Abstract Historically, since the 60's, traditional mine planning consists of several distinct stages: 1) Definition of the ultimate pit - the portion of the blocks that results in the greatest total value; 2) Pushback selection - based on the generation of nested pits, obtained with the change in the value of the ore price; 3) Long-term production scheduling. Although considered quite satisfactory, this methodology presents some flaws: The stages, even if considered individually optimal, may not be when put together. The opportunity cost is not considered and the cut-off is fixed. Due to the recent computational advances, a new technique has been growing and is more reliable: the direct block sequencing. In this methodology, the steps are consolidated into only one process, improving the economic results, reducing the total execution time and obtaining, in fact, an optimal planning. The aim of this work is to compare the results of the two planning methods applied in a database of a Brazilian iron ore mine and to show the real advantages and disadvantages of each one. To solve the direct block sequencing technique, Doppler was used, a tool developed by Delphos Mine Planning Laboratory, located at the University of Chile. The traditional methodology was executed through Whittle software. Lastly, a medium-term scheduling was performed using Deswik software.

Chandler's syndrome is a clinical variant of the iridocorneal endothelial syndrome in which the common aspect is the altered corneal endothelium that is sometimes very difficult to be diagnosed on account of the complexity and variability of signs and symptoms. This article was aimed at showing the effectiveness of specular microscopy for diagnosis. Here is a 67 years-old female patient who had significant reduction of vision in her left eye. On examination, there were observed severe corneal edema, pupillary mydriasis, mild corectopia towards the temporal sector with angled iridal traction and anterior angle synechias on the corectopia side. The endothelial counting revealed qualitative and quantitative alterations in the left eye. It was concluded that the specular microscopy is the key to diagnosis and assessment of suspected Chandler's syndrome cases

El síndrome de Chandler es una de las variaciones clínicas del síndrome iridocorneoendotelial, donde el denominador común es una alteración del endotelio corneal cuyo diagnóstico es, en ocasiones, muy difícil de realizar por la complejidad y la variabilidad de sus signos y síntomas. Se presenta una paciente de 67 años con disminución importante de la visión del ojo izquierdo. A la exploración existía un edema corneal severo, una midriasis pupilar, una corectopia leve hacia el sector temporal con tracción iridiana hacia el ángulo y sinequias anteriores angulares en el lado de la corectopia. La realización de un recuento endotelial demostró alteraciones cuali y cuantitativas del endotelio en el ojo izquierdo. Se concluyó que la microscopia especular es fundamental para el diagnóstico y la evaluación en casos sospechosos de síndrome de Chandler.