Abstract Fish hydrolysates have become one of the most remarkable sources of bioactive peptides. However, the processing conditions for incorporating hydrolysates into food matrices can affect their bioactive performance. The effect of temperature and pH on the radical scavenging activity of tilapia hydrolysate was determined in the wet hydrolysate. Also, a central composite design was used to study the effect of the drying conditions on moisture, drying ratio, productivity, drying rate, and antioxidant activity in the tilapia hydrolysate. The results showed that the hydrolysate has high activity at acidic and neutral pH; but at pH 10, the activity decreases significantly. In the spray-drying process, the antioxidant activity was higher at 115 °C. Moreover, inlet air temperature and feed flow had a statistically significant effect (p < 0.05) on response variables. High inlet air temperature and fast feed flow decrease the moisture of the powder hydrolysate and increase the drying rate and antioxidant activity. Scanning electron microscopy showed liquid bridges between particles with irregular concavities or pores on the surface and the presence of particle agglomerations due to the hygroscopicity of the hydrolysate. peptides However performance Also ratio productivity 10 significantly spraydrying spray process 11 C °C Moreover p 0.05 005 0 05 variables 1 0.0 00 0.

RESUMEN Antecedentes: El crecimiento de la producción acuícola en el mundo genera un importante impacto ambiental debido a su volumen de residuos, que alcanza casi el 60%. Estos subproductos tienen niveles importantes de proteínas y lípidos que pueden revaluarse para obtener productos que son de interés para las industrias farmacéutica y alimentaria, como péptidos bioactivos y propiedades funcionales. Recientemente, se han aplicado tecnologías para el aislamiento y la purificación de péptidos bioactivos de acuerdo con su peso molecular, así como técnicas de separación de membrana y cromatografía. Actualmente, hay productos comerciales de hidrolizados de proteína de pescado que pueden usarse en aplicaciones nutricionales y farmacéuticas como fuente de aminoácidos con diferentes funciones fisiológicas. Objetivo: Proporcionar información sobre subproductos de la acuicultura, métodos de hidrólisis, métodos de purificación, péptidos bioactivos, propiedades funcionales y suplementos nutricionales. Métodos: Se revisaron bases de datos como Science Direct, Springer Link, Wiley Online Library y Scopus usando palabras clave como productos de acuicultura, hidrólisis de proteínas, péptidos bioactivos, propiedades funcionales. Para la selección de los artículos se tuvo en cuenta el año de publicación, el idioma, la metodología empleada y la trayectoria de sus autores. Conclusiones: Esta revisión es una breve descripción del uso de subproductos acuícolas usando diferentes tipos de procesos de hidrólisis y sus múltiples aplicaciones en varias industrias.

ABSTRACT Background: Growing aquaculture production around the world generates an important environmental impact because of its waste volume, which reaches nearly 60%. These byproducts have important levels of protein and lipids that can be revaluated to obtain products that are of interest to the pharmaceutical and food industries such as bioactive peptides and functional properties. Recently, technologies have been applied to the isolation and purification of bioactive peptides according to their molecular weight, such as membrane separation techniques and chromatography. Currently, there are commercial products from fish protein hydrolysates that can be used in nutritional and pharmaceutical applications as a source of amino acids with different physiological functions. Objective: Give information on aquaculture byproducts, hydrolysis methods, methods of purification, bioactive peptides and functional properties and nutritional supplements. Methods: Science Direct, Springer Link, Wiley Online Library, and Scopus were reviewed using the keywords aquaculture products, protein hydrolysis, bioactive peptides, functional properties. For the selection of the articles, the year of publication, the language, the methodology used and the trajectory of the authors were taken into account. Conclusions: This review is a brief description of the use of aquaculture byproducts using different types of hydrolysis process and their multiple applications on several industries.