Wound dressing devices composed of microfibers of poly(butylene-adipate-co-terephthalate) and poly-(ε-caprolactone) incorporated with ibuprofen were obtained by electrospinning technique. The effect of ibuprofen concentration (0, 10, and 20% m m-1) on morphology, spectroscopic, and thermal characterization was evaluated. The fibers containing ibuprofen presented beads and revealed no uniformity. The spectroscopic analysis showed signals that reveal the ibuprofen incorporation on fibers. At the same time, X-ray diffraction spectroscopy indicated a difference in the fiber crystallinity depending on drug concentration, where a lower crystallinity was verified by the film containing a greater concentration incorporated. Rheological measurements revealed that films were more plastic in greater ibuprofen incorporation. Contact angle characterization revealed that ibuprofen solubilization on composite surfaces increased the film wettability. Finally, the fibers promoted the controlled release of ibuprofen, promoting morphological changes in polymeric matrices. The material developed can be used in future biomedical applications. polybutyleneadipatecoterephthalate poly butylene adipate co terephthalate poly(butylene-adipate-co-terephthalate polyεcaprolactone ε caprolactone poly-(ε-caprolactone technique 0, 0 (0 10 20 m1 1 m-1 morphology evaluated uniformity time Xray X ray wettability Finally matrices applications ( 2 m-

Polymeric films have been increasingly investigated due to the ease of miniaturization and integration in several sensor devices. Films obtained from the electrospinning technique have a controlled diameter and homogeneity, and substances can be incorporated into the polymeric network. Electrospinning fiber of chitosan (Ch) and poly(ethylene oxide) (PEO) was obtained from solutions prepared at different concentrations in acetic acid, and varying the distance and the voltage applied. The obtained films were characterized by scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), X-ray diffraction (XRD) and UV-Visible specular reflectance spectra (UV-SRS). The best conditions for electrospinning were obtained for a 2% m/v (Ch + PEO) solution in the ratio 90:10% m/m (Ch:PEO), applied voltage of 18 kV, and 18 cm distance between the capillary tube and collector. Acridine orange, sodium fluorescein, and erythrosine fluorescence dyes were successfully incorporated into Ch:PEO films. The spectrofluorometric spectra of the films showed excitation and emission processes and the acridine orange film showed evidence of excimer formation by the presence of an excitation peak at 569 nm. Ch-PEO films with the incorporation of fluorescent dyes may well be used as flexible probes or sensors in colorimetric devices in biochemical applications.