Abstract The current literature on guided bone regeneration (GBR) and guided tissue regeneration (GTR) membrane contamination reports that the physicochemical characteristics of these biomaterials might influence affinity to bacteria, which appears to be a major drawback for the clinical outcome of the regenerative procedures. Thus, this study aimed to evaluate, in vitro, a multispecies biofilm adherence and passage of bacteria through different types of commercially available membranes for GTR/GBR. Four types of membranes were tested (n=12): LC) Lumina Coat®; JS) Jason®; BG) Biogide®; and LP) Lumina PTFE®. Aluminum foil (AL) simulated an impermeable barrier and was used as the control. The membranes were adapted to specific apparatus and challenged with a mixed bacterial culture composed of A. actinomycetemcomitans b, S. mutans, S. mitis, and A. israelii. After 2 h or 7 days, bacterial adhesion and passage of bacteria were evaluated through CFU counting, which was analyzed by two-way ANOVA e post hoc Tukey, at a 5% significance level. Representative areas of two membranes of each group were analyzed through scanning electron microscopy (SEM) to assess the morphology and organization of the biofilm over the membrane fibers. LC and LP presented similar values of adhered bacterial cells (p > 0.05), significantly inferior when compared to the other groups, in both time points (p < 0.05). All the tested groups were permeable to bacterial cells, with no significant difference between the trial period of 2 h and 7 days (p > 0.05). SEM analyses demonstrated that adhered bacteria number increased throughout the time points (2 h < 7 days). Commercially available biological membranes demonstrated intense bacterial adherence and passage of bacteria, which increased throughout the trial period.

Resumo O objetivo deste estudo foi avaliar, in vitro, a aderência do biofilme multiespécie e a passagem de bactérias através dos diferentes tipos de membranas disponíveis comercialmente para RTG/ROG. Quatro tipos de membranas foram testados (n=12): LC) Lumina Coat®; JS) Jason®; BG) Biogide®; e LP) Lumina PTFE®. Papel alumínio (AL) simulou uma barreira impermeável e foi usado como controle negativo. As membranas foram adaptadas à um aparato específico e desafiadas com uma cultura bacteriana mista composta de A. actinomycetemcomitans b, S. mutans, S. mitis, e A. israelii. Após 2 h ou 7 dias, a aderência e passagem bacteriana foi avaliada através da contagem de UFCs. Duas membranas de cada grupo foram analisadas através da microscopia eletrônica de varredura (MEV). LC e LP apresentaram valores semelhantes de células bacterianas aderidas (p < 0.05), significativamente inferiores quando comparados aos outros grupos, em ambos os períodos experimentais (p < 0.05). Desde a análise inicial, todos os grupos testados foram permeáveis às células bacterianas, sem diferença significativa entre o período experimental de 2 h e 7 dias (p > 0.05). As análises em MEV demonstraram que o número de bactérias aderidas aumentou com o tempo (2 h < 7 days). Membranas biológicas comercialmente disponíveis demonstraram intensa aderência bacteriana e passagem de bactérias, que aumentou durante os períodos experimentais.

RESUMO Este artigo se propõe a investigar a trajetória do debate sobre redistribuição e tributação no Brasil no período pós-redemocratização, identificando fatores potencialmente favoráveis a reformas de caráter progressivo, bem como os obstáculos para sua implementação. Portanto, busca-se compreender, especificamente, a resiliência de um sistema tributário injusto em uma das democracias mais desiguais do mundo. A partir da literatura sobre o tema, propõe-se algumas hipóteses exploratórias que são analisadas de forma preliminar e indireta por meio da identificação de elementos sobre desigualdade e reforma tributária nas plataformas dos governos de Collor a Bolsonaro. pósredemocratização, pósredemocratização pós redemocratização, redemocratização pós-redemocratização progressivo implementação Portanto buscase busca compreender especificamente mundo tema propõese Bolsonaro

ABSTRACT This article investigates the trajectory of the debate on redistribution and taxation after redemocratization in Brazil, identifying factors potentially favorable to progressive reforms, as well as obstacles to their implementation. Specifically, it aims to understand the resilience of an unfair tax system in one of the most unequal democracies in the world. Following a literature review, some exploratory hypotheses are proposed and analyzed in a preliminary and indirect way through the identification of elements related to inequality and taxation in the political platforms of Brazilian Presidents, from Collor to Bolsonaro. Brazil reforms implementation Specifically world review Presidents Bolsonaro

