Pesquisa | SciELO

Abstract Objective To review current literature to support the use of mesna as a preventive therapy for hemorrhagic cystitis and bladder cancer in patients with systemic autoimmune diseases and systemic vasculitis treated with cyclophosphamide. Materials and methods The search for articles was conducted systematically through MEDLINE, LILACS, Cochrane Library, and Embase databases. Only articles in English were selected. For available records, titles and abstracts were selected independently by two investigators. Results Eighteen studies were selected for analysis. The known adverse effects of cyclophosphamide were hematological toxicity, infections, gonadal toxicity, teratogenicity, increased risk for malignancy and hemorrhagic cystitis. Long-term toxicity was highly dependent on cyclophosphamide cumulative dose. The risk of bladder cancer is especially higher in long-term exposure and with cumulative doses above 36 g. The risk remains high for years after drug discontinuation. Hemorrhagic cystitis is highly correlated with cumulative dose and its incidence ranges between 12 and 41%, but it seems to be lower with new regimens with reduced cyclophosphamide dose. No randomized controlled trials were found to analyze the use of mesna in systemic autoimmune rheumatic diseases and systemic vasculitis. Retrospective studies yielded conflicting results. Uncontrolled prospective studies with positive results were considered at high risk of bias. No evidence was found to support the use of mesna during the treatment with cyclophosphamide for autoimmune diseases or systemic vasculitis to prevent hemorrhagic cystitis and bladder cancer. In the scenarios of high cumulative cyclophosphamide dose (i.e., > 30 g), patients with restricted fluid intake, neurogenic bladder, therapy with oral anticoagulants, and chronic kidney disease, mesna could be considered. Conclusion The current evidence was found to be insufficient to support the routine use of mesna for the prophylaxis of hemorrhagic cystitis and bladder cancer in patients being treated for systemic autoimmune diseases and systemic vasculitis with cyclophosphamide. The use may be considered for selected cases. MEDLINE LILACS Library databases records investigators analysis infections teratogenicity Longterm Long term longterm long 3 g discontinuation 1 41 41% bias i.e., ie i e (i.e. g, , g) intake anticoagulants disease cases 4 i.e. (i.e i.e

https://doi.org/10.1186/s42358-024-00380-0

Nurse leadership practices during the Covid-19 pandemic in university hospitals Covid19 Covid 19 Covid-1 Covid1 1 Covid-
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Silveira, Vitória Carolina

; Cechinel-Peiter, Caroline

; Santos, José Luís Guedes dos

; Varanda, Patrícia Alves Galhardo

; Silva, Gilberto Tadeu Reis da

; Lanzoni, Gabriela Marcellino de Melo

Revista Gaúcha de Enfermagem

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2024, Volume 45 elocation e20230289

Resumo: En Pt Es | Texto: En Pt Es | PDF: En | PDF: Pt | PDF: Es

ABSTRACT Objective: to analyze the leadership practices among nurses in face of COVID-19 pandemic in university hospitals in Brazil. Method: this is a multicenter, qualitative and exploratory-descriptive research. Semi-structured interviews were conducted with 139 nurses who worked in the care for patients with COVID-19 in Brazilian university hospitals. Thematic content analysis was carried out with support of Iramuteq® software. Results: Three categories were obtained: 1) Leadership practices with individual emphasis, highlighting decision-making agility and technical-scientific knowledge as relevant elements for professional performance; 2) Leadership practices with emphasis on the team and direct care for critical patients, presents the challenges faced in managing human resources amidst a high number of infections and professional absences; and 3) Leadership practices with emphasis on Safety and material management, presenting strategies to enhance patient and professional safety despite difficulties related to the supply of materials. Conclusion: leadership practices such as adaptive capacity, transmission of trust in the leader, collaborative decision-making, encouraging team development, management of human and material resources, and effective communication allowed nurses to cope with the critical moments of the pandemic. Objective COVID19 COVID 19 COVID-1 Brazil Method multicenter exploratorydescriptive exploratory descriptive research Semistructured Semi structured 13 Iramuteq software Results obtained 1 decisionmaking decision making technicalscientific technical scientific performance 2 absences 3 materials Conclusion capacity leader decisionmaking, making, development COVID1 COVID-

