Abstract Jiménez-Díaz, J., Chaves-Castro, K. y Carpio-Rivera, E. (2023). Relationship between process- and product-oriented assessments of actual motor performance: a meta-analysis. PENSAR EN MOVIMIENTO: Revista de Ciencias del Ejercicio y la Salud, 21(1), 1-17. Motor performance is often assessed in two different ways. The first of them focuses on how the skill is carried out, whereas the second records the product obtained after execution. While both are widely used, the relationship between them is not clear. The objective of the present study is to determine the relationship between the results of process- or product-oriented tests that are used to measure actual motor performance, and to examine possible moderating variables through the meta-analytic technique. In order to sum up the products, the random effect model (REML) was used and the effect size (TE) of the correlation was calculated. A total seven studies met the criteria for eligibility, and a total 37 TE were obtained. It was found that a significant and positive relationship exists between process- and product-evaluated performance (TE = 0.466; IC95% = 0.391, 0.541; p < .001; n = 37; Q = 78.68; p < .001; I2 = 60.17%). Age and skill type were analyzed as possible moderating variables. The results suggest that a relationship exists between process- and product-oriented assessments of actual motor performance, while age and the type of skill have no influence on that relationship.

Resumo Jiménez-Díaz, J., Chaves-Castro, K. y Carpio-Rivera, E. (2023). Relação entre o desempenho motor real, avaliado por testes orientados a processos e a produtos: uma metanálise. PENSAR EN MOVIMIENTO: Revista de Ciencias del Ejercicio y la Salud, 21(1), 1-17. O desempenho motor é geralmente avaliado de duas maneiras; a primeira se concentra em como a destreza é realizada, enquanto a segunda registra o resultado obtido após a execução; ambas são amplamente utilizadas, no entanto, a relação entre elas não é clara. O objetivo do presente estudo foi determinar a relação entre os resultados de testes orientados a processos ou a produtos usados para medir o desempenho motor real e examinar possíveis variáveis moderadoras por meio da técnica metanalítica. Para resumir os resultados, foi utilizado o modelo de efeitos aleatórios (REML) e calculado o tamanho do efeito (TDE) da correlação. Um total de sete estudos cumpriram os critérios de elegibilidade, resultando em um total de 37 TDEs. Foi encontrada uma relação significativa e positiva entre o desempenho avaliado por processo e produto (TDE = 0,466; IC95% = 0,391, 0,541; p < 0,001; n = 37; Q = 78,68; p < 0,001; I2 = 60,17%). A idade e o tipo de habilidade foram analisados como possíveis variáveis moderadoras. Os resultados sugerem que existe uma relação entre o desempenho motor real, avaliado por testes orientados a processos e a produtos, idade e tipo de habilidade não influenciam esta relação.

Resumen Jiménez-Díaz, J., Chaves-Castro, K. y Carpio-Rivera, E. (2023). Relación entre el desempeño motor real evaluado con pruebas orientadas al proceso y el desempeño motor real evaluado con pruebas orientadas al producto: un metaanálisis. PENSAR EN MOVIMIENTO: Revista de Ciencias del Ejercicio y la Salud, 21(1), 1-17. El desempeño motor suele ser evaluado de dos formas; la primera se enfoca en cómo se realiza la destreza, mientras que la segunda registra el resultado obtenido después de la ejecución; ambas son ampliamente usadas, sin embargo, la relación entre ellas no está clara. El objetivo del presente estudio fue determinar la relación entre los resultados de las pruebas orientadas al proceso o al producto utilizadas para medir el desempeño motor real y examinar posibles variables moderadoras por medio de la técnica meta-analítica. Para resumir los resultados, se utilizó el modelo de efectos aleatorios (REML) y se calculó el tamaño de efecto (TE) de correlación. Un total de siete estudios cumplieron con los criterios de elegibilidad, se obtuvo un total de 37 TE. Se encontró que existe una relación significativa y positiva entre el desempeño evaluado por medio de proceso y producto (TE = 0.466; IC95% = 0.391,0.541; p < .001; n = 37; Q = 78.68; p < .001; I2 = 60.17%). Como posibles variables moderadoras se analizó la edad y el tipo de destreza. Los resultados sugieren que existe una relación entre el desempeño motor real evaluado por medio de pruebas orientadas al proceso y al producto, la edad y el tipo de destreza no influyen en dicha relación.