RESUMO Introdução: Mastócitos podem participar da inflamação e contribuir para fibrose na nefrite lúpica (NL). Objetivo: Correlacionar mastócitos em biópsias renais (BR) de pacientes pediátricos com NL com índices de atividade (IA) e cronicidade (IC), avaliando sua efetividade como fator prognóstico. Metodologia: Foram estudados 40 pacientes, entre 6 e 18 anos, diagnosticados com NL pelo Serviço de Nefropatologia da UFTM entre 1996 e 2015. Dados laboratoriais e epidemiológicos foram correlacionados com IA, IC e contagem de mastócitos (CM). Resultados: Encontramos correlação positiva e significativa entre contagem de mastócitos (CM) e IA (p = 0,003; r: 0,66) e entre CM e IC (p = 0,048; r: 0,48). Conforme a curva Roc, os mastócitos têm alta sensibilidade e especificidade na diferenciação de pacientes com IA menor ou maior do que 12. A creatinina sérica foi mais elevada na classe IV em relação à classe V [1,50 (0,40 - 20,90) versus 0,70 (0,62 - 0,90), p = 0,04]. Ureia sérica apresentou correlação positiva e significativa com CM (p = 0,002; r: 0,75). Observou-se tendência à correlação negativa entre CM e albumina sérica (p = 0,06; r: -0,5459). BR de pacientes com síndrome nefrótica apresentaram maior CM [2,12 (0,41 - 5,140) versus 0,53 (0,0 - 3,94), p = 0,07]. Conclusão: Não apenas o infiltrado inflamatório como também a diferenciação morfológica dos tipos celulares que o constituem são importantes para a avaliação da NL. Isso indica que a análise dos mastócitos, juntamente com a dos IA e IC, pode ajudar os nefrologistas a definirem o prognóstico de pacientes pediátricos.

ABSTRACT Introduction: Mast cells may be involved in inflammation and contribute to the onset of fibrosis in lupus nephritis (LN). Objective: This study aimed to correlate the presence of mast cells in kidney biopsy specimens of pediatric patients with LN with activity (AI) and chronicity (CI) indices and assess how effectively mast cells may be used as a prognostic factor. Method: The study included 40 patients aged 6-18 years diagnosed with LN at the Renal Disease Service of the Federal University of Triângulo Mineiro between 1996 and 2015. Workup and epidemiological data were evaluated vis-à-vis AI, CI, and mast cell counts (MCC). Results: Significant positive correlations were found between mast cell counts (MCC) and AI (p = 0.003; r: 0.66) and MCC and CI (p = 0.048; r: 0.48). The ROC curve showed that mast cells were highly sensitive and specific in the differentiation of patients with an AI > 12 from individuals with an AI ≤ 12. Serum creatinine levels were higher in individuals with class IV LN than in patients with class V disease [1.50 (0.40-20.90) vs. 0.70 (0.62-0.90), p = 0.04]. Blood urea nitrogen had a positive significant correlation with MCC (p = 0.002; r: 0.75). A trend toward a negative correlation was observed between MCC and serum albumin (p = 0.06; r: -0.5459). Kidney biopsies of patients with nephrotic syndrome had higher MCC [2.12 (0.41-5.140) vs. 0.53 (0.0-3.94), p = 0.07]. Conclusion: Inflammatory cell infiltration and morphological differences between cell types in the inflammatory infiltrate are relevant factors in the assessment of the LN. Mast cell analysis and AI/CI assessment may be relevant prognostic indicators for pediatric patients with LN.

