Abstract The disease coronavirus COVID-19 has been the cause of millions of deaths worldwide. Among the proteins of SARS-CoV-2, non-structural protein 12 (NSP12) plays a key role during COVID infection and is part of the RNA-dependent RNA polymerase complex. The monitoring of NSP12 polymorphisms is extremely important for the design of new antiviral drugs and monitoring of viral evolution. This study analyzed the NSP12 mutations detected in circulating SARS-CoV-2 during the years 2020 to 2022 in the population of the city of Manaus, Amazonas, Brazil. The most frequent mutations found were P323L and G671S. Reports in the literature indicate that these mutations are related to transmissibility efficiency, which may have contributed to the extremely high numbers of cases in this location. In addition, two mutations described here (E796D and R914K) are close and have RMSD that is similar to the mutations M794V and N911K, which have been described in the literature as influential on the performance of the NSP12 enzyme. These data demonstrate the need to monitor the emergence of new mutations in NSP12 in order to better understand their consequences for the treatments currently used and in the design of new drugs. COVID19 19 COVID-1 worldwide SARSCoV2, SARSCoV2 SARSCoV SARS CoV 2, 2 nonstructural non structural 1 NSP (NSP12 RNAdependent dependent complex NSP1 evolution SARS-CoV- 202 Manaus Amazonas Brazil PL P L G671S GS G S efficiency location addition E796D ED E D R914K RK R K MV M V N911K NK N enzyme COVID1 COVID- (NSP1 SARS-CoV 20 (NSP

Organophosphates are prevalent in agrochemicals and chemical warfare agents, posing significant health and safety concerns. These compounds are known for their high chemical stability and to address this issue, nucleophilic catalysts have emerged as a promising solution for their degradation. Herein, we focus on a novel material created through the combined effects of imidazole and crumpled graphene (CG) to develop a nanocatalyst for the neutralization (i.e., degradation) of organophosphates (OPs). The strategy involves the covalent functionalization of CG with imidazole groups without disrupting the three-dimensional structure of CG. This unique combination results in a synergistic effect between neighboring imidazole groups within CG, significantly enhancing the catalytic performance. The catalytic increment (kCAT/kH2O) achieved is in the order of 104, demonstrating the remarkable efficiency of this catalyst. The pioneering and promising use of functionalized CG for addressing concerns with chemical security can boost and be broadened to other applications. agents issue degradation Herein (CG i.e., ie i e (i.e. OPs. OPs . (OPs) threedimensional three dimensional performance kCAT/kH2O kCATkH2O kCATkHO kCAT kH2O kH O (kCAT/kH2O 104 catalyst applications i.e. (i.e (OPs kCATkH kHO 10 i.e 1

ABSTRACT Introduction: The emergence of orthodontic aligners has provided an aesthetic and comfortable option for orthodontic treatment. However, the encapsulated design of the aligners can influence the masticatory muscles, and might compromise safe treatment. Objective: This preliminary longitudinal study aimed to investigate whether the use of orthodontic aligners affects the biting force and myoelectric activity of the superficial masseter and anterior temporal muscles. Methods: Ten subjects participated in the study and underwent treatment during an 8-month follow-up period. The root mean square (RMS), the median power frequency (MPF) of the surface electromyography (sEMG) signals, and the biting force (kgf) were recorded and normalized relative to the pretreatment condition. The data were analyzed by repeated-measure analysis of variance (ANOVA), with the significance level set at 5%. Results: Both the superficial masseter and the anterior temporal muscles presented an increase in sEMG signal activity during the treatment, with a marked increase in the latter compared to the former (p<0.05). Moreover, a significant decrease in bite force was evidenced (p<0.05). Conclusions: This preliminary study observed that the orthodontic aligners affected the muscle recruitment pattern of masticatory muscles, and reduced biting performance during the 8-month follow-up period. Introduction However Objective Methods 8month month 8 followup follow up period RMS, RMS , (RMS) MPF (MPF (sEMG signals kgf (kgf condition repeatedmeasure repeated measure ANOVA, ANOVA (ANOVA) 5 5% Results p<0.05. p005 p p<0.05 . 0 05 (p<0.05) Moreover Conclusions (RMS (ANOVA p00 p<0.0 (p<0.05 p0 p<0. (p<0.0 p<0 (p<0. p< (p<0 (p< (p

