RESUMO Introdução Lesão no menisco do joelho é uma lesão esportiva comum e a cirurgia minimamente invasiva sob artroscopia no joelho tornou-se um método ideal para tratar lesões no menisco. A reabilitação dessa cirurgia vem sendo aprimorada e vários estudos sobre os efeitos do exercício funcional no leque de tratamento ainda são inconclusivos. Objetivo Estudar os efeitos da reabilitação com exercício funcional em pacientes após a lesão esportiva do menisco. Métodos Foram selecionados 20 pacientes com lesão menisco-medial a serem operados, incluindo 8 homens e 12 mulheres. Divididos aleatoriamente em 2 grupos: grupo de treinamento neuromuscular e grupo de treinamento força (11). Sinais e sintomas foram avaliados antes do tratamento e 8 semanas após o tratamento, índices de score JOA e teste de marcha foram comparados, as diferenças do impacto da reabilitação em cada grupo foram avaliadas. Resultados Oito semanas após a reabilitação dos dois grupos, os escores do grupo de treinamento de força foram superiores aos do grupo neuromuscular, a diferença entre os grupos foi estatisticamente significante (P<0,05). Conclusão O exercício funcional acelera a recuperação das articulações, refletida no aumento da força dos músculos adjacentes. O efeito do treinamento muscular e articular na lesão do menisco pós-operatório é digno de reconhecimento. A baropodometria revelou distinções no padrão de marcha entre os diferentes métodos de reabilitação. Na perspectiva desta pesquisa, métodos de reabilitação combinados com exercícios proprioceptivos são complementares. Nível de evidência II; Estudos Terapêuticos - Investigação de Resultados.

ABSTRACT Introduction Knee meniscus injury is a common sports injury, and minimally invasive surgery under knee arthroscopy has become an ideal method to treat meniscus injuries. This surgery rehabilitation has been improved, and several studies on the effects of functional exercise in the range of treatment are still inconclusive. Objective Study the functional exercise rehabilitation effects in patients after sports meniscus injury. Methods Twenty patients with meniscus-medial injury being operated on were selected, including eight men and 12 women. They were randomly divided into neuromuscular and strength training groups (11). Signs and symptoms were assessed before and eight weeks after treatment. JOA score indices and gait tests were compared. The impact of rehabilitation differences was evaluated in each group. Results Eight weeks after rehabilitation in both groups, the scores of the strength training group were higher than the neuromuscular group; the difference between the groups was statistically significant (P<0.05). Conclusion Functional exercise accelerates joint recovery, reflected in increased strength of adjacent muscles. The muscle and joint training effects on postoperative meniscus injury are worthy of recognition. The baropodometry revealed distinctions in walking patterns between different rehabilitation methods. From the perspective of this research, rehabilitation methods combined with proprioceptive exercises are complementary. Evidence Level II; Therapeutic Studies - Investigating the result.

RESUMEN Introducción La lesión de menisco de la rodilla es una lesión deportiva común y la cirugía mínimamente invasiva por artroscopia de rodilla se ha convertido en un método ideal para tratar las lesiones de menisco. La rehabilitación de esta cirugía ha sido mejorada y varios estudios sobre los efectos del ejercicio funcional en el rango de tratamiento aún no son concluyentes. Objetivo Estudiar los efectos de la rehabilitación con ejercicio funcional en pacientes tras una lesión de menisco deportiva. Métodos Se seleccionaron 20 pacientes con lesión de menisco-medial para ser operados, incluyendo 8 hombres y 12 mujeres. Se dividieron aleatoriamente en 2 grupos: grupo de entrenamiento neuromuscular y grupo de entrenamiento de fuerza (11). Se evaluaron los signos y síntomas antes del tratamiento y 8 semanas después del mismo, se compararon los índices de puntuación JOA y la prueba de marcha, y se evaluaron las diferencias del impacto de la rehabilitación en cada grupo. Resultados Ocho semanas después de la rehabilitación para ambos grupos, las puntuaciones del grupo de entrenamiento de fuerza fueron mayores que las del grupo neuromuscular, la diferencia entre los grupos fue estadísticamente significativa (P<0,05). Conclusión El ejercicio funcional acelera la recuperación de la articulación, lo que se refleja en el aumento de la fuerza de los músculos adyacentes. El efecto del entrenamiento muscular y articular en la lesión postoperatoria del menisco es digno de reconocimiento. La baropodometría reveló diferencias en el patrón de la marcha entre los diferentes métodos de rehabilitación. Desde la perspectiva de esta investigación, los métodos de rehabilitación combinados con los ejercicios propioceptivos son complementarios. Nivel de evidencia II; Estudios terapéuticos - Investigación de resultados.

