The short story The Alienist was written by Machado de Assis and published between 1881 and 1882. The story has as its protagonist Simão Bacamarte, an alienist, who may be the precursor of the psychiatrist. Bacamarte occupies a prominent place in the village of Itaguaí, in Rio de Janeiro, after returning from his studies in Europe. He installed the Casa de Orates or Casa Verde, an asylum to treat the mental health of those considered alienated. With the support of councilors and the local population, he was successful, but he became obsessed and ended up interning almost all of the residents. The bibliographic review methodology was used, which aims to survey materials related to the study topic. Thus, this article aims to analyze Machado's work in its critique of sanity and madness, reflecting on the role and authority of the psychiatrist, in addition to thinking about the model of hospitalization in asylums and hospices.

El cuento El alienista fue escrito por Machado de Assis y publicado entre 1881 y 1882. La historia tiene como protagonista a Simão Bacamarte, un alienista, quien puede ser el precursor del psiquiatra. Bacamarte ocupa un lugar destacado en la aldea de Itaguaí, en Río de Janeiro, luego de regresar de sus estudios en Europa. Instaló la casa Orates o Casa Verde, un asilo para tratar la salud mental de aquellos considerados alienados. Con el apoyo de los concejales y de la población local, tuvo éxito, pero se obsesionó y acabó internando a casi todos los vecinos. Se utilizó la metodología de revisión bibliográfica, que tiene como objetivo relevar materiales relacionados con el tema de estudio. Así, este artículo tiene como objetivo analizar la obra de Machado en su crítica a la cordura y la locura, reflexionando sobre el papel y la autoridad del psiquiatra, además de pensar sobre el modelo de hospitalización en asilos y hospicios.

O conto O Alienista foi escrito por Machado de Assis e publicado entre 1881 e 1882. A história tem como protagonista Simão Bacamarte, alienista, que pode ser o precursor do psiquiatra. Bacamarte ocupa lugar de destaque na vila de Itaguaí, no Rio de Janeiro, após voltar de seus estudos na Europa. Instalou a casa de Orates ou Casa Verde, um asilo para tratar da saúde mental dos considerados alienados. Com o apoio dos vereadores e da população local, logrou êxito, mas se tornou obcecado e acabou internando quase todos os moradores. Utilizou-se a metodologia de revisão bibliográfica que tem por objetivo o levantamento de materiais relacionados ao tema do estudo. Assim, este artigo tem por objetivo analisar a obra machadiana em sua crítica sobre a sanidade e a loucura, refletindo sobre o papel e autoridade do médico psiquiatra, além de pensar o modelo de internação em asilos e hospícios.

ABSTRACT Objective: To systematically review the literature in search of the most suitable and effective nutritional interventions and indications for the nutritional treatment of children and adolescents with cerebral palsy (CP). Data source: This review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The articles were selected from seven databases (Cochrane, Literatura Latino-Americana e do Caribe em Ciências da Saúde — Lilacs, Embase, United States National Library of Medicine — PubMed, Scientific Electronic Library Online — SciELO, Scopus, and Web of Science). Studies from a pediatric group (0 to 18 years old) diagnosed with CP were included and the search strategy included the descriptors: “children” OR “childhood” AND “nutritional therapy” OR “nutritional intervention” OR “nutrition” OR “nutritional support” OR “diet” AND “cerebral palsy” OR “cerebral injury”. Methodological quality was assessed using the checklist for cross-sectional analytical studies, the Newcastle-Ottawa scale or the Cochrane Collaboration tool for clinical trials. Data synthesis: Fifteen studies (n=658) published from 1990 to 2020 met the inclusion criteria. All of them had a low risk of bias. The data showed that children and adolescents with CP have worse nutritional status than those normally developed. Those who received hypercaloric and hyperprotein nutritional supplementation benefited from its use. Studies indicate that enteral nutrition should be considered when nutritional needs are not met by the oral diet, especially in cases where oral motor functions are impaired. In addition, there was a direct relationship between the consistency of food, the level of motor function and nutritional status. Conclusions: Children and adolescents with CP have a greater risk of malnutrition. The use of nutritional supplementation may help with weight gain. In addition, enteral nutrition and modification of food texture have been used to improve the nutritional status of this group. Objective CP. . (CP) source MetaAnalyses Meta Analyses PRISMA (PRISMA guidelines Cochrane, (Cochrane LatinoAmericana Latino Americana Lilacs Embase PubMed SciELO Scopus Science. Science Science) 0 ( 1 old descriptors “children childhood “childhood therapy intervention “nutrition support diet “diet injury. injury injury” crosssectional cross sectional NewcastleOttawa Newcastle Ottawa trials synthesis n=658 n658 n 658 (n=658 199 202 criteria bias developed impaired addition Conclusions malnutrition gain (CP n=65 n65 65 (n=65 19 20 n=6 n6 6 (n=6 2 n= (n= (n

