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Abstract The consumption and sharing of information on social media contribute to the circulation of false health content. In this sense, popular belief-driven posts recommending the use of amber necklaces to prevent symptoms of teething can be easily found on social media, even when they offer health risks for children. Accordingly, this study aimed to characterize posts in Portuguese by identifying message-based factors associated with higher user interactions of Facebook. A total of 500 Facebook posts published in Portuguese between August 2016 and August 2021 were retrieved by CrowdTangle, and analyzed quantitatively according to time of publication, total user interaction, and post overperforming score, and then qualitatively by two independent investigators, according to motivation, authors’ profiles, and sentiment. The data were evaluated by descriptive analysis, Mann-Whitney U test, chi-square test, and multiple logistic regression models regarding interaction metrics. The posts were published predominantly by commercial profiles, with social, psychological, and financial motivations, and expressed positive sentiment. Furthermore, time of publication (OR=2.65), regular user profiles (OR=3.30), and neutral/negative sentiment (OR=2.76) were associated positively with total interactions, whereas only time of publication was associated with post overperforming scores (OR=1.65). In conclusion, Facebook posts promoting efficacy of amber necklaces in managing teething symptoms are primarily created by commercial profiles with vested interests in marketing the product. The key factors that contribute to the success of posts containing false information about amber necklaces on Facebook can be identified by considering the author’s profile, sentiment, and time of publication. content sense beliefdriven belief driven children Accordingly messagebased message based 50 201 202 CrowdTangle score investigators motivation authors analysis MannWhitney Mann Whitney test chisquare chi square metrics psychological motivations Furthermore OR=2.65, OR265 OR OR=2.65 , 2 65 (OR=2.65) OR=3.30, OR330 OR=3.30 3 30 (OR=3.30) neutralnegative neutral negative OR=2.76 OR276 76 (OR=2.76 OR=1.65. OR165 OR=1.65 . 1 (OR=1.65) conclusion product author s profile 5 20 OR26 OR=2.6 6 (OR=2.65 OR33 OR=3.3 (OR=3.30 OR=2.7 OR27 7 (OR=2.7 OR16 OR=1.6 (OR=1.65 OR2 OR=2. (OR=2.6 OR3 OR=3. (OR=3.3 (OR=2. OR1 OR=1. (OR=1.6 OR=2 OR=3 (OR=3. (OR=2 OR=1 (OR=1. OR= (OR=3 (OR= (OR=1 (OR