Background: In our country, transplantation centers differ in the age limit for allogeneic hematopoietic transplantation (ALOHT). In our program, transplants with age- adjusted conditioning are performed in patients until 70 years old. Currently more than 60% of ALOHT reported to the Center for International Bone Marrow Transplantation Research (CIBMTR) are performed in patients older than 40 years. Aim: To report our experience with ALOHT in acute myelogenous leukemia (AML), analyzing patient age at transplantation in different periods and transplant results in different age groups. Material and Methods: A retrospective analysis of the database of adult hematopoietic transplants in AML patients was performed. Demographic data, disease characteristics, transplant data, survival and relapse times, and mortality were collected. Results: In our program, 1030 transplants were performed in adults and 119 ALOHT were performed in AML patients, between 1990 and 2020. The median age of patients in all periods was 41 years, (range 16-69). The median age was 33 and 45 years, in the periods 1990-2000 and 2000-2020 respectively (p < 0.01). Seventy-eight patients received myeloablative conditioning (median age 44 years) and 41 reduced intensity conditioning (median age 53 years). Five-year overall survival was 44.6% (confidence intervals (CI) 41-48). Non relapse mortality of all periods was 19% (CI 17 - 40%) and relapse rate was 17 % (CI 16-22). No difference in five years overall survival among patients younger than 40, 41 to 50 and over 51 years was observed. Conclusions: Overall Survival, non-relapse mortality and relapse rate were similar in younger and older patients in our program and similar to those previously reported in other centers.

Resumen Actualmente, se recomienda el ejercicio contra resistencia (ECR) como una de las estrategias no farmacológicas para el control y tratamiento de la presión arterial (PA). Sin embargo, es necesario profundizar esta línea de investigación. El propósito del estudio fue comparar el efecto del tipo de descanso al realizar ECR sobre la PA de participantes normotensos. Participaron nueve hombres; siguiendo un diseño de investigación de medidas repetidas, realizaron tres condiciones experimentales en orden aleatorio: a) Descanso Activo (DA), b) Descanso Pasivo (DP), c) Sesión Control. En las 3 sesiones, se midió la PA y la frecuencia cardíaca (FC) pre-tratamiento, 1 minuto post-sesión y cada 10 minutos post-tratamiento durante 120 minutos. Las sesiones experimentales estuvieron precedidas por: mediciones antropométricas, familiarización y aplicación del test de 1RM. En el análisis estadístico se aplicó ANOVA de 2 vías para medidas repetidas, análisis de efectos simples y post hoc de Tukey. Entre los principales resultados, se encontró que, en comparación con la sesión control, los valores de PA disminuyen de forma significativa (p < .05): 1) al realizar ECR utilizando DP y DA a los 50, 100, 110 minutos post-ejercicio; 2) posterior a ejecutar ECR utilizando DA a los 20, 30, 70, 80,100, 120 minutos; 3) después de finalizada la sesión ECR con DP a los 10, 40 y 120 minutos. Respecto a la medición pre-test, los valores de PA disminuyeron de forma significativa (p < .05) a los 10, 20, 40, 50, 60, 100 y 120 minutos post ECR utilizando DP. En conclusión, al comparar con los valores de PA mostrados en un día de control, la ejecución de ECR aplicando DP y DA es funcional en el control de la PA de hombres jóvenes normotensos. En relación al pre-test, se podría indicar que el DP es el que promueve el efecto hipotensivo del ECR.