RESUMO Objetivo: analisar as práticas de liderança entre enfermeiros durante o enfrentamento da Covid-19 em hospitais universitários no Brasil. Método: pesquisa multicêntrica, qualitativa e exploratório-descritiva. Foram realizadas entrevistas semiestruturadas com 139 enfermeiros que atuaram no cuidado a pacientes com Covid-19 em hospitais universitários brasileiros. Análise de conteúdo temática realizada com auxílio do software Iramuteq®. Resultados: obteve-se três categorias: 1) Práticas de liderança com ênfase individual, traz a agilidade na tomada de decisões, e o conhecimento técnico-científico como elementos relevantes para um bom desempenho profissional; 2) Práticas de liderança com ênfase na equipe e cuidado direto ao paciente crítico, apresenta os desafios enfrentados em gerir os recursos humanos diante do alto número de infecções e afastamentos profissionais; e 3) Práticas de liderança com ênfase na Segurança e gestão de materiais, apresenta as estratégias para aprimorar a segurança dos pacientes e profissionais, apesar das dificuldades relacionadas à oferta de insumos. Conclusão: práticas de liderança como capacidade adaptativa, transmissão de confiança na figura do líder, tomada de decisão colaborativa, incentivo ao desenvolvimento da equipe, gestão de recursos humanos, materiais e comunicação efetiva permitiram aos enfermeiros enfrentar os momentos críticos da pandemia. Objetivo Covid19 Covid 19 Covid-1 Brasil Método multicêntrica exploratóriodescritiva. exploratóriodescritiva exploratório descritiva. descritiva exploratório-descritiva 13 brasileiros Iramuteq Iramuteq® Resultados obtevese obteve se categorias 1 individual decisões técnicocientífico técnico científico profissional 2 crítico profissionais 3 insumos Conclusão adaptativa líder colaborativa pandemia Covid1 Covid-

RESUMEN Objetivo: este estudio tiene como objetivo analizar las prácticas de liderazgo entre enfermeros frente a la pandemia de Covid-19 en hospitales universitarios de Brasil. Método: investigación multi sitio, cualitativa, de tipo exploratorio-descriptivo, a partir de entrevistas individuales semiestructuradas aplicadas a 139 enfermeros que actuaban en el cuidado de pacientes con Covid-19 em diez hospitales universitarios brasileños. Análisis de contenido temático realizado con ayuda del software Iramuteq®. Resultados: se encontraron tres categorías: 1) Prácticas de liderazgo con énfasis individual, que presentan la disposición en el proceso de toma de decisiones y el conocimiento científico como elementos importantes para sustentar un alto desempeño profesional; 2) Prácticas de liderazgo con énfasis en el equipo y atención directa al paciente crítico, lo que presenta desafíos para la gestión de recursos humanos, considerando la alta incidencia de infección entre los profesionales; y 3) Prácticas de liderazgo con énfasis en seguridad y gestión de materiales, con estrategias para mejorar la seguridad del paciente y del profesional, a pesar de las dificultades relacionadas con la escasez de material. Conclusión: prácticas de liderazgo como capacidad de adaptación, transmisión de confianza en el líder, toma de decisiones colaborativa, estímulo al desarrollo del equipo, gestión de recursos humanos y materiales y comunicación efectiva, permitieron a los enfermeros enfrentaren los momentos más críticos de la pandemia. Objetivo Covid19 Covid 19 Covid-1 Brasil Método sitio cualitativa exploratoriodescriptivo, exploratoriodescriptivo exploratorio descriptivo, descriptivo exploratorio-descriptivo 13 brasileños Iramuteq Iramuteq® Resultados categorías 1 individual profesional 2 crítico profesionales 3 material Conclusión adaptación líder colaborativa efectiva Covid1 Covid-

https://doi.org/10.1590/1983-1447.2024.20230289.en

A PESQUISA APLICADA PAUTANDO O PROCESSO DECISÓRIO EM POLÍTICAS PÚBLICAS: A EXPERIÊNCIA DA ESCOLA NACIONAL DE ADMINISTRAÇÃO PÚBLICA PÚBLICAS
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Palotti, Pedro Lucas de Moura

; Marra, Carolina Alves

; Camões, Marizaura Reis de Souza

; Souza, Pedro Masson Sesconetto

Cadernos Gestão Pública e Cidadania

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2023, Volume 28 elocation e88074