RESUMO Introdução: O surgimento dos alinhadores ortodônticos tem proporcionado uma opção estética e confortável para o tratamento ortodôntico. No entanto, o design encapsulado dos alinhadores pode influenciar os músculos mastigatórios e comprometer a segurança do tratamento. Objetivo: Este estudo longitudinal preliminar teve como objetivo investigar se o uso de alinhadores ortodônticos afeta a força de mordida e a atividade mioelétrica dos músculos masseter superficial e temporal anterior. Métodos: Dez indivíduos participaram do estudo e foram submetidos a tratamento durante um período de acompanhamento de 8 meses. A raiz quadrada média (RMS), a frequência mediana de potência (FMP) dos sinais de superfície da eletromiografia (sEMG) e a força de mordida (kgf) foram registradas e normalizadas em relação à condição de pré-tratamento. Os dados foram analisados por análise de variância para medidas repetidas (ANOVA), com nível de significância estabelecido em 5%. Resultados: Tanto o masseter superficial quanto o temporal anterior apresentaram aumento da atividade do sinal sEMG durante o tratamento, com aumento acentuado desse último em comparação ao primeiro (p<0,05). Além disso, foi evidenciada uma diminuição significativa da força de mordida (p<0,05). Conclusões: Esse estudo preliminar observou que os alinhadores ortodônticos afetaram o padrão de recrutamento muscular dos músculos mastigatórios e reduziram o desempenho da mordida durante o período de acompanhamento de oito meses. Introdução ortodôntico entanto Objetivo Métodos meses RMS, RMS , (RMS) FMP (FMP (sEMG kgf (kgf prétratamento. prétratamento pré pré-tratamento ANOVA, ANOVA (ANOVA) 5 5% Resultados p<0,05. p005 p p<0,05 . 0 05 (p<0,05) disso Conclusões (RMS (ANOVA p00 p<0,0 (p<0,05 p0 p<0, (p<0,0 p<0 (p<0, p< (p<0 (p< (p

RESUMO O Consultório LGBT na cidade de Macaé, estado do Rio de Janeiro, funciona diariamente para o cuidado em saúde de pessoas LGBTQIA+. Esse serviço integra uma rede que conta com o Hospital Universitário Pedro Ernesto e a clínica da Casa de Convivência. O atendimento tem contemplado, predominantemente, as pessoas travestis e transexuais. O objetivo do estudo foi investigar como se dá o acesso ao Consultório LGBT por pessoas transexuais e travestis no município de Macaé. Buscou-se a discussão de questões de gênero, uma vez que pessoas LGBTQIA+ têm chegado cada vez mais às clínicas de saúde com demandas específicas, o que causa a necessidade de aperfeiçoamento para atenção a esse público específico. A presente pesquisa foi realizada por meio de abordagem qualitativa. Participaram 13 usuários do Consultório LGBT que se declararam transexuais. Como resultado, foram confirmados vários casos em que as populações estudadas não encontraram a ajuda adequada em outros serviços de saúde. Além disso, o Consultório LGBT se mostrou um espaço de acolhimento e de cuidado em saúde para as pessoas transexuais e travestis da região. Macaé Janeiro LGBTQIA Convivência contemplado predominantemente Buscouse Buscou gênero específicas específico qualitativa 1 resultado disso região

ABSTRACT The LGBT Clinic in Macaé (RJ) operates daily to provide health care for LGBTQIA+ people. This service is part of a network, including the Pedro Ernesto University Hospital and the Casa de Convivência clinic. The service has predominantly served transvestites and transgender people. This study aimed to investigate how trans people access the LGBT Clinic in Macaé. We sought to discuss gender issues, as LGBTQIA+ people have increasingly arrived at health clinics with specific demands, which creates the need for improvement for such a public. This qualitative research was conducted with thirteen users of the LGBT Clinic who self-declared transgender. As a result, several cases were confirmed in which the populations studied did not find adequate help in other health services. Furthermore, the LGBT Clinic was provenly a receptive healthcare space for trans and transvestite people in the region. RJ (RJ LGBTQIA network clinic issues demands public selfdeclared self declared result services Furthermore region

ABSTRACT The LGBT Clinic in Macaé (RJ) operates daily to provide health care for LGBTQIA+ people. This service is part of a network, including the Pedro Ernesto University Hospital and the Casa de Convivência clinic. The service has predominantly served transvestites and transgender people. This study aimed to investigate how trans people access the LGBT Clinic in Macaé. We sought to discuss gender issues, as LGBTQIA+ people have increasingly arrived at health clinics with specific demands, which creates the need for improvement for such a public. This qualitative research was conducted with thirteen users of the LGBT Clinic who self-declared transgender. As a result, several cases were confirmed in which the populations studied did not find adequate help in other health services. Furthermore, the LGBT Clinic was provenly a receptive healthcare space for trans and transvestite people in the region.