RESUMO Objetivo: Revisar sistematicamente a literatura em busca das intervenções e indicações nutricionais mais adequadas e eficazes para o tratamento nutricional de crianças e adolescentes com paralisia cerebral (PC). Fontes de dados: Esta revisão foi conduzida de acordo com as diretrizes Preferred Reporting Items for Systematic Reviews and Meta-Analyses — PRISMA. Os artigos foram selecionados em sete bases de dados (Cochrane, Literatura Latino-Americana e do Caribe em Ciências da Saúde — Lilacs, Embase, United States National Library of Medicine — PubMed, Scientific Electronic Library Online — SciELO, Scopus, and Web of Science). Foram incluídos estudos de um grupo pediátrico (zero a 18 anos) com diagnóstico de PC e a estratégia de busca incluiu os descritores: “children” OR “childhood” AND “nutritional therapy” OR “nutritional intervention” OR “nutrition” OR “nutritional support” OR “diet” AND “cerebral palsy” OR “cerebral injury”. A qualidade metodológica foi avaliada utilizando a lista de verificação para estudos transversais analíticos, escala Newcastle-Ottawa ou ferramenta da Cochrane Collaboration, para ensaios clínicos. Síntese dos dados: Quinze estudos (n=658) publicados de 1990 a 2020 preencheram os critérios de inclusão. Todos tiveram baixo risco de viés. Os dados mostraram que crianças e adolescentes com PC apresentam pior estado nutricional do que os normalmente desenvolvidos. Aqueles que receberam suplementação nutricional hipercalórica e hiperproteica beneficiaram-se de seu uso. Estudos demonstram que a nutrição enteral deve ser considerada quando as necessidades nutricionais não são supridas pela dieta oral, principalmente nos casos em que as funções oromotoras estão prejudicadas. Além disso, houve relação direta entre a consistência dos alimentos, o nível de função motora e o estado nutricional. Conclusões: Crianças e adolescentes com PC têm maior risco de desnutrição. O uso de suplementação nutricional pode auxiliar no ganho de peso desses pacientes. Além disso, a nutrição enteral e a modificação da textura dos alimentos têm sido artifícios utilizados para a melhora do estado nutricional neste grupo. Objetivo PC. . (PC) MetaAnalyses Meta Analyses PRISMA Cochrane, (Cochrane LatinoAmericana Latino Americana Lilacs Embase PubMed SciELO Scopus Science. Science Science) zero 1 anos descritores children “children childhood “childhood nutritional therapy intervention nutrition “nutrition support diet “diet palsy injury. injury injury” analíticos NewcastleOttawa Newcastle Ottawa Collaboration clínicos n=658 n658 n 658 (n=658 199 202 inclusão viés desenvolvidos beneficiaramse beneficiaram se oral prejudicadas disso Conclusões desnutrição pacientes (PC n=65 n65 65 (n=65 19 20 n=6 n6 6 (n=6 2 n= (n= (n

ABSTRACT The purpose of this paper is to prioritize which waste should be treated by Lean Healthcare in a medical clinic of a middle-sized Brazilian hospital, using the multicriteria decision support method THOR 2. It focusses on structuring the problem, establishing alternatives through the study hospital and Lean interventions already made in it, and determining the criteria and parameters of THOR 2 with the help of Value Focus Thinking (VFT) and the hospital directors. THOR 2 was able to identify, taking into account its preference relationships in S2, that establishing a Kanban within the hospital’s medical clinic is the preferred and the main contribution and novelty to the literature is the way that multicriteria methods can help in Lean Healthcare decision making. As conclusions, it was possible to establish a prioritization order, maintaining the concept of continuous improvement, arising from Lean Healthcare, while respecting the limits and restrictions of the hospital. middlesized middle sized problem VFT (VFT directors identify S2 S hospitals s making conclusions order improvement

ABSTRACT BACKGROUND: Colorectal cancer is the third most common type of cancer in Brazil, despite the availability of screening methods that reduce its risk. Colonoscopy is the only screening method that also allows therapeutic procedures. The proper screening through colonoscopy is linked to the quality of the exam, which can be evaluated according to quality criteria recommended by various institutions. Among the factors, the most used is the Adenoma Detection Rate, which should be at least 25% for general population. AIMS: To evaluate the quality of the screening colonoscopies performed in a quarternary private Brazilian hospital. METHODS: This is a retrospective study evaluating the quality indicators of colonoscopies performed at a private center since its inauguration. Only asymptomatic patients aged over 45 years who underwent screening colonoscopy were included. The primary outcome was the Adenoma Detection Rate, and secondary outcomes included polyps detection rate and safety profile. Subanalyses evaluated the correlation of endoscopic findings with gender and age and the evolution of detection rates over the years. RESULTS: A total of 2,144 patients were include with a mean age of 60.54 years-old. Polyps were diagnosed in 68.6% of the procedures. Adenoma detection rate was 46.8%, with an increasing rate over the years, mainly in males. A low rate of adverse events was reported in 0.23% of the cases, with no need for surgical intervention and no deaths. CONCLUSIONS: This study shows that high quality screening colonoscopy is possible when performed by experienced endoscopists and trained nurses, under an adequate infrastructure. BACKGROUND Brazil risk procedures exam institutions factors Rate 25 population AIMS hospital METHODS inauguration 4 profile RESULTS 2144 2 144 2,14 6054 60 54 60.5 yearsold. yearsold old. old years-old 686 68 6 68.6 468 46 8 46.8% males 023 0 23 0.23 cases deaths CONCLUSIONS nurses infrastructure 214 14 2,1 605 5 60. 68. 46.8 02 0.2 21 1 2, 46. 0.