Resumo Recomenda-se, atualmente, o exercício contrarresistência (ECR) como uma das estratégias não farmacológicas para o controle e tratamento da pressão arterial (PA). Não obstante, é preciso aprofundamento nesta linha de pesquisa. O propósito do estudo foi comparar o efeito do tipo de descanso ao realizar ECR sobre a PA de participantes normotensos. Participaram nove homens; seguindo um desenho de pesquisa de medidas repetidas, realizaram três condições experimentais em ordem aleatória: a) Descanso Ativo (DA), b) Descanso Passivo (DP) e c) Sessão Controle. Nas 3 sessões, foram solicitadas a PA e a frequência cardíaca (FC) pré-tratamento, 1 minuto pós-sessão e a cada 10 minutos pós-tratamento durante 120 minutos. As sessões experimentais foram precedidas por: medições antropométricas, familiarização e aplicação do teste de 1RM. Na análise estatística aplicou-se a ANOVA de 2 vias com medidas repetidas, a análise de efeitos simples e o teste pós-hoc de Tukey. Entre os principais resultados, observou-se que, em comparação com a sessão controle, os valores de PA diminuíram de maneira significativa (p < 0,05): 1) ao realizar ECR, usando DP e DA nos 50, 100, 110 minutos pós-exercício; 2) posterior à execução do ECR usando DA nos 20, 30, 70, 80,100, 120 minutos; 3) depois de finalizar a sessão ECR com DP nos 10, 40 e 120 minutos. Com relação à medição pré-teste, os valores de PA diminuíram de maneira significativa (p < 0,05) nos 10, 20, 40, 50, 60, 100 e 120 minutos pós-ECR usando DP. Em conclusão, ao fazer a comparação com os valores de PA mostrados em um dia de controle, a execução de ECR aplicando DP e DA é funcional no controle da PA de homens jovens normotensos. Com relação ao pré-teste, poderia indicar-se que o DP é o promotor do efeito hipotensivo do ECR.

Abstract Resistance exercise is currently recommended as a non-pharmacological strategy to control and treat blood pressure, but further research is necessary concerning this topic. The purpose of this paper is to compare the effect of types of rest on the blood pressure of normotensive individuals while performing resistance exercise. Following a random methodological design with repeated measurements, nine men performed three experimental conditions on different days: a) Active Rest, b) Passive Rest, and c) Control Session. During the three sessions, blood pressure and heart rate measurements were taken pre-treatment, one-minute post-session, and every 10 minutes post-treatment for 120 minutes. Experimental sessions were preceded by anthropometric measurements, familiarization, and taking the 1RM test. The statistical analysis was conducted using two-way ANOVA with repeated measurements and Tukey post-hoc analysis. One of the main results indicated that, compared to the control session, blood pressure decreased significantly (p<0.05): 1) When performing resistance exercise with active and passive rest at 50, 100, 110 minutes post-exercise; 2) After executing resistance exercise with active rest at 20, 30, 70, 80,100, and 120 minutes; 3) After performing resistance exercise session with passive rest at 10, 40, and 120 minutes. With respect to pre-test levels, blood pressure decreased significantly (p<0.05) at 10, 20, 40, 50, 60, 100, and 120 minutes after performing resistance exercise with passive rest. In conclusion, compared with a control day, in the case of young normotensive males, the inclusion of both passive and active rest is functional for controlling blood pressure. In relation to the pre-test, passive rest promotes a hypotensive effect in the study population.

Resumen El propósito fue determinar el efecto del calentamiento activo con diferentes intervalos de recuperación en el rendimiento deportivo, en las pruebas de 50 y 200 metros libre. El estudio contó con la participación de 17 atletas (edad 13.5 ± 2.18 años), inscritos ante la Federación Costarricense de Deportes Acuáticos, con experiencia de entrenamiento y competición de 4.47 ± 1.28 años. Previo a la ejecución de las pruebas 50 y 200 metros libre, se realizaron 4 condiciones experimentales: Control (sin realizar calentamiento); Calentamiento (960 m) + descanso 20 min; Calentamiento (960 m) + descanso 10 min; Calentamiento (960 m) sin descanso. El orden de ejecución de las pruebas (50 y 200 metros libre) y la ejecución de las condiciones experimentales fueron asignadas de forma aleatoria. El análisis estadístico se realizó mediante ANOVA de una vía de medidas repetidas, p < 0.05. Los resultados indicaron que no existió diferencia significativa en el rendimiento en una prueba de 50 m libre (F = 0.83, p = 0.48) ni en la prueba de 200 m libre (F = 0.88, p = 0.46), al realizar un calentamiento activo respecto a no realizarlo. No hubo influencia de los diferentes tiempos de recuperación en el rendimiento en ambas pruebas. Se observaron diferentes patrones de respuesta individual a las condiciones experimentales. Se concluye que, de manera grupal, en nadadores jóvenes con poca experiencia, ejecutar un calentamiento activo previo a las pruebas de 50 y 200 metros libre, no mejora el rendimiento. Se recomienda que el entrenador ponga atención a la respuesta individualizada, para que elija el mejor protocolo (calentamiento o no) para mejorar el rendimiento deportivo de sus atletas.