RESUMO O Consultório LGBT na cidade de Macaé, estado do Rio de Janeiro, funciona diariamente para o cuidado em saúde de pessoas LGBTQIA+. Esse serviço integra uma rede que conta com o Hospital Universitário Pedro Ernesto e a clínica da Casa de Convivência. O atendimento tem contemplado, predominantemente, as pessoas travestis e transexuais. O objetivo do estudo foi investigar como se dá o acesso ao Consultório LGBT por pessoas transexuais e travestis no município de Macaé. Buscou-se a discussão de questões de gênero, uma vez que pessoas LGBTQIA+ têm chegado cada vez mais às clínicas de saúde com demandas específicas, o que causa a necessidade de aperfeiçoamento para atenção a esse público específico. A presente pesquisa foi realizada por meio de abordagem qualitativa. Participaram 13 usuários do Consultório LGBT que se declararam transexuais. Como resultado, foram confirmados vários casos em que as populações estudadas não encontraram a ajuda adequada em outros serviços de saúde. Além disso, o Consultório LGBT se mostrou um espaço de acolhimento e de cuidado em saúde para as pessoas transexuais e travestis da região.

Resumo O objetivo do presente estudo foi analisar como o atual conceito e as fontes de evidências de validade são utilizados no âmbito da avaliação educacional em larga escala no Brasil. Para tanto, foi realizada uma análise documental, por meio dos relatórios oficiais das maiores avaliações educacionais nacionais aplicadas no país. Os resultados obtidos indicaram que não são apresentadas fontes de evidências de validade suficientes para que se julgue que os testes educacionais analisados sejam válidos para o que se propõem. Ainda é necessário desenvolver o conhecimento técnico dos pesquisadores brasileiros que realizam estudos de validação de testes educacionais, especialmente no âmbito das informações que devem ser levantadas e apresentadas a fim de que se possam utilizar com confiança os resultados obtidos nas provas e nos testes educacionais aplicados no país.

Abstract This study aimed to analyze how the current concept of validity and its sources of evidence have been utilized on large-scale assessment in Brazil. We made a documentary analysis using the official reports of the most important national educational assessments. The results indicated that the reports do not present adequate information about sources of evidence validity, which makes unfeasible to judge the validity of the educational tests analyzed. In this context, it is difficult to say if these tests evaluate what they propose. Therefore, we conclude that, in Brazil, it is still necessary to improve both understanding about what validity is, and what information is necessary to be able to use with confidence the results of different assessments applied in Brazil.

Resumen El objetivo del presente estudio fue analizar cómo el actual concepto y las fuentes de evidencia de validez se utilizan en el marco de la evaluación educativa a gran escala en Brasil. Para ello, se realizó un análisis documental, a través de los informes oficiales de las mayores evaluaciones educativas nacionales aplicadas en el país. Los resultados obtenidos indicaron que no se presentan suficientes fuentes de evidencia de validez para juzgar que las pruebas educativas analizadas son válidas para lo que proponen. Aún es necesario desarrollar el conocimiento técnico de los investigadores brasileños que realizan estudios de validación de pruebas educativas, especialmente en el ámbito de la información que debe ser recolectada y presentada a fin de que se puedan utilizar con confianza los resultados obtenidos en los testes y pruebas educativas se apliquen en el país.

