Objectives To compare the effect of the consumption of buriti oil and soybean oil on the metabolism of rats under stress induced by iron overload.Materials and methods A total of 28 rats were randomized into control groups who consumed diet added of soybean (CS) or buriti oil (CB) and gavage with saline and two experimental groups who consumed diet added of soybean (ES) or buriti oil (EB) and daily gavage with iron II sulfate as stress inducer. The fatty acid profile of diets was analyzed. Body weight and diet consumption were evaluated every two days. The lipid profile and liver weight of animals were evaluated at the end of the experiment.Results Diet added of soybean oil showed higher percentage of polyunsaturated fatty acids (45.6%) and diet with buriti oil was rich in monounsaturated fatty acids (66.9%). There were no differences in food intake, total cholesterol, HDL-cholesterol and LDL-cholesterol among groups (p > 0.05). However, animals fed with diet supplemented with buriti oil showed intermediate triglyceride levels (CB: 65 mg/dL; EB: 68.7 mg/dL) compared to ES group (102.5 mg/dL). The liver of rats from the CS group had higher weight (2.06 ± 0.2 g) compared to the CB group (1.56 ± 0.1 g).Conclusion Buriti oil consumption was able to minimize some changes related to iron overload.

RESUMOMucuna pruriens (MP) tem sido comercializada como suplemento para emagrecimento mesmo sem comprovação científica. Este estudo objetiva avaliar o efeito da MP associada ao treinamento resistido sobre parâmetros murinométricos e consumo alimentar em ratos. Os animais foram randomizados nos grupos: controle sedentário e treinado, MP sedentário e treinado. Os treinados executaram protocolo de saltos e os suplementados receberam 250 mg de MP/kg/dia via gavagem. O consumo alimentar e peso corporal foram avaliados semanalmente e medidas murinométricas ao final do protocolo. Não houve alterações no consumo alimentar (147 a 180 g), peso (341 a 368 g), comprimento (entre 24,6 e 25,5 cm), circunferências torácica (de 14,1 a 16,2 cm) e abdominal (variação de 14,5 a 15,8 cm), índice de massa corporal (entre 0,53 e 0,56 g/cm2) e índice de Lee (entre 4,5 e 4,8 cm3). Suplementação de MP associada ao exercício não altera consumo alimentar, peso e medidas murinométricas em ratos.

ABSTRACTMucuna pruriens(mp) has been marketed as a supplement for weight loss even without scientific proof. this study aims to evaluate the effect of mp supplementation associated with resistance training on murinometric parameters and food consumption in rats. animals were randomized into sedentary and control groups, supplemented with mp or not. trained animals performed the jump protocol and received the mp supplementation (250 mg/kg/day) by gavage. food consumption and body weight were assessed weekly and murinometric parameters, at the end of the protocol. there were no changes in food intake (147 - 180 g), weight (341 - 368 g), length (24.6 - 25.5 cm), chest (14.1 - 16.2 cm) and abdominal circumferences (14.5 - 15.8 cm), body mass index (0.53 - 0.56 g/cm2) and lee index (4.5 - 4.8 g/cm3). mp supplementation during exercise does not alter food intake, weight and murinometric measurements in rats.

A fosseta de papila do nervo óptico e o microburaco macular são duas patologias raras, cuja probabilidade de coexistência se torna extremamente baixa, embora não haja relação fisiopatológica entre ambas, descreveremos um caso de associação das mesmas, acometendo comumente um olho, a fim de analisar as manifestações clínicas, os exames de OCT, angiografia, retinografia, biomocroscopia, o tratamento e a correlação entre ambas patologias.

Optic disc pit and macular microhole are two rare pathologies with an extremely low likelihood of coexistence, this paper will report an association of both pathologies in the same eye with the purpose of analyzing clinical manifestations, tests, angiography, OCT, retinography, biomocroscopy, treatment outcome and the connection between the optic disc pit and macular microhole.