Resumo O propósito foi determinar o efeito do aquecimento ativo com diferentes intervalos de recuperação no desempenho esportivo, nas provas de 50 e 200 metros livres. O estudo contou com a participação de 17 atletas (idade 13,5 ± 2,18 anos), inscritos na Federação Costarriquenha de Esportes Aquáticos, com experiência de treinamento e competição de 4,47 ± 1,28 anos. Previamente à execução das provas de 50 e 200 metros livres, foram realizados 4 condicionamentos experimentais: controle (sem aquecimento); aquecimento (960 m) mais descanso de 20 min; aquecimento (960 m) mais descanso de 10 min; aquecimento (960 m) sem descanso. A ordem de execução das provas (50 e 200 metros livres) e a execução dos condicionamentos experimentais foram atribuídas de maneira aleatória. A análise estatística foi realizada por meio da ANOVA de uma via de medidas repetidas, p < 0,05. Os resultados indicaram que não existiu diferença significativa no desempenho em uma prova de 50 m livres (F = 0,83, p = 0,48) e, tampouco, na prova de 200 m livres (F = 0,88, p= 0,46) ao realizar um aquecimento ativo em comparação a não o realizar. Não houve influência dos diferentes tempos de recuperação no desempenho em ambas as provas. Foram observados diferentes padrões de resposta individual aos condicionamentos experimentais. Conclui-se que, de modo grupal, em nadadores jovens com pouca experiência, realizar um aquecimento ativo prévio às provas de 50 e 200 metros livres, não melhora o desempenho. Recomenda-se que o treinador preste atenção na resposta individualizada para escolher o melhor protocolo (aquecimento ou não), buscando o aperfeiçoamento do desempenho esportivo de seus atletas.

Abstract The purpose of the paper was to determine the effect of active warm-ups with different recovery intervals in sport performance in 50m and 200m freestyle swimming. Seventeen athletes (13.5 ± 2.18 years old) registered with the Costa Rican Federation of Water Sports, with training and competition experience of 4.47 ± 1.28 years participated in this study. Before the 50m and 200m freestyle swimming tests, four experimental conditions were conducted: Control (without warm-up), Warm-up (960m) + 20 min rest, Warm-up (960m) + 10 min rest, Warm-up (960m) without rest. The order of the tests (50m and 200m freestyle) and the experimental conditions were randomly assigned. The statistical analysis used a one-way ANOVA of repeated measures, p < .05. No significant difference was found in performance in 50m or 200m freestyle swimming tests (F = 0.83, p = .48) (F = 0.88, p = .46), respectively, when using active warm-ups or not. Neither was there an effect of the different recovery times on performance in both swimming tests. Different patterns of individual responses were observed in the experimental conditions. It is concluded that, as a group, an active warm-up before 50m and 200m freestyle swimming tests does not improve the performance of young inexperienced swimmers. However, the coach is recommended to pay attention to individualized responses to select the best protocol (having warm-up or not) to improve athletes’ performance.

