Abstract The Cachoeirinha Sn ± (Nb-Ta) deposit is an important producer of the Rondônia Tin Province. It is inserted in the regional unit named Rondônia Intrusive Suite (995–956 Ma) and hosts granular accumulations of columbite group minerals (CGM) embedded in thick Cenozoic colluvial-alluvial covers. Cachoeirinha CGM have subrounded to angular grains, with irregular to regular internal zoning, micro-inclusion, and exsolution features. They have columbite-(Fe) as the dominant mineral phase, with variation in the Ta/(Ta+Nb) ratio and with Sn, Ti, W, U, Ba, Cr, REE, and V as chemical impurities. It has high total REE content (LREEN depleted, HREEN enriched, Ce and Eu anomalies), δ18O = 2.78‰, and with two U-Pb age groups: 1052 ± 6 and 909 ± 7 Ma. This information indicates that physicochemical oscillations favored the ionic substitutions and resorption mechanisms between Nb ↔ Ta, as well as coupled substitutions with the entry of geochemical impurities, according to the equation: 3(Sn, Ti, U, Si)4+ + (W, Cr)6+ ↔ 2(V, Nb, Ta)5+ + 2(Al, REE)3+ + (Fe, Mn, Ba)2+, at the temperature range between 400° and 500°C. Finally, the Cachoeirinha Sn ± (Nb-Ta) alluvial deposit host ore is related to at least two Neo-Mesoproterozoic magmatic pulses. NbTa Ta (Nb-Ta Province 995–956 995956 995 956 (995–95 Ma (CGM colluvialalluvial colluvial covers grains zoning microinclusion, microinclusion micro inclusion, inclusion micro-inclusion features columbiteFe Fe columbite-(Fe phase Ta/Ta+Nb TaTaNb Ta/ Ta+Nb Ta/(Ta+Nb Ti W U Ba Cr impurities LREEN depleted enriched anomalies, anomalies , anomalies) δO δ O 278 2 78 2.78‰ UPb Pb groups 105 90 equation 3Sn, 3Sn 3 3(Sn Si4+ Si4 Si 4+ 4 Si)4 (W Cr6+ Cr6 6+ Cr)6 2V, 2V V, 2(V Ta5+ Ta5 5+ 5 Ta)5 2Al, 2Al Al Al, 2(Al REE3+ REE3 3+ REE)3 Fe, (Fe Mn Ba2+, Ba2 2+, Ba)2+ 400 500C C 500 500°C Finally NeoMesoproterozoic Neo Mesoproterozoic pulses 995–95 99595 99 95 (995–9 TaNb 27 2.78 10 9 Si) Cr) Ta) REE) Ba2+ 2+ Ba)2 40 50 995–9 9959 (995– 2.7 1 Ba) 995– (995 2. (99 (9 (