RESUMO RACIONAL: O câncer colorretal é o terceiro tipo de câncer mais comum no Brasil apesar dos métodos de rastreamento que reduzem seu risco. A colonoscopia é o único método com possibilidade terapêutica. O adequado rastreio por colonoscopia está relacionado à qualidade dos exames, avaliados de acordo com critérios de qualidade recomendados por diversas instituições. Dentre os fatores, o mais utilizado é a Taxa de Detecção de Adenoma, que deve ser de pelo menos 25% na população geral. OBJETIVOS: Avaliar a qualidade das colonoscopias de rastreamento do câncer colorretal realizadas em um centro brasileiro. MÉTODOS: Estudo retrospectivo avaliando os indicadores de qualidade em colonoscopias de rastreio nos pacientes assintomáticos com mais de 45 anos. O desfecho primário foi a Taxa de Detecção de Adenoma, e os secundários incluíram a taxa de detecção de pólipos e a segurança do procedimento. Subanálises incluíram a correlação dos achados endoscópicos com sexo e idade e a evolução das taxas de detecção de adenoma ao longo dos anos. RESULTADOS: Foram incluídos 2.144 pacientes, com media de idade de 60.54 anos. Pólipos foram diagnosticados em 68,6% dos procedimentos. A taxa de detecção de adenoma foi de 46,8%, aumentando ao longo dos anos, principalmente em homens. A taxa de efeitos adversos foi de 0.23%, sem necessidade de intervenção cirúrgica ou registro de óbitos. CONCLUSÕES: Este estudo demonstra que é possível realizar colonoscopias com qualidade para o rastreio do câncer colorretal quando efetuadas por médicos experientes e enfermeiras treinadas em hospitais com infraestrutura adequada. RACIONAL risco terapêutica exames instituições fatores Adenoma 25 geral OBJETIVOS brasileiro MÉTODOS 4 anos procedimento RESULTADOS 2144 2 144 2.14 6054 60 54 60.5 686 68 6 68,6 procedimentos 468 46 8 46,8% homens 023 0 23 0.23% óbitos CONCLUSÕES adequada 214 14 2.1 605 5 60. 68, 46,8 02 0.23 21 1 2. 46, 0.2 0.

ABSTRACT The selection process for instructors at the Brazilian Air Force Officers Improvement School (EAOAR) needs improvement to provide clearer guidance to the Commandant. This article aims to streamline and enhance the process by making it more efficient, less subjective, and more reliable. Researchers employed the Analytic Hierarchy Process (AHP) to determine criteria weights and the Technique for Order Preference by Similarity to Ideal Solution (TOPSIS) to rank candidates. They used Three Decision Methods (3DM) Software Web (v.1) for efficient calculations. Results showed that candidates closer to the Positive Ideal Solution (PIS) received favorable indications, while those closer to the Negative Ideal Solution (NIS) faced rejections. The AHP-TOPSIS hybrid approach successfully ranked candidates and expedited the process. Moreover, this approach has broader applications, including assessing candidates for international missions in the Brazilian Navy and Army, and evaluating employee performance in any organization. Future research could explore classification methods like the ELECTRE-TRI. EAOAR (EAOAR Commandant subjective reliable AHP (AHP TOPSIS (TOPSIS 3DM DM (3DM v.1 v1 v 1 (v.1 calculations PIS (PIS indications NIS (NIS rejections AHPTOPSIS Moreover applications Army organization ELECTRETRI. ELECTRETRI ELECTRE TRI. TRI ELECTRE-TRI v. (v. (v