RESUMO Objetivou-se avaliar a produção, composição química e parâmetro de qualidade higiênico sanitária do leite de búfalas da raça Murrah criadas no semiárido nordestino. Foram utilizados dados de 13.752 observações de lactações coletados dos anos de 2013 a 2016 em plantel no Rio Grande do Norte. Foram avaliadas a qualidade do leite através da composição química (teores de gordura, proteína, lactose, e sólidos totais), contagem de células somáticas (CCS) e produção do leite. Os dados foram submetidos a correlação de Pearson, análise fatorial, análise de variância multivariada por ano e por período (seco, chuvoso e transição) e análise discriminante canônica por ano e por período. Correlação alta e positiva foi observada para sólidos totais e gordura (0,91), e correlação positiva para proteína e sólidos totais, produção e lactose. Por meio da análise fatorial, foram selecionados 3 fatores que explicaram 88% da variação total. O primeiro fator foi considerado "fator qualidade do leite", o segundo fator como "fator produção de leite" e o terceiro como "fator sanidade". Houve efeito significativo de ano e não significativo de períodos para as variáveis estudadas. Na análise discriminante canônica por ano as variáveis de poder maior discriminante foram (CCS), produção de leite e sólidos totais. Dentro de período, as variáveis mais discriminantes foram proteína, produção, lactose, gordura e sólidos totais. As análises multivariadas mostram-se eficiente na avaliação da produção e composição química do leite búfala, podendo ser usada com segurança em futuros estudos dessa natureza.

ABSTRACT The objective was to evaluate the production, chemical composition and hygienic -sanitary parameters of the milk of Murrah buffaloes raised in the northeastern semi-arid region. Data from 13,752 observations of lactations collected from the years of 2013 to 2016 from a herd in Rio Grande do Norte were used. The milk quality through chemical composition (contents of fat, protein, lactose, and total solids), somatic cell counts (CCS), and milk production was evaluated. Data were submitted to Pearson correlation, factorial analysis, multivariate analysis of variance per year, and per period (dry, rainy and transition) and canonical discriminant analysis by year and period. A high and positive correlation was observed for total solids and fat (0.91) and positive correlation for protein and total solids, yield, and lactose. Through factor analysis, four factors were selected that explained 88% of the total variation. The first factor was considered "milk quality factor, " the second factor as "milk production factor," and the third factor as " sanity factor." There was significant effect based on year but not significant effect based on period for the studied variables. In the canonical discriminant analysis per year, the discriminant power variables were (CCS), milk production and total solids. For periods were protein, production, lactose, fat, and total solids. Multivariate analysis was efficient in evaluating the production and chemical composition of buffalo milk and can be safely used in future studies.

RESUMO: Este artigo tem como objetivo a elaboração de uma análise sobre o processo de institucionalização da educação das relações étnico-raciais nas escolas que compõe a Rede Federal de Educação Profissional, Científica e Tecnológica. Para o encaminhamento da análise construímos alguns critérios de avaliação que tiveram como referência o documento relativo ao Plano Nacional de Implementação das Diretrizes Curriculares Nacionais para a Educação das Relações Étnico-raciais e para o Ensino de História e Cultura Afro-brasileira e Africana, de 2009. Estes critérios foram aplicados em uma análise que considerou o Plano de Desenvolvimento Institucional (PDI) de cada uma das instituições selecionadas a partir de perspectivas teóricas relativas à avaliação de políticas educacionais. Isso tornou possível a constatação de que há um nível muito baixo de institucionalização da educação das relações étnico-raciais nas escolas que compõe esta modalidade de ensino.

ABSTRACT: This article was elaborated with the objective of analyzing the process of institutionalization of racial relations education in schools that composes the Network Federal the Education of Professional, Scientific and Technological. In order to carry out the analysis, we constructed some criteria based on the document related to the National Plan of the Curricular Guidelines for Ethnic-Racial Relations Education and for the Teaching of Afro-Brazilian and African History and Culture - of 2009. These criteria were applied in a analysis that considered the Plan the Development Institutional (PDI) of the selected schools. This made possible the realization that there is a very low level of institutionalization of the education of ethnic-racial relations in the schools that compose this modality of education.

ABSTRACT CONTEXT AND OBJECTIVE: Choosing a medical specialty and making decisions concerning a career are difficult processes for medical students and newly graduated physicians.This exploratory study aimed to investigate the influence of role models on the choice of surgery as a career, and to determine the most influential model characteristics. DESIGN AND SETTING: Qualitative analysis on responses to a self-administered questionnaire, in different teaching-learning settings. METHODS: Residents from all years of various surgical subspecialties in a university hospital were included in a survey about the factors that determined their choice of surgery. The questions included items on whether a role model had influenced them in choosing surgery, and the personal or professional characteristics of the models that had been most influential. The responses were subjected to qualitative content analysis. RESULTS: Sixty-four out of 96 medical residents participated. Fifty-three residents (82.8%) acknowledged the influence of role models. Sixteen model characteristics were indicated as important, with 136 mentions. Characteristics classified as technical skills (55%), such as"medical knowledge"and "manual dexterity" predominated over humanistic characteristics (35%), such as "patient-physician relationships" and "ethical behavior". However, this difference was not statistically significant (Fisher test, P = 0.11).There were no age differences regarding the proportions mentioning "technical" and "non-technical" attributes, but female residents mentioned significantly more technical skills than their male colleagues did. CONCLUSIONS: The influence of role models seems to be an important factor determining the choice of surgery as a career. The influential characteristics of the models include not only technical but also humanistic qualities.