Resumo: Es En Pt | Texto: Es En Pt | PDF: Es | PDF: En | PDF: Pt

RESUMEN El presente artículo tiene como objetivo comprender el proceso de aplicación de estrategias de formulación de políticas basadas en evidencias en la enseñanza de la administración pública en Brasil. El estudio se centra en el papel que juegan las escuelas de gobierno como instituciones de enseñanza e investigación aplicadas. A través del estudio de caso de la trayectoria reciente de la Escola Nacional de Administração Pública, se observa que la producción de evidencias para las políticas públicas y el puente entre enseñanza y servicio público son elementos centrales del desempeño de las escuelas de gobierno, que contribuyen a que los programas de aprendizaje se mantengan relevantes y actualizados con las tendencias sociales y económicas, así como con las políticas emergentes y las prioridades gubernamentales. Brasil aplicadas Pública económicas gubernamentales

ABSTRACT This article aims to understand the application of evidence-based policymaking strategies in teaching public administration in Brazil. The study focuses on the role of schools of government as applied teaching and research institutions, presenting the case study of the recent trajectory of ENAP (the National School of Public Administration). The findings show that the production of evidence for public policies and the bridge between teaching and public service are central elements of the performance of schoos of government, contributing so that learning programs remain relevant and up-to-date with social and economic trends, as well as emerging policies and government priorities. evidencebased based Brazil institutions Administration. Administration . Administration) uptodate up date trends priorities

RESUMO O presente artigo tem como objetivo compreender o processo de aplicação de estratégias de evidence-based policymaking no ensino da administração pública no Brasil. O estudo centra-se no papel exercido pelas escolas de governo como instituições de ensino e pesquisa aplicados. Por meio do estudo de caso da trajetória recente da Escola Nacional de Administração Pública, observa-se que a produção de evidências para as políticas públicas e a ponte entre ensino e serviço púlico são elementos centrais da atuação de escolas de governo, contribuindo para que os programas de aprendizagem permaneçam relevantes e atualizados com as tendências sociais e econômicas, bem como políticas emergentes e prioridades do governo. evidencebased evidence based Brasil centrase centra se aplicados Pública observase observa econômicas

https://doi.org/10.12660/cgpc.v28.88074

Human sporotrichosis: recommendations from the Brazilian Society of Dermatology for the clinical, diagnostic and therapeutic management
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Orofino-Costa, Rosane

; Freitas, Dayvison Francis Saraiva

; Bernardes-Engemann, Andréa Reis

; Rodrigues, Anderson Messias

; Talhari, Carolina

; Ferraz, Claudia Elise

; Veasey, John Verrinder

; Quintella, Leonardo

; Sousa, Maria Silvia Laborne Alves de

; Vettorato, Rodrigo

; Almeida-Paes, Rodrigo de

; Macedo, Priscila Marques de

Anais Brasileiros de Dermatologia

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Nov 2022, Volume 97 Nº 6 Páginas 757 - 777

Resumo: En | Texto: En | PDF: En

Abstract Background: The increase in the zoonotic epidemic of sporotrichosis caused by Sporothrix brasiliensis, which started in the late 1990s in Rio de Janeiro and is now found in almost all Brazilian states, has been equally advancing in neighboring countries of Brazil. Changes in the clinical-epidemiological profile, advances in the laboratory diagnosis of the disease, and therapeutic difficulties have been observed throughout these almost 25 years of the epidemic, although there is no national consensus. The last international guideline dates from 2007. Objectives: Update the clinical classification, diagnostic methods and recommendations on the therapeutic management of patients with sporotrichosis. Methods: Twelve experts in human sporotrichosis were selected from different Brazilian regions, and divided into three work groups: clinical, diagnosis and treatment. The bibliographic research was carried out on the EBSCOHost platform. Meetings took place via electronic mail and remote/face-to-face and hybrid settings, resulting in a questionnaire which pointed out 13 divergences, resolved based on the opinion of the majority of the participants. Results: The clinical classification and laboratory diagnosis were updated. Therapeutic recommendations were made for the different clinical forms. Conclusions: Publication of the first national recommendation, carried out by the Brazilian Society of Dermatology, aimed at the Brazilian scientific community, especially dermatologists, infectologists, pediatricians, family medicine personnel, and laboratory professionals who work in the management of human sporotrichosis.

https://doi.org/10.1016/j.abd.2022.07.001

Guidelines on COVID-19 vaccination in patients with immune-mediated rheumatic diseases: a Brazilian Society of Rheumatology task force
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Tavares, Anna Carolina Faria Moreira Gomes