ABSTRACT Background: While sarcopenia is an important clinical finding in individuals diagnosed with chronic heart failure (CHF), efforts to identify a reliable biomarker capable of predicting the overall muscular and functional decline in CHF patients have been unsuccessful to date. Objectives: The objectives of this study were to study the diagnostic utility of MicroRNA (miRNA)-1-3p as a predictor of sarcopenia status in individuals diagnosed with CHF. Methods: In total, 80 individuals with heart failure exhibiting a left ventricular ejection fraction < 50% were enrolled in this study. All patients were analyzed to assess miR-1-3p expression levels, with body composition being evaluated through dual-energy X-ray absorptiometry and sarcopenia being defined based on the sum of appendicular lean muscle mass (ALM) divided by height in meters squared and handgrip strength (HGS). In addition, the activation of the Akt/mTOR signaling pathway was evaluated in these individuals. Results: In total, 40 of the enrolled patients (50%) exhibited sarcopenia. Sarcopenic patients presented with increased miR-1-3p expression levels as compared to non-sarcopenic individuals (1.69 ± 0.132 vs. 1.22 ± 0.106; p < 0.05). With respect to sarcopenic indices, appendicular skeletal mass index was most strongly correlated with miR-1-3p expression, which was also strongly correlated with HGS. High levels of Akt/mTOR signaling pathway components were expressed in sarcopenic individuals, highlighting a significant relationship between miR-1-3p activity and signaling through this pathway. Moreover, miR-1-3p was identified as a specific marker for sarcopenia in individuals with CHF. Conclusion: These results suggest that circulating miR-1-3p levels are related to Akt/mTOR pathway activation and can offer valuable insight into the overall physical capacity and muscular integrity of CHF patients as a predictor of sarcopenia.

ABSTRACT Salt-tolerant ‘Chuanqiao No.1’ and salt-sensitive ‘Chuanqiao No.2’ Tartary buckwheat (Fagopyrum tataricum (L.) Gaertn.) were used as materials. Effects of ethephon on physiological characteristics of Tartary buckwheat under salt stress were studied by different concentrations of ethephon (ETH) under 150 mM NaCl stress. Ethephon treatment could improve seed germination rate of both varieties under salt stress, and the effect of ethephon treatment on salt-sensitive variety was better. Ethephon treatment could improve physiological characteristics of Tartary buckwheat seedlings under salt stress, and appropriate concentrations of ETH root treatment in salt-tolerant and salt-sensitive variety were 1.0 and 1.5 mM, and for ETH spraying were 0.4 and 0.6 mM. The effect of ETH spraying on improving physiological characteristics of Tartary buckwheat under salt stress was better than that of ETH root treatment. Salt tolerance gene FtNHX1 reached its maximum expression level at 24 h, which was increased by 277.77% and 251.17% in salt-tolerant and salt-sensitive variety compared with salt stress under ETH root treatment, while under ETH spraying treatment, which was increased by 232.39% and 190.91% in salt-tolerant and salt-sensitive variety compared with salt stress. Salt tolerance gene FtSOS1 reached its maximum expression levels at 12 h, which was increased by 60.94% and 98.75% in salt-tolerant and salt- sensitive variety compared with salt stress under ETH root treatment, while under ETH spraying treatment, which was increased by 35.98% and 67.63% in salt-tolerant and salt-sensitive variety compared with salt stress.