Resumo O tumor de Buschke-Loewenstein se caracteriza pelo crescimento excessivo de lesões verrucosas na região genital e/ou perianal. É considerado benigno apesar da elevada taxa de recorrência e da possibilidade de transformação maligna. Está comumente associado aos sorotipos 6 e 11 do papiloma vírus humano (HPV) e a imunidade do hospedeiro tem importante papel no desenvolvimento da doença. A excisão cirúrgica é o tratamento recomendado na maioria dos casos. Apresentamos o caso de uma paciente do sexo feminino, de 16 anos, com lesão vulvar de grande extensão tratada cirurgicamente com sucesso.

Abstract The Buschke-Loewenstein tumor is characterized by excessive growth of verrucous lesions on the genitals and/or perianal region. It is considered benign despite the high rate of recurrence and the possibility of malignant transformation. It is commonly associated with subtypes 6 and 11 of the human papillomavirus (HPV), and host 's immunity plays an important role in the development of the disease. Surgical excision is the recommended treatment in most cases. We present the case of a 16 years old female patient with extensive vulvar lesions successfully treated surgically.

Las avalanchas de escombros revisten una gran amenaza para las poblaciones aledañas a los volcanes. La rápida modificación de las geoformas dejadas por estos eventos hace difícil comprender la dinámica del deslizamiento, estimar su magnitud y evaluar el daño causado. Sin embargo, la prolongada preservación de los montículos a lo largo del curso de la avalancha se convierte en una herramienta para entender las características físicas de estos deslizamientos. En este trabajo se estudió un grupo de 281 montículos emplazados en el sector occidental del volcán Nevado del Ruiz en el área conocida como Las Nereidas. Se determinaron la distribución espacial y las dimensiones del emplazamiento mediante el posicionamiento con GPS en campo de los montículos individuales y el uso de ortofotos y topografía de alta resolución. Mediante la determinación del área de la base, se calculó una correlación negativa entre el área de los montículos individuales y su distancia a dos fuentes probables. Posteriormente, se determinó la fuente más probable para la avalancha y la dirección general de transporte, que fue en sentido NW, con cambios locales debido a controles topográficos. La movilidad (L/H) y su recíproco el coeficiente de fricción (H/L) se calcularon como 6,8 y 0,15, respectivamente. El análisis de la información investigada y los resultados permiten concluir que dicho emplazamiento corresponde a una avalancha de escombros con una edad inferior a 40.000 años, de magnitud menor, en la cual los materiales colapsaron desde una altura de 2,6 km y alcanzaron una distancia horizontal de 17,8 km (6,8 veces mayor que la altura de colapso), cubriendo un área total de 47,7 km² y transportando un volumen total de 5,05x10-3 km³, el cual se considera un valor subestimado.

Debris avalanches represent great hazard for communities neighboring volcanoes. Rapid modification of landforms during these processes makes it difficult understanding the dynamics of the slides, estimating their magnitudes and assesing their damage. The analysis of preserved hummocks along the path of avalanches, however, becomes a tool to interpret the physical characteristics of debris avalanches. In this work a group of 281 hummocks emplaced west of Nevado del Ruiz Volcano, in the Nereidas area, is studied. Both, the spatial distribution and dimensions of the emplacement are calculated using GPSdetermined positions of individual hummocks as well as orthoimages and high-resolution topography. A negative correlation is found between the base area of hummocks and their distances to two probable sources. The most likely source area for the avalanche and a NW general direction of transport with some topography controls were also determined. The mobility of the avalanche (L/H) and its reciprocal the friction coefficient (H/L) were determined as 6.8 and 0.15, respectively. Analysis of the information and the results lead to the conclusion that the deposit corresponds to a minor debris avalanche younger than 40000 years, during which materials collapsed from a height of 2.6 km and reached a horizontal distance of 17.8 km (6.8 times greater than the collapse height), covering a total area of 47.7 km² and transporting an estimated total volume equal to 5.05x10-3 km³, which is considered an underestimate.

