKGROUND: Previous studies have shown a relationship between calf circumference (CC) and outcomes in hospitalized patients. AIMS: To investigate the relationship between CC and clinical and nutritional outcomes in older in-patients (OiP) in a surgery ward. METHODS: This was a cross-sectional study with 417 OiP in a surgery ward. Clinical variables, anthropometry, and nutritional screening instruments such as subjective global assessment (SGA), mini nutritional assessment (MNA), and nutritional risk screening (NRS) were used in the investigation. The tests Pearson’s chi-square, Mann-Whitney, Kruskal-Wallis, and Spearman’s coefficient, and multiple linear regression analyses were used to review the factors associated with CC. RESULTS: Lower CC values were found in the age group 80 years and over (p<0.0001), presence of complications (p=0.0269), NRS (p<0.0001), SGA (p<0.0001), and MNA (p<0.0001). Gender (p=0.0011; partial R2=0.01151), age (p=0.0002; partial R2=0.06032), body mass index (p≤0.0001; partial R2=0.40820), and arm circumference (p≤0.0001; partial R2=0.11890) are variables that together were associated with CC. There was also a relationship between SGA (p=0.0166; partial R2=0.00605) and absence of complications during hospitalization (p=0.0047; R2=0.01154) with CC. CONCLUSIONS: Gender, age, body mass index, and arm circumference were jointly associated with CC, in addition to SGA and absence of complications. The CC is a relevant indicator for OiP in the clinical practice. BACKGROUND (CC patients AIMS inpatients (OiP ward METHODS crosssectional cross sectional 41 anthropometry SGA, , (SGA) MNA, (MNA) (NRS investigation Pearsons Pearson s chisquare, chisquare chi square, square chi-square MannWhitney, MannWhitney Mann Whitney, Whitney Mann-Whitney KruskalWallis, KruskalWallis Kruskal Wallis, Wallis Kruskal-Wallis Spearmans Spearman coefficient RESULTS 8 p<0.0001, p00001 p p<0.0001 0 0001 (p<0.0001) p=0.0269, p00269 p=0.0269 0269 (p=0.0269) p<0.0001. . p=0.0011 p00011 0011 (p=0.0011 R2=0.01151, R2001151 R R2=0.01151 R2 01151 R2=0.01151) p=0.0002 p00002 0002 (p=0.0002 R2=0.06032, R2006032 R2=0.06032 06032 R2=0.06032) p≤0.0001 (p≤0.0001 R2=0.40820, R2040820 R2=0.40820 40820 R2=0.40820) R2=0.11890 R2011890 11890 p=0.0166 p00166 0166 (p=0.0166 R2=0.00605 R2000605 00605 p=0.0047 p00047 0047 (p=0.0047 R2=0.01154 R2001154 01154 CONCLUSIONS practice 4 (SGA (MNA p0000 p<0.000 000 (p<0.0001 p0026 p=0.026 026 (p=0.0269 p=0.001 p0001 001 (p=0.001 R200115 R2=0.0115 0115 p=0.000 (p=0.000 R200603 R2=0.0603 0603 p≤0.000 (p≤0.000 R204082 R2=0.4082 4082 R2=0.1189 R201189 1189 p=0.016 p0016 016 (p=0.016 R2=0.0060 R200060 0060 p=0.004 p0004 004 (p=0.004 p000 p<0.00 00 (p<0.000 p002 p=0.02 02 (p=0.026 p=0.00 (p=0.00 R20011 R2=0.011 011 R20060 R2=0.060 060 p≤0.00 (p≤0.00 R20408 R2=0.408 408 R2=0.118 R20118 118 p=0.01 p001 01 (p=0.01 R2=0.006 R20006 006 p00 p<0.0 (p<0.00 p=0.0 (p=0.02 (p=0.0 R2001 R2=0.01 R2006 R2=0.06 06 p≤0.0 (p≤0.0 R2040 R2=0.40 40 R2=0.11 R2011 11 R2=0.00 R2000 p0 p<0. (p<0.0 p=0. (p=0. R200 R2=0.0 p≤0. (p≤0. R204 R2=0.4 R2=0.1 R201 1 p<0 (p<0. p=0 (p=0 R20 R2=0. p≤0 (p≤0 p< (p<0 p= (p= R2=0 p≤ (p≤ (p< (p R2=

