RESUMO O objetivo deste trabalho foi comparar a eficácia dos modelos de Programação por Metas como ferramenta de regressão não linear, com os métodos de ajustes não lineares clássicos. Aplicou-se os modelos a dados experimentais de inativação de Salmonella spp. em carne móıda suína. A investigação da eficiência dos métodos foi realizada pelo cálculo do erro absoluto.

ABSTRACT The aim of this work was to compare the effectiveness of Goal Programming models, as a nonlinear regression tool, with the classical nonlinear fitting methods. The models were applied to experimental data of inactivation Salmonella spp. in ground pork. The investigation of the methods’ efficiency was made by calculation of the maximum and absolute errors.

RESUMO Neste artigo é proposto um modelo de programação por metas estendido aplicado ao planejamento de radioterapia, em que foi encontrada a melhor combinação de pesos para as metas a serem atingidas. O modelo foi aplicado a um caso real de câncer de próstata e resolvido pelo software CPLEX, em que foi utilizado o Método de Pontos Interiores Barreira Logarítmica como método de resolução.

ABSTRACT In this paper an extended goal programming model applied to radiotherapy planning is proposed, in which the best weight combination was found to each goal. The model was applied to a real prostate cancer case and solved by the software CPLEX, where Logarithmic Barrier Interior Point Method was used.

INTRODUCTION: Gloves made of natural rubber latex (NRL) are commonly used by healthcare workers because of their good qualities. However, allergic reactions to latex allergens are still commonly reported.OBJECTIVE: To measure the concentrations of Hev b 1, Hev b 3, Hev b 5 and Hev b 6.02 allergens in gloves used by a large laboratory service in South Africa.METHODS: NRL gloves as well as non-latex gloves supplied by various suppliers that were used by the laboratory personnel during the period June 2009 - May 2010 were obtained from various suppliers on the vendor list. Proteins were extracted from the gloves and Hev b 1, Hev b 3, Hev b 5 and Hev b 6.02 allergens were quantified using the FITkit assay.RESULTS: Twenty NRL gloves from 13 different brands were analysed. Only four (20%) of the 20 NRL gloves analysed had a total allergen content <0.15 μg/g, the suggested threshold limit for low allergenicity for the sum of these four allergens.CONCLUSION: This study demonstrated that a very low proportion of gloves tested had a total allergen content below the threshold for low allergenicity.

A new interpretation of the evolution of El Chichón volcano is presented in this paper based on photogeology, fieldwork, 40Ar/39Ar dating and chemistry of juvenile products. El Chichón volcano belongs to a volcanic complex formed by craters and peripheral domes with a total estimated volume of ~26 km³. Our data suggest that inception of magmatism began around 370 ka with the emission of lava domes buried by younger products. The activity continued with the formation of a large andesitic dome complex between 209 and 276 and associated block and ash flows and lahars. The dome complex was subsequently destroyed by a major eruption that left a 1.5-km wide Somma-type crater. The activity continued with the extrusion of the SW dome at 217 ka, that partially disrupted the southwestern Somma crater wall. Later on a series of dome extrusions occurred beyond the northwestern sector of the Somma crater at about 95 ka. Juvenile blocks found in 1982 products yielded ages of 44 and 29 ka attesting to heretofore unidentified late Pleistocene activity. The onset of Holocene activity occurred both outside the Somma crater with explosive eruptions that formed the Guayabal Tuff Cone and inside the Somma crater with the formation of a tuff cone that has been repeatedly reactivated during the Holocene, lastly during the 1982 eruption. All magmas produced during the past 370,000 years are K-alkaline andesites that exhibit minor variation in their chemical composition. An average discharge rate of 0.5 km³/ka is calculated during the past 8,000 years (~4 km³).

Se presenta una nueva interpretación de la evolución del Volcán Chichón con base en fotogeología, trabajo de campo, química y fechamientos de rocas con el método de 40Ar/39Ar. El Chichón forma parte de un complejo volcánico formado por cráteres y domos con un volumen total de ~26 km³. El magmatismo en el complejo inició hace 370,000 años con la emisión de domos de lava actualmente sepultados por depósitos recientes. La actividad continuó con la formación de un complejo dómico andesítico (209,000-276,000 años) y flujos piroclásticos y lahares asociados. Este complejo dómico fue destruido por una erupción mayor que dejó un cráter de 1.5 km de diámetro conocido como Somma. La actividad continuó con la extrusión del Domo SW, hace 217,000 años en el borde suroeste del cráter Somma y con domos externos emitidos más allá del borde noroeste del mismo cráter hace 95,000 años. Dos bloques embebidos en los depósitos de la erupción de 1982 proporcionaron fechas de 44,000 y 29,000 años, lo que indica que el complejo estuvo activo durante el Pleistoceno. Durante el Holoceno la actividad magmática formó el cono de tobas Guayabal y un cono de tobas al interior del cráter Somma que fue reactivado en varias ocasiones, la última durante la erupción de 1982. Durante los últimos 8,000 años el complejo volcánico ha producido ~4 km³ de material por lo que se estima una descarga de magma de 0.5 km³/1000 años. Las rocas del complejo volcánico son andesitas potásico-alcalinas muy homogéneas.