; Melo, Ana Karla Guedes de

; Cruz, Vítor Alves

; Souza, Viviane Angelina de

; Carvalho, Joana Starling de

; Machado, Ketty Lysie Libardi Lira

; Valadares, Lilian David de Azevedo

; Reis Neto, Edgard Torres dos

; Rezende, Rodrigo Poubel Vieira de

; Guimarães, Maria Fernanda Brandão de Resende

; Ferreira, Gilda Aparecida

; Braz, Alessandra de Sousa

; Vieira, Rejane Maria Rodrigues de Abreu

; Pinheiro, Marcelo de Medeiros

; Ribeiro, Sandra Lúcia Euzébio

; Bica, Blanca Elena Gomes Rios

; Baptista, Kátia Lino

; Costa, Izaias Pereira da

; Marques, Claudia Diniz Lopes

; Lopes, Maria Lúcia Lemos

; Martinez, José Eduardo

; Giorgi, Rina Dalva Neubarth

; Mota, Lícia Maria Henrique da

; Loures, Marcos Antônio Araújo da Rocha

; Paiva, Eduardo dos Santos

; Monticielo, Odirlei André

; Xavier, Ricardo Machado

; Kakehasi, Adriana Maria

; Pileggi, Gecilmara Cristina Salviato

Advances in Rheumatology

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2022, Volume 62 elocation 3

Resumo: En | Texto: En | PDF: En

Abstract Objective: To provide guidelines on the coronavirus disease 2019 (COVID-19) vaccination in patients with immune-mediated rheumatic diseases (IMRD) to rheumatologists considering specific scenarios of the daily practice based on the shared-making decision (SMD) process. Methods: A task force was constituted by 24 rheumatologists (panel members), with clinical and research expertise in immunizations and infectious diseases in immunocompromised patients, endorsed by the Brazilian Society of Rheumatology (BSR), to develop guidelines for COVID-19 vaccination in patients with IMRD. A consensus was built through the Delphi method and involved four rounds of anonymous voting, where five options were used to determine the level of agreement (LOA), based on the Likert Scale: (1) strongly disagree; (2) disagree, (3) neither agree nor disagree (neutral); (4) agree; and (5) strongly agree. Nineteen questions were addressed and discussed via teleconference to formulate the answers. In order to identify the relevant data on COVID-19 vaccines, a search with standardized descriptors and synonyms was performed on September 10th, 2021, of the MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, ClinicalTrials.gov, and LILACS to identify studies of interest. We used the Newcastle–Ottawa Scale to assess the quality of nonrandomized studies. Results: All the nineteen questions-answers (Q&A) were approved by the BSR Task Force with more than 80% of panelists voting options 4—agree—and 5—strongly agree—, and a consensus was reached. These Guidelines were focused in SMD on the most appropriate timing for IMRD patients to get vaccinated to reach the adequate covid-19 vaccination response. Conclusion: These guidelines were developed by a BSR Task Force with a high LOA among panelists, based on the literature review of published studies and expert opinion for COVID-19 vaccination in IMRD patients. Noteworthy, in the pandemic period, up to the time of the review and the consensus process for this document, high-quality evidence was scarce. Thus, it is not a substitute for clinical judgment.

https://doi.org/10.1186/s42358-022-00234-7

COVID-19: The question of genetic diversity and therapeutic intervention approaches
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Figueiredo, David Livingstone Alves