RESUMO RACIONAL: Estudos anteriores mostraram uma relação entre a circunferência da panturrilha (CP) e desfechos em pacientes hospitalizados. OBJETIVOS: Investigar a relação entre CP e desfecho clínico e nutricional em pacientes idosos hospitalizados (PIH) em uma enfermaria cirúrgica. MÉTODOS: Este foi um estudo transversal com 417 PIH em uma enfermaria de cirurgia. Variáveis clínicas, antropometria e instrumentos de triagem nutricional como avaliação subjetiva global (ASG), mini avaliação nutricional (MAN) e triagem de risco nutricional (NRS) foram utilizados na investigação. Qui-quadrado, Mann-Whitney, Kruskal-Wallis, coeficiente de Spearman e análise de regressão linear múltipla foram usados para analisar os fatores associados a CP. RESULTADOS: Menores valores de CP foram encontrados na faixa etária de 80 anos (p<0,0001), complicações (p=0,0269), risco nutricional pelo NRS (p<0,0001), ASG (p<0,0001) e MAN (p<0,0001). Sexo (p=0,0011; R2 parcial=0,01151), idade (p=0,0002; R2 parcial=0,06032), IMC (p≤0,0001; R2 parcial=0,40820) e circunferência do braço (CB) (p≤0,0001; R2 parcial=0,11890) foram variáveis que juntas estiveram associadas com a CP. Também houve relação entre ASG (p=0,0166; R2 parcial=0,00605) e ausência de complicações durante a internação (p=0,0047; R2= 0,01154) com a CP. CONCLUSÕES: Sexo, idade, IMC e CB associaram-se conjuntamente com CP, ASG e ausência de complicações. CP é um indicador relevante em PIH na prática clínica. RACIONAL (CP OBJETIVOS (PIH cirúrgica MÉTODOS 41 cirurgia clínicas ASG, , (ASG) (MAN (NRS investigação Quiquadrado, Quiquadrado Qui quadrado, quadrado Qui-quadrado MannWhitney, MannWhitney Mann Whitney, Whitney Mann-Whitney KruskalWallis, KruskalWallis Kruskal Wallis, Wallis Kruskal-Wallis RESULTADOS 8 p<0,0001, p00001 p p<0,0001 0 0001 p=0,0269, p00269 p=0,0269 0269 (p=0,0269) (p<0,0001 p<0,0001. . p=0,0011 p00011 0011 (p=0,0011 R parcial=0,01151, parcial001151 parcial parcial=0,01151 01151 parcial=0,01151) p=0,0002 p00002 0002 (p=0,0002 parcial=0,06032, parcial006032 parcial=0,06032 06032 parcial=0,06032) p≤0,0001 (p≤0,0001 parcial=0,40820 parcial040820 40820 (CB parcial=0,11890 parcial011890 11890 p=0,0166 p00166 0166 (p=0,0166 parcial=0,00605 parcial000605 00605 p=0,0047 p00047 0047 (p=0,0047 0,01154 001154 01154 CONCLUSÕES associaramse associaram se clínica 4 (ASG p0000 p<0,000 000 p0026 p=0,026 026 (p=0,0269 (p<0,000 p=0,001 p0001 001 (p=0,001 parcial00115 parcial=0,0115 0115 p=0,000 (p=0,000 parcial00603 parcial=0,0603 0603 p≤0,000 (p≤0,000 parcial=0,4082 parcial04082 4082 parcial=0,1189 parcial01189 1189 p=0,016 p0016 016 (p=0,016 parcial=0,0060 parcial00060 0060 p=0,004 p0004 004 (p=0,004 0,0115 00115 p000 p<0,00 00 p002 p=0,02 02 (p=0,026 (p<0,00 p=0,00 (p=0,00 parcial0011 parcial=0,011 011 parcial0060 parcial=0,060 060 p≤0,00 (p≤0,00 parcial=0,408 parcial0408 408 parcial=0,118 parcial0118 118 p=0,01 p001 01 (p=0,01 parcial=0,006 parcial0006 006 0,011 p00 p<0,0 p=0,0 (p=0,02 (p<0,0 (p=0,0 parcial001 parcial=0,01 parcial006 parcial=0,06 06 p≤0,0 (p≤0,0 parcial=0,40 parcial040 40 parcial=0,11 parcial011 11 parcial=0,00 parcial000 0,01 p0 p<0, p=0, (p<0, (p=0, parcial00 parcial=0,0 p≤0, (p≤0, parcial=0,4 parcial04 parcial=0,1 parcial01 1 0,0 p<0 p=0 (p<0 (p=0 parcial0 parcial=0, p≤0 (p≤0 0, p< p= (p< (p= parcial=0 p≤ (p≤ (p parcial=