Abstract Introduction Patients with benign or malignant blood disorders, who require allogeneic stem cell transplantation and lack an identical human leukocyte antigen HLA identicalHL sibling donor, could be transplanted with hematopoietic stem cells from unrelated adult or umbilical cord donors. However, in our country, both approaches are costly and time-consuming options. Methods Over the last few years, haploidentical modalities have been investigated as an alternative donor source, showing similar results to those obtained with identical HLA donors. We started using T-cell-replete haploidentical with post-transplant cyclophosphamide in 2012 and we presented our experience with patients undergoing haploidentical ransplantation compared to SIB. Results Since January 2012 to date, 91 allogeneic transplants have been performed, of which 49 were haploidentical and 42 were HLA identical. The mean age of the patients was 35 years (range: 17–62). The mean CD34/kg × 106 infused per group was 5.93 and 5.89, respectively. Time to granulocyte and platelet engraftment was 11 and 15 days, respectively, for haploidentical, and 12 and 14 days, respectively, for HLA identical (p = 0.10). The 100-day cumulative incidence of global acute GVHD was 34% for haploidentical and 29% for SIHLA identical (p = 0.9). The 2-year overall global graft-versus-host disease was 43% for haploidentical and 41% for HLA identical (p = 0.8). Overall survival, relapse, and transplant and relapse-related mortality were similar between both groups. Conclusion Our experience showed that haploidentical has similar outcomes to those obtained with HLA idential and can be performed in our country safely.

Abstract Introduction: this study presents the results regarding diet and an analysis of natural estrogens (phytoestrogens) intake and how they affect other important aspects, which can modulate biological health functions among university students. Objectives: assessing nutritional habits and estimating the intake of phytoestrogens in the population under study. Materials and methods: Costa Rican female (n: 211, 18.83 ± 2.06 years) and male (n: 199, 19.64 ± 3.05 years) university population of the University of Costa Rica applied anthropometric tests using DEXA, the Food Frequency Questionnaire (FFQ) and the 24-hour Reminder (R-24). Results: the most serious nutritional bad habits were high ingestion of sodium, lipids and animal origin proteins in men and women and a deficit of fiber and folic acid in women. The total intake of phytoestrogens referred to: daidzein 0.23 ± 0.40 mg/day and 7.01 ± 11.94 mg/month in women and 0.17 ± 0.13 mg/day and 5.14 ± 3.96 mg/month in men; mainly consumed in the form of lignans 0.24 ± 0.12 mg/day (women) and 0.23 ± 0.14 mg/day (men). The intake of isoflavones was 0.09 ± 0.38 mg/day (women) and 0.04 ± 0.08 mg/day (men). Conclusions: the study population presented high fat percentage although the consumption of vegetables, cereals, whole grains and fruits tends slightly to be a Mediterranean diet; their food pattern was much closer to the Western diet.

Resumen Introducción: este estudio presenta resultados respecto a dieta y un análisis más en profundidad de la exposición a estrógenos naturales (fitoestrógenos) en la ingesta, y como este tipo de compuestos influye y se relaciona con otros aspectos importantes que pueden modular funciones biológicas relacionadas con la salud en estudiantes universitarios. Objetivos: valorar hábitos nutricionales y estimar la ingesta de fitoestrógenos de la población en estudio. Material y métodos: población costarricense universitaria femenina (n: 211, edades 18,83 ± 2,06 años) y masculina (n: 199, edades 19,64 ± 3,05 años) de la Universidad de Costa Rica y se han aplicado pruebas antropométricas mediante el DEXA y cuestionarios de Frecuencia de Consumo de Alimentos (FFQ) y Recuerdos de 24 Horas (R-24). Resultados: los errores nutricionales más graves fueron: la elevada ingesta de sodio, lípidos y proteínas de origen animal en hombres y mujeres, y el déficit importante de fibra y ácido fólico en las mujeres. La ingesta total de fitoestrógenos referidos a la daizdeína fue de 0.23 ± 0.40 mg/día y 7,01 ± 11,94 mg/mes en mujeres y de 0,17 ± 0,13 mg/día y de 5,14 ± 3,96 mg/mes en varones; principalmente consumida en forma de lignanos 0,24 ± 0,12 mg/día (mujeres) y 0,23 ± 0,14 mg/día (hombres), mientras la ingesta de isoflavonas fue de 0,09 ± 0,38 mg/día (mujeres) y de 0,04 ± 0,08 mg/día (hombres). Conclusiones: la población de estudio presentó porcentajes de grasa elevados nutricionalmente hablando, aunque el consumo de vegetales, cereales, granos enteros y frutas tiende un poco a la dieta mediterránea, su patrón alimentario se acerca mucho más a la dieta occidental.

