Resumo:
En
|
Texto:
En
|
PDF:
En
SUMMARY OBJECTIVE: This study aimed to investigate umbilical artery N-terminal proBrain natriuretic peptide (NT-proBNP) in fetuses delivered by cesarean section due to fetal distress in term pregnancies. METHODS: This prospective case-control study was conducted at the Antalya Training and Research Hospital Obstetric Department, Turkiye. A total of 140 pregnant women, 70 underwent elective cesarean sections between weeks 37 and 40 of gestation (Group 1, the control group) and 70 underwent cesarean sections due to fetal distress (Group 2, the study group), were included. The participants’ sociodemographic and obstetric data and fetal umbilical blood NT-proBNP levels were recorded in a database. RESULTS: Age, body mass index, gestational age, prenatal diagnostic tests, fetal anatomical scanning, and baby gender ratios were comparable between the groups (p>0.05), while statistically significant differences were observed in terms of gravidity (3.0 vs. 1.0, p≤0.001) and parity numbers (2 vs. 0, p≤0.001), baby height (50.36±0.88 vs. 49.80±0.86, p≤0.001) and weight (3422.43±409.16 vs. 3239.86±293.74, p=0.003), 1-min Apgar (9.0±0.1 vs. 8.5±1.3, p≤0.001) and 5-min Apgar (10.0±0.1 vs. 9.8±0.4, p=0.026) scores, umbilical artery pH (7.32±0.05 vs. 7.25±0.07, p≤0.001), umbilical artery base deficit (-2.48±1.23 vs. −4.36±1.09. p≤0.001), and NT-proBNP levels [8.77 (7.72–9.39) vs. 12.35 (9.69–12.92), p<0.001]. CONCLUSION: This study showed that NT-proBNP can be used as an important marker in the diagnosis of fetal distress. Prospective studies with more participants are now needed to confirm the accuracy of our results. OBJECTIVE Nterminal N terminal NTproBNP NT proBNP (NT-proBNP pregnancies METHODS casecontrol case Department Turkiye 14 women 7 3 4 Group 1 group 2 group, , included database RESULTS Age index age tests scanning p>0.05, p005 p p>0.05 0 05 (p>0.05) 3.0 30 (3. vs 10 1.0 p≤0.001 p0001 001 ( p≤0.001, 50.36±0.88 5036088 50 36 88 (50.36±0.8 4980086 49 80 86 49.80±0.86 3422.43±409.16 34224340916 3422 43 409 16 (3422.43±409.1 32398629374 3239 293 74 3239.86±293.74 p=0.003, p0003 p=0.003 003 p=0.003) 1min min 9.0±0.1 9001 9 (9.0±0. 8513 8 5 8.5±1.3 5min 10.0±0.1 10001 (10.0±0. 9804 9.8±0.4 p=0.026 p0026 026 scores 7.32±0.05 732005 32 (7.32±0.0 725007 25 07 7.25±0.07 2.48±1.23 248123 48 23 (-2.48±1.2 436109 09 −4.36±1.09 8.77 877 77 [8.7 7.72–9.39 772939 72 39 (7.72–9.39 1235 12 35 12.3 9.69–12.92, 9691292 9.69–12.92 69 92 (9.69–12.92) p<0.001. p<0.001 . p<0.001] CONCLUSION results p00 p>0.0 (p>0.05 3. (3 1. p≤0.00 p000 00 50.36±0.8 503608 (50.36±0. 498008 49.80±0.8 3422.43±409.1 3422434091 342 (3422.43±409. 3239862937 323 29 3239.86±293.7 p=0.00 9.0±0. 900 (9.0±0 851 8.5±1. 10.0±0. 1000 (10.0±0 980 9.8±0. p=0.02 p002 02 7.32±0.0 73200 (7.32±0. 72500 7.25±0.0 2.48±1.2 24812 (-2.48±1. 43610 −4.36±1.0 8.7 87 [8. 7.72–9.3 77293 (7.72–9.3 123 12. 969129 9.69–12.9 6 (9.69–12.92 p<0.00 p0 p>0. (p>0.0 p≤0.0 50.36±0. 50360 (50.36±0 49800 49.80±0. 3422.43±409. 342243409 34 (3422.43±409 323986293 3239.86±293. p=0.0 9.0±0 90 (9.0± 85 8.5±1 10.0±0 100 (10.0± 98 9.8±0 7.32±0. 7320 (7.32±0 7250 7.25±0. 2.48±1. 2481 (-2.48±1 4361 −4.36±1. 8. [8 7.72–9. 7729 (7.72–9. 96912 9.69–12. (9.69–12.9 p<0.0 p>0 (p>0. p≤0. 50.36±0 5036 (50.36± 4980 49.80±0 3422.43±409 34224340 (3422.43±40 32398629 3239.86±293 p=0. 9.0± (9.0 8.5± 10.0± (10.0 9.8± 7.32±0 732 (7.32± 725 7.25±0 2.48±1 248 (-2.48± 436 −4.36±1 [ 7.72–9 772 (7.72–9 9691 9.69–12 (9.69–12. p<0. p> (p>0 p≤0 50.36± 503 (50.36 498 49.80± 3422.43±40 3422434 (3422.43±4 3239862 3239.86±29 p=0 9.0 (9. 8.5 10.0 (10. 9.8 7.32± 73 (7.32 7.25± 2.48± 24 (-2.48 −4.36± 7.72– (7.72– 969 9.69–1 (9.69–12 p<0 (p> p≤ 50.36 (50.3 49.80 3422.43±4 342243 (3422.43± 323986 3239.86±2 p= 9. (9 10. (10 7.32 (7.3 7.25 2.48 (-2.4 −4.36 7.72 (7.72 96 9.69– (9.69–1 p< (p 50.3 (50. 49.8 3422.43± 34224 (3422.43 32398 3239.86± (1 7.3 (7. 7.2 2.4 (-2. −4.3 7.7 (7.7 9.69 (9.69– 50. (50 49. 3422.43 (3422.4 3239.86 7. (7 2. (-2 −4. 9.6 (9.69 (5 3422.4 (3422. 3239.8 (- −4 (9.6 3422. (3422 3239. − (342 (34