RESUMO Racional: As técnicas de endoscopia bariátrica são minimamente invasivas e induzem à redução do volume gástrico para tratar a obesidade. Objetivo: Avaliar a gastroplastia sleeve endoscópica (método Apollo) usando um método de sutura direcionado para a grande curvatura, bem como os cuidados perioperatórios, segurança em dois anos e perda de peso. Método: Estudo prospectivo em um único centro com 154 pacientes (108 mulheres) usando o procedimento endoscópico de gastroplastia sleeve sob anestesia geral com observação do paciente internado durante a noite. Dos 154 pacientes iniciais, 143 estiveram disponíveis para acompanhamento de um mês, 133 durante seis meses, 64 durante 12 meses e 28 completaram a avaliação de 24 meses. O acompanhamento foi realizado por equipe multidisciplinar (nutricionista e psicólogo). Foram avaliados nos resultados as mudanças no IMC, no peso corporal (TWBL), no % de perda do peso corporal inicial (% TBWL) no % de excesso de perda de peso corporal (%EWL) segregado em > ou < 25% e efeitos adversos. Estudos radiológicos contratados orais voluntários foram programados para avaliar a gastroplastia em diferentes tempos após o procedimento. Resultados: A idade média foi de 44,9 anos (23-69). Aos 24 meses após o procedimento a linha de base média do IMC mudou de 38,3 para 30,8 kg/m2. O TBWL, %TBWL e %EWL foram de 21,3 kg, 19,5% e 60,4%, respectivamente, e 85,7% dos pacientes alcançaram o objetivo de >25% EWL. Não houve eventos adversos graves peroperatórios ou durante os 24 meses de acompanhamento. Conclusão: A gastroplastia sleeve endoscópica com monitoramento regular por equipe multidisciplinar pode ser considerado procedimento eficaz, seguro e bem tolerado para o tratamento de pacientes com obesidade, pelo menos nos dois anos de acompanhamento.

ABSTRACT Background: Bariatric endoscopic techniques are minimally invasive and induce gastric volume reduction to treat obesity. Aim: To evaluate endoscopic sleeve gastroplasty (Apollo method) using a suturing method directed at the greater curvature, as well as the perioperative care, two year safety and weight loss. Method: Prospective single-center study over 154 patients (108 females) using the endoscopic sleeve gastroplasty procedure under general anesthesia with overnight inpatient observation. Of the154 initial patients, 143 were available for 1-month of follow-up, 133 for 6-month, 64 for 12-month and 28 completed the 24 month assessment. Follow-up was carried out by a multidisciplinary team (nutritionist and psychologist). Outcomes evaluated were: change in BMI; change in body weight (TBWL); % of loss of initial body weight (%TBWL); % of excess body weight loss (%EWL) (segregated in > or <25% and adverse effects. Voluntary oral contrasted radiological examinations were scheduled to assess the gastroplasty at different times post-procedure. Results: Mean age was 44.9 (23-69) years. At 24 months after the procedure baseline mean BMI change from 38.3 to 30.8 kg/m2. TBWL, %TBWL and %EWL were of 21.3 kg, 19.5% and 60.4% respectively. 85.7% of patients achieve the goal of >25% %EWL. There were no mayor adverse events intraprocedure or during the 24 months of follow-up . Conclusion: Endoscopic sleeve gastroplasty with regular monitoring by a multidisciplinary team can be considered an effective, safe and well tolerated procedure for obesity treatment, at least for two years of follow-up.

O estudo da corrosão microbiologicamente induzida é importante no setor de óleo e gás devido aos danos provocados pelos microrganismos aos sistemas de produção, armazenamento, transporte e qualidade do produto final. Os microrganismos podem ser encontrados amplamente distribuídos na natureza e o seu crescimento e produtos metabólicos podem comprometer o rendimento de indústrias petroquímicas. Um fator importante para o desenvolvimento de microrganismos é a presença de água e nutrientes no meio. Este trabalho teve como objetivo analisar a diversidade microbiana em diferentes amostras das indústrias do setor de óleo e gás e relacioná-la com os processos de biocorrosão.

The study of microbiologically induced corrosion is important to the oil and gas industry due to the damage caused by microorganisms to production, storage, and transportation systems and to the final product quality. Microorganisms can be found widely distributed in nature and their growth and metabolic products can compromise the performance of petrochemical industries. An important factor for the development of microorganisms is the presence of water and nutrients in the medium. This study aimed to analyze the microbial diversity in different samples of the oil and gas industries and to relate it to the biocorrosion process.

Injuries caused by venomous snakes are considered a problem of public health in Brazil, and further studies for a better knowledge are very important. The aim of this work is to describe clinical and epidemiological characteristics that were observed from 1995 to 2000 in the Hospital for Tropical Diseases of Araguaína, Tocantins State, Brazil, which is a unit of health that takes care of patients suffering from tropical diseases. We studied 440 individuals and the most common characteristics observed were masculine sex, age among 15-45 years, bite in low members, and injuries caused by snakes of the Bothrops genus. The signs and symptoms more frequently observed were edema, pain, erythema, and bleeding. The most observed systemic manifestation was alteration of blood coagulation. The most frequent complications were abscess, necrosis, bacterial infection, and renal failure. The mortality rate was 3%. These data are very important for the evaluation of the problem.