ABSTRACT Introduction: age-related macular degeneration (AMD) is a degenerative disease of the retina, which causes loss of central vision in individuals older than 50 years. It is considered one of the most common causes of vision loss in Western countries and in developed countries it is the most frequent cause of low vision. Objective: to describe the behavior of visual rehabilitation, by performing fixation and localization exercises, in these patients. Method: a retrospective descriptive observational study was conducted in patients with age-related macular degeneration and visual functional diversity treated in low vision consultation of Granma province during February 2017 to January 2018; Macular degeneration associated with age is the second cause of visual functional diversity or blindness in the Granma province. Results: the tracking was more effective and there was motivation in the whole sample and in more than half of the cases the best corrected visual acuity increased, the reading speed improved, the fatigue disappeared, there was an adequate self-esteem and good Social insertion. Conclusions: all this shows that said rehabilitation improves visual capacity and promotes a higher quality of life.

RESUMEN Introducción: la degeneración macular asociada a la edad (DMAE) es una enfermedad degenerativa de la retina, que causa pérdida de la visión central en individuos mayores de 50 años. Es considerada una de las causas más comunes de pérdida de visión en países occidentales y en países desarrollados es la causa más frecuente de baja visión. Objetivo: describir el comportamiento de la rehabilitación visual, mediante la realización de ejercicios de fijación y localización, en estos pacientes. Método: se realizó un estudio observacional descriptivo retrospectivo en pacientes con degeneración macular asociada a la edad y diversidad funcional visual atendidos en consulta de baja visión de la provincia Granma durante febrero 2017 hasta enero 2018; La degeneración macular asociada a la edad constituye la segunda causa de diversidad funcional visual o ceguera en la provincia Granma. Resultados: fue más efectivo el rastreo y existió motivación en la totalidad de la muestra y en más de la mitad de los casos la agudeza visual mejor corregida de cerca aumentó, la velocidad de lectura mejoró, desapareció la fatiga, existió una adecuada autoestima y buena inserción social. Conclusiones: todo esto evidencia que dicha rehabilitación mejora la capacidad visual y propicia una mayor calidad de vida.

Abstract One of the main consequences of family dysfunction is codependency. The aim of this study was to investigate the relationship between family dysfunction and the development of codependent relationships among Mexican adolescents. Three scales were applied -The Scale Patterns of Family Structure Interaction, Argentinian Scale Codependency and Codependency Instrument- to 304 Mexican students, between the ages of 14 and 18. Results show that disunity was the most relevant characteristic in family dysfunction; while in codependency, the most relevant components were emotional confusion and rescuer tendencies. Disunity, fighting and triangulation were significant predictors of codependency by focusing on the other. Disunity, confusing hierarchies, and avoidance of conflict were significant predictors of codependency by self-denial. It was concluded that there is a strong relationship between family dysfunction and codependent behavior in adolescents.

Resumen Una de las consecuencias de las relaciones disfuncionales en la familia es la codependencia. El objetivo del presente estudio fue evaluar la presencia de codependencia en adolescentes mexicanos y su relación con la disfunción familiar. Se aplicaron tres instrumentos -la Escala de Patrones de Interacción de la Estructura Familiar, la Escala Argentina de Codependencia y el Instrumento de Codependencia-, a 304 estudiantes mexicanos entre 14 y 18 años. La desunión se observó como la característica más relevante en la disfunción familiar; mientras que en la codependencia, los componentes más importantes fueron la confusión emocional y la orientación rescatadora. La desunión, las peleas y la triangulación resultaron predictores significativos de la codependencia por focalización en el otro; la desunión, las jerarquías confusas y la evitación del conflicto predijeron la codependencia por autonegación. Se concluyó que existe relación entre la disfunción familiar y los comportamientos codependientes en los adolescentes.