Resumo Em julho de 2020, durante visita em área de pequeno produtor localizada em Laranjal Paulista, São Paulo (Brasil), foram observadas mais de 20 plantas de pitaia-branca [Hylocereus undatus (Haw.) Britton e Rose (syn. Selenicereus undatus (Haw.) D.R. Hunt]apresentando enfezamento e cladódios cloróticos, com porções do caule em declínio. As raízes exibiam numerosas galhas, indicando típica infecção por Meloidogyne sp.. Nematoides foram recuperados de amostras de solo (200 cm³) e 7 g de raiz: 1,7 juvenis (J2) por cm³ de solo, e 954 ovos + J2 de Meloidogyne por grama de raiz foram obtidos. O padrão perineal de 10 fêmeas apontou para . M. incognitaAdicionalmente, o fenótipo de esterase foi obtido por meio de eletroforese de isoenzima. Essa foi realizada com 10 fêmeas adicionais, confirmando a identificação por M. incognita. Ao nosso conhecimento, este é o primeiro relato de M. incognita infestando plantas de pitaia (Hylocereus spp.). e, baseado em nossa observação em campo, M. incognita pode ser um patógeno potencial a esta cultura.

Abstract In July 2020, during a survey carried out in a small farm located in Laranjal Paulista, state of São Paulo (Brazil), more than 20 white pitahaya plants [Hylocereus undatus (Haw.) Britton and Rose (syn. Selenicereus undatus (Haw.) D.R. Hunt] were found with stunting symptoms and showing chlorotic-yellowish stems, some of them already decaying. Roots exhibited numerous galls, indicating Meloidogyne sp. infection. Nematodes were recovered from 200 cm³ and 7 g of roots: 1.7 Meloidogyne juveniles (J2) per cm³ of soil and 954 eggs + J2 per g of roots were found. The perineal pattern of 10 females pointed to M. incognita. Additionally, esterase phenotype was obtained through isozyme electrophoresis, using another 10 females, which identified M. incognita. To our knowledge, this is the first report of M. incognita infesting pitahaya plants (Hylocereus spp.) and, based on our results, M. incognita could be a potential threat to the crop.

Abstract INTRODUCTION: We investigated the prevalence of human T-cell lymphotropic virus types 1 and 2 (HTLV-1/2) infection in patients with hematological diseases from the western Amazon region of Brazil. METHODS: Samples from 306 patients were submitted for the molecular diagnosis of HTLV-1/2 infection by real time PCR (qPCR), with amplification, sequencing, and phylogenetic analysis of the long terminal repeat (LTR) region. RESULTS: A 29-year-old male carrier of sickle cell anemia with a history of multiple blood transfusions was diagnosed with the HTLV-2c subtype. CONCLUSIONS: This study describes the first known occurrence of HTLV-2c in the urban area of Brazil’s western Amazon region.

Abstract INTRODUCTION Mayaro virus (MAYV) was found in Pará state, Brazil, in 1955. Since then, sporadic outbreaks have occurred in different regions of the country. METHODS: Serum sample were collected from 49 individuals in 2016 and were initially tested for dengue virus (DENV) by real-time (RT) polymerase chain reaction (PCR). DENV-negative samples were tested for MAYV and Oropouche virus (OROV) by multiplexed RT quantitative PCR. RESULTS: All samples were negative for DENV and OROV, but MAYV was detected in four samples. CONCLUSIONS: Differential diagnoses of acute febrile syndrome are required, especially in regions where several arboviruses with similar clinical manifestations are endemic.

RESUMO Objetivo: caracterizar impactos do distanciamento social ocasionado pela pandemia da doença do Coronavírus na vida de pessoas com Diabetes Mellitus. Método: estudo descritivo quantitativo, realizado com 102 portadores de Diabetes Mellitus, por meio de formulário virtual, abordando questões sociodemográficas, de autocuidado e de saúde mental, no Brasil no período de maio a junho de 2020. A associação entre as variáveis foi avaliada pelo teste qui-quadrado (p<0,05). Resultados: dos 45 (44,11%) que disseram se alimentar mal, 33 (32,35%) relataram mudanças de peso (p=0,008); com relação à saúde mental, 59 (57,84%) expuseram condições regulares ou ruins; com relação às consultas, 84 indivíduos (82,75%) alegaram interrupção ou irregularidade; dos 58 (56,86%) que declararam prejuízos socioeconômicos, 37 (36,27%) apresentaram dificuldades na adesão de insumos (p<0,000). Conclusão: medidas multiprofissionais devem ser focadas nos fatores que influenciam negativamente o controle metabólico, assim como em estabelecer atendimento a distância, para minimizar a diminuição da atenção assistencial.