Abstract Photoperiod is an important environmental factor affecting animal physiological function. Melatonin is an endogenous hormone that plays an important role in circadian and seasonal (or cyclical) rhythms and seasonal reproduction in mammals. To investigate the effects of melatonin on the reproductive performance of adult male mice under different photoperiods, sixty mice were randomly allotted to six groups: control (Light Dark, 12 L:12 D), control plus melatonin (MLD, 12 L:12 D), 24-hour continuous light (LL, 24 L:0 D), 24-hour continuous light plus melatonin (MLL 24 L:0 D), constant darkness (DD, 0 L:24 D), and constant darkness plus melatonin (MDD, 0 L:24 D). Normal saline (100 μL) was injected into the LD, LL, and DD groups at noon each day; the MLD, MLL, and MDD groups were injected with melatonin (1 mg/mL; 2 mg/kg·body weigh). After 24 hours of prolonged light exposure, testis morphology decreased, convoluted seminiferous tubules became sparse, the diameter of convoluted seminiferous tubules decreased, and the level of sex hormones decreased. After the administration of exogenous melatonin, testicular morphology and sex hormone levels decreased in the MLD group under normal light conditions. In the MLL group, the testicular tissue morphology returned to normal, the diameter of convoluted tubules increased, the hormone levels of LH (Luteinizing hormone) and MTL (melatonin) significantly increased (P<0.05), and th0e gene expressions of LHβ and Mtnr1A (Melatonin receptors 1A) increased. There was almost no difference in the MDD group under continuous darkness. In conclusion, melatonin can damage the reproductive performance of male mice under normal light conditions, while exogenous melatonin can alleviate and protect the testicular injury of male mice under continuous light conditions.

ABSTRACT Purpose: The active melanocytes in the skin were affected by hormones and ultraviolet (UV) irradiation. Licorice zinc has a whitening effect, which may have a prominent potential in the treatment of pigmented skin disease. Methods: Modeling chloasma Balb/c mice by daily progesterone injection (15 mg/kg) and ultraviolet B (UVB) irradiation (λ = 312 nm, 2 h/day) for 30 days. Then, mice were given 0.65, 1.3, and 2.6 (g/kg) of licorice zinc and tranexamic acid 250 mg daily by oral administration for 14 days, respectively. Hematoxylin and eosin and Fontana-Masson staining, and Western blotting (WB) were performed to test the inhibitory of melanogenesis and activation of c-Jun-N-terminal (JNK)/p38 mitogen-activated protein kinases (MAPK) for licorice zinc. Melanogenesis was induced by α-melanocyte-stimulating hormone in vitro. Cell counting kit-8, melanin content determination, and WB were performed to verify the inhibitory effect of licorice zinc on melanogenesis. Results: The present study showed that licorice zinc decreased melanin formation, cutaneous tissue injury, and the phosphorylation of JNK and P38MAPK, which was caused by UVB irradiation in vivo. In vitro, licorice zinc showed opposite effects from JNK/p38 activator. Meanwhile, tyrosinase-related protein-1, tyrosinase, and microphthalmia-associated transcription factor were decreased too. Conclusions: Licorice zinc induced a decrease in melanin synthesis by inhibiting the JNK and the P38MAPK signaling pathway, suggesting licorice zinc is a potential agent of anti-chloasma.

Abstract Background Osteoporosis (OP) is common in patients with chronic obstructive pulmonary disease (COPD). The relationship between OP and COPD has been primarily studied in male patients, and few reports are available in postmenopausal women. Objective The purpose of this study was to investigate the association between bone mineral density (BMD) and COPD in postmenopausal women. Methods This cross-sectional study included 133 clinically stable female ex-smokers with confirmed COPD, and 31 age-matched “ex-smoker” female controls. We analyzed groups according to their airway obstruction category. BMD was measured on dual-energy X-ray absorptiometry images of the left femoral neck. Results Patients with COPD had lower T-scores and higher prevalence of osteopenia/OP than the control group. In the COPD group, the airway obstruction category was significantly associated with the T-score after adjustment for confounders. Multivariate logistic regression analysis showed COPD was an independent marker for increased risk of osteopenia/OP in postmenopausal women. Conclusions COPD and airway obstruction category were strongly related to BMD. Postmenopausal women with COPD, especially those with severe airway obstruction, had a higher prevalence rate and a higher risk of osteopenia and OP than female controls without COPD.