RESUMO Contexto A prevalência de pacientes idosos hospitalizados tem crescido substancialmente e impactado os serviços de saúde hospitalar. Desta forma, acredita-se que uma investigação do estado nutricional, associado a situações clínicas variadas em pacientes idosos, poderia contribuir para ações de intervenção hospitalar multidisciplinares e de cuidado nutricional adequadas para esta população. Objetivo Investigar a relação entre dois instrumentos de triagem nutricional em pacientes idosos hospitalizados e comparar variáveis clínicas entre estes dois instrumentos. Métodos Estudo retrospectivo com pacientes idosos hospitalizados (n=277), sendo investigado a concordância entre dois instrumentos de triagem nutricional. Os dados foram analisados pelos testes McNemar, qui-quadrado, Fisher, Mann-Whitney e o coeficiente kappa para a avaliação de concordância. Resultados Houve diferença significativa (P=0,0002) entre as classificações de risco nutricional pelos dois instrumentos de triagem nutricional e concordância moderada (k=0,5430) entre eles. Verificou-se associação entre triagem de risco nutricional e idade (P=0,0255), tempo de internação (P<,0001), sexo (P=0,0365) e doenças (P=0,0001). Houve associação entre a Mini Avaliação Nutricional e tempo de internação (P<0,0001), doenças (P=0,0001) e evolução do peso corporal (P=0,0479). Conclusão Triagem de risco nutricional e a Mini Avaliação Nutricional apresentam concordância moderada para a avaliação de pacientes idosos.

ABSTRACT Background The prevalence of hospitalized elderly patients has grown substantially and has impacted the hospital health services. Thus, it is believed that an investigation of the nutritional status associated with different clinical situations in elderly patients could contribute to multidisciplinary hospital intervention and nutritional care actions suitable for this population. Objective To investigate the relationship between two nutritional screening instruments in hospitalized older patients and to compare clinical variables between these two instruments. Methods Retrospective study with hospitalized older patients (n=277), investigating the agreement between two nutritional screening instruments. The data were analyzed using the McNemar, chi-square, Fisher, Mann-Whitney tests and the kappa coefficient for the agreement assessment. Results There was a significant difference (P=0.0002) between the nutritional risk classifications of the two nutritional screening instruments and moderate agreement (k=0.5430) between them. The association between nutritional risk screening and age (P=0.0255), length of hospital stay (P<0.0001), gender (P=0.0365) and illness (P=0.0001) were assessed. There was an association between Mini Nutritional Assessment and length of stay (P<0.0001), illness (P=0.0001) and body weight evolution (P=0.0479). Conclusion The nutritional risk screening and Mini Nutritional Assessment showed moderate agreement in the assessment of elderly patients.