ABSTRACT Objective: to characterize the impacts of social distancing caused by the Coronavirus disease pandemic on the lives of people with Diabetes Mellitus. Method: a descriptive study with a quantitative approach, carried out in Brazil from May to June 2020 with 102 patients with Diabetes Mellitus, through a virtual form, addressing sociodemographic, self-care and mental health issues. The association between the variables was assessed using the chi-square test (p<0.05). Results: of the 45 (44.11%) individuals who stated eating poorly, 33 (32.35%) reported weight changes (p=0.008); in relation to mental health, 59 (57.84%) presented regular or bad conditions; with regard to consultations, 84 individuals (82.75%) indicated interruption or irregularity; of the 58 (56.86%) who stated socioeconomic losses, 37 (36.27%) had difficulties in adherence to inputs (p<0.000). Conclusion: multi-professional measures must be focused on the factors that exert a negative influence on metabolic control, as well as on establishing remote care, to minimize the reduction in assistance.

RESUMEN Objetivo: caracterizar los impactos del distanciamiento social provocado por la pandemia de la enfermedad por Coronavirus en la vida de las personas con Diabetes Mellitus. Método: estudio descriptivo cuantitativo, realizado con 102 pacientes con Diabetes Mellitus, a través de un formulario virtual, con el abordaje de temas sociodemográficos, de autocuidado y de salud mental, en Brasil de mayo a junio de 2020. La asociación entre variables fue evaluada por la prueba de chi-cuadrado (p<0,05). Resultados: de los 45 (44,11%) que admitieron comer mal, 33 (32,35%) reportaron cambios de peso (p=0,008); con respecto a la salud mental, 59 (57,84%) expusieron condiciones regulares o malas; En cuanto a las consultas, 84 personas (82,75%) alegaron interrupción o irregularidad; de los 58 (56,86%) que declararon pérdidas socioeconómicas, 37 (36,27%) tuvieron dificultades en la adhesión de insumos (p<0,000). Conclusión: las medidas multiprofesionales deben centrarse en los factores que influyen negativamente en el control metabólico, así como en el establecimiento de cuidados a distancia, para minimizar la disminución de la atención asistencial.

RESUMO Tivemos como objetivo investigar a influência do polimorfismo do gene ACTN3 na responsividade à potencialização do desempenho de salto com contra movimento (CMJ) pós-ativação (PAPE). Dezesseis homens destreinados foram divididos em dois grupos: homozigotos para os alelos X (XX, n = 9) ou R (RR, n = 7). A altura de CMJ, a potência média e a força vertical aplicada durante o salto pelos participantes foram determinadas duas vezes (CMJ1 e CMJ2) em duas condições: controle (CON) e potencializado (PAPE). Na condição CON, os CMJ foram realizados antes e depois de um período de 15 minutos de repouso. Na condição PAPE, os CMJ foram realizados 15 minutos antes e 4 minutos após a realização de cinco agachamentos com carga de cinco repetições máximas (5RM). As diferentes condições foram realizadas em dias separados e em ordem randomizada. ANOVAs fatoriais de três caminhos foram utilizadas para comparar diferenças entre condições, tempos e grupos. O tamanho do efeito foi calculado pelo d de Cohen. Os tamanhos do efeito para alterações na altura de CMJ para os grupos CON e PAPE foram 0.04 e 0.08, respectivamente. Não houve diferenças significantes entre os grupos XX e RR na altura de salto em condição basal (1.07 ± 2.54 cm e -0.82 ± 2.56 cm, respectivamente). Não houve diferenças significativas na responsividade à PAPE entre os grupos (XX = -0.20 ± 1.6 cm e RR = -0.81 ± 2.7 cm). O polimorfismo do gene ACTN3 parece não ser influenciar isoladamente a responsividade à PAPE.