Resumo Fundamento: A doença arterial coronariana (DAC) e a osteoporose são doenças comuns em mulheres pós-menopausa. Tanto em estudos transversais como em estudos epidemiológicos longitudinais, a massa óssea diminuída foi relacionada à frequência aumentada de DAC. No entanto, dados disponíveis sobre a relação entre densidade mineral óssea (DMO) e gravidade das lesões coronarianas são limitados. Objetivo: Investigar a associação entre DMO e gravidade das lesões coronarianas avaliadas pelo escore de Gensini em mulheres pós-menopausa. Métodos: Este estudo incluiu 122 mulheres pós-menopausa diagnosticadas com DAC. As pacientes foram divididas em dois grupos de acordo com a gravidade das lesões coronarianas avaliada pelo escore de Gensini - pacientes com lesões coronarianas leves (escore de Gensini < 25) e pacientes com lesões coronarianas graves (escore de Gensini ≥ 25). A densidade mineral do colo femoral foi medida por absorção de raios-X de dupla energia (DXA). Resultados: O estudo incluiu mulheres pós-menopausa com idade de 64,31 ± 4,71 anos, 85 delas (69,7%) com lesões coronarianas graves. Pacientes com lesões coronarianas graves apresentaram um escore T mais elevado que aquelas com lesões coronarianas leves no colo femoral (p < 0,05). O escore T médio foi -0,84 ± 1,01 no grupo com lesões leves, e -1,42 ± 1,39 no grupo com lesões graves (p < 0,05). A análise de regressão logística multivariada mostrou que a osteopenia-osteoporose no colo femoral (odds ratio 2,73; intervalo de confiança de 95% 1,06 - 6,13) esteve associada com um risco aumentado de se desenvolver lesões coronarianas graves. O modelo de regressão múltipla mostrou que os escores T (b = -0,407; EP= 0,151; p = 0,007) foram preditores independentes do escore de Gensini. Conclusão: Encontrou-se uma relação significativa entre a gravidade das lesões coronarianas e a DMO em mulheres pós-menopausa. DMO, uma técnica de baixo custo que envolve mínima exposição à radiação, e amplamente utilizada no rastreamento de osteoporose, é um marcador promissor da gravidade de lesões coronarianas graves.

Abstract Background: Coronary artery disease (CAD) and osteoporosis (OP) are common diseases in postmenopausal women. In both cross-sectional and longitudinal epidemiologic studies, low bone mass has been related to increased frequency of CAD. However, available data on the relationship between bone mineral density (BMD) and severity of coronary lesions is limited. Objective: To investigate association between the BMD and severity of coronary lesions assessed by Gensini score in postmenopausal women. Methods: This study included 122 postmenopausal women who were diagnosed with CAD. These patients were divided into two groups according to the severity of coronary lesions assessed by the Gensini score - patients with mild coronary lesions (Gensini score < 25) and patients with severe coronary lesions (Gensini score ≥ 25). Femoral neck mineral density was measured with dual energy X-ray absorptiometry (DXA). Results: The study included postmenopausal women aged 64.31 ± 4.71 years, 85 of whom (69.7%) exhibited severe coronary lesions. Participants with severe coronary lesions had a significantly higher T score than did those with mild coronary lesions at the femoral neck (p < 0.05). The mean T-score was −0.84 ± 1.01 in mild coronary lesions group, −1.42 ± 1.39 in severe coronary lesions group (p < 0.05). Multivariable logistic regression analysis showed that osteopenia-osteoporosis at the Femoral neck (odds ratio 2.73; 95% confidence interval 1.06 to 6.13) was associated with an increased risk of developing severe coronary lesions. The multiple regression model showed that T-scores (b = −0.407, SE = 0.151, p=0.007) were the independent predictors of Gensini score. Conclusion: The relationship between severity of coronary lesions and BMD was significant in postmenopausal women. BMD, a low-cost technique involving minimal radiation exposure, widely used for osteoporosis screening, is a promising marker of severity of coronary lesions.