RESUMO Introdução: recentemente tem-se estudado a variável densidade linfonodal como possível influenciador na sobrevida de pacientes com diagnóstico de câncer de cabeça e pescoço. Objetivo: analisar a relação entre a densidade linfonodal e a sobrevida de pacientes recidivados previamente submetidos a cirurgia de esvaziamento cervical por carcinoma espinocelular de cabeça e pescoço. Método: foram analisados retrospectivamente 71 prontuários pacientes atendidos no Serviço de Cirurgia de Cabeça e Pescoço da Pontifícia Universidade Católica de Campinas que tinham sido submetidos a cirurgia de esvaziamento cervical e apresentaram recidiva tumoral entre os anos de 2006 e 2019. Dados relativos ao paciente e ao tumor tais como: idade, sexo, cor da pele, tabagismo, etilismo, localização do tumor primário, características anatomopatológicas e status linfonodal foram correlacionados ao tempo de sobrevida dos indivíduos. Resultados: encontramos predominância do sexo masculino e a média de idade foi de 59,5 anos. O sítio primário mais frequente foi a cavidade oral seguido da laringe e orofaringe. A taxa de mortalidade foi de 53,52% e a densidade linfonodal média 0,28. Encontramos influência na sobrevida com significância estatística para os parâmetros: densidade linfonodal, número de linfonodos dissecados e acometidos, estadiamento T e N, tipo de tratamento proposto (paliativo ou cirúrgico), presença de margens comprometidas no tumor primário e extravasamento linfonodal. Conclusão: o cálculo da densidade linfonodal em pacientes recidivados após cirurgia de esvaziamento cervical por carcinoma espinocelular de cabeça e pescoço deve ser levado em consideração durante o planejamento terapêutico e na avaliação prognóstica devido à sua direta influencia na sobrevida dos indivíduos.

ABSTRACT Introduction: the variable lymph node ratio has recently been studied as a possible influencer in the survival of patients diagnosed with head and neck cancer. Objective: to analyze the correlation between lymph node density and survival of recurred disease patients previously submitted to cervical dissection surgery due to head and neck squamous cell carcinoma. Method: we retrospectively analyzed 71 medical records of patients treated at the Head and Neck Surgery Service of the Pontifícia Universidade Católica de Campinas who had undergone cervical dissection surgery and presented tumor recurrence between 2006 and 2019. Patient and tumor data such as age, gender, skin color, smoking, alcohol consumption, location of the primary tumor, anatomopathological characteristics and lymph node status were correlated with the survival time. Results: we found a predominance of males and the mean age was 59.5 years. The most frequent primary site was the oral cavity followed by the larynx and oropharynx. The mortality rate was 53.52% and the mean lymph node ratio 0.28. We found influence on survival with statistical significance for the parameters: lymph node ratio, number of dissected and affected lymph nodes, T and N staging, type of treatment proposed (palliative or surgical), presence of compromited margins in the primary tumor and lymph node extravasation. Conclusion: the calculation of lymph node density in patients with recurred disease after cervical dissection surgery by head and neck squamous cell carcinoma should be taken into account during therapeutic planning and prognostic evaluation due to its direct influence on the survival.

Abstract Objective: the aim of this study was to assess weight loss, diet prescribed, and nutritional status in hospitalized patients, as well as their associated factors. Methods: weight loss during hospitalization, nutritional status, disease type, and prescribed diet were investigated in a retrospective study in 621 hospitalized patients. The chi-squared, Fisher's, Mann-Whitney, and Kruskal-Wallis tests were used for statistical analysis. To identify factors associated with weight loss a logistic regression analysis was performed. The significance level adopted for statistical tests was 5 %. Results: patients who experienced weight loss during hospitalization were associated with longer hospital stays (p < 0.0001; OR = 1.052; 95 % CI = 1.030 to 1.073), malnourishment according to the subjective global assessment (p = 0.0358; OR = 1.520; 95 % CI = 1,028 to 2,248), digestive disorders (p = 0.0081; OR = 3.177; 95 % CI = 1.351 to 7.469), and digestive neoplasms (p = 0.0407; OR = 2.410; 95 % CI = 1.038 to 5.597). Conclusion: weight loss during hospitalization was associated with neoplasms, digestive diseases, malnutrition, and length of stay.