Abstract This study evaluated the effects of broiler age (A) and levels of replacement (L) of control diet (CD) on the utilization of energy and nutrients of whole corn germ. 720 one-day-old broilers (b) were allocated at completely randomized design to six treatments and six replicates, in three assays: pre-starter (1-8 days, 10 b/cage), starter (15-22 days, 6 b/cage), and grower (28-35 days, 4 b/cage) phases. The treatments were: CD and four test diets (L): 100, 150, 200, 250, or 300 g kg-1 of the CD replaced by WCG levels. The data were adjusted to the response surface model. The stationary points for apparent energy metabolizable (AME) and AME corrected for nitrogen balance (AMEn) were: 4173 and 3591 kcal kg-1, respectively, and coefficients of gross energy (AMCGE), crude protein (AMCCP), dry matter (AMCDM), and ether extract (AMCEE) were: 49.3, 40.4, 72.6, and 61.3%, respectively; and Ileal digestibility coefficient of crude protein (IDCCP), dry matter (IDCDM), digestibility crude protein values (DCP), and digestibility dry matter value (DDM) were: 78.0, 57.96, 8.50, and 56.17%, respectively. The EP for AMEn was at 18 days of age, 28 g kg-1 WCG. There was a correlation between A and L on digestibility and metabolisability of nutrient’s WCG. (A (L (CD germ 72 onedayold one day old b (b replicates assays prestarter pre 1 8 (1- b/cage, bcage b/cage , cage 1522 15 22 (15-2 2835 35 (28-3 phases 100 150 200 250 30 kg1 kg kg- model (AME (AMEn 417 359 kg1, 1, respectively AMCGE, AMCGE (AMCGE) AMCCP, AMCCP (AMCCP) AMCDM, AMCDM (AMCDM) AMCEE (AMCEE 493 49 3 49.3 404 40 40.4 726 72.6 613 61 61.3% IDCCP, IDCCP (IDCCP) IDCDM, IDCDM (IDCDM) DCP, DCP (DCP) DDM (DDM 780 78 0 78.0 5796 57 96 57.96 850 50 8.50 5617 56 17 56.17% 2 nutrient s 7 (1 152 (15- 283 (28- 20 25 41 (AMCGE (AMCCP (AMCDM 49. 40. 72. 61.3 (IDCCP (IDCDM (DCP 78. 579 5 9 57.9 85 8.5 561 56.17 ( (15 (28 61. 57. 8. 56.1 (2 56.

ABSTRACT Post-acute COVID-19 syndrome, or long COVID, presents with persistent symptoms, including cough, dyspnea, and fatigue, extending beyond one month after SARS-CoV-2 infection. Cardiac complications such as chest pain and arrhythmias have raised concerns, with chronotropic incompetence (CI), an inadequate heart rate increase during exercise, emerging as a significant condition contributing to diminished exercise tolerance and quality of life. This study estimated the prevalence of CI and explored its association with aerobic capacity and physical activity levels in long COVID patients. A cross-sectional study was conducted at a private hospital in Sergipe, Brazil, involving 93 patients over 18 years old with persistent post-COVID-19 symptoms after confirmed SARS-CoV-2 infections. Exclusion criteria included beta-blocker use, inadequate respiratory exchange ratio, and inability to complete cardiopulmonary exercise testing (CPET). Clinical histories, CPET results, and chronotropic index calculation were used to identify CI, with logistic regression analyzing associated factors. Of the participants (mean age 45 years; average duration since COVID-19 diagnosis 120 days), 20.4% were diagnosed with CI. Logistic regression identified a strong association between CI and sedentary behavior (OR 11.80; 95% CI 2.54 to 54.78; p=0.001). Patients with CI showed lower predicted peak heart rates and maximal oxygen uptake. The prevalence of CI among long COVID patients in this study was approximately 20%, associated with decreased aerobic capacity and increased sedentary behavior. These findings highlight the need for timely diagnosis and therapeutic interventions, including cardiopulmonary rehabilitation, to enhance the quality of life in post-COVID patients with CI. The study’s cross-sectional design and its specific context have limited causality inference and generalizability, underscoring the importance of further research in diverse settings. Postacute Post acute COVID19 19 COVID-1 syndrome cough dyspnea fatigue SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- infection concerns , (CI) crosssectional cross sectional Sergipe Brazil 9 1 postCOVID19 postCOVID post post-COVID-1 infections betablocker beta blocker use ratio CPET. . (CPET) histories results factors mean 4 12 days, days days) 204 20 20.4 OR 11.80 1180 11 80 95 254 54 2.5 54.78 5478 78 p=0.001. p0001 p p=0.001 0 001 p=0.001) uptake 20% interventions rehabilitation studys s generalizability settings COVID1 COVID- SARS-CoV (CI postCOVID1 post-COVID- (CPET 20. 11.8 118 8 25 5 2. 54.7 547 7 p000 p=0.00 00 11. 54. p00 p=0.0 p0 p=0. p=0 p=

ABSTRACT Objective: describe the process of translation and cross-cultural adaptation of the Mayo High Performance Team Scale into Brazilian Portuguese. Method: descriptive study of validation and cross-cultural adaptation of the scale, carried out virtually, following assumptions proposed by Beaton and collaborators. It had a sample of 40 experts, and carried out two rounds, one for validation and one for final assessment. Results: after following all translation steps, the scale was presented to the committee of experts who reached a consensus (IVC between 0.9 and 1.0) that there was no discrepancy, after evaluating the semantic, idiomatic, experiential and conceptual equivalences between the original scale and the translated version. Conclusion: The Brazilian Portuguese version of the MHPTS was adequately translated and validated, revealing excellent potential for use in clinical simulation contexts for multidisciplinary scenarios. Objective crosscultural cross cultural Method virtually collaborators 4 rounds assessment Results steps IVC 09 0 9 0. 1.0 10 1 discrepancy semantic idiomatic Conclusion validated scenarios 1.