Previous studies have indicated that propofol has immunomodulatory and antioxidative properties. However, the renoprotection effect and the precise mechanisms of propofol in sepsis-induced renal injury remain unclear. The purpose of the present study was to investigate the role of miR-290-5p/CCL-2 signaling in septic mice treatment with propofol. Mice were treated with propofol (50 mg/kg) twice within 24 h. Survival outcome was monitored within 48 h. The mRNA and protein levels were assayed by qRT-PCR and western blotting, respectively. Mouse podocytes (MPC5) were treated with lipopolysaccharide (LPS) to establish the cell model in vitro. The proliferation of MPC5 was monitored using the MTS assay. Cell apoptosis was analyzed by flow cytometry. Propofol improved survival outcome and alleviated acute kidney injury in cecal ligation and puncture-operated mice. Propofol increased miR-290-5p expression and decreased CCL-2 and inflammatory cytokines levels in the kidney for septic mice. We found that miR-290-5p was a direct regulator of CCL-2 in MPC5. Propofol could abrogate LPS-induced growth inhibition and apoptosis in MPC5. Meanwhile, propofol inhibited CCL-2 expression in LPS-treated MPC5, however, knockdown of miR-290-5p abrogated the inhibitory effect propofol on the mRNA and protein expressions of CCL-2. Propofol could serve as an effective therapeutic medication to suppress sepsis-induced renal injury in vivo and in vitro by regulating the miR-290-5p/CCL-2 signaling pathway.

Single crystal of rare-earth polyphosphate Tm(PO3)3 has been grown under high temperature molten-salt method and structurally characterized by single crystal X-ray diffraction analysis. Using the four-dimensional superspace formalism for aperiodic structures, we performed the crystal structure refinement of Tm(PO3)3 as (3+1)-dimensional incommensurately modulated structure with monoclinic superspace group C2/c(0, 0.358, 0)s0 and α = 14.0620 (12) Å, b = 6.6612 (6) Å, c = 10.0191 (9) Å, β = 127.6043 (9)°, V = 743.51 (11) ų, Z = 4, Mr = 405.8, Dc = 3.626 g/cm³, F(000) = 744, μ(MoKα) = 12.60 mm'¹, R = 0.048 and ωR = 0.050. The structure features infinite chains of corner-sharing PO4 tetrahedra which are affected by positional modulation running along the b-axis. The final structure model was reasonable and did not show any unusual features.

Justificativa e objetivo: O presente estudo teve como objetivo avaliar se a profundidade de inserção de cateter em veia subclávia (VSC) direita pode ser prevista de forma confiável pelas distâncias do local de inserção na VSC até a incisura clavicular ipsilateral (I-IC), passando diretamente pela parte superior do arco da VSC ou da clavícula (denominadas i-T-IC e i-C-IC, respectivamente). Método: No total, 70 cateterismos de VSC foram estudados. As distâncias I-IC, I-T-IC e I-C-IC de cada caso foram mensuradas após a inserção do cateter guiada por ultrassom. O comprimento do cateter entre o local de inserção e a incisura clavicular ipsilateral (L) foi calculado por meio de radiografia. Resultados: As diferenças em centímetros de L em relação às distâncias I-T-IC, I-C-IC e I-IC foram de 0,14±0,53; 2,19±1,17 e 0,45±0,68 respectivamente. A média de I-IC foi significativamente menor que L, enquanto a média de I-C-IC foi significativamente maior. A análise de regressão linear forneceu a seguinte fórmula: Comprimento previsto da inserção de cateter em VSC (cm) = -0,037 + 0,036 × Altura (cm) + 0,903 × I-T-IC (cm) (r2 ajustado = 0,64). Conclusão: A distância I-T-IC pode ser um preditivo confiável do comprimento de inserção ideal para canulação em VSC direita.

