O objetivo deste estudo foi investigar a influência da dançaterapia na mobilidade funcional de crianças com paralisia cerebral hemiparética espástica. Participaram 10 crianças de sexo feminino, com idade média de 7.2 anos (± 1.2 anos) e diagnóstico de paralisia cerebral. Para avaliar a mobilidade funcional, utilizaram-se as dimensões D (em pé) e E (andar, correr e pular) da escala GMFM. Foram realizadas duas etapas, a primeira composta por seis semanas, em que as pacientes não eram submetidas a intervenção motora (etapa controle), e a segunda composta por 18 sessões de dançaterapia. As crianças foram avaliadas três vezes durante a pesquisa, sendo a primeira (I) antes da etapa controle; a segunda (II) após a fase controle; e a terceira (III) ao término da aplicação da dançaterapia. Os dados das dimensões D e E nas três avaliações foram analisados por meio do teste Kruskal-Wallis (p < .05), seguido do teste Dunn (p < .05). Nas duas dimensões, constatou-se que não houve mudança dos desempenhos entre a avaliação I e II (p = 1.00), permanecendo os participantes com itens similares. Entretanto, na avaliação III observou-se um aumento significativo em relação aos desempenhos das avaliações I e II para a dimensão D (p < .01) e E (p < .01). Os resultados demonstram que a dançaterapia propicia estímulos que influenciam a mobilidade funcional.

The aim of this study was to investigate the influence of dance therapy on the functional mobility of children with spastic hemiparetic cerebral palsy. Ten female children (mean age 7.2 ± 1.2 years) diagnosed with cerebral palsy were included. In order to evaluate their functional mobility, standing (D) and walking, running and jumping (E) dimensions from GMFM were applied, and measurements were carried out in two phases: 1) control, six weeks without any motor intervention, and 2) activity, 18 sessions of dancing. Children were assessed three times: first, before the control phase, second, after the control phase, and third, at the end of the dancing phase. Kruskal-Wallis (p < .05) and Dunn tests (p < .05) were used. There were no changes in performance between the two first phases of evaluation (p = 1.00), however, at the end of the dancing phase a significant increase was measured in relation to D (p < .01) and E dimensions (p < .01). Results showed that dance therapy influences children's functional mobility.

We determined the effect of an H1 receptor antagonist on the functional recovery of Carassius auratus submitted to telencephalic ablation. Five days after surgery the fish underwent a spatial-choice learning paradigm test. The fish, weighing 6-12 g, were divided into four groups: telencephalic ablation (A) or sham lesion (S) and saline (SAL) or chlorpheniramine (CPA, ip, 16 mg/kg). For eight consecutive days each animal was trained individually in sessions separated by 24 h (alternate days). Training trials (T1-T8) consisted of finding the food in one of the feeders, which were randomly blocked for each subject. Animals received an intraperitoneal injection of SAL or CPA 10 min after the training trials. The time spent by the animals in each group to find the food (latency) was analyzed separately at T1 and T8 by the Kruskal-Wallis test, followed by the Student Newman-Keuls test. At T1 the latencies (mean ± SEM) of the A-SAL (586.3 ± 13.6) and A-CPA (600 ± 0) groups were significantly longer than those of the S-SAL (226.14 ± 61.15) and S-CPA (356.33 ± 68.8) groups. At T8, the latencies of the A-CPA group (510.11 ± 62.2) remained higher than those of the other groups, all of which showed significantly shorter latencies (A-SAL = 301.91 ± 78.32; S-CPA = 191.58 ± 73.03; S-SAL = 90.28 ± 41) compared with T1. These results support evidence that training can lead to functional recovery of spatial-choice learning in telencephalonless fish and also that the antagonist of the H1 receptor impairs it.

The effect of post-training treatment with L-histidine (LH) on the memory consolidation of inhibitory avoidance was investigated in Carassius auratus submitted to cerebellar ablation. The inhibitory avoidance procedure included 3 days: one habituation day, one training day (5 trials, T1-T5) and one test day. On the training day, each fish was placed individually in a white compartment separated from a black compartment by a sliding door. When the fish crossed into the black compartment, a weight was dropped in front of it (aversive stimulus) and the time to cross was recorded. Saline or LH (100 mg/kg) was injected intraperitoneally 10 min after the trials. Data were log10 transformed and analyzed by ANOVA and the Student-Newman-Keuls test (P < 0.05). In T5, all groups [ablation/LH (N = 15; 189.60 ± 32.52), ablation/saline (N = 14; 204.29 ± 28.95), sham/LH (N = 14; 232.36 ± 28.15), and sham/saline (N = 15; 249.07 ± 25.82)] had similar latencies that were significantly higher than T1 latencies [ablation/LH (89.33 ± 20.41), ablation/saline (97.00 ± 25.16), sham/LH (73.86 ± 18.42), and sham/saline (56.71 ± 17.59)], suggesting acquisition of inhibitory avoidance. For the test, there was a significant reduction in latencies of ablation/LH (61.53 ± 17.70) and sham/saline (52.79 ± 25.37) groups compared to the ablation/saline (213.64 ± 29.57) and sham/LH (199.43 ± 24.48) groups, showing that cerebellum ablation facilitated retention of inhibitory avoidance and LH reversed the effect of ablation. The results support other evidence that LH impairs memory consolidation and/or reduces the interpretation of aversion value.