RESUMO Objetivo: descrever o processo de tradução e adaptação transcultural da escala Mayo High Performance Team Scale para o português brasileiro. Método: estudo descritivo de validação e adaptação transcultural da escala, realizado de maneira virtual, seguindo pressupostos propostos por Beaton e colaboradores. Contou com uma amostra de 40 especialistas, e realizou duas rodadas, sendo uma de validação e uma de apreciação final. Resultados: após seguir todas as etapas de tradução a escala foi apresentada ao comitê de especialistas que chegou a um consenso (IVC entre 0,9 e 1,0) sobre não haver qualquer discrepância, após avaliação das equivalências semântica, idiomática, experiencial e conceitual entre a escala original e a versão traduzida. Conclusão: A versão em português brasileiro da MHPTS foi adequadamente traduzida e validada, revelando excelente potencial de utilização em contextos de simulação clínica para cenários multiprofissionais. Objetivo Método virtual colaboradores 4 rodadas final Resultados IVC 09 0 9 0, 1,0 10 1 discrepância semântica idiomática Conclusão validada multiprofissionais 1,

RESUMO Introdução: a sedação e analgesia são procedimentos fundamentais para crianças submetidas a intervenções invasivas, devendo-se evitar complicações durante sua realização. A simulação in situ permite, por sua vez, capacitações nos ambientes reais de prática para aprimorar as competências técnicas e não técnicas dos profissionais para tais procedimentos. Embora seja uma ferramenta de grande utilidade, muitas vezes não é aproveitada pelo despreparo para seu planejamento e aplicação. Objetivo: elaborar e validar um cenário de simulação in situ no atendimento de urgências pediátricas com uso de sedação para realização de procedimento invasivo. Método: estudo descritivo de construção e validação de conteúdo de um cenário de simulação in situ, por meio do método Delphi, seguindo os seguintes passos: 1) definição do problema e seleção de especialistas; 2) desenvolvimento do documento inicial; 3) rodadas para validação com análise das respostas e feedback (até obtenção do consenso pelo Índice de Validação de Conteúdo); 4) relatório final. Resultados: Os especialistas indicaram sugestões devidamente aproveitadas e o cenário obteve, em todos os itens, um IVC maior que 80,0% demonstrando sua alta validade e confiabilidade. Ao usar especialistas para validar o cenário, seus insights garatem maior precisão e confiabilidade à engenharia de construção dos cenários. Conclusão: espera-se, que este estudo permita a replicação do cenário em diferentes contextos de formação facilitando e incentivando a capacitação profissional a partir de um modelo de cenário baseado em melhores evidências e práticas. Introdução invasivas devendose devendo se permite vez utilidade aplicação Objetivo invasivo Método Delphi passos 1 2 inicial 3 até Conteúdo Conteúdo) 4 final Resultados obteve itens 800 80 0 80,0 cenários Conclusão esperase, esperase espera se, espera-se práticas 8 80,

ABSTRACT Introduction: sedation and analgesia are fundamental procedures for children undergoing invasive interventions, and complications must be avoided during their implementation. In situ simulation allows, in turn, training in real practice environments to improve the technical and non-technical skills of professionals for such procedures. Although it is a very useful tool, it is often not used due to lack of preparation for its planning and application. Objective: develop and validate an in situ simulation scenario in pediatric emergency care using sedation to perform an invasive procedure. Method: descriptive study of construction and content validation of an in situ simulation scenario, using the Delphi method, following the following steps: 1) definition of the problem and selection of experts; 2) development of the initial document; 3) rounds for validation with analysis of responses and feedback (until consensus is reached by the Content Validation Index); 4) final report. Results: The experts indicated suggestions that were duly used and the scenario obtained, in all items, a CVI greater than 80.0%, demonstrating its high validity and reliability. By using experts to validate the scenario, their insights guarantee greater precision and reliability in scenario construction engineering. Conclusion: It is expected that this study will allow the replication of the scenario in different training contexts, facilitating and encouraging professional training based on a scenario model based on best evidence and practices. Introduction interventions implementation allows turn nontechnical non tool application Objective procedure Method method steps 1 2 document 3 until Index Index) 4 report Results obtained items 800 80 0 80.0% engineering Conclusion contexts practices 8 80.0 80.