Background and objective: The present study aimed to evaluate whether right subclavian vein (SCV) catheter insertion depth can be predicted reliably by the distances from the SCV insertion site to the ipsilateral clavicular notch directly (denoted as I-IC), via the top of the SCV arch, or via the clavicle (denoted as I-T-IC and I-C-IC, respectively). Method: In total, 70 SCV catheterizations were studied. The I-IC, I-T-IC, and I-C-IC distances in each case were measured after ultrasound-guided SCV catheter insertion. The actual length of the catheter between the insertion site and the ipsilateral clavicular notch, denoted as L, was calculated by using chest X-ray. Results: L differed from the I-T-IC, I-C-IC, and I-IC distances by 0.14±0.53, 2.19±1.17, and -0.45 ±0.68 cm, respectively. The mean I-T-IC distance was the most similar to the mean L (intraclass correlation coefficient = 0.89). The mean I-IC was significantly shorter than L, while the mean I-C-IC was significantly longer. Linear regression analysis provided the following formula: Predicted SCV catheter insertion length (cm) = -0.037 + 0.036 × Height (cm) + 0.903 × I-T-IC (cm) (adjusted r2 =0.64). Conclusion: The I-T-IC distance may be a reliable bedside predictor of the optimal insertion length for a right SCV cannulation.

Introducción y objetivo: El presente estudio tuvo como objetivo evaluar si la profundidad de inserción de catéter en vena subclavia (VSC) derecha puede ser prevista de forma confiable por las distancias del lugar de inserción en la VSC hasta la incisión clavicular ipsilateral (denominada I-IC), pasando directamente por la parte superior del arco de la VSC o de la clavícula (denominadas I-T-IC y I-C-IC, respectivamente). Método: En total se estudiaron 70 cateterismos de VSC. Las distancias I-IC, I-T-IC e I-C-IC de cada caso fueron medidas después de la inserción del catéter guiada por ultrasonido. La extensión del catéter entre la región de inserción y la incisión clavicular ipsilateral, denominada L, fue calculada por medio de radiografía. Resultados: Las diferencias en centímetros de L con relación a las distancias I-I- IC, I-C-IC e I-IC fueron de 0,14±0,53, 2,19±1,17 y 0,45±0,68, respectivamente. La media de I-IC fue significativamente menor que L, mientras que la media de I-C-IC fue significativamente mayor. El análisis de regresión linear suministró la siguiente fórmula: Extensión prevista de la inserción de catéter en VSC (cm) = -0,037 + 0,036 × altura (cm) + 0,903 × I-T-IC (cm) (r2 ajustado = 0,64). Conclusión: La distancia I-T-IC puede ser un predictor confiable de la extensión de la inserción ideal para la canalización en la VSC derecha.

OBJECTIVE: To determine how data on water source quality affect assessments of progress towards the 2015 Millennium Development Goal (MDG) target on access to safe drinking-water. METHODS: Data from five countries on whether drinking-water sources complied with World Health Organization water quality guidelines on contamination with thermotolerant coliform bacteria, arsenic, fluoride and nitrates in 2004 and 2005 were obtained from the Rapid Assessment of Drinking-Water Quality project. These data were used to adjust estimates of the proportion of the population with access to safe drinking-water at the MDG baseline in 1990 and in 2008 made by the Joint Monitoring Programme for Water Supply and Sanitation, which classified all improved sources as safe. FINDINGS: Taking account of data on water source quality resulted in substantially lower estimates of the percentage of the population with access to safe drinking-water in 2008 in four of the five study countries: the absolute reduction was 11% in Ethiopia, 16% in Nicaragua, 15% in Nigeria and 7% in Tajikistan. There was only a slight reduction in Jordan. Microbial contamination was more common than chemical contamination. CONCLUSION: The criterion used by the MDG indicator to determine whether a water source is safe can lead to substantial overestimates of the population with access to safe drinking-water and, consequently, also overestimates the progress made towards the 2015 MDG target. Monitoring drinking-water supplies by recording both access to water sources and their safety would be a substantial improvement.