Sanitary conditions are essential for the production of meals and control of the presence of pathogensis important to guarantee the health of customers. The aim of this study was to evaluate the sanitary quality of food services by checking the presence of thermotolerant coliforms, Staphylococcus sp. and evaluate the toxigenic potential from the latter. The analysis was performed on water, surfaces, equipment, ready-to-eat foods, hands and nasal cavity of handlers in seven food services. The water used in food services proved to be suitable for the production of meals. Most food, equipment and surfaces showed poor sanitary conditions due to the presence of thermotolerant coliforms (60.6%). Twenty-six Staphylococcus species were identified from the 121 Staphylococcus isolates tested. Staphylococci coagulase-negative species were predominant in the foods, equipment and surfaces. In food handlers and foods, the predominant species was Staphylococcus epidermidis. Twelve different genotypes were found after PCR for the classical enterotoxin genes. The seb gene (19.8%) was the most prevalent among all Staphylococcus sp. Both coagulase-positive and coagulase-negative Staphylococci showed some of the genes of the enterotoxins tested. We conclude that there are hygienic and sanitary deficiencies in the food services analyzed. Although coagulase-positive Staphylococci have not been present in foods there is a wide dispersion of enterotoxigenic coagulase-negative Staphylococci in the environment and in the foods analyzed, indicating a risk to consumer health.

OBJETIVO: Avaliar as variações do peso corporal e dos órgãos internos de crianças autopsiadas no período perinatal e sua relação com a causa de morte. MÉTODOS: Foram incluídos 153 casos de autópsias perinatais realizadas em um hospital universitário do Sudeste do Brasil. Informações sobre causa de morte perinatal, data da autópsia, idade gestacional, peso perinatal e dos órgãos foram recuperadas dos protocolos de autópsia e do prontuário da mãe e/ou do recém-nascido. Foram definidos quatro grupos de causa de morte: malformações congênitas, hipóxia/anóxia perinatal, infecção ascendente e membrana hialina. Encéfalo, fígado, pulmões, coração, baço, timo e suprarrenais foram analisados. RESULTADOS: O peso das crianças com hipóxia/anóxia perinatal (1.834,6±1.090,1 g versus 1.488 g), membrana hialina (1.607,2±820,1 g versus 1.125 g) e infecção ascendente (1.567,4±1.018,9 g versus 1.230 g) foi maior do que o esperado para a idade gestacional. O peso dos pulmões foi maior nos casos com infecção ascendente (36,6±22,6 g versus 11 g) e menor nos casos com malformação congênita (22,0±9,5 g versus 40 g). O peso do baço foi maior nos casos que apresentaram infecção ascendente (8,6±8,9 g versus 3,75 g ). O peso das suprarrenais foi menor nos casos com malformação congênita (3,9±2,1 g versus 5,5 g), o do timo foi menor nos casos com miscelânea (3,7±1,2 g versus 7,5 g) e o do baço foi menor nos casos com imaturidade pulmonar (0,4±0,1 g versus 1,7 g). Todos esses resultados apresentaram diferenças significativas. CONCLUSÕES: Este estudo demonstra que as variações do peso das crianças e de seus órgãos estão relacionadas aos tipos de causa de morte perinatal. Esses dados podem contribuir para uma melhor interpretação dos achados de autópsia e a sua relação anatomoclínica.