Chagas disease is a tropical neglected disease that affects millions of people worldwide, still demanding a more effective and safer therapy, especially in its chronic phase which lacks a treatment that promotes substantial parasitological cure. The technical note of Romanha and collaborators published in 2010 aimed establish a guideline with the set of minimum criteria and decision gates for the development of new agents against Trypanosoma cruzi with the focus on developing new antichagasic drugs. In this sense, the present review aims to update this technical note, bringing the state of the art and new advances on this topic in recent years. worldwide therapy cure 201 drugs sense years 20 2

ABSTRACT This study analyzes the operational efficiency of Brazil’s 30 largest airports from 2014 to 2018, using a two-stage model. Operational efficiency is defined as an airport’s capacity to effectively utilize resources, such as facilities, staff, and technology, to cater to air traffic and passenger needs. The first stage involved measuring operational efficiency through data envelopment analysis. The second stage used a three-level hierarchical linear model to identify influencing variables. Key findings reveal that location significantly impacts airport efficiency, which generally declined during the study period. The interest rate, the only notable economic factor, had a negative effect on efficiency. Factors like the number of aircraft parking positions, years of airport operation, and the number of airlines positively influenced efficiency. Conversely, governance structure, airport size, commercial establishment count, and vehicle parking lot numbers didn’t notably affect efficiency variation. This methodological approach provided more accurate predictions than traditional regression models. Brazils Brazil s 3 201 2018 twostage two resources facilities staff technology needs analysis threelevel three level variables period rate factor positions operation Conversely structure size count didnt didn t variation models 20 2

Resumo Descobertas recentes de deposições funerárias no sítio Uruguai 1 contribuem com novos elementos sobre o comportamento mortuário relativos à unidade arqueológica Guarani. Tratam-se de cinco sepultamentos que incluem uma deposição em urna e ao menos quatro diretamente no solo, sendo a primeira vez que se documenta este último tipo de deposição para o alto vale do rio Uruguai. A ocupação Guarani desse sítio se situa da primeira metade do século XV até o século XVIII (510 ± 20 e 240 ± 30 anos 14C AP). Esse sítio está inserido no contexto da área arqueológica da Foz do Chapecó, que vem sendo estudada nas últimas duas décadas e na qual já foram documentadas pelo menos outras sete deposições funerárias, todas em urna. Neste artigo, apresentamos os achados de campo e laboratório sobre as deposições do sítio Uruguai 1, assim como novas datações radiocarbônicas para o nível analisado. Os dados não apenas contribuem para a arqueologia regional, mas trazem novos elementos para o entendimento do comportamento mortuário dessa unidade arqueológica na bacia do Prata. Tratamse Tratam solo 510 (51 2 24 3 C AP. AP . AP) Chapecó artigo analisado regional Prata 51 (5 5 (

Abstract Recent discoveries of funerary depositions at the Uruguay 1 site provide new elements on the mortuary behavior related to the Guarani archaeological unit. Five burials including one urn deposition and at least four directly in the ground were discovered. This last behavior had not yet been documented for the upper Uruguay river. The Guarani occupation of this site dates from the first half of the 15th century to the 18th century (510 ± 20 and 240 ± 30 years 14C AP). This site is inserted in the context of the archaeological area of Foz do Chapecó, which has been studied in the last two decades and in which at least seven other burials in urns have already been documented. In this article we present new field and laboratory findings on depositions from the Uruguai 1 site, as well as new radiocarbon dates for the level analyzed. The data contribute not only to regional archaeology, but also provide new elements for the understanding of the mortuary behavior of this archaeological unit along the De La Plata basin. discovered river th 510 (51 2 24 3 C AP. AP . AP) Chapecó analyzed archaeology basin 51 (5 5 (

RESUMO O surgimento do HIV impactou os serviços de saúde abruptamente em 1981, inicialmente afetando grupos sociais restritos. Atualmente, com o desenvolvimento da terapia antirretroviral, nos deparamos com uma doença diferente da encarada na década de 80, agora com uma evolução crônica. Todavia, algumas barreiras permanecem as mesmas, como o impacto social, mental e físico do diagnóstico na vida da pessoa que vive com HIV. O objetivo do presente estudo é verificar carga viral, contagem de linfócitos CD4+, e qualidade de vida de pessoas que vivem com o vírus da imunodeficiência humana. A presente pesquisa trata-se de um estudo observacional transversal com amostra de 24 indivíduos de ambos os sexos, com sorologia positiva para HIV, em acompanhamento médico sob tratamento antirretroviral. Foi utilizado um instrumento próprio para a coleta de informações sociodemográficas. Os resultados de contagem de CD4+ e a Carga Viral do HIV foram coletados dos prontuários médicos dos pacientes. A Qualidade de vida (QV) foi avaliada através do WHOQOL-HIV-BREF. Foi utilizada a análise descritiva para a caracterização do perfil da amostra. Os participantes (46,8± 9,2 anos) possuem ensino médio completo (41,8%), com renda de um a três salários mínimos (37,5%). Apresentam de um a três anos de diagnóstico e contagem de linfócitos CD4 acima de 500 mm3 de sangue (75%). Em relação à QV, os participantes apresentaram média mais alta para o domínio físico (26,7± 5,3) e mais baixa para os domínios de meio ambiente (10,9± 2,7) e relações sociais (12,2± 2,8). O estudo conclui que as pessoas que vivem com HIV participantes do estudo são adultos jovens, com renda e nível de escolaridade baixas, apresentam baixa qualidade de vida em relação aos domínios meio ambiente e relações sociais.