OBJETIVO: Determinar cómo afectan los datos sobre la calidad de las fuentes de agua a las evaluaciones del progreso hacia la meta de los Objetivos de Desarrollo del Milenio (ODM) sobre el acceso al agua potable segura. MÉTODOS: A través del proyecto Evaluación rápida de la calidad del agua potable se obtuvieron los datos sobre la adecuación de las fuentes de agua de cinco países a las directrices de calidad del agua de la Organización Mundial de la Salud en cuanto a contaminación por bacterias coliformes termorresistentes, arsénico, fluoruro y nitratos en 2004 y 2005. Estos datos se emplearon para ajustar los cálculos sobre la proporción de la población con acceso al agua potable segura en la línea de referencia del ODM de 1990 y de 2008 realizados por el Programa conjunto de vigilancia del abastecimiento de agua y el saneamiento, que clasificó todas las fuentes mejoradas como seguras. RESULTADOS: La inclusión de los datos sobre la calidad de la fuente de agua se tradujo en unas estimaciones sustancialmente menores del porcentaje de población con acceso al agua potable segura en 2008 en cuatro de los cinco países estudiados: la reducción absoluta fue de un 11% en Etiopía, un 16% en Nicaragua, un 15% en Nigeria y un 7% en Tayikistán. En Jordania sólo se apreció una disminución leve. La contaminación microbiana fue más frecuente que la contaminación química. CONCLUSIÓN: Los criterios empleados por el indicador del ODM para determinar si una fuente de agua es segura pueden comportar una sobreestimación considerable de la población con acceso al agua potable segura y, en consecuencia, una sobrevaloración del progreso dentro de la meta del ODM para 2015. La supervisión de los suministros de agua potable teniendo en consideración tanto el acceso a las fuentes de agua como su seguridad constituiría una mejora significativa.

OBJECTIF: Déterminer comment les données sur la qualité des sources d'eau affectent les évaluations de la progression vers l'accès à l'eau potable fixé par l'objectif du Millénaire pour le développement 2015 (OMD). MÉTHODES: On a extrait du projet Évaluation rapide de la qualité de l'eau potable les données de cinq pays relatives au fait que les sources d'eau potable étaient conformes aux directives de la qualité de l'eau de l'Organisation mondiale de la Santé en matière de contamination par des bactéries coliformes thermotolérantes, d'arsenic, de fluorure et de nitrates dans les années 2004 et 2005. Ces données ont été utilisées pour ajuster les estimations de la proportion de la population ayant accès à l'eau potable en 1990 et en 2008, années de référence de l'OMD, effectuées par le Programme conjoint de suivi de l'approvisionnement et de l'assainissement de l'eau, qui qualifiait de sûres toutes les sources améliorées. RÉSULTATS: Tenir compte des données sur la qualité des sources d'eau a conduit à des estimations nettement inférieures du pourcentage de la population ayant accès à l'eau potable en 2008 dans quatre des cinq pays étudiés: la réduction absolue était de 11% en Éthiopie, 16% au Nicaragua, 15% au Nigeria et 7% au Tadjikistan. Il n'y avait qu'une légère diminution en Jordanie. La contamination microbienne était plus fréquente que la contamination chimique. CONCLUSION: Le critère utilisé par l'indicateur OMD pour déterminer si une source d'eau est sûre peut entraîner des surestimations importantes de la population ayant accès à l'eau potable et, par conséquent, également des surestimations des progrès accomplis vers les résultats visés par l'OMD 2015. Faire le suivi de l'approvisionnement en eau potable, en contrôlant à la fois l'accès aux sources d'eau et leur sûreté, représenterait une amélioration importante.