PURPOSE: To evaluate changes in body and internal organ weight of autopsied children in the perinatal period and their relationship with the cause of death. METHODS: One hundred and fifty three cases of perinatal autopsies performed at a university hospital in Southeastern Brazil ere included. Information about cause of perinatal death, date of autopsy, gestational age, perinatal weight and organ weight was obtained from the autopsy protocols and medical records of the mother and/or the newborn. Four groups of causes of death were defined: congenital malformations, perinatal hypoxia/anoxia, ascending infection and hyaline membrane. Brain, liver, lungs, heart, spleen, thymus and adrenals were analyzed. RESULTS: The weight of children with perinatal hypoxia/anoxi (1,834.6±1,090.1 g versus 1,488 g), hyaline membranes (1,607.2±820.1 g versus 1,125 g) and ascending infection (1,567.4±1,018.9 g versus 1,230 g) was higher than expected for the population. Lung weight was higher in cases with ascending infection (36.6±22.6 g versus 11 g) and lower in cases with congenital malformations (22.0±9.5 g versus 40 g). Spleen weight was higher in children with ascending infection (8.6±8.9 g versus 3.75 g ) and adrenal weight was lower in cases with congenital malformations (3.9±2.1 g versus 5.5 g). Thymus weight was lower in cases with miscellaneous causes (3.7±1.2 g versus 7.5 g) and spleen weight was lower in patients with lung immaturity (0.4±0.1 g versus 1.7 g). All results showed significant differences. CONCLUSIONS: This study demonstrates that variations in the weight of children and the weight of their organs are related to the types of cause of perinatal death. These data may contribute to a better interpretation of autopsy findings and their anatomical and clinical relationship.

OBJETIVO: Avaliar a influência das complicações maternas, da prematuridade, dos parâmetros antropométricos do feto e de condições do recém-nascido nos diferentes graus de corioamnionite. MÉTODOS: Foram analisadas 90 placentas provenientes de partos realizados no Hospital de Clinicas da Universidade Federal do Triângulo Mineiro com diagnóstico de inflamação no exame anatomopatológico. A revisão dos prontuários foi realizada para adquirir informações materno-fetais relevantes. A infecção foi classificada em: grau I - deciduíte; grau II - corioamnionite; grau III - corioamnionite e vasculite; grau IV - sepse neonatal; e grau V - morte fetal e pneumonite. RESULTADOS: Dentre as gestantes analisadas, 50,0% não apresentaram intercorrências, 15,0% apresentaram amniorrexe prematura, 15,0% infecção do trato urinário, 7,5% síndromes hipertensivas, 7,5% infecção transvaginal, 5,0% infecção hematogênica e 11,1% outras complicações. Mais da metade dos neonatos eram do sexo masculino e 72,2% a termo. Analisando o grau de corioamnionite, 56,7% apresentaram o grau I, 22,2 % grau II, 4,4% grau III, 10,0% grau IV e 6,7% grau V. Na análise estatística foi utilizado o Teste Χ2 para a análise de variáveis qualitativas e o Teste de Spearman para a análise das correlações. Os graus mais elevados de corioamnionite foram observados nos casos que apresentaram intercorrências maternas. Foram observadas correlações negativas entre todos os parâmetros fetais e o grau de corioamnionite, sendo significativa em relação ao peso, ao comprimento, à circunferência torácica e ao Apgar no primeiro e quinto minuto. CONCLUSÕES: Os diferentes padrões de corioamnionite estão relacionados a diferentes manifestações clínicas materno-fetais, influenciando nas condições de vida do recém-nascido e na gravidade de lesões morfológicas encontradas em natimortos.

PURPOSE: To evaluate the influence of maternal complications, prematurity, fetal anthropometric parameters and conditions of the newborn on different degrees of chorioamnionitis. METHODS: We analyzed 90 placentas from deliveries performed at the General Hospital of Triângulo Mineiro Federal University with a diagnosis of inflammation in the anatomopathological exams. We reviewed the medical records to obtain relevant maternal and fetal information. The infections were classified as grade I - deciduitis; grade II - chorioamnionitis; grade III - chorioamnionitis and vasculitis; grade IV - neonatal sepsis and grade V - fetal death and pneumonitis. RESULTS: Among the pregnant women analyzed, 50.0% had no complications, 15.0% had ruptured membranes, 15.0% urinary tract infection, 7.5% hypertensive disorders, 7.5% transvaginal infection, 5.0% hematogenous infection, and 11.1% other complications. More than a half the neonates were males and 72.2% were born at term. Analysis of the degree of chorioamnionitis showed that 56.7% had grade I, 22.2% grade II, 4.4% grade III, 10.0% grade IV, and 6.7% grade V. Data were analyzed statistically by the Χ2 test for qualitative variables and by the Spearman test for correlation analysis. The higher grades of chorioamnionitis were observed in cases of maternal complications. We observed negative correlations between all parameters and the degree of fetal chorioamnionitis, which were significant regarding weight, length, thoracic circumference and Apgar score in the first and fifth minutes. CONCLUSIONS: The different patterns of chorioamnionitis were related to different maternal and fetal clinical features, affecting the life conditions of the newborn and the severity of morphological lesions found in stillbirths.