; Ximenez, João Paulo Bianchi

; Seiva, Fábio Rodrigues Ferreira

; Panis, Carolina

; Bezerra, Rafael dos Santos

; Ferrasa, Adriano

; Cecchini, Alessandra Lourenço

; Medeiros, Alexandra Ivo de

; Almeida, Ana Marisa Fusco

; Ramão, Anelisa

; Boldt, Angelica Beate Winter

; Moya, Carla Fredrichsen

; Chin, Chung Man

; Paula, Daniel de

; Rech, Daniel

; Gradia, Daniela Fiori

; Malheiros, Danielle

; Venturini, Danielle

; Tavares, Eliandro Reis

; Carraro, Emerson

; Ribeiro, Enilze Maria de Souza Fonseca

; Pereira, Evani Marques

; Tuon, Felipe Francisco

; Follador, Franciele Aní Caovilla

; Fernandes, Glaura Scantamburlo Alves

; Volpato, Hélito

; Cólus, Ilce Mara de Syllos

; Oliveira, Jaqueline Carvalho de

; Rodrigues, Jean Henrique da Silva

; Santos, Jean Leandro dos

; Visentainer, Jeane Eliete Laguila

; Brandi, Juliana Cristina

; Serpeloni, Juliana Mara

; Bonini, Juliana Sartori

; Oliveira, Karen Brajão de

; Fiorentin, Karine

; Lucio, Léia Carolina

; Faccin-Galhardi, Ligia Carla

; Ferreto, Lirane Elize Defante

; Lioni, Lucy Megumi Yamauchi

; Consolaro, Marcia Edilaine Lopes

; Vicari, Marcelo Ricardo

; Arbex, Marcos Abdo

; Pileggi, Marcos

; Watanabe, Maria Angelica Ehara

; Costa, Maria Antônia Ramos

; Giannini, Maria José S. Mendes

; Amarante, Marla Karine

; Khalil, Najeh Maissar

; Lima Neto, Quirino Alves de

; Herai, Roberto H.

; Guembarovski, Roberta Losi

; Shinsato, Rogério N.

; Mainardes, Rubiana Mara

; Giuliatti, Silvana

; Yamada-Ogatta, Sueli Fumie

; Gerber, Viviane Knuppel de Quadros

; Pavanelli, Wander Rogério

; Silva, Weber Claudio da

; Petzl-Erler, Maria Luiza

; Valente, Valeria

; Soares, Christiane Pienna

; Cavalli, Luciane Regina

; Silva Jr, Wilson Araujo

Genetics and Molecular Biology

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2021, Volume 44 Nº 1 elocation e20200452

Resumo: En | Texto: En | PDF: En

Abstract Coronavirus disease 2019 (COVID-19), caused by the Severe Acute Respiratory Syndrome Coronavirus type 2 (SARS-CoV-2), is the largest pandemic in modern history with very high infection rates and considerable mortality. The disease, which emerged in China’s Wuhan province, had its first reported case on December 29, 2019, and spread rapidly worldwide. On March 11, 2020, the World Health Organization (WHO) declared the COVID-19 outbreak a pandemic and global health emergency. Since the outbreak, efforts to develop COVID-19 vaccines, engineer new drugs, and evaluate existing ones for drug repurposing have been intensively undertaken to find ways to control this pandemic. COVID-19 therapeutic strategies aim to impair molecular pathways involved in the virus entrance and replication or interfere in the patients’ overreaction and immunopathology. Moreover, nanotechnology could be an approach to boost the activity of new drugs. Several COVID-19 vaccine candidates have received emergency-use or full authorization in one or more countries, and others are being developed and tested. This review assesses the different strategies currently proposed to control COVID-19 and the issues or limitations imposed on some approaches by the human and viral genetic variability.

https://doi.org/10.1590/1678-4685-gmb-2020-0452

Nutritional profile, bioactive compounds and antioxidant capacity of jatobá-da-mata (Hymenaea courbaril, var. stilbocarpa) by product
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Pereira Santos, Ana Carolina

; Martins Alves, Amanda

; Veloso Naves, Maria Margareth

; Reis Silva, Mara

Revista chilena de nutrición

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Jun 2020, Volume 47 Nº 3 Páginas 366 - 371

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

ABSTRACT Jatobá (Hymenaea sp.) is an arboreal legume native to the Brazilian Savannah (Cerrado) and its fruit has a high functional potential, but the jatobá-da-mata specie has been poorly explored. This study evaluated the nutritional profile, bioactive compounds and antioxidant capacity of jatobá-da-mata byproducts: pulp flour, fibrous pulp residue and sap. Jatobá fruits were pulped to obtain pulp flour and fibrous pulp residue, and the jatobá tree’s sap was obtained in a typical extraction location in the Cerrado (Brazilian Savannah). Fibrous pulp residue and pulp flour had high protein (11 and 12 g/100 g) and dietary fiber (49 and 44 g/100 g) content, respectively, and the fibrous residue showed the highest total and insoluble fibers, ash and vitamin C content. Regarding polyphenols, the fibrous residue showed a high concentration (775 mg GAE/100 g); an intermediate value in pulp flour (462 mg GAE/100 g); and considerable content in sap(181 mg GAE/100 g). Jatobá residue and pulp flour are suitable ingredients for the formulation of functional foods, and the sap is a promising non-caloric product with potential health benefits.