ABSTRACT The emergence of HIV abruptly impacted health services in 1981, initially affecting restricted social groups. Currently, with the development of antiretroviral therapy, we are faced with a different disease from the one seen in the 80s, now with a chronic evolution. However, some barriers remain the same, such as the social, mental and physical impact of the diagnosis on the life of the person living with HIV. The objective of the present study was to verify the viral load, CD4+ lymphocyte count, and quality of life of people living with the human immunodeficiency virus. This was a cross-sectional observational research with a sample of 24 individuals of both sexes, with positive serology for HIV, in medical follow-up under antiretroviral treatment. A specific instrument was used to collect sociodemographic information. CD4+ count and HIV viral load results were collected from patients’ medical records. Quality of life (QoL) was assessed using the WHOQOL-HIV-BREF. Descriptive analysis was used to characterise the sample profile. Participants (46.8± 9.2 years) have completed high school (41.8%), with an income of one to three minimum wages (37.5%). They present a three-year diagnosis and CD4 lymphocyte count above 500 mm3 of blood (75%). Regarding QoL, the participants had a higher average for the physical domain (26.7± 5.3) and lower averages for the environment domains (10.9± 2.7) and social relationships (12.2± 2.8). The study concludes that the people living with HIV who participated in the study are young adults, with low income and level of education, with a low quality of life in relation to the environment and social relations domains.

ABSTRACT Cowpeas are of high socioeconomic importance in the North and Northeast regions of Brazil, whereby the search for alternatives that offer increased productivity with financial returns has become an important challenge. Thus, the objective of this study was to estimate and evaluate the economic indicators of cowpea production in 2015 and 2016 when applying drip irrigation to different depths. Irrigation treatments were based on crop evapotranspiration (ETc). The experiment was laid in a randomized complete blocks design with four treatments (0, 25, 50, and 100% ETc) and six replications. For economic analysis, the results were extrapolated to an area of one hectare. Productivity in 2015 was lower than that in 2016; however, in all treatments, it was always higher when plants were grown under adequate water supply. In both years, the total operating costs were higher under irrigation than under rainfed conditions. The 100% ETc treatment resulted in a greater number of cowpea bags (60 kg) produced and a higher gross revenue than the rainfed treatment by 17 bags ha-1, equivalent to 1,020 kg ha-1 (gross revenue US$ 711.48) and 16 bags ha-1, equivalent to 960 kg ha-1 (gross revenue US$ 867.12), in 2015 and 2016, respectively. Water deficit limited cowpea yield in both years but made cultivation economically unfeasible only in 2015. Brazil challenge Thus 201 depths ETc. . (ETc) 0, 0 (0 25 50 100 replications analysis hectare however supply conditions 60 (6 1 ha1, ha1 ha 1, 1020 020 1,02 ha- US 711.48 71148 711 48 96 867.12, 86712 867.12 , 867 12 867.12) respectively 20 (ETc ( 2 5 10 6 102 02 1,0 711.4 7114 71 4 9 8671 867.1 86 711. 7 867. 8

RESUMO O feijão-caupi apresenta grande importância socioeconômica nas regiões Norte e Nordeste do Brasil, sendo que a busca por alternativas que ofereçam aumento de produtividade com retorno financeiro tem se tornado um importante desafio. Assim, o objetivo deste trabalho foi estimar e avaliar os indicadores econômicos da produção de feijão-caupi nos anos de 2015 e 2016 quando da aplicação de irrigação por gotejamento em diferentes lâminas. Os tratamentos de irrigação foram baseados na evapotranspiração da cultura (ETc). O experimento foi instalado em blocos ao acaso com quatro tratamentos (0, 25, 50 e 100% da ETc) e seis repetições. Para análise econômica, os resultados foram extrapolados para uma área de um hectare. A produtividade em 2015 foi inferior à de 2016; porém, em todos os tratamentos, a produtividade foi sempre maior quando as plantas foram cultivadas sob irrigação adequada. Em ambos os anos, os custos operacionais totais foram maiores sob irrigação do que sob condições de sequeiro. O tratamento 100% ETc resultou em maior número de sacas de feijão-caupi (60 kg) produzidas e receita bruta superior ao tratamento de sequeiro em 17 sacas ha-1, equivalente a 1.020 kg ha-1 (receita bruta US$ 711,48) e 16 sacas ha-1, equivalente a 960 kg ha-1 (receita bruta US$ 867,12), em 2015 e 2016, respectivamente. A deficiência hídrica limitou a produtividade do feijão-caupi nos dois anos, mas inviabilizou economicamente o cultivo apenas em 2015. feijãocaupi feijão caupi Brasil desafio Assim 201 lâminas ETc. . (ETc) 0, 0 (0 25 5 100 repetições econômica hectare porém adequada 60 (6 1 ha1, ha1 ha 1, 1020 020 1.02 ha- US 711,48 71148 711 48 96 867,12, 86712 867,12 , 867 12 867,12) respectivamente 20 (ETc ( 2 10 6 102 02 1.0 711,4 7114 71 4 9 8671 867,1 86 1. 711, 7 867, 8