Resumen Objetivo: el objetivo de este estudio fue evaluar la pérdida de peso, la dieta prescrita y el estado nutricional de pacientes hospitalizados y sus factores asociados. Métodos: se investigó la pérdida de peso durante la hospitalización, el estado nutricional, el tipo de enfermedad y la dieta prescrita en un estudio retrospectivo de 621 pacientes hospitalizados. Las pruebas del chi cuadrado, Fisher, Mann-Whitney y Kruskal-Wallis se utilizaron para el análisis estadístico. Para identificar los factores asociados con la pérdida de peso se utilizó la regresión logística. El nivel de significación adoptado para las pruebas estadísticas fue del 5 %. Resultados: los casos de pérdida de peso durante la hospitalización se asociaron a las estancias hospitalarias más largas (p < 0,0001; OR = 1,052; IC 95 % = 1,030; 1,073), la desnutrición según la evaluación global subjetiva (p = 0,0358; OR = 1,520; IC 95 % = 1,028; 2,248) los trastornos digestivos (p = 0,0081; OR = 3,177; IC 95 % = 1,351; 7,469) y las neoplasias digestivas (p = 0,0407; OR = 2,410; IC 95 % = 1,038; 5,597). Conclusión: la pérdida de peso durante la hospitalización se asoció con las neoplasias y las enfermedades digestivas, la desnutrición y la duración de la estancia.

Abstract Objectives To evaluate the serrated lesion detection rate in colonoscopy at a specialized clinic and its role as quality criteria for endoscopic examination. Methods This is an observational cross-sectional study with all patients that underwent colonoscopy between October 2018 and May 2019, performed by an experimented physician. A questionnaire was answered before the examination by the patient, and another questionnaire after the colonoscopy was answered by themedical team. All polyps identified were removed and sent to the same pathologist for analysis. Results A total of 1,000 colonoscopies were evaluated. The average age of the patients was 58.9 years old, and most of them were female (60.6%). In 62.5% of the procedures, polyps were removed, obtaining a total of 1,730 polyps, of which 529 were serrated lesions, being 272 sessile serrated lesions (SSL). This data resulted in a serrated lesion detection rate (SDR) of 29.2%, and of 14% when considering only the SSL detection rate (SSLDR). The right colon had higher rates, with 22.3% SDR and 15.3% SSLDR. Screening colonoscopies also presented a higher serrated detection rate, of 20%, followed by diagnostics and follow-up exams. Smoking was the only risk factor associated with higher serrated detection rate. Conclusions The serrated lesion detection rate is higher than the ones already previously suggested and the have the higher rates were stablished in the right colon and on screening exams.

Resumo Objetivos: avaliar o impacto da codetecção de Influenza A (FluA) e Vírus Sincicial Respiratório (VSR) por meio de testes imunocromatográficos rápidos em tempo real, em pacientes menores de 2 anos em hospital público e universitário. Métodos: estudo de coorte retrospectivo foi conduzido para analisar os desfechos clínicos de crianças hospitalizadas com doença respiratória viral com resultados positivos do teste rápido imunocromatográfico para VSR e/ou FluA, de 2013 a 2018. Um modelo de regressão logística foi ajustado para analisar preditores de intubação orotraqueal durante a internação. Resultados: foram analisados 220 casos: RSV (192), FluA (9) eco-detecção (19). A letalidade foi de 1,8% (2 casos) e 88% (194) casos em menores de 1 ano. O tempo médio de internação foi maior nos pacientes com codetecção. As variáveis significativamente associadas à intubação orotraqueal foram: menor idade em meses, comorbidades, codetecção de VSR e Flu-A e pneumonia bacteriana durante a internação. Conclusões: codetecção VSR e FluA foi associada a prognósticos clínicos desfavoráveis. O teste rápido fornece informações importantes a beira-leito, pois os painéis moleculares não são amplamente acessíveis em hospitais públicos. O diagnóstico rápido permite a avaliação e tratamento oportunos.

Abstract Objectives: the aim of this study is to evaluate the impact of co-detection of Flu A and RSV using rapid immunochromatographic tests at the point of care, in pediatric patients under 2 years of age in a general hospital. Methods: a retrospective cohort study was conducted to analyze clinical outcomes in hospitalized infants with viral respiratory disease with positive results of rapid immunochromatographic test for RSV and/or Flu-A, from 2013 to 2018. A logistic regression model was adjusted to analyze predictors of orotracheal intubation during hospitalization. Results: we analyzed 220 cases: RSV (192), Flu-A (9), co-detection (19). Lethality rate was 1.8% (2 cases), and 88% (194) were under 1 year of age. Mean time of hospitalizations was higher in patients with co-detection. Variables significantly associated with orotracheal intubation were: younger age in months, comorbidities, RSV and Flu-A co-detection, and bacterial pneumonia during hospitalization. Conclusions: RSV and Flu-Aco-detection was associated with the least favorable clinical prognoses in this study. Rapid test diagnosis may provide important information at the point of care, because molecular panels are not widely accessible in general hospitals. Rapid diagnosis allows timely evaluation and treatment.