Se estudió la actividad reproductiva de dos poblaciones de Anolis mariarum durante meses pertenecientes a las estaciones seca y lluviosa. El tamaño mínimo de madurez sexual fue comparable en los dos sitios, tanto para machos (37-39 mm LRC), como para hembras (44 mm LRC). Al nivel de población, la reproducción fue continua, encontrándose la mayoría de los adultos machos y hembras reproductivamente activos incluso en los meses de la estación seca. La distribución del tamaño de los juveniles también fue uniforme a lo largo de todos los meses, consistente con la conclusión de que el reclutamiento no es estacional en estas poblaciones. Sin embargo, se encontró evidencia de que algunas hembras pueden reducir su tasa reproductiva durante la estación seca, especialmente en la localidad que recibe menor precipitación total anual. Estos resultados apoyan la evidencia acumulada de que poblaciones de especies de Anolis habitando la región del "ecuador climático", en donde el régimen de precipitación anual es bimodal, son capaces de mantener una reproducción continua incluso cuando la cantidad de precipitación anual es relativamente baja, mientras que poblaciones de Anolis en áreas que reciben cantidades comparables de precipitación anual, pero durante una sola estación de lluvias, tienden a interrumpir la actividad reproductiva durante la estación seca prolongada cada año.

Reproductive activity was studied in two populations of Anolis mariarum during rainy and dry season months in the Antioquia department of Colombia. Minimum size at maturity was comparable at the two sites for both males (37-39 mm SVL) and females (44 mm SVL). At the population level, reproduction was continuous, with the majority of adult males and females reproductively active even during the dry season months. Juvenile size distributions also were uniform across seasons, consistent with the conclusion that recruitment is not pulsed in these populations. However, there was some evidence that certain females may lower their reproductive rates during the dry season, especially at the site receiving less total annual precipitation (1700 mm). These results further support accumulating evidence that populations of Anolis species inhabiting the "climatic equator" region, where the annual precipitation regime is bimodal, are capable of maintaining continuous reproduction even when annual precipitation amounts are relatively low. In contrast, Anolis populations in areas receiving comparable amounts of annual precipitation during a single rainy season tend to cease reproductive activity during the longer dry season each year.

The objective of this study was to evaluate clinical characteristics, etiology, and resistance to antimicrobial agents, among patients with ventilator-associated pneumonia (VAP). A case study vs. patients control under mechanical ventilation and hospitalized into clinical-surgical adults ICU of HC-UFU was performed from March/2005 to March/2006. Patients under ventilation for over 48 h were included in the study including 84 with diagnosis of VAP, and 191 without VAP (control group). Laboratory diagnosis was carried out through quantitative microbiological evaluation of tracheal aspirate. The identification of pathogens was performed by classical microbiological tests, and the antibiotics sensitivity spectrum was determined through the CLSI technique. VAP incidence rate over 1,000 days of ventilation was 24.59. The mean (± SD) duration of mechanical ventilation prior to VAP diagnosis was 23.2 ± 17.2 days. By multivariate analysis the risk factors predisposing for VAP were: mechanical ventilation time and mechanical ventilation > seven days, tracheostomy and use of > three antibiotics. Mortality rate was high (32.1 %) but lower than that of the control group (46.5%). Major pathogens were identified in most of patients (95.2%) and included: Pseudomonas aeruginosa (29%), Staphylococcus aureus (26%), Enterobacter/Klebsiella/Serratia (19%) and Acinetobacter spp. (18%), with expressive frequencies of P. aeruginosa (52%), S. aureus (65.4%) and Enterobacteriaceae (43.7%) resistant to imipenem, oxacillin and 3/4 generation cephalosporins, respectively. In conclusion, our observation showed VAPs caused by multiresistant microorganisms, the prescription of > three antibiotics, and mortality with unacceptably high rates. The practice of de-escalation therapy appears to be urgently needed in order to improve the situation.