ABSTRACT Context: Digital study models have become a safe and advantageous alternative for diagnosis and planning in dentistry. Despite the superior characteristics in comparison with traditional plaster models, professionals seem to resist the use of new technologies. Aims: To assess the level of knowledge and the use of digital models through a questionnaire applied to dental professionals. Methods: A questionnaire with 12 multiple-choice questions about plaster models, digital, and use of the 3Shape - 3D viewer software was answered by 76 orthodontists (42 women and 34 men; mean age =37.82 years (SD ± 7.60)) and 30 general dental surgeons (18 women and 12 men; mean age of 33.93 years (SD ± 8.45)) in Aracaju, Sergipe, Brazil. Data were tabulated in Excel spreadsheets and then analyzed using the SPSS statistical software version 20. An absolute analysis of frequency and percentage of responses was performed. Results: Most professionals reported using plaster models and claimed their low cost as justification for their use (P = 0.001). Aware of the benefits of digital models, professionals of both classes highlighted the facilitated storage and search for information as the main advantages, the cost and infrastructure as the main disadvantages. Regarding the use of the 3Shape - 3D viewer software, orthodontists showed better utilization of this resource than general dental surgeons (P = 0.0198). Conclusion: It verified that most professionals make use of plaster models. However, despite knowing the advantages of digital models, their cost is sees as a limiting factor for adherence to this technology. Context dentistry technologies Aims Methods 1 multiplechoice multiple choice Shape D 7 42 (4 3 men 3782 37 82 =37.8 SD 7.60 760 60 7.60) 18 (1 3393 33 93 33.9 8.45 845 8 45 8.45) Aracaju Sergipe Brazil 20 performed Results P 0.001. 0001 0.001 . 0 001 0.001) disadvantages 0.0198. 00198 0.0198 0198 0.0198) Conclusion However technology 4 ( 378 =37. 7.6 6 339 9 33. 8.4 84 2 000 0.00 00 0019 0.019 019 =37 7. 8. 0.0 0.01 01 =3 0.

RESUMO Contexto: Os modelos digitais de estudo têm se tornado uma alternativa segura e vantajosa para o diagnóstico e planejamento em odontologia. Apesar das características superiores em comparação aos modelos tradicionais de gesso, os profissionais parecem resistir ao uso de novas tecnologias. Objetivos: Avaliar o nível de conhecimento e a utilização de modelos digitais por meio de questionário aplicado a profissionais da área odontológica. Material e Métodos: Questionário com 12 questões de múltipla escolha sobre modelos de gesso, digitais e uso do software 3Shape - 3D viewer foi respondido por 76 ortodontistas (42 mulheres e 34 homens; idade média = 37,82 anos (DP = ± 7,60) ) e 30 cirurgiões-dentistas gerais (18 mulheres e 12 homens; média de idade de 33,93 anos (DP = ± 8,45)) em Aracaju, Sergipe, Brasil. Os dados foram tabulados em planilhas do Excel e posteriormente analisados no software estatístico SPSS versão 20. Foi realizada uma análise absoluta de frequência e percentual de respostas. Resultados: A maioria dos profissionais relatou utilizar modelos de gesso e alegou seu baixo custo como justificativa para seu uso (P = 0,001). Cientes dos benefícios dos modelos digitais, os profissionais de ambas as classes destacaram o armazenamento facilitado e a busca de informações como as principais vantagens, o custo e a infraestrutura como as principais desvantagens. Em relação à utilização do software 3Shape - 3D viewer, os ortodontistas apresentaram melhor aproveitamento desse recurso do que os cirurgiões-dentistas gerais (P = 0,0198). Conclusões: Verificou-se que a maioria dos profissionais faz uso de modelos de gesso. Porém, apesar de conhecer as vantagens dos modelos digitais, seu custo é visto como um fator limitante para a adesão a essa tecnologia. Contexto odontologia tecnologias Objetivos odontológica Métodos 1 Shape D 7 42 (4 3 homens 3782 37 82 37,8 DP 7,60 760 60 cirurgiõesdentistas cirurgiões dentistas 18 (1 3393 33 93 33,9 8,45 845 8 45 8,45) Aracaju Sergipe Brasil 20 respostas Resultados P 0,001. 0001 0,001 . 0 001 0,001) desvantagens 0,0198. 00198 0,0198 0198 0,0198) Conclusões Verificouse Verificou Porém tecnologia 4 ( 378 37, 7,6 6 339 9 33, 8,4 84 2 000 0,00 00 0019 0,019 019 7, 8, 0,0 0,01 01 0,