RESUMEN Jatobá (Hymenaea sp.) es una leguminosa arbórea originaria de la sabana brasileña y su fruto tiene un alto potencial funcional, pero la especie jatobá-da-mata ha sido poco explorada. El objetivo del estudio fue evaluar el perfil nutricional, compuestos bioactivos y capacidad antioxidante de subproductos del jatobá-da-mata: harina de la pulpa, residuo fibroso de la pulpa y la savia. Los frutos fueron despulpados para obtener la harina juntamente con el residuo fibroso de la pulpa, y la savia de la planta fue obtenida en un lugar exclusivo de extracción en el Cerrado (Sábana brasileña). El residuo fibroso y la harina de la pulpa contienen un alto contenido de proteína (11 y 12 g/100 g) y de fibra dietética (49 y 44 g/100 g), respectivamente, y el residuo fibroso mostró el mayor contenido de fibras totales y insolubles, cenizas y vitamina C. En cuanto a los polifenoles, el residuo fibroso presentó alta concentración (775 mg AGE/100 g); la harina de la pulpa, un valor intermedio (462 mg AGE/100 g); y la savia, un contenido considerable (181 mg AGE/100 g). El residuo fibroso y la harina de la pulpa son ingredientes adecuados en la formulación de alimentos funcionales, y la savia es un producto no calórico prometedor con potenciales beneficios a la salud.

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Preventing vertical HIV virus transmission: hospital care assessment
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Holzmann, Ana Paula Ferreira

; Silva, Carla Silvana de Oliveira e

; Soares, Janer Aparecida Silveira

; Vogt, Sibylle Emilie

; Alves, Carolina dos Reis

; Taminato, Mônica

; Barbosa, Dulce Aparecida

Revista Brasileira de Enfermagem

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2020, Volume 73 Nº 3 elocation e20190491

Resumo: En Es Pt | Texto: En Es Pt | PDF: En | PDF: Es | PDF: Pt

ABSTRACT Objectives: assess the implementation of actions to prevent vertical transmission of HIV. Methods: a retrospective cohort study conducted in two maternity hospitals in the city of Montes Claros, State of Minas Gerais. All women admitted for childbirth diagnosed with HIV and their respective newborns were included from 2014 to 2017. Data were collected from medical records and analyzed descriptively. Results: population consisted of 46 pairs of mothers and newborns. Management was considered inadequate in 30 cases of parturient/postpartum women (65.2%) and 14 cases of newborns (30.4%). The main reasons for inadequate maternal management were lack of pharmacological inhibition of lactation (53.3%) and counseling/consent for HIV testing (43.3%). For newborns, late onsetoffirst dose ofZidovudine (50.0%) and no prescriptionofNevirapine (28.6%). Conclusions: important prevention opportunities were missed, pointing to the need for improved care.

RESUMEN Objetivos: evaluar la implementación de acciones para prevenir la transmisión vertical del VIH. Métodos: estudio de cohorte retrospectivo realizado en dos hospitales de maternidad em la ciudad de Montes Claros, estado de Minas Gerais. Todas las mujeres ingresadas para el parto diagnosticadas con VIH y sus respectivos reciénnacidos se incluyeron entre 2014 y 2017. Los datos se recopilaron de los registros médicos y se analizaron descriptivamente. Resultados: la población consistió en 46 pares de madres y reciénnacidos. El manejo se consideró inadecuado en 30 casos de mujeres parturientas/posparto (65,2%) y 14 casos de reciénnacidos(30,4%). Las razones principales para el manejo materno inadecuado fueron: falta de inhibición farmacológica de lalactancia (53.3%) y asesoramiento/consentimiento para la prueba del VIH (43,3%). Para los reciénnacidos, inicio tardío de la primera dosis de zidovudina (50.0%) y sin prescripción de nevirapina (28,6%). Conclusiones: se perdieron importantes oportunidades de prevención, lo que indica la necesidad de una mejor atención.