ABSTRACT We aimed to investigate the influence of alpha-actinin-3 (ACTN3) R577X polymorphism on responsiveness to post-activation performance enhancement (PAPE) of countermovement jumps (CMJ) in untrained subjects. Sixteen untrained men were allocated into two groups according to their ACTN3 gene alleles: homozygous for the X allele (XX, n = 9) or homozygous for the R allele (RR, n = 7). CMJ height, mean power output and vertical force were determined twice (CMJ1 and CMJ2) in two conditions: control (CON) and potentiated (PAPE). In the CON condition, CMJ were performed before and after a 15-min rest. In the PAPE condition, CMJ were performed 15 min before and 4 min following five squats with a 5-repetition maximum (5RM) load. Different conditions were applied on separate days in a randomized order. Statistical analysis involved three-way ANOVAs to compare the differences between conditions (CON and PAPE), time (CMJ1 and CMJ2), and groups (XX and RR). Significance level considered was p < 0.05. Effect sizes were calculated as Cohen’s d. The effect sizes for changes in CMJ height for CON and following pre-activation for PAPE were 0.04 and 0.08, respectively. No significant differences were found for CMJ height between XX and RR at baseline (1.07 ± 2.54 cm e -0.82 ± 2.56 cm, respectively). No differences were found (p>0.05) in responsiveness to PAPE between the groups (XX = -0.20 ± 1.6 cm and RR = -0.81 ± 2.7 cm). We conclude that ACTN3 gene polymorphisms does not influence responsiveness to PAPE.

ABSTRACT Plant parasitic nematodes are major threats to Brazilian and world agriculture. Among them, Pratylenchus brachyurus and Meloidogyne incognita stand out as major pests for several crops, including corn, cotton, soybean among others, which can be components of integrated crop-livestock-forestry systems (ICLFs). In this context, information about the host status of eucalypts (Corymbia spp. and Eucalyptus spp.) to plant parasitic nematodes becomes more relevant in Brazil, due to the use of eucalypts in ICLFs. If tree components used on this system increase the population density of P. brachyurus and M. incognita, it is possible that these pathogens could damage shorter-cycle crops. Since information about the host status of eucalypts to plant parasitic nematodes is scarce, this study evaluated the host status of some eucalypt species to P. brachyurus and M. incognita. Two greenhouse trials were done to evaluate the reproduction of P. brachyurus and one to M. incognita, using some of the most cultivated species and hybrids of eucalypts in Brazil. The population growth of P. brachyurus increased on Corymbia citriodora, Eucalyptus grandis, Eucalyptus dunnii × Eucalyptus urophylla, and E. grandis × E. urophylla after ~90 days of inoculation. Conversely, despite M. incognita reproducing well in the control plants, no individuals were recovered from C. citriodora, E. urophylla and E. grandis × E. urophylla, which were classified as resistant plants. Based on both obtained and available data, M. incognita poses no threat to eucalypt species today. However, P. brachyurus is suggested to be a threat to eucalypts.

Oropouche virus (OROV) is an arthropod-borne virus of the Peribunyaviridae family, transmitted to humans primarily by Culicoides paraensis. It is one of the main arboviruses infecting humans in Brazil, primarily in the Amazon Region. Here, we report the detection of OROV in the saliva and urine of a patient whose samples were collected five days after the onset of symptoms. Nucleotide sequencing and phylogenetic analysis further confirmed the results. To our knowledge, this is the first study reporting the detection of OROV in the saliva and urine of an infected patient. In addition, the results of our study expand the current knowledge pertaining to the natural history of Oropouche fever.

Abstract Duplex and super duplex stainless steels have high corrosion resistance, excellent mechanical properties, and high impact strength. Such characteristics make these steels able to operate in various segments of the industry, especially in aggressive environments. These alloys have higher strength than austenitic and ferritic stainless steels and their operation is generally restricted to temperatures lower than 300 °C. Most steels and alloys only exhibit elasto-viscoplastic behavior at temperatures higher than 1/3 of the absolute melting temperature. The objective of this work was to make an experimental study showing that the duplex and superduplex steels present a rate-dependent behavior even at room temperature (around 25 °C). Two different alloys: duplex stainless steel UNS 31803F51 and super duplex UNS S32760GRF55 were used in the study. Simple models were proposed to describe how the rate-dependent portion of the stress (called at this paper “the viscous term”) depends on the strain rate. A simple procedure to identify experimentally all material constants that appear in the theory is presented. The experimental results are in very good agreement with the model predictions.

Measles is a human infectious disease of global concern that is caused by the measles virus. In this study, we report the complete genome sequencing of one measles virus isolate, genotype D8, that was obtained directly from a urine sample in Boa Vista city, the capital of Roraima state in Brazil. Phylogenetic reconstruction grouped the genome described in this study with that of samples from Australia, South Korea, and Italy. To our knowledge, this is the first complete genome sequence of a wild-type measles virus reported from Latin America. Therefore, the present data strengthen the current knowledge on the molecular epidemiology of measles worldwide.