Resumen Propósito: Conocer la asociación entre algunos factores de riesgo cardiovascular y la presión arterial en reposo de estudiantes universitarios costarricenses. Metodología: Una muestra total de 269 estudiantes universitarios (138 varones, 131 mujeres; edad promedio= 19,1 ± 2,8 años) respondieron instrumentos de medición sobre datos demográficos, antecedentes familiares de hipertensión, consumo de alcohol, cantidad de tragos ingeridos semanalmente, hábito de fumar, cantidad de cigarros fumados por día, cantidad de METs de actividad física realizada semanalmente y estado de salud general. Se obtuvo de cada sujeto la presión arterial sistólica (PAs) y diastólica (PAd) en reposo, índice de masa corporal (IMC), índice cintura/cadera (ICC), porcentaje de grasa determinado utilizando el densitómetro óseo (DEXA, marca General Electric) y consumo máximo de oxígeno (VO2max) de forma indirecta. Los datos obtenidos se analizaron mediante Regresión Lineal Múltiple, específicamente aplicando 2 Regresiones de Modelos Lineales Generales (MLG). Resultados: Las variables predictoras incluidas en el modelo explican 28,3% (R2model = 0,283) de la variación en la PAs y un 15,8% (R2model = 0,158) de la variación en la PAd. Los factores que predicen de forma significativa la PAs son Género (p = 0,02) e IMC (p = 0,001) y la PAd es el IMC (p = 0,004). La PAs en reposo, ajustado por la cantidad de cigarros fumados diariamente, la cantidad de tragos consumidos en una semana, el IMC, el ICC, el porcentaje de grasa corporal, el VO2max y la cantidad de METs de actividad física realizados semanalmente, fue 15,8mmHg mayor en hombres en comparación con las mujeres (p = 0,02). Por cada aumento de un kg/m2 en el IMC aumentaron 2,5mmHg y 1,5mmHg la PAs y PAd respectivamente. Conclusión: Al ser el IMC el factor de riesgo modificable, la opción para controlar y retrasar la aparición de hipertensión en jóvenes universitarios, es realizar esfuerzos para mantener un peso saludable en esta población.

Abstract Purpose: The study was designed to determine the association between selected cardiovascular risk factors and resting blood pressure in Costa Rican college students. Methods: Volunteers were 269 students (138 males and 131 females; mean age = 19,1 ± 2,8 yrs.), who completed questionnaires on demographics, family history of hypertension, alcohol intake, quantity of weekly liquor drinks, smoking habits, number of daily cigarettes smoked, physical activity (METs/week), and the general health status. In addition, measurements were obtained on resting systolic (SBP) and diastolic (DBP) blood pressure, body mass index (BMI), waist-to-hip ratio (WHR), percent body fat (% body fat) determined by full-body Dual Energy X-Ray Absorptiometry (DEXA, Lunar Prodigy, General Electric, Madison, WI), and maximum oxygen consumption (VO2max). Multiple regression analysis was used to assess the relationships between the 12 predictor variables using a general lineal model, with both, systolic (SBP) and diastolic (DBP) blood pressure as dependent variables. Results: The predictor variables entered in the model explained 28,3% (R2model = 0,283) of the variance of SBP values and 15,8% (R2model = 0,158) of the variance in DBP values. Gender (p = 0,02) and BMI (p = 0,001) were significant predictors of SBP, and BMI (p = 0,004) was a significant predictor of DBP. The mean SBP adjusted for the number of daily cigarettes smoked, quantity of weekly liquor drinks, BMI, WHR, % body fat, VO2max and METs/week was 15,8 mm Hg higher in males compared to females (p = 0,02). For every increment of 1 kg/m2 in BMI, both, SBP and DBP increased by 2,5 and 1,5 mm Hg, respectively. Conclusions: The modifiable risk factor BMI was associated to changes in both, SBP and DBP, in Costa Rican college students. Serious efforts should be made to achieve a healthy body weight in a population at high risk for hypertension.