RESUMO CONTEXTO: Pacientes oncológicos podem apresentar alterações gastrointestinais que influenciam o estado nutricional. OBJETIVO: Investigar a ocorrência de alterações gastrointestinais decorrentes do tratamento ambulatorial de quimioterapia, em pacientes oncológicos. MÉTODOS: Num estudo longitudinal retrospectivo, investigou-se o estado nutricional e as alterações gastrointestinais (náuseas, vômito, diarreia, constipação, mucosite, disfagia, xerostomia, inapetência, disgeusia e pirose) de pacientes oncológicos (n=187), em acompanhamento ambulatorial de quimioterapia. Para o estudo dos parâmetros ao longo do tempo, utilizou-se o método das equações de estimação generalizadas (EEG). Também foram utilizados os testes de Kruskal-Wallis, Mann-Whitney e o coeficiente de Spearman, com nível de significância de 5%. RESULTADOS: A maioria dos pacientes era do sexo feminino (63,64%) e a média de idade foi 57,5±12,1 anos. Os sintomas mais frequentes foram náuseas (18,54%); inapetência (18,31%); constipação intestinal (11,58%); diarreia (7,98%); xerostomia (7,59%) e vômito (7,43%). O estado nutricional não apresentou alterações relevantes (P=0,7594). No entanto, observou-se maior prevalência de eutrofia, seguido do sobrepeso e o vômito apresentou diferença significativa (P=0,0211). O sintoma de náusea apresentou diferença significativa com maior prevalência na neoplasia colorretal, quando comparado à neoplasia de mama (P=0,0062); assim como o vômito nas neoplasias de pulmão e colorretal (P=0,0022). E a disfagia, na neoplasia de cabeça e pescoço, quando comparada às demais neoplasias (P<0,001). Houve diferença estatisticamente significante entre o número de consultas médicas e sexo (P=0,0102) e entre disfagia e sexo (P<0,0001). CONCLUSÃO: Os achados encontrados no estudo permitem reforçar a necessidade do acompanhamento de sinais e sintomas, bem como do estado nutricional, de pacientes em acompanhamento ambulatorial de quimioterapia.

ABSTRACT BACKGROUND: Cancer patients may have gastrointestinal changes that influence nutritional status. OBJECTIVE: To investigate the occurrence of gastrointestinal changes resulting from outpatient chemotherapy treatment in cancer patients. METHODS: In a retrospective longitudinal study, the nutritional status and chemotherapy gastrointestinal changes (nausea, vomit, diarrhea, constipation, mucositis, dysphagia, xerostomia, inappetence, dysgeusia and heartburn) in cancer patients (n=187) were investigated in an outpatient follow-up. For the study of the parameters over time, the generalized estimating equation (GEE) method was used. Kruskal-Wallis, Mann-Whitney tests and Spearman coefficient, at a significance level of 5% were also used. RESULTS: The majority of the patients were female (63.64%) and the mean age was 57.5±12.1 years. The most frequent symptoms were nausea (18.54%); inappetence (18.31%); intestinal constipation (11.58%); diarrhea (7.98%); xerostomia (7.59%) and vomiting (7.43%). The nutritional status did not exhibit any relevant changes (P=0.7594). However, a higher prevalence of eutrophy was observed, followed by overweight; vomiting exhibited a significant difference (P=0.0211). The nausea symptom exhibited a significant difference with a higher prevalence of colorectal neoplasia when compared to breast neoplasia (P=0.0062); as well as vomiting in lung and colorectal neoplasias (P=0.0022), and dysphagia, in head and neck neoplasia, when compared to other neoplasms (P<0.001). There was a statistically significant difference between the number of medical appointments and gender (P=0.0102) and between dysphagia and gender (P<0.0001). CONCLUSION: The study findings enhance the need for signs and symptoms follow up, as well as nutritional status follow up of patients undergoing outpatient chemotherapy.