RESUMO Objetivos: avaliar a implementação das ações de prevenção da transmissão vertical do HIV. Métodos: estudo de coorte retrospectivo, realizado em duas maternidades de Montes Claros, Minas Gerais. Foram incluídas todas as mulheres admitidas para o parto com diagnóstico de HIV e seus respectivos recém-nascidos, nos anos de 2014 a 2017. Os dados foram coletados de prontuários e analisados de forma descritiva. Resultados: a população foi composta por 46 pares de mães e recém-nascidos. O manejo foi considerado inadequado em 30 casos de parturientes/puérperas (65,2 %) e em 14 casos de recém-nascidos (30,4%). Os principais motivos para a inadequação do manejo materno foram: ausência da inibição farmacológica da lactação (53,3%) e do aconselhamento/consentimento na realização do exame anti-HIV (43,3%). Para os recém-nascidos, início tardio da primeira dose daZidovudina (50,0%) e não prescrição da Nevirapina (28,6%). Conclusões: oportunidades importantes de prevenção foram perdidas, apontando para a necessidade de melhoria da assistência.

https://doi.org/10.1590/0034-7167-2019-0491 25 downloads

Preventing vertical HIV virus transmission: hospital care assessment
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Holzmann, Ana Paula Ferreira

; Silva, Carla Silvana de Oliveira e

; Soares, Janer Aparecida Silveira

; Vogt, Sibylle Emilie

; Alves, Carolina dos Reis

; Taminato, Mônica

; Barbosa, Dulce Aparecida

Revista Brasileira de Enfermagem

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2020, Volume 73 Nº 3 elocation e20190491

Resumo: Pt En Es | Texto: Pt En Es | PDF: Pt | PDF: En | PDF: Es

https://doi.org/10.1590/0034-7167-2019-0491 2328 downloads

10.

Preparation of Syntactic Foams made from Green Polyethylene and Glass Microspheres: Morphological and Mechanical Characterization
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Cosse, Renato Lemos

; Morais, Ana Carolina Lemos de

; Silva, Lucas Rafael Carneiro da

; Carvalho, Laura Hecker de

; Reis Sobrinho, José Francisco dos

; Barbosa, Renata

; Alves, Tatianny Soares

Materials Research

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2019, Volume 22 elocation e20190035

Resumo: En | Texto: En | PDF: En

Polymeric syntactic foams are composites made from the mixture of Hollow Glass Microspheres (HGM) and polymer matrices. One of their main characteristics is their low density and the production of these composites using a matrix derived from renewable sources potentiates their development without neglecting sustainability. In this paper , the properties of High Density Polyethylene (HDPE)/HGM syntactic foams containing 1% and 5% w/w HGM and 5% w/w of a compatibilizer are assessed. The composites were prepared by two processing routes: single screw extruder and twin screw extruder. The morphology and mechanical properties (tensile and impact) of the syntactic foams thus manufactured were ascertained. Morphological analysis indicated that matrix/filler adhesion was poor for all samples and that the best HGM dispersions were obtained in twin screw extruded samples. Mechanical properties were affected by the processing route adopted and by the content of hollow glass microspheres added. Elastic modulus, tensile strength and strain were reduced by 20, 10 and 23%, respectively, in systems processed in a twin screw extruder. Impact strength was the exception, with an increase of more than 300%. Higher contents of hollow glass microspheres led to reductions in mechanical strength of the syntactic foams, varying from 5% for the elastic modulus to 50% for strain.

https://doi.org/10.1590/1980-5373-mr-2019-0035 673 downloads

11.

Longitudinalidade e formação profissional: fundamentos para o desempenho das equipes de saúde da família
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Alves, Carolina dos Reis

; Andrade, Mariléia Chaves

; Santos, Claudio Luis de Souza

Saúde em Debate

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Dez 2016, Volume 40 Nº 111 Páginas 268 - 278

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO Este artigo tem como objetivo avaliar o desempenho de equipes de saúde da família por meio do monitoramento dos indicadores de saúde contratualizados no Programa Nacional de Melhoria do Acesso e da Qualidade da Atenção Básica. Trata-se de estudo transversal, de cunho descritivo e abordagem quantitativa. Os resultados revelam que as equipes com desempenho satisfatório em todos os indicadores e em todos os anos analisados possuem maior tempo de implantação associado ao tempo de permanência do enfermeiro. Demonstram, também, que o tempo influencia diretamente o resultado, já que longitudinalidade e continuidade são atributos específicos da atenção primária construídos e estabelecidos com os usuários, o que favorece o estabelecimento do vínculo do usuário à equipe.