Resumo A hipertensão arterial afeta 25% da população mundial e é considerada um fator de risco para distúrbios cardiovasculares e outras doenças. O objetivo deste estudo foi examinar as evidências sobre o efeito agudo do exercício sobre a pressão arterial (PA) utilizando medidas metanalíticas. Sessenta e cinco estudos foram comparados com tamanho de efeito (TE), testes de heterogeneidade, e teste Z para determinar se os TE eram diferentes de zero. A média dos TE globais corrigida para as condições do exercício foram -0,56 (-4,80 mmHg) para a PA sistólica (PAs) e -0,44 (-3,19 mmHg) para a PA diastólica (PAd; z ≠ 0 para todos; p < 0,05). A redução da PA foi significativa independente da PA inicial do participante, sexo, nível de atividade física, ingestão de medicamentos anti-hipertensivos, tipo de medição da PA, hora do dia na qual a PA foi medida, tipo de exercício realizado, e programa de treinamento (p < 0,05 para todos). Testes ANOVA revelaram que as reduções da PA eram maiores se os participantes eram do sexo masculino, não recebiam medicação anti-hipertensiva, eram fisicamente ativos e se o exercício realizado era jogging. Uma correlação inversa significativa foi encontrada entre idade e TE da PA, índice de massa corporal (IMC) e TE da PAs, duração da sessão de exercício e TE da PAs, e número de séries realizadas no programa de exercícios de resistência e TE da PAs (p < 0,05). Independente das características dos participantes e do exercício, houve uma redução na PA poucas horas após uma sessão de exercícios. No entanto, o efeito hipotensor foi maior quando o exercício foi realizado como uma estratégia preventiva em pessoas fisicamente ativas e sem medicação anti-hipertensiva.

Abstract Hypertension affects 25% of the world's population and is considered a risk factor for cardiovascular disorders and other diseases. The aim of this study was to examine the evidence regarding the acute effect of exercise on blood pressure (BP) using meta-analytic measures. Sixty-five studies were compared using effect sizes (ES), and heterogeneity and Z tests to determine whether the ES were different from zero. The mean corrected global ES for exercise conditions were -0.56 (-4.80 mmHg) for systolic BP (sBP) and -0.44 (-3.19 mmHg) for diastolic BP (dBP; z ≠ 0 for all; p < 0.05). The reduction in BP was significant regardless of the participant's initial BP level, gender, physical activity level, antihypertensive drug intake, type of BP measurement, time of day in which the BP was measured, type of exercise performed, and exercise training program (p < 0.05 for all). ANOVA tests revealed that BP reductions were greater if participants were males, not receiving antihypertensive medication, physically active, and if the exercise performed was jogging. A significant inverse correlation was found between age and BP ES, body mass index (BMI) and sBP ES, duration of the exercise's session and sBP ES, and between the number of sets performed in the resistance exercise program and sBP ES (p < 0.05). Regardless of the characteristics of the participants and exercise, there was a reduction in BP in the hours following an exercise session. However, the hypotensive effect was greater when the exercise was performed as a preventive strategy in those physically active and without antihypertensive medication.

MELAS syndrome is a rare mitochondrial cytopathy difficult to diagnose. We report the case of a 10year old girl who was admitted to the National Institute of Neurological Sciences of Lima - Peru, who presented sudden stroke like episodes and seizures. Neuroimaging studies showed infarction and genetic testing was positive for identifying the most common MELAS mutation(A3243).

El síndrome de MELAS es una rara citopatía mitocondrial de difícil diagnóstico. Reportamos el caso de una niña de 10 años, que ingresó al Instituto Nacional de Ciencias Neurológicas de Lima, Perú, quien presentó episodios bruscos similares a accidentes cerebro vasculares y crisis epilépticas. Los estudios de neuro imágenes mostraron infartos y el examen genético fue positivo para MELAS identificando la mutación más frecuente A3243G.