ABSTRACT This article aims to evaluate the performance of family health teams by monitoring of health indicators defined by the National Program for Access and Quality Improvement in Primary Care. It is a cross-sectional and descriptive study of quantitative approach. Results reveal that teams with satisfactory performance in all indicators during the analyzed yearshave greater deployment time associated with the nurse permanence in the team. They also demonstrate that time influences directly the result since longitudinality and continuity of primary care specific attributes are constructed and established together with users, favoring the creation of a liaison between user and team.

https://doi.org/10.1590/0103-1104201611121 1346 downloads

12.

Longitudinalidade e formação profissional: fundamentos para o desempenho das equipes de saúde da família
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Alves, Carolina dos Reis

; Andrade, Mariléia Chaves

; Santos, Claudio Luis de Souza

Saúde em Debate

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Dez 2016, Volume 40 Nº 111 Páginas 268 - 278

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/0103-1104201611121 254 downloads

13.

Prevalência de cefaleia em adolescentes e associação com uso de computador e jogos eletrônicos
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Xavier, Michelle Katherine Andrade

; Pitangui, Ana Carolina Rodarti

; Silva, Georgia Rodrigues Reis

; Oliveira, Valéria Mayaly Alves de

; Beltrão, Natália Barros

; Araújo, Rodrigo Cappato de

Ciência & Saúde Coletiva

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Nov 2015, Volume 20 Nº 11 Páginas 3477 - 3486

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Este estudo objetivou verificar a prevalência de cefaleia em adolescentes e sua associação com o uso excessivo de computador e jogos eletrônicos. A amostra foi composta por 954 adolescentes (14 a 19 anos), de ambos os sexos, que responderam ao questionário sobre uso de computadores e jogos eletrônicos, presença de cefaleia e atividade física. Foi utilizada a regressão logística binária e multinomial, com nível de significância de 5%. Evidenciou-se alta prevalência de cefaleia (80,6%) e elevado tempo de uso de dispositivos eletrônicos. O uso excessivo dos dispositivos eletrônicos mostrou-se fator de risco para cefaleia. Os sujeitos com idade entre 14 e 16 anos apresentaram menor chance de relatar a cefaleia. Em relação ao tipo, 17,9% apresentaram cefaleia do tipo tensional, 19,3% migrânea e 43,4% outros tipos de cefaleia. Os adolescentes com idade entre 14 e 16 anos apresentam menor chance de relatar a cefaleia do tipo tensional e de outros. Estar cursando o terceiro ano e usar excessivamente equipamentos digitais mostraram-se fatores de risco para cefaleia migrânea. Os resultados permitem concluir que o uso excessivo de dispositivos eletrônicos está associado à presença de cefaleia, principalmente do tipo migrânea.

The aim of this study was to determine the prevalence of headache in adolescents and its association with excessive use of electronic devices and games. The sample comprised 954 adolescents of both sexes (14 to 19 years) who answered a questionnaire about use of computers and electronic games, presence of headache and physical activity. The binary and multinomial logistic regression, with significance level of 5% was used for inferential analysis. The prevalence of headache was 80.6%. The excessive use of electronics devices proved to be a risk factor (OR = 1.21) for headache. Subjects aged between 14 and 16 years were less likely to report headache (OR = 0.64). Regarding classification, 17.9% of adolescents had tension-type headache, 19.3% had migraine and 43.4% other types of headache. The adolescents aged form 14 to 16 years had lower chance (OR ≤ 0.68) to report the tension-type headache and other types of headache. The excessive use of digital equipment, electronic games and attending the third year of high school proved to be risk factors for migraine-type development (OR ≥ 1.84). There was a high prevalence of headache in adolescents and high-time use of electronic devices. We observed an association between excessive use of electronic devices and the presence of headache, and this habit is considered a risk factor, especially for the development of migraine-type.

https://doi.org/10.1590/1413-812320152011.19272014 7666 downloads

14.

Prevalência de cefaleia em adolescentes e associação com uso de computador e jogos eletrônicos
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Xavier, Michelle Katherine Andrade

; Pitangui, Ana Carolina Rodarti

; Silva, Georgia Rodrigues Reis

; Oliveira, Valéria Mayaly Alves de

; Beltrão, Natália Barros

; Araújo, Rodrigo Cappato de

Ciência & Saúde Coletiva

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Nov 2015, Volume 20 Nº 11 Páginas 3477 - 3486

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/1413-812320152011.19272014 1416 downloads

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